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study of genetic relationships among marine species of the genera beneckea and photobacterium by means of in vitro dna/dna hybridization.strains representative of species of the marine genera beneckea and photobacterium were used as reference standards in in vitro dna/dna competition experiments. within a given species, strains were found to be related by over 80% competition. (competition was defined as the amount of radioactive dna displaced by heterologous dna relative to the amount displaced by homologous dna.) on the basis of interspecies competition values (expressed as averages), the following groupings could be made: 1. " ...19761015934
[inhibiting effect of cholera vibrio neuraminidase in rauscher mouse leukemia].a study was made of the inhibitory effect of neuraminidase of cholera vibrio in mouse rauscher leukemia. it was shown that the processing of cells of the spleen of mice suffering from leukemia with neuraminidase (in a dose of 50 units/ml and more) significantly inhibited the capacity of these cells to induce leukemia in their injection to balb/c mice. in the mentioned concentration neuraminidase injected repeatedly parenterally produced no therapeutic effect in rauscher leukemia.19761016719
antibiotic sensitivity pattern of v. cholerae strains isolated in 1974. 19761017856
[small outbreak of cholera in the province of orense]. 19761019557
adjuvant immunochemotherapy of murine neoplasms. 19761019835
synergistic lymphocyte stimulation to tumor--specific antigens after immunization with modified tumor cells. 19761019838
serological response and serum immunoglobulin levels in volunteers immunized with cholera toxin. 19761022695
[role of local factors of immunity with regard to cholera infection. i. localization and multiplication of vibrios in ligated small intestine loops of non-immunized rabbits and newborn animals]. 19761023438
[improvement in the method of obtaining monospecific sera to soluble antigens]. 19761023445
sensitivity of vibrio group of organisms to minocycline--a new tetracycline derivative. 19761024085
[long-term survival of e1 tor cholera vibrios in naturally contaminated sewage].el tor cholera vibrios of ogava serological type were revealed in the sewage of the locomotive shed for 15 months. in experiment with an oil catcher in naturally infected sewage el tor vibrios survived 36 days, in storage of this sewage at the laboratory--39 days, in the artificially infected sewage of a settlement and of a milk plant--2 and 11 days, respectively, in the oil and disel fuel--14 months. consequently, el tor vibrio can survive in the sewage with a high oil product content for a lon ...19761024446
[phage typing of cholera vibrios with different sets of phages].a comparative study was made of two sets of mukerjee and drozhevkina-arutyunova's bacteriophages in typing 514 strains of the el tor vibrios and 45 strains of clasic biotype. it was shown that the mukerjee or drozhevkina-arutyunova's phages could be used for the typing of cholera vibrios. the phages of the latter set prove to detect more phage types (18 against 11); they determine both the phage type and the biotype at the same time. the typing of cholera vibrios of both biotypes is possible, an ...19761024447
[reactogenicity and immunologic effectiveness of cholerogen-anatoxin. feasibility of revaccination with cholerogen-anatoxin, determination of optimal doses and times for administration].the authors discussed the results of study of the titre of vibration antibodies and antitoxins one, three and five months after the vaccination of adults with an optimal vaccination dose of cholerogen toxoid (24oo bu). comparison of the immunological information obtained at the above mentioned periods showed the expediency of revaccination three months after the vaccination. immunogenicity of the three doses of the cholerogen-toxoid tested (1200, 2400, 3600 bu) displayed no statistically signifi ...19761024451
positional distribution of fatty acids in phosphatidylethanolamine of vibrio cholerae 569 b (inaba) at different growth conditions. 19761024965
comparative studies on the enzymes of different strains of vibrio cholerae & vibrio parahaemolyticus. 19761024973
inhibition of adp-induced platelet aggregation as a possible test for evaluation of the enterotoxigenicity of some enterobacteria. preliminary study].some culture filtrates or enterotoxin preparations from enterobacteria that activate the adenylate cyclase system (vibrio cholerae, lt fraction from escherichia coli and klebsiella pneumoniae, shigella dysenteriae type 1) exibit an inhibiting effect on adp-induced platelet aggregation, while other enterotoxin preparations not effective on adenylate cyclase system, don't interfere with this model. the a. propose the platelet aggregation as cellular assay to detect enterotoxin fractions effective ...19761028645
[discrimination of ischemic- and glycoside-conditioned st-t segment changes in stress ecg]. 19941029953
