Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| chloroplast and nuclear genomes of chlamydomonas reinhardtii share homology with escherichia coli genes for dna replication, repair and transcription. | most of the cpdna genes studied to date are genes encoding elements of the photosynthetic apparatus and translational machinery. much less is known about genes encoding the polypeptides involved in transcription, cpdna replication, recombination and repair. the similarities between bacterial and some cpdna genes were exploited to identify some of these chloroplast genes using bacterial probes. probes derived from the escherichia coli genes dnaa, reca, uvrc, transcriptional factor rho, and rpoc w ... | 1989 | 2663186 |
| congo red-mediated regulation of levels of shigella flexneri 2a membrane proteins. | the ability of shigella spp. to bind congo red from agar medium is generally correlated with their virulence properties. we used a metabolically active culture of shigella flexneri 2a to determine the effect of congo red on its membrane protein profiles. virulent s. flexneri grown in the presence of congo red at 37 degrees c showed increased levels of three proteins with mrs of 43,000, 58,000, and 63,000 (43k, 58k, and 63k proteins) in the sarkosyl-soluble membrane fractions. the observed phenom ... | 1989 | 2663721 |
| plasmid-associated adherence of shigella flexneri in a hela cell model. | the initial interaction of shigella flexneri with hela cells was studied at 4 degrees c, a temperature that inhibits parasite-directed endocytosis. it was found that invasive strains were 10-fold more adherent to hela cells than were isogenic, noninvasive strains which had lost a 140-megadalton plasmid. adherent strains were also more hydrophobic than were nonadherent strains. | 1989 | 2663729 |
| indicator dilution time-activity curves demonstrated by rapid magnetic resonance imaging techniques and paramagnetic contrast agent. | indicator dilution time-activity curves are demonstrated using magnetic resonance imaging (mri) as the detector and a paramagnetic contrast agent as the indicator. manganese chloride was injected into a flow phantom. the nuclear magnetic resonance (mr) intensity was measured downstream. several flow rates were used. the observed mr intensity decreased as the paramagnetic indicator passed through the imaging plane. the qualitative changes of the mr intensity decrease varied in accordance with ind ... | 2008 | 2663765 |
| france: a focus on the new reproduction. | 2009 | 2663772 | |
| [results in microsurgical carotid artery endarterectomy]. | 100 consecutive carotid endarterectomies were performed by a microscopic technique with monitoring of cerebral perfusion by transcranial doppler sonography and eeg. no additional cerebral deficits occurred in this series. perioperative mortality due to medical complications occurred in 2 instances. during the average follow-up period of 15 months, 1 patient suffered a lethal cerebral infarction ipsilateral to the operated carotid artery and 1 patient a contralateral minor stroke. 2 patients died ... | 2009 | 2665064 |
| [long-term results following breast reconstruction]. | a ten-year experience of breast reconstruction (br) at the gustave-roussy institute (paris) provides material for a long-term analysis of carcinologic and cosmetic results. carcinologic results have been studied in a group of 120 breast reconstructions which was matched to a group of 120 mastectomies without br. no statistical difference was observed both for the overall survival and the disease-free survival in both groups. the percentage of local recurrences in the reconstructed breast was inf ... | 2004 | 2666356 |
| use of monoclonal antibodies to type shigella flexneri in bangladesh. | a panel of 10 mouse and rat monoclonal antibodies specific for different type- and group-specific o-antigenic determinants of shigella flexneri lipopolysaccharide was used to serotype 240 isolates of s. flexneri from bangladesh. three immunoglobulin m antibodies were used in a direct slide agglutination test; seven immunoglobulin g antibodies were absorbed to staphylococcus aureus and used in a coagglutination assay. all but 13 of the isolates could be serotyped by using the monclonal antibodies ... | 1989 | 2666435 |
| captopril test in screening hypertensive patients. | 2009 | 2666599 | |
| percutaneous nephrostomy in pyonephrosis. | a series of 76 pyonephrotic kidneys in 73 patients were drained by percutaneous nephrostomy (pn) tube and examined to evaluate the contribution of this technique to the treatment of pyonephrosis. in 71 patients, clinical symptoms disappeared 24-48 h after the procedure. two patients died from sepsis subsequent to anuria and underlying malignancy. once the acute phase had remitted, interventional procedures were carried out in 39 cases, and constituted the definitive therapy in 36. in 32 cases, e ... | 1989 | 2667249 |
| mechanics of the healed meniscus in a canine model. | the mechanical behavior of the intact canine stifle joint was studied, using a surgical model of meniscal injury and repair. thirty-eight animals were divided into five study groups: group s received only a sham arthrotomy (without a meniscal incision), groups p13 and p26 received peripheral medial meniscal incisions, and groups r13 and r26 received radial medial meniscus incisions. all meniscal incisions were repaired anatomically with absorbable suture. groups p13 and r13 were sacrificed at 13 ... | 1989 | 2667375 |
| detection and treatment of gastroesophageal reflux disease. | the diagnosis of gerd requires the thoughtful evaluation of a patient's symptoms and clinical course. in young patients with classical reflux symptoms in the absence of untoward complications such as structure, bleeding or pulmonary aspiration, antireflux treatment can be instituted without the need for diagnostic testing. a large number of patients will demonstrate a good clinical response to medical therapy. the diagnostic challenge arises when symptoms of reflux masquerade as cardiac and pulm ... | 2009 | 2668171 |
