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tracing neural connections of human brain with selective silver impregnation. observations on geniculocalcarine, spinothalamic, and entorhinal pathways.in selected human brains, it is possible to study the efferent connections of a damaged site with the suppressive silver impregnation techniques described by nauta and gygax. autopsy specimens with circumscribed lesions of recent origin ( one to five weeks before death) are suitable. however, the large size of the human brain and the lack of perfusion with fixative necessitates modifications in the methodology used on experimental animals. with these modifications, it has been possible to trace ...197992302
the relation of heart rhythm to postextrasystolic potentiation.in 9 patients with various forms of heart rhythms and rates, all of whom had a temporary pacemaker electrode inserted, several single premature ventricular contractions (pvc) with various coupling intervals (ci) were induced. the relative systolic area of the carotid pulse curve in the postextrasystolic beat was used as an indicator of the degree of postextrasystolic potentiation (pesp). a close correlation between pesp and ci was found only in sinus rhythm patients (r = -0.85). the patients wit ...200092314
augmentation of antigen-specific cytotoxicity by concanavalin a at the peak of response to tumor allografts. 200092366
cutaneous manifestations of acute carbon monoxide poisoning.a patient with acute carbon monoxide poisoning due to leakage of gas from the exhaust system in his automobile noted edema and blister formation over large areas of the skin of one half of his body. rhabdomyolysis, acute but transient renal insufficiency, and hemolytic anemia developed subsequently.200092389
[gamma globulin in secondary antibody deficiency syndrome].12 patients with secondary antibody deficiency syndrome received a new gammaglobulin compound intravenously (lyoph. srk sandoz). the drug was given in a 3% nacl-solution once to four times. at the end of the infusion of 6 g gammaglobulin and after one week, serum levels were significantly higher. gammaglobulin intravenously was well tolerated in all cases. severe infections during the period of treatment were not observed.200092444
populational polymorphisms in silver staining of nucleolus organizer regions (nors) in human acrocentric chromosomes.the ag stainability of the nucleolus organizer region (nor) was studied in the acrocentric chromosomes identified by q banding of cultured lymphocytes in 41 karyotypically normal persons (33 males and 8 females) originating from southeast estonia. the data obtained are compared with those established earlier for a combined vienna-ulm population of 51 karyotypically normal persons (see mikelsaar et al., 1977a). significant differences between the two populations in the frequency and patterns of a ...197992452
nonspecific light loss and intrinsic dna variation problems associated with feulgen dna cytophotometry.nonspecific light loss by the cell-wall-plus-cytoplasm (cwc) can cause a 50% increase in feulgen absorption units in peanut root-tip nuclei as determined by scanning at 450 nm, whereas this phenomenon is not evident with chicken erythrocytes. a two wavelength scanning method of subtracting nonspecific 450 nm absorption from 550 nm feulgen absorption values eliminated the nonspecific light loss in cwc, however, the two wavelength scanning method is time consuming and somewhat impractical with a r ...197992496
applications of microcomputer technology to cytophotometry.lack of appropriate software support for microprocessor program development has previously limited the applications of such technology in the field of microspectrophotometry. this paper describes our use of a vickers m86 integrating microdensitometer coupled through a custom-designed interface circuit to a processor technology sol iii microcomputer. w e have developed a series of interactive, user-oriented programs for dna-feulgen cytophotometry with this instrument to allow automatic storage of ...200092497
macrophage oxygen-dependent antimicrobial activity. i. susceptibility of toxoplasma gondii to oxygen intermediates.a sensitive method for evaluating extracellular parasite viability was used to determine the in vitro susceptibility of virulent toxoplasma gondii to selected oxygen intermediates. by acridine orange fluorescent staining criteria, toxoplasmas were resistant to up to either 10(-3) m reagent h2o2 or h2o2 generated by glucose-glucose oxidase. in keeping with a lack of sensitivity to h2o2, toxoplasmas contained endogenous catalase (5.7 x 10(-4) baudhuin units/10(6) organisms). the addition of a pero ...197992521
