Publications

a selective inhibitor of camp-specific phosphodiesterase, ro 20-1724, has no effect on the quantal release of acetylcholine from the mouse phrenic nerve.	the indirect twitch response of the mouse isolated phrenic nerve-diaphragm preparation, partially paralysed by tubocurarine, was restored only by about 10% by ro 20-1724 at 2 to 280 microm. the solvent vehicle, dimethylsulphoxide, also showed the same effect to a similar extent. intracellular recordings with glass microelectrodes revealed that ro 20-1724 (40 microm) affected neither the resting membrane potential, the amplitude and frequency of miniature endplate potentials nor the amplitude of ...	1988	2897454
[atypical variant of cushing's syndrome].		2010	2897495
molecular neurobiology--a conference sponsored by the nimh.		2010	2902686
biological markers of suicide risk and adolescent suicide.		2010	2905935
improved sexual function in hemodialysis patients on recombinant erythropoietin: a possible role for prolactin.	as it was reported that correction of anemia in long-term hemodialysis patients by recombinant human erythropoietin (r-huepo) is associated with improved sexual function, we conducted the present study to further delineate the mechanism(s) by which this is brought about. serum prolactin, testosterone, and parathyroid hormone (pth) levels were followed during 4 months of r-huepo therapy. within 4 months of treatment with r-huepo, hematocrit values rose from 23.7 +/- 1.2 to 35.7 +/- 0.2% and hemog ...	1989	2914405
the protective effect of thromboxane synthetase inhibition on renal function in systemic sepsis.	to study the role of thromboxane in systemic sepsis and renal failure, peritonitis was induced surgically in 22 sheep, leading to local and systemic sepsis. a selective thromboxane synthetase inhibitor, u63,557a (upjohn co, kalamazoo, mi) was given before surgery in five animals and 30 minutes after surgery in five animals. a typical picture of volume-loaded, normotensive, vasodilated septic shock developed in all animals. twenty four hours after induction of sepsis, the control group showed a m ...	1989	2916566
a follow up of t-cell subsets and of anti-m. leprae antibody titer as measured by the fla-abs test in melanesian leprosy patients under polychemotherapy.	melanesian leprosy patients from new caledonia were studied for the following parameters during the course of polychemotherapy: peripheral blood t-cell subsets, as identified in an immunofluorescence assay with monoclonal antibodies okt3 ("pan-t"), okt4 ("helper/inducer"), and okt8 ("cytotoxic-suppressor"), and anti-mycobacterium leprae antibodies in the serum, as measured by the fluorescent leprosy antibody absorption test. a group of melanesian healthy subjects with no known exposure to m. lep ...	1986	2940306
some analyses of forgetting of pictorial material in amnesic and demented patients.	three experiments evaluating the rate of forgetting of pictorial stimuli in amnesic, demented, and normal control subjects are reported. when prolonged exposures of pictorial material were used to equate recognition performance after a 10-min delay, alcoholic korsakoff (ak) patients and patients with huntington's disease (hd) demonstrated normal rates of forgetting over a 1-week period. in addition to replicating previous findings with ak patients, these results are consistent with recent sugges ...	2010	2941450
dose-related effects of synthetic human beta-endorphin and naloxone on fed gastrointestinal motility.	in humans, plasma beta-endorphin levels rise during application of acute stressful stimuli (vertigo, cold pain, and transcutaneous electrical stimulation) that induce gut motor disturbances. whereas it is possible that circulating beta-endorphin participates in the mediation of these central effects on gut motility, its role cannot be established solely on the basis of changes in plasma levels. therefore, we designed the present study to investigate 1) the dose-related effects of intravenous syn ...	1986	2942039
structure-activity relationships of sex steroid analogs determined in vitro in a thyroid hormone-responsive membrane ca2+-atpase model.	physiological concentrations of l-t4 were found previously to stimulate ca2+-atpase activity in vitro in reticulocyte membranes from female rabbits and to inhibit this enzyme in reticulocyte membranes from males. in these previous studies, preincubation of intact cells or ghosts with testosterone (5 x 10(-11) m) converted female-source reticulocyte membranes to male-type responsiveness to thyroid hormone (inhibition of ca2+-atpase activity). preincubation of reticulocyte membranes with 17 beta-e ...	1986	2946570
structure-activity relationships of sex steroid analogs determined in vitro in a thyroid hormone-responsive membrane ca2+-atpase model.	physiological concentrations of l-t4 were found previously to stimulate ca2+-atpase activity in vitro in reticulocyte membranes from female rabbits and to inhibit this enzyme in reticulocyte membranes from males. in these previous studies, preincubation of intact cells or ghosts with testosterone (5 x 10(-11) m) converted female-source reticulocyte membranes to male-type responsiveness to thyroid hormone (inhibition of ca2+-atpase activity). preincubation of reticulocyte membranes with 17 beta-e ...	1986	2946570
[creatinine clearance in the elderly. comparison of results obtained by different methods of evaluation].		2010	2950506