| internalization of shigella flexneri into hela cells occurs without an increase in cytosolic ca2+ concentration. | pathogenic shigella flexneri invades epithelial cells through directed phagocytosis. the role of intracellular free calcium ([ca2+]i) as a signal for this process was tested. no variation in the [ca2+]i could be detected by using the fluorescent indicator fura 2 to measure the [ca2+]i in hela cells during the invasion process. in addition, neither clamping nor maximal decreasing or increasing of the [ca2+]i of hela cells had any effect on their susceptibility to invasion. these data demonstrate ... | 1989 | 2668195 |
| purification, crystallization, and preliminary x-ray diffraction studies of the flavoenzyme mercuric ion reductase from bacillus sp. strain rc607. | the flavoenzyme mercuric ion reductase from bacillus sp. strain rc607 was purified by dye-ligand affinity chromatography. the protein was crystallized from solutions of high ionic strength, and one of the two crystal forms obtained has proven suitable for x-ray diffraction studies. preliminary analysis showed that these crystals belong to the tetragonal space group 1422. the unit cell dimensions are a = b = 180.7 a; c = 127.9 a. the diffraction pattern extends to better than 3 a resolution. crys ... | 1989 | 2668287 |
| molecular cloning and characterization of chromosomal virulence region kcpa of shigella flexneri. | in shigella flexneri, in addition to several well-recognized plasmid-borne virulence loci, at least three genetic loci implicated in pathogenesis have been recognized on the chromosome. to understand more about the pathogenesis of bacillary dysentery at a molecular level, the genetically recognized but previously unidentified kcpa region (one of the chromosomal regions near pure) was cloned and sequenced. a single translatable open reading frame encoding a 12310 dalton protein corresponding to t ... | 1989 | 2668687 |
| fungistatic activity of miconazole against candida albicans in relation to ph and concentration of nonprotonated drug. | at less than 10(-5) m, miconazole (mcz) exerts a fungistatic effect on candida albicans, presumably by interfering with ergosterol biosynthesis. the imidazole moiety of mcz is subject to protonation (pka approximately 6.5). based on pka and greater water solubility of protonated (mczh+) versus nonprotonated (mczo) drug, fungistatic action ought to be markedly affected by environmental ph, but apparently it is not. in this report growth phase, ph, and concentrations of mcz and mczo have been stud ... | 1989 | 2668754 |
| [bacillary dysentery--1987]. | 1989 | 2669032 | |
| macrophages: current views on their differentiation, structure, and function. | macrophages are large mononuclear phagocytes that represent the major differentiated elements of the mononuclear phagocytic system. they arise from distinct progenitors in the bone marrow, and their immediate precursors, the monocytes, emigrate from the vascular compartment into many tissues and organs where they develop into mature macrophages. the latter display diverse morphological and functional characteristics, depending on the environmental stimuli that they receive. this phenotypic heter ... | 2009 | 2669295 |
| liver disease associated with exposure to 1,1,1-trichloroethane. | 1,1,1-trichloroethane is a halogenated hydrocarbon solvent commonly used in industry because of its supposed lack of hepatotoxicity. nonetheless, animal studies performed by several independent groups have shown the solvent to induce fat deposition, vacuolar degeneration, and centrilobular necrosis, changes similar to those seen after exposure to carbon tetrachloride, albeit of a much reduced magnitude, in animals exposed to the agent. four patients with fatty liver disease whose work entailed s ... | 1989 | 2669664 |
| oviducal storage of spermatozoa in the turkey: its relevance to artificial insemination technology. | 1. this paper addresses questions concerning the role of oviducal sperm selection and storage in the relative inefficiency of turkey reproduction. 2. before the onset of egg production, the turkey has the biological potential to store spermatozoa in its oviduct for periods up to 5 weeks; after the onset of production fewer spermatozoa are retained by the oviduct. 3. a better understanding of the biological mechanisms which regulate sperm selection and storage in the turkey oviduct is necessary t ... | 1989 | 2670069 |
| asthma and chronic bronchitis in africa. evidence from epidemiologic studies. | 2008 | 2670473 | |
| putative start codon ttg for the regulatory protein virg of the hairy-root-inducing plasmid pria4. | the nucleotide sequence of the virg gene for a transcriptional activator on the agropine-type hairy-root-inducing plasmid pria4 was determined. the sequence contained one possible open reading frame. the gene product with a molecular size of 26.5 kda was identified by an escherichia coli coupled-transcription-translation system using cloned virg plasmids as templates. however, neither an atg nor a gtg start codon which could give rise to such a protein was identified in the nucleotide sequence. ... | 1989 | 2670679 |
| interleukin-1 potentiates granulopoiesis and thrombopoiesis by producing hematopoietic factors in vivo. | in vivo administration of recombinant human interleukin-1 beta (rhu il-1 beta) selectively enhanced the recovery from granulocytopenia and thrombocytopenia caused by whole body irradiation, in a dose dependent manner. since il-1 itself in vitro had no colony-stimulating activity (csa), we studied whether il-1 can produce hematopoietic factors in vivo, which in turn will promote granulopoiesis and thrombopoiesis. serum from il-1 injected mice showed marked granulocyte/macrophage csa (gm-csa), but ... | 1989 | 2671565 |
