Publications
Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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cloning and structural characterization of the genes coding for adenosylcobalamin-dependent methylmalonyl-coa mutase from propionibacterium shermanii. | the structural genes coding for both subunits of adenosylcobalamin-dependent methylmalonyl-coa mutase from the gram-positive bacterium propionibacterium shermanii have been cloned, with the use of synthetic oligonucleotides as primary hybridization probes. the genes are closely linked and are transcribed in the same direction. nucleotide sequence analysis of 4.5 kb of dna encompassing both genes allowed us to infer the complete amino acid sequence of the two subunits: the beta-subunit is the pro ... | 1989 | 2569861 |
takayasu arteritis presenting as retinal and vertebrobasilar ischemia. | a young woman presented with a 4-month history of retinal and vertebrobasilar ischemia. angiography demonstrated narrowing of major branches of the aortic arch. intractable, severe retroorbital pain of the right eye developed after a middle cerebral artery stroke. during 4 weeks of aggressive immunosuppressive therapy including iv high dose bolus corticosteroids and pulse cyclophosphamide, her neurologic deficit improved transiently, but her retroorbital pain persisted. she died of staphylococca ... | 2008 | 2570149 |
similarities in the repair kinetics of sublethal and potentially lethal x-ray damage in log phase chinese hamster v79 cells. | we have compared the repair kinetics of x-ray-induced sublethal damage (sld) and potentially lethal damage (pld) in v79 cells during postirradiation incubation in growth medium at 37 degrees c. kinetics of sld repair were studied by dose fractionation (d1 + d2 = 2 + 2, 4 + 2, 4 + 4, 10 + 4 and 10 + 7 gy). kinetics of pld repair were studied by incubating cells with 0.5 m hypertonic saline (hs) for 20 min at various times after irradiation. the repair of sld, after 2, 4 and 10 gy, was complete in ... | 2008 | 2570810 |
hydrogen peroxide mutagenicity towards salmonella typhimurium. | in bioassays conducted under controlled, comparable conditions, weak direct mutagenicity responses were observed for hydrogen peroxide in the standard (ames test) agar plate incorporation bioassay with salmonella typhimurium strains ta97, ta98, ta102, and ta1537, in a 20 min preincubation test with strains ta97, ta98, ta100, ta102, ta1537, and ta1538, and in a liquid incubation modification using strain ta1537. these results conclusively demonstrate that hydrogen peroxide is a weak mutagen, espe ... | 1989 | 2572065 |
bacteroides loeschei pk1295 cells express two distinct adhesins simultaneously. | bacteroides loeschei synthesizes two distinct adhesins that mediate its coaggregation with streptococcus sanguis 34 and actinomyces israeli pk14. streptococcal adhesin-specific and actinomyces adhesin-specific monoclonal antibodies were used to prepare antibody-coated 5- or 10-nm gold particles. these were used in immunoelectron microscopic studies to establish that essentially all bacteroides cells in a population express both adhesins. in general, the two sizes of gold particles representing e ... | 1989 | 2572563 |
influence of infused beta-adrenergic agonists on porcine blood metabolites and catecholamines. | anesthetized pigs were infused sequentially with increased concentrations of beta-adrenergic agonists. at selected times during infusion, blood pressure, heart rate and plasma concentrations of free fatty acids (ffa), glycerol, glucose, lactate, norepinephrine, epinephrine and dopamine were measured. azaperone, a drug used to calm the pigs before anesthesia, caused hypotension and bradycardia but did not affect plasma metabolites. infusion of norepinephrine, epinephrine, isoproterenol or clenbut ... | 1989 | 2572576 |
restriction fragment length polymorphism of the human insulin receptor gene among mexican americans. | recently, we examined a restriction fragment length polymorphism (rflp) at the insulin receptor locus in mexican americans. this rflp can be detected using the restriction endonuclease rsa i, and has three alleles of 3.4 kb, 6.2 kb, and 6.7 kb. our data suggested that the 3.4 kilobase pair (kb) allele may be associated with type ii (non-insulin dependent) diabetes mellitus in mexican americans. we initiated studies to identify additional polymorphisms at the insulin receptor locus that might be ... | 1989 | 2573118 |
modulation of the autonomic control of the failing heart. | the failing heart operates with an abnormal combination of heart rate, stroke volume, and enddiastolic volume. this mismatch becomes more evident during exercise of patients with heart failure, when an increase in cardiac output is achieved with higher heart rate, a lower stroke volume and a higher enddiastolic volume. using the beta 1-adrenoceptor partial agonist xamoterol which lacks beta 2-adrenoceptor agonism the response of the heart to sympathetic stimulation can be modulated. at rest and ... | 1989 | 2573339 |
on the mechanism of positive inotropic effects of alpha-adrenoceptor agonists. | the positive inotropic effect of the alpha 1-adrenoceptor agonist phenylephrine is accompanied by an increase in the presumed second messengers inositol 1,4,5-trisphosphate (1,4,5-ip3) and inositol 1,3,4,5-tetrakisphosphate (1,3,4,5-ip4). both 1,4,5-ip3 and 1,3,4,5-ip4 sensitize myocardial contractile proteins in chemically skinned fibers. in addition to the ca++ releasing effect of 1,4,5-ip3 from the sarcoplasmic reticulum the ca++-sensitizing effect of the inositol phosphates may play a role i ... | 1989 | 2573342 |
glutamine synthetase and glutaminase activities in various hepatoma cells. | glutamine synthetase and glutaminase activities in a series of hepatoma cells of human and rat origins were determined for comparison with normal liver tissues. marked decrease in glutamine synthetase activity was observed in the tumor cells. phosphate-dependent and phosphate-independent glutaminase activities were increased compared with those from normal liver tissues. well coupled mitochondria were isolated from huh 13 line of human hepatoma cells and human liver. oxypolarographic tests showe ... | 1989 | 2573354 |
