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increased erythrocyte adenosine deaminase activity in children with perinatal human immunodeficiency virus infection.erythrocyte adenosine deaminase (ada) activity was assessed in 33 children born to human immuno-deficiency virus (hiv)-positive mothers. the enzyme values were significantly increased in infected, symptom-free children compared with a control group of hiv-negative subjects (mean +/- sd: 0.34 +/- 0.01 unit/ml red blood cells (rbc) vs. 0.25 +/- 0.04 unit/ml rbc, p less than 0.01) and a further significant increase was found in symptomatic children (0.45 +/- 0.02 unit/ml rbc, p less than 0.01 vs. i ...19892626286
endobronchial rupture from endotracheal reintubation with an endotracheal tube guide.endotracheal tube guides are often used to facilitate endotracheal tube exchange in patients whose airways are difficult to intubate. the absence of reported complications with this technique suggests it is a safe technique; however, we report a case of endobronchial rupture associated with such a guide. diagnosis and management of tracheobronchial tears and alternative approaches to difficult reintubation are described.20062627389
[urinary magnesium levels in precancerous conditions and various stages of squamous cell carcinoma of the larynx].in 100 cases with different stages of planoepithelial laryngeal cancer and in 13 precancerous changes the urine magnesium levels were examined two times by means of absorptive spectrometry before surgery and half a year after. in precancerous period group (i stage according to who) no differences were found in comparison to the control group. as the disease progressed the urine magnesium level deteriorated according to the cancer stages. in iv stage the level was the lowest (p less than 0.01). t ...20082628850
[urinary magnesium levels in precancerous conditions and various stages of squamous cell carcinoma of the larynx].in 100 cases with different stages of planoepithelial laryngeal cancer and in 13 precancerous changes the urine magnesium levels were examined two times by means of absorptive spectrometry before surgery and half a year after. in precancerous period group (i stage according to who) no differences were found in comparison to the control group. as the disease progressed the urine magnesium level deteriorated according to the cancer stages. in iv stage the level was the lowest (p less than 0.01). t ...20082628850
[effect of treatment with recombinant interferon alfa on natural killer activity in patients with chronic type b lymphatic leukemia].the role played by alpha interferon (alpha-ifn) in the treatment of b-type chronic lymphocytic leukaemia (b-cll) has been studied by different authors. despite the inconclusiveness of the results, alpha-ifn seems to be more effective in those patients with low tumour burden (early stages) who have been previously untreated. although the mechanism of action of alpha-ifn is not wholly understood, it is known that this agent is a strong stimulant of the natural killer lymphocytes (nk). nk activity ...20092629126
[statistical and medico-legal investigations on traumatic intracranial injuries (except traffic accidents) on which judicial autopsies conducted].judicial autopsies conducted during the period of 24 years and 3 months (jan 1963-mar 1987) at department of legal medicine, kurume university school of medicine have been recorded a total of 1,157 cases including 256 cases caused by the traumatic intracranial injury death. in this report statistical investigations conducted on 112 cases caused by traumatic intracranial injury death with exception of 144 cases caused by traffic accidental death, and the outline of several cases on those are stat ...20082629481
study on changes in basal lamina width of mucosal epithelium and of capillary in the lamina propria of murine stomach in advance of age.correlation between advance of age and changes of basal lamina width of mucosal epithelium and capillary was estimated in both the fundic gland and the pyloric gland, respectively, by electron-microscopic morphometry, using c57bl/6n mice. in basal lamina width of mucosal epithelium, no change was found in both the glands throughout life. in basal lamina width of mucosal capillary, change related to aging was not found in the fundic gland, but in the pyloric gland; it increased in the old mice. t ...20082630383
study on changes in basal lamina width of mucosal epithelium and of capillary in the lamina propria of murine stomach in advance of age.correlation between advance of age and changes of basal lamina width of mucosal epithelium and capillary was estimated in both the fundic gland and the pyloric gland, respectively, by electron-microscopic morphometry, using c57bl/6n mice. in basal lamina width of mucosal epithelium, no change was found in both the glands throughout life. in basal lamina width of mucosal capillary, change related to aging was not found in the fundic gland, but in the pyloric gland; it increased in the old mice. t ...20082630383
assessment of curette sharpness.nothing to date has appeared in the literature addressing the relationship of specific bevel dimension and clinical sharpness of curette blades. this study investigated the degree of clinical sharpness of gracey curettes following four periods of simulated root planning and, using the scanning electron microscope (sem), determined the approximate number of strokes at which loss of clinical sharpness became apparent. seventy-five new stainless steel curette blades were standardized and randomly a ...20082630619
