Publications

[clinico-immunologic characteristics of opisthorchiasis in children living in a natural focus of the disease].		2009	2786621
[a trial of suppressing secondary hyperparathyroidism by oral high dose therapy of 1, 25-dihydroxyvitamin d3].	we reported a successful treatment of secondary hyperparathyroidism by intermittent oral administration of high dose of 1, 25 dihydroxycholecalciferol [1.25-(oh)2d3] in three patients on maintenance hemodialysis. dialysis durations were 4 months in case 1, 6.5 years in case 2 and 12.5 years in case 3. the levels of c-pth ranged from 4.7 ng/ml to 94.2 ng/ml. 1, 25-(oh)2d3 in dosages up to 8.0 micrograms was given once a week just after hemodialysis. before the administration and after 48 hours, s ...	2009	2787433
an assessment guide for community health nurses.	an assessment tool based on the omaha classification system broadens the focus of nursing diagnosis to encompass the cultural and sociological aspects of each area of patient assessment.	2010	2793509
intraspinal course of descending serotoninergic pathways innervating the rodent dorsal horn and lamina x.	although numerous studies have discussed serotoninergic pathways projecting from the brainstem to the spinal cord, the intraspinal course of these descending axons remains a matter of debate. one of the difficulties with traditional immunohistochemical methods is that the interpretation of results has been subjective. we have therefore employed a computer-assisted image-processing system to provide objective measurements of serotonin immuno-reactivity within the rodent dorsal horn and lamina x c ...	1989	2794118
purification and characterization of dihydropyrimidine dehydrogenase from pig liver.	dihydropyrimidine dehydrogenase was isolated from cytosolic pig liver extracts and purified 3100-fold to apparent homogeneity. purification made use of ammonium sulfate fractionation, precipitation with acetic acid and chromatography on deae-cellulose and 2',5'-adp-sepharose with 28% recovery of total activity. the native enzyme has a molecular mass of 206 kda and is apparently composed of two similar, if not identical, subunits. proteolytic cleavage reveals two fragments with apparent molecular ...	1989	2806259
3-sulfonyl-1-carba-1-dethiacephems.	the stability of the 1-carba-1-dethiacephalosporin framework has allowed the synthesis of a range of 3-sulfonyl-1-carba-1-dethiacephems unavailable for a variety of reasons in the cephem arena. the known p-nitrobenzyl 7 beta-(phenoxyacetamido)-3-[[(trifluoromethyl)sulfonyl]oxy]-1-carba -1- dethia-3-cephem-4-carboxylate served as a precursor to this series of compounds. displacement of the enol triflate with various sulfinates in acetonitrile or dmf and deprotection of the intermediates led to 7 ...	1989	2810332
"a few bad apples?".		2009	2812134
"a few bad apples?".		2009	2812134
[intraoperative monitoring of cerebral function and carotid hemodynamics during carotid endarterectomy].	the authors investigated the hemodynamics and monitored the cerebral function to perform the carotid endarterectomy (cea) safely. the hemodynamics were investigated by measurements of carotid arterial blood flow by an electromagnetic flow meter before and after cea. and a doppler flow meter applied directly to the carotid arteries to analyze the flow parameters such as peak frequencies (pf), mean frequencies (mf), mode frequencies (mo f) and % window. we used routinely our specially designed shu ...	2009	2812257
[intraoperative monitoring of cerebral function and carotid hemodynamics during carotid endarterectomy].	the authors investigated the hemodynamics and monitored the cerebral function to perform the carotid endarterectomy (cea) safely. the hemodynamics were investigated by measurements of carotid arterial blood flow by an electromagnetic flow meter before and after cea. and a doppler flow meter applied directly to the carotid arteries to analyze the flow parameters such as peak frequencies (pf), mean frequencies (mf), mode frequencies (mo f) and % window. we used routinely our specially designed shu ...	2009	2812257
smoking and other tobacco use.		1989	2815598
smoking and other tobacco use.		1989	2815598
on the estimation of pulmonary capillary pressure from arterial occlusion.	we have attempted to evaluate some approaches for estimating pulmonary capillary pressure from the transient pressure data obtained from the tip of the swanz-ganz catheter after inflation of the balloon. to this end experiments were carried out in anesthetized dogs in which pulmonary vasoconstriction was induced by infusion of histamine, serotonin, or norepinephrine or by hypoxia. in a group of closed chest dogs, the time course for the fall in the catheter tip pressure toward the wedge pressure ...	1989	2817586
[remote (2-3 years) results in patients with pulmonary tuberculosis treated in operational conditions in combination with sinerdol-eh].		2010	2825331
rings, dicentrics, and telomeric association in histiocytomas.	we report clonal karyotypic abnormalities in six of 12 cytogenetically investigated malignant fibrous histiocytomas. four of eight tumors of the pleomorphic subtype had complex clonal chromosome aberrations, including ring chromosomes, dicentric chromosomes, and/or telomeric associations. no common characteristic aberration could be distinguished. two of four myxoid tumors had clonal changes: one had one to two ring chromosomes and an extra chromosome #2; another had a supernumerary ring chromos ...	2010	2825965