| adverse effects of amiodarone. pathogenesis, incidence and management. | amiodarone is an extremely effective antiarrhythmic agent for the treatment of both life-threatening ventricular arrhythmias and refractory supraventricular tachyarrhythmias. subjective minor side effects are common with amiodarone but rarely require discontinuation of therapy and are often handled by dose reduction. serious end-organ toxicity, including pulmonary fibrosis and drug-induced hepatitis, have been the most common indications for discontinuing amiodarone therapy in these patients. | 2009 | 2671595 |
| electron microscopy for the rapid detection and identification of viruses from clinical specimens. | the advantages of using electron microscopy for rapid diagnosis of virus infection from clinical specimens, for identification of virus isolates with unusual properties, and for monitoring endogenous agents in cell cultures are illustrated by several actual cases that have occurred over the years. the importance of using morphological characteristics of viruses for initial identification is emphasized. | 2009 | 2672617 |
| malignant hyperthermia. potential crisis in patient care. | 2009 | 2673033 | |
| synthesis of prostacyclin and thromboxane a2 by rat gastric mucosa. comparison of 1,6-dimethyl-4-oxo-1,6,7,8,9,9a-hexahydro-4h-pyrido (1,1-a)-pyrimidine-3-carboxamide and cimetidine. | the production of prostacyclin (pgi2) and thromboxane a2 (txa2) was studied in an indometacin-induced ulcer model in rats. the specific activities of prostacyclin synthetase and thromboxane synthetase as well as the tissue content of these prostaglandins were determined. the anti-ulcer effect of cimetidine and a novel agent, i.e. 1,6-dimethyl-4-oxo-1,6,7,8,9,9a-hexahydro-4h-pyrido(1,1-a)-pyrimidine-3- carboxamide (chinoin-127) was compared in this respect. the indometacin treatment shifted the b ... | 1989 | 2673252 |
| computer-assisted structural analysis of polysaccharides with an extended version of casper using 1h- and 13c-n.m.r. data. | the computer program casper, used in the structural analysis of polysaccharides composed of repeating units, has been extended. the extended version uses either unassigned 1h- or 13c-n.m.r. chemical shifts or the complete unassigned c,h-correlation spectrum, and can predict the structure of linear and branched oligo- and poly-saccharides. the number of possible structures, consistent with sugar and methylation analysis, can be decreased by the use of 1jc,h and 3jh,h values. the database, which c ... | 1989 | 2673508 |
| morphogen gradients and the control of body pattern in insect embryos. | the basic body plan of insects is set up in response to determinants initially localized at the anterior and posterior poles of the egg. early in development, these determinants give rise to a series of morphogen gradients which in turn trigger a cascade of molecular signals determining the body pattern. this signalling process is outlined and recent experiments testing the roles of these gradient systems in determining anterior and posterior pattern are described. the results of these experimen ... | 2009 | 2673685 |
| clinical & bacteriological profiles of shigellosis in calcutta before & after an epidemic (1984-87). | patients below 5 yr of age, hospitalised for shigellosis over a period of four years (1984-87), were studied. during the epidemic of bacillary dysentery (1984) isolation of different shigella spp. as well as shigella dysenteriae type 1 was high. decreased isolation of sh. dysenteriae type 1 and increased isolation of sh. flexneri was observed during post-epidemic years (1985-87). isolation of different shigella spp. was always above 25 per cent from patients with dysentery and greater than 7 per ... | 1989 | 2674001 |
| identification of shigella invasion genes by isolation of temperature-regulated inv::lacz operon fusions. | penetration and multiplication within cells of the human colonic epithelium are hallmarks of shigella spp. pathogenicity. shigella spp. virulence is regulated by growth temperature. strains phenotypically virulent when grown at 37 degrees c are phenotypically avirulent when grown at 30 degrees c. the number of genes involved in shigella spp. pathogenicity and how many virulence genes are temperature regulated are unknown. to facilitate the study of temperature-regulated virulence in shigella spp ... | 1989 | 2674014 |
| studies on interactions of endotoxin with factors of the contact system of plasma. | 1989 | 2675058 | |
| lymphocyte homing. | the phenomenon of "homing" is discussed with respect to patterns of lymphocyte circulation and the molecules on the surface of both endothelium and lymphocytes that mediate this process. in addition, the data are analysed in the context of a model for lymphocyte homing. | 1989 | 2675225 |
| severe acquired aplastic anemia in children: 11-year experience with bone marrow transplantation and immunosuppressive therapy. | we reviewed the management and outcome of severe acquired aplastic anemia in 36 patients younger than 18 years old between march 1977 and june 1987. in most patients, no cause could be found. the best therapeutic results were achieved with allogeneic bone marrow transplantation from histocompatible related donors (14 patients), with a cure rate of 79%. bone marrow transplantation from mismatched related donors was attempted in two patients and failed in both. immunosuppression using antithymocyt ... | 2009 | 2675660 |
| torsion--treatment indications. | rotational problems, when outside the normal range, are referred to as torsional deformity. these deformities are relatively common in infancy and childhood, generally resolve spontaneously with growth, and rarely persist into adult life. there are few situations in which treatment is necessary. (1) rigid metatarsus adductus that does not resolve during the first six months should be corrected by casting. the long leg cast is most effective, as it controls the rotation of the tibia. with the tib ... | 2009 | 2676305 |