neurotransmitters in the brain. | 2008 | 2573362 | |
structure-activity relationships as a response to the pharmacological differences in beta-receptor ligands. | with a few notable exceptions, beta-receptor ligands (agonists and antagonists) belong to the aryl- or heteroaryl-ethanolamine series and to the aryl- or heteroaryl-oxypropanolamine series. structure-activity relationships for beta-adrenergic agonists show that a secondary amine in the phenylethanolamine side chain ending is essential for receptor stimulation. the 3,4-dihydroxyphenyl groups may be replaced by "phenol equivalents" (-ch2oh, -nhconh2, -choh, -nhso2ch3). in contrast, substitution at ... | 1989 | 2573372 |
reduction of beta-adrenergic receptors can explain the lack of rebound effect after tertatolol withdrawal. | tertatolol is a potent beta-blocker with no intrinsic sympathomimetic activity (isa) or beta 1/beta 2 receptor subtype selectivity. we provide evidence that tertatolol competitively inhibits beta-adrenergic receptors (beta-ar) and induces a marked and persistent reduction of their number. this has been consistently found in vitro and in vivo. the in vitro study showed that the receptor reduction by tertatolol was rapid (about 1 h at 37 degrees c), slowly reversible and independent of isa. this e ... | 2008 | 2573373 |
effects of long-term antihypertensive treatment with tertatolol on diastolic function in hypertensive patients with and without left ventricular hypertrophy. | we assessed the effects of long-term antihypertensive treatment with 5 mg tertatolol, a noncardioselective beta-blocker, on left ventricular hypertrophy (lvh) and diastolic function. fifteen hypertensive patients were selected as good responders to previous treatment with tertatolol (supine blood pressure less than 140/90 mm hg). they were divided into 2 groups: group 1 with lvh (n = 6) and group 2 without lvh (n = 9). after a one month wash-out period, all patients received 5 mg tertatolol once ... | 2008 | 2573376 |
methadone maintenance programmes and aids. | 2008 | 2574792 | |
prea4 mrna distribution in brain areas. | the a4 amyloid precursor gene of alzheimer's disease (prea4 gene, app gene, pad gene) gives rise to three different transcripts, which are generated by alternative splicing. the three transcripts are prea4695, prea4751 and prea4770, according to the number of amino-acids in the primary translation product. previous expression studies did not discriminate between prea4751 and prea4770. we have analyzed the distribution of prea4 transcripts in four cortical brain areas in a way that allows us the ... | 2008 | 2574867 |
[effects of bombesin on gastrin, somatostatin, glucagon and acid secretion from isolated rat stomach in vitro]. | effects of bombesin on the secretion of gastric acid and gastro-intestinal hormones were investigated in isolated perfused rat stomach. bombesin (intra-arterial, 2 x 10(-10) mol/l, 0.3 ml/min) stimulated gastric acid secretion from basal 2.50 +/- 0.05 x 10(-1) to 8.40 +/- 1.50 x 10(-1) meq/min (p less than 0.001). exogenous addition of pentagastrin did not potentiate this effect of bombesin. bombesin induced twice releasing of gastrin and somatostatin in portal effluent but inhibited glucagon se ... | 1989 | 2574916 |
[umeå, my little big city]. | 2008 | 2574927 | |
central and peripheral actions of alpha 2-adrenergic agonists on renal function in long-evans and brattleboro rats. | the effects of 3 alpha 2-adrenergic receptor agonists on renal function in vasopressin (avp)-deficient brattleboro (di) rats were evaluated. the aim of this study was to determine the relative contribution of central versus peripheral alpha 2-adrenoceptors in mediating diuresis and natriuresis, as well as the role of alpha 2-adrenoceptors in antagonizing the actions of avp. in addition to the studies of renal function, the effects of avp deficiency on renal alpha 2-adrenoceptor affinity and numb ... | 1989 | 2575260 |
inositol 1,4,5-trisphosphate-induced calcium mobilization is localized in xenopus oocytes. | injection of inositol 1,4,5-trisphosphate (ins(1,4,5)p3) into the animal pole of xenopus oocytes induced membrane depolarization due to the internal mobilization of calcium, which activates a chloride conductance. repetitive injections of ins(1,4,5)p3 results in desensitization probably as a result of depletion of the internal store of calcium. desensitization was restricted to the region surrounding the site of injection. injection of ins(1,4,5)p3 at one position induced desensitization, which ... | 2008 | 2575752 |
study of the negative inotropic action of somatostatin. | somatostatin was evaluated as a chronotropic and inotropic agent in isolated, spontaneously beating guinea-pig atria. somatostatin (3 x 10(-5)-1 x 10(-3) mm) caused a concentration-dependent negative inotropic effect and a small reduction of atrial rate. the negative inotropic effect of somatostatin was evaluated at different concentrations of extracellular calcium, on the positive inotropic response induced by calcium and on the positive chronotropic response induced by adrenaline. small, nonsi ... | 1989 | 2575886 |
[what intensity of the incisional pain in the postoperative period?]. | 2008 | 2576331 | |
comparison of a vasodilating beta-blocker and a cardioselective beta-blocker in long-term treatment of hypertension: a european multicentre study. | the therapeutic effectiveness and safety of indenolol, a vasodilating beta-blocker with beta 2-agonism, was compared with that of atenolol, a cardioselective beta-blocker, in a 1-year double-blind trial. a total of 143 hypertensive patients (diastolic blood pressure 95-115 mmhg after 1 month of placebo) were randomly allocated to either atenolol, 50 mg/day, or indenolol, 60 mg/day. if the target diastolic blood pressure (less than or equal to 90 mmhg) was not reached after 1 month, the beta-bloc ... | 2008 | 2576667 |
[barium currents through single calcium channels of a nerve cell membrane]. | 2008 | 2580683 | |
