Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| genome-wide transcriptome analysis reveals extensive alternative splicing events in the protoscoleces of echinococcus granulosus and echinococcus multilocularis. | alternative splicing (as), as one of the most important topics in the post-genomic era, has been extensively studied in numerous organisms. however, little is known about the prevalence and characteristics of as in echinococcus species, which can cause significant health problems to humans and domestic animals. based on high-throughput rna-sequencing data, we performed a genome-wide survey of as in two major pathogens of echinococcosis-echinococcus granulosus and echinococcus multilocularis. our ... | 2017 | 28588571 |
| prevalence of cystic echinococcosis in iran: a systematic review and meta-analysis. | as a significant zoonosis, cystic echinococcosis (ce) is endemic in some parts of the world, such as the middle east. there are studies on the prevalence of this infection in animal and human reservoirs in iran; hence, we conducted this meta-analysis to elucidate the prevalence of ce in iran. english (pubmed, scopus, web of science, science direct and google scholar) and persian (magiran, iran medex, iran doc and sid) databases were explored. in the case of definitive, animal and human intermedi ... | 2017 | 28589871 |
| primary sacral hydatid cyst causing cutaneous fistula. | echinococcus granulosus and echinococcus multilocularis are the causes of hydatid disease and the main characteristic is endemic. generally, it affects the liver and lungs. spinal hydatidosis accounts for less than 1% of the cases. vertebral hydatidosis is usually silent and a slowly progressive disease with a long latent period. another rare form is the primary sacral hydatid cyst. generally, patients suffer from back pain and neural compression symptoms. a 43-year woman was admitted with left ... | 2017 | 28599696 |
| characterization of glutathione s-transferase and its immunodiagnostic potential for detecting taenia multiceps. | taenia multiceps is a widespread zoonotic tapeworm parasite which infects cloven-hoofed animals around the world. animal infection with coenurus cerebralis, the coenurus larvae of t. multiceps (tm), is often fatal, which is a major cause of economic losses in stockbreeding. this study amplified the glutathione s-transferase (gst) gene from the total rna of c. cerebralis. the resulting protein, tm-gst, consisted of 201 amino acids, and had a predicted molecular mass of 23.1kda. its amino acid seq ... | 2017 | 28606321 |
| coprodiagnosis of echinococcus granulosus infection in dogs from ankara, turkey. | the present study were undertaken to compare two isolation techniques (centrifugal flotation and sedimentation) for recovering taeniid eggs from faecal samples, to identify e. granulosus dna from taeniid eggs by pcr, and to determine the prevalence of e. granulosus in dogs in villages. faecal samples were collected from 100 dogs in ankara province. taenia spp. eggs were found in 27% of dogs faeces. echinococcus granulosus-specific pcr was obtained in 14 (51.85%) of the taeniid eggs-positive samp ... | 2017 | 28606323 |
| epidemiological and clinical aspects of patients with hydatid cyst in iran. | hydatid cyst is one of the most common zoonotic diseases occurs due to infection with larval stage of echinococcus granulosus parasite. based on epidemiological reasons, world health organization has introduced iran as a hyperendemic region. this study aims to investigate the clinico-epidemiological characteristics of patients with hydatid cyst in iran. we used information registered in the surveillance system of the iranian ministry of health and medical education attributed to mazandaran provi ... | 2017 | 28615839 |
| epidemiological investigation and risk factors of echinococcus granulosus in yaks (bos grunniens), tibetan pigs and tibetans on qinghai tibetan plateau. | echinococcus granulosus (e. granulosus) is a diverse zoonotic parasite and causes cystic echinococcosis (ce) disease in humans and livestock. however, scare information is available about the epidemic situation of e. granulosus infection in yaks, tibetan pigs and native tibetans on the qinghai tibetan plateau. therefore, a study was carried out to find prevalence and risk factors of e. granulosus in yaks, tibetan pigs and tibetans. serum samples from yaks (1371), tibetan pigs (454) and tibetans ... | 2017 | 28624512 |
| immunodiagnostic value of echinococcus granulosus recombinant b8/1 subunit of antigen b. | cystic echinococcosis (ce), as a chronic parasitic disease, is a major health problem in many countries. the performance of the currently available serodiagnostic tests for the diagnosis of ce is unsatisfactory. | 2017 | 28630382 |
