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evidence for clathrin mobilization during directed phagocytosis of shigella flexneri by hep2 cells.the enteroinvasive species shigella flexneri expresses a plasmid-mediated capacity to penetrate epithelial cells by directed phagocytosis involving actin polymerization. in the present work, hep2 cells were depleted of intracellular k+ in order to arrest receptor-mediated endocytosis and to evaluate the role of this endocytic pathway in the internalization of invasive microorganisms. such a treatment, which efficiently inhibited diphtheria toxin endocytosis and dissociated clathrin coats of the ...19892695740
genotoxicity testing: phage t7 inactivation test of various furan and arenofuran derivatives.the genotoxic activities of 28 furan and arenofuran derivatives were tested by the phage t7-inactivation test. the genotoxic activity of the compounds was characterized quantitatively. all the compounds studied have pronounced genotoxic activities in our system. empirical rules relating structure to genotoxic activity were found. data obtained with our system were compared with the results of other biological systems (salmonella assay, sos chromotest, cho/hgprt, gene amplification) in the case o ...19892695762
characterization and autoprocessing of precursor and mature forms of human immunodeficiency virus type 1 (hiv 1) protease purified from escherichia coli.a recombinant plasmid encompassing the human immunodeficiency virus type 1 (hiv 1) protease coding sequence and flanking regions (ala-13 to gly-185 of the pol open reading frame) has been expressed in two distinct strains of escherichia coli, ar58 and ar68. in the first strain, ar58, the primary translation product, a 25 kilodalton (kda) precursor protein, is short-lived and rapidly processes itself to the 11 kda mature protease in vivo. in the second strain, ar68, the 25 kda species is only par ...19892695927
fulminating encephalopathy associated with shigella flexneri. 19892696551
[strengthening the cooperation between transcarpathian surgeons and surgeons of the eastern-slovak region of czechoslovakia]. 20082696814
[clinico-morphological criteria of diagnosis of dysentery and salmonella infections].clinical symptoms and laboratory findings have been evaluated for 108 patients with intestinal infection associated with apparent colitic syndrome. differential diagnosis between dysentery and salmonellosis was not an easy task even though clinical signs of the diseases appeared different. dysentery ran with tenesmus, sigmoid pain and spasms. symptoms of gastritis, intoxication, dehydration, hepatomegaly predominated in salmonellosis. in obscure cases colonic biopsy can be helpful due to high se ...19892696830
[demands for quality and planning standards for model casting]. 20092697127
italian survey on allogeneic bmt for chronic myeloid leukaemia. 20092697445
transferable trimethoprim resistance of shigellae encountered in vellore (south india).shigella flexneri and sh. shigae which are the two most common shigellae encountered in vellore (south india) were found to exhibit resistance to trimethoprim and trimethoprim-sulphamethoxazole. eighty four per cent of this was high level resistance. transfer studies conducted with these strains indicated that this high level resistance is plasmid mediated.19892697688
protein-losing enteropathy. 19892697925
[the etiological structure of shigellosis in the ussr in recent years].the characterization of etiological structure of shigella infection in the whole of the ussr, in individual union republics and at a number of other administrative territories of the ussr in recent years is presented. s. flexneri has been shown to prevail at the territories with unsatisfactory water supply of the population, and s. sonnei prevails at the territories with good water supply. at the former territories s. dysenteriae and s. boydii retain their etiological importance, while at the la ...19892698030
[the role of delayed hypersensitivity in the development of an experimental dysentery infection and vaccinal process].the results of experiments, indicating the development of cell-mediated delayed hypersensitivity (dh) skin reaction, its dependence on the virulence of shigella flexneri 2a, the dose and the character of the antigen used for testing the reaction, are presented. one of the immunologically active components of s. flexneri virulent strain 2a no. 516 is a biologically active thermolabile factor detected in filtrate and supernatant fluid. these data suggest that the immunosuppressive action of the vi ...19892698032
management of asthma: a consensus statement.in developing these international guidelines there were several unifying themes in the diagnosis and simple management of childhood asthma. for the purposes of the meeting, asthma was operationally defined as 'episodic wheeze and/or cough in a clinical setting where asthma is likely and other rarer conditions have been excluded'. in making a diagnosis of asthma, a full history is a prerequisite. additional tests are only used to support clinical impression and to provide objective evidence for t ...20092698121
