Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| brucella evades macrophage killing via virb-dependent sustained interactions with the endoplasmic reticulum. | the intracellular pathogen brucella is the causative agent of brucellosis, a worldwide zoonosis that affects mammals, including humans. essential to brucella virulence is its ability to survive and replicate inside host macrophages, yet the underlying mechanisms and the nature of the replicative compartment remain unclear. here we show in a model of brucella abortus infection of murine bone marrow-derived macrophages that a fraction of the bacteria that survive an initial macrophage killing proc ... | 2003 | 12925673 |
| [genetic variability of bordetella pertussis strains. part i. current knowledge]. | variability of b. pertussis genome concerning s1 subunit of pertussis toxin (ptxs1) and pertactin (prn) genes has recently been recognised. studies clearly showed differences in the dna patterns and ptxs1 and prn alleles present in b. pertussis strains used for production of pertussis component in the dtp vaccine, in comparison to strains presently isolated from clinical materials. this trend has been observed in highly immunized populations with a long history of pertussis vaccination (the neth ... | 2003 | 12926327 |
| [genetic variability of bordetella pertussis strains. part ii. perspectives]. | in some highly immunized countries with long history of pertussis vaccination (the netherlands, finland, poland, usa, france, great britain) differences in the dna patterns and ptxs1 and prn alleles present in b. pertussis strains used for production of pertussis component in the dtp vaccine, in comparison to strains presently isolated from clinical materials have been found. studies on efficacy of whole-cell and acellular pertussis vaccines in elimination of b. pertussis strains harbouring diff ... | 2003 | 12926328 |
| bordetella pertussis acquires resistance to complement-mediated killing in vivo. | in order to initially colonize a host, bacteria must avoid various components of the innate immune system, one of which is complement. the genus bordetella includes three closely related species that differ in their ability to resist complement-mediated killing. bordetella parapertussis and bordetella bronchiseptica resist killing in naïve serum, a characteristic that may aid in efficient respiratory tract colonization and has been attributed to expression of o antigen. bordetella pertussis lack ... | 2003 | 12933835 |
| crucial role of antibodies to pertactin in bordetella pertussis immunity. | pertussis, a serious infectious disease of the respiratory tract caused by bordetella pertussis, is reemerging in vaccinated populations. efforts to curtail this disease are hampered by limited insight into the basis of protective immunity. opsonophagocytosis was recently found to play a central role in cellular bactericidal activity against b. pertussis. in the present study, we studied the specificity of opsonic antibodies. anti-pertactin antibodies, but not anti-pertussis toxin, anti-fimbriae ... | 2003 | 12934190 |
| role of nuclear factor-kappa b in the regulation of intercellular adhesion molecule 1 after infection of human bronchial epithelial cells by bordetella pertussis. | previous work has demonstrated that infection of human bronchial epithelial cells by bordetella pertussis up-regulates intercellular adhesion molecule-1 (icam-1) gene and protein expression. it has also been shown that interaction of the arg-gly-asp (rgd) site of filamentous hemagglutinin (fha) with host cell very late antigen (vla)-5 (alpha 5 beta 1 integrin) is required for the up-regulation of epithelial icam-1 expression, and that pertussis toxin (pt) impairs this response. we therefore exam ... | 2003 | 12946329 |
| in vitro selection for enzymatic activity: a model study using adenylate cyclase. | an in vitro enzyme selection that can, in principle, be generalised to most chemical reactions, is described. it makes use of filamentous phage display and of a tailor-made antibody fragment directed against the reaction product. the conversion of atp into 3',5'-cyclic amp catalysed by bordetella pertussis adenylate cyclase is taken as an example. | 2003 | 12946341 |
| identification and characterization of the last two unknown genes, dapc and dapf, in the succinylase branch of the l-lysine biosynthesis of corynebacterium glutamicum. | the inspection of the complete genome sequence of corynebacterium glutamicum atcc 13032 led to the identification of dapc and dapf, the last two unknown genes of the succinylase branch of the l-lysine biosynthesis. the deduced dapf protein of c. glutamicum is characterized by a two-domain structure and a conserved diaminopimelate (dap) epimerase signature. overexpression of dapf resulted in an 8-fold increase of the specific epimerase activity. a defined deletion in the dapf gene led to a reduce ... | 2003 | 12948639 |