ia determinants on human t-cell subsets defined by monoclonal antibody. activation stimuli required for expression.the nature of ia antigens which appear on human t cells after activation and the stimuli required for their expression was examined utilizing a monoclonal antibody reactive with the ia antigen framework. t cells were purified using monoclonal antibodies directed either at the entire t-cell population (okt3) or the t-cell inducer subset (okt4). by indirect immunofluorescence, it was shown that the human t-cell population contains no detectable ia+ cells in the resting state. in contrast, in exces ...197992523
right/left differences of median nerve evoked scalp potentials in multiple sclerosis.scalp potentials evoked by electrical stimulation of the median nerve at the wrist were examined in multiple sclerosis patients and healthy controls. the latencies of the first negative peak (about 18 ms latency) of the response to right and to left-sided stimulation were compared. forty-eight of 60 measured latency differences in 15 suspected or certain ms patients were more than 3 standard deviations beyond the average difference in controls (arbitrary norm limit), whereas none of the 56 resul ...200192533
isotachophoresis of csf proteins in gel tubes especially gammaglobulins. an analytical and preparative technique for high-separation of csf proteins.an isotachophoretic method using polyacrylamide gel (pag-itp) in a simple disc electrophoretic equipment with plastic tubes containing the gels, was elaborated and especially designed for studying the gammaglobulins in csf and serum from control subjects and patients with neurological disorders, especially known or probable ms. the device and the itp system used, including leading and terminating electrolytes and spacer substances, dividing the gammaglobulins in a reproducible way, are described ...200192548
intrathecal igg synthesis in multiple sclerosis and other neurological diseases: a comparative evaluation by igg-index and isoelectric focusing.intrathecal igg synthesis has been investigated by determining the igg index and by isoelectric focusing in 30 cases of definite multiple sclerosis, in 15 cases of probable multiple sclerosis and in 128 patients affected by other neurological diseases. the blood-brain barrier function was evaluated at the same time by serum albumin/csf albumin quotient and isoelectric focusing. the igg index was found elevated in 73.3% of definite multiple sclerosis patients, while oligoclonal igg bands occurred ...200192550
antigenic make-up of trypanosoma cruzi culture forms: identification of a specific component.a comparison of trypanosoma cruzi water soluble antigens with those of stercorarian and salivarian trypanosomes, and leishmania using immunoprecipitation in gels and immunoelectrophoresis, with the aid of hyperimmune rabbit serum and heterologous adsorptions showed the following. 1) there is a high complexity of soluble antigens of t. cruzi and t. rangeli. 2) at the intraspecific level our results demonstrated the antigenic stability of t. cruzi when maintained in vitro, and that there was quant ...197992559
biologically active polycycloalkanes. 6. antiviral 1-tricyclo[4.3.1.1 2,5]undecyl derivatives.functionalization reactions via cationic intermediates of tricyclo[4.3.1.1 2,5]undecane (2) were investigated to prepare derivatives with potential antiviral activities. bromination of 2 took place regiospecifically at c-1, and the resulted bromide 5 was converted into the hydroxide 9, the carboxylic acid 12, and the amine 22, from which were synthesized a variety of secondary derivatives, including homologous esters 10 and 20, amides 14 and 19, carbamates 24, and ureas 17 and 25. the hydroxide ...197992566
cytotoxic enteropathogenic escherichia coli. 197992636
why blame cholesterol? 200192723
osmiophilic reagents in electronmicroscopic histocytochemistry.direct histocytochemical staining methods on undisrupted tissues, stabilized by chemical fixation, potentially offer perhaps the most reliable approach to the study of the enzymes of the cell with relation to its ultrastructure. the atoms which, for the most part, comprise the biomacromolecules and enzymes of cells and tissues contribute little to their inherent electron opacity or ability to scatter electrons differentially. the latter property of a substance is responsible for its observation ...197992799
language deficits after apparent clinical recovery from childhood aphasia.twenty-seven children with childhood injury to the left hemisphere were tested for language function and compared with appropriate controls. eleven children had incurred their lesions before the age of 1 year, 16 afterward. the group with perinatal injury to the left hemisphere did not show a specific aphasic deficit even though they were mildly cognitively impaired. the group of children with later injury to the left hemisphere showed aphasic deficits if the original injury had caused a languag ...200192909