humoral reponse to neuraminidase-treated tumor cells.l1210 leukemia cells grew progressively and caused tumor deaths in all recipient mice. however, when these cells had been treated with vibrio cholerae neuraminidase (vcn) prior to injection, tumor deaths did not occur. both untreated and vcn-treated l1210 cells elicited a humoral response, as manifested by an increasing percent of cells in the spleen and peritoneal cavity, with various types of membrane-associated immunoglobulins. progressive tumor growth was associated with a large percent of p ...19761032896
[clinical and therapeutic study of cholera in dahomey. (133 clinical cases)]. 19761036472
[behavior of vibrio cholerae strains of the biotype el tor isolated in apulia in 1973, in relation to various antibiotics and chemotherapeutics].the tests carried out on the strains of vibrio cholerae of the el tor biotype, isolated during the epidemic in apulia in 1973, brought to light the sensitivity of all the strains to various antibiotics and chemotherapeutic substances. only one initially sensitive strain, when it was isolated again in the same patient, proved to be resistant to tetracycline. on the basis of this discovery and others communicated in published works, the authors outline the problems posed by the emergence of antibi ...19751047628
ligand-induced redistribution of lymphocyte membrane ganglioside gm1.dynamic aspects of the binding of cholera toxin to lymphocyte membranes have been studied. we have shown that the receptor for this ligand--the gm1 ganglioside--can be laterally redistributed into aggregates and caps. exogenous purified gm1 inserted into gm1-deficient human leukaemic cells can undergo a similar pattern of ligand-induced mobilisation. these observations may have important implications for both the general behaviour of cell surface glycolipids and the mode of action of cholera tox ...19751057731
interaction of cholera toxin and membrane gm1 ganglioside of small intestine.ganglioside gm1 was isolated from the small intestinal mucosa of man, pig, and beef and amounted to 0.1, 2.0, and 43 nmol per g fresh weight, respectively. these differences in gm1 content were associated with a quantitatively differing ability of the mucosal cells to bind cholera toxin. human cells bound about 15,000 toxin molecules when saturated with the toxin, porcine cells 120,000, and bovine cells 2,600,000 molecules. the association constant (ka) of the cholera toxin binding was, for cell ...19751058471
stimulation of epinephrine-sensitive fat cell adenylate cyclase by cytosol: effect of cholera toxin.cytosol prepared from rat epididymal fat cells by centrifugation at 100,000 x g for 1 hr was found to enhance the basal and epinephrine-sensitive adenylate cyclase [ec 4.6.1.1; atp pyrophosphate-lyase (cyclizing)] of fat cell ghosts. cholera toxin also stimulated adenylate cyclase and increased the response to epinephrine in fat cells. a possible relationship between the adenylate cyclase modifying activities of cytosol and the effects of cholera toxin was sought. cytosol from freshly prepared f ...19751059143
type-specific action of vibriocidal antibody on vibrio cholerae.the vibriocidal activity of inaba and ogawa antisera, from which cross-reacting agglutinin had been absorbed, was specific for vibrio cholerae strains of the homologous serotype. no vibriocidal action against strains of the heterologous type was detected. the sera appeared to be equally effective in killing organisms of different biotypes (classical, intermediate, and eitor), provided that these were of the homologous serotype (inaba or ogawa). however, they had been raised against strains of th ...19751059707
mobility of cholera toxin receptors on rat lymphocyte membranes.fluorescein-labeled cholera toxin binds detectably to 40-60% of rat mesenteric lymph node cells and induces a temperature-dependent redistribution (patch and cap formation) of cell surface toxin receptors. the redistribution is inhibited by several "metabolic," "microtubule," and "microfilament" inhibitors, by concanavalin a, and by anticholera toxin igg. various studies indicate that cholera toxin is at least bivalent, and that this property may be related to both the induction of receptor redi ...19751060063
immunological studies in murine osteosarcoma. immunogenicity, growth kinetics, and immunotherapy.a transplantable murine osteosarcoma is described. following transplantation into a syngeneic mouse the tumor grows rapidly and kills the mouse with pulmonary metastases simulating human osteosarcoma. a cell-mediated antibody response is evoked in the host mouse as demonstrated by in vivo and in vitro tests. the number of pulmonary metastases may be decreased with adjunctive immunotherapy following excision of the primary tumor. immunotherapeutic materials include bcg and isologous cells treated ...19761063129
immunotherapy of human leukemia with neuraminidase-modified cells. 19761063908
[evaluation of diagnostic value of adrenal scintiscanning and venography (author's transl)]. 20051063995