| the host response to anthrax lethal toxin: unexpected observations. | bacillus anthracis, the causative agent of anthrax, is believed to induce disease and death in humans in an endotoxic shock-like manner. a comprehensive study of the effects of anthrax toxin in mice demonstrates that toxin-induced death is mediated not by cytokine release, as previously thought, but by hypoxia-induced liver failure. the study strongly suggests that the therapies developed for treatment of cytokine-mediated septic shock will not be appropriate for the treatment of anthrax. | 2003 | 12952914 |
| development and clinical evaluation of an internally controlled, single-tube multiplex real-time pcr assay for detection of legionella pneumophila and other legionella species. | a multiplex real-time pcr assay for detection of legionella pneumophila and legionella spp. and including an internal control was designed. legionella species, l. pneumophila, and the internal control were detected simultaneously by probes labeled with 6-carboxy-fluorescein, hexachlorofluorescein, and indodicarbocyanine, respectively. therefore, no postamplification analysis was required in order to distinguish the targets. the sensitivity of both assays was 2.5 cfu/ml, and from analysis of 10 c ... | 2003 | 12958219 |
| evaluation of real-time pcr for detection of and discrimination between bordetella pertussis, bordetella parapertussis, and bordetella holmesii for clinical diagnosis. | pcr is increasingly being used as a diagnostic test for the detection of bordetella pertussis and bordetella parapertussis dna, as it has improved sensitivity and specificity in comparison to conventional techniques. the assay described here uses the two insertion sequences is481 and is1001 for b. pertussis and b. parapertussis, respectively, with detection by molecular beacons. the real-time pcr for is481 detects both b. pertussis and bordetella holmesii, and the real-time pcr for is1001 detect ... | 2003 | 12958235 |
| toll-like receptor 4-mediated innate il-10 activates antigen-specific regulatory t cells and confers resistance to bordetella pertussis by inhibiting inflammatory pathology. | signaling through toll-like receptors (tlr) activates dendritic cell (dc) maturation and il-12 production, which directs the induction of th1 cells. we found that the production of il-10, in addition to inflammatory cytokines and chemokines, was significantly reduced in dcs from tlr4-defective c3h/hej mice in response to bordetella pertussis. tlr4 was also required for b. pertussis lps-induced maturation of dcs, but other b. pertussis components stimulated dc maturation independently of tlr4. th ... | 2003 | 12960338 |
| preventing infectious diseases during and after international adoption. | families of internationally adopted children face risks associated with travel if they pick up their children overseas. unlike other travelers, they also face risks because of close contact with a child with uncertain infection and vaccination status. tuberculosis organisms, hepatitis a virus, hepatitis b virus, and measles virus have been transmitted from adopted children to family and community members. intestinal parasites, bordetella pertussis, and other infectious disease agents can also be ... | 2003 | 12965946 |
| ancient origin of the tryptophan operon and the dynamics of evolutionary change. | the seven conserved enzymatic domains required for tryptophan (trp) biosynthesis are encoded in seven genetic regions that are organized differently (whole-pathway operons, multiple partial-pathway operons, and dispersed genes) in prokaryotes. a comparative bioinformatics evaluation of the conservation and organization of the genes of trp biosynthesis in prokaryotic operons should serve as an excellent model for assessing the feasibility of predicting the evolutionary histories of genes and oper ... | 2003 | 12966138 |
| diagnosis and treatment of multiple sclerosis and amyotrophic lateral sclerosis: neuropathies from bordetella pertussis. | having found positive the research for anti-bordetella antibodies in the 95.47% of 92 patients affected by defined multiple sclerosis and in the 100% of 55 patients affected by non-patched neuropathies (amyotrophic lateral sclerosis and correlated neuropathies), i reassessed the pathogenesis of the neuropathies from bordetella pertussis. in the two categories of neuropathies (with and without patches), the beginning pathogenetic mechanisms are the same: 1) pertussis re-infection in patients with ... | 2003 | 12975723 |
| [serological affinity between h. pertussis and h. parapertussis]. | 1952 | 12978043 | |
| [antigenic structure of hemophilis pertussis]. | 1952 | 13004821 | |
| the inability of the capsular material of haemophilus pertussis to produce protective antisera. | 1952 | 13011268 | |
| on a semisynthetic fluid medium for the growth of hemophilus pertussis. | 1952 | 13011891 | |
| [the agglutinogen function of hemophilus pertussis]. | 1952 | 13015080 | |