growth factors and the regulation of pre- and postnatal growth.peptide growth factors represent a largely paracrine level of intercellular communication that is basic to the process of life. growth factors are present in the ovum and are amongst the first products expressed by the embryonic genome. they function as both signals and progression factors for embryonic tissue growth, induction, differentiation, maturation and function. while a widespread tissue expression is demonstrable during fetal development, and in certain postnatal tissues such as the epi ...20092698147
neonatal hypertension. 20092698384
[some definitions for better understanding of piezography]. 20092698392
microvascular angina and panic disorder.recent cardiac studies have suggested that patients with chest pain and angiographically normal coronaries have "microvascular angina" (mva). in contrast, prior psychiatric studies have shown that some of these patients have panic disorder (pd). we compared the clinical and psychologic characteristics of fifteen patients with mva and fifteen patients with panic disorder (pd), and examined response to lactate infusion in a subgroup of mva patients. although 40 percent of mva patients met criteria ...20092698394
[from cardiac catheterization to the study of left ventricular function. importance of relaxation and diastole in ischemic cardiopathy].some of the most recent developments on left ventricular function derived from brutsaert's work on triple control of contraction and relaxation, and on the new division of the different phases of the cardiac cycle, are reviewed. this allows a re-assessment of the different hemodynamic parameters obtained from cardiac catheterization, which were then applied to relaxation and diastole and to coronary artery disease.20072698709
clinical role of granulocyte-macrophage colony-stimulating factor.the activity of recombinant human granulocyte-macrophage colony-stimulating factor (gm-csf) for increasing leukocyte production and enhancing mature neutrophil function has been clearly demonstrated in phase i clinical trials in patients with a variety of hematologic and malignant diseases. the focus of current studies includes determination of optimal administration schedules and its use in combination with myelosuppressive chemotherapy, radiation therapy or antimicrobial agents. the utility of ...19892698875
[prostaglandins and cyclic nucleotides in the gastrointestinal form of yersiniosis].in spite of the resemblance of the clinical picture of gastrointestinal yersiniosis and acute dysentery, material differences underlie the pathogenesis of these diseases. yersiniosis is marked by the predominance of an increase in the content of pgf2 alpha, whereas acute dysentery by an increase in the content of pge, which may be accounted for by greater intensity of the allergic manifestations in yersiniosis patients as compared with dysentery. shigellosis runs its course in the presence of th ...19892699095
[the importance of immunofluorescence and cytologic indices in the diagnosis and prognosis of the course of dysentery]. 19892699099
effects of endothelin on the cardiovascular system and on smooth muscle preparations in different species.(1) the actions of porcine endothelin (et), an endothelium-derived vasoconstrictor peptide, have been investigated in several in vitro smooth and cardiac muscle preparation as well as on the blood pressure of anaesthetized rats and rabbits. (2) in isolated visceral smooth muscles (guinea pig ileum, rat colon and uterus, rabbit jejunum) et caused a long-lasting contraction which persisted after repeated rinsing. et did not interfere with the spontaneous phasic activity of the rabbit jejunum or wi ...19892699356
production and characterization of monoclonal antibodies with diagnostic potential against shigella flexneri.highly specific monoclonal antibodies (mcabs), 1am3, 2am1 and 2bm2 were produced and characterized against sh. flexneri 1a, 2a and 2b respectively. iam3 is an igg3 (lambda) type antibody reactive against whole bacteria or the lipopolysaccharide (lps) only; 2am1 is an igg1 (kappa) type antibody which reacts with the polysaccharide component of lps; 2bm2 is an igg3 (lambda) type antibody which binds with both the polysaccharide and protein/peptide components of the lps. the results indicate that s ...19892700207
pulsatile flow changes in the anterior cerebral arteries in infants with patent ductus arteriosus: measured with doppler technique.cerebral hemodynamics were measured, using the doppler ultrasound technique (directed toward anterior cerebral artery through the anterior fontanel), in 6 patent ductus arteriosus (pda) patients with large left to right shunt and in 32 neonates before and just following functional closure of ductus arteriosus. pda was confirmed by color echocardiogram and doppler flow study. all 6 sick babies had prominent retrograde flow in the descending aorta during diastole. the value of pulsatility index (p ...20092700277
[radioimmunologic analysis of insulin (iri) in glucose metabolism in uremic patients].glucose intolerance in uremic patients is often reported in literature. this condition is characterized by an unbalance between production and utilization of glucose as for a trouble of the mechanism of gluco-metabolic regulation. insulin radioimmunoassay (iri) is measured to know the amount of hormone incretion and to verify its efficacy in the glucose utilization. the glucagon load and the double glucagon load are tests employed to study iri response and glucose metabolism in uremia. with the ...20092701029