medium- and long-latency responses to displacements of the ankle joint in patients with spinal and central lesions. | in order to elucidate further the possible pathways and the functional significance of long-loop reflexes we recorded short-, medium- and long-latency responses from leg muscles in 27 patients with spinal lesions, 20 patients with central lesions of the internal capsule or cerebral hemisphere, and in 18 control patients with frontal or occipital lesions without motor or sensory disturbances. our normal population included 50 subjects, who were age and sex matched to the patients. the mean latenc ... | 2008 | 2580691 |
a model for the resistance of the proton channel formed by the proteolipid of atpase. | the conductance observed for single proton channels formed by proteolipids of atpase (schindler and nelson 1982) is rationalized in terms of a hydrogen bonded network model. a simple algebraic expression for the resistance predicted for such a model is presented and the results are compared to the experimental observations. the comparison suggests that the conduction involves a series of bound water molecules and perhaps amino acid side groups. | 2008 | 2580699 |
measurement of igg in equine blood by immunoturbidimetry and latex agglutination. | this paper describes the quantitative measurement of igg concentrations in equine blood/serum by turbidimetric analysis and the qualitative assessment using latex agglutination. the concentration of igg in foal serum measured by turbidimetry correlated well with the results obtained by radial immunodiffusion (r = 0.91) and the gamma-globulins estimated from the electrophoresis of serum on cellulose acetate (r = 0.92). the method, using antibody-coated latex beads, to detect foals with serum igg ... | 1985 | 2580703 |
structural analysis of the o-glycosidically linked core-region oligosaccharides of human meconium glycoproteins which express oncofoetal antigens. | glycoproteins were extracted from meconium samples of group o neonates of secretor type by pronase digestion followed by precipitation in 67% aqueous ethanol and separated into ii antigen enriched and depleted fractions by affinity chromatography. the latter fraction strongly expressed the oncofoetal antigens recognised by natural antibodies in mouse sera and the hybridoma antibody fc 10.2, and this activity was enhanced after mild acid hydrolysis to remove sialic acid and fucose residues. oligo ... | 1985 | 2580706 |
cardiac performance in hyperthyroidism assessed by systolic time intervals and radionuclide ventriculography. | systolic time intervals (sti) and radionuclide ventriculography (rnv) were used in the assessment of cardiac performance in 22 patients with hyperthyroidism before and after antithyroid treatment. sti as well as rnv showed enhanced myocardial contractility which was normalized after antithyroid treatment. beta-blocker treatment did not influence the hypercontractility in hyperthyroidism. this implies that beta-blockers alone cannot be regarded as satisfactory long-term treatment and that mechani ... | 2008 | 2581421 |
the effects of subdiabetogenic streptozotocin doses on rat beta cell volume and functions. | the influence of a single i.v. injection of 30 mg/kg streptozotocin (sz) into female wistar rats on plasma glucose, pancreatic insulin content, volume and function of the remaining beta-cells has been investigated. 14 days after sz treatment most animals remained normoglycemic; only about 15% showed permanent hyperglycemia. the pancreatic insulin content in normoglycemic rats was reduced to 30%, whereas in hyperglycemic rats only 6% of control values could be detected. the remaining beta-cell vo ... | 1985 | 2581562 |
[synthesis of oligosaccharide fragments of o-specific shigella flexneri polysaccharides. ii. synthesis of trisaccharide glc alpha1----3rha alpha1----2rha alpha1----ome and tetrasaccharide glcnac beta1----2(llc alpha1----3)rha alpha1----2rh alpha1----ome]. | methyl glycosides of the title linear trisaccharide and branched tetrasaccharide were synthesized by stepwise glycosylation. these oligosaccharides represent the fragments of o-antigenic polysaccharides of shigella flexneri serotypes 2b, 3a, 5b, and x. | 1985 | 2581587 |
inflammatory bowel disease. | the place of inflammatory bowel disorders in the spondarthritis matrix has been discussed and aetiopathological and clinicoradiological features of their individual arthropathies described. particular emphasis has been placed on the arthropathies of ulcerative colitis and crohn's disease, but a comment is also included on the much rarer condition, whipple's disease. the position of reactive arthritis resulting from enteric infection in relation to the spondarthritis concept is examined in the li ... | 1985 | 2581732 |
a new system to produce intraoperatively custom femoral prosthesis from measurements taken during the surgical procedure. | a system has been developed that allows the surgeon to match a prosthesis to any femoral cavity. the surgeon may choose how and where it will preferentially fit. the surgeon does not have to create a cavity to suit a premade prosthesis. the system is based on a novel technique for making a mold of the prepared femoral cavity. this is accurately and thoroughly measured using a laser. an implant is designed and manufactured while the operation is in progress using state-of-the-art computer and mac ... | 2008 | 2582680 |
[value of irrigation-suction drainage in the treatment of early infection of joint implants]. | the analysis of follow-up examinations on 77 patients at the endo-klinik who were treated with suction irrigation drainage for acute postoperative infection after joint replacement surgery during the last 12 years showed a success rate up to a maximum of 60%. the success of this treatment increased, the earlier and more thoroughly it was performed. only when the suction irrigation drainage is combined with radical excision of infected soft tissue this operation can save the implant and prolong i ... | 2008 | 2582888 |