assessment of curette sharpness.nothing to date has appeared in the literature addressing the relationship of specific bevel dimension and clinical sharpness of curette blades. this study investigated the degree of clinical sharpness of gracey curettes following four periods of simulated root planning and, using the scanning electron microscope (sem), determined the approximate number of strokes at which loss of clinical sharpness became apparent. seventy-five new stainless steel curette blades were standardized and randomly a ...20082630619
assessment of clinical application of test-dose concept for theophylline in patients with respiratory failure.the possibility of clinical application of test-dose concept for theophylline was assessed in 11 patients with serious underlying disease who required theophylline. based on the pharmacokinetic parameters calculated from the single intravenous aminophylline administration, they received a continuous infusion of aminophylline in order to maintain about 10 micrograms/ml plasma which is considered to be the lowest therapeutic level. plasma levels during a constant rate infusion were assayed at 6:00 ...20082630628
assessment of clinical application of test-dose concept for theophylline in patients with respiratory failure.the possibility of clinical application of test-dose concept for theophylline was assessed in 11 patients with serious underlying disease who required theophylline. based on the pharmacokinetic parameters calculated from the single intravenous aminophylline administration, they received a continuous infusion of aminophylline in order to maintain about 10 micrograms/ml plasma which is considered to be the lowest therapeutic level. plasma levels during a constant rate infusion were assayed at 6:00 ...20082630628
[instruction in self care by patients with chronic respiratory failure]. 20072630706
[reiter's syndrome or lyme disease?]. 20082632003
[reiter's syndrome or lyme disease?]. 20082632003
[effects of smoking on human health].in this study, 30 cases of male smokers aged 35.7 +/- 5.2 years mean and 30 male nonsmokers aged 36.6 +/- 6.8 years were selected from a factory. before the assay, everyone smoked one pack of cigarette in a day, after that these tests were done. the experimental results as follows. 1. comparing with control group, the levels of igg and igm in serum of smoking group are lower. it was shown that smoking has an inhibitive effect on phagocytosis and bactericidal of am, so smoking has a damaging and ...19892632033
[effects of smoking on human health].in this study, 30 cases of male smokers aged 35.7 +/- 5.2 years mean and 30 male nonsmokers aged 36.6 +/- 6.8 years were selected from a factory. before the assay, everyone smoked one pack of cigarette in a day, after that these tests were done. the experimental results as follows. 1. comparing with control group, the levels of igg and igm in serum of smoking group are lower. it was shown that smoking has an inhibitive effect on phagocytosis and bactericidal of am, so smoking has a damaging and ...19892632033
[an extensive pedigree of autosomal dominant inheritance of bronchial asthma].this paper reports a particularly extensive pedigree in which 33 (13 men and 20 women) of its 118 members (60 men and 58 women) through four generations had bronchial asthma. there were 22 cases of extrinsic asthma (accounting for 66.7%) which occurred chiefly in the juveniles and 11 cases of mixed asthma (accounting for 33.3%) which occurred mainly in the middle-aged and old people. pedigree chart suggested the pattern of autosomal dominant inheritance. it was also found that when either husban ...20082632035
[an extensive pedigree of autosomal dominant inheritance of bronchial asthma].this paper reports a particularly extensive pedigree in which 33 (13 men and 20 women) of its 118 members (60 men and 58 women) through four generations had bronchial asthma. there were 22 cases of extrinsic asthma (accounting for 66.7%) which occurred chiefly in the juveniles and 11 cases of mixed asthma (accounting for 33.3%) which occurred mainly in the middle-aged and old people. pedigree chart suggested the pattern of autosomal dominant inheritance. it was also found that when either husban ...20082632035
superoxide dismutase activity in some strains of lactobacilli: induction by manganese.dialyzed cell-free extract of lactobacilli was found to contain superoxide dismutase activity by using a test system in which superoxide ion is generated by xanthine oxidase. the specific activities of lactobacillus acidophilus atcc 4356, lactobacillus murinus atcc 35020, lactobacillus acidophilus crl 358, lactobacillus plantarum atcc 8014, lactobacillus casei crl 431, lactobacillus plantarum crl 353, lactobacillus fermentum atcc 9338, lactobacillus buchneri ncdo 110, and lactobacillus fermentum ...19892632048
superoxide dismutase activity in some strains of lactobacilli: induction by manganese.dialyzed cell-free extract of lactobacilli was found to contain superoxide dismutase activity by using a test system in which superoxide ion is generated by xanthine oxidase. the specific activities of lactobacillus acidophilus atcc 4356, lactobacillus murinus atcc 35020, lactobacillus acidophilus crl 358, lactobacillus plantarum atcc 8014, lactobacillus casei crl 431, lactobacillus plantarum crl 353, lactobacillus fermentum atcc 9338, lactobacillus buchneri ncdo 110, and lactobacillus fermentum ...19892632048
ozagrel hydrochloride monohydrate, a thromboxane synthase inhibitor, and its metabolites as inhibitors of hepatic microsomal drug metabolism.the change in the hepatic oxidative drug-metabolizing capacity in humans treated with ozagrel hydrochloride monohydrate (oza), an imidazole derivative and a new thromboxane a2 synthase inhibitor, was studied and the inhibitory potencies of the metabolites of oza (m-1 and m-2) on the mouse hepatic microsomal monooxygenase system in vitro were compared with that of oza. in vitro, m-1 and m-2, which are the beta-oxidized form and the reduced form of oza, respectively, inhibited aminopyrine n-demeth ...19892632083