isolation and cell culture propagation of rotaviruses from turkeys and chickens.rotaviruses were detected by electron microscopy in the faeces of turkey poults and broiler chickens with diarrhoea. apparently symptomless infection was also observed in broilers. the avian rotaviruses could not be isolated in cell cultures by conventional techniques, but were adapted to serial growth in chick cell cultures following trypsin treatment of the virus and the cells. immunofluorescence studies showed that the avian and mammalian rotaviruses are antigenically related. antibodies to r ...197992979
[photocoagulation of late complications of retinal venous occlusions (analysis of 22 cases treated for 1 to 5 1/2 years)]. 200193028
[palliative non-surgical bile duct drainage]. 200193044
binding of bursal, thymic and splenic lymphocytes to macrophages. 197993085
an exploration of a patient-centred nursing approach in the admission of selected surgical patients: a replicated study.it is well recognized that admission to hospital is a stressful experience for patients, and little attention is directed towards helping patients to adapt to hospitalization. this paper reports the replication of a descriptive study which explored the patient's welfare after the use of a patient-centred nursing approach designed to alleviate stress on admission to hospital. it also attempts to determine the patient's perception of the nurse during the implementation of the admission procedure, ...200193119
purification of alpha-fetoprotein from mouse amniotic fluid by gel-entrapped antibody filtration.a one-step immunospecific affinity chromatographic method for purification of mouse alpha-fetoprotein (afp) directly from amniotic fluid is described. the procedure employed a rabbit anti-afp immunoglobulin-g entrapped in a polyacrylamide gel matrix prepared as a gel slurry. the presence of impurities could not be demonstrated in the eluted fraction and the recovery of afp was approximately 26%. sufficient quantities of afp were readily purified for raising antibodies and for purity studies.197993130
[clinical evaluation of tumor scintigraphy with 99mtc-bleomycin. (part ii). combined studies of tumor scintigraphy with 99mtc-blm and 67ga-citrate, bone scintigraphy and angiography in bone and soft tissue tumors (author's transl)]. 200193151
hazards of intravenous diazoxide. 200193203
[alpha 1-antitrypsin deficiency in early childhood (author's transl)].alpha 1-antitrypsin inhibits various proteases and excessive proteolysis. if serum and tissue concentrations of this compound are low throughout longer periods of time due to deficient synthesis, - which is a dominantly inherited trait, - progressive pulmonary emphysema will develop in adults, and liver disease in more than 50% of the cases in infancy and early childhood. three subtypes can be distinguished: the heaptitis type, the intrahepatic hypoplasia of the bile duct system, and the cholang ...200193226
[clinical aspects, diagnosis and treatment of cancer of the large intestine]. 200193232
conjunctival transplantation as an alternative to keratoplasty.rehabilitation of the ocular surface is frequently desired following severe chemical and thermal injury. while keratoplasty, both lamellar and penetrating, has been the usual mode of therapy, chronic healing deficits and graft rejections as a result of heavy vascularization often lead to an unsatisfactory result. in unilateral injury, conjunctival transplantation from the opposite, uninvolved eye offers an alternative therapy which avoids both intraocular surgery and the introduction of immunolo ...200193258
[a new practice system for heart-lung resuscitation (dräger-laerdal]. 200193277
nucleoli visualized by silver staining combined with a new rna-specific fluorochrome.a technique for distinguishing nucleolar components by light microscopy is described. silver staining is used for localizing nuceolar-organizing regions. a new rna-specific fluorochrome, 4''-6-bis(2'-imidazolinyl-4'-5'h)-2-phenyl-4'-phenoxyindole, visualizes the rna-containing "partes fibrillares et granulares" of the nucleolus. both staining procedures can be combined to analyze nucleolar structure and function by light microscopy.200193328
severe skin pain after puva treatment.severe skin pain lasting one or two months occurred in 8 of 210 patients treated with puva. the pain started 4--8 weeks after the initial dose, mostly about one week after discontinuation of the treatment. it was a prickling, burning pain, usually coming in bouts and confined to limited areas "deep under the skin". in some respects the pain was related to itching, but the patients could easily distinguish between the two sensations. a variety of drugs was tried, but none had any noteworthy effec ...200193376