current management of salivary gland tumors. part 2.the authors base their treatment of salivary gland malignancies on the size of the primary and the histopathologic diagnosis. group 1 includes smaller tumors in the t1 and t2 classification with cell types that are associated with slow growth. a parotidectomy is usually sufficient therapy for tumors in this group. group 2 contains t1 and 2 tumors with more aggressive behavior. total parotidectomy is indicated here, with postoperative radiotherapy. t3 tumors and patients with nodal metastasis or ...19892701414
cross cultural experience in jamaica. 20092704251
the inspiring promise of dental implantology. 20092704492
[resonance stimulation of regional ventilation of the lungs by sound vibration in the prevention of acute respiratory insufficiency]. 19892704716
chronic hip pain and limp in a 3-year-old girl. 20082704930
chronic hip pain and limp in a 3-year-old girl. 20082704930
orbital cellulitis with abscess formation caused by sinusitis. 20092705707
abnormalities in the levels of extracellular and tissue amino acids in the brain of the seizure-susceptible rat.basal and high potassium-stimulated release of endogenous amino acids was measured using brain dialysis in the hippocampus of urethane-anesthetized seizure-resistant (sr) and seizure-susceptible (ss) rats. moreover, the tissue level of amino acids was determined in the hippocampus, sensorimotor cortex, cerebellum and corpus striatum. the basal extracellular concentration of amino acids did not differ between sr and ss rats. however, aspartate release was higher, and taurine and phosphoethanolami ...19892707250
leydig cell tumor of the ovary associated with endometrial carcinoma and containing 17 beta-hydroxysteroid dehydrogenase.a case of ovarian leydig cell tumor associated with adenocarcinoma of the endometrium in a 66-year-old woman is described herein, the eighth such case published. clinically, both masculinizing and feminizing symptoms were observed: an increase in facial hair growth, slight baldness, clitoromegaly, and postmenopausal genital bleeding. three biopsies of the endometrium during a 5-month preoperative period showed atypical hyperplasia. surgically resected material contained a leydig cell tumor of th ...20092707954
preliminary notes on vulnerability of the retina to injury from peripheral laser exposure conditions.if laser exposures to the periphery of the retina from low-energy lasers cause a hemorrhage obscuring the optical pathway to the fovea, resulting in loss of visual function, the risks for soldiers on the battlefield may be greater than previously expected. two off-axis experiments were undertaken to obtain an indication of the hazards involved in exposing the peripheral retina to visible laser irradiation. both off-axis exposures caused immediate vitreal hemorrhages in the periphery. after 80 mi ...19892708055
differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells.expression of transforming growth factor alpha (tgf alpha), and transforming growth factor beta (tgf beta) was assessed in isolated primary rat intestinal epithelial cells as well as a rat intestinal crypt cell-derived cell line (iec-6). a gradient in tgf beta was present, with high concentrations of a 2.5-kb transcript found in undifferentiated crypt cells and progressively lower amounts of the tgf beta transcript in increasingly differentiated villus cell populations. in contrast, the concentr ...19892708531
psychosocial aspects of compliance in children and adolescents with asthma.thirty-eight children and adolescents (ages 7-17 years) with chronic asthma were evaluated on three measures of psychosocial and family adjustment. the children's average theophylline level and percentage of noncompliant theophylline levels (theophylline level less than 5 mg/dl) were correlated with behavior problems, perceived self-competence in controlling their conduct, general feelings of self-worth, and family climate (cohesiveness vs. conflict; level of family organization and control). re ...20092708540
effect of a high-fat meal on the bioavailability of a polymer-coated erythromycin particle tablet formulation.the effect of food on the relative bioavailability of an erythromycin particles-in-tablet formulation was studied in 27 healthy volunteers, using a four-way, crossover study design with the following treatments: one or two erythromycin capsules usp (eryc, parke-davis), or one polymer-coated erythromycin particles-in-tablet (pce, abbott) administered fasting or with a high-fat meal. under fasting conditions the erythromycin particles-in-tablet and erythromycin capsule formulations are bioequivale ...20092708552
topographic organization of the central projections of the spiral ganglion in cats.the morphological organization of inputs from restricted sectors of the cat cochlear spiral ganglion into the cochlear nucleus was studied by making focal extracellular injections of horseradish peroxidase (hrp) into the spiral ganglion. injections resulted in golgi-like labeling of a small cluster of spiral ganglion cells and their peripheral and central axons. large injections involved most of the cells within rosenthal's canal in sectors of the spiral ganglion innervating greater than or equa ...19892708585
