Publications

the epidemiology of panic symptomatology and agoraphobic avoidance.	in a random community survey of 1,498 urban adults age 18 to 64 years who were interviewed using the diagnostic interview schedule (dis), the lifetime prevalence of panic disorder was 2.2% +/- 0.4%. this was higher in women (3.4% +/- 0.7%) than in men (0.9% +/- 0.6%), and in those under the age of 45 years. lifetime prevalence for panic attacks was 7.8% +/- 0.7%. panic attacks and panic disorder had a similar distribution by age and sex, with higher rates in women than men, and also in the under ...	2009	2788067
neuroprostheses in the management of incontinence in children.		2009	2788362
hierarchy of cytotoxic t cell clones. i. reversal of resistance to lysis and killing between anti-hapten cytotoxic t cells.	cells from clones of anti-hapten cytotoxic t lymphocytes (ctl) can act as both effector cells and, when treated with the specific hapten, as target cells. individual clones can kill haptenated cells only from other clones that are less efficient killers. clones specific for both fluorescein and trinitrophenol could be ordered in a single hierarchy in which resistance to lysis correlated with lytic efficiency. when the killing efficiency was reduced with phorbol myristate acetate (pma) or the col ...	2009	2788518
[new diagnostic criteria for rheumatoid arthritis].		2009	2788569
variceal hemorrhage as a consequence of spontaneous rupture of a pancreatic pseudocyst into the splenic vein.	we describe a case of a 68-yr-old man who died as a consequence of a massive bleed from esophageal varices. at autopsy, a pancreatic pseudocyst that communicated directly with the splenic vein was found. histology confirmed that material from the pseudocyst had embolized to the peripheral portal veins, occluding many of them.	1989	2788993
[duplex and transcranial sonography in the preoperative evaluation of cerebrovascular circulation before heart operations].	fifty unselected patients undergoing open heart surgery (ohs) were examined by duplex and transcranial doppler sonography. two high degree (greater than 75%) carotid stenosis were found in 70 carotid arteries of 35 patients with coronary artery disease. fourteen vessels had unmistakable signs of extracranial vascular disease whilst 54 carotid arteries were identified as normal. two high degree (greater than 75%) carotid stenosis were found in 30 vessels of 15 patients with valvular disease. seve ...	2009	2789209
[duplex and transcranial sonography in the preoperative evaluation of cerebrovascular circulation before heart operations].	fifty unselected patients undergoing open heart surgery (ohs) were examined by duplex and transcranial doppler sonography. two high degree (greater than 75%) carotid stenosis were found in 70 carotid arteries of 35 patients with coronary artery disease. fourteen vessels had unmistakable signs of extracranial vascular disease whilst 54 carotid arteries were identified as normal. two high degree (greater than 75%) carotid stenosis were found in 30 vessels of 15 patients with valvular disease. seve ...	2009	2789209
interleukin 1 in rheumatoid arthritis: potentiation of immune responses within the joint.	specific immunoassays were used to measure il-1 peptides in the serum and synovial fluid of patients with rheumatoid arthritis (ra) and in the serum of age-matched healthy controls. patients with ra had raised levels of both il-1 beta and il-1 alpha in their sera compared to controls. synovial fluid levels of il-1 beta significantly correlated with immunoreactive il-2 and soluble il-2 receptor (sil-2r). in addition, incubation of synovial fluid mnc with human recombinant (hr) il-1 caused a dose- ...	1989	2789325
on suicide statistics.	the classical methodological problem of suicidology is reliability of official statistics. in this article, some recent contributions to the debate, particularly concerning the increased problem of suicide among inuit, are reviewed. secondly the suicide statistics of greenland are analyzed, with the conclusion that the official statistics, as published by the danish board of health, are generally reliable concerning greenland.	2009	2789569
regional pain syndrome.		2009	2790410
[clinical significance of the quantification of obesity. the quetelet index and its use].	the degree of obesity, ie. the quantity of excessive stored adipose tissue, affects substantially morbidity and mortality on cardiovascular, metabolic, and other diseases. while the quantity of an adipose tissue is practically impossible to determine, it is necessary to use the body weight, adjusted for the stature. the quetelet's index (body mass index, bmi) is the best one from height-weight indices. values of bmi define categories of normal weight, overweight, and obesity, which have differen ...	2009	2790909
strand scission in dna induced by quercetin and cu(ii): role of cu(i) and oxygen free radicals.	the naturally occurring flavonoid, quercetin, in the presence of cu(ii) and molecular oxygen caused breakage of calf thymus dna, supercoiled pbr322 plasmid dna and single-stranded m13 phage dna. in the case of the plasmid, the product(s) were relaxed circles or a mixture of these and linear molecules depending upon the conditions. for the breakage reaction, cu(ii) could be replaced by fe(iii) but not by other ions tested [fe(ii), co(ii), ni(ii) and ca(ii)]. structurally related flavonoids, rutin ...	2009	2791202