refsum's disease. eye manifestations in a patient treated with low phytol low phytanic acid diet.the cardinal eye symptoms of refsum's disease are night blindness, retinal pigmentary degeneration and constriction of the visual fields. similarities with or differences from retinitis pigmentosa are discussed. a 39-year-old male has had manifestations of refsum's disease from the age of 7 years and has been on a low phytol low phytanic acid diet for the last 13 years. peripheral ring scotomas were present. some reduction of the visual fields has been recorded, but only in the far periphery. th ...199993392
[orthograde fast axoplasmic transport in the optic pathway of alloxan induced diabetic albino rabbits. (preliminary report) (author's transl)]. 197993412
in vitro inhibition of prostaglandin synthesis by antithyroid drugs. 197993480
progress report on an evaluation of speech therapy for aphasia. 199993486
hereditary persistence of fetal haemoglobin (hpfh) and delta beta thalassaemia. 199993487
acute lindane poisoning. 199993506
symposium on uropathology. 197993566
abortive expression of the epstein-barr virus (ebv) cycle in a variety of ebv dna-containing cell lines, as reflected by nucleic acid hybridization in situ.a variety of epstein-barr virus (ebv) dna-containing cell lines have been tested for the expression of the ebv-associated antigens ebna (nuclear antigen), ea (early antigen), and vca (viral capsid antigen), and for the presence of cells containing disproportionate amounts of ebv dna. the antigen tests utilized immunofluorescence and 125i-labelled antibodies combined with autoradiography. ebv-dna was detected by in situ hybridization with 3h-labelled ebv rna complementary to p3hr-1 ebv dna (p-ebv ...197993584
alpha-fetoprotein inhibits antibody binding to acetylcholine receptor. significance for myasthenia gravis and other autoimmune diseases. 197993589
fine structural observations of calcium storage in human dental pulp cells in primary culture.primary culture of explants of human dental pulp tissue allows the study of the cytophysiology and differentiation of the cultured cells over a two-week period. the distribution of calcium was found in two different experimental conditions : with and without a calcium loading, by mean of a lead technique checked by microprobe analysis. the existence of two cell populations was revealed. intra-mitochondrial ring-like granules characterize type 1 cells when overloaded, while a strong calcium stora ...197993605
the prognosis of intraventricular hemorrhage.a series of 40 patients with blood in the cerebral ventricular system demonstrated by computed tomography (ct) is presented. overall prognosis was found to be better than expected from the literature. nearly half of the patients are still alive; 12 of the 40 patients in this study had no significant residual disability. the results suggest that the rupture into the ventricular system by itself is of minor importance. however the clinical condition of the patient on admission, site and origin of ...199993626
differentiation of normal pressure hydrocephalus and cerebral atrophy by computed tomography and spinal infusion test.the diagnostic value of computed tomography (ct) and spinal infusion test (sit) was investigated in 27 patients with normal pressure hydrocephalus (nph) and 35 patients with cerebral atrophy. the most consistent ct finding of nph was dilatation of the temporal horns, that of cerebral atrophy widening of the convexity sulci. however, 43% of patients with cerebral atrophy demonstrated no cortical atrophy. the sit showed an excellent relation with isotope cisternography and continuous intracranial ...199993629
[studies on elastase in pancreatic diseases (author's transl)]. 199993654
[problems in modern syphilis diagnosis]. 199993688
location of bladder preganglionic neurons within the sacral parasympathetic nucleus of the cat.sacral parasympathetic preganglionic neurons innervating the urinary bladder were labelled by applying horseradish peroxidase (hrp) to branches of the pelvic nerve at the neck of the bladder. bladder preganglionic cells were located primarily in the intermediolateral grey matter of sacral cord segments 1, 2 and 3 and extended from the ventral end of the central canal to the inferior margin of the dorsal horn. dendrites extended into the dorsolateral funiculus, toward the lateral edge of the dors ...197993725
