Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [relationship between pd-1 expression on peripheral t lymphcytes and hbeag seroconversion after entecavir treatment in chronic hepatitis b patients.] | to observe longitudinally the expression of programmed death 1(pd-1) on peripheral blood t cells in chronic hepatitis b patients underwent antiviral treatment with entecavir (etv) and to explore the relationship between pd-1 expression and hbeag seroconversion. twenty hbeag positive patients underwent antiviral treatment with etv were followed up for 51 weeks. 14 patients remained hbeag positive and 6 patients achieved hbeag seroconversion. peripheral blood was collected at six time points: t0: ... | 2011 | 21492509 |
| oncologic outcomes after supracricoid partial laryngectomy. | objective. to review the oncologic outcomes of a series of supracricoid partial laryngectomy. design. case series with chart review. setting. la paz university hospital, madrid, spain. patients. forty-one patients with glottic or supraglottic squamous cell carcinoma who underwent supracricoid partial laryngectomy between 1998 and 2008 at the authors' institution. main outcome measure. local control rate, specific-disease survival rate, and overall survival rate. results. all patients were male, ... | 2011 | 21493316 |
| salvage laryngectomy after primary radiotherapy: what are prognostic factors for the development of pharyngocutaneous fistulae? | in this evidence based case report we addressed the clinical question: which factors predict the occurrence of a pharyngocutaneous fistula after total laryngectomy in patients that already were treated with radiotherapy for a squamous cell carcinoma of the larynx? we searched for relevant synonyms for the domain, being patients earlier treated with radiotherapy for a squamous cell carcinoma of the larynx and having a recurrence for which a salvage total laryngectomy is necessary, with the outcom ... | 2011 | 21493379 |
| disruptive effects of persistent organohalogen contaminants on thyroid function in white whales (delphinapterus leucas) from svalbard. | we analysed levels of 56 organohalogen contaminants (ohcs) including brominated flame retardants, polychlorinated biphenyls (pcbs), and organochlorine pesticides in the blubber of white (beluga) whales (delphinapterus leucas) from svalbard, norway (n=12; 6 adults [5 males and 1 female] and 6 subadults [4 males and 2 females]) collected in 1996-2001. we also measured circulating levels of thyroid hormones (ths) and thyroid stimulating hormone (tsh) in the whales. the results confirm that ohc leve ... | 2011 | 21497377 |
| salivary zinc finger protein 510 peptide as a novel biomarker for detection of oral squamous cell carcinoma in early stages. | oral squamous cell carcinoma (oscc) is one of the most frequent malignancies worldwide. early diagnosis can mean adequate treatment and increase survival. | 2011 | 21497587 |
| the new tumor, node, and metastasis staging system. | the seventh edition of the tumor, node, and metastasis (tnm) classification is based on the proposals of the staging project of the international association for the study of lung cancer (iaslc). the analyses of the iaslc international database of 81,015 patients diagnosed with lung cancer between 1990 and 2000 were used to validate the tnm descriptors. the changes include: the subclassification of t1 and t2 tumors into t1a (≤ 2 cm) and t1b (>2 and ≤ 3 cm), and t2a (>3 and ≤ 5 cm) and t2b (>5 an ... | 2011 | 21500123 |
| [effectiveness of transarticular approach in treating thoracic spinal stenosis of calcified ligament]. | to investigate the effectiveness of transarticular approach in treating thoracic spinal stenosis due to ossification of ligamentum flavum (olf) and ossification of posterior longitudinal ligament (opll) at the same level. | 2011 | 21500584 |
| thermostabilisation of an agonist-bound conformation of the human adenosine a(2a) receptor. | the adenosine a(2a) receptor (a(2a)r) is a g-protein-coupled receptor that plays a key role in transmembrane signalling mediated by the agonist adenosine. the structure of a(2a)r was determined recently in an antagonist-bound conformation, which was facilitated by the t4 lysozyme fusion in cytoplasmic loop 3 and the considerable stabilisation conferred on the receptor by the bound inverse agonist zm241385. unfortunately, the natural agonist adenosine does not sufficiently stabilise the receptor ... | 2011 | 21501622 |
| do children and adolescents with type 1 diabetes mellitus have a higher frequency of parietal cell antibodies than healthy controls? | parietal cell antibodies (pca) are markers of autoimmune gastritis (ag). ag can lead to hypergastrinemia and iron-deficiency anaemia (ida). compared to healthy controls, adults with type 1 diabetes mellitus (t1dm) show a higher prevalence of pca (1% vs 20%). the aim of the present study was to evaluate the frequency of pca in children and adolescents with t1dm compared to healthy controls and the clinical and biochemical markers. | 2011 | 21502826 |
| evaluation of the effect of l: -thyroxin therapy on endothelial functions in patients with subclinical hypothyroidism. | subclinical hypothyroidism (sh) is characterized by normal serum free t4 (ft4), free t3 (ft3) levels and increased serum thyroid-stimulating hormone (tsh) levels. endothelial dysfunction, which is an early step of atherosclerosis, has been reported in patients with subclinical hypothyroidism. the aim of this study is to evaluate endothelial functions and the effect of l: -thyroxin (l-t4) therapy on endothelial functions in sh. twenty-seven patients with sh and 22 healthy controls were evaluated ... | 2011 | 21505892 |
| t4-like genome organization of the escherichia coli o157:h7 lytic phage ar1. | we report the genome organization and analysis of the first completely sequenced t4-like phage ar1 of e. coli o157:h7. unlike most of the other sequenced phages of o157:h7 strain that belong to the temperate podoviridae and siphoviridae families, ar1 is a t4-like phage known to efficiently infect this pathogenic bacterial strain. the 167,435-bp ar1 genome is currently the largest among all the sequenced e. coli o157:h7 phages. it encodes a total of 281 potential orfs and ten putative trna genes. ... | 2011 | 21507986 |
| variation of the position of the aorta relative to a kyphotic thoracic spine: safety margin for pedicle screw placement in the adult japanese population. | abstract: study design: an analysis of computed tomography images of the spine in adult japanese patients.objective: to evaluate the variation of the position of the aorta relative to a spine with a thoracic kyphotic angle and to verify the safety margin for transpedicular screw fixation.summary of background data: recent studies have suggested that the aorta is positioned more laterally and posteriorly in patients with idiopathic scoliosis than in normal patients; however, variation of the posi ... | 2011 | 21508888 |
| nociceptive inputs transmission in huntington's disease: a study by laser evoked potentials. | the aim of the present study was to evaluate pain perception and evoked responses by laser stimuli (leps) in mild not demented huntington's disease (hd) patients. twenty-eight hd patients and 30 control subjects were selected. leps were obtained by four scalp electrodes, (fz, cz, referred to the nasion; t3, t4, referred to fz), stimulating the dorsum of both hands. all patients were also evaluated by somatosensory evoked potentials (seps) by median nerve stimulation. only 3 patients referred pai ... | 2011 | 21510231 |