location of the second steroid-binding site on the glucocorticoid receptor. | the ability of nonradioactive progesterone to accelerate the dissociation of tritiated dexamethasone from the agonist-binding site of the glucocorticoid receptor was used as a probe for the existence of a second antagonist steroid site. the goal was to evaluate if this second site was on the glucocorticoid receptor and, if so, on what region of that protein. the magnitude of acceleration of dissociation was assessed during purification of the receptor as well as with the untransformed (multimeri ... | 2008 | 2583055 |
multiple zones in the sequence of calreticulin (crp55, calregulin, hacbp), a major calcium binding er/sr protein. | the complete amino acid sequence of crp55, the major 55 kd calcium binding protein of the er lumen, was deduced from the murine cdna nucleotide sequence. this was completed using a novel application of pcr amplification. the mature 399 residue protein encoded is preceded by a 17 amino acid leader sequence and ends in the er signal sequence, kdel. the protein contains no calcium binding motifs of the ef hand type or of the form seen in calelectrin-related proteins. the major region of potential l ... | 2008 | 2583110 |
multiple zones in the sequence of calreticulin (crp55, calregulin, hacbp), a major calcium binding er/sr protein. | the complete amino acid sequence of crp55, the major 55 kd calcium binding protein of the er lumen, was deduced from the murine cdna nucleotide sequence. this was completed using a novel application of pcr amplification. the mature 399 residue protein encoded is preceded by a 17 amino acid leader sequence and ends in the er signal sequence, kdel. the protein contains no calcium binding motifs of the ef hand type or of the form seen in calelectrin-related proteins. the major region of potential l ... | 2008 | 2583110 |
chronic colitis after aeromonas infection. | 1989 | 2583575 | |
what do you mean? | 2008 | 2583581 | |
some trematodes of freshwater fishes from north vietnam with a list of recorded endohelminths by fish hosts. | the present paper comprises a systematic survey of trematodes collected from 12 species of freshwater fishes from north vietnam (the red river near hanoi). altogether 16 trematode species (14 adults and 2 juvenile forms) have been recorded. these include: amurotrema dombrowskajae, platycladorchis microacetabularis, p. macroacetabularis, neocladorchis multilobularis, carassotrema koreanum, azygia hwangtsiyui, phyllodistomum clariasi, phyllodistomum sp., orientocreadium batrachoides, masenia colla ... | 1989 | 2583614 |
is transpiration an important mechanism for release of 222rn to the atmosphere? | 2008 | 2584022 | |
heme regulates expression of phycobiliprotein photogenes in the unicellular rhodophyte, cyanidium caldarium. | allophycocyanin and phycocyanin in the red alga (cyanidium caldarium) are chloroplast-encoded, light-harvesting accessory pigments composed of alpha and beta subunit polypeptides (17-19 kda) to which 1 or more residues of the heme-derived bile pigment chromophore phycocyanobilin are attached by cysteinyl thioether linkages (offner, g.d., and troxler, r.f. (1983) j. biol. chem. 258, 9931-9940). western blot experiments utilizing phycobiliprotein antisera revealed that immunoreactive allophycocyan ... | 2008 | 2584231 |
[a study of bronchial sensitivity and bronchial reactivity using astograph and transcutaneous oxygen tension in asthmatic children. the problems of simultaneous measurement]. | bronchial sensitivity and reactivity in 60 patients with bronchial asthma was measured using the astograph and simultaneous transcutaneous oxygen tension [ptco2]. in spite of increasing respiratory resistance, there were some cases in which ptco2 did not show remarkable decrease. the ptco2 percentage was defined as (basal value of ptco2 - bottom value of ptco2)/(basal value of ptco2). the correlation between ptco2% and the basal value of ptco2 was relatively high (r = 0.42, n = 58, p less than 0 ... | 2008 | 2584366 |
route of delivery of phenylalanine influences its effect on short-term food intake in adult male rats. | the effect of phenylalanine (phe) on plasma and brain phe and tyrosine (tyr) levels and on short-term food intake in male rats was measured after intragastric (i.g.), subcutaneous (s.c.) and intraperitoneal (i.p.) administration. compared to equimolar alanine (ala), which served as the control, phe significantly suppressed feeding at a dose of 90 mg/kg body wt when given i.p., but doses up to 720 mg/kg body wt had no effect when given i.g. or s.c. the high doses of phe given by the i.g. or s.c. ... | 1989 | 2585142 |
expression and desensitisation of a2 purinoceptors on cultured bovine aortic endothelial cells. | purine nucleotides and their metabolites are important mediators of vascular tone. adenosine promotes relaxation of vascular smooth muscle, acting on the a2 subclass of purinoceptors. there is some evidence that these receptors are also present on vascular endothelial cells. we have therefore examined cultured aortic endothelial cells for adenosine (a2) sensitivity. bovine aortic endothelial cells (ag4762) were obtained from the institute of aging cell repository (usa), and cultured in monolayer ... | 1989 | 2590913 |
recovery of proteins and peptides with nanogram loads on non-porous packings. | 1989 | 2592499 | |
pseudocyesis and depression. etiological and treatment considerations. | pseudocysesis, or false pregnancy, is generally classified as a conversion symptom and is usually treated as such with little success. depression, however, is a commonly associated phenomenon and is typically neglected in the formulation and treatment of this disorder. this report presents a case study in which the patient was referred for evaluation of pseudocyetic symptoms, but depression was judged to be the underlying problem. antidepressant therapy was instituted and found to be effective i ... | 2008 | 2592850 |