ozagrel hydrochloride monohydrate, a thromboxane synthase inhibitor, and its metabolites as inhibitors of hepatic microsomal drug metabolism.the change in the hepatic oxidative drug-metabolizing capacity in humans treated with ozagrel hydrochloride monohydrate (oza), an imidazole derivative and a new thromboxane a2 synthase inhibitor, was studied and the inhibitory potencies of the metabolites of oza (m-1 and m-2) on the mouse hepatic microsomal monooxygenase system in vitro were compared with that of oza. in vitro, m-1 and m-2, which are the beta-oxidized form and the reduced form of oza, respectively, inhibited aminopyrine n-demeth ...19892632083
[welfare and medical care in an aging society. 35. problems in geriatric nursing]. 20082632857
[myopathy in the uremic patient: apropos of a case].uremic myopathy is relatively unknown, despite the fact that it can be quite a severe handicap. it is a non-specific proximal myopathy which must be distinguished from uremic polyneuropathy. several disorders linked to renal insufficiency have been implicated, but these only play an adjuvant role with regard to renal osteodystrophy. indeed the presence of myopathy in cases of severe osteodystrophy, its similarity to the myopathies associated with different types of osteomalacia and hyperparathyr ...20082633067
long residual activity of bacillus sphaericus 1593 against culex quinquefasciatus larvae in artificial pools.the microbial larvicide, bacillus sphaericus 1593, was evaluated against culex quinquefasciatus larvae in artificial pools at huay kwang area in bangkok between march and october 1985. this study was aimed at determining the residual activity of b. sphaericus 1593 in waste water under field conditions. the larvicidal activity of b. sphaericus 1593 was found to persist for at least 5 months in artificial pools containing waste water. the populations of b. sphaericus 1593 in the test water fluctua ...19892633350
informed consent in dentistry: the impact of "who pays the bills?".this paper analyzes the concept of informed consent in dentistry from a bioethical and philosophical perspective. it is my contention that informed consent, as presently utilized in daily dental practice, might be illusory at best. after analysis of the concept in general to derive a philosophical underpinning, this basis is applied to alternate delivery systems including medicaid, capitation programs, and the "overbilling" scenario. then an approach that is respectful of the patient's autonomy ...20072634748
distribution, oxygenation, and clonogenicity of macrophages in a murine tumor.transplantable murine tumors, such as the squamous cell carcinoma growing in c3h mice, include a significant proportion of normal cells. the nature of these cells, their locations relative to the blood supply, their oxygenation status, and ability to incorporate 3h-thymidine were examined by sorting cells staining positive or negative with fluorescein isothiocyanate-conjugated goat antimouse igg. of the cells that were recovered from this tumor, 39% +/- 19 (n = 25) were igg+ cells, and this perc ...19892639726
molecular studies of human response to allergens. 19892639765
[histochemical detection of enzymes in the spinning glands of spiders].the spider's spinning apparatus equipped with numerous glands of several types appears to be a suitable model for studying tissues which produce large amounts of fibrillar proteins. heterogeneous glandular system is of special benefit for study of the function of different enzymes taking part both in the synthesis and the degradation of mentioned proteins. it is evident that the activity of the enzyme is dependent not only on the physiologic condition or a certain phase of spider's life cycle, b ...20092640359
[clinical-experimental examinations on phonetic function in edentulous patients and after insertion of total prostheses measured by the s-sound realization].lose of teeth and therapy by prosthesis interfering with the oral sectors that are necessary for s-sound articulation have an important influence on s-sound realization. hitherto, the resulting s-sound changes used to be evaluated only from a subjective point of view. the application of a complex measuring technique for s-sound analysis permitted to determine the influence of the upper and lower jaw plates on s-sound formation by experiments. in another series of experiments, it was shown that e ...20082640388
how to write your first book.many doctors have, at some time or other, the idea of writing a book. this article considers some of the practical problems involved, including dealing with publishers, the formulation of a book proposal, writing individual chapters and desirable features of computer software.19992640686
recurrent shigellosis complicating human immunodeficiency virus infection: failure of pre-existing antibodies to confer protection. 19892642653
clinical applications of recombinant human colony-stimulating factors.the differentiation and maturation of hematopoietic progenitor cells are regulated by certain growth factors. several of these glycoproteins have been characterized, and their amino acid sequences have been delineated. modern dna technology provides sufficient quantities of these hormones for testing in clinical trials. erythropoietin (epo) has been shown to increase the hemoglobin level and hematocrit in patients with end-stage renal disease. granulocyte colony-stimulating factor (g-csf) and gr ...19892642725
what every diabetes educator needs to know about hypoglycemia. 20082642796
intracellular spread of shigella flexneri associated with the kcpa locus and a 140-kilodalton protein.escherichia coli k-12 hybrids carrying both the 220-kilobase plasmid and the pure-linked kcpa locus from shigella flexneri expressed a 140-kilodalton (kda) protein which was recognized by convalescent sera from monkeys infected with s. flexneri. these hybrids were tested for the ability to produce plaques in hela cell monolayers. hybrid strains which carried both the 220-kilobase plasmid and the kcpa locus had a plaque-forming efficiency of at least 10(-4) pfu/cfu, whereas the plaque-forming eff ...19892643571