| balb/c mice immunity to hydatidosis induced by in-vitro reared echinococcus granulosus adult worm antigens. | echinococcosis is a zoonotic parasitic disease caused by the larval stage of echinococcus granulosus. several native and recombinant antigens, derived from different stages of e. granulosus life cycle, have been used for vaccine trials. in vitro reared adult worms are good candidates for vaccination as they do not produce fertile egg/s and do not have any risk of contamination for researchers. | 2017 | 28630383 |
| presentation of secondary parasitic infection 37 years after primary infection. | echinococcus granulosus (eg) is a neglected pathology that causes cystic echinococcosis and primarily affects the liver and lung. eg infects ~6 million worldwide and mortality is quoted as 2-4% per 100 000 inhabitants. the increase in human traffic from endemic regions demands clinician's awareness. dogs are the most common definitive host for the eg tapeworm. human infection requires ingestion of fecal parasitic eggs. primary infection causes cysts to appear in affected organs, rupture of which ... | 2017 | 28630663 |
| genetic diversity and phylogenetic analysis of eg95 sequences of echinococcus granulosus: implications for eg95 vaccine application. | to analyse the genetic variability of eg95 sequences and provide guidance for eg95 vaccine application against echinococcus granulosus (e. granulosus). | 2017 | 28647192 |
| recurrence of cystic echinococcosis in an endemic area: a retrospective study. | cystic echinococcosis (ce) is a chronic, complex and neglected zoonotic disease. ce occurs worldwide. in humans, it may result in a wide spectrum of clinical manifestations, ranging from asymptomatic infection to fatal disease. clinical management procedures have evolved over decades without adequate evaluation. despite advances in surgical techniques and the use of chemotherapy, recurrence remains one of the major problems in the management of hydatid disease. the aim of this study was to deter ... | 2017 | 28655301 |
| an unusual cause of chest pain: an isolated huge cardiac hydatid cyst. | hydatid disease is a human parasitic infection caused by the larval stage of echinococcus granulosus. the most common locations for hydatid cysts are the liver and lungs. cardiac involvement is rare, and isolated cardiac hydatid cysts are even more unusual. we report the case a 48-year-old female patient with an isolated huge cardiac hydatid cyst involving both the left ventricular free wall and the pericardium, and presenting with atypical chest pain. © 2017 wiley periodicals, inc. j clin ultra ... | 2017 | 28656619 |
| complicated hydatid cyst of ulna- a rare case report. | although hydatidosis is not uncommon in tropical countries, still bony involvement is comparatively rare. the aetiological agent is echinococcus granulosus, a parasite belonging to cestode group with dog as definitive host and man as incidental host. we present a case of young male, who consulted us for painless, multiple swellings in his right forearm of three years duration, with restricted wrist movements. on examination multiple non tender, soft to firm swellings were noted with restricted t ... | 2017 | 28658863 |
| multiorgan echinococcus infection: treatment of an immigrant in the united states. | we discuss the clinical presentation and management of a 36-year-old woman presenting with a 12-year history of recurrent hydatid disease, a disease caused by echinococcus granulosus and other echinococcal species, which is rarely seen in the contiguous united states. she has had multiple procedures since her diagnosis in 2005 and is still closely being followed for possible disease recurrence. | 2017 | 28660127 |
| identification of ige and igg1 specific antigens in echinococcus granulosus cyst fluid. | cystic echinococcosis (ce) is an anthropozoonotic disease with worldwide distribution and is caused by the cestode echinococcus granulosus. anaphylactic shock induced by ce rupture is a serious complication especially in patients with hydatid infections, as the resulting leakage of fluid contains highly toxic endogenous antigen. we aimed to isolate and identify the antigens of specific ige and igg1 (sige and sigg1) in e. granulosus cyst fluid (egcf). crude antigen for egcf was prepared from e. g ... | 2017 | 28678921 |
