Publications
Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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first isolations of levinea-citrobacter cultures in czechoslovakia. | twenty-two strains corresponding by their biochemical properties to the genus levinea - citrobacter were isolated. six of the strains were referred to the species citrobacter diversus and 12 to c. freundii, whose properties are identical with those of l. malonatica and l. amalonatica, respectively. four strains differed from levinea organisms by some reactions, but were fully compatible with c. freundii (in the scheme of ewing and davis); two of them utilized malonate. the taxonomic position of ... | 1975 | 1170700 |
evaluation of tyrosine medium for the identification of enterobacteriaceae. | use of the tyrosine medium in the identification of members of the family enterobacteriaceae form the basis of this paper. six hundred and twenty-three strains were tested for their property of tyrosine degradation. three hundred and seventy-two strains were positive in 24 h and an additional eight strains were positive in 48 to 72 h. these positive strains consisted of all 344 strains of the proteus-providencia group, all 25 strains of citrobacter diversus, and three strains of atypical c. freu ... | 1975 | 1176617 |
four hour-test for the identification of enterobacteriaceae. | a set of 12 rapid biochemical tests--lysinedecarboxylase, ornithinedecarboxylase, beta-galactosidase, urease, hydrogensulphide, indole, acetoin, deoxyribonuclease, esculin, mannitol, raffinose and sorbitol--were selected from an original set of 13 tests and were found to give 98% accurate reactions within 4 hrs of incubation for the identification of bacteria belonging to enterobacteriaceae. this set permits identification on the genus and/or species level for escherichia, shigella, citrobacter, ... | 1975 | 1196260 |
citrobacter diversus at grace hospital, detroit, michigan. | over a six-month period from december 1973 to june 1974, isolations of citrobacter diversus were obtained from nine patients at grace hospital. our initial experience was with a patient who developed pneumonitis and a massive fatal empyema due to this organism. seven of the nine patients were 50 years of age. three patients had an underlying malignancy. four patients experienced significant clinical infections. isolations in three patients were considered to be commensal, and two isolations were ... | 1975 | 1211410 |
[nutrition and taxonomy of "enterobacteriaceae" and related bacteria. iii. nutritional characters and differentiation of the taxonomic groups (author's transl)]. | a batch of 186 strains belonging to the families enterobacteriaceae or vibrionaceae has been studied by determination, for each strain, of the "versatility" towards 146 organic substrates tested as sole source of carbon and energy. this study allowed to work out a classification of these strains into the 32 classes which have been previously described. in the present paper the nutritional characters of these classes are reported. on the basis of these characters, the 32 classes may be regrouped ... | 1975 | 1217784 |
[purulent meningitis in an infant, caused by citrobacter]. | 1975 | 1220165 | |
[local shwartzman phenomenon in germ-free guinea pig]. | eleven germfree and two monoassociated with the citrobacter guinea pigs, and 25 conventional animals were injected with the heat-inactivated citrobacter or e. coli for the induction of the local schwartzman phenomenon. all the gnotobiotic pigs gave a positive reaction. infiltration at the site of intracutaneous injection was found in all the conventionals, but in none of the gnotobiotics. the data are discussed from the aspect of primary and secondary sequelae of the absence of host microflora. | 1975 | 1227656 |
[a new group of the family enterobacteriaceae--the levinea group]. | 1975 | 1229208 | |
[sepsis due to citrobacter in the infant]. | 1975 | 1234355 | |
[frequency of detecting bacteria of the genera citrobacter and hafnia in different contingents of examined adults]. | a study of the incidence of bacteria of the citrobacter and hafnia genus in adults permitted to establish a greater occurrence of the mentioned microbes in the patients with various acute intestinal diseases in comparison with the healthy ones. bacteria of the citrobacter and hafnia genus were revealed in the patients with acute intestinal diseases of obscure etiology, which often were diagnosed as gastroenteritis, enteritis, etc. bacteria of the citrobacter and hafnia genus were revealed in the ... | 1975 | 1236718 |
formation of indoleacetic acid by intestinal anaerobes. | indoleacetic acid was produced from tryptophan by only three of 23 intestinal anaerobes studied. evidence is presented to show that the formation of indoleacetic acid proceeds through the intermediate, indolepyruvic acid, via transamination with alpha-ketoglutarate rather than by tryptamine pathway. | 1975 | 1236846 |
a specific cephalosporin-binding protein of citrobacter freundii. | 1. a cephalosporin-binding protein obtained from a strain of citrobacter freundii was purified to the extent of a single band in analytical and sodium dodecyl sulfate-containing disc electrophoresis. 2. the molecular weight determined by disc electrophoresis was 53 000. 3. the binding protein did not show any beta-lactamase activity at substrate concentrations examined: 6 mm to 100 mum of penicillins and 12 mm to 100 mum of cephalosporins. 4. in gel filtration, [14c]benzylpenicillin was found no ... | 1976 | 1247578 |
dna relatedness among species of enterobacter and serratia. | species of enterobacter and serratia were examined for deoxyribonucleic acid relatedness to klebsielleae, to atypical erwiniae, and to other members of enterobacteriaceae. deoxyribonucleic acid hybridization and then hydroxyapatite chromatography was the technique used to assess relatedness. strains of enterobacter cloacae formed two separate hybridization groups that correlate with the presence or absence of yellow pigment. pigmented e. cloacae were 75-100% related, but they were only 40-50% re ... | 1976 | 1260520 |
citrobacter diversus isolated from clinical material. | forty-seven strains of citrobacter diversus were isolated during a 12-month period from clinical material obtained from patients in a general hospital in israel. the majority of cultures (38) were recovered from urine and wound discharges. there was one case of septicemia. the biochemical reactions of all cultures were typical for this species, except one that was anaerogenic, and they could be divided into five biotypes (a through e). thirty-nine strains were identified serologically and found ... | 1976 | 1262451 |
the biosynthesis of ethyl lithocholate by fecal microorganisms. | 1976 | 1263499 | |
treatment of anaerobic pulmonary infections; carbenicillin compared to clindamycin and gentamicin. | twenty-three patients with anaerobic infections of the lung were treated with either two antibiotics, clindamycin and gentamicin (11 patients) or with a single antibiotic, carbenicillin (12 patients). cultures were obtained prior to therapy, either by transtracheal needle aspiration (17 patients) or thoracocentesis (six patients). anaerobic bacteria were found in all. fifteen patients had aerobic and facultative bacteria in addition. the anerobic isolates were peptostreptococci (12), peptococci ... | 1976 | 1277892 |