characterization of opiate binding sites on membranes of rat lymphocytes.in view of the importance of membrane receptors for the interconnection between the central nervous system and the immune system, we carried out a study to characterize opiate binding sites on membranes of rat lymphocytes. we found that mitogen-activated spleen cells, but not thymocytes, possess specific and displaceable binding sites for [3h]naloxone. the binding was equally effective and intense while using b-cell-depleted spleen cells. the binding showed two sites of saturation, one at 10 nm ...19892643626
characterization of opiate binding sites on membranes of rat lymphocytes.in view of the importance of membrane receptors for the interconnection between the central nervous system and the immune system, we carried out a study to characterize opiate binding sites on membranes of rat lymphocytes. we found that mitogen-activated spleen cells, but not thymocytes, possess specific and displaceable binding sites for [3h]naloxone. the binding was equally effective and intense while using b-cell-depleted spleen cells. the binding showed two sites of saturation, one at 10 nm ...19892643626
bilateral torsion of the normal ovary and oviduct in a young girl. 20082643670
bilateral torsion of the normal ovary and oviduct in a young girl. 20082643670
invasion of vero cells by salmonella species.the invasiveness of salmonella strains for vero cells was studied by quantitative bacteriology; the technique was more sensitive than phase contrast microscopy. all of 59 salmonella strains, of 19 different serotypes, were more invasive than escherichia coli k12. three strains of shigella were as invasive as most of the salmonella strains whereas 29 strains of e. coli, two of proteus, three of klebsiella and one of serratia were much less invasive. two citrobacter strains exhibited intermediate ...19892643706
virg, a plasmid-coded virulence gene of shigella flexneri: identification of the virg protein and determination of the complete coding sequence.on the 230-kilobase-pair (kb) virulence plasmid of shigella flexneri 2a strain ysh6000, at least seven separate genetic determinants have been identified. one of them, an approximately 4-kb region, virg, that is required for the sereny reaction, was extensively studied to examine the role of the virg region. the phenotype of a virg- mutant (m94) of ysh6000 in the cytoplasm of cultured mk cells was characterized by a kinetic study of the invading shigellae. the observed phenotype of m94 in the cy ...19892644195
chronic shigella flexneri infection preceding development of acquired immunodeficiency syndrome.shigella sp. is known to be an important cause of diarrhea in homosexual men, although chronic infection is infrequently recognized. we describe recurrent and relapsing symptomatic infection due to shigella flexneri in a human immunodeficiency virus-infected homosexual man subsequently developed acquired immunodeficiency syndrome. patients with acquired immunodeficiency syndrome may be prone to developing chronic shigellosis because of impaired intestinal cell-mediated immunity.19892644299
shigellosis and aids. report of a case and brief review of the literature.this report describes the fatal outcome of an infection with shigella flexneri in a 39-yr-old man with the acquired immunodeficiency syndrome (aids). the pertinent literature is reviewed.19892644558
ketopantoyl-lactone reductase from candida parapsilosis: purification and characterization as a conjugated polyketone reductase.ketopantoyl-lactone reductase (2-dehydropantoyl-lactone reductase, ec 1.1.1.168) was purified and crystallized from cells of candida parapsilosis ifo 0708. the enzyme was found to be homogeneous on ultracentrifugation, high-performance gel-permeation liquid chromatography and sds-polyacrylamide gel electrophoresis. the relative molecular mass of the native and sds-treated enzyme is approximately 40,000. the isoelectric point of the enzyme is 6.3. the enzyme was found to catalyze specifically the ...19892644973
role of m cells in initial antigen uptake and in ulcer formation in the rabbit intestinal loop model of shigellosis.strains of shigella flexneri with different invasive and pathogenic potentials were inoculated into the intestinal lumen of acutely ligated loops in nonimmune rabbits. after 90 min, tissues processed for ultrastructural as well as light microscopy showed that the bacilli were phagocytosed by m cells over lymphoid follicles of peyer's patches and carried in vacuoles into the epithelium. nonpathogenic as well as pathogenic strains were readily taken up regardless of the presence of the 140-megadal ...19892645214
combined therapy of enuresis alarm and desmopressin in the treatment of nocturnal enuresis.twenty-eight children with primary nocturnal enuresis were blindly allocated at random to a combination of enuresis alarm and 20 micrograms intranasal desmopressin or alarm and placebo for 2 weeks. patients received the other therapy after a 2-week treatment-free period. the combined treatment of desmopressin and alarm showed 5.1 +/- 0.4 (mean +/- sem) dry nights per week and resulted in significantly more dry nights per week during the 2 weeks of observation than placebo and alarm (4.1 +/- 0.4, ...20092646131
duplex-scanning of the deep venous drainage in the evaluation of blood flow velocity of the cerebral vascular system in infants.doppler investigations of the anterior cerebral (pericallosal) or internal carotid arteries have two major limitations: (1) flow velocity in one cerebral artery does not necessarily represent flow velocity in other cerebral arteries; (2) flow velocity spectra are influenced significantly by transducer-transferred pressure. furthermore, there are substantial pitfalls in the interpretation of arterial flow velocity data. we therefore examined doppler-shift waveforms of the deep venous drainage in ...20082646588