| liver hydatid cyst with cutaneous fistulization to the right breast: a case report, management, and literature review. | echinococcus granulosus is the most common tapeworm causing hydatid disease in humans. its least-encountered complication is cutaneous fistulization. omentoplasty, cyst, and fistulous tract drainage revealed successful in the management of this complication. such intervention can be an alternative when conservative management fails, and a minimally aggressive procedure is required. | 2017 | 28680601 |
| knowledge, attitudes, and practices regarding cystic echinococcosis and sheep herding in peru: a mixed-methods approach. | the parasitic disease, cystic echinococcosis (ce), is prevalent in low-income, livestock-raising communities and 2000 new people will be diagnosed this year in south america alone. the disease usually passes from livestock to dogs to humans, making it a zoonotic disease and part of the one health initiative. control of ce has been infamously difficult; no endemic areas of south america have succeeded in maintaining sustainable eradication of the parasite. for the current study, we aimed to gain ... | 2017 | 28683741 |
| hydatid disease of the spine: a rare case. | hydatid disease or hydatidosis is the most widespread zoonosis caused by echinococcus granulosus. liver and lungs are the most common sites. bone involvement is rare and reported in 0.5%-4% with spinal involvement reported in 50% of these cases. we present a case of spinal hydatidosis in a 35-year-old male presenting with lower extremity weakness and numbness. magnetic resonance imaging (mri) of the spine showed multiple cystic lesions at the t9-t11 level with involvement of the paraspinal muscl ... | 2017 | 28694603 |
| primary paraspinal hydatidosis causing acute paraplegia. | the zoonotic infection hydatidosis is caused by the tapeworm cestode, echinococcus granulosus. though considered endemic in india where association of humans with sheep and dogs form part of the livelihood, primary skeletal muscle involvement of the disease is an extremely rare event. we report a case of primary paraspinal hydatidosis with extradural extension causing acute paraplegia. excision of the cyst and decompression of the cord was done along with albendazole therapy. paraspinal hydatid ... | 2017 | 28694639 |
| detection of echinococcus granulosus antigen by a quantum dot/porous silicon optical biosensor. | highly sensitive labeled detection of echinococcus granulosus using colloidal quantum dots (qds) based on a porous silicon bragg mirror sensor are demonstrated. rabbit anti-p38 labeled cdse/zns qds was infiltrated in porous silicon pores immobilized egp38 antigen. qd-antibodies are specifically bound to antigens linked covalently to the pore walls of psi after the immune reaction. by the design of the transfer matrix method and the preparation of the electrochemical etching method, the fluoresce ... | 2017 | 28717581 |
| genetic characterization of human hydatid cysts shows coinfection by echinococcus canadensis g7 and echinococcus granulosus sensu stricto g1 in argentina. | human cystic echinococcosis caused by the larval stage of echinococcus granulosus sensu lato (s.l.) is a highly endemic disease in the province of neuquén, patagonia, argentina. human infections with e. granulosus sensu stricto (s.s.) g1 and echinococcus canadensis g6 were reported in neuquén in previous studies, whereas four genotypes were identified in livestock: g1, g3, g6, and g7. the aim of this study was to identify the genotypes of e. granulosus s.l. isolates from humans of neuquén provin ... | 2017 | 28721526 |
| cystic echinococcosis in turkana, kenya: the role of cross-sectional screening surveys in assessing the prevalence of human infection. | cystic echinococcosis (ce) is a neglected zoonotic disease caused by echinococcus granulosus. infection leads to formation of cysts within the viscera of the human host. in the 1980s, the transhumant population of northwest turkana, kenya, was found to have the highest prevalence of ce in the world. in 1983, amref health africa and the kenya medical and research institute launched a ce control program in northwest turkana, screening and treating the local people. this epidemiological study of ce ... | 2017 | 28722634 |
| musculoskeletal echinococcus infection as a rare first presentation of hydatid disease: case report. | hydatid disease (hd) is a cosmopolitan parasitosis caused by echinococcus granulosus that can potentially affect any part of the human body. liver and lungs are the most frequent localizations. primary musculoskeletal hydatidosis are seldom reported in literature and their incidence is unknown. | 2017 | 28725269 |