| the effects of bromazepam over the temporo-parietal areas during the performance of a visuomotor task: a qeeg study. | this study investigated the effects of bromazepam on qeeg when 14 healthy subjects were asked to perform a visuomotor task (i.e., motor vehicle driving task). the subjects were exposed to two experimental conditions: the placebo (pl) and 6mg of bromazepam (br 6mg), following a randomized, double-blind design on different days. specifically, we observe absolute power extracted from qeeg data for theta band. we expected to see a decrease in absolute theta power in the temporal and parietal areas d ... | 2011 | 21511002 |
| mct8: from gene to disease and therapeutic approach. | thyroid hormone metabolism and action are largely intracellular processes that require transport of the hormone across the plasma membrane by different transporters. two of these, mct8 and mct10, are close members of the monocarboxylate transporter family. mct8 is expressed in a variety of tissues, including liver, kidney, thyroid and brain. the mct8 gene is located on the x chromosome, and mutations in mct8 result in severe psychomotor retardation and low serum t4 and high t3 levels in affected ... | 2011 | 21511238 |
| development of hepatocellular carcinomas in patients with absence of tumors on a prior ultrasound examination. | background: to evaluate hepatocellular carcinoma (hcc) that developed in patients with no evidence of a tumor during a prior ultrasound (us) performed within 1 year of the diagnosis. methods: we retrospectively analyzed data for 100 consecutive patients with liver cirrhosis who had undergone us within 1 year prior to hcc diagnosis and who showed no liver lesions on the previous us. size and t stage of hcc were assessed as well as whether patients met surgical criteria for liver transplantation a ... | 2011 | 21514759 |
| effect of a combined iodine and selenium supplementation on i and se status of cows and their calves. | iodine (i) and selenium (se) deficiencies are commonly reported in cattle, however, there are also studies regarding a very high iodine supply. the aim of the study was to determine the long-term effect of i and se supplementation on non-pregnant cows, pregnant cows and their calves. the hypothalamus pituitary axis was investigated (tsh, t4, t3 assays) during a trh challenge on non-pregnant cows. twenty-four cows, half of them pregnant, were assigned into 2 diet-groups, one group with a low i (0 ... | 2011 | 21514807 |
| [clinical analysis of malignant submandibular tumor]. | the 14 cases of malignant submandibular tumor whose treatment outcome we analyzed between 1989 and 2008 included 5 of adenoid cystic carcinoma, 3 of squamous cell carcinoma, 2 each of mucoepidermoid carcinoma, and carcinoma ex pleomorphic adenoma, and 1 each of carcinosarcoma and large-cell carcinoma. one subject was diagnosed with t1, 7 with t2, 4 with t3, and 2 with t4. lymph node involvement occurred in 5, -1 with n1 and 4 with n2. none had distant metastasis on the first visit. seven were tr ... | 2011 | 21516710 |
| in vitro fluorescence displacement investigation of thyroxine transport disruption by bisphenol a. | bisphenol a (bpa) is a chemical with high production volume and wide applications in many industries. although bpa is known as an endocrine disruptor, its toxic mechanisms have not been fully characterized. due to its structural similarity to thyroid hormones thyroxine (t4) and triiodothyronine (t3), one possible mechanism of bpa toxicity is disruption of hormone transport by competitive binding with the transport proteins. in this study, the binding interactions of bpa, t4, and t3 with three th ... | 2011 | 21517007 |
| neoadjuvant chemotherapy for locally advanced breast cancer in a malaysian tertiary hospital. | introduction: neoadjuvant chemotherapy for locally advanced breast cancer is given with the aim of shrinking the disease sufficiently for surgery. however, many clinical trials investigating neoadjuvant chemotherapy regimens were conducted for operable breast cancer. methods and materials: patients with t3-4, n2 m0 breast cancer diagnosed between january 2005 and december 2008 and who received at least one cycle of neoadjuvant chemotherapy were eligible for this study. thirty-four patients were ... | 2011 | 21517250 |
| a case of tsh-producing adenoma treated with octreotide in combination with thiamazole for the control of tsh and thyroid hormones after trans-sphenoidal neurosurgery. | while tsh-producing adenoma (tshoma) is rare, the diagnosis is often delayed because the clinical features are heterogeneous. the patient was a 69-year-old woman who had been referred to the yachiyo medical center in august 2008, because of dyspnea, loss of appetite, weight loss of 10 kg, and diarrhea that lasted 4 years. we diagnosed this patient with pituitary tsh-producing macroadenoma. thyroid hormone concentration was increasing although the serum tsh level was within a normal range after t ... | 2011 | 21519153 |
| full-dose capecitabine with local radiotherapy: one of the treatment options for inoperable t4 breast cancer. | a 48-year-old woman presented with a 15-cm diameter tumor in her left breast with fixation to the chest wall and palpable axillary lymph nodes. pathology study showed pure-type mucinous carcinoma. pretreatment staging investigations showed multiple lung metastases, which resulted in the diagnosis of t4n2m1 breast cancer. four cycles of cyclophosphamide 700 mg/m(2)/epirubicin 70 mg/m(2) (ce) were performed initially, but the tumors decreased only within the treatment response criteria of stable d ... | 2011 | 21519998 |
| [effective reversal of muscle relaxation by rocuronium using sugammadex in a patient with myasthenia gravis undergoing laparoscopic cholecystectomy]. | as myasthenia gravis affects neuromuscular transmission, these patients show various responses to neuromuscular blocking drugs. we report a successful use of the sugammadex in a myasthenic patient to reverse rocuronium-induced neuromuscular block. a 69-year-old woman was scheduled for laparoscopic cholecystectomy and total of rocuronium 20 mg was administered. after spontaneous recovery of t1, we administered sugammadex 200mg intravenously, reversing neuromuscular blockade to a train-of-four rat ... | 2011 | 21520600 |
| [bladder preservation using chemoradiation therapy for locally invasive bladder cancer]. | we investigated the long-term results and molecular markers of outcome with selective organ preservation in invasive bladder cancer using chemoradiation therapy. | 2011 | 21520632 |
| diagnosis and treatment of hypothyroidism in tsh deficiency compared to primary thyroid disease: pituitary patients are at risk of under-replacement with levothyroxine. | objective achieving optimal thyroid hormone replacement is more difficult in tsh deficiency compared to primary hypothyroidism because of the inability to be guided by serum tsh levels. a combination of clinical symptoms and free thyroxine levels (ft4) are typically used to make a diagnosis and monitor replacement. we investigated the diagnosis of tsh deficiency in patients with pituitary disease and the adequacy of levothyroxine replacement compared with primary thyroid disease. design using ... | 2011 | 21521256 |