| transcription by rna polymerase i stimulates mitotic recombination in saccharomyces cerevisiae. | the recombination-stimulating sequence hot1 is derived from the ribosomal dna array of saccharomyces cerevisiae and corresponds to sequences that promote transcription by rna polymerase i. when inserted at a chromosomal location outside the ribosomal dna array, hot1 stimulates mitotic recombination in the adjacent sequences. to investigate the relationship between transcription and recombination, transcription promoted by hot1 was directly examined. these studies demonstrated that transcription ... | 1989 | 2677675 |
| status of rotator cuff sonography. | 2009 | 2678244 | |
| latvian dentists in the 1990s: a born-again profession? | 2009 | 2679989 | |
| converging and diverging pathways in polypeptide hormone action. | 2008 | 2680229 | |
| increase of alveolar pressure reduces systemic-to-pulmonary bronchial blood flow in humans. | we studied the effect of positive alveolar pressure (pa) on systemic to pulmonary bronchial blood flow, q?? in humans. the q?? was measured during total cardiopulmonary bypass as the volume of blood accumulating in the left heart. this blood was vented by gravity from the left heart via a cannula introduced in the right upper pulmonary vein and advanced to the lowest portion of the left heart. in group a (n = 10) the qbr(s-p) was measured for 25 to 95 min with constant pa (4.0 +/- 0.2 cm h2o, me ... | 2008 | 2680319 |
| optimized insulin delivery: achievements and limitations. | 2007 | 2680670 | |
| the mhc trans-species hypothesis: in the discussion period. | rather than attempting to summarize what i might have said in my presentation at the symposium honoring professor avrion mitchison and thus merely expounding on data that have in the meantime been published elsewhere, here i will answer some of the criticisms that have been meted out at the trans-species hypothesis in the discussion period. i fancy that av will savour this spiced-up birthday present more than he would its conventional version. | 2008 | 2680919 |
| a 101-kilodalton heme-binding protein associated with congo red binding and virulence of shigella flexneri and enteroinvasive escherichia coli strains. | the ability of shigella flexneri to bind congo red or hemin is associated with virulence. a 101-kilodalton (kda) protein responsible for this phenotype (crb+) in s. flexneri was identified by a tetramethylbenzidine staining procedure which detects heme-protein complexes in polyacrylamide gels. labeling of cell-surface polypeptides with 125i revealed that the 101-kda heme-binding protein is expressed on the cell surface. expression of the protein was regulated by growth temperature and was found ... | 1989 | 2680975 |
| anxiety and physical illness in the elderly. | the prevalence of anxiety disorders increases with advancing age. unfortunately, the diagnosis of anxiety in elderly patients is often reached only after everything else has been ruled out. elderly patients with clinical anxiety often present with physical complaints that mask the underlying anxiety disorder. recognition and management of anxiety disorders in the elderly must be prompt to interrupt the cycle of anxiety-depression, physical illness, and other stresses. | 2009 | 2681174 |
| orientation of reaction center complexes from rhodobacter sphaeroides in proteoliposomes and the effect of o-phenanthroline on electrogenesis during primary photochemical reaction. | the orientation of rhodobacter sphaeroides reaction center complexes (rc complexes) in proteoliposomal membranes was investigated by a direct electrometric method. conditions were found that allow monitoring of only that rc complex fraction that is oriented with its donor side to the inner part of the proteoliposome. it is shown that o-phenanthroline, an inhibitor of electron transfer between primary (qa) and secondary (qb) quinone acceptors, can also inhibit the photoinduced qa reduction. the e ... | 1989 | 2681179 |
| herpes simplex infection associated with pemphigus vulgaris. case report and literature review. | a 55-year-old man had an 8-week history of oral ulcers. studies revealed concurrent pemphigus vulgaris and active herpes simplex infection. there have been seven previous case reports of this association, and these are reviewed. | 1989 | 2681299 |
| indicators of spontaneous and stimulated nitroblue tetrazole test of polymorphous-nuclear leucocytes in acute dysentery patients. | 140 healthy individuals and 93 sick with acute dysentery were subjected to an examination by spontaneous and by bacterial preparations stimulated reaction with nitroblue tetrazole (nbt test). indicators in healthy persons were normal in the spontaneous, and increased in the nbt test, stimulated by bacterial preparations. indicators of the spontaneous nbt test in patients with acute dysentery were raised with a maximum in the period of early convalescence. stimulation by a live shigella culture-- ... | 1989 | 2681402 |
| the presence of nicotine on root surfaces of periodontally diseased teeth in smokers. | there is a growing body of scientific evidence to support the concept that the use of tobacco products significantly contributes to the progression of periodontal disease or is detrimental to healing following periodontal therapy. several studies have shown toxic effects of nicotine on peripheral circulation and the immune response. the purpose of the present study was to identify and compare the quantity of nicotine present on root planed and nonroot planed surfaces of teeth from smokers. twent ... | 1989 | 2681674 |
| mechanism of action of gnrh-induced oocyte maturation. | 1989 | 2681744 | |
| parenteral gold therapy for rheumatoid arthritis: a treatment whose time has gone. | 2009 | 2681757 | |
| regulation of plasminogen activators and their inhibitors in rheumatic diseases: new understanding and the potential for new directions. | over the past several years there has been a rapid expansion in our understanding of the fibrinolytic system. this includes knowledge of the components, availability of recombinant reagents and a better understanding of the regulation of fibrinolysis in health and disease. disturbances in the regulation of the balance between fibrin deposition and removal have been implicated in a number of inflammatory diseases including certain rheumatic diseases. this overview summarizes our knowledge of the ... | 2009 | 2681762 |