alterations in the proliferative response of t cells from aged and chimeric mice.	factors involved in the nonspecific and specific proliferative responses of t cells were examined in the a/j strain of mice that were physiologically aged in the specific pathogen-free condition. in aged a/j mice, the production of il-1 and il-2 from optimally stimulated peritoneal macrophages and splenic t cells was significantly decreased, while the production of il-3 by t cells was increased. t cells from old mice showed a higher threshold for concanavalin a stimulation for the induction of i ...	2010	2953684
[fibrinolytic therapy of thromboembolic vascular occlusions: experiences based on 87 patients].		2010	2974192
cyclophosphamide, doxorubicin and cisplatin chemotherapy for patients with locally advanced urothelial tumors with or without nodal metastases.	thirty-eight patients with primary urothelial tumors recurring in the pelvis or nodal presentation were treated with intravenous or intra-arterial cyclophosphamide, doxorubicin and cisplatin chemotherapy. the 38 patients were selected owing to unresectability by local criteria (12 patients) or by virtue of nodal metastases (26 patients). histologically, the patients either had pure transitional cell carcinoma (29), transformation to a histological subtype of transitional cell carcinoma (7) or pu ...	2010	2993671
the biologic significance of the mixed lymphocyte kidney culture in humans.	the mixed lymphocyte kidney culture (mlkc) in humans has been studied in normal and abnormal clinical conditions. human renal cortical cells were extracted by collagenase treatment from the kidneys of "normal" heart-beating cadaver organ donors (n = 13), patients with end-stage renal disease (esrd) at pretransplant bilateral nephrectomy and splenectomy (n = 13), and from irreversibly rejected renal allografts at the time of graft nephrectomy (n = 5). proliferation of peripheral blood t lymphocyt ...	1985	2996186
occurrence of small hsd plasmids in salmonella typhi, shigella boydii, and escherichia coli.	the natural occurrence of small hsd (host specificity for dna) plasmids was demonstrated in restriction endonuclease-producing strains of salmonella typhi, shigella boydii, and escherichia coli. the five hsd plasmids isolated were between 5.0 and 12.2 kilobases long. the copy number of all the hsd plasmids was high (more than 10 copies per cell). introduction of these small plasmids into e. coli strain 0 drastically lowered the efficiency of plating of the lambda.0 phages (the efficiency of plat ...	1986	3003023
levobunolol for the long-term treatment of glaucoma.	systemically, levobunolol is as effective as propranolol for cardiovascular indications, with a greater potency and greater duration of action. ocularly, levobunolol is as effective and as safe as topical timolol for the long-term treatment of elevated iop. the utility of topical levobunolol as an additional, effective beta-blocker for the treatment of glaucoma will be determined by additional research and use by ophthalmologists in countries where levobunolol is approved.	2010	3019819
levobunolol for the long-term treatment of glaucoma.	systemically, levobunolol is as effective as propranolol for cardiovascular indications, with a greater potency and greater duration of action. ocularly, levobunolol is as effective and as safe as topical timolol for the long-term treatment of elevated iop. the utility of topical levobunolol as an additional, effective beta-blocker for the treatment of glaucoma will be determined by additional research and use by ophthalmologists in countries where levobunolol is approved.	2010	3019819
differential effects of transforming growth factor type beta on the growth and function of adrenocortical cells in vitro.	transforming growth factor type beta (tgf-beta) suppresses basal as well as corticotropin (acth)-stimulated steroid formation by bovine adrenocortical cells in culture. the effect is dose dependent and is not accompanied by any change in adrenocortical cell growth. the minimum effective dose of tgf-beta is 4 x 10(-13) m (10 pg/ml), and maximal inhibition is observed at a concentration of 4 x 10(-11) m (1 ng/ml). a 16- to 20-hr incubation with tgf-beta is required to decrease steroidogenesis, and ...	1986	3020557
differential effects of transforming growth factor type beta on the growth and function of adrenocortical cells in vitro.	transforming growth factor type beta (tgf-beta) suppresses basal as well as corticotropin (acth)-stimulated steroid formation by bovine adrenocortical cells in culture. the effect is dose dependent and is not accompanied by any change in adrenocortical cell growth. the minimum effective dose of tgf-beta is 4 x 10(-13) m (10 pg/ml), and maximal inhibition is observed at a concentration of 4 x 10(-11) m (1 ng/ml). a 16- to 20-hr incubation with tgf-beta is required to decrease steroidogenesis, and ...	1986	3020557
[multicentric chemodectoma].		2003	3020621
exposure of sheep to natural aerosols of foot-and-mouth disease virus.	sheep taken individually and allowed to inhale air being drawn along a duct from a cabinet containing pigs acutely infected with foot-and-mouth disease virus for 10 or 15 minute periods were infected by doses as low as 10 tcid50 of virus. the most consistent and reliable indicators of infection were viraemia and seroconversion. the mean times from exposure to onset of viraemia, pyrexia and the appearance of vesicular lesions were 2.5, 3.8 and 4.7 days, respectively. neither the time from exposur ...	1986	3020658