| association of thyroid autoimmunity with acne in adult women. | background during the last decades an increase has been observed regarding acne in adults and especially women. objective to evaluate the association between thyroid disorder and the presence of post-adolescent acne in adult women, comparing with healthy controls. methods 107 adult women with post-adolescent acne and 60 healthy controls were included. complete blood count and standard biochemical profile of c-reactive protein (crp) and levels of thyroid hormones and antibodies [triiodothyroni ... | 2011 | 21521376 |
| hair regrowth with topical triiodothyronine ointment in patients with alopecia areata: a double-blind, randomized pilot clinical trial of efficacy. | background thyroid hormone receptors are expressed in hair follicles and it is known that thyroid hormones can have a positive effect on hair growth, i.e. process which is disrupted in alopecia areata. objectives the aim of this study was to determine the efficacy of topical triiodothyronine in patients with patchy alopecia areata. methods ten patients with patchy alopecia areata were treated with triiodothyronine and placebo applied twice daily to either of two bilaterally symmetrical patche ... | 2011 | 21521379 |
| inability of rhtsh to predict the evolution from subclinical hypothyroidism to overt disease. a pilot study. | background: the use of recombinant human tsh is indicated to evaluate thyroid carcinoma patients. in recent years, some authors have reported that rhtsh could serve as a dynamic test of thyroid reserve. the aim of the present study was to determine whether or not rhtsh can predict the evolution from subclinical hypothyroidism (sh) to overt hypothyroidism. materials and methods: twenty-one women who met the diagnostic criteria of sh were enrolled. all patients received a single dose of rhtsh (0.1 ... | 2011 | 21521938 |
| the influence of prognostic factors and adjuvant chemoradiation on survival after pancreaticoduodenectomy for ampullary carcinoma. | introduction: the prognosis after pancreaticoduodenectomy (pd) for ampullary carcinoma (ac) is superior to that of pancreatic cancer. decisions regarding adjuvant therapy are influenced by factors such as nodal status, stage, and grade, but the influence of these individual variables on survival is unclear. methods: a prospective tumor registry database was queried to identify patients who underwent pd for ac at thomas jefferson university between jan 1997 and apr 2009. the study was conducted w ... | 2011 | 21523621 |
| patterns of extralaryngeal spread of laryngeal cancer: thyroid cartilage penetration occurs in a minority of patients with extralaryngeal spread of laryngeal squamous cell cancers. | background: laryngeal preservation programs for patients with advanced laryngeal squamous cell carcinomas (scc) have generally excluded patients with t4 disease. the accuracy of preoperative imaging in evaluating thyroid cartilage penetration and extralaryngeal spread (els) has previously been questioned. clinically, scc spread into noncartilaginous structures may have less of a functional impact when compared with thyroid cartilage penetration. the current study was designed to characterize and ... | 2011 | 21523761 |
| expression and function role of dna methyltransferase 1 in human bladder cancer. | background: the identification of potential tumor markers will help improve therapeutic planning and patient management. therefore, the aim of this study was to highlight the role of dna methyltransferase 1 (dnmt1) in bladder cancer. methods: a total of 50 samples of nonmalignant urothelium, 65 of muscle-invasive bladder cancers, 15 of distant metastasis, and 50 of nonmuscle-invasive bladder cancers were selected for immunohistochemical staining analysis. furthermore, human bladder cancer cell l ... | 2011 | 21523767 |
| ultrasensitive microarray detection of short rna sequences with enzymatically modified nanoparticles and surface plasmon resonance imaging measurements. | a novel multiplexed method for short rna detection that employs an enzymatic capture reaction onto dna-modified silica nanoparticles (sinps) followed by nanoparticle-enhanced surface plasmon resonance imaging (spri) is demonstrated. sinps functionalized with 5'-phosphorylated single stranded dna (ssdna) are used with t4 rna ligase to capture various short 20-24 base single-stranded rna (ssrna) oligonucleotides from a target solution. the ssrna-modified sinps are collected from the target solutio ... | 2011 | 21524060 |
| metabolism and gastric remnant changes after roux-en-y gastric bypass in rats. | abstract background: the roux-en-y gastric bypass (rygb) may affect metabolism, microbiology, and histology of gastric remnant. therefore, this study aimed to investigate these issues in rats. methods: twelve rats were randomly allocated to a rygb group (n = 6) and nonoperated normal rats group (n = 6). after 30 postoperative days, all rats were injected with 0.1ml of na(99m)tc(-) i.v. (radioactivity 0.66 mbq). after 30 min, liver, stomach, thyroid, heart, lung, kidney, and femur samples were ha ... | 2011 | 21524176 |
| sequence characteristics of t4-like bacteriophage ime08 benome termini revealed by high throughput sequencing. | abstract: | 2011 | 21524290 |
| massive levothyroxine ingestion in a pediatric patient: case report and discussion. | abstractwe describe the course of a toddler who ingested a massive amount of levothyroxine and review treatment options for such overdoses. a 2½-year-old boy presented shortly after an ingestion of up to 7.6 mg of levothyroxine (potentially as much as 700 μg/kg). he was initially asymptomatic, treated with oral charcoal 1 g/kg, and discharged home from the emergency department after a few hours. he returned approximately 24 hours later with a temperature of 38.5°c, heart rate of 163 beats per mi ... | 2011 | 21524373 |
| correlation between fas and fasl proteins expression in normal gastric mucosa and gastric cancer. | the study's objective was to assess the expressions of fas and fasl proteins in gastric cancer in correlation with chosen clinicohistological parameters. fas and fasl expression was analyzed in 68 patients with gastric cancer, using the immunohistochemical method. the expression of fas was found to be lower in gastric cancer cells than in healthy mucosa, both in the lining epithelium and in glandular tubes (28% vs. 48% and 44%; p 〈 0.001). the expression of fasl was also markedly lower in cancer ... | 2011 | 21526501 |
| thyroid autoimmunity role in the evolution of endemic goiter in rural area, fars, iran. | who reports indicate no iodine insufficiency in iran, however, goiter is still endemic in fars province. this study evaluates the role of thyroid autoimmunity in the evolution of endemic goiter. | 2011 | 21529102 |
| treatment of a malignant peripheral nerve sheath tumor and its complications through a multidisciplinary approach. | the authors report the case of a 14-year-old girl with a residual malignant peripheral nerve sheath tumor after thoracotomy, chemotherapy, and radiation therapy. the residual tumor, which involved the intercostal muscles, aorta, and neural foramina of t4-10, was completely resected through a costotransversectomy and multiple hemilaminotomies with the patient in the prone position and was stabilized using a t1-12 pedicle screw fusion. postoperatively, the patient developed several infections requ ... | 2011 | 21529197 |