tyrosine phosphorylation in the postnatal rat brain: a developmental, immunohistochemical study.we have used antibodies against phosphotyrosine to probe 50-microns cerebellar sections from rats of various ages as well as sections of adult brainstem, cerebrum, and olfactory bulb to investigate the developmental appearance of this phosphorylation system as revealed by light microscopy. while the overall intensity of staining in the cerebellum was highest at 7 days, the pattern of staining in the adult is quite disparate from that seen in younger animals. from 10 to 21 days postnatal, stainin ...19892708590
an 18-month survey of infertility treatment by in vitro fertilization, gamete and zygote intrafallopian transfer, and replacement of frozen-thawed embryos.an 18-month survey of infertility treatment by in vitro fertilization (ivf) and related procedures at the centre for reproductive medicine of the vrije universiteit brussel is described. during this period, 1326 treatment cycles were started in patients with long-standing infertility and 1135 oocyte retrievals were performed in 771 different patients. ivf and embryo transfer (et) after laparoscopic (n = 793) or ultrasonically guided (n = 342) ovum pickup, gamete intrafallopian transfer (gift; n ...20092708873
chlorpromazine derivatives: agents that modify signal transduction mechanisms in intestinal secretion. 20092709243
effect of surfactant-associated protein-a (sp-a) on the activity of lipid extract surfactant.the properties of natural bovine surfactant and its lipid extract have been examined with a pulsating bubble surfactometer which assesses the ability of surfactant lipids to adsorb to the air/liquid interface and reduce the surface tension to near 0 dynes/cm during dynamic compression. studies conducted at 1 mg/ml phospholipid revealed that the surface activity (i.e., the ability to produce low surface tensions) of lipid extracts could be enhanced by incubating the sample at 37 degrees c for 120 ...19892713385
response patterns of purified myeloma cells to hematopoietic growth factors.tumor cells were isolated from the bone marrow of seven patients with multiple myeloma and from the peripheral blood of three patients with plasma cell leukemia using ficoll-hypaque (fh) density sedimentation followed by immune rosette depletion of t, myeloid, monocytoid, and natural killer (nk) cells. enrichment to greater than or equal to 93% plasma cells was confirmed with wright's-giemsa staining, with intracytoplasmic immunoglobulin staining, and with staining using monoclonal antibodies (m ...20092713508
effect of estradiol on the phosphorylation of rat liver ribosome proteins.the effect of estradiol on phosphorylation with gamma-32p-atp of ribosome proteins from polyribosome fraction, isolated from female rat liver is found out. rats (180 g) used were: sham-operated, ovariectomized and treated after ovariectomy for 11 days with 20 micrograms 17 beta-estradiol-dipropionate per 100 g body weight. the estradiol deficiency after ovariectomy decreased phosphorylation, but the estrogenization of ovariectomized rats increases it twice. in vitro the hormone (1-2 mumol/l) [co ...19892714224
early plaque colonization on human cementum.we have described the morphology of developing plaque on cementum in an in vivo human model. slabs of cementum obtained from sound teeth, rendered anorganic with 5% sodium hypochlorite, were glued to orthodontic brackets and positioned on the upper canines, premolars and molars in 8 volunteers. the brackets were removed after 2, 4, 8, 24 h and processed for scanning electron microscopy (sem). within 2 h, a thin pellicle covered the cementum surface, with few micro-organisms detectable. at 4 and ...19892715365
acute pseudobulbar palsy due to bilateral focal cortical damage: the opercular syndrome of foix-chavany-marie.two children are described who suddenly developed an encephalitic illness with intractable bilateral facial seizures. the seizures subsided over several days, but the children were left with the signs of pseudobulbar palsy and are unable to speak or swallow effectively. bilateral destructive lesions in the opercular regions evolved on computed tomographic scans. both children were treated with acyclovir relatively early in the illness, and cerebrospinal fluid and serum antibodies support the dia ...20092715610
regression of kaposi's sarcoma and improvement of performance status by a combined interferon beta and zidovudine therapy in aids patients. 20092715648
production of monoclonal antibodies toward bovine interferons-alpha suitable for immunopurification.five murine hybridoma clones, producing monoclonal antibodies (mabs) to bovine interferon-alpha (boifn-alpha) were established. one of these, f12, secreted mabs giving high titers, in elisa tests, neutralizing both boifn-alpha, -alpha c, and boifn-alpha d activities, belonging to the mouse igg1 class, and having a binding affinity constant of 10(8) m-1. f12 mabs were used for immunoaffinity purification of boifn-alpha, and recombinant boifn-alpha c from escherichia coli extracts was purified to ...19892715671