| 45 years ago--the pioneer health centre, peckham. | 2009 | 2681768 | |
| sonographic and pathological staging of patients with clinically localized prostate cancer. | we evaluated 64 patients with clinically localized prostate cancer (on the basis of rectal examination, serum acid phosphatase, bone scan and pelvic computerized tomography scan) by transrectal sonography before radical prostatectomy. of the 48 patients with histologically proved localized prostate cancer sonography overstaged the disease in 5 (10%) and correctly staged it in 43 (90%). all overstaged cancer patients were scanned after either prostatic biopsy (4) or transurethral prostatectomy (1 ... | 2009 | 2681836 |
| mucoepidermoid carcinoma arising in a lymphoepithelial cyst--report of a case and review of the literature on branchiogenic carcinoma. | a 59-year-old japanese man who had recently noticed a gradual enlargement in a nodule located in the left anterior part of his neck was admitted for surgical treatment. the histopathological features of the resected tumor were consistent with a typical lymphoepithelial cyst, however, the inner surface epithelium of the cyst showed histological transition to mucoepidermoid carcinoma, which was partially invading the cyst wall. despite clinical efforts in a systemic search, no primary lesions whic ... | 1989 | 2681906 |
| [coexistence of abdominal aortic aneurysm and intraabdominal malignancy; two case reports]. | we experienced two cases of abdominal aortic aneurysm which had intra-abdominal malignancy (early gastric cancer). case 1 was a 72 year-old man who was treated by two-stage operation of them. gastrectomy was performed about 7 months prior to the aneurysmectomy. case 2 was a 70 year-old man who was diagnosed both lethal diseases, renal dysfunction, chronic respiratory failure and multiple ventricular arrhythmia. he was treated by one-stage operation and was discharged with no complications. coexi ... | 1989 | 2682201 |
| a comparison of structural features of the walls of coronary arteries from 10 different species. | the intimal thickness of the coronary arteries of humans less than 20 years of age was compared with that 9 other species. it was found that humans were unique amongst the species studied in showing substantial intimal thickening at an early age. the intimal thickening was associated with defects of the internal elastic lamina (iel), which in humans were not repaired, but which in other species were associated with an effective reduplication of the iel. this reformed iel appeared in other specie ... | 1989 | 2682490 |
| thymotaxin, a chemotactic protein, is identical to beta 2-microglobulin. | thymotaxin, an 11-kilodalton protein chemotactic for rat bone marrow hematopoietic precursors, was purified from media conditioned by a rat thymic epithelial cell line. the nh2-terminal sequence of thymotaxin was identical to that of rat beta 2-microglobulin (beta 2m). antibodies to beta 2m removed thymotaxin activity from the fraction containing the 11-kilodalton protein. chemotactic activity was observed with rat plasma beta 2m, human beta 2m, and mouse recombinant beta 2m, further supporting ... | 1989 | 2683083 |
| effects of sound on fetal cerebral glucose utilization. | 2009 | 2683108 | |
| construction and evaluation of a double mutant of shigella flexneri as a candidate for oral vaccination against shigellosis. | based on studies on the genetic and molecular basis of shigella flexneri invasive properties, we have constructed and evaluated a double mutant of s. flexneri serotype 5 for utilization as a live attenuated oral vaccine against shigellosis. the first mutation, icsa, blocks intracellular spread of bacteria as well as cell-to-cell infection. it affects the capacity of the invasive pathogen to form large abscesses in epithelia. the second mutation, iuc, eliminates production of the siderophore aero ... | 1989 | 2683460 |
| current concepts in the treatment of peptic ulcer disease: a case-oriented approach, part 1. | 2009 | 2683706 | |
| complications of acute pancreatitis. | in 1925, sir berkeley moynihan stated that "acute pancreatitis is the most terrible of all the calamities that occur in connection with the abdominal viscera." the case of m.h. clearly reflects the accuracy of that statement. it should be pointed out that through the exceptional, dedicated care provided by all members of the health care team, a young woman whose predicted mortality approached 100 percent was restored to her previous state of good health, and has since delivered a healthy baby gi ... | 2009 | 2684542 |
| interspecies gene transfer in vivo producing an outbreak of multiply resistant shigellosis. | in 1983, a small outbreak of infections caused by a previously unrecognized multiply-drug-resistant shigella flexneri 3a strain occurred on the hopi indian reservation. the index patient, a diabetic woman with recurrent escherichia coli bacteriuria on prophylactic trimethoprim/sulfamethoxazole (tmp/smz) therapy, was hospitalized with concurrent e. coli urinary tract infection and shigellosis. both e. coli isolated from her urine and s. flexneri isolated from her stool were resistant to ampicilli ... | 1989 | 2685126 |
| volvulus of the gallbladder. report of two cases and review of the literature. | torsion or volvulus of the gallbladder is a rare cause of acute cholecystitis. although it has been reported in all age groups, it is most commonly seen in the elderly. with our increasingly aged population, it behooves the clinician to keep this entity in mind when treating the older patient with abdominal pain. we present two cases of torsion of the gallbladder and review the clinical and pathological aspects of this disease. | 2009 | 2685538 |