| titanium plates and dualmesh: a modern combination for reconstructing very large chest wall defects. | the reconstruction of large full-thickness chest wall defects after resection of t3/t4 non-small cell lung carcinomas or primary chest wall tumors presents a technical challenge for thoracic surgeons and plays a central role in determining postoperative morbidity. the objective is to evaluate our results in chest wall reconstruction using a combination of expanded polytetrafluoroethylene (eptfe) mesh and titanium plates. | 2011 | 21531380 |
| effects of hyperthyroidism, hypothyroidism and thyroid autoimmunity on female sexual function. | introduction: thyroid hormones affect male and female sexual functions, but data in hypo- and hyperthyroid women are scanty. aim: to investigate sexual function in hypo- and hyperthyroid women before and immediately after restoration of euthyroidism and in women with euthyroid hashimoto's thyroiditis (ht). patients and controls: fifty-six women with thyroid diseases (age 19-50 years; 22 with hyperthyroidism, 17 with hypothyroidism and 17 with euthyroid ht) and 30 age-matched healthy women. main ... | 2011 | 21532331 |
| male breast cancer: 22 case reports at the national hospital of niamey-niger (west africa). | male breast cancer (mbc) is rare. the objective of the study is to report clinicopathological characteristics, treatment patterns, and outcomes of mbc. | 2009 | 21532724 |
| rna captor: a tool for rna characterization. | in the genome era, characterizing the structure and the function of rna molecules remains a major challenge. alternative transcripts and non-protein-coding genes are poorly recognized by the current genome-annotation algorithms and efficient tools are needed to isolate the less-abundant or stable rnas. | 2011 | 21533245 |
| shine-dalgarno sequence of bacteriophage t4: gagg prevails in early genes. | translation initiation is governed by a limited number of mrna sequence motifs within the translation initiation region (tir). in bacteria and bacteriophages, one of the most important determinants is a shine-dalgarno (sd) sequence that base pairs with the anti-sd sequence gaucaccuccuua localized in the 3' end of 16s rrna. this work assesses a diversity of tir features in phage t4, focusing on the sd sequence, its spacing to the start codon and relationship to gene expression and essentiality pa ... | 2011 | 21533668 |
| thyroid status in a large cohort of patients with mental retardation: the top-r (thyroid origin of psychomotor retardation) study. | objective: abnormalities in thyroid state may affect development and function of the brain and result in mental retardation (mr). thyroid parameters have not been systematically investigated in institutionalized mr subjects. the objective is to measure thyroid parameters in a novel cohort of 946 institutionalized subjects. design: the top-r (thyroid origin of psychomotor retardation) study is a cross-sectional nation-wide multi-centre study. patients: subjects with unexplained mr. results: t ... | 2011 | 21535074 |
| supranutritional selenium level affects fatty acid composition and oxidative stability of chicken breast muscle tissue. | a total of 128 broilers were used to investigate the effect of selenium (se) on fatty acid (fa) composition and oxidative stability of lipids in the breast muscle tissue. there were 4 replicates of 4 dietary treatments: t1 (basal diet with no added se), t2 (t1 with 0.15 mg se added per kg diet), t3 (t1 with 0.3 mg se added per kg diet) and t4 (t1 with 3.0 mg se added per kg diet). a yeast source was used for added se. breast muscle tissue was collected from two chickens per replicate pen for the ... | 2011 | 21535232 |
| molecular characterization of a novel type ii keratin gene (sseker3) in the senegalese sole (solea senegalensis): differential expression of keratin genes by salinity. | keratins make up the largest subgroup of intermediate filaments and, in chordates, represent the most abundant proteins in epithelial cells. senegalese sole (solea senegalensis) is a commercially important flatfish in which only two type i keratin genes, sseker1 and sseker2, have been described. we obtained the entire cdnas encoding for a novel type ii keratin, referred to as sseker3. main features and sequence identities with other fish and mammalian type ii keratins are described. expression p ... | 2011 | 21536146 |
| [comparative study of oncologic outcomes after multivisceral resection for stage iic colorectal cancer between inflammatory and malignant adhesion]. | to evaluate the differences in oncologic outcomes between inflammatory adhesion and malignant adhesion in patients with stage iic colorectal cancer after multivisceral resection(mvr). | 2011 | 21538269 |
| electroneutral cation-cl(-) cotransporters nkcc2β and nccβ expressed in the intestinal tract of japanese eel anguilla japonica. | in the present study, we aimed to elucidate the mechanisms of intestinal na(+) and cl(-) absorption in japanese eel, focusing on electroneutral cation-cl(-) cotransporters, nkcc2β and nccβ, expressed in the intestinal tract. first, we cloned cdnas encoding nkcc2β and nccβ from the intestinal tract of japanese eel. in both freshwater- and seawater-acclimated eels, quantitative pcr analysis showed that nkcc2β was predominantly expressed in the anterior and posterior intestines, and that nccβ expre ... | 2011 | 21539929 |
| multivariable analysis of factors associated with hospital readmission following pancreaticoduodenectomy for malignant diseases. | readmission rates after pancreaticoduodenectomy (pd) for malignant diseases have a significant impact on survival rate. identification of risk factors for readmission may improve discharge plans and postoperative care. data exist on the morbidity and mortality of patients undergoing pd, but there are few reports about hospital readmissions after this procedure. our aims were to evaluate the proportion and reasons for readmissions after pd for malignant diseases, the factors influencing readmissi ... | 2011 | 21542962 |
| genetic causes of congenital hypothyroidism due to dyshormonogenesis. | purpose of review: overview of congenital hypothyroidism caused by thyroid hormone synthesis defects, the current understanding of their pathophysiology, and clinical implications of molecular diagnoses. recent findings: genetic defects in all known thyroid-specific factors required for thyroid hormone synthesis have been described. these include defects in iodide trapping (nis), in the facilitated iodide efflux across the apical membrane (pds), the organification of iodide within the follicular ... | 2011 | 21543982 |
| synthesis of maleimide-end functionalized star polymers and multimeric protein-polymer conjugates. | protein-polymer conjugates exhibit superior properties to unmodified proteins, generating a high demand for these materials in the fields of medicine, biotechnology, and nanotechnology. multimeric conjugates are predicted to surpass the activity of monomeric conjugates. herein, we report a straightforward method to synthesize multimeric polymer-conjugates. four armed poly(n-isopropylacrylamide) (pnipaam) was synthesized by reversible addition-fragmentation chain transfer (raft) polymerization in ... | 2009 | 21544227 |