model predicting survival in stage i melanoma based on tumor progression. | we used the lesional steps in tumor progression and multivariable logistic regression to develop a prognostic model for primary, clinical stage i cutaneous melanoma. this model is 89% accurate in predicting survival. using histologic criteria, we assigned melanomas to tumor progression steps by ascertaining their particular growth phase. these phases were the in situ and invasive radial growth phase and the vertical growth phase (the focal formation of a dermal tumor nodule or dermal tumor plaqu ... | 2008 | 2593166 |
causes of death and the histopathologic findings in fatal shigellosis. | thirty-seven children (median age, 2 years) with shigellosis in bangladesh were subjected to postmortem examination to determine causes of death and the spectrum of intestinal histopathology. infecting species were: shigella dysenteriae 1, 7 cases; s. dysenteriae 2, 2 cases; shigella flexneri, 23 cases; shigella boydii, 4 cases; and mixed infection with shigella boydii and shigella sonnei, 1 case. complicating conditions detected before death included malnutrition in 25 cases, pneumonia in 11 ca ... | 1989 | 2594452 |
thoracic epidurals and general anaesthesia. | 2008 | 2596662 | |
[a case of advanced bladder cancer successfully treated with intraarterial chemotherapy]. | a 79-year-old japanese male came to our hospital with complaints of protraction and macroscopic total hematuria. the medical imaging methods revealed a large papillary tumor in the left lateral wall of the bladder with the staging of t3n0m0. the pathological diagnosis was transitional cell carcinoma, g3. he received intraarterial chemotherapy with cddp, adm and mtx, which was called ia-mac regimen. after two ia-mac, no medical imaging method could reveal the tumor. the biopsied specimen, which w ... | 2008 | 2596862 |
cadmium and lead accumulation by goldfish exposed to aqueous refuse incinerator fly ash leachate. | 2008 | 2597788 | |
calcaneal gait in spastic diplegia after heel cord lengthening: a study with gait analysis. | calcaneal gait or deformity can be a significant complication after heel cord lengthening. after heel cord lengthening, 20 children with spastic diplegia were evaluated by gait analysis to define calcaneal gait objectively and describe associated morbidity. mean age was 5 years 2 months (range 2 years 7 months to 8 years 2 months), and mean length of follow-up was 5 years 8 months (range 1 years 1 month 11 year 3 months). calcaneal gait was defined as dorsiflexion 1 sd beyond the mean in the sag ... | 2008 | 2600179 |
training for medical and biological illustration. | this paper will discuss the results of a study undertaken in 1986/7 into the education and training of medical artists and designers. it will attempt to identify the skills, knowledge and attitudes which are necessary and desirable for professional practice in the area. | 2008 | 2600354 |
forearm and wrist radiology--part i. | the emergency physician must be well versed in diagnosing forearm and wrist injuries. although many of these injuries are readily apparent, others require more sophistication to appreciate. careful attention to radiographic findings given the assistance of a well-directed history and physical examination is imperative. both the more common and the more subtle injuries are discussed. | 2008 | 2600399 |
[a case of turner's syndrome with ulcerative colitis]. | 2006 | 2600511 | |
differential blocking effects of atropine and gallamine on negative chronotropic and dromotropic responses to vagus stimulation in anesthetized dogs. | the negative dromotropic response to cervical vagus stimulation was inhibited less than the negative chronotropic response to cervical vagus stimulation by the same dose of atropine in neurally decentralized, anesthetized dogs. atropine and gallamine bind different muscarinic binding sites. we thus investigated the blocking effects of atropine and gallamine on the negative chronotropic and dromotropic responses to stimulation of the vagus nerves. we stimulated the intracardiac vagus nerves to th ... | 1989 | 2600814 |
rheumatoid synovial fluid reconstitutes the b-cell defect in cba/n mice. | synovial fluid from patients with rheumatoid arthritis (ra-sf) contains a biological activity which can replace t cells for activation of antibody secretion in human blood lymphoid cells and which can also induce the selective differentiation of igg2b-secreting cells in lipopolysaccharide (lps)-pre-activated mouse spleen cells. the b-cell activity of this factor was studied in cba/n mice which have an x-linked b-cell immunodeficiency which manifests itself as a defective humoral response to cert ... | 1989 | 2602914 |
[the role of morphologic studies in the diagnosis of malignant neoplasms]. | 2008 | 2603039 | |
maxillofacial prosthetics: unmasking the phantoms of everyday life. | 2008 | 2605767 | |
cardiopulmonary baroreflex control of brachial artery diameter in sustained essential hypertension. | an exaggerated reflex response of forearm resistance vessels following stimulation of cardiac mechanoreceptors has been observed in human hypertension. in the present study we analyze the possibility that such an increased response also involves the large brachial artery. for that purpose, the influence of leg elevation in subjects in a supine position on brachial artery diameter and blood flow velocity was studied in 12 healthy, normal males and 17 males of the same age with sustained essential ... | 1989 | 2607141 |
signal structure of the cis-acting element recognized by virg protein, a positive regulator in agrobacterium. | virg protein is known to be the positive regulator for vir genes of ri and ti plasmids in agrobacterium. to investigate the cis-acting element recognized by virg, we have determined the transcriptional start points of the vir genes on ri plasmid (pria4b). from the analysis of the upstream sequences, it has been found that the sequences generally similar to 5'tg(a/t)aa(c/t)3' appear in phase with an 11-base pair interval, and that the -35 and -10 regions of the promoters are located nearly in the ... | 1989 | 2608465 |