gallbladder perforation seen on hepatobiliary imaging following morphine sulfate injection.	a case of gallbladder perforation imaged during morphine-augmented cholescintigraphy is presented. tc-99m disida imaging dramatically demonstrated the bile leak. whether morphine sulfate contributed to the perforation of the gallbladder is debatable.	2009	2791419
the homogeneous nature of the hemolytic uremic syndrome.		2009	2791440
estradiol-stimulated increases in uterine eosinophils and nuclear type ii estrogen-binding sites are prevented by pertussis toxin.	previous studies from several laboratories have demonstrated that estradiol treatment resulted in an increase in nuclear type ii binding sites. our previous data suggest that this increase was due to the estradiol-stimulated influx of circulating eosinophils. therefore, we suggested that the uterine nuclear type ii estrogen-binding sites were not of uterine origin. in this report we present further evidence to support this hypothesis. treatment of immature rats with estradiol resulted in the sti ...	1989	2792007
congestive gastropathy and antral varices: is there an association?	gastric mucosal lesions are frequently observed during endoscopy in cirrhotics, but only recently has attention been paid to the gastric mucosal vessels themselves as the cause of such lesions. the presence - observed during endoscopy - of areas of erythema outlined by a yellow mosaic-like network, and the existence - ascertained by histology - of focal ectasia of mucosal vessels are termed "congestive gastropathy". in a prospective investigation of this entity, gastric mucosal biopsies have bee ...	2006	2792012
effects of soft contacts of differing thickness on corneal wound healing in rabbits.	this study was undertaken to determine the effects of thin (60 microns) and thick (240 microns) soft contact lenses of equal water content (70%) and power on nonlesioned and lesioned rabbit corneas. in one group of animals, corneas were not lesioned. thin lenses were placed on left corneas and thick lenses on right corneas. in a second group, lesions were made in both corneas. left corneas were covered with thin lenses and right corneas with thick lenses. post-treatment times were 8 hr and 24 hr ...	1989	2793355
[therapeutic strategy in adrenal tumor].	the therapeutic strategy to be adopted when confronted with an adrenal tumor is schematically presented for the various situations which may occur: --pheochromocytomas, where the principal problems are the blood pressure and the localization and volume of the tumors(s); --conn's syndrome, where a bilateral tumor should not be missed; --cushing's syndrome, where bilateral total adrenalectomy via a posterior approach would seem to be the treatment of choice; --non secreting and secreting adrenal t ...	2009	2794547
detoxification of lithocholic acid. elucidation of the pathways of oxidative metabolism in rat liver microsomes.	the hydroxylation of lithocholic acid (3 alpha-hydroxy-5 beta-cholanoic acid) by adult male sprague-dawley rat liver microsomes supplemented with nadph was studied. metabolites were separated by a combination of thin-layer chromatography and high pressure liquid chromatography, both with and without prior methylation and acetylation of the samples. the resulting products were characterized by thin-layer, gas-liquid, and high pressure liquid chromatography by comparison with authentic bile acid s ...	1989	2794781
inguinal hernia pain. a cause.		2010	2794900
desmoplastic fibroma of the mandible: a case with an unusual clinical presentation.	a new case of desmoplastic fibroma of the mandible is reported. the patient was a 29-year-old woman who presented with a 5-year course of abscess-like lesions simulating a chronic apical infection. radiographically, a nonspecific, small osteolytic area was observed. a wide resection of the tumor and the neighboring bone was performed.	2009	2795301
cranial bone graft harvesting: a modified technique.		2009	2795306
the double-degree debate continues.		2009	2795308
the temporomandibular ligament and the articular eminence as constraints during jaw opening.	it is generally thought that during symmetrical jaw opening the mandible rotates about an axis passing through the centres of the two mandibular condyles, and translates down the articular eminence. the author argues that there are no data to support this assumption. the true combination of movements can only be understood by understanding the constraints that operate during jaw opening and these are the articular eminence and the temporomandibular (tm) ligament. the tm ligament is pulled taut d ...	2009	2795311
consistency, working time and setting time of elastomeric impression materials.	this paper describes the development of an instrument for determining consistency, working time and setting time of elastomeric impression materials. the operating principle involves the application of a fixed compressive strain and the resulting stress is measured. this instrument has been called a comprheometer. temperature control is achieved by water circulation so that simulated room or open-mouth temperatures can be used. values of consistency and working time are presented for a range of ...	2009	2795312