| axillary lymph node metastases detection with nuclear medicine approaches in patients with newly diagnosed breast cancer. | three different tracers, tc-99m-sesta mibi, in-111-pentetreotide and f-18-fdg, were evaluated in a preliminary study in three different groups of 10 breast cancer patients programmed for breast cancer resection and axillary dissection. planar scintigraphy and single photon emission tomography (spet) technique were used for imaging with tc-99m-sesta-mibi and in-111-pentetreotide, positron emission tomography (pet) was used for imaging with f-18-fdg. we studied 30 breast cancer patients; their cli ... | 1996 | 21544415 |
| developmental associations between externalizing behaviors, peer delinquency, drug use, perceived neighborhood crime, and violent behavior in urban communities. | this study examines the precursors of violent behavior among urban, racial/ethnic minority adults. data are from an on-going study of male and female african americans and puerto ricans, interviewed at four time waves, time 1-time 4 (t1-t4), from adolescence to adulthood. structural equation modeling was used to analyze the developmental pathways, beginning in mid-adolescence (t1; age = 14.0 years), to violent behavior in adulthood (t4; age = 29.2 years). the variables assessed were: components ... | 2011 | 21544831 |
| toxicologic and immunologic effects of perinatal exposure to the brominated diphenyl ether (bde) mixture de-71 in the sprague-dawley rat. | brominated diphenyl ethers (bdes) are persistent environmental contaminants found in human blood, tissues, and milk. to assess the impact of the commercial bde mixture de-71 on the developing immune system in relation to hepatic and thyroid changes, adult (f0) rats were exposed to de-71 by gavage at doses of 0, 0.5, 5, or 25 mg/kg body weight (bw)/d for 21 weeks. f0 rats were bred and exposure continued through gestation, lactation and postweaning. f1 pups were weaned and exposed to de-71 by gav ... | 2011 | 21544923 |
| thyroid dysfunction following therapeutic external radiation to head and neck cancer. | aim: the aim of the present study was to evaluate changes in thyroid function in patients with head and neck cancer treated with external beam radiotherapy (ebrt). materials and methods: this prospective study was conducted on ninety patients with non-thyroid head and neck cancer who were referred to the department of radiotherapy. thyroid function tests were conducted before, midway during and after ebrt, with follow up at monthly intervals up to 6 months after the completion of therapy. result ... | 2011 | 21545210 |
| accumulation and debromination of decabromodiphenyl ether (bde-209) in juvenile fathead minnows (pimephales promelas) induces thyroid disruption and liver alterations. | polybrominated diphenyl ether (pbde) flame retardants are known to affect thyroid hormone regulation. the thyroid hormone regulating deiodinases have been implicated in these impacts; however, pbde effects on the fish thyroid system are largely unknown. moreover, the liver as a potential target of pbde toxicity has not been explored in young fish. this study measured bde-209 effects on thyroid hormone regulation by measuring deiodinase activity in juvenile fathead minnows (pimephales promelas). ... | 2011 | 21546348 |
| [application of anterolateral thigh myocutaneous flap in the reconstruction of tongue and mouth floor defect after tongue carcinoma]. | to investigate the application of free anterolateral thigh myocutaneous flap in the reconstruction of tongue and mouth floor defect after radical resection of tongue carcinoma. | 2011 | 21548379 |
| sentinel-lymph-node procedure in colon and rectal cancer: a systematic review and meta-analysis. | no consensus exists on the validity of the sentinel-lymph-node procedure for assessment of nodal status in patients with colorectal cancer. we aimed to assess the diagnostic performance of this procedure. | 2011 | 21549638 |
| association of chfr promoter methylation with disease recurrence in locally advanced colon cancer. | purpose: this study was designed to determine whether dna methylation biomarkers are associated with recurrence and survival in colon cancer patients. experimental design: a retrospective analysis of 82 patients who received curative surgical resection for ajcc high-risk stage ii or iii colon cancer (1999-2007) was conducted. dna methylation status was quantitatively evaluated by the pyrosequencing method. we preselected three tumor-suppressor genes and one locus of interest; chfr, id4, reck, an ... | 2011 | 21551253 |
| algoriphagus aquaeductus sp. nov., isolated from a freshwater pipe. | a gram-negative, aerobic to microaerophilic, rod-shaped, red-colored bacterium, strain t4(t), was isolated from a freshwater pipe on tenerife island. a polyphasic taxonomic study was performed in order to characterise the strain in detail. the isolate is surrounded by a slime capsula and occurs single, in form of short chains, or in aggregates and exhibits catalase and oxidase activities. growth was observed at 15-42 °c. best growth of the bacterium occurred at ph 8 with mono- and disaccharides, ... | 2011 | 21551331 |
| experimental hyperthyroidism enhances the regeneration of central neurites promoted by peripheral nerve grafts in the hippocampus. | the aim of the present paper was to ascertain whether experimental hyperthyroidism promotes the regenerative action of predegenerated peripheral nerve grafts implanted into the transected hippocampus. hyperthyroidism was induced by subcutaneous injections of t4. autologous peripheral nerve grafts were implanted immediately, 7 and 35 days following transection of the sciatic nerve. cells extending their neurites into the grafts were traced by means of horseradish peroxidase conjugated with fluore ... | 1993 | 21551731 |
| [influence of pre-operative fasting time on blood glucose in older patients.] | purpose: this study was performed to identify changes in blood glucose at preoperative fasting time in surgical patients over 60 yr. methods: data collection was performed from july, 2008 through july, 2009. participants consisted of 80 nondiabetic surgical patients. blood glucose was checked from 3 to 5 times. the 5 times were 2-hr fasting on the pre-operative day (t1, n=80), 8 hr (t2, n=80), 10 hr (t3, n=17), 12 hr (t4, n=34) and 14 hr fasting on the day of the operation (t5, n=29). results: o ... | 2011 | 21551986 |
| biochemistry of eukaryotic homologous recombination. | the biochemistry of eukaryotic homologous recombination caught fire with the discovery that rad51 is the eukaryotic homolog of the bacterial reca and t4 uvsx proteins; and this field is still hot. the core reaction of homologous recombination, homology search and dna strand invasion, along with the proteins catalyzing it, are conserved throughout evolution in principle. however, the increased complexity of eukaryotic genomes and the diversity of eukaryotic cell biology pose additional challenges ... | 2007 | 21552479 |