mandatory aids testing: factors influencing public opinion. | a survey of 341 persons, 82% of whom were university students whose median age was 27.0 yr., was conducted to investigate the relationship between their attitudes regarding mandatory aids testing for various groups, attitudes toward the disease, sexual orientation and behavior, and attitudes toward homosexuals. homosexual and bisexual respondents were less supportive of mandatory testing for anyone than were heterosexual respondents. greater homophobia and attitudes in favor of legal sanctions a ... | 2008 | 2608844 |
symptoms associated with diarrhoeal illness at san lazaro hospital, manila in 1983 and 1984. | the clinical features associated with various agents of diarrhoeal disease were studied using 2,836 patients admitted to san lazaro hospital, manila. three general patient groups were considered including single pathogen isolations, "multiple pathogen" isolations, and "no pathogen" isolations. in general, symptoms of diarrhoeal illness were found to be non-specific. however, shigella flexneri. vibrio parahemolyticus, and rotavirus were significantly associated with a number of prominent symptoms ... | 1989 | 2609210 |
three dimensional observations of the palisade-shaped nerve endings of normal hair of rat's snout. | the nerve endings of normal hair of the rat's snout, partially digested with trypsin and hydrochloric acid, were studied by scanning electron microscopy. each lanceolate structure measured ca. 10 microns in length and was arranged around the hair follicle. these palisade-shaped nerve endings were situated almost beneath the sebaceous glands, ran upward, parallel to the axis of the hair follicle, and terminated in pointed shape. 2 kinds of cells, teloglia cell type i showing flat profile, and tel ... | 1989 | 2610376 |
[the course of varicose disease. parallel retrospective study of 2 ethnic groups (catania-basel)]. | authors presents a retrospective study with two different ethnic groups, one of them from catania and the other from basilea, with varicose veins and subjected to a saphenectomy. they studies the following parameters: age at the entrance, and when varicose veins appeared; correlation between varix appearance date and subjective symptomatology; and rapport between varix complications and its duration. the possible incidence of "ambiental factor" and contrasts between the two groups are considered ... | 2008 | 2610399 |
studies on acute toxic effects to keratinocytes induced by hematoporphyrin derivatives and laser light. | human epidermal keratinocytes were grown in culture and the uptake of hematoporphyrin derivatives (hpds) used in photodynamic therapy was estimated. keratinocytes loaded with hpds were irradiated with laser light of 632 nm generated by a helium-neon laser and cell toxicity was determined by the trypan blue exclusion test and the measurement of enzyme release. with increasing intracellular concentration of hpds and with increasing intensity of the laser light, an increasing number of cells took u ... | 1989 | 2610520 |
children's responses to different forms of expression of anger between adults. | anger is not a homogeneous stimulus, but can vary on a variety of dimensions and domains. this study examined children's responses to anger as a function of: (a) the mode of expression of anger (nonverbal, verbal, verbal-physical), and (b) whether or not anger between others was resolved. children were presented with videotaped segments of angry and friendly interactions and asked questions concerning their responses. all angry interactions, including non-verbal anger, were perceived as negative ... | 2008 | 2612248 |
children's responses to different forms of expression of anger between adults. | anger is not a homogeneous stimulus, but can vary on a variety of dimensions and domains. this study examined children's responses to anger as a function of: (a) the mode of expression of anger (nonverbal, verbal, verbal-physical), and (b) whether or not anger between others was resolved. children were presented with videotaped segments of angry and friendly interactions and asked questions concerning their responses. all angry interactions, including non-verbal anger, were perceived as negative ... | 2008 | 2612248 |
[transplants. reflections on the role of the periodontal ligament and resorption risk]. | 2008 | 2612260 | |
[transplants. reflections on the role of the periodontal ligament and resorption risk]. | 2008 | 2612260 | |
[recurrence after intestinal resection for crohn's disease]. | although recurrence is one of the major problems in the surgical management of a patient with crohn disease, the factors that influence recurrence rate remain controversial. to elucidate some of this controversy, the records of a consecutive series of 100 patients, who underwent resectional surgery for crohn's disease, were analyzed to evaluate the effect of several clinical and histologic features on the recurrence rate. in this study, recurrence was defined as clinical and or laboratory findin ... | 2008 | 2612273 |
[recurrence after intestinal resection for crohn's disease]. | although recurrence is one of the major problems in the surgical management of a patient with crohn disease, the factors that influence recurrence rate remain controversial. to elucidate some of this controversy, the records of a consecutive series of 100 patients, who underwent resectional surgery for crohn's disease, were analyzed to evaluate the effect of several clinical and histologic features on the recurrence rate. in this study, recurrence was defined as clinical and or laboratory findin ... | 2008 | 2612273 |
composition and chromosomal localization of cetacean highly repetitive dna with special reference to the blue whale, balaenoptera musculus. | three highly repetitive dna components--the common cetacean component, the heavy (gc-rich) satellite and the light (at-rich) satellite--were were studied in the blue whale. consensus sequences of the common component and the heavy satellite were determined on the basis of three repeats of the common component and eight repeats of the heavy satellite. the tandemly organized common cetacean component, which comprises a large portion of all cetacean--both odontocete (toothed whale) and mysticete (w ... | 2008 | 2612291 |