| production, extraction and purification of haemagglutinin of haemophilus pertussis. | 1952 | 13022907 | |
| on the protective antigen of phase 1 h. pertussis. | 1952 | 13029568 | |
| some observations made during experiments on mice inoculated with h. pertussis. | 1952 | 13030216 | |
| the active immunization of mice against an intracerebral infection of haemophilus pertussis organisms by intranasal instillation of h. pertussis antigens. | 1953 | 13035052 | |
| three-dimensional patterns of antigenic modulation of haemophilus pertussis, h. parapertussis and h. bronchisepticus. | 1953 | 13035053 | |
| the altered reactivity of mice after immunization with hemophilus pertussis vaccine. | 1953 | 13035134 | |
| histamine sensitivity and anaphylaxis in the pertussis-vaccinated rat. | 1952 | 13037767 | |
| studies on the antigenic substance of h. pertussis reacting in the complement fixation test. | 1952 | 13039308 | |
| [serologic affinity between h. pertussis, h. parapertussis and br. bronchiseptica]. | 1952 | 13041870 | |
| [study of the sensitivity of 22 strains of hemophilus pertussis to antibiotics]. | 1952 | 13043094 | |
| protective effect of human placental extract on the experimental infection of h. pertussis in mice. | 1952 | 13049890 | |
| studies on the sensitivity of mice to histamine following injection of hemophilus pertussis. i. effect of strain and age of mice. | 1953 | 13061192 | |
| [stimulation with helicidine of biologic mechanisms antagonistic to hemophilus pertussis]. | 1953 | 13065120 | |
| pigment production by haemophilus parapertussis. | 1953 | 13069413 | |
| [bacteria distinct from hemophilus pertussis causing syndromes analogous to whooping cough, and the action in vivo of helicidine on these bacteria]. | 1953 | 13079828 | |
| antigenic relationships of haemophilus pertussis, the parapertussis bacillus, and brucella bronchiseptica as shown by cross protection tests in mice. | 1953 | 13084553 | |
| [paper chromatography in biochemical studies on bacteria; studies on amino acids in hemophilus pertussis]. | 1953 | 13099677 | |
| antigenic hemophilus pertussis vaccines grown on charcoal agar. | 1953 | 13109242 | |
| anaphylactic shock in the mouse vaccinated with hemophilus pertussis. iii. antigens. antibody and passive transfer studies. | 1953 | 13118166 | |
| adrenal function tests in mice sensitized to histamine with hemophilus pertussis vaccine. | 1953 | 13121044 | |
| serological studies on h. pertussis h. parapertussis and h. bronchisepticus. | 1953 | 13123910 | |
| [effect of synthomycetin and of levomycetin on hemophilus pertussis and on its infection]. | 1953 | 13132536 | |
| comparative study of the effect of many basic antibiotics on hoemophilus pertussis and on experimental murine pertussis. | 1953 | 13136150 | |
| [experimental report on the problem of resistance of allergic reaction]. | 1953 | 13137891 | |
| variation of the antigenic structure of certain bacteria with temperature of incubation and ionic composition of the medium. | 1953 | 13140206 | |
| studies on the metabolism of hemophilus pertussis. i. on the metabolic cycle. | 1953 | 13142731 | |
| studies on the metabolism of hemophilus pertussis. ii. on the significance of active charcoal, red cells and soluble starch in the culture medium. | 1953 | 13142732 | |
| studies on the sensitivity of mice to histamine following injection of hemophilus pertussis. ii. effect of various substances upon histamine hypersensitivity. | 1954 | 13142839 | |
| agglutination of bacteria (hemophilus pertussis and salmonella typhosa) in vitro by human blood lymphocytes and cytoplasmic extrusions of lymphocytes. | 1954 | 13143224 | |
| [enhancement by helicidine of biologic antagonistic mechanisms against hemophilus pertussis]. | 1954 | 13147889 | |
| [bacteria differentiated from hemophilus pertussis causing syndrome similar to whooping cough and action in vivo of helicidine on these bacteria]. | 1954 | 13147891 | |
| [effect of vitamin k on hemophilus pertussis]. | 1953 | 13151636 | |
| [experimental studies on the effect of various antibiotics on hemophilus pertussis]. | 1954 | 13157574 | |
| [biology of hemophilus pertussis]. | 1954 | 13157576 | |
| [practical application of casein hydrolysate medium in whooping cough]. | 1954 | 13157577 | |
| [growth of freshly isolated cultures of hemophilus pertussis on casein hydrolysate medium with decreased blood content]. | 1954 | 13157578 | |
| humoral antibodies and intradermal reactions to chemical fractions of hemophilus parapertussis. | 1954 | 13157630 | |
| studies of the hemagglutinin of haemophilus pertussis. | 1953 | 13162659 | |
| protective antigen of haemophilus pertussis. | 1954 | 13164367 | |
| [effects of vitamin k on hemophilus pertussis]. | 1954 | 13166933 | |
| studies on the antigenic relation between h. pertussis. h. parapertussis and br. bronchiseptica with special reference to the complement fixation test. | 1953 | 13175377 | |