[the clinico-immunological characteristics and treatment of acute intestinal infections caused by enterobacteria of the genus citrobacter]. | 1992 | 1293835 | |
pilot studies on the occurrence of some infectious diseases in two different areas in south yemen (aden) (part ii. microbiology). | this paper is the second part of the article dealing with intestinal bacteria. the findings are relatively poor in comparing with the frequency of intestinal protozoa. among 83 stool specimens taken for bacteriological examination 14 isolations of different bacteria were proved. one s. muenchen was isolated from a 3 year old boy with fever, diarrhoea. five cases of alkalescens dispar 05 manit negative and 05 manit positive were identified. two of these cases were without clinical symptoms. all w ... | 1992 | 1300359 |
in vitro activity of sparfloxacin compared with those of five other quinolones. | the in vitro activity of sparfloxacin, a new difluorinated quinolone, was evaluated against 857 gram-positive and gram-negative clinical isolates and compared with those of ciprofloxacin, norfloxacin, ofloxacin, fleroxacin, and lomefloxacin. the mic of sparfloxacin for 90% of the members of the family enterobacteriaceae tested was 0.5 microgram/ml (range, 0.06 to 4.0 micrograms/ml); only for members of the genera serratia, citrobacter, and providencia were mics above 1 microgram/ml. some 90% of ... | 1992 | 1320362 |
role of is1 in the conversion of virulence (vi) antigen expression in enterobacteriaceae. | when escherichia coli hb101 harbors pwr127, a plasmid comprising the viab gene from citrobacter freundii wr7004 and the cole1-derived packc1, the strain produces the virulence (vi) antigen. vi antigen expression is abolished (vi- phenotype), however, when an is1 or is1-like dna element inserts into the viab region. to determine the sites of is1 insertion, pwr127 dnas extracted from 95 independently isolated vi- strains were analyzed by digestion with the restriction endonuclease psti and agarose ... | 1992 | 1324399 |
in vitro activity of opc-17116 compared to other broad-spectrum fluoroquinolones. | the in vitro activity of opc-17116 was compared to that of five similar fluoroquinolones (ciprofloxacin, enoxacin, norfloxacin, ofloxacin and temafloxacin). a total of 700 isolates from recent cases of clinical bacteremia were tested. fifty additional stock strains with well-characterized resistance mechanisms were also processed. the minimal concentrations inhibiting 90% of strains (mic90) of enterobacteriaceae species were for opc-17116 0.015-0.5 micrograms/ml and for ciprofloxacin 0.015-0.25 ... | 1992 | 1327789 |
epidemiological survey of genes encoding aminoglycoside phosphotransferases aph (3') i and aph (3') ii using dna probes. | the epidemiological survey of aph (3') i and aph (3') ii genes, at a time when the specific antibiotic pressure was very low, was carried out by dna-dna hybridization. the sample included 334 aminoglycoside resistant gram-negative bacteria collected from patients of a general hospital. of these, 251 hybridized with the aph (3') i-probe and 19 with the aph (3') ii-probe but only 190 strains showed high resistance levels (cim greater than 64 micrograms/ml) for kanamycin, neomycin and paromomycin. ... | 1992 | 1328557 |
characterization of the citrobacter freundii phoe gene and development of c. freundii-specific oligonucleotides. | the phoe gene of citrobacter freundii, encoding a pore-forming outer membrane protein, was cloned and its nucleotide sequence was determined. the homologies in terms of identical amino acids between the c. freundii phoe protein and those of escherichia coli, e. cloacae and klebsiella pneumoniae were 90%, 86% and 84%, respectively. two synthetic oligonucleotides, corresponding to hypervariable, cell surface-exposed regions of the protein, were tested for their specificity in polymerase chain reac ... | 1992 | 1337052 |
the comparative activity of fleroxacin, three other quinolones and eight unrelated antimicrobial agents. | the in vitro activity of fleroxacin, a new trifluorinated quinolone was evaluated against 432 bacterial isolates. fleroxacin was 1- to 2-fold less active than ciprofloxacin and at least as active as ofloxacin and lomefloxacin against most members of the family enterobacteriaceae. the mics of fleroxacin for 90% of strains tested (mic90) were < or = 0.25 micrograms/ml against all isolates of enterobacteriaceae except citrobacter freundii (mic90, 4 micrograms/ml) and serratia marcescens (mic90, 2 m ... | 1992 | 1337507 |
[plasmid localization and cloning of restriction modification genes from citrobacter freundii 4111 strain]. | over 60 producing strains of restriction endonucleases type ii have been found among 500 different strains, mostly enterobacteriaceae. the strain citrobacter freundii 4111 produces restriction endonuclease cfrbi, a new isoschisomer of styi. the genes of the restriction-modification system cfrbi were located on the multicopy plasmid pze8 containing the co1e1-type replicon and cloned to e. coli k802. the deletion variant of 3.2-kb pze8 which contains intact restriction-modification and a dna fragm ... | 1992 | 1338550 |
mobilization of nonconjugative pbr322-derivative plasmids from laboratory strains of escherichia coli to bacteria isolated from seawater. | mobilization of derivatives of plasmids pbr322 and pbr325 was shown to occur between escherichia coli k12 strains in lb-broth at 37 degrees c, provided a mobilizer plasmid (f') was present either together with the nonconjugative plasmid or in a second donor strain. evidence from restriction endonuclease analysis suggested that the mobilization was facilitated by a transposition phenomenon involving the "gamma-delta" sequence of f'. it was shown that mobilization of a derivative of pbr325 from e. ... | 1992 | 1341984 |
epidemiological role of arthropods detectable in health facilities. | a total of 161 arthropod specimens were collected from 55 sites in a health care facility during july and september 1990. of the 116 bacterial isolates obtained from their body surfaces 6% were from parasites (mosquitoes), 59% from eusynanthropic arthropods (tenebrionid beetles, flies, german cockroaches, wasps), 16% from hemisynanthropic arthropods (ants, spiders) and 19% from occasionally encountered insects (non-biting midges, moths, beetles). most (88%) of the isolated bacteria were gram-neg ... | 1992 | 1350604 |
interaction of citrobacter diversus strains with hep-2 epithelial and human umbilical vein endothelial cells. | more than 75% of neonates with citrobacter diversus meningitis develop brain abscesses. interaction of c. diversus strains with hep-2 and human umbilical vein endothelial cells (huvec) was studied to examine mechanisms related to brain abscess formation. two of 9 strains invaded hep-2 cells and 0 of 6 invaded huvec better than the others. c. diversus survived at least 20 h within hep-2 cells (in decreasing numbers). adhesion to hep-2 cells was increased in 3 of 4 strains expressing type 1 fimbri ... | 1992 | 1357038 |