[osteolytic foci: cancer or not?].		2009	2797229
issues affecting the future of dentistry.		2010	2797616
low-dose aspirin in pregnancy.	in a prospective study, we evaluated the effects of low-dose aspirin on maternal and neonatal plasma 6-keto-prostaglandin (pg) f1 alpha concentration, platelet aggregation, platelet thromboxane production, and neonatal transitional circulation. forty women, at a mean (+/- sd) of 37 +/- 2 weeks' gestation, were randomized to receive (n = 10 each) placebo or 20, 60, or 80 mg of aspirin per day until delivery. maternal serum 6-keto-pgf1 alpha levels were not affected by these doses of aspirin, wher ...	2010	2797631
non-contiguous regions of z-dna in a dna dodecamer.	the conformation of the self-complimentary dna dodecamer d(br5cgbr5cgaattbr5cgbr5cg) has been investigated in a variety of salt and solvent conditions by one and two-dimensional 1h nmr. in low salt aqueous solutions, the molecule forms a regular b-dna structure similar to the unmodified dodecamer. however, in aqueous solution containing high salt concentration and methanol, the dodecamer adopts a structure in which the br5cgbr5cg ends of the molecule are in a z-dna like conformation and the aatt ...	2009	2798135
meta-analysis: appropriate tool for the integration of nursing research?		2009	2798158
public perceptions of nursing.		2009	2798174
public perceptions of nursing.		2009	2798174
surgical closure of aorto-pulmonary window without cardiopulmonary bypass.	the surgical treatment of aorto-pulmonary window by a closed technique is described. this avoids the increased risks of extracorporeal circulation and deep hypothermia with or without total circulatory arrest in the neonate or very sick infant.	2009	2798193
surgical closure of aorto-pulmonary window without cardiopulmonary bypass.	the surgical treatment of aorto-pulmonary window by a closed technique is described. this avoids the increased risks of extracorporeal circulation and deep hypothermia with or without total circulatory arrest in the neonate or very sick infant.	2009	2798193
[non-enzymatic protein glycosylation and its clinico-biological significance].		2010	2798209
congenital ciliary aplasia in two siblings. a primitive disregulation of ciliogenesis?	congenital ciliary aplasia was demonstrated in two siblings with clinical history of primary ciliary dyskinesia. ultrastructural histochemistry of successive bronchial biopsies revealed the predominance of immature mucous cells and the total absence of ciliated or preciliated cells in the respiratory epithelium. this original disorder may represent a unique variant of primary ciliary dyskinesia with primitive disregulation of ciliogenesis.	2009	2798216
congenital ciliary aplasia in two siblings. a primitive disregulation of ciliogenesis?	congenital ciliary aplasia was demonstrated in two siblings with clinical history of primary ciliary dyskinesia. ultrastructural histochemistry of successive bronchial biopsies revealed the predominance of immature mucous cells and the total absence of ciliated or preciliated cells in the respiratory epithelium. this original disorder may represent a unique variant of primary ciliary dyskinesia with primitive disregulation of ciliogenesis.	2009	2798216
incidence and prognostic significance of lymphatic and vascular invasion in radical prostatectomy specimens.	a review of 55 radical prostatectomy specimens from patients with clinically localized carcinoma of the prostate was performed. blinded review of slides was performed by a single pathologist and urologist. criteria for invasion were encroachment by tumor of the lymphatic or vascular lumen and evidence of reaction around or in the lymphatic or vascular channel. notation was made of the degree and location of lymphatic and vascular invasion. all patients had a minimum of 5 years of follow-up. twen ...	2009	2798232
incidence and prognostic significance of lymphatic and vascular invasion in radical prostatectomy specimens.	a review of 55 radical prostatectomy specimens from patients with clinically localized carcinoma of the prostate was performed. blinded review of slides was performed by a single pathologist and urologist. criteria for invasion were encroachment by tumor of the lymphatic or vascular lumen and evidence of reaction around or in the lymphatic or vascular channel. notation was made of the degree and location of lymphatic and vascular invasion. all patients had a minimum of 5 years of follow-up. twen ...	2009	2798232
early clinical results of the ttap acetabular cup.	one hundred seventy-five threaded titanium alloy prostheses (ttap) acetabular cups and 125 cemented cups were evaluated clinically and radiographically at 1 to 3 years postoperatively. the series was statistically different in that there were more women in the cemented group than in the non-cemented group (p less than .001). the cemented group was also older than the threaded group (p less than .001). pain, ambulation, function, range of motion, and roentgenograms were evaluated in all patients. ...	2009	2798250
early clinical results of the ttap acetabular cup.	one hundred seventy-five threaded titanium alloy prostheses (ttap) acetabular cups and 125 cemented cups were evaluated clinically and radiographically at 1 to 3 years postoperatively. the series was statistically different in that there were more women in the cemented group than in the non-cemented group (p less than .001). the cemented group was also older than the threaded group (p less than .001). pain, ambulation, function, range of motion, and roentgenograms were evaluated in all patients. ...	2009	2798250