neurothermography.	neurothermography is a new, clinically useful method of detecting autonomic sympathetic peripheral nerve dysfunction. body symmetry of the skin temperature as maintained by symmetrically functional peripheral nerves is the key to detecting a normal state. persistent 1 degree c temperature asymmetry in the pattern of a peripheral nerve (thermatome) is a highly reliable method of detecting autonomic peripheral nerve disorder.	2010	2845550
age-dependent changes in murine protein kinase and protease enzymes.	hormone responsiveness is mediated by signal transduction mechanisms involving second messengers, such as camp and ca2+, which regulate reversible changes in the phosphorylation state of proteins. during senescence individuals frequently exhibit a diminished responsiveness to hormones. we examined changes in enzymes involved in protein phosphorylation reactions that might account for this decreased adaptiveness in old mice, and observed the following post-maturational changes: (1) camp-dependent ...	2010	2852280
development of gentamicin resistance in gram-negative bacteria in czechoslovakia and correlation with its usage.	widespread use of gentamicin in czechoslovakia began in 1975 when it became more available, although its use remained restricted until 1986. starting in 1980 a remarkable increase in gentamicin resistance was observed in pseudomonas aeruginosa, klebsiella, enterobacter and several proteus species, especially proteus rettgeri. a large proportion of gentamicin-resistant strains came from the urine of hospitalized patients. in spite of infection control measures and restrictive antibiotic policy, g ...	1988	2854783
ontogeny of mhc-linked, t cell-mediated suppression is regulated by the t cell genotype.	regulation of t cell effector functions by major histocompatibility complex (mhc) gene products has been extensively researched. investigations in this area have established several important concepts of immunobiology. first, genes within the i-region of the mhc profoundly affect development of immune responses through their effects on cell-cell interactions. in the course of analyzing antigen-induced t cell activation, investigators identified specific ir-genes by demonstrating that certain str ...	2010	2855403
characterization of dimethylnitrosamine-induced focal and nodular lesions in the livers of newborn mice.	newborn swiss-webster mice were given an intraperitoneal injection of 25 micrograms of dimethylnitrosamine. at weaning they began receiving 0.05% phenobarbital in the drinking water to promote the lesions for the term of the study. preneoplastic foci and hyperplastic nodules were identified histologically by two markers, resistance to exogenous iron accumulation and an increase in gamma-glutamyltranspeptidase activity. at 8, 12, and 16 weeks of age, livers of affected male mice exhibited 12, 18, ...	2010	2863866
distribution and morphology of somatostatin cells.		2010	2863943
pain, prostaglandins, and food lipids. influences of dietary polyunsaturated fatty acids on eicosanoid synthesis and effects.		2007	2870709
activities in nursing ethics: local, national, international.		2010	2876421
mitochondrial protein import: involvement of the mature part of a cleavable precursor protein in the binding to receptor sites.	the precursor of f0-atpase subunit 9 was bound to mitochondria in the absence of a mitochondrial membrane potential (delta psi). binding was mediated by a protease-sensitive component on the mitochondrial surface. when delta psi was reestablished, bound precursor was directly imported without prior release from the mitochondrial membranes. a chimaeric protein consisting of the complete subunit 9 precursor fused to cytosolic dihydrofolate reductase (dhfr) was also specifically bound to mitochondr ...	2010	2892669
involvement of prostaglandins in histamine-induced fluid and electrolyte secretion by rat colon.	histamine increased the transmural potential difference across rat colon in-vivo and induced a net secretion of fluid. both effects were inhibited by indomethacin. histamine increased the potential difference and short-circuit current, and reduced tissue resistance in colonic sheets in-vitro. this response was reduced in the absence of chloride in the bathing medium or in the presence of serosal frusemide, suggesting that histamine stimulated electrogenic chloride secretion by the colon. the ris ...	1988	2897440
isolation and mapping of a polymorphic dna sequence (pynz32) on chromosome 4p [d4s125].		1988	2897672
reduced hypothalamic somatostatin and neuropeptide y concentrations in the spontaneously-diabetic chinese hamster.	hypothalamic concentrations of six regulatory peptides having central effects on appetite and/or glucoregulation were measured by radioimmunoassay in spontaneously-diabetic chinese hamsters and in age- and sex-matched non-diabetic control animals. in the diabetic hamsters, hypothalamic concentrations of somatostatin and neuropeptide y were significantly reduced by 25-30% below controls. none of the other four peptides examined (bombesin, galanin, neurotensin and vasoactive intestinal peptide) di ...	2010	2905691