[fibrinogen and pentoxifylline. results of a french cooperative exploratory study of stage ii arteritis].a collaborative exploratory study was undertaken by 139 private angiologists in 427 out-patients with pvd stage ii treated for 90 days with pentoxifylline 1 200 mg per day. in 306 patients (71,6%) the fibrinogen level was decreased by 0,21 g/l in mean (p less than 0.01). this significant decrease is correlated to the global improvement (p less than 0.01) and is within the magnitude of difference that is associated between vascular death and comparative groups in recent epidemiologic studies. in ...20092715734
hydroxychloroquine overdosage. 20092716004
promising drug combination for sickle cell anemia. 20092716139
immunoblotting analysis of the reaction of wildebeest, sheep and cattle sera with the structural antigens of alcelaphine herpesvirus-1 (malignant catarrhal fever virus).malignant catarrhal fever (mcf) is a disease of cattle and some other ruminants caused by alcelaphine herpesvirus-1 (ahv-1), a virus of wildebeest. the disease also occurs in the absence of wildebeest and is then thought to be caused by a viral agent harboured by the sheep. the structural proteins of ahv-1 have been used as antigens for the immunoblotting analysis of sera from wildebeest, sheep and cattle infected by either ahv-1 or the "sheep-associated" form of the disease. wildebeest sera sho ...19892718352
emergency medicine in the third world: two years as director of the kingston, jamaica, public hospital casualty department.a us emergency physician worked for two years as director of a busy emergency department in a large public hospital in kingston, jamaica (west indies). as expected, medical practice in the third world required caring for patients with far less than he was accustomed to in the way of diagnostic and therapeutic resources. however, more than one lesson in clinical medicine was provided by local approaches to local problems. despite resource limitations, innovations and improvements were effected, p ...20092719369
[viral infection and obstructive cholangiography in children].in the last years it has been suggested that idiopathic obstructive cholangiopathy is a pathologic process with evolutive studies: extrahepatic biliary atresia and neonatal hepatitis. the possibility of a viral agent as the inciting factor has been investigated. this report shows four male and one female with confirmed idiopathic obstructive cholangiopathy with different clinical picture. there was evidence of cytomegalovirus infection in two patients, rubella infection in one patient, hepatitis ...19892719422
scientific methodology in curricular reform. 20092719789
us health care: another canadian sends a message home. 20082720532
complications of cardiac catheterization and angiography in patients with valvular heart disease. va cooperative study on valvular heart disease.complications were surveyed prospectively in 2,029 catheterizations performed on 1,483 patients from the 13 centers participating in the va cooperative study on valvular heart disease. complications were reported in 6.9% of 1,559 preoperative procedures of which 2.6% were major and 0.2% fatal. clinical predictors of complications were hypertension and the precatheterization diagnosis of aortic stenosis. nevertheless, patients with aortic stenosis successfully tolerated left ventriculography, whi ...20092720763
a light microscopic and autoradiographic study of non-irradiated and irradiated ocular wounds.focal gamma irradiation was used to limit the intraocular extension of scar tissue which typically occurs after posterior perforating injury to the eye. standard posterior perforating injuries were created in the right eye of forty-eight rabbits, half of which had the site of perforation focally irradiated using a cobalt 60 ophthalmic plaque. non-irradiated wounds healed with profuse formation of highly cellular and vascularised granulation tissue which invaded the vitreous to form contractile v ...19892721224
a light microscopic and autoradiographic study of non-irradiated and irradiated ocular wounds.focal gamma irradiation was used to limit the intraocular extension of scar tissue which typically occurs after posterior perforating injury to the eye. standard posterior perforating injuries were created in the right eye of forty-eight rabbits, half of which had the site of perforation focally irradiated using a cobalt 60 ophthalmic plaque. non-irradiated wounds healed with profuse formation of highly cellular and vascularised granulation tissue which invaded the vitreous to form contractile v ...19892721224
relationship of skin thickness to duration of diabetes, glycemic control, and diabetic complications in male iddm patients.skin thickness is primarily determined by collagen content and is increased in insulin-dependent diabetes mellitus (iddm). we measured skin thickness in 66 iddm patients aged 24-38 yr and investigated whether it correlated with long-term glycemic control and the presence of certain diabetic complications. with univariate analysis, skin thickness was increased and significantly related to duration of diabetes (p less than .001), previous glycemic control (p less than .001), retinopathy (p less th ...20082721339
dna polymerase i (klenow fragment): role of the structure and length of a template in enzyme recognition.the values of kd and gibbs energy (delta g degrees) have been measured for complexes of the template site of dna polymerase i klenow fragment with the homo-oligonucleotides d(pc)n, d(pt)n, and d(pa)n and hetero-oligonucleotides of various structures and lengths. these parameters were evaluated from the protective effect of the oligonucleotide on enzyme inactivation by the affinity reagents d(tp)2c[pt2+ (nh3)2oh](pt)7 and d[(tp2)c(pt2+(nh3)2oh)p]3t of the template site. the present results and pr ...20092721684