production of restriction endonucleases using multicopy hsd plasmids occurring naturally in pathogenic escherichia coli and shigella boydii.	a convenient procedure has been devised for detection of restriction endonucleases in the escherichia coli-shigella group. with this procedure, two restriction endonucleases, designated sbo 13 and eco t22, were found and later were identified as isoschizomers of nrui and avaiii, respectively. these endonucleases were shown to be produced from small multicopy plasmids. they were isolated from nonpathogenic e. coli into which the plasmids had been introduced by transformation, and purified from co ...	1986	3021586
relative activities of 5'-nucleotidase and adenosine deaminase in atrial and ventricular myocardium--the enzyme paradox.	the 5'-nucleotidase and adenosine deaminase activities were determined for tissue extracts of up to 10 defined regions of the normal dog heart. the specific activity of 5'-nucleotidase was very significantly higher in atrial than in ventricular myocardium (4 x) and was also higher in right than in left sites of the heart (2 x). the reason for the markedly higher specific activity in atrial muscle is not clear and appears paradoxical relative to adenine nucleotide content and pattern of atp decay ...	1986	3025011
communicating leveled clinical expectations to nursing students.	nurse educators agree on the need for objectives in the classroom situation and frequently communicate them in a written form. written expectations for clinical, however, are rarely given to student nurses prior to their clinical experience. clinical expectations are understood by instructors, but communicating them to students result in mixed interpretations. the article describes the development of a written method of communicating clinical expectations to solve this problem. this method corre ...	2010	3035139
the hypothalamic-pituitary-adrenal axis in depression.		2010	3035885
specificity of membrane complement receptor type three (cr3) for beta-glucans.	the binding of the ic3b receptor (cr3) to unopsonized zymosan was shown to result from cr3 attachment to cell wall beta-glucans. a specificity of neutrophil responses for beta-glucan was first suggested by a comparison of yeast (saccharomyces cerevisiae) cell wall components for stimulation of a neutrophil superoxide burst. neutrophils responded poorly to heat-killed yeast, but gave increasingly better responses to cell wall polysaccharides devoid of proteins (zymosan) and nearly pure beta-gluca ...	1987	3040332
shigella boydii and shigella sonnei: serotype and drug susceptibility patterns in addis ababa, ethiopia (1974-85).		1988	3042365
biphasic radiation-sensitivity of the transplantation immunity for rejection of an allogeneic ascites tumor.	transplantation immunity for second-set rejection of an allogeneic ascites tumor was induced by sensitizing mice with h-2-identical allogeneic spleen cells, and radiation-sensitivity of this immunity was studied. the immunity was not severely affected by 400 rads whole-body x-ray irradiation given at one day before the initial antigenic stimulation. in contrast, it was totally inactivated by 300-400 rads irradiation that was given one day before tumor challenge. an adoptive cell transfer experim ...	2011	3042613
congo red binding and salt aggregation as indicators of virulence in shigella species.	smooth strains of shigella dysenteriae type 1, shigella flexneri, shigella boydii, and shigella sonnei which form pigmented colonies (pcr+) on congo red agar were virulent in the sereny test. smooth variants unable to bind congo red (pcr-) were avirulent. measurements of dye uptake from solution showed that s. dysenteriae type 1 bound the most dye, followed in order of uptake by s. flexneri, s. boydii, and s. sonnei. using the salt aggregation test (sat) to determine cell surface hydrophobicity, ...	1988	3045151
the endocrine responses to general anesthesia.		2011	3049390
botulinum toxin a-induced protective ptosis in corneal disease.	botulinum toxin a produces a temporary, flaccid ptosis when injected into the levator palpebrae superioris muscle. the resulting protective ptosis was used to aid healing in 21 cases of indolent ulceration, and, prophylactically, in 4 cases of neuroparalytic keratitis. of the indolent ulcers, 90% healed completely. in all but one case, the cornea was covered completely by the lid and complete ptosis was produced in 75% of cases in an average of 3.6 days, lasting for 16 days on average before rec ...	2011	3050691
office evaluation and management of the shoulder impingement syndrome.	the shoulder impingement syndrome is the most common cause of shoulder pain. a complete office evaluation can be aided by a printed exam sheet. careful consideration of the differential diagnosis is important, often employing the xylocaine injection test. the impingement syndrome responds to conservative treatment the majority of the time. long follow-up determines the need for an invasive evaluation or surgical treatment.	2011	3050719