[occurrence of p.fimbrii in strains from selected genera of enterobacteriaceae]. | this study was aimed at recognition of frequency of occurrence of p fimbriae in strains of escherichia coli isolated from samples of feces of children with symptoms of diarrhoea and at search of these adhesions in strains representing other than escherichia genera of enterobacteriaceae strains. one hundred forty laboratory strains were investigated. they belonged to genus citrobacter, enterobacter, hafnia, klebsiella, morganella, proteus, providencia, salmonella, shigella, and yersinia. also wer ... | 1992 | 1363960 |
dna sequence of a salmonella-specific dna fragment and the use of oligonucleotide probes for salmonella detection. | hybridization specificity of a 1.8-kb hindiii dna fragment isolated from salmonella typhimurium by a molecular cloning technique was confirmed by colony hybridization with 327 salmonella isolates of various serotypes and 56 non-salmonella isolates including enterobacteriaceae closely related to salmonella, such as escherichia coli, klebsiella, citrobacter and shigella. it was found that this 1.8-kb dna fragment was highly specific for all the salmonella isolates tested. the dna sequence of this ... | 1991 | 1367316 |
characterization of membrane-bound spermidine dehydrogenase of citrobacter freundii. | spermidine dehydrogenase found in the membrane fraction of citrobacter freundii ifo 12681 was solubilized with triton x-100 and further purified to homogeneity. the properties of the membrane enzyme were almost identical to those obtained from the soluble fraction of the organism with respect to molecular and catalytic properties. thus, binding properties of the enzyme to the bacterial membrane were checked. the ratio of enzyme activity found in the soluble fraction to the membrane fraction was ... | 1992 | 1369091 |
immunochemical characterization of citrobacter strain pcm 1487 o-specific polysaccharide- and core oligosaccharide-protein conjugates. | o-specific-polysaccharide and core oligosaccharide were isolated from citrobacter strain pcm 1487 lipopolysaccharide and purified. the polysaccharide was selectively devoid of 4-deoxy-d-arabinohexose residues. covalent conjugates of the modified o-specific polysaccharide and of the core oligosaccharide with tetanus toxoid were prepared. immunochemical characterization of these conjugates proved that they are strong immunogens. using monospecific rabbit antisera raised against the conjugates, the ... | 1992 | 1376131 |
citrobacter freundii septic arthritis. | septic arthritis in an 8 month old infant due to citrobacter freundii was treated successfully with a third generation cephalosporin. infections due to citrobacter are uncommon in this age group and are almost unknown as a cause of septic arthritis. | 1992 | 1389455 |
binding of mutagenic pyrolyzates to fractions of intestinal bacterial cells. | the binding of mutagenic pyrolyzates to cell fractions from some gram-negative intestinal bacteria and to thermally treated bacterial cells was investigated. 3-amino-1,4-dimethyl-5h-pyrido[4,3-b]indole (trp-p-1) and 3-amino-1-methyl-5h-pyrido[4,3-b]indole (trp-p-2) were effectively bound by several of the bacterial cells. the cell wall skeletons of all bacteria effectively bound trp-p-1 and trp-p-2. their cytoplasmic fractions retained trp-p-1 and trp-p-2, but to a lesser extent than the cell wa ... | 1992 | 1393830 |
[bacterial contamination of arthropods in a health facility]. | at 55 sites of a health institution in july and september 1990 a total of 161 specimens of arthropods were detected, 30 outdoors and 131 on the premises of the health institution. on their bodies 116 bacterial strains were isolated, mostly gram-negative rods (more than 85%), in particular spp. enterobacter, acinetobacter, klebsiella, citrobacter and pseudomonas. gram-positive cocci accounted for cca 12%, in particular strains of s. haemolyticus and s. hominis. the greatest number of strains was ... | 1992 | 1394473 |
antibacterial activity of the investigational oral and parenteral cephalosporin bk-218. | bk-218 is a novel cephalosporin with a dual route of administration and spectrum of activity most similar to that of second-generation cephalosporins. bk-218 was active against streptococcus pneumoniae, haemophilus influenzae and moraxella catarrhalis but strains resistant to penicillins had higher mics. bk-218 had greater activity (8-fold) than cefuroxime or cefaclor against oxacillin-susceptible staphylococcus spp. moderate bk-218 activity was observed against neisseria gonorrhoeae and commonl ... | 1992 | 1396735 |
comparative in vitro activity and beta-lactamase stability of ru29246, the active metabolite of hr916b. | hr 916b is a new orally absorbed cephalosporin. in tests its active metabolite, ru29246, inhibited streptococcus pyogenes, streptococcus agalactiae and streptococcus pneumoniae at less than or equal to 0.12 micrograms/ml, which is similar to the antibacterial activity of cefuroxime, and was more active than cefaclor. it was also more active (mic 2 micrograms/ml) than cefixime, cefuroxime, cefaclor and cefotaxime against staphylococci. ru29246 inhibited escherichia coli, klebsiella pneumoniae, ci ... | 1992 | 1396779 |
citrobacter sepsis in infants. | a study of blood cultures from 320 cases of neonatal sepsis showed 136 (42.5%) to be positive for bacterial growth; of these 82 (60.29%) isolates being gram negative bacilli. citrobacter was the commonest gram negative bacilli isolated. other commonly isolated gram negative organisms were pseudomonas, klebsiella, salmonella typhimurium, acinetobacter and escherichia coli. antibiotics susceptibility pattern revealed the isolates to be resistant to commonly used antibiotics. | 1992 | 1398863 |
cefclidin (e1040), a novel cephalosporin: lack of selection of beta-lactamase overproducing mutants in an in vitro pharmacokinetic model system. | the bactericidal activity of cefclidin (e1040), a new cephalosporin, against a clinical strain of citrobacter freundii was compared with that of ceftazidime in a two-compartment in vitro pharmacokinetic model system designed to simulate plasma concentrations in humans for 12 hours after intravenous administration of a 1 g dose. both cefclidin and ceftazidime showed rapid bactericidal activity against c. freundii. however, during the simulation of ceftazidime treatment, regrowth was observed afte ... | 1992 | 1399855 |
specific detection of campylobacter jejuni and campylobacter coli by using polymerase chain reaction. | development of a routine detection assay for campylobacter jejuni and campylobacter coli in clinical specimens was undertaken by using the polymerase chain reaction (pcr). an oligonucleotide primer pair from a conserved 5' region of the flaa gene of c. coli vc167 was used to amplify a 450-bp region by pcr. the primer pair specifically detected 4 strains of c. coli and 47 strains of c. jejuni; but it did not detect strains of campylobacter fetus, campylobacter lari, campylobacter upsaliensis, cam ... | 1992 | 1400961 |