| [problems in the epidemiology and prevention of intestinal infections]. | 1989 | 2686152 | |
| [modern theoretical and practical conceptions of the epidemiology of shigellosis]. | 1989 | 2686310 | |
| recent advances in gastrointestinal malignancy. | 2008 | 2686527 | |
| recent advances in gastrointestinal malignancy. | 2008 | 2686527 | |
| multicentre experience in the treatment of burns with autologous and allogenic cultured epithelium, fresh or preserved in a frozen state. | this report describes the clinical results obtained from a multicentre experience of the use of autologous and allogenic cultured human epidermal cells in the treatment of partial and full skin thickness burns. a laboratory has been organized to supply cultured epithelium to burns units in different cities. from may 1986 to december 1988, 58 patients with an age range of 1 to 59 years, and with burns covering between 7 and 95 per cent of the body surface area, have been treated. graftable cultur ... | 1989 | 2686683 |
| a novel maturation marker for human sertoli cells. | the maturation of sertoli cells at puberty is critical for the initiation and maintenance of spermatogenesis. little is known about the factors which control sertoli cell maturation. we have examined sertoli cells in testicular specimens from 44 subjects, ranging in age from 6 months to 67 years, for reactivity with a mouse monoclonal antibody (m2a) using the immunoperoxidase reaction. we found positive reactivity with prepubertal but not postpubertal sertoli cells, suggesting that the antigen d ... | 1989 | 2687179 |
| ioversol clinical safety summary. | the authors evaluated double-blind comparative and open-label clinical trials in 1,186 patients who received ioversol to evaluate the safety and efficacy of ioversol, a new nonionic low-osmolality contrast medium, at iodine concentrations of 32%, 24%, and 16%. the results indicate that ioversol was well tolerated in all patients and showed fewer adverse effects than conventional ionic agents. the diagnostic efficacy of ioversol was comparable to both conventional and other nonionic agents with r ... | 2009 | 2687200 |
| grand multiparity--a nationwide survey. | grand multiparity has been considered to be an obstetric hazard to both the mother and the fetus. in order to evaluate this statement we analyzed the information of a nationwide survey. the delivery records of all women (22,814) attending 30 obstetric wards in israel between november 1983 and january 1984 were analyzed and the medical and obstetric complications associated with grand multiparity were investigated. diabetes, hypertension, malpresentations, multiple births, large-for-gestational-a ... | 2009 | 2687205 |
| use of shigella flexneri ipac and ipah gene sequences for the general identification of shigella spp. and enteroinvasive escherichia coli. | the products of the ipab, ipac, and ipad genes are involved in the expression of the invasive phenotype in all species of shigella and enteroinvasive escherichia coli (eiec). dna probes derived from these genes are accurate indicators of the invasive phenotype (m. venkatesan, j. m. buysse, e. v. vandendries, and d. j. kopecko, j. clin. microbiol. 26:261-266, 1988); however, spontaneous loss of the invasion plasmid or selective deletion of invasion-associated genes may restrict the usefulness of ... | 1989 | 2687318 |
| isoenzyme analysis of typhoid-shigella and escherichia-shigella hybrid vaccines and their parental strains. | isoenzyme analysis can be used to measure phenotypic changes and to characterize bacterial strains. the use of isoenzyme analysis to characterize bacterial hybrid vaccine strains that were prepared for human vaccination is described in this report. the hybrid vaccine strains were two lots of salmonella typhi-shigella sonnei vaccine, two lots of escherichia coli-shigella flexneri vaccine, and their parental strains. the two lots of s. typhi-s. sonnei hybrid vaccine had only 5 of 11 reactive isoen ... | 1989 | 2687324 |
| complement component c1q enhances invasion of human mononuclear phagocytes and fibroblasts by trypanosoma cruzi trypomastigotes. | internalization and infectivity of trypanosoma cruzi trypomastigotes by macrophages is enhanced by prior treatment of parasites with normal human serum. heating serum or removing c1q from serum abrogates the enhancement, but augmentation of attachment and infectivity is restored by addition of purified c1q to either serum source. although both noninfective epimastigotes (epi) and vertebrate-stage tissue culture trypomastigotes (tct) bind c1q in saturable fashion at 4 degrees c, internalization b ... | 1989 | 2687332 |
| adolescents and alcohol--a review of the recent british research. | there is evidence of increased alcohol consumption by young people. this review concentrates on the british epidemiological and psychological studies of adolescent drinking behaviour, with special reference to the cultural and developmental aspects. it is clear that drinking alcohol may be considered a normal part of adolescence and many young people are introduced to it by their parents. however, one area of concern is the amount of drunkenness reported. the way forward is to gain new insights ... | 2009 | 2687340 |
| spontaneous motor activity in healthy volunteers after single doses of haloperidol. | video recordings of the spontaneous motor activity of 6 healthy volunteers after treatment with 0.75 mg haloperidol i.v., or placebo, were transcribed into a time-series protocol of motor behaviour. characteristic changes seen after the injection of haloperidol consisted in a reduction of the motility of the extremities and prolongation of the phases of both movement and immobility of the head. the tested dose of haloperidol induced a distinct rise in serum prolactin and sedation, but had no eff ... | 2009 | 2687356 |