cigarette smoking and down syndrome.	a matched case-control study of 100 mothers of down syndrome children, 100 mothers of children with other defects (defect controls), and 100 mothers of children with no defects (normal controls) was carried out. all infants were born in upstate new york in 1980 and 1981. matching was very close on maternal age for the normal controls but not for the defect controls. the risk ratios for the association of cigarette smoking around the time of conception with down syndrome was 0.58 (90% confidence ...	2010	2934980
fun and games in urology.		2010	2938562
effect of atrial peptide on collecting duct function.	1. the effects of synthetic rat atrial natriuretic peptides (anp) on diffusional 22na+, 36cl- and tritiated water (tho) permeability of in vitro microperfused rat papillary collecting ducts and the effect in vivo of anp on stop-flow sodium concentrations in the terminal segment of rabbit nephrons were studied. 2. the addition of 4 x 10(-8) or 4 x 10(-7) mol/l anp to the medium or perfusion solution did not alter diffusional 22na+ or 36cl- permeability of microperfused rat papillary collecting du ...	1988	2976327
technique for measurement of one-dimensional instantaneous ablation velocity.	an oscillating mirror scanned a he-ne laser beam along the length of a thin rod while the rod was ablated by an argon laser beam. the shadow of the scanning beam on an image plane provides a picture of the instantaneous ablation velocity of the rod. this configuration provides a unique method for investigating one-dimensional ablation.	2010	2976448
atrophy of the left hepatic lobe caused by a cholangiocarcinoma.		2010	2982248
in vivo and in vitro studies of urinary concentrating ability in potassium-depleted rabbits.	the factors responsible for the urinary concentrating defect associated with the potassium-depleted (kd) state are uncertain. the present studies were designed to, first, determine whether a urinary concentrating defect exists in potassium-depleted rabbits and, second, to use the technique of in vitro perfusion to evaluate directly the antidiuretic hormone (adh) responsiveness of cortical collecting tubules (cct) in this setting. feeding female new zealand white rabbits a potassium-deficient die ...	1985	2993361
ouabain-resistant mutants of chinese hamster ovary cells are not directly affected in na+, k+-atpase.	the nature of biochemical lesions in a number of independent single-step ouabain-resistant (ouar) mutants of chinese hamster ovary cells has been examined. the cellular uptake of 86rb in the mutant cells was found to be resistant to inhibition by ouabain and correlated with the degree of resistance of the mutants to the drug. however, the plasma membrane na+, k+-atpase from all five of the ouar mutants examined showed similar sensitivity to inhibition by ouabain as seen for the enzyme from the p ...	2010	3016917
t-lymphocytes subpopulation before and after surgical removal of hepatocellular carcinoma.	this study included 16 histologically confirmed hepato-cellular carcinoma (hcc) patients. at the same time, 32 normal healthy individuals and 20 asymptomatic hepatitis b surface antigen (hbsag) carriers were served as control groups. the study disclosed that t cells, okt4 cells and the ratio of okt4 cells/okt8 cells in peripheral venous blood of hcc patients before surgery were lower than that of either normal control or asymptomatic hbsag carriers. the difference was statistically significant. ...	2010	3028718
t-lymphocytes subpopulation before and after surgical removal of hepatocellular carcinoma.	this study included 16 histologically confirmed hepato-cellular carcinoma (hcc) patients. at the same time, 32 normal healthy individuals and 20 asymptomatic hepatitis b surface antigen (hbsag) carriers were served as control groups. the study disclosed that t cells, okt4 cells and the ratio of okt4 cells/okt8 cells in peripheral venous blood of hcc patients before surgery were lower than that of either normal control or asymptomatic hbsag carriers. the difference was statistically significant. ...	2010	3028718
identification of porins in outer membrane of proteus, morganella, and providencia spp. and their role in outer membrane permeation of beta-lactams.	proteus mirabilis, proteus vulgaris, morganella morganii, providencia rettgeri, and providencia alcalifaciens, which were once classified into the same genus, proteus, were studied. cefoxitin-resistant mutants from these species were isolated, and it was confirmed that the resistance was attributed to the lack of an outer membrane protein, resulting in a significant decrease in the penetration of hydrophilic cephalosporins through the outer membrane. comparison of the mutant strains with their p ...	1987	3034144
[ultrasonics and directional doppler. study of superficial phlebitis of the lower extremities].	the objective of the study was to evaluate the usefulness of ultrasonic methods: ultrasonography and doppler c.w. in the diagnosis of superficial varicose phlebitis. especially, measurement of the venous pressure (v.p.) at the posterior tibial (p.t.) and the greater saphenous vein (g.s.v.) in clino and orthostatism, have proved to be useful. in ten cases, one patient with a varicose in the thigh, was also found to have a femoral vein thrombosis secondary to a deep thrombus entering the junction. ...	2011	3043475
[the usefulness of projective methods in the diagnosis of schizophrenia].		2011	3043507