| prognostic factors for locoregional recurrence and survival in stage iiic breast carcinoma: impact of adjuvant radiotherapy. | introduction: the aims of the present study were to define the prognostic factors for locoregional recurrence (lrr) and survival in stage iiic breast carcinoma as well as to examine the impact of adjuvant radiotherapy on the outcome of the disease. methods: the records of 586 consecutive patients with stage iiic breast carcinoma who underwent modified radical mastectomy were evaluated, and the prognostic factors for lrr and survival were analysed. survival curves were generated using the kaplan- ... | 2011 | 21552792 |
| evaluation of factors affecting post-treatment quality of life in oral and oropharyngeal cancer patients primarily treated with curative surgery: an exploratory study. | the aim was to explore the impact of important clinico-demographic factors on the post-treatment quality of life (qol) in surgically treated oral and oropharyngeal cancer patients. 63 consecutive follow-up oral and oropharyngeal cancer patients treated primarily with surgery were recruited. 55 patients sent the completed questionnaires and finally included in this study. qol and important sub-domains of the qol were assessed. mean qol scores (sd) were computed, level of significance was set at p ... | 2011 | 21553147 |
| increased risk of advanced prostate cancer associated with mnsod ala-9-val gene polymorphism. | we aimed to investigate the association between manganese superoxide dismutase (mnsod) ala-9-val gene polymorphism and the initiation and/or progression of prostate cancer (pca) as well as to evaluate its potential interactions with advanced age and smoking status. mnsod ala-9-val gene polymorphism was carried out in 134 (mean age 64.1 ± 7.48) pca patients and 159 (mean age 62.5 ± 7.53) healthy controls with serum prostate specific antigen (psa) levels (<4 ng/ml) and normal digital rectal examin ... | 2011 | 21553226 |
| clinical significance of lymph node ratio and location of nodal involvement in patients with right colon cancer. | background/aims: increasing negative lymph node count has been reported to be associated with better outcomes in patients with colon cancer. the present study aimed to clarify the clinical significance of the lymph node ratio (lnr) and location of lymph node metastasis (lnm) in patients with stage iii right colon cancer. methods: we enrolled 820 patients who had undergone curative resection due to colon cancer at a single institution between 1991 and 2005. among them, 197 underwent curative rese ... | 2011 | 21555889 |
| neoadjuvant accelerated concomitant boost radiotherapy and multidrug chemotherapy in locally advanced rectal cancer: a dose-escalation study. | objectives: to determine the maximal and safely dose of preoperative radiotherapy and concurrently intensified chemotherapy regimen (raltitrexed plus oxaliplatin) in locally advanced rectal cancer patients. methods: patients with ct3-t4 and/or cn≥1 or locally recurrent rectal cancer were sequentially assigned to 4 treatment schedules of chemoradiation: standard radiotherapy (50.4 gy/5.5 wk) plus raltitrexed (cohort a), accelerated radiotherapy (55 gy/5 wk) plus raltitrexed (cohort b), standard r ... | 2011 | 21555930 |
| chromosome-11q13 gene amplifications in head and neck squamous-cell carcinomas - relation with lymph-node invasion. | gene amplifications occurring in the q13 band of chromosome 11 are frequently observed in head and neck squamous cell carcinomas. in order to determine the relative frequency of amplification in 5 distinct 11q13 loci and their relation with clinical data, tumor dnas from 31 patients - including 26 who had undergone neck dissection (lymph node histology available) - were evaluated by southern blot. specific probes were used for the d11s833e, fgf3, cycd1, d11s97 and gst-pi loci. the most frequentl ... | 1994 | 21559590 |
| optimal margins and lymphadenectomy in colonic cancer surgery. | background: a standard management policy has not yet been established with respect to the extent of lymphadenectomy for colonic cancer. methods: a total of 914 consecutive patients who underwent potentially curative surgery for t2-t4 colonic cancer were reviewed retrospectively. the number of lymph nodes (lns) examined and the potential contributions to the staging accuracy of the distinct area were analysed. the survival benefit of dissection was compared for pericolic (local), mesocolic (inter ... | 2011 | 21560120 |
| genetic variation in the toll-like receptor 4 and prostate cancer incidence and mortality. | background: common genetic variants in the toll-like receptor 4 (tlr4), which is involved in inflammation and immune response pathways, may be important for prostate cancer. methods: in a large nested case-control study of prostate cancer in the physicians' health study (1982-2004), 10 single nucleotide polymorphisms (snps) were selected and genotyped to capture common variation within the tlr4 gene as well as 5 kb up and downstream. unconditional logistic regression was used to assess associati ... | 2011 | 21563195 |
| feasibility study for a controllable orthotic knee joint. | purpose. the purpose of this study was to demonstrate the feasibility of producing an orthotic knee joint that could lock and unlock during ambulation for eventual use in a reciprocating gait orthosis (rgo) for severely disabled patients. method. three prototype orthotic knee joints incorporating braking mechanisms were designed and manufactured to demonstrate their ability to withstand a maximum calculated sagittal plane bending moment of 73 nm. each was then subjected to bench trials to test t ... | 2011 | 21563970 |
| thyroid function after controlled ovarian hyperstimulation in women with and without the hyperstimulation syndrome. | objective: to investigate the impact of ovarian hyperstimulation syndrome (ohss) on thyroid function in women without thyroid disorders and to compare it with that in women with uncomplicated controlled ovarian hyperstimulation (coh). design: retrospective analysis. setting: tertiary referral fertility center. patient(s): a total of 77 women undergoing coh of whom 25 developed ohss and 52 had no ohss. women with the presence of thyroid disorders were excluded, and only women pregnant after assis ... | 2011 | 21565336 |
| halogenated phenolic contaminants inhibit the in vitro activity of the thyroid regulating deiodinases in human liver. | halogenated contaminants, particularly brominated flame retardants, disrupt circulating levels of thyroid hormones (th), potentially affecting growth and development. disruption may be mediated by impacts on deiodinase (di) activity, which regulate the levels of active hormones available to bind to nuclear receptors. the goal of this study was to develop a mass spectrometry based method for measuring the activity of dis in human liver microsomes and to examine the effect of halogenated phenolic ... | 2011 | 21565810 |
| outcome of congenitally hypothyroid screening program in isfahan: iran from prevention to treatment. | early and proper treatment is crucial to prevent neuropsychologic deficits in congenital hypothyroidism (ch). considering the high prevalence of ch in isfahan, the aim of this study was to evaluate the outcome of treatment in ch patients. | 2010 | 21566768 |