novobiocin, brilliant green, glycerol, lactose agar: a new medium for the isolation of salmonella strains. | we describe a medium, novobiocin, brilliant green, glycerol, lactose (nbgl) agar, for the routine isolation of salmonella strains from stool samples. the nbgl agar principle involved the use of the antisaprophytic effect of brilliant green and novobiocin. glycerol and lactose were added in order to distinguish between citrobacter and salmonella. nbgl was used in parallel with salmonella-shigella (ss) and hektoen (h) agar for culturing 2,853 stool samples, of which 184 were confirmed to be salmon ... | 1992 | 1410796 |
in vitro activity and susceptibility to hydrolysis of s-1006. | the in vitro activity of s-1006, the active component of a new orally absorbed cephalosporin, s-1108, inhibited 90% of staphylococcus aureus isolates at less than or equal to 2 micrograms/ml, 90% of group a, b, c, f, and g streptococci and streptococcus pneumoniae isolates at less than or equal to 0.12 microgram/ml, and all haemophilus influenzae isolates at less than or equal to 0.06 microgram/ml. although 50% of the members of the family enterobacteriaceae were inhibited by less than or equal ... | 1992 | 1416835 |
in vitro activity of mc-352, a new 16-membered macrolide. | the in vitro activity of mc-352, 3,4'-dideoxy-5-o-mycaminosyltylonolide, was compared with those of erythromycin, clarithromycin, and rokitamycin. the mc-352 mic90 (mic for 90% of isolates) for erythromycin-susceptible staphylococcus aureus and staphylococcus epidermidis was less than or equal to 1 microgram/ml, similar to those of the other agents. the mc-352 mic50 for erythromycin-resistant s. aureus was 2 micrograms/ml, similar to that of rokitamycin. the mc-352 mic90 (0.12 micrograms/ml) for ... | 1992 | 1416853 |
antibacterial activity of ru44790, a new n-tetrazolyl monocyclic beta-lactam. | ru44790 belongs to a new class of synthetic monocyclic beta-lactam antibiotics which feature a bioisosteric tetrazole moiety instead of the more classical acidic functions at the n-1 position of the beta-lactam ring. its antibacterial activity was evaluated against some 900 strains and was compared with those of other recent beta-lactam derivatives, especially aztreonam. ru44790 is endowed with potent activity against gram-negative bacteria. at less than or equal to 0.6 micrograms/ml, ru44790 in ... | 1992 | 1416860 |
cloning and expression of the erwinia herbicola tyrosine phenol-lyase gene in escherichia coli. | the tyrosine phenol-lyase (tpl) gene of erwinia herbicola was cloned and expressed in escherichia coli, and the complete nucleotide sequence of the gene determined. the tpl gene comprises 1368 bp, encoding 456 amino acids which have 90% amino acid identity with tpl from citrobacter freundii. after replacing the 5'-flanking region of the tpl gene with the e. coli lac promoter, tpl protein could be hyperproduced constitutively in e. coli without induction by l-tyrosine. | 1992 | 1418690 |
[antimicrobial activities of major oral antibacterial agents against clinically isolated microbial strains from inpatients]. | antimicrobial activities were examined for major antibacterial agents against clinically isolated microbial strains which were isolated and identified from materials collected from inpatients with various infections in 1988, 1989 and 1990, and the following conclusions were obtained. 1. among strains isolated each year, methicillin-resistant staphylococcus aureus (mrsa) were found frequently. 2. ceps-resistant escherichia coli strains were observed among strains isolated each year. 3. increasing ... | 1992 | 1433903 |
[antibacterial activities of sisomicin against fresh clinical isolates]. | to investigate antibacterial activities of sisomicin (siso), mics of siso as well as other aminoglycosides (ags) were determined against many clinical isolates which were obtained in 1991. results are summarized below: 1. no siso-resistant strains were observed among isolates of escherichia coli, citrobacter diversus, klebsiella pneumoniae, klebsiella oxytoca, enterobacter aerogenes, proteus mirabilis and morganella morganii. 2. in comparison with the results of our previous study against isolat ... | 1992 | 1433905 |
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1988). i. susceptibility distribution]. | isolation frequencies and sensitivities to antibacterial and antibiotic agents were investigated on 801 bacterial strains isolated from patients with urinary tract infections in 9 hospitals during the period of june to november 1988. of the above total bacterial population, gram-positive bacteria accounted for 29.3% and a majority of them were enterococcus spp. gram-negative bacteria accounted for 70.7% and most of them were escherichia coli. 1. enterococcus faecalis: vancomycin was most active ... | 1992 | 1433906 |
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1988). iii. secular changes in susceptibility]. | sensitivities to various antibacterial and antibiotic agents of strains of escherichia coli, klebsiella spp., proteus spp., citrobacter spp., enterobacter spp., serratia marcescens and pseudomonas aeruginosa isolated from patients with urinary tract infections (utis) in 9 hospitals during june to november 1988 were compared with those in the same period of previous year according to a classification, uncomplicated utis, complicated utis without indwelling catheter, and complicated utis with indw ... | 1992 | 1433908 |
analysis of polar lipids from some representative enterobacteria, plesiomonas and acinetobacter by fast atom bombardment-mass spectrometry. | fast atom bombardment-mass spectrometry (fab-ms) was used to analyse lipid extracts of bacteria to assess its usefulness for analysing anionic phospholipids of potential chemotaxonomic value. the following micro-organisms were tested: acinetobacter calcoaceticus, acinetobacter sp., citrobacter freundii, enterobacter cloacae (2 strains), escherichia coli (3 strains), hafnia alvei, klebsiella oxytoca, klebsiella pneumoniae, morganella morganii, plesiomonas shigelloides, proteus mirabilis (3 strain ... | 1992 | 1447059 |
evaluation of the autoscan-w/a rapid system for identification and susceptibility testing of gram-negative fermentative bacilli. | the autoscan-walk-away (w/a) system for identification and susceptibility testing was evaluated for 400 gram-negative fermentative bacteria by using the api 20e (366 isolates) and/or tube biochemical tests as the reference identification system and a frozen microdilution mic tray system for susceptibility testing. the w/a system performed well for identification of this group of organisms representing 14 genera and 30 species, showing a sensitivity of 96% and results available in 2 h. of the 16 ... | 1992 | 1452661 |
analysis of relationships among isolates of citrobacter diversus by using dna fingerprints generated by repetitive sequence-based primers in the polymerase chain reaction. | oligonucleotide probes which match consensus sequences of the repetitive extragenic palindromic (rep) element hybridize to genomic dna of diverse bacterial species. primers based on the rep sequence generate complex band patterns with genomic dna in the polymerase chain reaction (pcr), a technique named rep-pcr. we used rep-pcr with genomic dna to fingerprint 47 isolates of citrobacter diversus. previously, 37 were assigned electrophoretic types (ets) by multilocus enzyme electrophoresis and 35 ... | 1992 | 1452663 |