tolerance of pelvic normal tissues to hyperfractionated radiation therapy: results of protocol 83-08 of the radiation therapy oncology group.	a prospective, centrally randomized phase i/ii trial of hyperfractionation in definitive radiation therapy for locally advanced squamous and transitional cell carcinoma of the bladder was conducted by the radiation therapy oncology group (rtog) from april 1983 through june 1986. patients with t3-4 and t2 n+ (ajc) histologically-confirmed cancer of the bladder received twice daily radiation therapy with 1.2 gy per fraction and a minimum of 4 hr between fractions. all patients received a whole pel ...	1988	3058657
severe medical illness complicating cesarean section.	the care of the perioperative cesarean birth patient who has serious medical illnesses has changed in the past decade. the increasing sophistication of monitoring has allowed the obstetrician and anesthesiologist better to modify certain physiologic parameters that are important in the care of the patient whose physiology has been altered by surgery or disease. as an increasing segment of the obstetric population becomes older, and with better survival of medical diseases, the profession as a wh ...	2011	3067176
[use of photosensitizing preparations in the treatment of cancer of the orl organs].		2011	3067440
the 'bn2' gene, a regulator for the onset of chromosome condensation.		2011	3067728
promoter selectivity of prokaryotic rna polymerases.		2011	3076288
in vitro evaluation of a-56619 (difloxacin) and a-56620: new aryl-fluoroquinolones.	the in vitro antibacterial potencies of a-56619 and a-56620, two new aryl-fluoroquinolones, were compared with the potency of norfloxacin against a broad spectrum of organisms. cefotaxime, aztreonam, piperacillin, imipenem, penicillin, and gentamicin were also tested for reference purposes. the mics required to inhibit at least 90% of the strains tested ranged from 0.25 to 4 micrograms/ml for a-56619 and from 0.06 to 0.5 microgram/ml for a-56620 for members of the enterobacteriaceae. a-56619 was ...	1986	3087274
in vitro activity of aztreonam against gram negative bacteria from clinical specimens and its comparison with other commonly used antibiotics.	a total of 755 gram negative bacteria isolated from clinical specimens were tested against aztreonam by the disc agar diffusion test. the strains of bacteria used in this study consisted of escherichia coli (314), enterobacter aerogenes (30), e. agglomerans (7), e. cloacae, (39), citrobacter diversus (9), c. freundii (13), hafnia alvei (3), acinetobacter calcoaceticus (10), klebsiella oxytoca (6), k. ozaenae (5), k. pneumoniae (107), morganella morganii (3), moraxella sp. (10), pasteurella multo ...	1986	3088346
microbiological basis for the use of fosfomycin trometamol as single-dose therapy for simple cystitis.	fosfomycin trometamol (fot), a new soluble salt of fosfomycin, was developed especially for single-dose treatment in uncomplicated urinary tract infections. in this study, the minimum inhibitory concentrations (mics) of fot were measured both in nutrient broth and human urine and compared with calcium fosfomycin, pipemidic acid and cotrimoxazole. a total of 300 bacterial strains of different species from recent urinary infections were studied. staphylococcus aureus showed the lowest mic (0.38 mi ...	1986	3094965
accessory molecules in t lymphocyte activation.	the currently accepted hypothesis used to explain the role of lyt-2 and l3t4 in t cell activation proposes how these molecules interact with class i and ii major histocompatibility complex molecules, respectively, on the antigen-presenting or target cell, to increase the avidity of binding of the antigen-specific t cell receptor. this has been tested using two antigen-specific, class ii-restricted t cell clones expressing both lyt- and l3t4. inhibition of function was observed only with monoclon ...	2011	3106237
[regulation of milk intake in young ruminants].	we studied the influence of the three main nutritive components of milk - saccharides, fat and amino acids - on milk intake in suckling lambs and on the role of insulin as a key metabolic hormone for the regulation of milk intake. the intake was slowed down after p.o. administration of milk fat (p less than 0.05), after i. v. administration of methionine (p less than 0.001) and after p. o. administration of glucose, lactose (p less than 0.01, p less than 0.001) and sorbitol (p less than 0.001). ...	1987	3109104
acute gangrene of the scrotum and penis in four hematologic patients. the usefulness of hyperbaric oxygen therapy in one case.	we describe four cases of fournier's gangrene complicating the postchemotherapy aplastic phase (polymorphonuclear cells [pmn] less than 500/microliter) in three patients with acute leukemia and one patient with non-hodgkin's lymphoma. blood and local cultures from two patients contained pseudomonas aeruginosa, and local cultures from another patient grew both p. aeruginosa and proteus rettgeri. early recognition and aggressive antibiotic and surgical treatment with granulocyte recovery were fund ...	1987	3113713