zinc protoporphyrin: a product of iron-deficient erythropoiesis. 20092646724
association of ki-ras with amplified dna sequences, detected in human ovarian carcinomas by a modified in-gel renaturation assay.a modified in-gel dna renaturation technique, which detects dna sequences amplified greater than 7-fold in human dna, was used to analyze gene amplification in surgical specimens of primary and metastatic ovarian carcinomas. amplified dna sequences were detected in two of eight tumors. hybridization of these samples with different oncogene probes revealed that both tumors contained an amplified ki-ras gene, which in one case was coamplified with c-myc. in one of the tumors, ki-ras was found to b ...19892647292
association of ki-ras with amplified dna sequences, detected in human ovarian carcinomas by a modified in-gel renaturation assay.a modified in-gel dna renaturation technique, which detects dna sequences amplified greater than 7-fold in human dna, was used to analyze gene amplification in surgical specimens of primary and metastatic ovarian carcinomas. amplified dna sequences were detected in two of eight tumors. hybridization of these samples with different oncogene probes revealed that both tumors contained an amplified ki-ras gene, which in one case was coamplified with c-myc. in one of the tumors, ki-ras was found to b ...19892647292
identification of cell types containing s-100b protein-like immunoreactivity in the islets of langerhans of the guinea pig pancreas with light and electron microscopy.cell types containing s-100b protein-like immunoreactivity in the islets of langerhans of the guinea pig were studied by light- and electron-microscopic immunocytochemistry using antisera to s-100b protein, insulin, glicentin, somatostatin, and pancreatic polypeptide. two types of s-100b-immunoreactive cells were identified. the first type was stellate and characterized by thin cytoplasmic processes sheathing endocrine-type cells, especially pancreatic a-cells. it was located predominantly in th ...19892647297
identification of cell types containing s-100b protein-like immunoreactivity in the islets of langerhans of the guinea pig pancreas with light and electron microscopy.cell types containing s-100b protein-like immunoreactivity in the islets of langerhans of the guinea pig were studied by light- and electron-microscopic immunocytochemistry using antisera to s-100b protein, insulin, glicentin, somatostatin, and pancreatic polypeptide. two types of s-100b-immunoreactive cells were identified. the first type was stellate and characterized by thin cytoplasmic processes sheathing endocrine-type cells, especially pancreatic a-cells. it was located predominantly in th ...19892647297
heterotopic heart transplantation: a reliable option for a select group of high-risk patients.from july 1982 through february 1988, 229 patients underwent heart transplantations at the texas heart institute, houston, 11 of whom had heterotopic transplantations. indications for the heterotopic procedure included pulmonary hypertension (eight patients) and marked body-weight mismatch (greater than or equal to 20%) between the recipient and donor (three patients). the 1-year actuarial survival rate for the heterotopic group is 80.4% compared with 77.9% for the orthotopic group. despite simi ...19892647930
nursing staff reductions: plans, process and aftermath. 20082648219
nursing staff reductions: plans, process and aftermath. 20082648219
a practical guide to using insulin. 20092648357
the role of transplantation in liver disease.liver transplantation is rapidly emerging as the most effective treatment pathway for a growing number of acute and chronic liver disease states. indications and contraindications to transplant are undergoing continuous revision and clarification as experience is accrued in the expanding number of treatment centers. for some disorders such as primary biliary cirrhosis, sclerosing cholangitis, and chronic active hepatitis with cirrhosis, the role of transplantation in patient management is obviou ...20082648619
delivered volume during high-frequency ventilation. 19892648741
new technology in infant hearing screening.early identification of hearing loss is critical in enhancing auditory and language skills in the hearing-impaired infant. various strategies for infant hearing screening are discussed. the current status of technology for screening, including auditory brainstem response audiometry, is also discussed.20092649858
emergence of highly trimethoprim-sulfamethoxazole-resistant shigella in a native american population: an epidemiologic study.resistance to trimethoprim-sulfamethoxazole (tmp-smx) emerged among shigella isolates from the navajo reservation in the southwestern united states in 1985, years after this antimicrobial agent came into common use. in the study area, tmp-smx resistance increased dramatically from 3 per cent in 1983 to 21 per cent in 1985. resistance was polyclonal and occurred in both s. sonnei and s. flexneri. no single plasmid was common to all resistant strains. however, all 28 tmp-smx resistant isolates exa ...19892650535
lead toxicity and iron deficiency in utah migrant children.we determined the frequency of presumptive iron deficiency and lead toxicity in 198 utah migrant children, ages 9-72 months, during the summer of 1985. there were no confirmed cases of lead toxicity. thirteen per cent of those tested and 30 per cent of the children ages 9-23 months were iron deficient. hematocrit determinations accurately predicted iron deficiency in only 35 per cent of the children confirmed to have this disorder via erythrocyte protoporphyrin screening.20092650572