placental weights of normal and aneuploid early human fetuses.	placental and body weights were plotted for 252 normal human fetuses less than 600 gm and mean regressions and 95% prediction intervals were calculated. placentas from 62 aneuploid fetuses were compared to these standards. placenta to body weight ratios from 34 trisomy-21 fetuses were not reduced but those from 15 trisomy-18 fetuses were generally decreased. one of 5 trisomy-13 ratios was below the prediction interval. among 7 triploid fetuses the ratios were above the normal interval in 3 and b ...	1989	2798268
placental weights of normal and aneuploid early human fetuses.	placental and body weights were plotted for 252 normal human fetuses less than 600 gm and mean regressions and 95% prediction intervals were calculated. placentas from 62 aneuploid fetuses were compared to these standards. placenta to body weight ratios from 34 trisomy-21 fetuses were not reduced but those from 15 trisomy-18 fetuses were generally decreased. one of 5 trisomy-13 ratios was below the prediction interval. among 7 triploid fetuses the ratios were above the normal interval in 3 and b ...	1989	2798268
31p-nmr study on intracellular energy transport in muscle.		2009	2798486
31p-nmr study on intracellular energy transport in muscle.		2009	2798486
[personal experience in the diagnosis and therapy of boerhaave's syndrome].	at the surgical clinic of the faculty hospital in hradec králové during the last 20 years 32 patients with perforation of the oesophagus were treated. of these five had a spontaneous rupture of the oesophagus--boerhaave's syndrome. the authors describe their own experience with the diagnosis of this syndrome. they emphasize the importance of early diagnosis which determines the type of surgical treatment, makes a more radical operation possible, reduces the percentage of complications and thus a ...	2010	2799554
[successful therapy of acute post-traumatic hepatic insufficiency using massive doses of corticosteroids].		2007	2800168
regional distribution and behavior of the subcutaneous tissue concerning selection and indication for liposuction.	the distribution of the fat tissue in the subcutaneous layer is described. since it has specific characteristics in each region of the human body, careful evaluation of the distribution before selecting patients for surgery is necessary. the subcutaneous tissue after an operation frequently demonstrates a thick and hard fibrosis which is evidence that liposuction should be performed in the lamellar layers. this type of fibrotic tissue in the subcutaneous areola layer often brings on irregulariti ...	1989	2801296
regional distribution and behavior of the subcutaneous tissue concerning selection and indication for liposuction.	the distribution of the fat tissue in the subcutaneous layer is described. since it has specific characteristics in each region of the human body, careful evaluation of the distribution before selecting patients for surgery is necessary. the subcutaneous tissue after an operation frequently demonstrates a thick and hard fibrosis which is evidence that liposuction should be performed in the lamellar layers. this type of fibrotic tissue in the subcutaneous areola layer often brings on irregulariti ...	1989	2801296
[long ureteral polyp: a case report].	a case of long ureteral polyp is presented. the patient was a 62-year-old woman complaining of asymptomatic macrohematuria. radiological examinations revealed ureteral tumor. a tumor was found with cystoendoscopy, and by transurethral biopsy in bladder the tumor was not malignant. polypectomy was performed. the tumor removed was fibrous polyp measuring about 8 cm in length.	2009	2801413
presence of cytoadhesins (iib-iiia-like glycoproteins) on human metastatic melanomas but not on benign melanocytes.	glycoproteins iib and iiia, a heterodimer complex, play a vital role in blood platelet aggregation and are members of a wide family of membrane receptors known as integrins or cytoadhesins. cellular interaction to extracellular matrix (ecm) adhesive proteins is mediated by integrins. certain tumor cells are known to interact with ecm and blood platelets in the process of metastasis. however, it is not known if tumor cells, compared with their normal counterparts, acquire iib-iiia-like receptors ...	1989	2801613
chronic manganese intoxication.	we report six cases of chronic manganese intoxication in workers at a ferromanganese factory in taiwan. diagnosis was confirmed by assessing increased manganese concentrations in the blood, scalp, and pubic hair. in addition, increased manganese levels in the environmental air were established. the patients showed a bradykinetic-rigid syndrome indistinguishable from parkinson's disease that responded to treatment with levodopa.	2007	2803069