| altered levels of the onco-microrna 21 and the tumor-supressor micrornas 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy. | micrornas (mirnas) are small non-coding rnas with important post-transcriptional regulatory functions. mirna-21 (mir-21) is upregulated and mir-143 and mir-145 are downregulated in colorectal carcinoma. the aim of our study was to determine if these mirnas change their expression levels in response to neoadjuvant chemoradiotherapy in advanced rectal cancer. forty patients with advanced rectal cancer (clinical ut3/t4 nx) were included. all patients underwent neoadjuvant chemoradiotherapy and surg ... | 2011 | 21567082 |
| thermoprecipitation of glutathione s-transferase by glutathione-poly(n-isopropylacrylamide) prepared by raft polymerization. | herein, we report an effective and rapid method to purify glutathione s-transferase (gst) using glutathione (gsh)-modified poly(n-isopropylacrylamide) (pnipaam) and mild, thermal conditions. a chain transfer agent modified with pyridyl disulfide was employed in the reversible addition-fragmentation chain transfer (raft) polymerization of nipaam. the resulting polymer had a narrow molecular weight distribution (polydispersity index = 1.21). conjugation of gsh to the pyridyl disulfide-pnipaam reac ... | 2010 | 21567582 |
| a preliminary report on the effects of the level of spinal cord injury on the association between central adiposity and metabolic profile. | to determine the effects of the level of injury on visceral adipose tissue (vat), subcutaneous adipose tissue (sat), and the vat:sat ratio in individuals with tetraplegia (t-spinal cord injury [sci]) and paraplegia (p-sci) and the relationships among central adiposity and glucose and lipid profile. | 2011 | 21570032 |
| anal canal cancer: management of inguinal nodes and benefit of prophylactic inguinal irradiation (cors-03 study). | purpose: to evaluate the benefit of prophylactic inguinal irradiation (pii) in anal canal squamous cell carcinoma (ascc). methods and materials: this retrospective study analyzed the outcome of 208 patients presenting with ascc treated between 2000 and 2004 in four cancer centers of the south of france. results: the population study included 35 t1, 86 t2, 59 t3, 20 t4, and 8 t stage unknown patients. twenty-seven patients presented with macroscopic inguinal node involvement. of the 181 patients ... | 2011 | 21570207 |
| moyamoya disease presenting as thalamic hemorrhage in a patient with neuromyelitis optica and sjögren's syndrome. | a 52-year-old woman was admitted to the hospital with right thalamic hemorrhage. a carotid angiogram revealed occlusion of the terminal portions of the bilateral internal carotid arteries with basal moyamoya vessels, which was diagnosed as moyamoya disease (mmd). at 31 years of age, she was diagnosed with multiple sclerosis because of optic neuritis and myelitis. paraplegia appeared 14 days after admission. t2-weighted thoracic magnetic resonance imaging revealed a high intensity lesion extendin ... | 2011 | 21571549 |
| the bacteriophage t4 rapid-lysis genes and their mutational proclivities. | like most phages with double-stranded dna, phage t4 exits the infected host cell by a lytic process requiring, at a minimum, an endolysin and a holin. unlike most phages, t4 can sense superinfection (which signals the depletion of uninfected host cells) and responds by delaying lysis and achieving an order-of-magnitude increase in burst size using a mechanism called lysis inhibition (lin). t4 r mutants that are unable to conduct lin produce distinctly large, sharp-edged plaques. the discovery of ... | 2011 | 21571993 |
| chromosomal markers as prognostic indicators in transitional-cell carcinomas of the bladder. | clinical-cytogenetic correlations were assessed in 79 patients with transitional cell carcinomas of the bladder to whom cytogenetic analysis of the primary tumor had been successful. high-grade (g2+g3) and high-stage (t2-t4) tumors had in general a higher ploidy level and contained more marker chromosomes, including multiple markers, compared to low-grade (g0+g1) and low stage (ta+t1) tumors. the early recurrence rate (within 7 months) was significantly higher (p<0.05) in patients whose tumors c ... | 1993 | 21573351 |
| immunoassay for thymidylate synthase in cytosols from human colorectal-carcinoma cell-lines. | thymidylate synthase (ts) is an essential enzyme for dna biosynthesis that is an important target of fluoropyrimidine anti-cancer drugs such as 5-fluorouracil (5-fu), which is frequently used against human colon adenocarcinomas. because levels of ts in such tumors may be predictive of chemotherapeutic response to 5-fu, it is desirable to have a method for ts quantitation simpler than the laborious conventional biochemical assays that currently exist. we therefore describe a rapid and simple immu ... | 1993 | 21573550 |
| survival benefit of bursectomy in patients with resectable gastric cancer: interim analysis results of a randomized controlled trial. | background: bursectomy is regarded as a standard surgical procedure during gastrectomy for serosa-positive gastric cancer in japan. there is little evidence, however, that bursectomy has clinical benefit. we conducted a randomized controlled trial to demonstrate non-inferiority of treatment with the omission of bursectomy. methods: between july 2002 and january 2007, 210 patients with ct2-t3 gastric adenocarcinoma were intraoperatively randomized to radical gastrectomy and d2 lymphadenectomy wit ... | 2011 | 21573917 |
| impact of endothelial activation on infective and inflammatory complications after cardiac surgery in type ii diabetes mellitus. | purpose: altered endothelial response has been described in diabetics after cardiac surgery. infections and inflammatory organ damage often complicate the postoperative course. we evaluated endothelial/cytokine response (ecr) after cardiac surgery and its role on infective/inflammatory complications of type ii diabetic patients. ?methods: perioperative ecr of 60 diabetic patients (group a) undergoing cardiopulmonary bypass was compared to that of 60 non-diabetics (group b). hemodynamics, endothe ... | 2011 | 21574159 |
| [analysis of the therapeutic efficacy for 60 cases of t4 squamous cell carcinoma of the pyriform sinus]. | to evaluate the treatment results of t4 squamous cell carcinoma of the pyriform sinus. | 2011 | 21575488 |
| [surgery for t4 hypopharyngeal cancer and reconstruction after hypopharyngo-oesphagectomy.] | objective: to explore the surgical treatment of hypopharyngeal and cervical esophageal cancers and the ways of reconstruction after hypopharyngo-oesphagectomy, and to evaluate their efficacy. methods: twenty five patients with cancer of the laryngopharynx and cervical esophagus treated in our department between 1995 and 2007 were included in this study. their clinical data were restrspectively analyzed. among them, 17 cases had the tumor originated from the pyriform sinus, 3 of the posterior pha ... | 2011 | 21575524 |
| phenazine-naphthalene-1,5-diamine-water (1/1/2). | the asymmetric unit of the title compound, c(12)h(8)n(2)·c(10)h(10)n(2)·2h(2)o, contains one half-mol-ecule of phenazine, one half-mol-ecule of naphthalene-1,5-diamine and one water mol-ecule. the phenazine and naphthalene-1,5-diamine mol-ecules are located on inversion centers. the water mol-ecules serve as bridges between the naphthalene-1,5-diamine mol-ecules and also between the naphthalene-1,5-diamine and phenazine mol-ecules. the naphthalene-1,5-diamine and water mol-ecules are connected v ... | 2009 | 21578891 |