[an increase in the immunogenicity of bacterial antigens under the influence of one of the derivatives of muramyl dipeptide]. | as revealed in animal experiments, glucosaminylmuramyl dipeptide (gmdp), the synthetic analog of muramyl dipeptide, when introduced intraperitoneally in a single injection or orally, exhibits adjuvant activity with respect to citrobacter 0-antigens, shigella flexneri and enhances the protective properties of dysentery and pertussis vaccines. the stimulating properties of gmdp depend on its dose, the route of its administration, the time elapsed after its administration, its ratio to the concomit ... | 1992 | 1455969 |
evaluation of progesterone treatment to create a model for equine endometritis. | to investigate a model for equine endometritis, 12 mares with normal reproductive tracts were divided into 2 groups. all mares received progesterone in oil, 250 mg im, daily. at 5 days after initiation of progesterone administration, the uteri were inoculated with 10(6) colony forming units of pseudomonas aeruginosa. the day of inoculation was designated day 0. on day 6, endometrial swab samples yielded p. aeruginosa in 5 mares; samples from the other 7 mares yielded heavy growth of escherichia ... | 1992 | 1459059 |
antifungal anthracycline antibiotics, spartanamicins a and b from micromonospora spp. | spartanamicins a and b, two antifungal antibiotics, were produced by a culture of micromonospora spp. strain no. msu-43097 (atcc 53803), isolated from a potted soil containing asparagus (asparagus officinalis l.) plants. the antibiotics were isolated from the mycelial cake using organic solvents. the structures of spartanamicins a and b were determined by spectral and chemical means. spartanamicin b is more active as an antifungal compound than it's analogue, a. the minimum inhibitory concentrat ... | 1992 | 1468980 |
[can the reactions of lysine oxidative deamination be used for the biochemical differentiation between salmonella sp. and citrobacter freundii?]. | 1992 | 1472785 | |
beta-lactamase stability and inhibitory activity of meropenem combined with a potent antibacterial activity. | the affinity of meropenem for various known types of beta-lactamases and its stability to them were tested in comparison with other beta-lactams, including imipenem. meropenem exhibited a marked stability to all beta-lactamases tested and was only hydrolyzed by xanthomonas maltophilia beta-lactamase, as were other beta-lactams. this was responsible for the potent antibacterial activities of meropenem against beta-lactamase-producing strains. meropenem and imipenem had almost the same, relatively ... | 1992 | 1473360 |
growth temperature-dependent activity of glycerol dehydratase in escherichia coli expressing the citrobacter freundii dha regulon. | using the cosmid pwe15, a genomic library of citrobacter freundii dna in escherichia coli ecl707 was prepared and screened for glycerol utilization. six out of approximately 3000 clones were positive. one clone, harboring the recombinant cosmid prd1, expressed glycerol dehydratase in high activity when grown at 28 degrees c but not at 37 degrees c. the growth temperature had little effect on the activity of the other enzymes encoded by the dha regulon. when the glycerol-containing medium was sup ... | 1992 | 1478463 |
[effect of meropenem on fecal flora in children]. | meropenem (mepm, sm-7338), a novel parenteral carbapenem antibiotic, was examined for its effect on intestinal flora in children. seven children with infectious diseases (3 male and 4 female children of age's ranging from 4 months to 8 years and 9 months weighing from 7.3 to 23.0 kg) were treated with mepm at doses ranging 10.3 to 40.5 mg/kg 3 or 4 times a day for 6 to 12 days. before, during and after the treatment, identities and numbers of various bacteria contained in 1 g of feces were deter ... | 1992 | 1479688 |
survey of the prevalence of beta-lactamases amongst 1000 gram-negative bacilli isolated consecutively at the royal london hospital. | beta-lactamase expression was examined in 1000 consecutive gram-negative bacilli isolated from urine, wound swab, sputum or blood specimens received at the microbiology laboratory of the royal london hospital. this survey, performed between january and april, 1991, followed a similar study undertaken in early 1982. the distribution of species was similar in the two surveys, except that the proportion of pseudomonas aeruginosa isolates had increased from 11% in 1982 to 17.5% in the present study. ... | 1992 | 1490917 |
[synergistic action of cefodizime with other antimicrobial agents on clinically isolated microorganisms. ii. synergistic action with sisomicin]. | cefodizime (cdzm) possesses a broad antimicrobial spectrum and a relatively long half life in the blood. in addition, it shows excellent therapeutic efficacies in the treatment of infections in leukopenic animal models, hence it is expected that cdzm may have good efficacies against various infections in immunocompromised hosts. in the meantime, sisomicin (siso) not only has strong antibacterial activities against gram-negative rods (gnr), but has relatively low nephrotoxicity and ototoxicity. t ... | 1992 | 1495193 |
[detection of extended-spectrum beta-lactamases by the rapid atb e technique. value of the api v2.1.1 expert system]. | twenty-two extended-spectrum betalactamase-producing strains of enterobacteriaceae recovered in the authors' hospital were tested using the rapid atb e coupled with the api v2.1.1. expert system. the expert system detected 90.9% of esbl-producing strains. two strains producing a shv2 and a ctx1, respectively, escaped detection by the expert system despite concomitant resistance to aminoglycosides. | 1992 | 1495843 |
[spondylitis due to citrobacter diversus. case report and review of citrobacter diversus infections]. | citrobacter diversus (c.d.) is an unusual human pathogen. its pathogenic potency is small or nil, and in most cases it is isolated in combination with other organisms. most isolates are of indeterminate clinical significance. occasionally c.d. may cause opportunistic infections, especially in subjects with primary or secondary conditions of poor host defense, immunosuppressed patients or neonates. we report a case of c.d. vertebral osteomyelitis following c.d. pneumonia. the osteomyelitis was cu ... | 1992 | 1496345 |
uranium bioaccumulation by a citrobacter sp. as a result of enzymically mediated growth of polycrystalline huo2po4. | a citrobacter sp. accumulates heavy deposits of metal phosphate, derived from an enzymically liberated phosphate ligand. the cells are not subject to saturation constraints and can accumulate several times their own weight of precipitated metal. this high capacity is attributable to biomineralization; uranyl phosphate accumulates as polycrystalline huo2po4 at the cell surface. the precipitated metal is indistinguishable from crystalline huo2po4.4h2o grown by chemical methods. | 1992 | 1496397 |