retinal hemorrhage predicts neurologic injury in the shaken baby syndrome.	shaken baby syndrome consists of intracranial and intraocular hemorrhage in the absence of signs of direct trauma in infants who have sustained whiplash/shaking injuries. we evaluated 14 consecutive cases of presumed shaken baby syndrome seen at the university of michigan hospitals, ann arbor, between august 1983 and march 1988, to determine if the severity of retinal hemorrhage was predictive of the severity of acute neurologic injury. the severity of retinal hemorrhage was based on the type an ...	2009	2803095
[developmental characteristics of the beta waves of eeg in normal healthy children].	by the use of an autoregressive (ar) model, development of beta-waves in quantitative eeg parameters was studied in 1,340 normal children aged from 3 to 12 years. the results were summarized as follows. the beta band(13.5-25 hz) was divided into three frequency ranges; beta-1(13.5-17.4 hz), beta-2(17.5-21.4 hz) and beta-3 (21.5-25 hz) waves. the average power and percent-power of the beta-1 and beta-2 waves increased with advancing age, whereas these of the beta-3 wave showed no change with adva ...	2009	2803792
correlates of certification in family medicine in the billing patterns of ontario general practitioners.	there is conflicting evidence as to whether physicians who are certified in family medicine practise differently from their noncertified colleagues and what those differences are. we examined the extent to which certification in family medicine is associated with differences in the practice patterns of primary care physicians as reflected in their billing patterns. billing data for 1986 were obtained from the ontario health insurance plan for 269 certified physicians and 375 noncertified physici ...	2008	2804847
prevention of rectal cancer induced by n-nitrosobis(2-oxopropyl)-amine by exogenous testosterone in mrc rats.	rectal carcinogenicity of n-nitrosobis(2-oxopropyl)amine (bop) in male mrc wistar rats was shown to be inhibited by exogenous testosterone (t) when the hormone was given during, but not after, administration of the carcinogen. this effect was independent of the dose and frequency of bop, which was given either weekly for 20 weeks orally or daily for 3 days subcutaneously. since, except for prostatic cancer, the incidence and the patterns of other bop-induced tumors were not altered by t, this ho ...	1989	2805225
prevention of rectal cancer induced by n-nitrosobis(2-oxopropyl)-amine by exogenous testosterone in mrc rats.	rectal carcinogenicity of n-nitrosobis(2-oxopropyl)amine (bop) in male mrc wistar rats was shown to be inhibited by exogenous testosterone (t) when the hormone was given during, but not after, administration of the carcinogen. this effect was independent of the dose and frequency of bop, which was given either weekly for 20 weeks orally or daily for 3 days subcutaneously. since, except for prostatic cancer, the incidence and the patterns of other bop-induced tumors were not altered by t, this ho ...	1989	2805225
the socioeconomic problems of chronic renal failure: what can we do about them?		2009	2805695
purification of a vasodilator-regulated phosphoprotein from human platelets.	cyclic-nucleotide-elevating vasodilators such as prostaglandin e1, prostacyclin, sodium nitroprusside and endothelium-derived relaxing factor inhibit both contraction of vascular smooth muscle cells and the aggregation of platelets at an early step of the activation cascade. previous studies from this laboratory [waldmann, r., nieberding, m. and walter, u. (1987) eur. j. biochem. 167, 441-448) established that in human platelets cyclic-nucleotide-elevating vasodilators stimulated a pattern of pr ...	1989	2806262
a retrospective study of acute plasma exchange in severe intravascular hemolysis.		2009	2806482
training inspiratory resistance in duchenne dystrophy using adapted computer games.	computer games were modified to encourage respiratory effort by two groups of patients with duchenne muscular dystrophy. one group trained during the first six months of the study, the other during the second six months. inspiratory effort was increased by their having to breathe through a mask to both start and continue the games. pulmonary function tests were done at the beginning of the trial and six, 12 and 18 months later, when forced vital capacity, respiratory muscle endurance and strengt ...	2009	2806735
training inspiratory resistance in duchenne dystrophy using adapted computer games.	computer games were modified to encourage respiratory effort by two groups of patients with duchenne muscular dystrophy. one group trained during the first six months of the study, the other during the second six months. inspiratory effort was increased by their having to breathe through a mask to both start and continue the games. pulmonary function tests were done at the beginning of the trial and six, 12 and 18 months later, when forced vital capacity, respiratory muscle endurance and strengt ...	2009	2806735
carbohydrate structures of nonspecific cross-reacting antigen-2, a glycoprotein purified from meconium as an antigen cross-reacting with anticarcinoembryonic antigen antibody. occurrence of complex-type sugar chains with the gal beta 1----3glcnac beta 1----3gal beta 1----4glcnac beta 1----outer chains.	nonspecific cross-reacting antigen-2 (nca-2) is a glycoprotein purified from meconium as a closely correlated entity with carcinoembryonic antigen (cea). as in the case of cea, only asparagine-linked sugar chains are included in nca-2. in order to elucidate the structural characteristics of the sugar chains of nca-2, they were quantitatively released from the polypeptide backbone by hydrazinolysis and reduced with nab3h4 after n-acetylation. the radioactive oligosaccharides were fractionated by ...	2010	2808357