| [effect of the populations of alabama argillacea (hübner) (lepidoptera: noctuidae) on cotton crop at two sowing distances.] | the objective of this research was to evaluate the incidence of damage by the leafworm alabama argillacea (hübner) on yields of cotton grown under rows spaced 0.38 m and 0.76 m at the irrigation area of santiago del estero, argentina. the period evaluated was extended from first flower to first open boll. treatments were t1 - without control of larvae, t2 - with control of larvae, t3 - control since first flower to the end of effective blooming, and t4 - with larval control since the end of effe ... | 2011 | 21584408 |
| preoperative radiotherapy for muscle-invading bladder-carcinoma. | one hundred five patients with clinical stage t2-t4 transitional cell bladder carcinoma who completed either low-dose (20-26 gy) or high dose (40-50 gy) preoperative radiotherapy (rt) followed by cystectomy were reviewed. five-year actuarial survival was 42%, 52%, and 17% for stages t2, t3, and t4, respectively. five-year local control rates for stages t2, t3, and t4 was 93%, 93% and 22%, respectively. survival, local control, distant metastasis and complications were similar for both preoperati ... | 1992 | 21584580 |
| splenic artery invasion in pancreatic adenocarcinoma of the body and tail: a novel prognostic parameter for patient selection. | background: the value of splenic vessels invasion (which identified t3 tumors) in prognosis after resection for pancreatic ductal adenocarcinoma (pda) of the body and tail has not been extensively investigated. the goal of this study was to evaluate prognostic factors in pda of the body/tail, emphasizing the role of splenic vessels infiltration. methods: between 1990 and 2008, 87 patients who underwent distal pancreatectomy (dp) for histologically proven pda of the body and tail were analyzed. c ... | 2011 | 21584836 |
| detection of bladder cancer using novel dna methylation biomarkers in urine sediments. | background: bladder cancer remains a lethal malignancy that can be cured if detected early. dna hypermethylation is a common epigenetic abnormality in cancer that may serve as a marker of disease activity.methods: we selected 10 novel candidate genes from the most frequently hypermethylated genes detected by dna microarray and bisulfite pyrosequencing of bladder cancers and applied them to detect bladder cancer in urine sediments. we analyzed dna methylation in the candidate genes by quantitativ ... | 2011 | 21586619 |
| peripheral nerve stimulation of the thoracic paravertebral plexus for chronic neuropathic pain. | persistent post surgical pain is reported in 70% of patients following thoracotomy and mastectomy. this pain is often neuropathic in nature and occasionally it is refractory to traditional medical and interventional management. neurostimulation of peripheral nerves can be a highly effective clinical modality for the management of neuropathic pain. the placement of a percutaneously sited electrode in the thoracic paravertebral plexus offers a new and novel mode of managing refractory thoracic neu ... | 2011 | 21587333 |
| vascular endothelial growth factor expression correlates with hematogenous metastasis and prognosis in colorectal carcinoma. | we investigated the expression of vascular endothelial growth factor (vegf) in 175 colorectal carcinomas by immunohistochemistry. vegf expression was correlated with advanced tnm stage (iii, iv), advanced t stage (t3, t4), vessel involvement, lymph node metastasis, and liver metastasis. with regard to the prognosis, both overall and relapse-free survival was significantly poorer, and furthermore, the hematogenous recurrences were significantly more commonly found in the patients with vegf-positi ... | 1997 | 21590063 |
| high urinary hydroxyproline excretion in patients with advanced head and neck cancer. | we studied the urinary excretion of hydroxyproline, measured as the hydroxyproline-to-creatinine ratio (hop/cr), in sixty-six patients with head and neck disease including, 18 patients with head and neck cancer. urinary hydroxyproline excretion was determined before treatment by the linear gradient elution method. although the urinary excretion of hydroxyproline is considered to be useful in monitoring cancer tissue such as prostate carcinomas, no studies have been performed on the urinary excre ... | 1997 | 21590105 |
| thyroid hormone-induced haemoglobin changes and antioxidant enzymes response in erythrocytes. | thyroid hormones modulate haemoglobin and reactive oxygen species (ros) production, leading to antioxidant changes. this study evaluated the antioxidant response to ros in erythrocytes in hypothyroid and hyperthyroid rats. wistar rats were divided into four groups: control; hyperthyroid (t(4) -12 mg l(-1) in drinking water); sham operated (simulation of thyroidectomy); and hypothyroid (thyroidectomized). four weeks after, blood was collected and haemoglobin and t(4) levels, lipid peroxidation (l ... | 2011 | 21590696 |
| exaggeration is harder than understatement, but practice makes perfect! | previous research on the fakeability of the implicit association test (iat) yielded inconsistent results. the present study simultaneously analyses several relevant factors: faking direction, type of instructions, and practice. furthermore, it takes baseline individual differences into account. after a baseline assessment in a self-esteem iat without faking instructions (t0), participants in the faking conditions then (t1) faked high or low scores without being provided with recommended strategi ... | 2011 | 21592941 |
| long-term outcome of idiopathic hypertrophic thoracic pachymeningitis. | idiopathic hypertrophic spinal pachymeningitis (ihsp) is a comparatively rare disease characterized by hypertrophic inflammation of the dura mater and clinical symptoms that progress from local pain to myelopathy. we report a case of ihsp followed up for 20 years in a 46-year-old man. expansive laminoplasty was performed in 1991, and this case has been previously reported by a co-author. after 17 years, the patient's gait disturbance returned. physical examination and imaging confirmed ihsp that ... | 2011 | 21594749 |
| phase selection and site-selective distribution by tin and sulfur in supertetrahedral zinc gallium selenides. | doping is among the most important methods to tune the properties of semiconductors. for dense phase semiconductors, the distribution of dopant atoms in crystal lattices is often random. however, when the size of semiconductors becomes increasingly smaller and reaches the extreme situation as is the case in chalcogenide supertetrahedral clusters, different chemically distinct sites (e.g., corner, edge, face, and core) occur, which can dramatically affect the doping chemistry at different sites a ... | 2011 | 21595469 |
| [effect of the levels of vascular endothelial growth factor-a and c on the prognosis of patients with larynx carcinoma.] | objectives: in this study, we determined the prognostic importance of vascular endothelial growth factor (vegf)-a and c values and their relationship with tumor stages and neck lymp node involvement and also, the relationship between microvessel density and tumor stage in the pathologic specimens. patients and methods: thirty-three male patients (mean age 57.8±7.2 years; range 49 to 69 years) who underwent surgical treatment for laryngeal squamous cell carcinoma and a control group of 13 healthy ... | 2011 | 21595615 |