| [biological assay of preparations of helix pomatia l..]. | 1954 | 13189202 | |
| the ability of pertussis vaccine to produce in mice specific immunity of a type not associated with antibody production. | 1954 | 13190117 | |
| a selective medium for the primary isolation of haemophilus pertussis and haemophilus para-pertussis. | 1954 | 13192306 | |
| [studies on hemophilus pertussis (bordet-gengou). i. trials for preservation or recovery of the virulence in hemophilus pertussis]. | 1954 | 13206784 | |
| a new selective medium for haemophilus pertussis, containing a diamidine, sodium fluoride and penicillin. | 1954 | 13212033 | |
| [hemolysis in rosettes by hemophilus pertussis and hemophilus parapertussis cultured on bordet-gengou medium]. | 1954 | 13218388 | |
| studies on the k antigen of h pertussis; its existence and a method of detection. | 1954 | 13221349 | |
| the type specificity of haemophilus pertussis. | 1954 | 13221812 | |
| studies on the embden-meyerhof system and the warburg-lipman-dickens pathway of the organisms of pertussis-parapertussis-bronchisepticus group. | 1954 | 13232832 | |
| reactions of cells in tissue culture to hemophilus pertussis. i. effect of whole organisms on brain tissue and results of treatment with specific and normal serum. | 1954 | 13238266 | |
| quantitative studies in diphtheria prophylaxis. antigenic interactions. i. simultaneous inoculations. | 1955 | 13250118 | |
| the nutritional requirements of haemophilus pertussis. | 1955 | 13252205 | |
| demonstration of passive transfer of protective antibodies against h. pertussis earlier than agglutinins are detectable. | 1955 | 13258227 | |
| bacterial allergy increases susceptibility to influenza virus in mice. | 1955 | 13273452 | |
| studies on the k antigen of haemophilus pertussis; especially on the so-called s-antigen. | 1955 | 13278103 | |
| amino acid metabolism in the genus bordetella. | 1955 | 13278505 | |
| [hemophilus pertussis hemagglutinin. i. formation of hemagglutinin in cultures of hemophilus pertussis and its certain properties]. | 1955 | 13282449 | |
| [role of methods of handling and of structure of strains in nature of toxic substances obtained from hemophilus pertussis]. | 1955 | 13282450 | |
| [investigations on toxin of hemophilus pertussis]. | 1955 | 13282451 | |
| [production and certain properties of pertussis endotoxin]. | 1955 | 13282452 | |
| [effect of levomycetin, streptomycin, and preparation no. 16 on multiplication of hemophilus pertussis and on the development of experimental whooping cough in white mice]. | 1955 | 13282453 | |
| [production of pertussis-streptococcal anatoxin]. | 1955 | 13282456 | |
| studies on the indirect hemagglutination test and hemolysis test by erythrocytes sensitized with h. pertussis antigens. 1. | 1953 | 13286893 | |
| the growth requirements of haemophilus pertussis on solid media. | 1955 | 13295920 | |
| studies on the indirect hemagglutination test and hemolysis test by erythrocytes sensitized with h. pertussis antigens. ii. | 1954 | 13296319 | |
| studies on haemophilis pertussis. iii. some properties of each phase of h. pertussis. | 1954 | 13296321 | |
| studies on haemophilus pertussis. iv. preventive potency of each phase organisms of h. pertussis in mice. | 1954 | 13296322 | |
| studies on haemophilus pertussis. v. relation between the phase of bacilli and the progress of the whooping-cough. | 1954 | 13296323 | |
| [hemophilus pertussis and volatile plant drugs]. | 1955 | 13300398 | |
| [hemagglutinin of hemophilus pertussis. ii. characteristics of hemagglutinin extracted from hemophilus pertussis cultures]. | 1955 | 13300900 | |
| [method of preparation of whooping cough vaccines. i. effect of increased aeration on dynamics of multiplication of hemophilus pertussis in fluid medium]. | 1955 | 13300901 | |
| [studies on hemophilus pertussis (border-gengou). iii. coagulase activity in other hemophilus species; comparative studies with micrococcus pyogenes aureus]. | 1955 | 13301721 | |
| [studies on hemophilus pertussis (bordet-gengou). iv. studies on antigenicity, virulence and toxicity]. | 1955 | 13301722 | |
| a soluble antigen of phase 1 hemophilus pertussis. i. mouse protection test of filtrate or supernatant of cultures in a medium without soluble starch or carbon particles. | 1956 | 13306951 | |
| [fluid cultures of hemophilus pertussis. ii. comparative protective properties (in the mouse) of various fractions]. | 1955 | 13311014 | |
| [effects of parabiosis on sensitization to histamine of mice immunized with hemophilus pertussis]. | 1955 | 13317246 | |
| effect of extracts of hemophilus pertussis on leukocyte counts in normal and sensitized mice. | 1956 | 13335322 | |
| production of toxin of phase i hemophilus pertussis in the medium added with anion exchange resin and mouse protection test of culture supernate. | 1955 | 13338325 | |
| [antigenic and immunogenic qualities of various phases of hemophilus pertussis]. | 1956 | 13338793 |