| the echinococcoses in asia: the present situation. | human alveolar and cystic echinococcosis, caused by the accidental ingestion of eggs of the tapeworms echinococcus multilocularis and echinococcus granulosus sensu lato, respectively, are endemic in asia. various echinococcus species are maintained in domesticated and/or wild mammals through predator-prey interactions. molecular analysis is used to help differentiate infecting parasite species and genotypes, with the goal of better understanding parasite life cycles in order to aid in the planni ... | 2017 | 28728830 |
| identification of universal diagnostic peptide candidates for neglected tropical diseases caused by cestodes through the integration of multi-genome-wide analyses and immunoinformatic predictions. | neglected tropical diseases caused by helminth infections currently affect millions of people worldwide. among them, there are three tapeworm species of outstanding importance: echinococcus granulosus, e. multilocularis, and taenia solium, which are responsible for cystic echinococcosis, alveolar echinococcosis, and cysticercosis, respectively. despite several attempts, there is still a need for an effective and low-cost serological diagnostic test that can be used in endemic countries. in the p ... | 2017 | 28728879 |
| the excretory-secretory products of echinococcus granulosus protoscoleces directly regulate the differentiation of b10, b17 and th17 cells. | excretory-secretory products (esps) released by helminths are well-known to regulate t cell responses in the host. however, their direct influence in the differentiation of naïve t cells, and especially b cells, remains largely unknown. this study investigated the effects of echinococcus granulosus protoscoleces esps (egpsc-esps) on the differentiation of il-10-producing b cells (b10), il-17a-producing b cells (b17) and th17 cells. | 2017 | 28732522 |
| primary renal echinococcosis. | echinococcosis is a parasitic infection caused by the larval stage of a cestode echinococcus granulosus and is endemic in sheep farming regions of developing countries. it manifests as hydatid cyst and most commonly is found in liver followed by lungs. renal hydatid cyst is rare and amounts for 2% of all cases. there are no specific clinical manifestations, and hence diagnosis of renal hydatid disease is missed out easily without imaging. we report a case of 50-year-old female who had 6 months h ... | 2017 | 28761236 |
| molecular and morphological characterizations of echinococcus granulosus from human and animal isolates in kashan, markazi province, iran. | one of the most important zoonotic helminths in the world is known as echinococcus granulosus. different strains of the e. granulosus have been described based on morphological and molecular characterizations, however, there is limited information regarding the characteristics of the phenotypes and genotypes of e. granulosus in iran. | 2017 | 28761477 |
| road killed carnivores illustrate the status of zoonotic helminthes in caspian sea littoral of iran. | carnivore carcasses on the roads can be regarded as study materials in parasitology and eco-epidemiology. stray carnivores such as dogs and cats are known to harbor so many different pathogens like zoonotic helminthes. the current investigation, apparent the status of the helminthic parasites found in road killed carnivores from different parts of guilan province north of iran. | 2017 | 28761483 |
| evaluation of microsatellites markers to discriminate four main taeniid tapeworms of dogs. | echinococcus granulosus, taenia multiceps, taenia ovis and taenia hydatigena are among the most prevalent taeniid species of dogs. these tapeworms infect ruminant and humans as intermediate hosts and domestic/wild carnivores as the definitive hosts. molecular tools using hypervariable microsatellite regions might provide more information about parasite variation. highly variable and specific tools are needed for transmission tracking studies of canine echinococcosis as an essential element for i ... | 2017 | 28761491 |
| the non-resolving lung cavity: a case of pulmonary cystic echinococcosis. | the authors report a case of a 20-year-old woman who was diagnosed with pulmonary cystic echinococcosis. she was admitted to hospital with a 1-week history of unresolving cough, coloured sputum with occasional haemoptysis and fever despite oral antibiotics. radiology revealed a cavitating right lower lobe lung abscess. after 4 weeks of treatment, follow-up radiology showed incomplete resolution. bronchoscopy revealed a white, avascular cystic lesion in the right lower lobe and serology testing f ... | 2017 | 28765482 |