the effects of ultrasonically induced hyperthermia on experimental tumors in the rabbit eye.greene's melanomas, implanted in the anterior chamber of 31 eyes of 19 dutch rabbits, were treated with hyperthermia induced by high intensity focused ultrasound (hifu). the percentage necrosis 24 hr after treatment (n) as a function of steady-state intratumor temperature (t) could be described with n(t) = -181.5 + 4.7t (p less than 0.05). the most frequent side effect was a local hemorrhagic keratitis. the acoustic absorption coefficient and thermal conductivity of the tumor tissue were 0.08 cm ...19892722440
how accurate are faculty evaluations of clinical competence?to determine the degree and sources of variability faculty evaluations of residents for the american board of internal medicine (abim) clinical evaluation exercise (cex).20092723833
a comparison of young teenage, older teenage, and adult mothers on determinants of parenting.a nonrandom socioeconomically homogeneous convenience sample of 150 young adolescent mothers, 260 older adolescent mothers, and 242 older mothers was analyzed according to their standing on key determinants of parenting. the results of a discriminant analysis showed that the young teen mothers differed from the older mothers in terms of knowledge of child development, punitive attitudes toward childrearing, and level of depression. accuracy of classification was improved with the discriminant fu ...20082724173
telephone-mediated lightning injury: an australian survey.each year in australia, about 60 people report injuries attributable to lightning surges while using a telephone during nearby thunderstorms. this paper presents information about such incidents and describes a retrospective survey of more than 300 telephone users reporting injuries possibly attributable to lightning. questionnaires yielded 132 usable responses, and the results were analysed to identify the extent and nature of the lightning injuries. these are compared with direct strike injuri ...20092724384
assessment of the conduction of the cardiac impulse by a new epicardiac surface and stimulation technique (sst-ecg) in langendorff perfused mammalian hearts.the assessment of the effects on the conduction of the cardiac impulse and of refractoriness simultaneously from multiple cardiac structures is important to evaluate the mode of action of new compounds, as well as to investigate undesired cardiac side effects. the measurements of intracardiac electrical activities of special structures have required catheter methods or averaging techniques to produce clear deflections of low-level potential wave forms. we have developed an epicardial surface ele ...19892724989
the processing of spatially transformed text.the present study shows that previous attempts to demonstrate explicit memory for orientation of spatially transformed text were inconclusive. in the present experiments, subjects read spatially transformed sentences and were then given a recognition test that permitted the use of only nonsemantic information. the results revealed clear evidence of incidental retention of nonsemantic information on an immediate test, no improvement in performance under intentional learning conditions, reduced bu ...20092725265
diazepam improves recording of lumbar and neck somatosensory evoked potentials.to determine whether the decrease in muscle artifact provided by diazepam is of sufficient clinical value to justify its use, somatosensory evoked potentials recorded in examinations of 73 consecutive patients were compared with those recorded from 33 subsequent patients who were given 10 mg of diazepam orally just before the examination. with diazepam pretreatment there was clear improvement in the quality of lumbar and neck recordings--increased reproducibility and definition and ease of measu ...20092725575
therapy for early breast cancer. 20092725589
animals released. 20092725649
neuropeptide y afferents have synaptic interactions with histaminergic (histidine decarboxylase-immunoreactive) neurons in the rat brain.the synaptic interaction was identified between histaminergic cells and neuropeptide y (npy)-immunoreactive axon terminals in the caudal magnocellular nucleus, by means of the immunoelectron microscopic mirror method. this observation suggests that npy afferents exert monosynaptic influences upon the functioning of the central histaminergic neuronal system.19892725952
the battered nurse executive. 20072725981
[the best ways of the control of inflammatory diseases of the lung].three approaches to optimal control of inflammatory diseases of the lungs are described. the first approach includes improvement of the diagnostic procedure. the second approach is based on development of new complexes of drug therapy and organization of nondrug therapy. the third approach is prophylactic. the main goals of the approaches are formulated.20092726713