comparative study of alkaline phosphatase activity in lymphocytes, mitogen-induced blasts, lymphoblastoid cell lines, acute myeloid leukemia, and chronic lymphatic leukemia cells.alkaline phosphatase [orthophosphoricmonoester phosphohydrolase (alkaline ph optimum), ec 3.1.3.1] purified from a burkitt lymphoma cell line (daudi) and moloney-virus-induced murine leukemia (yac) showed unique catalytic properties in substrate specificity and inhibition by cysteamine-s-phosphate. it migrated on polyacrylamide gel electrophoresis in a single activity band. alkaline phosphatase with similar properties was found in several human lymphoblastoid cell lines, in chronic lymphatic leu ...19761064015
elucidation of hydrocarbon structure in an enzyme-catalyzed benzo[a]pyrene-poly (g) covalent complex.the carcinogen, benzo[a]pyrene, was covalently attached to poly (g) by liver microsomes from rats pretreated with 3-methylcholanthrene. the complex was hydrolyzed with enzymes or base and products were isolated by sephadex chromatography. absorbance and fluorescence spectra of the products fit that of red-shifted pyrene aromatic system and suggest that metabolism has occurred at the 7-, 8-, 9-, and 10-positions of the hydrocarbon. benzanthracene or chrysene fluorescence were not observed in thes ...19761064016
[personal experiences with congenital cysts and fistulas of the neck]. 20051064065
absorption of iron from slow-release and rapidly-disintegrating tablets - a comparative study in normal subjects, blood donors and subjects with iron deficiency anaemia.the absorption of iron from slow-release and rapidly-disintegrating ferrous sulphate tablets has been compared using a double radioiron isotope technique. the studies were performed in 15 normal subjects, 20 blood donors and 10 patients with iron deficiency anaemia. the preparations containing 100 mg of ferrous iron were given twice daily on alternate days for 10 days. the absorption differed significantly between the three groups of subjects, being highest in the anaemic patients and lowest in ...20051064905
the intravenous infusion of co-trimoxazole in cases of septicaemia: tolerance and results of treatment.the tolerance to co-trimoxazole given by intravenous infusion was investigated in 25 patients suspected to be suffering from septicaemia. one patients developed allergic skin manifestations and two had increased difficulties with cardiac insufficiency, probably on account of the infusion. the other patients tolerated well. the results of treatment of 11 patients with septicaemia were good in 8 cases. in 2 cases, the poor results of the treatment can be explained by the presence of undrained absc ...20051064919
those dangerous roentgens and how to control them: ii radiation hazards and protection as they relate to exposures in dental radiography. 20051064920
guest editorial. 20051064923
scda policy on continuing education. 20051064924
ada standards for dental prepayment programs. 20051064930
dental treatment in the hemophiliac. 20051064933
recurrent dislocation of the mandible. 20051064941
reactive arthritis associated with infection. 20051064948
arthroplasties of the upper extremity. 20051064951
tongue-tie that office gossip. 20051065136
letter: microvilli. 20051065167
achievement award 1976: the robert wood johnson foundation. 20051065210
immune markers in adult acute leukemia.three cases of adult acute leukemia were examined for immunologic markers. incubation of leukemic cells with anti-d (igg)-coated erythrocytes was used for the identification of monocytes; sheep erythrocytes were employed for t-cells and fluorescein-conjugated anti-mixed immunoglobulins for b-cells. it was shown that igg receptors (monocytes) were present on immature cells with predominant monocytic components; t- and b-cell markers were absent in the mono- and myelocytic leukemias.19761065217
the child with leukemia: in a special hematology clinic. 20051065220
a disconnection alarm for the bennett ba-4 ventilator.a simple warning device is described to attach to a bennett ba-4 ventilator. it has proved reliable in practice when the ventilator is operated on pressure limit.20051065222
intra-arterial injection of a barbiturate--a case report. 20051065224
[the detection of a case of scleroderma during pre-prosthetic dental examination]. 20051065241
[adenomatoid odontogenic tumor]. 20051065244
inhibition of calcium phosphate precipitation by human salivary secretions. 19761065265
mandibular growth and dysfunction: a cephalometric and electromyographic analysis of a cross-bite case. 20051065355
[induction of phagocytosis by immunotherapy against leukemic leukocytoblasts].since 1975, the authors have been working in immunochemotherapy in acute myeloblastic leukemic adult patients. autologous leukemic leucocytoblasts have been cultured with vibrio cholerae neuraminidase (nvc). thereafter, neoplastic cells were radiated with cobalt bomb and frozen to--70degreesc and afterwards 5 x 10(6) of these leucoblasts were intradermally injected to each patients every eight days. all patients received between six to ten injections. so far, ten such patients have been followed ...19761066088
