Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| Broad spectrum antidermatophytic drug for the control of tinea infection in human beings. | During antifungal evaluation of various plant extracts, free and bound flavonoids of Piper betle were found to be most effective as an antidermatophytic against human pathogenic dermatophytes Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum gypseum and Candida albicans. Dermatophytic fungi cause both superficial and internal mycoses. These mycoses, although normally not lethal, are unpleasant and difficult to cure and cause considerable financial losses. Earlier workers prove that a ... | 2011 | 21929713 |
| anthraquinone profile, antioxidant and antimicrobial properties of bark extracts of rhamnus catharticus and r. orbiculatus. | the anthraquinone profile, antioxidant and antimicrobial activities as well as the total phenol and total flavonoid contents were determined in methanol extracts of the barks of rhamnus catharticus l. and r. orbiculatus bornm. the most abundant anthraquinone derivatives in r. catharticus were physcion (67.8%) and emodin (26.2%), while r. orbiculatus contained mostly physcion (81.3%) and chrysophanol (14.6%). r. catharticus displayed better activity in the beta-carotene-linoleic acid assay, as we ... | 2011 | 21941897 |
| Identification of rare macroconidia-producing dermatophytic fungi by real-time PCR. | To understand the pathogenicity and clinical significance of dermatophytes (also known as ringworms), the correct identification of these molds is essential. However, in routine practice they are notoriously difficult to classify and identify. The morphology of macroconidia, which are abundantly produced under suitable in vitro conditions, have provided useful criteria for the identification of many of the dermatophytes. However, several of them, including Microsporum audouinii, M. ferrugineum, ... | 2011 | 21954954 |
| design, synthesis and antifungal activity of some new imidazole and triazole derivatives. | triazole and imidazole are incorporated into the structures of many antifungal compounds. in this study a novel series of 1,2,4-triazole, imidazole, benzoimidazole, and benzotriazole derivatives was designed as inhibitors of cytochrome p450 14α-demethylase (14dm). these structures were docked into the active site of mt-cyp51, using autodock program. sixteen compounds with the best binding energy were synthesized. the chemical structures of the new compounds were confirmed by elemental and spectr ... | 2011 | 21984016 |
| outbreak of tinea capitis and corporis in a primary school in antananarivo, madagascar. | tinea capitis is common among schoolchildren in developing countries but underreported in madagascar. we report the occurrence of an outbreak of gray patch tinea capitis due to microsporum langeronii in a public primary school of antananarivo, the capital city of madagascar. | 2011 | 21997943 |
| tinea faciei due to microsporum canis in children: a survey of 46 cases in the district of cagliari (italy). | dermatophytoses are frequent in children, but involvement of the facial skin has peculiar aspects that should be considered a separate entity: tinea faciei. microsporum canis infection in tinea faciei has not been widely documented. to review cases of tinea faciei due to m. canis in children diagnosed at the dermatology clinic, university of cagliari. between 1990 and 2009, all children with dermatophyte infections of the facial skin were recruited for the study after parental consent. diagnosis ... | 2011 | 22011084 |
| brittle tail syndrome is an emerging infection in horses caused by a keratinolytic fungus equicapillimyces hongkongensis gen. nov., sp. nov. | the newly described brittle tail syndrome causes weakening and breakage of the tail hair of horses. extensive mycological and molecular studies showed that a novel fungus equicapillimyces hongkongensis gen. nov., sp. nov. is the most likely cause of this syndrome. it is a septate branching hyaline mould which grows optimally at 30°c, requires nicotinic acid but is inhibited by cycloheximide, and specifically infects horse hair. hyphae fill the core of infected hair shafts with short-necked struc ... | 2011 | 22014601 |
| Difference in keratinase activity of dermatophytes at different environmental conditions is an attribute of adaptation to parasitism. | Dermatophytes are a group of morphologically and physiologically related moulds, which cause well-defined infection called dermatophytosis. The enzymatic ability of fungi to decompose keratin has long been interpreted as a key innovation in the evolution of animal dermatology. In the present study, keratinase activity profile among Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis and Microsporum gypseum isolated on keratin substrates such as human hair, human nail and chicken ... | 2011 | 22032519 |
| [superficial mycoses in the city of valparaiso, chile: period 2007-2009]. | superficial mycoses are infections of the keratinous tissue caused by dermatophytes, yeasts and environmental fungi. | 2011 | 22051613 |
| mating genes of the trichophyton mentagrophytes complex. | the mating type (-)-specific gene of the alpha-box and the mating type (+)-specific gene of the high-mobility group (hmg) dna-binding domain were confirmed in zoophilic dematophytes of arthroderma simii and a. vanbreuseghemii. the sequence of the alpha-box gene was 1,375 bp, containing 2 exons (from 172 to 463 bp and from 513 to 1,375 bp) in the a. simii (-) mating type strain and 1,380 bp, containing 2 exons (from 177 to 468 bp and from 518 to 1,380 bp) in the a. vanbreuseghemii (-) mating type ... | 2011 | 22057847 |