lead toxicity and iron deficiency in utah migrant children.we determined the frequency of presumptive iron deficiency and lead toxicity in 198 utah migrant children, ages 9-72 months, during the summer of 1985. there were no confirmed cases of lead toxicity. thirteen per cent of those tested and 30 per cent of the children ages 9-23 months were iron deficient. hematocrit determinations accurately predicted iron deficiency in only 35 per cent of the children confirmed to have this disorder via erythrocyte protoporphyrin screening.20092650572
drug therapy in rheumatoid arthritis--a perspective. 20092650801
nail changes associated with systemic disease and vascular insufficiency.in some cases, nail changes may not only be the presenting sign of systemic disease, but a sensitive indicator of treatment efficacy as well. awareness of nail dystrophies and their association with underlying pathology can aid the practitioner in the diagnosis and management of the podiatric patient.20092650842
3c syndrome: third occurrence of cranio-cerebello-cardiac dysplasia (ritscher-schinzel syndrome).we report a child with an unusual pattern of malformations: severe delay in bone maturation, wide fontanelles and facial dysmorphism (evoking cleidocranial dysplasia), relative macroencephaly with cerebellar vermis hypoplasia, hypertelorism, skeletal abnormalities (1st ribs aplasia, multifocal sternal ossification centers, thin bones), septal defect, muscular waste, hypotonia and developmental delay. most of these features have been reported previously by ritscher, schinzel et al. in two sibs, w ...20092650935
[animal welfare aspects of animal slaughter].for many years animal welfare aspects of slaughtering were not discussed. but in the last ten years the research has much increased in this field. the new knowledges will be taken in account in national and european legislation. the question if ritual slaughtering without pre-slaughter stunning has to be allowed, was answered by the amendment of the animal welfare act: this form of slaughtering is now only allowed in the context of constitutional guaranteed religious liberty.20092651083
identification of an escherichia coli gene homologous to virr, a regulator of shigella virulence.virulence in shigella spp., as well as in strains of enteroinvasive escherichia coli, is regulated by growth temperature. previously, virr had been identified as the gene controlling the temperature-regulated expression of shigella virulence. since shigella spp. and e. coli are also known to share greater than 90% dna sequence homology, we sought to determine if nonpathogenic e. coli k-12 c600 contains a gene homologous to the shigella flexneri 2a gene virr. through the use of transduction and m ...19892651420
the human gastric bactericidal barrier: mechanisms of action, relative antibacterial activity, and dietary influences. 19892651535
[anxiety and the presence of the father at childbirth].the authors give a report of a follow-up the anxiety of 363 couples whereby the husband decided to be present at the childbirth and took part in the childbirth preparation courses. the anxiety state and anxiety trait in men was found to be significantly lower than in women. the data of women were compared to a matched control group consisting of 135 pregnant women. in cases where the husband was present at childbirth the anxiety state and anxiety trait of the women was considerably lower than in ...20072652033
[resistance to infection. physiology and pathology of the immune system].the contribution of observations in congenital deficiency disorders to our understanding of normal mechanisms can hardly be overestimated, as may in particular be seen in the complex field of mechanisms aiming at maintaining the individual integrity. after a brief summary of the natural lines of defense we demonstrate a few cases with typical deficiencies, i.e. of the integuments (ciliary dyskinesia syndrome), of the phagocytes (chronic granulomatous disease = cgd), of specific immune reactions ...19892652037
[hepatic mesenchymal hamartoma].a case is presented of a 10-year-old female twin with a cystic liver mass that debuted as a painless epigastric mass. the lesion was excised by hepatectomy of segments ii and iii, confirming in the review of the cavity the presence of a common mesentery with cecocolonic malposition. the postoperative course was normal and clinical and echographic study of her twin sister disclosed no anomalies. the anatomopathologic study of the lesion revealed a tumor of difficult filiation that presented featu ...20092652212
tropical infections after renal transplantation. 19892652678
androgen-regulated gene expression.while a great deal of knowledge on the mechanisms of steroid hormone regulated gene expression now exists, specific information relating to androgens is lacking. a number of experimental systems have been developed and show promise as models for molecular studies of androgen regulation. further development of these models must address the issue of whether or not the androgen receptor behaves similarly to other steroid receptors. this will require progress in the purification of the receptor itse ...19892653194
total body irradiation: single dose, fractions, dose rate. 20092653510
t-lymphocyte clones responsive to shigella flexneri.t lymphocytes from a patient with shigella flexneri dysentery and postdysenteric reactive arthritis were cloned by limiting dilution with recombinant interleukin-2 and a strain of s. flexneri different from that which had infected her. five of eight clones produced proliferated in response to the shigellae used to generate the clones. the response required irradiated syngeneic blood mononuclear cells as antigen-presenting cells. one such clone, mc12, proliferated in response to both the shigella ...19892654177