problems associated with prolonged wear soft contact lenses.complications of prolonged wearing of soft contact lenses are corneal infection, peripheral vascularization, giant papillary conjunctivitis and allergy, sterile ulcers, corneal warping, lens infection, protein and calcium deposits, lens fragility, and problems with disinfecting solutions. further long-term studies are needed to compare the safety of prolonged wear soft contact lenses with the safety of intraocular lenses, on which long-term studies are currently being done.197993736
prostatism. i. the correlation between symptoms, cystometric and urodynamic findings.one hundred and seven consecutive patients referred with symptoms of bladder outlet obstruction were studied using cystometry and combined pressure-flow-electromyographic investigation. the symptoms of infravesical obstruction were not statistically significantly correlated to the hydrodynamic documentation of increased bladder outlet resistance as judged by maximum flow rate and the calculated urethral resistance. irritative symptoms such as frequency, nocturia, urgency and urgeincontinence wer ...199993780
intra-operative frozen section technique for pituitary adenomas.orange g-hematoxylin stains performed on frozen sections from the sella turcica had a diagnostic accuracy of over 90% when compared to permanent sections on the same tissue. this technique allows the pathologist to make an intra-operative contribution to the establishment of tumor margins in the selective removal of pituitary adenomas.199993851
myelin basic protein treatment of experimental allergic encephalomyelitis in monkeys.treatment of experimental allergic encephalomyelitis (eae) in two strains of monkeys with large amounts of myelin basic basic protein (bp) fails unless an adjunct is also used. in both strains the adjunct by itself is more effective than bp by itself, but in the one strain which could be investigated sufficiently, the combination can be made almost totally effective in reversing eae. the adjunct varies with the strain of monkey, an antibiotic in macaca mulatta and a steroid in macaca fasciculari ...197993874
analysis of rna-binding proteins of cryptobiotic gastrula of artemia saline [proceedings]. 199993910
semicarbazide-sensitive amine oxidase in rat aorta: a plasma-membrane enzyme [proceedings]. 197993954
effects of bleomycin and irradiation on euoxic and hypoxic cells. 199994049
study of effectiveness of bleomycin in rat brain tumor model intravenously and intracerebrally. 197994056
effects of tamoxifen on the binding and metabolism of testosterone by human prostatic tissue and plasma in vitro.the in-vitro metabolism of testosterone in benign and malignant prostatic tissue was examined and distinct quantitative differences between the two types of specimens were observed. the major metabolite of testosterone in the hyperplastic prostate was 5 alpha-dihydrotestosterone and a high 3 alpha(beta)-hydroxysteroid dehydrogenase activity was also detected. in the malignant tissue, 5 alpha-reductase activity was considerably reduced and there was little or no androstanediol formed; the 17 beta ...197994084
[cases of leukemoid plasma cell reaction]. 199994128
[clinical and biochemical contributions on the effect of maprotiline and clomipramine in depressive states (preliminary observation)].this study has been conducted on 17 patients suffering from neurotic and psychotic depressions, who had not received a pharmacological antidepressive therapy since at least 1 month. 6 patients suffering from psychotic depression were treated with 100 mg clomipramine i.v. daily for 20 days; 11 patients, 7 of whom suffered from psychotic depression and 4 from neurotic depression, were treated with 150 mg maprotiline i.v. daily for 20 days. in both groups the therapy has been continued orally. in ...197994169
[alpha fetoprotein and prenatal detection of malformations of the neural tube]. 199994172
a double-blind trial of synthetic salmon calcitonin in the treatment of acute pancreatitis.a multicenter randomized double-blind trial on the use of synthetic salmon calcitonin (sct) was carried out in 94 patients with acute pancreatitis. in addition to strict standard treatment--without aprotinin, atropine, or antacids--50 patients received daily 3 x 20 micrograms = 300 mrcu sct intravenously and 44 patients received placebo for 6 days. mortality rate was not influenced, overall mortality being 5.3%. the number of patients without pain and with normalized serum amylase on a given day ...199994176
carbon monoxide pollution in jakarta, indonesia. 199994183