[etiologic structure of bacterial dysentery in the ussr in 1983-1985].	the etiological structure of dysentery in the ussr in 1983-1985 is characterized. sonne dysentery was found to prevail in the territories with adequate water supply, while dysentery caused by shigella flexneri prevailed at the territories with unsatisfactory water supply. s. dysenteriae and s. boydii were found to play a limited role in the etiology of dysentery. in the presence of global pandemic, an increase in the isolation rate of s. dysenteriae i in the ussr is observed. the data on the bio ...	1988	3061262
[use of prostacyclin in patients with ischemic stroke. a double-blind method ii].	thirty patients with acute ischaemic stroke were allocated randomly into a group treated with prostacyclin and a group receiving placebo. the treatment was started 24 to 72 hours after the onset of stroke. prostacyclin sodium (wellcome, u.k. or chinoin, hpr) or its solvent (glycine buffer) were administered intravenously once daily during 2 weeks in 6-hour infusions. prostacyclin was infused at rates of 2.5-5.0 ng/kg/min. statistically significant improvement appeared from the second day on in t ...	2010	3067105
[occupational asthma in the food industry].		2011	3067294
[academic dissertations of military pharmacists on the history of pharmacy].		2011	3067684
kluyvera species soft tissue infection: case report and review.	a soft tissue infection caused by kluyvera species in a previously healthy woman is described. successful treatment required incision and drainage of the wound in addition to administration of antibiotics. kluyvera species are indole positive, voges-proskauer negative members of the family enterobacteriaceae. previous reports of infection due to kluyvera species suggest that the organism is never more than an opportunistic pathogen; however, we report the first case of infection in a previously ...	1988	3068255
ciprostene in patients with peripheral vascular disease (pvd). an open-label, tolerance trial.	epoprostenol (prostacyclin) has been studied with various success in patients with peripheral vascular disease (pvd). we investigated the tolerance of a new, stable prostacyclin derivative ciprostene (9-beta-methyl carbacyclin) in 9 pvd patients. the drug was infused intravenously for 8 hours a day, once a week for 4 consecutive weeks, at a dose of 120 ng/kg/min. there were 6 men and 3 women with a mean age of 63 years (42-78). the pvd was verified by arteriography (9 patients) and by clinical f ...	2010	3068680
genetic relatedness of the basic replicon of the virulence plasmid in shigellae and enteroinvasive escherichia coli.	the regions required for replication (rep) and for stable maintenance (stb) of the 230 kilobase virulence plasmid, pmysh6000, in shigella flexneri 2a ysh6000 were identified on the restriction enzyme sa/l fragments, c and o, respectively. the stable plasmid, pmysh6610, consisting of adjacent fragments c and o was found to belong to the incompatibility group fl. in all strains of shigellae and enteroinvasive escherichia coli (eiec) tested, virulence plasmids were found to be highly homologous wit ...	1988	3070262
ultrasound in the diagnosis of splenic abscess. case report.		2011	3071730
[beef-extract agar with sodium nucleinate as a medium for storage and stabilization of biological properties of shigella].		1986	3078175
[shigella serotypes and drug resistance patterns of strains isolated in etimesgut, turkey, in 1987].	drug resistance patterns of shigella strains were investigated in a prospective manner in etimesgut district during a period of 1 year. thirty strains shigella were isolated, belonged to three subgroups with preponderance of sh. flexneri (70%), followed by sh. sonnei (27%) and sh. boydii (3%). the resistance was highest with streptomycin (80%), followed by trimethoprim-sulfamethoxazole (tmp-smz) (53%) and ampicillin (43%). only three strains (10%) were sensitive to all eight antibiotics tested. ...	1988	3078794
levels and sources of stress in medical students.	levels of stress, as measured by the general health questionnaire, were assessed in 318 medical students in their fourth year at three british universities. mean scores were higher than those in other groups within the general population, and the estimated prevalence of emotional disturbance was 31.2%, a proportion similar to that reported in medical students in the united states. there were no differences in prevalence or in mean scores of stress between the sexes. twelve (4%) students reported ...	2009	3085772
progestins and oral contraceptive-induced lipoprotein changes: a prospective study.	in order to determine the effects on plasma lipoproteins of oral contraceptives containing progestins with varying androgenic potency, 136 healthy women were randomized into 3 groups and followed prospectively for one year while receiving either 50 mcg ethinyl estradiol and 1.0 mg ethynodiol diacetate (eed), 50 mcg ethinyl estradiol and 1.0 mg norethindrone acetate (ena), or 50 mcg ethinyl estradiol and 0.5 mg d-1 norgestrel (eng). comparison was made to a self-selected group of 50 women using a ...	2011	3096633
aids policy development within the department of defense.		2011	3100984
[improved method of lipopolysaccharide isolation from gram-negative bacteria].	a modification of the traditional method for lipoplysaccharide isolation from the cells of grammnegative bacteria was elaborated on the basis of extraction by the hot water solution of phenol (the method of westfahl). to make the method simpler and to raise the yield of the product it was proposed to use the water-phenol extract without its division for plases. the nucleic acids are eliminated by precipitation from dialyzed extract at ph 3,2-3,4 achieved by addition of acetic acid. the comparati ...	1987	3112564