melanin chemistry and melanin precursors in melanoma. 20092654299
[a case of immediate fertility restoration following childbirth].we report an unwanted pregnancy following immediately after fulltime childbirth. we could not find previous reports of this nature in international literature. women who give bottle-feeding are even more liable to early return of ovulatory cycles than women who give breastfeeding. if a puerpera has vaginal bleeding (not lochia), there is an increased risk of ovulation as well as of endometritis. it is no longer acceptable to take impossibility to conceive immediately after delivery for granted: ...20092654662
dopplersonographic diagnosis of subclavian steal in infants with coarctation of the aorta and interrupted aortic arch.in two newborns with severe coarctation of the aorta and interrupted aortic arch, subclavian-steal was shown by angiocardiography. in both children pulsed doppler recordings were obtained in the cerebral arteries: normal forward flow during systole and diastole could be shown in the anterior cerebral arteries, both internal carotid arteries, the basilar artery and the right vertebral artery. in the left vertebral artery in both infants a negative flow indicating backflow from the brain could be ...20092654852
studies with antibodies to cultured rat glomerular epithelial cells. subepithelial immune deposit formation after in vivo injection.to investigate the role of glomerular epithelial cell (gec) membrane proteins in the in situ formation of subepithelial immune deposits, the authors raised a rabbit antiserum against gec that had been grown in culture (anti-gec). by indirect immunofluorescence (if) on normal rat kidney, anti-gec stained proximal tubular brush border (bb). after intravenous injection into animals, granular glomerular capillary wall staining for igg was present by ie and subepithelial immune deposits were identifi ...19892655461
control of diarrheal diseases.the tremendous advances made in the control of diarrheal diseases in the past few years indicate what more can be achieved. even though the lives of an estimated three quarters of a million children are being saved each year, over three million children are still dying from readily preventable diarrheal disease. the challenge is to build on the successes thus far, to learn from experience, to promote changes in health habits that will prevent diarrhea, and to make all of these activities sustain ...19892655632
role of prolactin and luteinizing hormone in regulating timing of implantation in the spotted skunk.the western spotted skunk exhibits an obligate delay of implantation lasting 200-220 days. the pituitary is essential for luteal activation. the corpora lutea, in turn, secrete the hormones necessary for blastocyst implantation. two experiments were designed to determine which pituitary hormones are responsible for increasing luteal activity and induction of implantation. forty-two pregnant skunks with delayed implanting blastocysts were treated as follows: 13 served as untreated controls, 6 rec ...20092655721
applications of immunocytochemistry to diagnostic cytopathology.immunohistochemical technique is now successfully applied to the cytologic materials. this review article describes details of staining procedures for immunocytochemistry at both light and electron microscopic levels. the clinical application of the technique includes aspiration biopsy cytology for breast lesions, thyroid lesions, lymph nodes, the nervous system, and others. the establishment of carcinoma cells in the body fluid by the demonstration of carcinoembyronic antigen (cea) and the esta ...20092656146
[treatment of cerebral hemorrhage]. 20082656221
[pemphigus vegetans, a rare variant of pemphigus vulgaris].pemphigus vegetans is a variant of pemphigus vulgaris with different clinical manifestations. diagnosis may be difficult because of the varied presentations. a 46-year-old woman with this condition had been treated for behcet's disease because of oral lesions. on admission, prior to dermatological consultation, she was thought to have an infectious disease. the diagnosis of pemphigus vegetans was confirmed by histological and immunofluorescence studies.20082656429
[pemphigus vegetans, a rare variant of pemphigus vulgaris].pemphigus vegetans is a variant of pemphigus vulgaris with different clinical manifestations. diagnosis may be difficult because of the varied presentations. a 46-year-old woman with this condition had been treated for behcet's disease because of oral lesions. on admission, prior to dermatological consultation, she was thought to have an infectious disease. the diagnosis of pemphigus vegetans was confirmed by histological and immunofluorescence studies.20082656429
inoculum size in shigellosis and implications for expected mode of transmission. 19892656880
[determination of shigella antigens in the feces of people, immunized with enteral vaccine prepared from s. flexneri antigen].the dynamic determination of the presence of the specific antigen and its activity in the excreta of humans subjected to enteral immunization with vaccine prepared from s. flexneri antigen was made in the agglutination test and neutralization test with the use of, respectively, antibody and antigenic erythrocyte diagnosticums. in the feces and urine of the vaccinees antibodies occurred less commonly and, as a rule, they were less active than those detected in dysentery patients at the correspond ...19892658436
oral shigella vaccines. 19892659269
the enteric immune response to shigella antigens.mucosal immunity to some enteropathogens occurs naturally following infection. by learning how to optimize initiation of the mucosal immune response it will be possible to develop vaccines against a wide variety of enteropathogens and their toxic products. in the past few years, we have examined stimulation of the mucosal response to shigella antigens. we have found that the mucosal memory response to shigella lps can be stimulated by oral immunization with live, but not with killed shigella. th ...19892659270