immune responses in cholera vaccinated persons. 19761066435
choleragen-mediated release of trapped glucose from liposomes containing ganglioside gm1.125i-labeled choleragen was bound to liposomes containing galactosyl-n-acetylgalactosaminyl-(n-acetylneuraminyl)-galactosylglucosylceramide (gm1), but not in large amounts to ganglioside-free liposomes nor to those containing n-acetylneuraminylgalactosylglucosylceramide (gm3), n-acetylgalactosaminyl-(n-acetylneuraminyl)-galactosylglucosylceramide (gm2), or n-acetylneuraminylgalactosyl-n-acetylgalactosaminyl-(n-acetylneuraminyl)-galactosylglucosylceramide (gd1a). choleragen released trapped gluco ...19761068459
[case of chronic myeloid leukemia complicated by nephrolithiasis]. 20051068596
therapeutic effectiveness of neuraminidase-treated tumor cells as an immunogen in man and experimental animals with leukemia.the immunogenicity of leukemia l1210 in dba/2 ha and 6c3hed lymphosarcoma tumor cells in c3h/f mice was significantly increased after treatment with v. cholerae neuraminidase. dba/2 ha and c3h/f mice repeatedly immunized with neuraminidase-treated tumor cells rejected subsequent challenge of 10(7) or 10(6) untreated tumor cells, respectively. based on the 51cr microcytotoxicity assay, both strains of mice showed strong complement-dependent antibody titers and cell-mediated immunity. sera and spl ...19761069551
adjuvant immuno- and/or chemotherapy with neuraminidase-treated autogenous tumor vaccine and bacillus calmette-guérin for head and neck cancers. 19761069553
equity versus debt financing. 20051070367
location. 20051070368
don't smoke smoke smoke that cigarette. 20051070373
when death necessitates selling a practice. 20051070377
public speaking. how to become a better public speaker. 20051070389
wolf cubs learn that teeth can last a lifetime. 20051070393
once daily dosage beta-blockade: antihypertensive efficacy of slow release oxprenolol as related to renin and age.a single daily dose antihypertensive therapy with a new slow-release (sr) form of the beta-adrenoceptor blocking agent oxprenolol was as effective as a standard tid beta-blocker regimen in maintaining therapeutic effects over 24 hours. the good overall response rate (target larger than or equal to mmhg diastolic) of 67% was achieved in eight of the 11 high renin patients and 16 out of the 20 normal renin ones; the five low renin patients, who were also older, proved to be non-responsive. in term ...20011071402
inter-relationship between autoregulation of glomerular filtration rate, tubuloglomerular feedback and juxtaglomerular renin activity in normotensive and hypertensive rats.1. reduction of renal perfusion pressure from 133 mmhg to 117 mmhg in control rats did not induce a significant change of kidney glomerular filtration rate (gfr) or nephron gfr determined in distal tubules. in contrast, nephron gfr measured in proximal tubular segments (ngfr-p) fell significantly. 2. qualitatively the same response of filtration rate to changes of arterial blood pressure was found in the chronically clipped kidneys of goldblatt hypertensive rats after acute removal of the clip. ...19761071583
[contribution to the study of the ion fluoride determination in the public water supply system (author's transl)]. 20051073693
[the nature of nuclear enlargement in urethane and isoprotenol-stimulated salivary glands (author's transl)]. 19751073694
sialic acids and sialyltransferases in murine lymphoid cells: indicators of t cell maturation. 19751079171
mechanism of action of cholera toxin. specific inhibition of toxin-induced activation of adenylate cyclase. 19751079778
[lymphocytes of perypheral blood in p.r. under treatment with penicillamine d]. 20051081252
six and one-half month old infant with fever and irritability. 19751081274
results of direct coronary artery graft reconstruction. a five-year clinical and arteriographic appraisal.three hundred thirty-six patients with severe coronary artery disease were operated upon between june, 1969, and december, 1974. all were followed from 1 to 66 months (average, 37 months) with respect to survival and late myocardial infarction. the patients operated upon were compared statistically with a group of unoperated patients, and this evaluation demonstrated significantly better late survival in the surgically treated patients who had double- and triple-vessel disease. two hundred thirt ...20051081380
absence of heart-rate effects in isolated frog heart irradiated with pulse modulated microwave energy.isolated frog hearts were irradiated with pulse modulated microwave energy synchronized with the ecg. no statistically significant or otherwise observable differences were found between the heart rate of irradiated groups and the nonirradiated control group. experiments were performed to explore the possible effects of currents induced between the recording electrodes. increases in heart rate occurred when applied current pulses between 20 and 30 ma were synchronized with the ecg during an inter ...20051082513