binaural speech intelligibility in noise for hearing-impaired listeners.	the effect of head-induced interaural time delay (itd) and interaural level differences (ild) on binaural speech intelligibility in noise was studied for listeners with symmetrical and asymmetrical sensorineural hearing losses. the material, recorded with a kemar manikin in an anechoic room, consisted of speech, presented from the front (0 degree), and noise, presented at azimuths of 0 degree, 30 degrees, and 90 degrees. derived noise signals, containing either only itd or only ild, were generat ...	2009	2808911
binaural speech intelligibility in noise for hearing-impaired listeners.	the effect of head-induced interaural time delay (itd) and interaural level differences (ild) on binaural speech intelligibility in noise was studied for listeners with symmetrical and asymmetrical sensorineural hearing losses. the material, recorded with a kemar manikin in an anechoic room, consisted of speech, presented from the front (0 degree), and noise, presented at azimuths of 0 degree, 30 degrees, and 90 degrees. derived noise signals, containing either only itd or only ild, were generat ...	2009	2808911
biological application of high voltage electron microscopy.		1998	2809473
spontaneous expulsion of a large submucosal colonic lipoma.		2009	2810300
from the centers for disease control. eosinophilia-myalgia syndrome--new mexico.		2007	2810660
"a few bad apples?".		2009	2812134
"a few bad apples?".		2009	2812134
sleep apnea in alzheimer's disease.	mental deterioration accompanying sleep apnea has been noted frequently. because sleep apnea increases with age, such deficits raise the possibility that dementia in the elderly could be related to sleep apnea. in this study we investigated this possibility cross-sectionally by comparing respiration during sleep in 28 patients with alzheimer's disease (ad) and 25 nondemented controls. we hypothesized that higher levels of sleep apnea would be present in ad patients. our results indicated no sign ...	2009	2812195
sleep apnea in alzheimer's disease.	mental deterioration accompanying sleep apnea has been noted frequently. because sleep apnea increases with age, such deficits raise the possibility that dementia in the elderly could be related to sleep apnea. in this study we investigated this possibility cross-sectionally by comparing respiration during sleep in 28 patients with alzheimer's disease (ad) and 25 nondemented controls. we hypothesized that higher levels of sleep apnea would be present in ad patients. our results indicated no sign ...	2009	2812195
heterogeneity in alzheimer's disease.	the phenotype of alzheimer's disease is variable. age of onset, cognitive features, and neuropathology differ case to case. in some cases the differences are due to variable expression and others to genetic heterogeneity. present evidence suggests four types of alzheimer's disease: early and late onset autosomal dominant forms, trisomy 21, and phenocopies.	2009	2812203
heterogeneity in alzheimer's disease.	the phenotype of alzheimer's disease is variable. age of onset, cognitive features, and neuropathology differ case to case. in some cases the differences are due to variable expression and others to genetic heterogeneity. present evidence suggests four types of alzheimer's disease: early and late onset autosomal dominant forms, trisomy 21, and phenocopies.	2009	2812203
genetics and alzheimer's disease: notes of an environment watcher (with apologies to l. thomas).	support has recently been voiced for the genetic hypothesis of alzheimer's disease; frequently at the expense of considerations of environmental factors. in the adult, genetic diseases rarely exist without modification by environment forces. atherosclerosis leading to myocardial infarction may provide a useful model to consider genetic and environmental factors in alzheimer's disease. familial hypercholesterolemia produces a premature inherited form of myocardial infarction, whereas, atheroscler ...	2009	2812210
genetics and alzheimer's disease: notes of an environment watcher (with apologies to l. thomas).	support has recently been voiced for the genetic hypothesis of alzheimer's disease; frequently at the expense of considerations of environmental factors. in the adult, genetic diseases rarely exist without modification by environment forces. atherosclerosis leading to myocardial infarction may provide a useful model to consider genetic and environmental factors in alzheimer's disease. familial hypercholesterolemia produces a premature inherited form of myocardial infarction, whereas, atheroscler ...	2009	2812210
[intraoperative monitoring of cerebral function and carotid hemodynamics during carotid endarterectomy].	the authors investigated the hemodynamics and monitored the cerebral function to perform the carotid endarterectomy (cea) safely. the hemodynamics were investigated by measurements of carotid arterial blood flow by an electromagnetic flow meter before and after cea. and a doppler flow meter applied directly to the carotid arteries to analyze the flow parameters such as peak frequencies (pf), mean frequencies (mf), mode frequencies (mo f) and % window. we used routinely our specially designed shu ...	2009	2812257