erythemal and pigmentary phototest reactions in polymorphic light eruptions.the erythemal and pigmentary skin reactions in 110 patients with chronic polymorphic light eruptions (pmle) and in 154 control persons were investigated by phototesting with a medium pressure mercury lamp. recording the erythemal threshold (med) at 2-h intervals for up to 24 h after irradition disclosed no differences between pmle patients and controls. there was, however, a tendency for the erythemal reaction to subside more slowly in the pmle patients; this tendency reached a statistically ver ...199994208
cyclic amp and psoriasis once more.imbalanced cyclic nucleotides are implicated as an underlying pathogenetic mechanism in psoriasis, but conflicting data on the levels of camp in psoriatic tissue have been obtained by different laboratories. using heat separation and a competitive protein binding camp assay, a noticeably decreased epidermal level of camp was detected in newly formed guttate lesions in 10 patients with psoriasis (involved: 4.32 +/- 1.06 pmol/mg dry weight mean +/- s.e.m.). uninvolved: 7.97 +/- 1.63 pmol/mg dry we ...197994212
induction of delayed-type sensitivity to leishmania parasite in a case of leishmaniasis cutanea diffusa with bcg and cord-factor (trehalose-6-6' dimycolate).the delayed hypersensitivity against the leishmania parasite was restored to a patient who had suffered from diffuse cutaneous leishmaniasis (dcl) for 26 years, by the application of an ointment containing heat-killed and lyophilized bcg and cord-factor (trehalose-6-6'-dimycolate) after stripping the affected and adjacent areas with scotch-tape.197994221
the mast cell in allergic disorders. 200094232
characterization of 40,000- and 25,000-dalton intermediate precursors to rauscher murine leukemia virus gag gene products.under steady-state labeling conditions, rauscher murine leukemia virus-infected nih swiss mouse cells contain at least three major polyproteins derived from the viral gag gene. they have molecular weights of 65,000, 40,000, and 25,000. they have been termed ppr65gag, pr40gag, and ppr25gag. ppr65gag has been shown by a number of laboratories to be composed of all four core proteins (p15, pp12, p30, and p10). in this paper, pr40gag was found to contain p30 and p10 antigenic determinants and peptid ...197994357
disopyramide plasma and myocardial tissue concentrations as they relate to antiarrhythmic activity.antiarrhythmic concentrations of disopyramide in canine plasma and myocardium were determined by gas chromatography. ventricular tachycardia was incuded in anesthetized dogs by the intravenous administration of ouabain. disopyramide phosphate was then administered by a two-stage continuous infusion method. a rapid infusion of disopyramide (9.08 mg/kg/hr) was administered for 30 min, followed by a slow infusion (2.18 mg/kg/hr) to maintain steady-state plasma levels of 1.98-2.21, mean +/- sem = 2. ...197994410
effects of etafenone and antiarrhythmic drugs on na and ca channels of guinea pig atrial muscle.since ca-mediated electrophysiological phenomena seem to be important in the generation of various arrhythmias, we quantitatively compared the effects of quinidine, disopyramide, procainamide, lidocaine, propranolol, and etafenone, a new coronary vasodilator with antiarrhythmic properties, on na and ca channels in normal and depolarized guinea pig atria. the maximum rate of rise of the normal action potential and the amplitude of the depolarized, ca-mediated action potential were measured to exa ...197994412
[effect of cytochrome c, sulnate and contrical on a change in the blood coagulating system and fibrinolysis during blood flow recovery in ischemic extremities]. 197994430
beta thromboglobulin and glycosylated haemoglobin in diabetes mellitus.no correlation has been demonstrated between the elevated levels of plasma beta-thromboglobulin and glycosylated haemoglobin found in a group of 97 diabetic patients. the abnormality in diabetic platelets which is reflected by beta-thromboglobulin levels may not therefore be a direct result of poor metabolic control. the highest levels of beta-thromboglobulin were found in those patients with a raised blood urea. glycosylated haemoglobin levels correlated with prevailing blood glucose and with t ...200094458
[comparative examinations of high-molecular maternal serum protein bodies during pregnancy--a contribution to biochemical pregnancy control (author's transl)].the maternal serum concentrations of beta 1 sp 1, igm and alpha 2-macroglobulin were determined in relation to the gestation age, using the simple radial immunodiffusion method in 102 non-pathologic pregnancies and 35 pregnancies involving risk factors. to assess the clinical relevance of these determinations, we examined to what extent the changes in concentration of beta 1 sp 1 igm and alpha 2-macroglobulin would permit a prognostically useful conclusion on the placenta function and foetal con ...200094488
