Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| gene promoter methylation and protein expression of brms1 in uterine cervix in relation to high-risk human papilloma virus infection and cancer. | cervical cancer is strongly related to certain high-risk types of human papilloma virus infection. breast cancer metastasis suppressor 1 (brms1) is a tumor suppressor gene, its expression being regulated by dna promoter methylation in several types of cancers. this study aims to evaluate the methylation status of brms1 promoter in relation to high-risk types of human papilloma virus infection and the development of pre-cancerous lesions and describe the pattern of brms1 protein expression in nor ... | 2017 | 28381193 |
| unique dna methylation signature in hpv-positive head and neck squamous cell carcinomas. | head and neck squamous cell carcinomas (hnsccs) represent a heterogeneous group of cancers for which human papilloma virus (hpv) infection is an emerging risk factor. previous studies showed promoter hypermethylation in hpv(+) oropharyngeal cancers, but only few consistent target genes have been so far described, and the evidence of a functional impact on gene expression is still limited. | 2017 | 28381277 |
| decline in hospitalization for genital warts in the veneto region after an hpv vaccination program: an observational study. | human papillomavirus (hpv) is one of the most common sexually transmitted pathogens. this observational study was conducted to estimate the trend of hospitalization for genital warts (gws) in the veneto region (italy) from 2004 to 2015. | 2017 | 28381294 |
| major clinical research advances in gynecologic cancer in 2016: 10-year special edition. | in 2016, 13 topics were selected as major research advances in gynecologic oncology. for ovarian cancer, study results supporting previous ones regarding surgical preventive strategies were reported. there were several targeted agents that showed comparable responses in phase iii trials, including niraparib, cediranib, and nintedanib. on the contrary to our expectations, dose-dense weekly chemotherapy regimen failed to prove superior survival outcomes compared with conventional triweekly regimen ... | 2017 | 28382802 |
| genetic mutation and exosome signature of human papilloma virus associated oropharyngeal cancer. | human papilloma virus-16 (hpv-16) associated oropharyngeal cancer (hpvopc) is increasing alarmingly in the united states. we performed whole genome sequencing of a 44 year old, male hpvopc subject diagnosed with moderately differentiated tonsillar carcinoma. we identified new somatic mutation in muc16 (a.k.a. ca-125), muc12, muc4, muc6, muc2, sirpa, hla-drb1, hla-a and hla-b molecules. increased protein expression of muc16, sirpa and decreased expression of hla-drb1 was further demonstrated in t ... | 2017 | 28383029 |
| using a patient navigator to improve postpartum care in an urban women's health clinic. | to estimate whether postpartum visit attendance was improved in women exposed to a postpartum patient navigation program compared with those who received care immediately before the program's initiation and to assess whether other postpartum health behaviors improved during the intervention period. | 2017 | 28383374 |
| immunisation coverage annual report, 2014. | this 8th annual immunisation coverage report shows data for 2014 derived from the australian childhood immunisation register and the national human papillomavirus vaccination program register. this report includes coverage data for 'fully immunised' and by individual vaccines at standard age milestones and timeliness of receipt at earlier ages according to indigenous status. overall, 'fully immunised' coverage has been mostly stable at the 12- and 24-month age milestones since late 2003, but at ... | 2017 | 28385140 |
| generalized verrucosis and abnormal t cell activation due to homozygous taok2 mutation. | generalized verrucosis (gv) is a chronic and progressive cutaneous human papillomavirus (hpv) infection resulting in multiple warts and associated with acquired or genetic immune defects. we identified a consanguineous arab family manifesting gv and recurrent bacterial and viral infections, in association with inflammatory bowel disease (ibd). | 2017 | 28385331 |
| hpv-transgenic mouse models: tools for studying the cancer-associated immune response. | for decades, research on the pathogenesis of papillomavirus-induced lesions, particularly of human papillomavirus (hpv) has relied on the use of animal models. among these, hpv-transgenic mice are some of the most frequently employed. after some initial unsuccessful attempts, researchers have succeeded in targeting the expression of one or more hpv-16 oncogenes to squamous epithelia, closely mimicking the lesions observed in cancer patients. the present review describes the relevance and usefuln ... | 2017 | 28385491 |
| single-organ vasculitis of the cervix accompanying human papillomavirus infection. | single-organ vasculitis (sov) has rarely been reported to involve the female genital tract but mostly the uterine cervix. a 39-year-old woman was diagnosed to have a high-grade cervical intraepithelial lesion and was treated by large loop excision of the transformation zone. histopathological evaluation of the excised specimen confirmed the diagnosis of cervical intraepithelial neoplasia grade iii accompanied by human papillomavirus infection. the excised second specimen showed the evidence of v ... | 2016 | 28386466 |
| multifocal epithelial hyperplasia. | multifocal epithelial hyperplasia is a rare disease associated with human papilloma virus types 13 and 32. diagnosis is based on clinical and histopathological findings, and most lesions are asymptomatic and regress spontaneously with time. the purpose of this paper is to describe a five-year-old girl who presented with multiple intraoral lesions on the buccal mucosa and tongue, which regressed spontaneously in 15 months. | 2017 | 28387191 |