the correlates of research success.	a survey was carried out of the undergraduate backgrounds and research achievements of 885 (94.1%) of all 940 medically qualified professors and readers in medical faculties in the united kingdom. a total of 217 (24.5%) of the graduates in these senior academic positions had graduated from oxford or cambridge and 137 (15.5%) had an intercalated bsc. the corresponding figures for a control group matched for sex and date of graduation were 118 (13.3%) for oxford and cambridge (academic to control ...	2011	3115391
acute phase reaction following chemotherapy.		2011	3118119
deficiency of eosinophil peroxidase detected by automated cytochemistry.		2011	3122494
[a case of recurrent epipharyngeal cancer showing complete disappearance following suppository administration of tegafur (sunfural rectal capsules)].	a 55-year-old woman was diagnosed as having epipharyngeal cancer, characterized by t2n1m0 and poorly differentiated squamous cell carcinoma. she was treated by radiotherapy (primary site: 65 gy, neck: 75 gy) and the tumor completely disappeared. however, 4 months later, the tumor recurred in the epipharynx. tegafur in the form of a suppository (sunfural rectal capsules, 750 mg) was given once a day. during the course of epipharyngoscopic follow-up the tumor almost totally disappeared at a dose o ...	2011	3122667
[primary leiomyosarcoma of the pulmonary artery. apropos of a case].	a case of leiomyosarcoma of the pulmonary artery in a 64-year old man without previous cardiovascular disease is reported. the clinical picture, which comprised episodes of paroxysmal dyspnoea associated with acute cor pulmonale, suggested pulmonary embolism. radioisotope perfusion study and pulmonary angiography seemed to confirm this diagnosis, but no improvement was obtained with a prolonged thrombolytic treatment. the presence of a median mass at ct led to exploratory thoracotomy and to the ...	1987	3122693
covalent coupling of 4-thiouridine in the initiator methionine trna to specific lysine residues in escherichia coli methionyl-trna synthetase.	a new method has been developed to couple a lysine-reactive cross-linker to the 4-thiouridine residue at position 8 in the primary structure of the escherichia coli initiator methionine trna (trnafmet). incubation of the affinity-labeling trnafmet derivative with e. coli methionyl-trna synthetase (metrs) yielded a covalent complex of the protein and nucleic acid and resulted in loss of amino acid acceptor activity of the enzyme. a stoichiometric relationship (1:1) was observed between the amount ...	1987	3122828
adenocarcinoma of the lung presenting as hematemesis secondary to jejunal metastasis: a case report and review of the literature.		2011	3126420
isolation of flagella from the archaebacterium methanococcus voltae by phase separation with triton x-114.	the flagella of methanococcus voltae were isolated by using three procedures. initially, cells were sheared to release the filaments, which were purified by differential centrifugation and banding in kbr gradients. flagella were also prepared by solubilization of cells with 1% (vol/vol) triton x-100 and purified as described above. both of these techniques resulted in variable recovery and poor yield of flagellar filaments. purification of intact flagella (filament, hook, and basal body) was ach ...	1988	3127380
enoxacin: in-vitro and animal evaluation as a parenteral and oral agent against hospital bacterial isolates.	enoxacin was evaluated in in-vitro tests and in studies of effectiveness and blood concentrations in the mouse. enoxacin was active against both susceptible and multiresistant hospital isolates of enterobacteriaceae, pseudomonas aeruginosa, haemophilus influenzae, neisseria gonorrhoeae and staphylococci. less susceptible were streptococci and anaerobes. of nine quinolones tested, only norfloxacin was equivalent in vitro. the mbcs of enoxacin were one- to twofold greater than the mics, and enoxac ...	1988	3129392
microprocessor-controlled mixing system for rebreathing equilibration.	a simple, economic, and accurate microprocessor system for the determination of mixed venous pco2 has been described. through the automatic gas mixing system, it is possible to facilitate the use of the rebreathing equilibration technique for the purpose of cardiac output calculations. it was also possible to flush the rebreathing bag within a brief time, providing the investigator with an automatic three-way valve driven by a solenoid.	2011	3131062
preliminary observations on alterations in prolactin, gonadotropins, e2-17b & progesterone in patients with breast cancer.		2011	3131240
immunocytochemical delineation of thyrotrophic area: origin of thyrotropin-releasing hormone in the median eminence.	to identify the specific thyrotropin-releasing hormone (trh)-containing neurons projecting to the median eminence (me), a retrograde tracing method with horseradish peroxidase (hrp) was combined with immunocytochemical staining for trh. three days after hrp injection restricted to the me, several trh-positive neuronal perikarya were found to contain hrp. such double-stained cells were exclusively distributed in the anterior parts of the periventricular nucleus and the most medial parts of the pa ...	1988	3135505
mechanism of inhibition of chromosomal beta-lactamases by third-generation cephalosporins.	the kinetic interactions of the beta-lactamase from enterobacter cloacae 908 r with ceftriaxone, cefotaxime, and ceftazidime have been examined in detail. with all of these cephalosporins, there is an initial rapid reaction involving opening of the beta-lactam that then decreases to a slower steady-state rate (kss) of beta-lactam hydrolysis (at 37 degrees c: ceftriaxone, kss = 0.044 s-1; cefotaxime, kss = 0.033 s-1; ceftazidime, kss = 0.011 s-1). more than stoichiometric quantities of beta-lacta ...	1988	3142012