| effects of dihydroergotamine on psychomotor function, neuroendocrine parameters and blood pressure, in healthy volunteers. | following the infusion of 15 micrograms/kg of dihydroergotamine (dhe) a 50-fold rise in growth hormone plasma levels was observed in 9 healthy volunteers. prolactin (prl) secretion was depressed 240 minutes post infusion. for 170 min, diastolic blood pressure was increased reaching a peak of +19 mmhg at the end of the infusion. mild sedation and nausea were induced by the treatment for a total duration of 60 min. | 2009 | 2687357 |
| the induction of interferon production in fibroblasts by invasive bacteria: a comparison of salmonella and shigella species. | as the role of interferon (ifn) in host defense against facultative intracellular bacterial infections continues to expand, it has become increasingly important to understand what cell types can produce ifn following infection and/or interaction with these invasive bacteria. we have demonstrated previously that shigella flexneri was able to induce high levels of ifn in primary cultures of human and murine fibroblasts following bacterial invasion. in this study, we examined the ability of salmone ... | 1989 | 2687612 |
| monoclonal antibodies against the surface antigens of shigella flexneri serotype 1b and shigella dysenteriae serotype 1. | monoclonal antibodies against the surface antigens of shigella flexneri 1b and s. dysenteriae 1 were prepared. the specificities of the antibodies were evaluated by enzyme-linked immunosorbent assay (elisa), and quantitative agglutination using microtiter plate. monoclonal antibodies against s. flexneri 1b, designated sf2b2 and sf2g4, belonged to igg2a and igg1 subclass, respectively. the former was specific for s. flexneri 1b, whereas the latter was reactive not only to s. flexneri 1b, but also ... | 1989 | 2687648 |
| who are borderline patients? | "borderline" is a term used with increasing frequency to describe certain difficult patients. it refers to a heterogeneous population of patients who tend to get involved in impaired doctor-patient relationships. different areas of psychiatry have their own, often conflicting definitions of these disorders. early trauma, neglect and genetic diatheses to axis i disorders commonly occur in the backgrounds of these patients. most have a combination of factors. with the multiple different definition ... | 2009 | 2688086 |
| ct of the wrist for the evaluation of traumatic injuries. | computed tomography (ct) of the wrist can help evaluate many types of posttraumatic injuries, particularly bony trauma. most wrist fractures can be diagnosed with routine radiography, but problematic cases and complicated healing fractures can be difficult to evaluate with conventional radiography. ct provides improved contrast resolution and multiplanar imaging. the results of complex healing fractures and fusion procedures can be facilitated with ct. even in the face of advanced osteoporosis c ... | 2008 | 2688677 |
| ct of the wrist for the evaluation of traumatic injuries. | computed tomography (ct) of the wrist can help evaluate many types of posttraumatic injuries, particularly bony trauma. most wrist fractures can be diagnosed with routine radiography, but problematic cases and complicated healing fractures can be difficult to evaluate with conventional radiography. ct provides improved contrast resolution and multiplanar imaging. the results of complex healing fractures and fusion procedures can be facilitated with ct. even in the face of advanced osteoporosis c ... | 2008 | 2688677 |
| toxic megacolon and perforation caused by shigella. | 1989 | 2688808 | |
| shigella colitis with radiological and endoscopic correlation: case report. | we report a patient with acute colitis secondary to shigella flexneri infection. radiologic and endoscopic studies were obtained during and after the patient's clinical recovery. hypotonic air contrast barium enemas were helpful in evaluating the severity and extent of the disease proximal to the segment viewed by flexible sigmoidoscopy. they showed pseudopolyposis, which has not been previously reported in the acute phase, and other mucosal abnormalities which persisted long after clinical reco ... | 1989 | 2688842 |
| lumen-side topography of the alpha-subunit of the chloroplast cytochrome b-559. | removal of the extrinsic 33 kda polypeptide increased the accessibility to trypsin of a cooh-terminal tridecapeptide epitope of the alpha subunit of cytochrome b-559 (psbe gene product). the sensitivity of the cytochrome epitope to trypsin was not measurably affected by removal of the 16 and 23 kda extrinsic polypeptides, nor increased by removal of the oec manganese along with the 33 kda protein. while protecting alpha-cytochrome b-559 against trypsin, the 33 kda protein is also proteolyzed, su ... | 2009 | 2689226 |
| nutritional anestrus in beef cows: concentrations of glucose and nonesterified fatty acids in plasma and insulin in serum. | twenty-two nonlactating hereford cows exhibiting normal estrous cycles were fed either maintenance (m) or restricted (r) diets until most of the r cows became anestrus; r cows then were fed 160% of the m diet until estrous cycles resumed. concentrations of progesterone, glucose, insulin and nonesterified fatty acids (nefa) were determined in weekly blood samples. blood also was collected frequently, before and after i.v. infusion of 300 ml of a 40% glucose solution, to evaluate responses in bloo ... | 1989 | 2689418 |
| [cataract surgery 220 years ago]. | the author reports on the first 14 cataract extractions performed by karl kaspar von siebold, a würzburg surgeon, in 1766/67. he used daviel's method. at that time there was no anesthesia, no sterility or even antisepsis, and no optical correction of aphakia for his patients. four eyes were lost due to infection and another four had much poorer vision after surgery due to irregular corneal scarring. in six cases both patient and physician were satisfied with the result. siebold's case reports ex ... | 2009 | 2689768 |