| hpv-negative penile squamous cell carcinoma: disruptive mutations in the tp53 gene are common. | the majority of penile squamous cell carcinomas is caused by transforming human papilloma virus (hpv) infection. the etiology of hpv-negative cancers is unclear, but tp53 mutations have been implicated. archival tissues of 108 invasive squamous cell carcinoma from a single pathology institution in a low-incidence area were analyzed for hpv-dna and p16(ink4a) overexpression and for tp53 mutations by ion torrent next-generation sequencing. library preparation failed in 32/108 squamous cell carcino ... | 2017 | 28387325 |
| in silico analysis of l1/l2 sequences of human papillomaviruses: implication for universal vaccine design. | the aim of this study was to design a multiepitope universal vaccine for major human papillomavirus (hpv) structural proteins, l1/l2, by bioinformatics models. for this purpose, we predicted the most probable immunogenic epitopes of l1 and l2 from common high-risk hpv 16, 18, 31, and 45 beside high prevalent type 6 and 11 based on bcpreds defaulted model, while solvent accessibility of structure was extrapolated. the three-dimensional molecular model of l1 protein was constructed by swiss model ... | 2017 | 28388355 |
| retrospective study of the influence of hpv persistence on outcomes among women with high-risk hpv infections and negative cytology. | to evaluate the outcomes of women diagnosed with high-risk hpv without cytology evidence of cervical dysplasia. | 2017 | 28388819 |
| enhanced efficacy with reduced toxicity of chemotherapy drug 5-fluorouracil by synergistic treatment with abnormal savda munziq from uyghur medicine. | abnormal savda munziq (asmq) is a traditional prescription in uyghur medicine, and its treatment of complex diseases such as tumors and asthma has been proven to be effective in uyghur medical clinical practice. the efficacy-enhancing and toxicity-reducing properties of asmq were studied on mice with transplanted cervical cancer (u27) tumors, which were treated with 5-fluorouracil (5-fu) in this work. | 2017 | 28388901 |
| identification and characterization of enhancer agonist human cytotoxic t-cell epitopes of the human papillomavirus type 16 (hpv16) e6/e7. | human papillomavirus (hpv) is associated with the etiology of cervical carcinoma, head and neck squamous cell carcinoma, and several other cancer types. vaccines directed against hpv virus-like particles and coat proteins have been extremely successful in the prevention of cervical cancer through the activation of host hpv-specific antibody responses; however, hpv-associated cancers remain a major public health problem. the development of a therapeutic vaccine will require the generation of t-ce ... | 2017 | 28389098 |
| genotypic diversity of anogenital human papillomavirus in women attending cervical cancer screening in harare, zimbabwe. | although anogenital cancers have been on a gradual rise in developing countries in the past few decades, they have been understudied. | 2017 | 28390142 |
| concordance of hpv-dna in cervical dysplasia or genital warts in women and their monogamous long-term male partners. | transmission of human papillomavirus (hpv) is a premise for development of cervical dysplasia and genital warts. this cross-sectional study assesses concordance of hpv types present in genital warts or cervical dysplasia in women and genital infection of their monogamous male partners in conjunction with seroprevalence of hpv-6,-11,-16 and -18 antibodies. blood was taken from both women and men, as well a smear of the urogenital area of men. hpv dna detection in women was done in fixed paraffin ... | 2017 | 28390162 |
| evaluation of the performance of human papillomavirus testing in paired urine and clinician-collected cervical samples among women aged over 30 years in bhutan. | urine sampling may offer a less invasive solution than cervical sampling to test for human papillomavirus (hpv) for hpv vaccine impact monitoring. | 2017 | 28390433 |
| reproductive health screening in women with autoimmune diseases. | although the female predominance of autoimmune diseases is not completely understood, sex hormones are thought to play a role. attention to lifelong reproductive health is especially important for women with autoimmune disorders. many of these women require long-term immunosuppressive therapy that may affect their ability to clear infections, including viruses, and may alter natural tumor surveillance mechanisms. as a result, women with autoimmune diseases may have different risks for common rep ... | 2017 | 28390560 |
| evolving disparities in the epidemiology of oral cavity and oropharyngeal cancers. | incidence rates of head and neck cancers (hnc) associated with human papillomavirus (hpva) infection are increasing while non-hpv-associated (non-hpva) hnc cancer rates are decreasing. as nearly all sexually active individuals will acquire an hpv infection, it is important to understand epidemiologic trends of hncs associated with this sexually transmitted disease. we analyzed seer 9 (1973-2012) and 18 data (2000-2012) for hpva hncs (oropharynx area; op) and non-hpva (oral cavity area; oc). inci ... | 2017 | 28391376 |
| hpv testing in first-void urine provides sensitivity for cin2+ detection comparable to a physician-taken smear or brush-based self-sample: cross-sectional data from a triage population. | to compare sensitivity of high-risk hpv (hrhpv) and genotype detection in self-collected morning (u1) and later (u2) urine samples, brush-based self-samples (ss) and physician-taken smears (pts) for detecting cin2+ in a colposcopic referral population. | 2017 | 28391609 |