[grastric mucosa rupture with hematemesis caused by blunt abdominal trauma]. 20051082554
[determination of choleragen activity in tadpoles].a method of titration of the v. cholerae toxin obtained from the broth culture filtrates is presented. in difference from the earlier methods, the larvae of rana temporaria were used as a test object. the tadpoles were placed in the vessels with water containing graded concentrations of the toxin. the titer of the toxin activity was evaluated by the percentage of dead tadpoles. the concentration causing the death of 50 per cent of the tadpoles in the course of the 24 hours was taken as a unit of ...19751082777
ampicillin-resistant hemophilus sp. 19761082793
[massive lower gastrointestinal hemorrhage of diverticular origin. diagnostic and therapeutic problems]. 20051082809
impaired responsiveness to folinic acid protection in methotrexate-resistant l5178y cells. 20051082814
[influence of substances that change the serotonin level of the brain on the analgesic effect of promedol in rats].in tests with determination of pain reaction in rats registered by their squeak and arising in reponse to a single electric irritation of the tail evidence was obtained to the effect that substances both lowering the serotonin content in the brain (p-chlorphenylalanine, reserpine) and raising it (5-oxytryptophan, pargilin) cause a fall of the threshold, viz. 5-oxytryptophan and pargilin display antagonism to the analgetic effect of trimeperidine hydrochloride, whereas p-chlorphenylalanine, and i ...19761082823
co-operation between macrophages and a factor from lymphocytes in tumor lysis in vitro.peritoneal cells from c3h/he mice immunized against syngeneic mm46 ascites tumor cells specifically lysed these tumor cells in vitro, while spleen cells or lymph node cells from immunized hosts were completely ineffective. the effector cells differed from lymphocytes in their morphological characteristics, property of adherence, phagocytic activity, and sensitivity to anti-theta serum. the cytolytic action of the peritoneal cells was not due to cytotoxic lymphocytes, but to macrophages. these ma ...20051082827
upper gastrointestinal endoscopy in the pediatric patient.the value of upper gastrointestinal endoscopy in adults is well established. this study of 50 children demonstrates that upper gastrointestinal endoscopy can be performed safely and effectively in this age group without general anesthesia. endoscopy appears more sensitive than radiology in the detection not only of superficial mucosal lesions, but of gastric and duodenal ulcers as well.20051082828
[bronchial carcinoma (author's transl)]. 20051082836
an avoidable tragedy-uveitis. 20051082837
[intelligence (author's transl)]. 20051082839
emergency arteriography in acute gastrointestinal bleeding.emergency arteriography was carried out on 35 patients with acute gastrointestinal bleeding, in 31 of them within two hours of active bleeding (a haematemisis; a diagnostic change in central venous pressure, pulse rate, or blood pressure; or gastric aspiration of fresh blood). a definite site of bleeding was identified in 27 patients (77%)-this being a small-intestinal vascular abnormality in three--and a probable site in three. confirmation of the bleeding site was obtained in 20 out of 23 pati ...20001083756
epithelial regeneration of transposed intestine after high doses of x-irradiation.the regeneration capacities of normal and transposed small bowel epithelium were compared in rats after applying high doses of x-irradiation. it has been shown that the potency of the mucosa to regenerate is much higher than assumed and that the mucosa can regenerate after single doses varying from 2000-5000 r. even in the villus epithelium and in flat epithelium covering infiltrates of the lamina propria cells survive, which are still able to resume proliferative activity several days after irr ...19761083838
cell-mediated immunity: delayed-type hypersensitivity and cytotoxic responses are mediated by different t-cell subclasses.cell-mediated immunity includes both the generation of cytotoxic cells and initiation of delayed-type hypersensitivity (dth). the resting t-cell population, before stimulation by antigen, already contains cells of the lyl subclass that are programmed to initiate dth (and helper function) but not cytotoxic responses, as well as ly23 cells which can generate killer activity (and suppressive function) but not dth. the central implication of these findings is that the broad division between humoral ...20011083891
address given to n.s.w. college of nursing on avoidable factors in maternal morbidity. 20021083928