composition and chromosomal localization of cetacean highly repetitive dna with special reference to the blue whale, balaenoptera musculus. | three highly repetitive dna components--the common cetacean component, the heavy (gc-rich) satellite and the light (at-rich) satellite--were were studied in the blue whale. consensus sequences of the common component and the heavy satellite were determined on the basis of three repeats of the common component and eight repeats of the heavy satellite. the tandemly organized common cetacean component, which comprises a large portion of all cetacean--both odontocete (toothed whale) and mysticete (w ... | 2008 | 2612291 |
ecotoxicological characterization of industrial wastewater--sulfite pulp mill with bleaching. | different process wastewaters from a sulfite pulp mill with bleaching were characterized by chemical analysis and toxicity tests. the amount of adsorbable organically bound halogen (aox) from the bleachery was 3.6 kg per ton pulp. the extractable organically bound chlorine was 15% of aox. some identified organochlorine compounds in the effluent could be traced in the receiving water. effluents from the chlorination and alkaline extraction stages and the condensate were the main contributors to t ... | 1989 | 2612424 |
ecotoxicological characterization of industrial wastewater--sulfite pulp mill with bleaching. | different process wastewaters from a sulfite pulp mill with bleaching were characterized by chemical analysis and toxicity tests. the amount of adsorbable organically bound halogen (aox) from the bleachery was 3.6 kg per ton pulp. the extractable organically bound chlorine was 15% of aox. some identified organochlorine compounds in the effluent could be traced in the receiving water. effluents from the chlorination and alkaline extraction stages and the condensate were the main contributors to t ... | 1989 | 2612424 |
effects of postnatal dexamethasone treatment on development of alveoli in adult rats. | we compared the effects of dexamethasone given to rats from age 4 to 14 days, on alveolar development at age 99 days. judged by similar nose-to-tail length and body weight, somatic growth was not altered by dexamethasone treatment. lung volumes in both air- and saline-filled lungs and mean chord length (lm) were increased, whereas alveolar surface area (sa) and surface-to-volume ratio (s/v) were diminished in dexamethasone-treated adult rats. these changes were associated with a significant redu ... | 1989 | 2612450 |
effects of postnatal dexamethasone treatment on development of alveoli in adult rats. | we compared the effects of dexamethasone given to rats from age 4 to 14 days, on alveolar development at age 99 days. judged by similar nose-to-tail length and body weight, somatic growth was not altered by dexamethasone treatment. lung volumes in both air- and saline-filled lungs and mean chord length (lm) were increased, whereas alveolar surface area (sa) and surface-to-volume ratio (s/v) were diminished in dexamethasone-treated adult rats. these changes were associated with a significant redu ... | 1989 | 2612450 |
pathophysiological variations in the rat liver plasma membrane serine proteinase activity. | the effects of fasting, diabetes, cholestasis, two-third hepatectomy and adrenalectomy on the rat liver plasma membrane serine proteinase activity were studied. our results show a significant decrease of the enzyme activity during fasting (-50%), during experimental diabetes (-50%), in regenerating liver after partial hepatectomy (-70%) and after extrahepatic cholestasis (-70%). no modifications are noted when the rats are bilaterally adrenalectomized. these findings suggest that the enzyme acti ... | 1989 | 2612451 |
pathophysiological variations in the rat liver plasma membrane serine proteinase activity. | the effects of fasting, diabetes, cholestasis, two-third hepatectomy and adrenalectomy on the rat liver plasma membrane serine proteinase activity were studied. our results show a significant decrease of the enzyme activity during fasting (-50%), during experimental diabetes (-50%), in regenerating liver after partial hepatectomy (-70%) and after extrahepatic cholestasis (-70%). no modifications are noted when the rats are bilaterally adrenalectomized. these findings suggest that the enzyme acti ... | 1989 | 2612451 |
results of pancreatoduodenectomy for carcinoma of the head of the pancreas. | seventy-eight patients underwent either pancreatoduodenectomy (88%) or total pancreatectomy (12%) for carcinoma of the head of the pancreas. the operative mortality decreased from 27% in 1968-1977 to 3% in 1978-1987. there was no operative mortality during the last 5-year period 1983-1987. mortality (9% vs 7%) and morbidity (57% vs 42%) were similar in patients aged greater than or equal to 70 and less than 70 years. the pylorus-preserving technique did not increase mortality or operative blood ... | 2009 | 2613164 |
[clinical study of osteoporosis]. | 2008 | 2614196 | |
[a case of acute benzalkonium chloride intoxication]. | 2008 | 2614210 | |
membrane current responses of skate photoreceptors. | light-evoked membrane currents were recorded with suction electrodes from the outer segments of individual photoreceptors enzymatically dissociated from the skate retina. the intensity-response relation of dark-adapted cells closely followed a michaelis function for which a half-saturating response was elicited by a flash intensity that produced about 36 photoisomerizations. dim-light responses, as well as the early rising phase of the responses to a wide range of flash intensities, could be des ... | 2008 | 2614369 |
submission of nucleotide sequence data to genbank. | 2008 | 2614392 | |
characterization of excretory-secretory proteins synthesized in vitro by schistosoma mansoni primary sporocysts. | excretory-secretory (e-s) products released by larval schistosomes have been implicated in the interference of host snail defense systems. because of the potentially important role that e-s products play in the parasite-host relationship, total and newly synthesized e-s proteins from in vitro-cultured schistosoma mansoni primary sporocysts were characterized using incorporation of [35s]methionine followed by sodium dodecylsulfate polyacrylamide gel electrophoresis (sds-page) and fluorography. to ... | 1989 | 2614597 |