the effect of amino acid substitution at position 219 of citrobacter freundii cephalosporinase on extension of its substrate spectrum. | the cephalosporinase of citrobacter freundii gn346 is a class-c beta-lactamase comprising 361 amino acids. the substitution of the glutamic acid at position 219 in the enzyme by lysine was previously shown to broaden its substrate specificity to unfavorable substrates such as oxyimino cephalosporins [tsukamoto, k., ohno, r. & sawai, t. (1990) j. bacteriol. 172, 4348-4351]. to investigate the cause of this phenomenon, glu219 was changed to glutamine, cysteine or tryptophan. all the resultant enzy ... | 1992 | 1499556 |
in vitro and in vivo antibacterial activities of levofloxacin (l-ofloxacin), an optically active ofloxacin. | the antibacterial activity of levofloxacin was compared with those of ofloxacin, ciprofloxacin, and other antibiotics. in general, levofloxacin was equally active or up to fourfold more active than ofloxacin against all 801 organisms tested. levofloxacin was twofold [corrected] more active than ciprofloxacin against streptococcus pneumoniae and 2- to 4-fold more active than ciprofloxacin against staphylococcus aureus, xanthomonas maltophilia, and bacteroides fragilis. levofloxacin was two- to ei ... | 1992 | 1503449 |
gangrenous stomatitis following measles. | 1992 | 1506107 | |
[clinical pharmacology and efficacy of meropenem]. | we studied a newly developed carbapenem, meropenem (mepm), and obtained the following results. 1. pharmacokinetics of mepm in pediatrics was examined in 3 patients. mepm was injected intravenously at a dose of 16-22 mg/kg by drip infusion for 30 minutes, and its concentrations in serum and urine were determined using bioassay. the average peak value of serum levels of mepm was 38.4 micrograms/ml and t1/2 beta of mepm was 1.26 hours. the urinary recovery rate for the first 6 hours after administr ... | 1992 | 1507403 |
septicemia in granulocytopenic patients: a shift in bacterial etiology. | 35 episodes of septicemia in 33 patients occurred among 269 consecutive patients with granulocytopenia (granulocyte cell count less than or equal to 0.5 x 10(9)/l) during the 7-year period 1982-1988. 59% of isolated bacteria were gram-positive (staphylococcus aureus, staph. epidermidis, streptococcus species and pneumococcus) and 41% gram-negative (pseudomonas aeruginosa, escherichia coli, klebsiella pneumoniae, enterobacter, acinetobacter and citrobacter). compared to the 7-year period 1975-198 ... | 1992 | 1509241 |
nucleotide sequence of the ampc-ampr region from the chromosome of yersinia enterocolitica. | the nucleotide sequence of a 3.1-kb region from the chromosome of the yersinia enterocolitica o:5b strain ip97 containing the gene for an inducible chromosomal cephalosporinase has been determined. the cephalosporinase gene was homologous to other enterobacterial chromosomal cephalosporinase genes, and it was accompanied by a gene homologous to the regulatory ampr gene. the arrangement of genes in the y. enterocolitica ampcr unit was identical to that in the enterobacter cloacae and citrobacter ... | 1992 | 1510392 |
in vitro and in vivo activities of sce-2787, a new parenteral cephalosporin with a broad antibacterial spectrum. | sce-2787, a new cephalosporin having a condensed azolium moiety in the 3 position and an aminothiadiazolyl group in the 7 beta side chain, was evaluated for its in vitro and in vivo activities in comparison with those of ceftazidime, flomoxef, cefpirome, and e1040. against methicillin-susceptible strains of staphylococcus aureus and staphylococcus epidermidis, sce-2787 was more active than ceftazidime and e1040 and was as active as flomoxef and cefpirome, with mics for 90% of strains tested (mic ... | 1992 | 1510428 |
in vitro activity and beta-lactamase stability of ljc 10,627. | the in vitro activity of ljc 10,627, a new carbapenem, was compared with those of imipenem, cefotaxime, ceftazidime, and gentamicin. ljc 10,627 inhibited 90% of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, enterobacter aerogenes, enterobacter agglomerans, enterobacter cloacae, hafnia alvei, citrobacter freundii, citrobacter diversus, proteus mirabilis, morganella morganii, proteus rettgeri, serratia marcescens, pseudomonas cepacia, salmonellae, shigellae, aeromonas, and yersiniae ... | 1992 | 1510436 |
anaerobic malonate decarboxylation by citrobacter diversus. growth and metabolic studies, and evidence of atp formation. | citrobacter diversus atcc 27156 was able to grow by decarboxylation of malonate to acetate under strictly anaerobic conditions, in the presence of yeast extract. the growth yield, corrected for growth on yeast extract, was 2.03 g cell dry mass per mol malonate. the addition of malonate to atp-depleted cell suspensions (less than 0.2 nmol atp/mg cell protein) resulted in a rapid increase in cellular atp levels to between 4.5 and 6.0 nmol/mg cell protein. intact cells decarboxylated malonate at ra ... | 1992 | 1510573 |
brominated phospholipids as a tool for monitoring the membrane insertion of colicin a. | the intrinsic fluorescence of the colicin a thermolytic fragment does not change after insertion into normal phospholipid vesicles and is thus an unsuitable probe for monitoring the membrane insertion process. in this paper, we report the results of studies on the quenching of this fluorescence by brominated dioleoylphosphatidylglycerol (br-dopg) vesicles. bromine atoms located at the midpoint of the phospholipid acyl chain quench the tryptophan fluorescence, indicating contact between fluoropho ... | 1992 | 1510921 |
[clinical laboratory approach to evaluate efficacy of amikacin. reevaluation of in vitro mic break points in disc susceptibility test]. | antimicrobial activities of amikacin (amk) against 269 strains of various clinical isolates obtained in 1989 were determined and the reliability of the amk disc susceptibility test in estimating approximate values of mics was studied. in addition, clinical significance of various systems for the interpretation of the disc tests was evaluated to determine more useful method in the evaluation of clinical efficacy of amk. included in the study were a 3 category system of nccls, a 4 category system ... | 1992 | 1512934 |
the threat of resistance to the new oral cephalosporins. | phenotypic resistance to beta-lactam antibiotics is mainly due to the prevalence of beta-lactamases. the most common enzymes responsible for resistance to aminopenicillins and older (1st generation) cephalosporins are the tem-1, tem-2, oxa-1 and shv-1 enzymes, all of which are plasmid-mediated. the recent development of oral cephalosporins sharing structural features and an antimicrobial spectrum comparable to that of 3rd-generation cephalosporins has provided highly active compounds for the man ... | 1992 | 1516458 |
evaluation of coliforms as indicators of water quality in india. | the total and thermotolerant coliform counts in rural drinking water derived from ground water, piped supplies and surface water are reported for a number of areas in india. to evaluate these counts as indicators of recent faecal contamination the total coliforms and thermotolerant coliforms isolated have been identified. thermotolerant escherichia coli formed 11.7% of the total coliforms and 75.1% of the thermotolerant coliforms. citrobacter sp. (20.4%) and klebsiella sp. (50.9%) were the other ... | 1992 | 1517177 |