effects of cost sharing on physiological health, health practices, and worry.	in a randomized trial of the effects of medical insurance on spending and the health status of the nonaged, we previously reported that patients with limited cost sharing had approximately one-third less use of medical services, similar general self-assessed health, and worse blood pressure, functional far vision, and dental health than those with free care. of the 20 additional measures of physiological health studied here on 3,565 adults, people with cost sharing scored better on 12 measures a ...	2011	3119520
fiscal responsibility: prescription for survival.		2011	3121705
tuberoinfundibular dopaminergic function in parkinson's disease.	a deficit of nigrostriatal, mesocortical and mesolimbic dopamine systems in parkinson's disease is well known. we know less about the involvement of tuberoinfundibular dopamine (tid) systems. in untreated (naive or wash-out) men with parkinson's disease, we studied tid function through basal and stimulated plasma levels of growth hormone, prolactin and thyrotropin. only minor abnormalities in prolactin responses to thyrotropin-releasing hormone were found, probably reflecting denervation hyperse ...	2011	3133213
thermostable dipeptidase from bacillus stearothermophilus: its purification, characterization, and comparison with aminoacylase.	dipeptidase (dipeptide hydrolase [ec 3.4.13.11]) has been purified to homogeneity and crystallized from the cell extract of bacillus stearothermophilus ifo 12983. the enzyme has a molecular weight of about 86,000, and is composed of two subunits identical in molecular weight (43,000). the enzyme contains 2 g atoms of zinc per mol of protein. a variety of dipeptides consisting of glycine or only l-amino acids serve as substrates of the enzyme; km and vmax values for l-valyl-l-alanine are 0.5 mm a ...	1988	3139645
using computers to take patient histories.		2011	3147730
interferon alpha-2b as therapy for ph'-positive chronic myelogenous leukemia: a study of 82 patients treated with intermittent or daily administration.	the authors treated a total of 82 patients with ph'-positive chronic myelogenous leukemia (cml) with recombinant interferon alpha-2b (ifn alpha-2b). sixty-five patients in chronic phase (cp), 28 of whom were untreated and 37 pretreated, and nine patients in accelerated phase (ap), were started on ifn three times a week. patients in cp were randomized to receive 2 or 5 x 10(6) iu/m2, while patients in ap were all given the dose of 5 x 10(6) iu/m2, in addition to concomitant chemotherapy. patients ...	2011	3165298
cleavage lines of the oral mucosa in japanese cadavers.	cleavage lines were experimentally reproduced in the oral mucosa of japanese cadavers. they were investigated macroscopically and histologically. the reproduced cleavage lines showed little directional variation by sex or age. from the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria.	2011	3165386
activity of glucosidase inhibitors against hiv infections.		1988	3182426
[periarthritis of the shoulder. symptomology and classification].		2011	3187101
[rectosigmoid diffuse cavernous hemangioma].		2011	3187159
[continuing education. 28. subject: community nursing and administration. topic: the planning of changes in a primary care course].		2011	3187333
genotoxicity of carcinogens in human hepatocytes: application in hazard assessment.	evaluation of chemical genotoxicity has been used in assessing human cancer hazard, based on the observation that most human carcinogens are known to be dna-reactive. the availability of data on the dna-reactivity of compounds in metabolically competent human cells would assist hazard assessment by providing direct information of human genotoxicity. to evaluate the reliability of human hepatocytes for this purpose, the induction of dna repair by dna-reactive carcinogens of several structural cla ...	1988	3194919
ultrastructure of the sperm and spermatogenesis and spermiogenesis of dina lineata (hirudinea, erpobdellidae).	the mature sperm of dina lineata is of the modified type. the sperm are 48 micron long and 0.3 micron wide. the sperm are filiform and helicoidal cells with a distinct head, a midpiece, and a tail. there are two distinct regions in the head: the acrosome and the posterior acrosome, each with its own characteristic morphology. the midpiece is the mitochondrial region and has a single mitochondrion. two distinct portions can be observed in the tail: the axonematic region and the terminal piece. in ...	2011	3209181
perforations of the tympanic membrane following the use of goode-type 'long term' tympanostomy tubes.	a retrospective review of 64 goode 't' tube insertions is presented. these were inserted into 61 ears of 48 patients over a period of four years. at the time of review of these 61 ears, 34 tubes were found to be in situ, 27 had extruded spontaneously and three had been removed surgically. ten ears in which the tube had been extruded or removed had central perforations of the tympanic membrane of which eight had been present for more than six months. the number of previous myringotomies or gromme ...	2011	3209952