[diagnostic and therapy of postoperative cardiac low-output-syndrome by means of intraaortic balloon pumping (iabp) or external counterpulsation (ecp)--a comparison (author's transl)].a beneficial influence on the myocardial energy imbalance of the hypoxaemically damaged heart can be reached with either intraaortic balloon pumping (iabp) or external counterpulsation (ecp). in the realm of our acquired clinical experience with two groups of patients, the technical demands of these cardiac assist devices are discussed and distinguished from one another in relation to different indications.20011084037
surgical treatment of bronchiectasis in kartagener's syndrome.a case of kartagener's syndrome in which bilateral partial pulmonary resection was performed is reported. the literature concerning the surgical treatment of severe bronchiectasis is reviewed.20021084204
[research on v. cholerae anti-antibodies (agglutinating and vibriocidal) in patients affected by cholera-like gastroenteritis. studies performed during the cholera epidemic occurred in apulia in august-september 1973].agglutinating and vibriocidal antibody titers anti-v. cholerae of the serotypes ogawa and inaba, were determined in sera from 189 patients with cholera-like diarrheas during the epidemic of cholera occurred in august-september 1973, in bari. antibodies were determined in 74,2% of 70 patients, whose in the faeces and vomiting were isolated strains identified as v. cholerae, biotype el tor, serotype ogawa. this frequency was higher against the serotype ogawa. the antibodies could be proved very ea ...19751084731
photobiological activity of furazolidone. 19761086295
a streptomycin-sensitive revertant of a streptomycin-dependent strain of vibrio cholerae.a study was made of a streptomycin-sensitive revertant of a streptomycin-dependent strain of v. cholerae. the revertant, designated as strain kb599, appears to be avirulent in animal experimental models. however, no evidence of multiplication was found in infant mice.19761086742
intestinal immunization with soluble bacterial antigens: the example of cholera toxoid.the studies described are aimed at a better understanding of the intestinal immunological system and its role in protection against enteric infection. the cellular kinetics of the intestinal immune response to cholera toxoid were studied in rats and the protection afforded by toxoid immunization was studied in dogs. memory was demonstrated in the gut immune system. plasma cells containing iga antitoxin appeared in large numbers in gut lamina propria when intraduodenal boosting followed either in ...19761086763
membrane expression of thy-1,2 and gm1 ganglioside on differentiating t lymphocytes.c3h mouse bone marrow cells were separated by discontinuous bsa gradient centrifugation. marrow cells from the 17 to 19%, 19 to 21% to 23%, 23 to 25%, 25 to 27% interfaces and the cell pellet were treated with thymic factor (tf) or with vibrio cholerae neuraminidase (vcn), followed by anti-thy-1,2 and anti-gm1 ganglioside antisera. antigens determined by anti-thy-1.2 or anti-gm1 were expressed either with tf or vcn within a 30-min incubation. cells expressing these antigens after vcn or tf treat ...19761086862
surface molecules of cultured human lymphoid cells.cell surface molecules of cultured human lymphoid cells were selectively labeled by lactoperoxidase-catalyzed iodination and examined by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. two major iodinated species with apparent mol. wts. of 27 000 and 35 000 daltons were detected on autoradiographs of the labeled proteins of human lymphoid cell lines believed to be of thymus-independent (b) cell origin. neither molecule was detected on putative thymus-dependent (t) l ...19761087235
intramembranous particle distribution at the node of ranvier and adjacent axolemma in myelinated axons of the frog brain.the plasma membrane of myelinated axons in the frog brain has been examined by the freeze-fracture technique. the cytoplasmic leaflet of the axolemma contains numerous randomly distributed particles in nodal and internodal regions but relatively fewer particles in the axoglial junctional portion of the paranodal region. particle distribution is even less uniform in the outer leaflet of the axolemma, which contains a low concentration of particles in the internodal region and a relatively high co ...20051087339
percutaneous stimulation in the treatment of acute and chronic pain. 20051087340
nucleosides. 1. 9-(3'-alkyl-3'-deoxy-beta-d-ribofuranosyl)adenines as lipophilic analogues of cordycepin. synthesis and preliminary biological studies.a series of lipophilic 9-(3'-alkyl-3'-deoxy-beta-d-ribofuranosyl)adenines of increasing chain length was synthesized from the corresponding branched sugars via titanium chloride catalyzed ribosylation of chloromercuri-6-benzamidopurine. enhanced growth inhibitory activity was observed against (ccrf-cem human lymphoblastic leukemia cells in culture as the length of the alkyl side chain in the sugar and the resultant lipophilic character of the nucleoside were increased. experiments involving inco ...19761087343
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