human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-aug codons.human basic fibroblast growth factor (bfgf) is an angiogenic polypeptide mitogen present in a wide variety of mesoderm- and neuroectoderm-derived tissues. bfgf cdna and genomic clones predict a 17.8-kda (155-amino acid) gene product based on the presence of a single putative translational initiator atg codon. however, a bfgf protein isolated from human placenta contains two additional amino acids nh2-terminal to the predicted initiator methionine. we report here that the human cell line sk-hep-1 ...19892726761
advanced primary ovarian carcinoma in pregnancy.a case of advanced ovarian carcinoma in pregnancy is described. the entity is usually difficult to diagnose; when it does occur, the objective should be to optimize both fetal and maternal outcome.20092729395
neural crest origin of trabecular meshwork cells and other structures of the anterior chamber. 20092729413
[round table on the current status of vascular surgery]. 20092729653
breast volume measurement of 598 women using biostereometric analysis.a study of the volumes of the right and left breasts of 598 subjects was undertaken using biostereometric analysis. this measurement uses close-range stereophotogrammetry to characterize the shape of the breast, and is noncontact, noninvasive, accurate, and rapid with respect to the subject involvement time. using chi-square tests, volumes and volumetric differences between breast pairs were compared with handedness, perception of breast size by each subject, age, and menstrual status. no signif ...20092729845
large phosphate shifts with treatment for hyperglycemia.although hypophosphatemia is known to commonly accompany therapy for hyperglycemia, it is not generally appreciated that severe life-threatening depletion of phosphate may occur. i followed up two patients who had precipitous drops during intravenous insulin therapy for diabetic ketoacidosis and hyperosmolar nonketotic state. the patient with diabetic ketoacidosis had a phosphate level nadir that equaled the lowest recorded phosphate level in a living human (0.03 mmol/l). because (1) serum phosp ...19892730261
[papillary cystadenocarcinoma of the kidney. apropos of a case and review of the literature]. 20022732502
[a case of coexisting descending thoracic aortic aneurysm and atypical aortic coarctation treated successfully by surgery using the thromboexclusion method].the thromboexclusion method was successfully applied to a 43-year-old male with aortitis syndrome. preoperative aortogram showed a fusiform aneurysm of the descending aorta just below the left subclavian artery and atypical coarctation of the descending aorta distal to this aneurysm. pressure gradient across the stenosis was about 70 mmhg. the technique of flow reversal and thromboexclusion was performed in this patient because of severe calcification in the aortic arch and the entire descending ...20022732543
listeriosis in midwifery. 20082734133
charting a course for advances in physiology education. 20082735460
personality risk factors for cocaine abuse.to evaluate the role of personality in cocaine abuse, 59 adults meeting dsm-iii criteria for cocaine abuse were compared to similar-aged non-cocaine alcohol abusers and community controls on a dsm-iii measure of personality. cocaine abusers were more likely than non-cocaine alcohol abusers to display narcissistic personality traits (odds ratio 6.86, 95% ci = 4.52, 15.60). (am j public health 1989; 79:891-892.20092735482
late brain abscess years after severe cerebrocranial trauma with fronto-orbitobasal fracture.an 8-year-old boy suffered severe craniocerebral trauma with left-sided fronto-orbitobasal fracture. the ct scan showed minor subdural air inclusions. the child recovered well and had no clinical signs of aftereffects. eight years after the accident, symptoms of intracranial pressure developed progressively with nuchal rigidity and elevated temperature. the ct showed an extensive left fronto-orbitobasal abscess. the intraoperative finding was a brain prolapse both into the frontal sinus and into ...20082736550
late brain abscess years after severe cerebrocranial trauma with fronto-orbitobasal fracture.an 8-year-old boy suffered severe craniocerebral trauma with left-sided fronto-orbitobasal fracture. the ct scan showed minor subdural air inclusions. the child recovered well and had no clinical signs of aftereffects. eight years after the accident, symptoms of intracranial pressure developed progressively with nuchal rigidity and elevated temperature. the ct showed an extensive left fronto-orbitobasal abscess. the intraoperative finding was a brain prolapse both into the frontal sinus and into ...20082736550
effect of replacing glucose with lipid on the energy metabolism of newborn infants.1. indirect calorimetry and primed constant infusion of [u-13c]glucose were combined in 28 appropriate-for-gestational age newborn, parenterally fed infants, in order to measure glucose utilization and glucose oxidation and to estimate lipogenesis from glucose. 2. the infants were randomly allocated to either a group receiving glucose as the non-protein energy source or a group having one-quarter of the glucose energy replaced by intravenous fat. the energy intake (370 kj day-1 kg-1) and protein ...20082736877