evaluation of aztreonam in the treatment of serious gram-negative infections in a university hospital in saudi arabia. | the efficacy and safety of aztreonam were evaluated in an open trial at king khalid university hospital, riyadh, saudi arabia. a total of 45 critically-ill adult patients were enrolled in the study. all patients with documented gram-negative infection were treated with aztreonam as monotherapy. antibiotics active against only gram-positive and/or anaerobic organisms were allowed. twenty cases were clinically evaluable. eleven had lower respiratory tract infections (pneumonia), 3 had urinary trac ... | 1992 | 1517810 |
expression of vi antigen in escherichia coli k-12: characterization of viab from citrobacter freundii and identity of viaa with rcsb. | the vi antigen in salmonella typhi is stably expressed and may act to protect the strain against the defensive system of the host. citrobacter freundii, not usually a common human pathogen, also expresses the vi antigen but expresses it unstably, exhibiting a reversible transition between the vi+ and vi- states. two widely separated chromosomal regions, viaa and viab, are needed for vi synthesis. escherichia coli k-12 harboring a functional viab plasmid can also express vi antigen, but the clone ... | 1992 | 1522067 |
[antimicrobial activities of ceftriaxone against clinically isolated strains]. | antibiotic activities (mics) of ceftriaxone (ctrx) against 1,210 strains of bacteria including 28 spp. isolated in 1987 and 1990 were compared with those of other cephems. 1. when compared to data on clinically isolated strains reported in the early 1980s, strains of the following species isolated in 1990 showed extremely elevated mic90s of ctrx: staphylococcus spp., streptococcus pneumoniae, escherichia coli, citrobacter spp., enterobacter spp., serratia spp., proteus vulgaris, morganella morga ... | 1992 | 1522669 |
immunochemical studies on sialic acid-containing lipopolysaccharides from enterobacterial species. | lipopolysaccharides with sialic acid as a component were isolated from six bacterial serovars of the family enterobacteriaceae. sds-polyacrylamide gel electrophoresis, immunoblotting and passive haemagglutination demonstrated that epitopes are localized in the o-specific polysaccharide of lipopolysaccharides. the strains were tested for a serological relationship; the only distinct cross-reactivity recorded was between escherichia coli serovars o24 and o56. the molecular mimicry phenomenon was f ... | 1992 | 1524838 |
in vitro activity of cefodizime. | cefodizime is a bactericidal cephem with the typical broad spectrum activity of an aminothiazolyl cephalosporin, including both gram-positive and gram-negative bacteria: its mic90 is 0.125 mg/l for streptococcus pneumoniae, streptococcus pyogenes and other streptococci; and 0.05 mg/l for haemophilus spp., neisseria meningitidis, neisseria gonorrhoeae and moraxella catarrhalis; while beta-lactamase positive strains of m. catarrhalis require 1 mg/l. less than 1 mg/l is needed for escherichia coli, ... | 1992 | 1526673 |
neonatal septicaemia in an african city of high altitude. | ninety-nine cases of neonatal septicaemia prospectively seen over a 3-year period in a large cosmopolitan african city of high altitude is presented. an incidence of 6.5 per 1000 live births was noted. though the most important pathogens were klebsiella spp. and staphylococcus aureus, citrobacter difficile and alkalegenes faecalis were the pathogens associated with a high mortality rate. low birth weight infants were significantly more affected. the overall mortality rate was 27.3 per cent. the ... | 1992 | 1527816 |
bacteriophage lytic patterns for identification of salmonellae, shigellae, escherichia coli, citrobacter freundii, and enterobacter cloacae. | a series of bacteriophages specific for escherichia coli (e-1, e-2, e-3, and e-4), citrobacter freundii (phi i, phi ii, and phi iii), enterobacter cloacae (ent), and shigella spp. (sh) have been isolated from hospital sewage. these bacteriophages, in combination with felix salmonella phage o-i, were used as a diagnostic phage typing set which included seven phage preparations: o-i, c (phi i and phi iii), sh, e (e-1 and e-2), ce (phi ii and e-3), e-4, and ent. after 20,280 cultures of 27 species ... | 1992 | 1551974 |
citrobacter diversus brain abscess: case reports and molecular epidemiology. | citrobacter diversus brain abscess occurred in two infants in aberdeen, 5 months apart. these are the first reported cases of this condition in the uk since 1976. restriction endonuclease analysis with saci enzyme showed blood and csf isolates from both patients to be identical and different from 10 other clinical isolates of c. diversus and one c. amalonaticus strain. furthermore, isolates of c. diversus from patients belonged to biotype "d" whereas control isolates were of biotypes "a" or "e". ... | 1992 | 1560449 |
the vi antigen of salmonella typhi: molecular analysis of the viab locus. | strains of salmonella typhi isolated from the blood of patients with typhoid fever invariably express a capsular polysaccharide, termed the vi antigen. vi antigen expression is controlled by two separate chromosomal loci, viaa and viab. the viaa locus is commonly found in enteric bacteria. in contrast, the viab locus appears to be specific to vi-expressing strains of salmonella and citrobacter. here the cloning, expression and analysis of viab determinants from s. typhi ty2 is described. whole-c ... | 1992 | 1564441 |
[typing by isoelectric focusing of beta-lactamase enzymes in klebsiella and enterobacter strains resistant to the new beta-lactam antibiotics]. | resistance to new generation beta-lactam antibiotics in gram-negative bacteria is increasing worldwide. this resistance is due to ebs enzymes in klebsiella spp., and type-i chromosomal enzymes in enterobacter spp., citrobacter, p. aeruginosa, providencia, m. morganii and s. marcescens. in this study, the types of beta-lactamases in 16 klebsiella spp. and 15 enterobacter spp. which are resistant to newer beta-lactam antibiotics was investigated by isoelectric focusing. the results of the study sh ... | 1992 | 1574017 |
further observations on the serological response to experimental salmonella typhimurium in chickens measured by elisa. | an indirect elisa developed for the serological detection of salmonella typhimurium in chickens using lipopolysaccharide as detecting antigen has been evaluated further in experimental infections. following oral infection of 24-week-old laying hens with an invasive strain of s. typhimurium, high titres of specific circulating igg were induced which were maintained for 20 weeks. similar igg titres were found in egg yolk. when 4-day-old chickens were infected high antibody titres persisted for 45 ... | 1992 | 1582466 |