azure b-eosin staining of blood cells: the effects of variation in stain formulation and staining technique on stain performance.a quantitative study of azure b-eosin-stained blood cells is reported. the effects of variation in stain formulation and staining technique on the binding of azure b and eosin by acidophilic, basophilic and neutrophilic substrates were measured by scanning microdensitometry. the variables considered were stain concentration (the azure b-eosin concentration ratio was constant), azure b concentration (at constant eosin concentration), eosin concentration (at constant azure b concentration), staini ...200094523
the rate of movement of [3h]-water and [14c]-dextran into the gingival sulcus of the rabbit. 197994543
[localization of sacral spinal neurons innervating the perineal muscles--a hrp study in dog (author's transl)]. 197994556
[therapeutic effectiveness and tolerability of p-isobutylphenylpropionate of lysine, in parenteral administration, in subjects with hyperalgic forms of rheumatic arthropathy]. 200094559
effects of hydroxyurea on crithidia fasciculata.hydroxyurea (hu) inhibits increase in cell number in cultures of crithidia fasciculata. complete inhibition is produced by 8 mm and higher concentrations. if hu is not removed, population growth resumes in 45-50 h; if hu is removed, partially synchronous growth occurs through 2 cycles. during hu inhibition, the rate of dna synthesis is reduced to 1% of that in exponentially growing cultures; protein and rna syntheses continue at slightly reduced rates. mean cell size and protein and rna contents ...200094609
do overlapping genes violate molecular biology and the theory of evolution? 200094642
a thymus-independent igg response against dextran b512 can be induced in c57bl but not in cba mice, even though both strains possess a vhdex gene.cba and c57bl mice both possess a vhdex gene coding for antibodies against the alpha 1-6 epitope of dextran b512. after immunization with dextran, cba mice produce igm plaque-forming cells (pfc) only, which show regular cyclical fluctuations. the second pfc peak disappeared after injection of dextranase, indicating that it is antigen-dependent. the anti-dextran response in c57bl mice is characterized by only one igm peak, followed 1 day later by an igg peak that may exceed the igm response by a ...200094695
keratinization of the conjunctiva.keratinization of the tarsal conjunctiva in an eye with adequate tears occurs following a number of conditions, including irritation and sensitivity to topical medications, stevens-johnson syndrome, radiation to the lid, and occasionally from unknown causes. the keratinized cells produce an epithelial keratitis with subsequent vascularization of the cornea. the morphogenesis of this condition is discussed, along with therapy including mucous membrane grafts and freezing of the tissue.200094716
[characteristics of immunoglobulin dynamics and absorption in newborn calves].a study on protein dynamics in calf blood serum from the time of birth to age of 60 days was carried out by use of electrophoresis on 1% agar gel, immunodiffusion and immunoelectrophoresis with rabbit immune serum against cattle blood serum, colostrum whey and pure nu-globulin. investigations were performed on the 4th and 24th hour, and on the 3rd, 6th, 8th, 10th, 15th, 20th, 30th, 45th and 60th day after birth. resorption of colostral gamma globulins, applied intravenously and orally in the for ...197994718
new surgical management in the cleft palate repair and its histological aspects. 197994731
frontiers of quantitative cytochemistry: a review of recent developments and potentials.this article attempts to describe the current state of quantitative cytochemical methods and to point out areas where, in the author's opinion, the greatest progress is either being made or can be expected. nearly 300 references to the current literature are cited.200094776
[the mechanism of thrombolysis with streptokinase]. 200194883
induction of monoclonal antibody synthesis in malignant human b cells by polyclonal b cell activators. relationship between b cell subsets and prognosis. 197994897
analytical separation of bleomycin. 200194911
rapid gas chromatographic method for the determination of kepone in the eel. 200194914
study of the interaction between phosphorylase and hydrophobic groups by means of affinity electrophoresis.a homologous series of water-soluble alkyl-dextrans varying in the length of their hydrocarbon side-chain [-nh-(ch2)n-ch3; n = 1-5] were synthesized. when alkyl-dextrans were entrapped in polyacrylamide gel, the electrophoretic mobility of phosphorylase was retarded by hydrophobic interaction between phosphorylase and the immobilized alkyl groups. the dissociation constants of rabbit brain phosphorylase, rabbit skeletal muscle phosphorylase a and b and potato glycogen and starch phosphorylases w ...197994915