modeling of therapeutic dialysis of cerebrospinal fluid by epidural cooling in spinal cord injuries.	paraplegias of traumatic origin may be classified as primary or secondary. secondary traumatic paraplegia (stp) is believed to result from an autodestructive process. different authors have published results supporting or contradicting the therapeutic effects of durotomy alone or associated with exposed spinal cord and perfusion with a saline solution at normal or cold temperatures. it appears that although decompression and open dialysis might be beneficial, the surgical trauma over the injured ...	2006	3225857
intra-ocular pressure changes during rapid sequence induction of anaesthesia. a comparison between thiopentone and suxamethonium and thiopentone and atracurium.	the changes in intra-ocular pressure associated with two different anaesthetic induction and tracheal intubation techniques were compared (n = 30). after pre-oxygenation, group a received thiopentone (5 mg/kg) followed by suxamethonium (1.5 mg/kg), both within 25 seconds, and group b atracurium (0.5 mg/kg) followed by thiopentone (5 mg/kg) again both within 25 seconds. tracheal intubation occurred after one minute in group a and 2 minutes in group b to allow for full paralysis. in group a intra- ...	2011	3232776
an assessment of postoperative oxygen therapy in patients with fractured neck of femur.	arterial oxygen tension was studied in sixty patients with fractured neck of femur. the mean preoperative arterial oxygen tension was 63.7 mmhg (sd 12.8). half of the patients received nasal oxygen for five days postoperatively. in these patients, mean arterial oxygen tension was greater at all times than preoperative values, and exceeded values in those not receiving oxygen in whom no change in oxygen tension occurred until an increase on the fifth postoperative day.	2011	3232798
[results of conservative treatment of congenital dislocation of the hip--significance of arthrography].	to evaluate the clinical value of hip arthrography, especially two-directional arthrography, the author compared the treatment results of three different groups, group a: cases treated without arthrography, group b: cases treated using anteroposterior arthrography and group c: cases treated using two-directional arthrography. with lorenz's method, all three groups achieved about 40% success to g-i, ii by severin's classification. g-iii, iv was obtained in group a, b and c at 50.4%, 19.5% and 2.8 ...	2011	3249093
[results of conservative treatment of congenital dislocation of the hip--significance of arthrography].	to evaluate the clinical value of hip arthrography, especially two-directional arthrography, the author compared the treatment results of three different groups, group a: cases treated without arthrography, group b: cases treated using anteroposterior arthrography and group c: cases treated using two-directional arthrography. with lorenz's method, all three groups achieved about 40% success to g-i, ii by severin's classification. g-iii, iv was obtained in group a, b and c at 50.4%, 19.5% and 2.8 ...	2011	3249093
depression of intestinal epithelial cell production rate by hindgut bypass in rats.	influence of hindgut bypass on the epithelial cell production rates of the small and large intestine was tested in rats. hindgut bypass decreased cryptal cell production rates of the jejunum, ileum, cecum, and distal colon by 40-65%. these results suggest that the entrance of ileal effluent into the hindgut and, presumably, the resultant microbial production of short-chain fatty acids are required to maintain the normal epithelial cell proliferation not only in the hindgut but also in the small ...	1988	3249918
polypoid neurilemmoma of the trachea: an unusual cause of major airway obstruction.	neurilemmomas (schwannomas) of the trachea are extremely rare. a case of near-total obstruction of the trachea by an intraluminal polypoid neurilemmomas is reported. computerized tomographic imaging gave the exact localization of the polyp and the attachment of its stalk. endoscopic excision has left the patient with an excellent prognosis and little chance of recurrence.	2012	3250429
[principles of geriatric pharmacology. 1. pharmacokinetics and pharmacodynamics].		2012	3255626
the incidence of symptomatic urolithiasis in royal naval submariners comparison with personnel of the surface fleet.		2012	3256633
effect of indomethacin on febrile response to recombinant human interleukin 1-alpha in rabbits.	effects of indomethacin, a potent inhibitor of prostaglandin (pg) synthesis, on the fever induced by recombinant human interleukin 1-alpha (rhil 1-alpha) was studied in conscious rabbits. intracerebroventricularly administered rhil 1-alpha induced a dose-dependent increase in colonic temperature that was prominently suppressed by pretreatment with indomethacin given either intracerebroventricularly or subcutaneously. on the other hand, fever induced by intravenous administration of rhil 1-alpha ...	1988	3263055
shigellosis associated with recreational water contact in los angeles county.	an outbreak of shigellosis associated with swimming at a human-made lake during the labor day weekend occurred in los angeles county in 1985. sixty-eight persons had onset of diarrheal illness within 1 week following exposure at the recreational site. thirty-three of these cases were culture-confirmed as shigellosis (29 shigella sonnei, 4 shigella boydii). fifteen persons were hospitalized. illness was highly associated with water contact, specifically swallowing water while swimming (p less tha ...	1988	3275140