[a study carried out in 1989 at the sant'antonio hospital of ovada on food poisoning in personnel handling and selling food products and drinks]. | the search for salmonella spp in the faeces and of staphylococcus aureus in pharyngeal pads during examinations for the renewal of the medical fitness booklet, leads to a number of considerations of a technical-health and economic nature. whereas the identification of staphylococcus aureus is fairly straightforward, that of salmonella in the faeces is not so easy. doubtful results are commonplace and bacteria are often found with features similar to salmonella; this means extra examinations with ... | 1992 | 1589136 |
[monthly variation of viable count and coliforms count of sandpits in parks]. | field and experimental microbiological investigations of samples from sandpits from 5 parks were performed 2 times a month for 1 year, january-december 1990. total viable count from the sandpits was highest in the surface layer sample than the inner layer throughout the year. however, there was no such tendency in the number of coliforms and enterobacter, escherichia coli, citrobacter. the number of bacteria on the surface and inner layer was high from april to june, and in september and october ... | 1992 | 1600209 |
the polypeptide chain fold in tyrosine phenol-lyase, a pyridoxal-5'-phosphate-dependent enzyme. | the tyrosine phenol lyase (ec 4.1.99.2) from citrobacter intermedius has been crystallised in the apo form by vapour diffusion. the space group is p2(1)2(1)2. the unit cell has dimensions a = 76.0 a, b = 138.3 a, c = 93.5 a and it contains two subunits of the tetrameric molecule in the asymmetric unit. diffraction data for the native enzyme and two heavy atom derivatives have been collected with synchrotron radiation and an image plate scanner. the structure has been solved at 2.7 a resolution b ... | 1992 | 1601133 |
bacteriological quality of infant feeding bottle-contents and teats in addis abeba, ethiopia. | bacteriological quality of 244 infant feeding-bottles and 61 teats were studied from january 1989 to november 1989. samples were collected from feeding-bottles of babies who were brought by nursing mothers to clinics and hospitals for varying complaints. of the 244 bottle-content samples, 144 (59%) harboured more than 2 x 10(6) colonies of bacteria per ml. of samples. the predominant bacterial isolates both from bottle-contents and teat-swabs were the coliform group of bacteria, such as e. coli, ... | 1992 | 1606947 |
[the pathogen spectrum and its resistance behavior in children with urinary tract infections in angola]. | in 225 children (135 boys, 90 girls) suffering from clinical relevant urinary tract infection the bacterial spectrum and resistance behaviour to routinely used antibiotics were evaluated. in 65.4% of the patients a significant bacteriuria was found: e. coli (34.6%), proteus (22.3%), klebsiella (14.6%), citrobacter (9.2%), enterobacter (5.4%) and pseudomonas (5.4%). in testing a high resistance of bacterias to trimethoprim/sulfamethoxazol, ampicillin, and gentamycin was found, whereas good suscep ... | 1992 | 1608185 |
reduction of campylobacter jejuni colonization of chicks by cecum-colonizing bacteria producing anti-c. jejuni metabolites. | cecum-colonizing bacteria were isolated from campylobacter jejuni-free white leghorn (gallus domesticus) laying hens and screened for the ability to produce anti-c. jejuni metabolites. nine isolates were obtained that possessed this characteristic. the peroral administration of the nine isolates as a mixture (ca. 10(9) per chick) to 1-day-old chicks was followed 1 week later by peroral inoculation of campylobacter jejuni (ca. 10(9) per chick) to determine if the cecal isolates could protect chic ... | 1992 | 1610187 |
use of a commercial double-test tablet (rosco pgua/indole) for screening of escherichia coli. | a commercial double-test tablet (rosco pgua/indole) for detection of beta-glucuronidase (beta-gur) activity and indole production was evaluated on a collection of 393 isolates of enterobacteria. both beta-gur and indole were positive on 96.6% of escherichia coli strains. beta-gur, only, was also detected in 25 shigella spp., four enterobacter cloacae, eight citrobacter freundii, and five salmonella enteritidis strains, none of which were indole producers. an additional 261 consecutive clinical i ... | 1992 | 1611844 |
in vitro activity of cefquinome, a new cephalosporin, compared with other cephalosporin antibiotics. | the in vitro activity of cefquinome, a new aminothiazolyl cephalosporin with a c-3 bicyclic pyridinium group, was compared with ceftazidime, cefpirome, and cefepime. cefquinome inhibited members of the enterobacteriaceae at less than or equal to 0.5 microgram/ml for escherichia coli, klebsiella pneumoniae, k. oxytoca, citrobacter diversus, salmonella shigella, proteus mirabilis, morganella, and providencia. although most citrobacter freundii and enterobacter cloacae were inhibited by less than 2 ... | 1992 | 1611848 |
review of the in vitro antibacterial activity of cefprozil, a new oral cephalosporin. | cefprozil is a newer oral cephalosporin with a spectrum of activity against organisms that include gram-positive and gram-negative pathogens. a review of published data shows that cefprozil is active (susceptibility, less than or equal to 8 micrograms/ml; moderate susceptibility, 16 micrograms/ml; resistance, greater than or equal to 32 micrograms/ml) against gram-positive species such as streptococci, methicillin-susceptible staphylococci, and listeria monocytogenes; it may have marginal activi ... | 1992 | 1617037 |
development of resistance during ceftazidime and cefepime therapy in a murine peritonitis model. | resistance emerging after ceftazidime or cefepime therapy was investigated in a peritonitis model. mice were given a peritoneal challenge (10(8) cfu plus talcum) and treated by either antibiotic (50 mg/kg/dose, which produced similar antibiotic concentrations in peritoneal fluid in both cases). after one or three doses, resistance never developed in serratia marcescens or citrobacter freundii infections. after enterobacter cloacae and pseudomonas aeruginosa challenge, ceftazidime selected more r ... | 1992 | 1624394 |
[a case of alveolar hydatid disease of the lung in the kansai district of japan]. | a 78-year-old man was admitted to hospital because of episodes of high grade fever and multiple nodular shadows on chest roentgenogram. he had a past history of percutaneous drainage and partial resection of the left lobe of the liver for liver abscess of unknown origin in 1987. the high grade fever was secondary to sepsis due to citrobacter freundii. the sepsis improved with antibiotic therapy, but the abnormal shadows on chest roentgenogram did not improved. immunoserological tests indicated a ... | 1992 | 1630056 |
[fatal emphysematous pyelonephritis]. | a man aged 46 years with diabetes mellitus was admitted with acute right-sided renal symptoms. pyelonephritis emphysematous without concretions was found. the patient was treated with insulin, fluids, electrolytes and antibiotics and nephrostomy was performed and, subsequently, an internal jj-catheter in the ureter. the symptoms disappeared and he was discharged on a low dosage of sulphamethizol. after the planned removal of the jj-catheter, sepsis running a lethal course developed. this emphasi ... | 1992 | 1631972 |