[ethical aspects of therapeutic borderline situations in intensive care].		2011	3147854
effects of calcium-channel antagonists on tardive dyskinesia and psychosis.		2011	3153502
self-report vs. instrumental measure in the assessment of the subjective effects of d-amphetamine.		2011	3153509
prednisone-induced behavioral and biological changes in medically healthy volunteers.		2011	3153514
cleavage lines of the oral mucosa in japanese cadavers.	cleavage lines were experimentally reproduced in the oral mucosa of japanese cadavers. they were investigated macroscopically and histologically. the reproduced cleavage lines showed little directional variation by sex or age. from the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria.	2011	3165386
in-vitro and in-vivo activities of t-3262, a new pyridone carboxylic acid.	t-3262[p-toluenesulfonic acid salt of dl-7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acid monohydrate] is a new pyridone carboxylic acid with a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria. the activity of t-3262 against most enterobacteriaceae was comparable with that of ciprofloxacin except proteus spp. and providencia rettgeri and exceeded that of ofloxacin and norfloxacin. the activ ...	1988	3182417
serial myocardial lactate metabolic changes after intracoronary thrombolysis in evolving myocardial infarction.	to investigate whether early reperfusion (less than or equal to 3 hours) preserves aerobic myocardial metabolism in acute myocardial infarction, we examined serial changes in trans-cardiac lactate extraction after thrombolysis in 43 patients with acute antero-septal myocardial infarction. in the chronic phase, we also determined abnormally contracting segments as an index of infarct size and regional ejection fraction as an index of chronic regional cardiac function. in the early reperfusion gro ...	2011	3184437
experimental infection of sheep and goats with muellerius capillaris (protostrongylidae, nematoda).		1988	3188728
abdominal operations without nasogastric tube decompression of the gastrointestinal tract.	the routine use of nasogastric (ng) drainage during and after abdominal surgery was examined. one hundred and fifty patients who underwent various abdominal operations with a levine tube served as a control group (retrospective group). the tubeless study group (prospective group) of 150 patients was randomly and blindly divided into three equal subgroups. subgroup a patients were operated on without any ng tube. the tube in subgroup b patients was inserted after induction of anesthesia and remov ...	2011	3190004
isolation of p multocida f-3,4 from a calf in the uk.		1988	3195018
[evaluation on the capability of indole pyruvic acid production by members of proteeae on different brands of sulfide-indole-motility].	members of proteeae were vertically inoculated into different brands of sulfide-indole-motility (sim) medium for evaluating the capability of ipa production. a total of 328 clinical strains of tribe proteeae was used as tested organisms, including 186 proteus mirabilis strains, 62 morganella morganii strains, 31 proteus vulgaris strains, 27 providencia rettgeri strains, 14 providencia stuartii and 8 providencia alcalifaciens strains. seven different brands of sim medium used in this study are ky ...	1988	3197461
[antibacterial activities of monobactams against fresh clinical isolates].	antibacterial activities of monobactam antibiotics (carumonam (crmn) and aztreonam (azt] against gram-negative bacilli isolated from inpatients in the latter half of 1987 were investigated using penicillin (pc: piperacillin (pipc], cephems (ceps: ceftazidime (caz), cefotaxime (ctx), latamoxef (lmox), cefsulodin (cfs], carbapenem (imipenem (ipm] and pyridonecarboxylic acids (norfloxacin (nflx) and ofloxacin (oflx] as reference antibiotics. a total of 400 strains of 13 species, i.e. escherichia co ...	1988	3210297
hazardous effects of disinfection and sterilization chemicals.		2011	3215342
assessing familial aggregation of congenital cardiovascular malformations in case-control studies.	recent data indicate that the familial aggregation of congenital cardiovascular malformations (ccvm) varies with the type of defect in the index case. using a logistic regression model that allows for dependence among family members, we calculated the risk of any ccvm to case relatives compared with relatives of controls. data from 3,908 first-degree relatives of 570 matched cases and controls identified from 1981 through 1985 by the baltimore-washington infant study were used in the analyses. o ...	2011	3215508
studies on the host/parasite interface during the development of a pentastomid arthropod parasite in rodent intermediate hosts, with observations on protective surface membranes.	the changing structure of the cuticle of the arthropod pentastomid parasite porocephalus crotali, during growth to the infective stage in mouse and rattlesnake hosts, is described. the outermost cuticulin layer of the cuticle in instars ii-vi is elevated to form a dense mat of epicuticular hairs. since the vi larval cuticle is retained by the infective (vii) nymph as a protective sheath, effectively all stages in mice present a hairy surface to the host and this may constitute a physical barrier ...	1988	3232142