effect of replacing glucose with lipid on the energy metabolism of newborn infants.1. indirect calorimetry and primed constant infusion of [u-13c]glucose were combined in 28 appropriate-for-gestational age newborn, parenterally fed infants, in order to measure glucose utilization and glucose oxidation and to estimate lipogenesis from glucose. 2. the infants were randomly allocated to either a group receiving glucose as the non-protein energy source or a group having one-quarter of the glucose energy replaced by intravenous fat. the energy intake (370 kj day-1 kg-1) and protein ...20082736877
hypoxic pulmonary vasoconstrictor response with asymmetric oleic acid injury in the dog.the hypoxic pulmonary vasoconstrictive (hpv) response is characterized by two components: intrapulmonary blood flow redistribution and pulmonary artery pressure (pap) augmentation. whether both remain intact after oleic acid lung injury has not been assessed. in an asymmetric model of right lung oleic acid edema, we examined the relative magnitude of each component on the hpv response to right lung inspired hypoxia. before oleic acid administration, right lung hypoxia decreased perfusion to the ...19892736926
[the obstetric risk in adolescent primiparous females].the obstetric risks in primiparae between 12 and 17 years of age have been reviewed in cases treated at our hospital from 1982 to 1987. we looked for intrauterine foetal deaths, premature deliveries (birth weight less than 2500 g), breech presentations, preeclampsia, caesarean sectio rate, forceps rate, and thirdstage complications. the risks found in the group of 476 young primiparae were compared to those amongst the 26,768 overall deliveries during the same period. the incidence of breech pre ...20072737441
the practice of euthanasia in the netherlands. 19892737857
biological properties of streptonigrin derivatives. iii. in vitro and in vivo antiviral and antitumor activities.antitumor antibiotic streptonigrin (stn-cooh) is a potent inhibitor of avian myeloblastosis virus (amv) and human immunodeficiency virus reverse transcriptases. the carboxyl group at 2'-position of stn-cooh was modified to give esters, hydrazide, amides and amino acid derivatives for biological studies. against amv reverse transcriptase, the hydrazide, amides and amino acid derivatives showed inhibitory activity, which compared favorably to that of stn-cooh, with the id50 values ranging 2-8 micr ...19892737955
orally absorbable d-forphenicinol-cephalosporins.the synthesis and biological evaluation of d-forphenicinol-cephalosporins are described. 7-amino-3-(substituted)-3-cephem-4-carboxylic acid esters were coupled with n-tert-butoxy-carbonyl-d-forphenicinol derivatives. most of cephalosporin analogs in this series had good antibacterial activities and were well absorbed from the gastrointestinal tract in mice. among them, 7-(mono-o-methyl-d-forphenicinol)-3-propenyl analog showed the most significant result in biological evaluations.20092737957
memory deficit caused by compressed air equivalent to 36 meters of seawater.twenty-four students from a diving school undertook a hyperbaric chamber dive to a pressure equal to 36 m of seawater. tests of cognitive function and manual dexterity, performed in the chamber during the 35-min bottom time and before, or after, the dive included immediate and delayed free recall of words presented as 7 lists of 15 each, recognition of previously presented words, number identification, and a forceps pickup of ball bearings. delayed free recall and immediate free recall (primacy ...20092737993
fibrinogen nagoya, a replacement of glutamine-329 by arginine in the gamma-chain that impairs the polymerization of fibrin monomer.structural studies on a hereditary abnormal fibrinogen, fibrinogen nagoya (takamatsu, j., ogata, k., kamiya, t., koie, k., takagi, t., & iwanaga, s. (1979) thromb. haemost. 42, 78), were performed to identify the abnormality responsible for the impaired polymerization of fibrin monomer. upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing conditions, fibrinogen nagoya showed the presence of an extra protein band with an apparent molecular weight of 49,500 in addition to ...20092738036
speech breathing in women.thirty healthy women representing three age groups (25, 50, and 75 years) were studied with respect to general respiratory function and speech breathing. certain subdivisions of the lung volume differed with age: vital capacity, expiratory reserve volume, and residual volume. speech breathing also differed with age and was characterized by differences in lung volume excursion, rib cage volume excursion, lung volume initiation, rib cage volume initiation, and lung volume expended per syllable. ag ...20082739388
leucine-zipper motif update. 19892739731
salvage of upper arm access graft in the presence of symptomatic subclavian vein thrombosis. 20092739834
[investigation of various risk factors associated with colorectal cancer by studying cases and controls].a retrospective study was made of cases of colorectal cancer and controls using 571 cases from various hospitals in valencia (spain) and 1,497 controls from the general population with similar sex, age and residence. the relative risks (rr) and levels of statistical significance of various "risk factors" presumably linked to this cancer were calculated. it was associated with: smoking, the quetelet index (which relates weight and height), chronic constipation and, possibly, sedentary life style, ...20092740568
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