| antifungal property of quaternized chitosan and its derivatives. | five water-soluble chitosan derivatives were carried out by quaternizing either iodomethane or n-(3-chloro-2-hydroxypropyl) trimethylammonium chloride (quat188) as a quaternizing agent under basic condition. the degree of quaternization (dq) ranged between 28±2% and 90±2%. the antifungal activity was evaluated by using disc diffusion method, minimum inhibitory concentration (mic) and minimum fungicidal concentration (mfc) methods against trichophyton rubrum (t. rubrum), trichophyton mentagrophyt ... | 2012 | 22100980 |
| preparation and evaluation of dermal delivery system of griseofulvin containing vitamin e-tpgs as penetration enhancer. | griseofulvin, an antifungal agent, is a bcs class ii drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. the clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter- and intra-subject variation in bioavailability from different commercial products. moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. the purp ... | 2011 | 22130790 |
| Interkingdom Gene Transfer of a Hybrid NPS/PKS from Bacteria to Filamentous Ascomycota. | Nonribosomal peptides (NRPs) and polyketides (PKs) are ecologically important secondary metabolites produced by bacteria and fungi using multidomain enzymes called nonribosomal peptide synthetases (NRPSs) and polyketide synthases (PKSs), respectively. Previous phylogenetic analyses of fungal NRPSs and PKSs have suggested that a few of these genes were acquired by fungi via horizontal gene transfer (HGT) from bacteria, including a hybrid NPS/PKS found in Cochliobolus heterostrophus (Dothideomycet ... | 2011 | 22140558 |
| Assessment of antimicrobial, insecticidal and genotoxic effects of Melia azedarach L. (chinaberry) naturalized in Anatolia. | In this study, antibacterial, antifungal, insecticidal and genotoxic activities of the fruit and leaf extracts of Melia azedarach of Turkish origin were evaluated for the first time. The antimicrobial activity was assessed against Gram (+) and ( - ) bacteria, four Candida species and three dermatophytic fungus (Trichophyton rubrum, Epidermophyton floccosum and Microsporum gypseum). The insecticidal activity of the methanolic fruit extract was performed against the larvae of Aedes aegpyti, Culex ... | 2011 | 22149768 |
| isolation of the volatile oil from satureja thymbra by supercritical carbon dioxide extraction: chemical composition and biological activity. | satureja thymbra l. is well known in italy by the popular name of "santoreggia sarda". it grows only in sardinia and nowadays it is restricted to the slope of the colle san michele in cagliari. the composition of the aromatic extracts obtained by supercritical co2 and by hydrodistillation and their antifungal activity is reported. the collected extracts were analyzed by gc-fid and gc-ms methods. no significant differences were observed in the composition of the volatile extracts depending on the ... | 2011 | 22164799 |
| Chemical composition and biological activity of the volatile extracts of Achillea millefolium. | In this study, flowering aerial parts of wild Achillea millefolium growing on the Mediterranean coast (Sardinia Island, Italy) and on the Atlantic coast (Portugal- Serra de Montemuro) were used as a matrix for supercritical extraction of volatile oil with CO2 (SFE). The collected extracts were analyzed by GC-FID and GC-MS methods and their composition were compared with that of the essential oil isolated by hydrodistillation. A strong chemical variability in essential oils depending on the origi ... | 2011 | 22164800 |
| Enzymatic activity of Microsporum canis and Trichophyton mentagrophytes from breeding rabbits with and without skin lesions. | Microsporum canis and Trichophyton mentagrophytes are zoophilic dermatophytes which can cause skin infections in animals and humans. The clinical expression of this infection strongly varies depending on host, fungal species as well as enzyme production. No comparative studies are available on the enzymatic activities of M. canis and T. mentagrophytes isolated from breeding rabbits. Thus, the aim of this work was to assess the capability of M. canis and T. mentagrophytes isolated from rabbits bo ... | 2012 | 22175244 |
| Decreasing Prevalence of Microsporum canis Infection in Korea: Through Analysis of 944 Cases (1993-2009) and Review of Our Previous Data (1975-1992). | Since 1957, Microsporum (M.) canis has been one of the common causative agents of dermatophytosis in Korea. We analyzed 944 patients infected with M. canis who attended outpatient clinic over a 17-year period (1993-2009). M. canis infections were diagnosed by mycological examinations, including direct microscopic examinations with 15% KOH and cultures on potato dextrose agar complemented with 0.5% chloramphenicol. Mycological examinations confirmed 164,903 cases of dermatophytosis, 944 (0.6%) of ... | 2011 | 22187358 |
| [fungi, pets and their owners]. | some parasitic or pathogen fungi for pet skin are possibly transmitted to humans in whom they are responsible for superficial mycozoonoses. cats, dogs and some small rodents are commonly involved. the lesions correspond to glabrous skin dermatophytoses and to microsporic tinea of the scalp. these disorders represent the vast majority of the prevalent mycozoonoses in wallonia. microsporum canis and trichophyton mentagrophytes are the two fungi that are commonly involved. | 2011 | 22216732 |
| chemical and biological diversity in fourteen selections of four ocimum species. | biomass, essential oil yield, essential oil composition diversity, and antibacterial and antifungal activities of 14 selections of 4 ocimum species [ocimum basilicum l. (selections: t1-t10), o. gratissimum l. (selections: t11-t12), o. tenuiflorum l.f., syn. o. sanctum l. (selection: t13) and o. kilimandscharicum baker ex. guerke (selection: t14)] were investigated. o. basilicum selections t9 (methyl chavicol: 87.0%) and t10 {(z)- and (e)-methyl cinnamate: 69.1%} produced higher biomass (67.8 and ... | 2011 | 22224293 |
| two pediatric cases of microsporum persicolor infection. | 2012 | 22250631 |