quality of commercially produced shigella serogrouping and serotyping antisera.	shigella grouping antisera from five manufacturers and typing antisera from two were purchased and evaluated with homologous and heterologous shigella strains in the slide agglutination test. only 31 of 73 (42%) antisera were satisfactory. in many instances, the antisera gave negative, as opposed to weak, reactions when they should have given strong positive reactions. four reagents cross-reacted with shigella strains. of the 19 polyvalent grouping antisera to subgroups shigella dysenteriae sero ...	1988	3281972
chiasmal compression caused by a catheter in the suprasellar cistern.		2009	3285696
large plasmid in shigella boydii is responsible for epithelial cell penetration.	a large plasmid in a virulent shigella boydii 5 strain was transferred to plasmid-cured avirulent strains of s. boydii 5, s. boydii 12, s. sonnei form ii, and escherichia coli k12. the transconjugants acquired the ability to invade tissue culture cells, which indicated that the large plasmid in s. boydii is responsible for epithelial cell invasiveness.	1988	3287107
[changes in the degree of sensitivity to antibiotics of shigella isolated from patients with dysentery in a city infectious disease hospital over the past 8 years].	changes in sensitivity of shigella and in particular shigella flexneri isolated from dysentery patients in a city infection hospital within 8 years i.e. from 1977 to 1985 were followed. it was shown that the changes were to the greater extent connected with preferable use of certain antibiotics in the hospital.	1988	3288150
redressing the balance.		2012	3292931
analysis of host-parasite coevolution.		2012	3294641
effects of marine mammal parasites on human health.		1987	3294653
an accessory protein identical to mouse egasyn is complexed with rat microsomal beta-glucuronidase and is identical to rat esterase-3.	we report biochemical, immunological, and genetic studies which demonstrate that an accessory protein with the essential features of mouse egasyn is complexed with and stabilizes a portion of beta-glucuronidase in microsomes of rat liver. the accessory protein exists as a complex with beta-glucuronidase since it coprecipitates with beta-glucuronidase after treatment of extracts with a specific beta-glucuronidase antibody. the two proteins are associated by noncovalent bonds since they are easily ...	1987	3294829
[the effect of radio- and chemotherapy on survival in advanced head and neck tumors].	inoperable cases of advanced squamous cell carcinomas in the head and neck area which have a very poor prognosis are often treated by a combined radio- and chemotherapy. tumor remissions up to 70% are induced by both radiotherapy and chemotherapy alone; an increase of the survival time is not reported. the present randomized study investigates the efficacy of two therapy schemes, i.e. chemotherapy alone and chemotherapy combined with irradiation. tumor remissions of 75% were achieved in 80 evalu ...	2012	3296260
epinephrine, glucose, and lactate infusion in exercising adrenodemedullated rats.	the purpose of this study was to determine the metabolic function of the marked increase in plasma epinephrine which occurs in fasted rats during treadmill exercise. fasted adrenodemedullated (adm) and sham-operated (sham) rats were run on a rodent treadmill (21 m/min, 15% grade) for 30 min or until exhaustion. adm rats were infused with saline, epinephrine, glucose, or lactate during the exercise bouts. adm saline-infused rats showed markedly reduced endurance, hypoglycemia, elevated plasma ins ...	1987	3298192
clinical presentation of shigellosis during the 1984 epidemic of bacillary dysentery in west bengal.		1987	3301795
[a reservoir of shigella of avian origin: herons and birds of prey of the zoological garden in tananarive].	the authors record the bacteriological characters of four shigella strains: s. dysenteriae 2 and s. boydii 9, respectively isolated in a bird-of-prey and in three herons, kept in the zoological garden in antananarivo. the significance of this malgasian avian reservoir of shigella is discussed.	1987	3304678
a new chromogenic test for the detection of urokinase in the genus shigella.	a simple test for detection of urokinase in shigella is described. the test is performed by suspending a loopful of bacteria in 100 microliters of a buffered 1mm solution of benzoyl-beta-alanyl glycyl-arginyl-4-nitroanilide acetate (chromozym u). enzymatic activity is revealed by formation of a yellow colour after 24 h of incubation at 37 degrees c. the test is able to differentiate serotypes of shigella dysenteriae, shigella flexneri, shigella boydii. the results suggest the possibility of incl ...	1987	3306294
expression of campylobacter jejuni invasiveness in cell cultures coinfected with other bacteria.	enteroinvasive salmonella, shigella, and escherichia coli strains were found to exert an effect which rendered campylobacter jejuni capable of intracellular localization in epithelial cells in vitro. when monolayers of hep-2 or a-549 cells were challenged with pure cultures of c. jejuni or campylobacter coli, none of the eight strains tested invaded the cells. in contrast, four of these strains were able to localize intracellularly when the cells were challenged with a mixture of campylobacters ...	1987	3312015