| biofilm model experiments in vitro with escherichia coli and shigella strains. | escherichia coli and shigella were cultured together in a glucose-free minimal medium completed only by hog gastric mucin. in mixed cultures inoculated simultaneously one member of the pair more or less overgrew the other. this organism remained predominant when superinfected with its strain pair after 1, 3, 5 or 7 days incubation. other signs of the quasi biofilm character of such cultures are the higher level of free polysaccharides and enhanced viscosity in the medium and higher streptomycin ... | 1989 | 2690554 |
| [field trials with an oral cell-free vaccine made from shigella flexneri]. | the data on the study of the reactogenicity, safety and prophylactic potency of a new acellular vaccine prepared from s. flexneri 2a antigenic complexes are presented. according to the results of two epidemic experiments, the vaccine, introduced by oral administration, showed low reactogenicity, safety and sufficient prophylactic potency. the vaccine decreased morbidity rate in dysentery caused by s. flexneri 2a and ensured the protection of 74% (72-80%) of the vaccinees. the complete course of ... | 1989 | 2692352 |
| platelet-activating factor increases platelet-dependent glycoconjugate secretion from tracheal submucosal gland. | using isolated glands from feline trachea, we examined the effect of platelet-activating factor (paf) on radiolabeled glycoconjugate release and glandular contraction by measuring induced tension in the absence or presence of platelets. paf alone did not produce any significant glandular contraction nor any significant change in glycoconjugate release from isolated glands. in the presence of purified platelets containing no plasma, paf (10(-8) to 10(-5) m) produced significant glycoconjugate sec ... | 1989 | 2692465 |
| falciparum malaria--present day problems. an experience with 425 cases. | clinical details and present day problems encountered in 425 cases of falciparum malaria (pf) are reported. 10.11% had taken chloroquine prior to reporting to us. parasitic count done in 23.05% cases lacked correlation with severity of disease. pattern of fever varied markedly but 5.4% were afebrile throughout and presented only with bodyache and malaise. apyrexial spell was noted in 5.64%. 28.70% had typical facial looks of anaemia and sallow complexion. cerebral symptoms were noted in 3.05%. o ... | 1989 | 2693436 |
| the genetics of protein targeting in escherichia coli k12. | genetic analysis of protein targeting in escherichia coli has been facilitated by the use of lacz gene fusions. strains which contain a fusion between a gene specifying a noncytoplasmic protein and lacz exhibit novel phenotypes that can be exploited to obtain export-defective mutations. analysis of these mutations has demonstrated the importance of the signal sequence and provided some insight into the functions performed by this complex intragenic export signal. in addition, genes that specify ... | 1989 | 2693457 |
| [clinical trial of t-3262 (tosufloxacin tosilate) on salmonella enteritis, and fecal drug concentration and change in the fecal microflora in the acute diarrheal patients. japan research committee of t-3262, research group for acute infectious enteritis]. | for the purpose of evaluation of clinical efficacy, safety and usefulness on salmonella enteritis, t-3262 (tosufloxacin tosilate), a newly developed pyridone-carboxylic acid derivative, was administered to a total of 103 patients and carriers. in addition, in vitro antibacterial activity of t-3262 was determined against the clinical isolates, and compared with those of nalidixic acid (na), pipemidic acid (ppa), enoxacin (enx), norfloxacin (nflx) and ofloxacin (oflx). and when t-3262 was administ ... | 1989 | 2693543 |
| failla memorial lecture. the search for critical cellular targets damaged by heat. | 2009 | 2694212 | |
| [the role of the antilysozyme activity of shigella flexneri as a factor controlling the degree of its resistance to the lytic action of bacteriophages]. | the level of the antilysozyme activity of s. flexneri in ensuring the high level of their phage resistance has been studied. the realization of the phage protective effect of antilysozyme activity has been noted to occur due to disturbances in the lysis of infected bacteria by phage-synthetized lysozyme-like enzyme. the direct relationship between the level of the lysozyme production of bacteriophages and their capacity for overcoming the antilysozyme protection of the host bacterium has been sh ... | 1989 | 2694689 |
| [interleukin-1-inducing activity of the polysaccharide-containing antigens of the cell wall in yersinia pestis]. | the induction of the synthesis of interleukin-1 (il-1) in human monocytes under the influence of the endotoxic preparations (lps) and y. pestis basis somatic antigen has been experimentally studied. the results obtained in this study make it possible to come to the conclusion that the capacity of the endotoxin of y. pestis cell wall, consisting of lps of type r, for inducing the synthesis of il-1 in human monocytes is not different from the corresponding capacity of salmonella and shigella lps, ... | 1989 | 2694696 |
| [autonomic-vascular paroxysms (attacks of panic). (review of the literature)]. | 2009 | 2694700 | |
| [resistance of shigella to antibiotics]. | antibiotic sensitivity of 104 shigella clinical strains and 104 escherichia coli strains isolated from patients with acute dysentery not treated with antibiotics in 1986-1987 was studied. it was shown that 100 per cent of the dysentery pathogens and colon bacilli were antibiotic resistant. strains resistant simultaneously to chloramphenicol, ampicillin, streptomycin, tetracycline, monomycin and kanamycin were the most frequent among the dysentery pathogens. colon bacilli and dysentery pathogens ... | 1989 | 2694990 |
| extra-intestinal manifestations of shigellosis. | 1989 | 2695518 | |
| [molecular pathogenesis of bacillary dysentery caused by shigella flexneri]. | 1989 | 2695659 |