[intraoperative monitoring of cerebral function and carotid hemodynamics during carotid endarterectomy].	the authors investigated the hemodynamics and monitored the cerebral function to perform the carotid endarterectomy (cea) safely. the hemodynamics were investigated by measurements of carotid arterial blood flow by an electromagnetic flow meter before and after cea. and a doppler flow meter applied directly to the carotid arteries to analyze the flow parameters such as peak frequencies (pf), mean frequencies (mf), mode frequencies (mo f) and % window. we used routinely our specially designed shu ...	2009	2812257
the venoarteriolar reflex in diabetic and other neuropathies.	limb dependency activates the venoarteriolar reflex (var), resulting in reflex vasoconstriction (rv). since others have reported the var to fail in diabetic neuropathy, we examined the reliability of this test in detecting sympathetic failure in diabetic and other neuropathies. we studied 40 controls, 49 diabetic subjects, and 29 patients with other neuropathies. the mean rv was greater in controls than in diabetics or other neuropathies, but there were marked overlaps among groups. we conclude ...	2009	2812329
the venoarteriolar reflex in diabetic and other neuropathies.	limb dependency activates the venoarteriolar reflex (var), resulting in reflex vasoconstriction (rv). since others have reported the var to fail in diabetic neuropathy, we examined the reliability of this test in detecting sympathetic failure in diabetic and other neuropathies. we studied 40 controls, 49 diabetic subjects, and 29 patients with other neuropathies. the mean rv was greater in controls than in diabetics or other neuropathies, but there were marked overlaps among groups. we conclude ...	2009	2812329
feeding problems in severely demented patients seen from task and relationship aspects.	this study aimed at increasing the understanding of feeding problems in severely demented patients cared for in a task assignment system. twenty-three video-recordings made during the feeding of 15 severely demented patients and 55 focused interviews with 45 caregivers, who fed the 15 patients during that period were analysed regarding the feeding problems seen from a task aspect and from a relationship aspect. the result indicated that the problems were partly of a more constant nature and part ...	2009	2814080
feeding problems in severely demented patients seen from task and relationship aspects.	this study aimed at increasing the understanding of feeding problems in severely demented patients cared for in a task assignment system. twenty-three video-recordings made during the feeding of 15 severely demented patients and 55 focused interviews with 45 caregivers, who fed the 15 patients during that period were analysed regarding the feeding problems seen from a task aspect and from a relationship aspect. the result indicated that the problems were partly of a more constant nature and part ...	2009	2814080
[exorbitant responsibilities!].		2010	2814197
prognostic and therapeutic observations of manifestations in the genitourinary tract of adenocarcinoma of the colon and rectum.	to evaluate the significance of involvement of the genitourinary tract in adenocarcinoma of the colon and rectum, we received the records of 178 patients with adenocarcinoma of the colon and rectum admitted to the university of massachusetts medical center from 1980 to 1985. sixty-eight patients (38 per cent) had urologic manifestations categorized as ureteral obstruction or injury (34 per cent), invasion to the bladder or prostate, or both (10 per cent), isolated gross hematuria (18 per cent), ...	2010	2814767
[written information on prescribed drugs provided by pharmacies].		2009	2815030
[written information on prescribed drugs provided by pharmacies].		2009	2815030
differential inhibition of downstream gene expression by the cauliflower mosaic virus 35s rna leader.	the effect of the 600 nucleotide-long camv 35s rna 5' leader sequence on the expression of downstream genes was analyzed both in plant protoplasts and in vitro. for transient expression studies in protoplasts derived from host and nonhost plants, the bacterial chloramphenicol acetyl transferase (cat) gene was fused to the initiation codon of orf vii. the leader sequence reduced cat expression two- to four-fold in protoplasts derived from three host species, but 10- to 50-fold in protoplasts deri ...	1989	2815595
differential inhibition of downstream gene expression by the cauliflower mosaic virus 35s rna leader.	the effect of the 600 nucleotide-long camv 35s rna 5' leader sequence on the expression of downstream genes was analyzed both in plant protoplasts and in vitro. for transient expression studies in protoplasts derived from host and nonhost plants, the bacterial chloramphenicol acetyl transferase (cat) gene was fused to the initiation codon of orf vii. the leader sequence reduced cat expression two- to four-fold in protoplasts derived from three host species, but 10- to 50-fold in protoplasts deri ...	1989	2815595
is a rise in [ca]1 responsible for rapid changes in neuronal excitability, ca currents, extracellular ions and ph0 induced by brief anoxia?		2006	2816423