| the impact of socio-cultural factors on transmission of taenia spp. and echinococcus granulosus in kosovo. | echinococcus granulosus sensu latu (s.l.) and taenia hydatigena are common parasites of ruminant intermediate hosts in the balkans. transmission is linked mainly to home slaughtering and the feeding of infected organs to dogs. in kosovo, many old sheep are slaughtered particularly during eid al-adha (feast of sacrifice). to determine whether this tradition could affect parasite transmission, we compared the probability of 504 dogs to contract taenid infections after deworming during one period b ... | 2017 | 28799892 |
| unusual locations of hydatid disease: a 10-year experience from a tertiary reference center in western turkey. | hydatid disease is an endemic parasitic infection caused by echinococcus granulosus mostly seen in the mediterranean countries. the most affected organ is the liver, however hydatidosis can be found anywhere in the human body. | 2017 | 28807340 |
| effects of trigonelline inhibition of the nrf2 transcription factor in vitro on echinococcus granulosus. | the aim of this study was to investigate the impact of trigonelline (trg) on echinococcus granulosus, and to explore the inhibition impact of nuclear factor erythroid-2-related factor 2 (nrf2) signaling pathway on e. granulosus protoscoleces. echinococcus granulosus protoscoleces were incubated with various concentrations of trg, and then nrf2 protein expression and its localization in protoscoleces were detected by western blot analysis and immunofluorescence assay, respectively. reactive oxyge ... | 2017 | 28810706 |
| bortezomib initiates endoplasmic reticulum stress, elicits autophagy and death in echinococcus granulosus larval stage. | cystic echinococcosis (ce) is a worldwide distributed helminthic zoonosis caused by echinococcus granulosus. benzimidazole derivatives are currently the only drugs for chemotherapeutic treatment of ce. however, their low efficacy and the adverse effects encourage the search for new therapeutic targets. we evaluated the in vitro efficacy of bortezomib (bz), a proteasome inhibitor, in the larval stage of the parasite. after 96 h, bz showed potent deleterious effects at a concentration of 5 μm and ... | 2017 | 28817601 |
| proteomic analysis of taenia hydatigena cyst fluid reveals unique internal microenvironment. | taenia hydatigena is a parasitic flatworm that is widely distributed around the world. using ms/ms, the proteome of t. hydatigena cyst fluid (cf) was profiled and a total of 520 proteins were identified, 430 of which were of sheep origin. t. hydatigena shared 37 parasite-origin and 109 host-origin cf proteins with echinococcus granulosus. compared with e. granulosus, t. hydatigena had much more cf proteins associated with amino acid synthesis and complement cascades. in addition, glutamate metab ... | 2017 | 28837787 |
| kinetic studies of eggst1, a mu class glutathione s-transferase from the cestode parasite echinococcus granulosus. | glutathione transferases (gsts) comprise a major detoxification system in helminth parasites, displaying both catalytic and non-catalytic activities. the kinetic mechanism of these enzymes is complex and depends on the isoenzyme which is being analyzed. here, we characterized the kinetic mechanism of reggst1, a recombinant form of a cytosolic gst from echinococcus granulosus (eggst1), which is related to the mu-class of mammalian enzymes, using the canonical substrates glutathione (gsh) and 1-ch ... | 2017 | 28842127 |
| surgically managed human cystic echinococcosis in north-eastern iran: a single center's experience from 2001 to 2008. | cystic echinococcosis (ce) is a zoonotic parasitic disease caused by the tapeworm echinococcus granulosus. although ce has a large geographic distribution, data are lacking on the frequency of infection and epidemiology of ce in many endemic areas of the world, including the middle east. demographic and clinical information on surgically managed human ce cases were evaluated from a referral hospital in north-eastern iran for the years 2001-2008. of the 400 ce cases, 218 (54.5%) were male. the me ... | 2017 | 28848297 |
| ruptured pulmonary hydatid cyst: a case report. | ruptured pulmonary hydatid cyst (phc) is an important clinical problem in endemic areas to echinococcal infection. herein we present a rare case of ruptured phc in an adolescent boy that was misdiagnosed as pulmonary tuberculosis in local health center. when sputum specimen was stained by acid-fast staining for detection of mycobacterium tuberculosis, hooklets of echinococcus granulosus were observed. a simple chest x-ray showed a multilobulated mass in the lower part of the left lung. computed ... | 2017 | 28848299 |