[studies on urinary c-peptide excretion in normal children and children with insulin-dependent diabetes mellitus].in 115 normal children (3 to 14 years old) and 143 children with insulin-dependent diabetes mellitus (6 to 15 years old), the urinary c-peptide immunoreactivity) was measured for evaluation of the pancreatic b cell function. the urinary c-peptide excretions during o-gtt corresponded to the change of serum c-peptide levels in normal children (n = 27) and the mean value of the excretions in younger children was significantly low. age did not significantly affect basal serum c-peptide levels (ng/ml ...20092659621
evaluation of the first 60 cases of poly hema posterior chamber lenses implanted in the sulcus.flexible lenses allow folding and inserting through a small incision. using faulkner's forceps, 60 hydrogel lenses were implanted in the sulcus through a 3.5 mm pocket incision following phacoemulsification. mean follow-up was six months. the lens was suitable for the procedure when it was properly handled. when it was not, untimely unfolding or tears occurred, necessitating prolonged maneuvering in the eye or sometimes replacement of the lens which caused increased trauma. though functional res ...20092659769
[biliary peritonitis after hepatic biopsy: favorable course with conservative medical treatment].in a 53-year-old woman a percutaneous liver biopsy was performed with tru-cut to study persistent hypertransaminasemia. the patient did not present extrahepatic cholestasis. immediately after biopsy the patient had a picture of biliary peritonitis that evolved favorably with conservative medical treatment, including hemodynamic resuscitation, antibiotic therapy, analgesic treatment and monitoring by the resuscitation service. a review is made of the literature on this complication of liver biops ...20092660206
electropherotyping of plasmid dna of different serotypes of shigella flexneri isolated in bangladesh.one hundred and twenty-five shigella flexneri strains, isolated during january-december 1984, at the dhaka treatment centre of the international centre for diarrhoeal disease research, bangladesh, were serotyped using absorbed rabbit antisera specific for all type- and group-factor antigens, as well as a group of ten mouse and rat monoclonal antibodies. electropherotypes of the plasmid deoxyribonucleic acid (dna) were also determined. s. flexneri 2a was the predominant serotype followed by 3b, 1 ...19892661251
renal allograft rejection: possible involvement of lymphokine-activated killer cells.human renal allograft tissue was recovered at transplant nephrectomy from three patients with irreversible loss of graft function. this tissue was disaggregated and separated into two fractions on the basis of particle size. fraction 1 contained glomeruli and developed a mixed outgrowth containing adherent epithelial and mesangial cells after a limited period of culture. fraction 2 contained fragments of renal tubules and produced monolayers of tubular epithelial cells during culture. a populati ...19892661417
inhibition of proteoglycan synthesis alters extracellular matrix deposition, proliferation, and cytoskeletal organization of rat aortic smooth muscle cells in culture.arterial proteoglycans have been implicated in several important physiological processes ranging from lipid metabolism to regulation of smooth muscle cell growth. vascular smooth muscle (vsm) cells are the major producers of proteoglycans in the medial layer of blood vessels. to study functional consequences of alterations in vsm proteoglycan metabolism we used 4-methylumbelliferyl-beta-d-xyloside to inhibit proteoglycan synthesis in primary and early passage cultures of rat aortic smooth muscle ...19892661564
a french research programme: santé-maladie-société (1984-1988). 20092662421
[biological properties of bacteria of the species shigella flexneri].some biological properties of s. flexneri have been studied. the strains of this bacterial species have been shown to produce dnaase in 98.8 +/- 0.77% of cases and rnaase in 97.4 +/- 1.5% of cases. the capacity for the positive reaction with congo red as early as after 24-hour incubation in the thermostat has proved to be characteristic of s. flexneri (91.1 +/- 3.6%). if stored at 4 degrees c in semiliquid agar, s. flexneri cultures have been found to retain their capacity for producing the abov ...19892662686
lineage-specific gene rearrangement/deletion: a nonconservative model.for the lymphocytic descendants of the hematopoietic differentiation pathway, characteristic gene rearrangements result in deletions of significant portions of chromosome regions specifying lymphocyte-specific gene products on either or both chromosomes of each involved pair. molecular mechanisms facilitating the rearrangement/deletion events have been elegantly and fruitfully elaborated in the years since the first documentation of their occurrence by hozumi and tonegawa (n. hozumi and s. toneg ...19892663139
elimination of malignant clonogenic breast cancer cells from human bone marrow.autologous bone marrow transplantation is a promising approach to the treatment of breast cancer but is at present limited to patients without bone marrow metastases. to eliminate malignant clonogenic breast cancer cells from normal human bone marrow, immunomagnetic separation has been combined with chemoseparation using 4-hydroperoxycyclophosphamide. breast cancer cell lines have been mixed with a 10-fold excess of irradiated human bone marrow from normal donors. mixtures have been incubated wi ...19892663144
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