[indoleamine precursors in depression (author's transl)].tryptophan and 5-hydroxytryptophan have now been extensively investigated in affective disorders. there is now very good evidence that tryptophan increases the antidepressant activity of monoamine oxidase inhibitors. the antidepressant activity of tryptophan and 5-hydroxytryptophan has also been the subject of numerous investigations. there is evidence that patients with decreased cerebrospinal fluid concentration of 5-hydroxyindoleacetic acid respond particularly favourably to this treatment. t ...200195009
presentation of the pennsylvania dental association award to dr. laurence l. lathrop. 200195043
[saforide]. 200195064
[dangers of rapid digitalization].on the patients with moderate and severe heart insufficiency haemodynamic, clinical and electrocardiographic examinations were carried out. after the application of digitoxin at the beginning in the majority of cases no favourable effects on clinical and haemodynamic findings could be proved. in 2 patients with cor pulmonale even a drastic deterioration with increase of the pulmonary pressure and formation of a pulmonary oedema developed. the temporary analysis of the systole and the estimation ...200195071
the keraton. a biological unit of the epidermis.the term keraton is proposed to denote that specific subpopulation of epidermal cells that matures to form epidermis and horny layer exclusive of other functional units within the epidermis such as melanocytes, acrosyringium, acrotrichium, langerhans' cells, and nerves.200195081
demonstration of a murine cell surface component with affinity for exogenous beta 2-microglobulin.murine and human beta 2-microglobulin (beta 2m) bind to various types of mouse cells. the binding is saturable and displays a single association constant of about 1 x 10(9) liter/mol. the binding of beta 2m to splenocytes was not affected by a variety of metabolic inhibitors but was temperature-dependent. it is suggested that the beta 2m "receptor" exhibits a temperature-dependent conformational change since the "receptor", whether integrated into the membrane or solubilized by the detergent tri ...197995108
[use of audiovisual equipment in the department of dentistry in japanese universities (1)]. 200195110
subclassification of murine t cells by computerized microphotometric analysis.splenocytes separated by physical means and classified as t cells bay immunologic tests and computerized microphotometric analysis are differentiated into subgroups by analysis of the distribution patterns of feulgen-positive nuclear dna. in like fashion t cells obtained as purified preparations after separation on a nylon column, and accepted as t cells by micromorphometric analysis were subjected to further computerized morphometric analysis of nuclear dna to form subgroups of cells. in each c ...200195181
normally functioning inhibited pacemaker concomitant with vertebral nerve stimulator.electromagnetic inference is a recognized difficulty in concomitant cardiac pacing and nerve stimulation. a case is reported in which a vertebral nerve stimulator was implanted, with a transmitter antenna distal to the right nipple. six months later, intermittent s-a block with adams-stokes attacks urgently necessitated cardiac pacing. the ecg lead ii showed nerve stimulator potentials of 0.75 mv. intracardiac electrogram with unipolar electrode registered potential of 0.25 mv, but with a bipola ...200195228
aggression in humans correlates with cerebrospinal fluid amine metabolites.cerebrospinal fluid of the major central metabolites of serotonin (5ht), norepinephrine (ne), and dopamine (da)--5-hydroxyindoleacetic acid (5hiaa), 3-methoxy-4-hydroxy=phenylglycol (mhpg), and homovanillic acid (hva), respectively--were studied in a group of 26 age-similar military men with no history of major psychiatric illness, but with various personality disorders and difficulties adjusting to military life. independently scored history of aggressive behavior showed a significant negative ...200195232
[psychological diagnosis problems in children between 0 and 3 years of age]. 200195256
gas pocket causing pacemaker malfunction.pacemaker malfunction was attributed to the increase in impedance to current flow caused by a pocket of air separating the anodal contact plate of a unipolar generator from the overlying skin. lack of capture was noted 20 hours after implantation. the malfunction was permanently corrected by bedside aspiration of the gas with a sterile syringe.200195278
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