successive generations of child maltreatment. the children.	families were identified, in north-east wiltshire (uk), (population 200,000), in which there was a pattern of two or more generations of child maltreatment and where there were also two or more children maltreated in the current generation (born between 1960 and 1980). these children had high rates of mental handicap, backwardness, and antisocial behaviour, and there were also characteristic patterns of emotional disturbance. the post-neonatal death rate for the 294 index children was very high, ...	1999	3250697
[dental technical handling of palladium alloys].		1998	3250889
disease and pregnancy in adolescent girls.	the frequency of visits to the outpatient clinic, chief complaints, and pregnancies of adolescent girls were analyzed. the age distribution of adolescent girls who visited the clinic showed that the higher the age, the higher the frequency of menstrual cycle abnormalities. recently, increased sexual activity has been seen in teenagers and has caused problems, especially the increase in teenage pregnancies, contributing to increases in induced abortion. to avoid unwanted pregnancy of unmarried te ...	2011	3252729
[iatrogenesis of amalgam].		2012	3256040
the effects of clavulanic acid and sulbactam on beta-lactamase biosynthesis.	clavulanic acid and sulbactam were tested as inducers of beta-lactamase in 21 strains of gram-negative bacteria. beta-lactamase synthesis was inducible in all these strains, as demonstrated by the increased enzyme activities obtained when cells were grown in the presence of 10 mg/l of cefoxitin, the increase varying from 11- to 734-fold however, at the same concentration, neither inhibitor induced significant amounts of beta-lactamase, except in one strain of providencia rettgeri, where both wer ...	1988	3263350
in vitro and in vivo antibacterial activities of me1207, a new oral cephalosporin.	me1207 (pivaloyloxymethyl ester of me1206) is a new oral cephalosporin. me1206 is (6r,7r)-7-[(z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)- acetamido]-3-[(z)-2-(4-methylthiazol-5-yl)-ethyl]-cephem-4-carboxy lic acid. the susceptibilities of about 1,600 clinical isolates to me1206 were determined by the agar dilution method. me1206 showed a broad spectrum of activity against gram-positive and gram-negative bacteria. me1206 was more active than cefaclor, t-2525, and cefixime against staphylococcus ...	1988	3264132
regulation of ovarian cell growth through the local production of transforming growth factor-alpha by theca cells.	the rapid proliferation of a tissue often requires the local production of a specific growth factor. the ovarian follicle is a rapidly growing tissue which contains two primary somatic cell types, granulosa cells and theca cells. theca cells and granulosa cells were isolated from bovine ovaries and cultured to assess the possible local production of a growth factor within the ovarian follicle. serum-free conditioned medium from theca cells, but not from granulosa cells, was found to contain a co ...	1988	3264238
[urine bacterial flora and chemoantibiotic resistance: observations on ambulatory patients and hospitalized patients at the local health district no. 11 of fabriano (ancona)].	this paper reports the results of a study carried out on 4614 samples of urine from inpatients and outpatients according to the sex. the positive monomicrobic urine specimens were examined and isolated strains were tested against various antimicrobial drugs. our findings showed that 43.1% of urine specimens examined from inpatients and 38.4% from outpatients proved to be positive. among the bacterial species more frequently isolated, significant differences among enterobacter spp. in males and c ...	1988	3268917
contamination of freshly slaughtered pig carcasses with human pathogenic yersinia enterocolitica.	evidence is presented for the extent of contamination of freshly slaughtered pig carscasses with human pathogenic yersinia enterocolitica and shows the significance of faecal contamination as a source of infection. swab samples collected from the rectum and the surface of a total of 1458 pig carcasses were examined for the presence of human pathogenic y. enterocolitica. y. enterocolitica, biovar iv, serogroup 0:3, were isolated from the rectum of 360 pigs (24.7%). the organism was isolated from ...	1988	3275322
commercial identification systems often fail to identify providencia stuartii.	we tested 145 clinical isolates in an attempt to evaluate some of the most widely used commercial identification systems in europe in terms of their ability to identify providencia strains. two manual miniaturized systems (api 20e and enterotube ii) and three mechanized-automated systems (cobas-bact, sceptor system, and titertek-enterobac-rapid automated system) were evaluated. providencia alcalifaciens and providencia rettgeri strains were correctly identified by all systems in all cases, and i ...	1988	3277997