bactericidal activities of selected organic n-halamines.	the bactericidal efficacies of three organic n,n'-dihalamine disinfectants in the class of compounds termed imidazolidinones were determined for combinations of ph, temperature, and water quality treatments by using staphylococcus aureus and shigella boydii as test organisms. the compound 1,3-dibromo-4,4,5,5-tetramethyl-2-imidazolidinone was found to be the most rapidly acting bactericide, especially under halogen-demand-free conditions. the mixed n,n'-dihalamine 1-bromo-3-chloro-4,4,5,5-tetrame ...	1987	3314705
shigella bacteremia in adults. a report of five cases and review of the literature.	shigella bacteremia is rare, occurring mainly in children. we describe five adult patients with shigella bacteremia and review data on 22 cases reported in the english-language medical literature. eighteen (67%) of 27 patients had either an underlying condition or were aged older than 65 years. most patients had clinical signs of acute febrile gastroenteritis. however, in six patients, the organism was not isolated from stool. species isolated from blood included shigella flexneri in 11 patients ...	1987	3314766
glucoregulatory effects of bombesin in lean and genetically obese hyperglycaemic (ob/ob) mice.	1. plasma glucose and insulin responses to bombesin were examined in 12-15-week-old 12 hr fasted lean and genetically obese hyperglycaemic (ob/ob) mice. 2. bombesin (1 mg/kg ip) produced a prompt but transient increase of plasma insulin in lean mice (maximum increase of 50% at 5 min), and a more slowly generated but protracted insulin response in ob/ob mice (maximum increase of 80% at 30 min). plasma glucose concentrations of both groups of mice were increased by bombesin (maximum increases of 4 ...	2012	3315420
natural selection and the heritability of fitness components.	the hypothesis that traits closely associated with fitness will generally possess lower heritabilities than traits more loosely connected with fitness is tested using 1120 narrow sense heritability estimates for wild, outbred animal populations, collected from the published record. our results indicate that life history traits generally possess lower heritabilities than morphological traits, and that the means, medians, and cumulative frequency distributions of behavioural and physiological trai ...	2012	3316130
endoscopy-controlled study of the safety of nabumetone compared with naproxen in arthritis therapy.	nonsteroidal anti-inflammatory drug (nsaid) gastropathy is now a commonly recognized and reported complication of such arthritis therapy. significant gastric lesions develop in up to 40 percent of arthritic patients treated with long-term anti-inflammatory doses of nsaids, 20 percent of which represents actual ulcer crater disease. this 12-week endoscopy-controlled, double-blind study was constructed to evaluate the safety and efficacy of nabumetone 1,000 mg at bedtime compared with naproxen 250 ...	2012	3318424
double-blind clinical trial of s-adenosylmethionine versus ibuprofen in the treatment of osteoarthritis.	thirty-six subjects with osteoarthritis of the knee, the hip, and/or the spine were enrolled in a randomized double-blind study. patients received a daily oral dose of 1,200 mg of s-adenosylmethionine (same) or 1,200 mg of ibuprofen for four weeks. morning stiffness, pain at rest, pain on motion, crepitus, swelling, and limitation of motion of the affected joints were assessed before and after treatment. the total score obtained by the evaluation of all the individual clinical parameters improve ...	2012	3318445
arteriolar oxygen reactivity: where is the sensor?	the hypothesis that arterioles are intrinsically sensitive to oxygen was tested by comparing arteriolar diameter responses with local and global po2 changes in superfused hamster cheek pouch preparations. local po2 changes were produced by microapplication of fluid onto the surface of occluded or unoccluded aparenchymal arterioles or by cannulation and perfusion of arterioles in situ. global changes refer to po2 changes in the superfusate flowing over the entire preparation. local, effective po2 ...	2012	3318502
[medico-genetic studies of human provisional organs].		1987	3318529
novel oral vaccines: the effectiveness of cloned gene products on inducing secretory immune responses.		1987	3321939
differential clinical features and stool findings in shigellosis and amoebic dysentery.	to obtain information that could assist the clinician to differentiate between shigellosis and amoebic dysentery, we compared clinical features and stool findings in 58 adult male patients in bangladesh. mean values indicated that patients with invasive amoebiasis were older and had a longer prehospital illness, a lower body weight, less frequent fever, a lower haematocrit and a higher white blood cell count than patients with shigellosis. the mean number of faecal leucocytes per mm3 was signifi ...	1987	3328339
[chemical sympatholysis guided by computerized scanning].		2012	3346620
[tuberculosis in necropsies].		2012	3347110
[use of auxiliary measures within the scope of extracorporeal shockwave lithotripsy].		2012	3368891