is a rise in [ca]1 responsible for rapid changes in neuronal excitability, ca currents, extracellular ions and ph0 induced by brief anoxia?		2006	2816423
[study on the interactions during storage of compounds of the antacid group. i. interactions of the components in suspensions].	twenty antacid mixtures of six quality groups containing al(oh)3, gel, mg(oh)2, mg2si3o8, caco3 and naal(oh)2co3 at different ratios were prepared and stored for 150 days at 20 degrees c in the form of aqueous suspensions. changes of ph in the suspensions were measured, and the accompanying structural changes were examined by ir spectrometry and x-ray diffraction analysis. hydrotalcite was found to be formed during storage of aqueous suspensions of mixtures of al(oh)3 mg(oh)2; al(oh)3: mg(oh)2: ...	2009	2816464
the measurement of secretory endometrial protein pp14 in serum from postmenopausal women receiving unopposed estrogen or continuously combined estrogen/progestogen.	a highly sensitive radioimmunoassay was developed to measure the low serum concentrations of the endometrial secretory placenta protein 14 (pp14) in postmenopausal women. the assay was established by selecting optimum reaction conditions for radioactive labelling of pp14, combined with simple procedures for the purification of the labelled pp14. the pp14 assay was used in 2 groups of healthy, early postmenopausal women blindly receiving either estrogen monotherapy (n = 20, placebo n = 25) or con ...	1989	2816479
[characteristics of the course of the gestation period in patients with solitary kidney].	clinical biochemical, bacteriological investigations and functional tests were performed in 37 pregnant females with a solitary kidney. the status of fetoplacental system was studied as well. the investigators noted such common complications of pregnancy as the aggravation of renal inflammation, a high rate of caesarean section and postnatal morbidity. it was concluded that in case of pyelonephritic affection a solitary kidney the pregnancy should be terminated. if the infection was absent and t ...	2009	2817278
on the estimation of pulmonary capillary pressure from arterial occlusion.	we have attempted to evaluate some approaches for estimating pulmonary capillary pressure from the transient pressure data obtained from the tip of the swanz-ganz catheter after inflation of the balloon. to this end experiments were carried out in anesthetized dogs in which pulmonary vasoconstriction was induced by infusion of histamine, serotonin, or norepinephrine or by hypoxia. in a group of closed chest dogs, the time course for the fall in the catheter tip pressure toward the wedge pressure ...	1989	2817586
[visualization of forensically important foreign bodies by direct roentgen magnification].	the detection of foreign bodies of microscopic dimensions with radiographic techniques is limited by the size and density of the particle and the radiographic resolution. these restrictions can be of decisive value in case work. the high grade direct radiographic magnification technique was successfully used in preceding experiments. due to its 1 mu focal spot, this tube allows direct magnifications up to 250 times. in present studies, the advantages as well as the limitations of this new techni ...	1989	2818477
[visualization of forensically important foreign bodies by direct roentgen magnification].	the detection of foreign bodies of microscopic dimensions with radiographic techniques is limited by the size and density of the particle and the radiographic resolution. these restrictions can be of decisive value in case work. the high grade direct radiographic magnification technique was successfully used in preceding experiments. due to its 1 mu focal spot, this tube allows direct magnifications up to 250 times. in present studies, the advantages as well as the limitations of this new techni ...	1989	2818477
[production of variable high pressure pulses in the area of therapeutic ultrasound].		2009	2819136
identification of recessive mutations at human cancer loci.		1987	2820528
in vivo measurements of tissue ph of the heart, brain, liver, spleen, and skeletal muscle following therapy of severe metabolic uraemic acidosis with infusion of bases: an experimental study on the limitation of the mellemgaard-astrup equation.	the intracellular tissue ph of the heart, brain, liver, spleen, and skeletal muscle of nephrectomized rats was determined in vivo from the distribution of 14c-labelled dmo (5,5-dimethyl-2-4-oxazolidinedione) following acute variation of arterial plasma ph (phe) by co2 inhalation or sodium bicarbonate administration in the range of phe 6.9-7.7, or following correction of severe metabolic uraemic acidosis with sodium bicarbonate or tris (hydroxymethyl) aminomethane (tham) infusion according to the ...	1987	2820724
atp synthesis by the (na+ + k+)-atpase in the absence of an ionic gradient. effects of organic solvent.	a 200-fold decrease in the pi concentration required for half-maximal phosphorylation of the (na+ + k+)-atpase is observed when 40% (v/v) dimethyl sulfoxide is added to the assay medium. the phosphoenzyme formed in the presence of dimethyl sulfoxide is able to transfer its phosphate to to form atp when concentrations of organic solvent and of na+, and is inhibited by ouabain.	1987	2820794