alteration of trichostrongylus colubriformis egg permeability by bacillus thuringiensis israelensis toxin.	a toxin from the bacterium bacillus thuringiensis israelensis is lethal to nematode eggs. exposure of eggs of the ruminant nematode trichostrongylus colubriformis to the toxin significantly increased the eggs' permeability to radiolabeled phenylalanine within 2 hr. calcium chloride inhibited the toxin-induced change in egg permeability. iodine staining of eggs that were exposed to the microbial toxin revealed that egg permeability was altered within 5 min and was dependent on the dose of toxin. ...	1987	3295166
in vitro activity and beta-lactamase stability of a new monobactam, b0-1165.	b0-1165 is a 1-carboxy-1-cyclopropoxyamino,4-fluoromethyl monobactam. it inhibited the majority of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, citrobacter diversus, aeromonas hydrophila, proteus mirabilis, proteus vulgaris, providencia rettgeri, providencia stuartii, yersinia enterocolitica, haemophilus influenzae, neisseria gonorrhoeae, and salmonella and shigella species at less than or equal to 0.125 microgram/ml. overall, its in vitro activity was similar to that of aztreona ...	1987	3300528
[pneumaturia and emphysematous cystitis. contribution of a new case with echographic images].		2012	3310528
in vitro and in vivo antibacterial activities of cs-807, a new oral cephalosporin.	cs-807 is a new oral prodrug of r-3746, a cephalosporin derivative, with potent in vitro and in vivo antibacterial activity against both gram-positive and gram-negative bacteria. the susceptibility of about 1,200 clinical isolates to r-3746 was determined by the agar dilution method. ninety percent or more of pathogens such as staphylococcus aureus, streptococci, escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, indole-positive and indole-negative proteus spp., providencia rettgeri, a ...	1987	3310868
allergy: a leading role in otitis media with effusion.	we have studied 35 children with seasonal allergic rhinitis confirmed by positive skin tests and rast to grass pollen. intranasal antigen provocation was performed to evaluate the function of the eustachian tube (et) and middle ear pressure (mep). tympanometry was used to evaluate the changes in mep, while valsava and toynbee tympanometric tests were employed to study the et function, and the changes in nasal airway resistance were measured by anterior rhinomanometry. et dysfunction (etd) and a ...	2012	3318349
arteriolar oxygen reactivity: where is the sensor?	the hypothesis that arterioles are intrinsically sensitive to oxygen was tested by comparing arteriolar diameter responses with local and global po2 changes in superfused hamster cheek pouch preparations. local po2 changes were produced by microapplication of fluid onto the surface of occluded or unoccluded aparenchymal arterioles or by cannulation and perfusion of arterioles in situ. global changes refer to po2 changes in the superfusate flowing over the entire preparation. local, effective po2 ...	2012	3318502
[intracellular mechanisms of cholestasis].		2005	3320466
[drug resistance of proteus vulgaris, proteus morganii and providencia rettgeri isolated from diagnostic specimens].		1987	3324173
microbiological perspectives of co-trimoxazole.	trimethoprim-sulfamethoxazole in vitro activity was compared with ampicillin, tetracycline, sulfonamide and trimethoprim against isolates of 24 gram-negative and 11 gram-positive species. the incidence of more than 10% of strains with minimal inhibitory concentrations above 32 mg/l was restricted to escherichia coli, shigella spp., klebsiella pneumoniae, providencia rettgeri, morganella morganii, methicillin-resistant staphylococcus aureus and staphylococcus epidermidis. occasionally, streptococ ...	1987	3325434
[the antimicrobial activity of sisomicin against fresh clinical isolates].	antimicrobial activities of sisomicin (siso) against clinical isolates obtained in the second half of 1986 were investigated together with other 4 aminoglycosides (ags) (gentamicin (gm), tobramycin (tob), dibekacin (dkb), amikacin (amk] and 2 cephems (cefotiam, cefotaxime), and were compared to the results reported in the period of late 1970's through early 1980's in japan. 1. the incidence of siso-resistant staphylococcus aureus in the present study was 18% and is comparable to that of the othe ...	1987	3327965
investigation of a providencia rettgeri strain that has enterobacterial common antigen in the immunogenic state.	antigenic material obtained by phenol-water extraction from providencia rettgeri strains, escherichia coli o:14 strains, and mutants of the e. coli o:14 strain were examined by the passive (indirect) hemagglutination technique, by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and by immune blotting (lipopolysaccharide (lps) blotting). providencia rettgeri 965, like e. coli o:14, was demonstrated to have an enterobacterial common antigen (eca) in the immunogenic form but, unlike e. c ...	1987	3328641
ganglion cells in the turtle retina contain the neuropeptide lant-6.	this study investigated the presence of the neurotensin-related hexapeptide, lant-6, in retinal ganglion cells and their central projections in the turtle pseudemys scripta elegans. immunocytochemical techniques demonstrated that many of the cells in the ganglion cell layer of the turtle retina could be labeled with an antiserum specific for lant-6. radioimmunoassay and chromatographic analysis confirmed the presence of lant-6-related peptides in retina, as well as brain. several molecular forms ...	2011	3339403