aluminum induced anemia: pathogenesis and treatment in patients on chronic hemodialysis. | the baseline hematologic status of 27 patients with modest degrees of aluminum overload was examined. in addition, hematologic data were evaluated in 19 of these patients during and after treatment with dfo. although neither severe anemia nor microcytosis was observed pretreatment, there was a significant correlation between hemoglobin level and degree of aluminum burden as determined by bone surface aluminum staining (r = -0.58; p less than 0.007). following treatment with dfo, hemoglobin conce ... | 2008 | 2615192 |
[nursing career development program by private industry--from job management to career management]. | 2009 | 2615507 | |
indomethacin blocks the anorexic action of interleukin-1. | it has been reported recently that the central nervous system actions of interleukin-1 are mediated by the prostaglandin system in the brain. the present study was therefore performed in order to examine the hypothesis that indomethacin, an inhibitor of prostaglandin biosynthesis, might alleviate the interleukin-1-induced suppression of food intake in rats. the i.p. injection of interleukin-1 (2 micrograms/rat) resulted in a significant decrease in food intake. the pre-injection of indomethacin ... | 1989 | 2620696 |
indomethacin blocks the anorexic action of interleukin-1. | it has been reported recently that the central nervous system actions of interleukin-1 are mediated by the prostaglandin system in the brain. the present study was therefore performed in order to examine the hypothesis that indomethacin, an inhibitor of prostaglandin biosynthesis, might alleviate the interleukin-1-induced suppression of food intake in rats. the i.p. injection of interleukin-1 (2 micrograms/rat) resulted in a significant decrease in food intake. the pre-injection of indomethacin ... | 1989 | 2620696 |
[meta-analysis. a systematic approach to the synthesis of knowledge]. | 2008 | 2620806 | |
[meta-analysis. a systematic approach to the synthesis of knowledge]. | 2008 | 2620806 | |
synaptonemal complex analysis of hybrid cattle. i. pachytene substaging and the normal full bloods. | meiotic chromosome pairing abnormalities in full-blood and hybrid bos taurus and b. indicus cattle have been surveyed by electron microscopy of pachytene synaptonemal complex spreads. in this paper the full-blood spreads are described in detail, including the use of xy and nucleolar morphology and other measured parameters for pachytene substaging. pairing abnormalities were observed in up to 9% of the full-blood spreads. most of these pairing abnormalities (83%) occurred in early-pachytene spre ... | 1989 | 2620818 |
synaptonemal complex analysis of hybrid cattle. i. pachytene substaging and the normal full bloods. | meiotic chromosome pairing abnormalities in full-blood and hybrid bos taurus and b. indicus cattle have been surveyed by electron microscopy of pachytene synaptonemal complex spreads. in this paper the full-blood spreads are described in detail, including the use of xy and nucleolar morphology and other measured parameters for pachytene substaging. pairing abnormalities were observed in up to 9% of the full-blood spreads. most of these pairing abnormalities (83%) occurred in early-pachytene spre ... | 1989 | 2620818 |
occupational health and safety and general practitioners. | 2009 | 2621354 | |
involvement of the legs in idiopathic striae distensae--a case report. | a case of idiopathic striae distensae (isd) is presented. the patient was a healthy young adult with no history of weight lifting, use of systemic or local corticosteroids, infections or trauma. horizontally disposed striae were located on the abdomen, back and legs. to the best of our knowledge this is the first report case of isd where idiopathic striae were present below the knees. | 2008 | 2625361 |
[experimental and clinical studies on the exclusion and bypassing operation for abdominal aortic and iliac artery aneurysms]. | for the purpose of simplifying operative techniques and decreasing operative risks, we evaluated excusion and bypassing operation for infrarenal abdominal aortic and iliac artery aneurysm (aaa) both experimentally and clinically. this method includes dissection and closure of proximal stump of the aneurysm and anatomical bypass technique in principle. in the experiments, the ratio of internal pressure of the excluded aorta (e.ao) to systemic blood pressure (e.p.i.) was 0.62 +/- 0.03 (n = 7, mean ... | 1989 | 2626156 |
[experimental and clinical studies on the exclusion and bypassing operation for abdominal aortic and iliac artery aneurysms]. | for the purpose of simplifying operative techniques and decreasing operative risks, we evaluated excusion and bypassing operation for infrarenal abdominal aortic and iliac artery aneurysm (aaa) both experimentally and clinically. this method includes dissection and closure of proximal stump of the aneurysm and anatomical bypass technique in principle. in the experiments, the ratio of internal pressure of the excluded aorta (e.ao) to systemic blood pressure (e.p.i.) was 0.62 +/- 0.03 (n = 7, mean ... | 1989 | 2626156 |
[primary and secondary neoplasms of the salivary glands in the province of trieste (1977-1986). histopathological review and epidemiological picture of 151 cases]. | the authors carried out a histopathological and epidemiological study on 151 cases of primary and secondary neoplasms of the salivary glands. the parotid gland was involved in 117 cases (78.5%). the tumours were malignant in 20% (30 cases) of the lesions. the most common neoplasms were pleomorphic adenoma (74 cases) and adenolymphoma (35 cases). the occurrence of the latter were, for both sexes, directly correlated to the age of the subjects. the malignant neoplasms were also in direct relation ... | 2009 | 2626276 |