Publications

[kinetic study of the rabies virus in tissue culture using fluorescent antibodies and ultra-thin sections].		1963	14098096
the electron microscopy of rabies virus in cultures of chicken embryo tissues.		1963	14100615
reactivation of rabies virus in a guinea pig due to the stress of crowding.		1964	14103241
pathogenesis of rabies.	the authors have investigated the spread of fixed and street strains of rabies virus from the site of injection to the central nervous system and salivary glands in various animal species. the results indicate conclusively that rabies virus is ordinarily transmitted from the site of exposure to the central nervous system via the peripheral nerves but that other than nerve transmission may occur in young animals, in highly susceptible species or in animals whose resistance has been altered by tra ...	1963	14107754
[contribution to the problem of the dynamics of reproduction of fixed rabies virus in the brain of experimental animals].		1964	14109641
effect of ether on rabies virus.		1963	14109986
[the phenomenon of apathy in man and animals after the injection of viruses in very high doses. clinical data].		1963	14114227
viability of low-egg-passage, modified live-virus rabies vaccine following three and five years of storage.		1964	14118026
[on the pathogenicity of the virus of "rabies-like disease in polar animals" for man].		1963	14141359
studies on the low egg passage flury strain of modified live rabies virus produced in embryonating chicken eggs and tissue culture.		1964	14141518
rabies: a summary of recent contributions to the literature (july 1958-june 1963).		1964	14142004
immunofluorescence of non-cytopathic tissue culture adapted fixed rabies.		1964	14142420
a csee of rabies in england.		1964	14150893
observations on erythrocytic inclusion bodies from mice infected with rabies virus.		1964	14155799
ascites tumours from bhk.21 cells transformed in vitro by polyoma virus.		1964	14161203
antirabies antibody response in man to vaccine made from infected suckling-mouse brains.	antirabies vaccines produced from infected brains of adult mammals have always had the potentiality of causing post-vaccinal paralysis or allergic encephalitis in man. attempts in recent years either to remove the paralytic factor from brain-tissue vaccines or to use as the virus source infected tissue other than nervous tissue (e.g., chick embryos) have usually resulted in a substantial reduction of the specific antirabies potency.the authors' laboratory had previously developed a vaccine made ...	1964	14163964
[allergic encephalomyelitis and intermediate antigens of nerve tissues infected with viruses].		1964	14164801
properties of the nucleic acids from some herpes group viruses.		1964	14165337
[rabies].		1964	14175335
summary of rabies outbreak in maine.		1964	14180684
abortive rabies infection. i. experimental production in white mice and general discussion.		1964	14183397
studies with cultured brown adipose tissue. i. persistence of rabies virus in bat brown fat.		1964	14192763
studies with cultured brown adipose tissue. ii. influence of low temperature on rabies virus infection in bat brown fat.		1964	14192767
cytochemistry of inclusion bodies in tissue culture cells infected with rabies virus.		1964	14194600
[on viruses isolated from patients with encephalomyelitis and multiple sclerosis. i. pathogenic and antigenic properties of the isolated viruses].		1964	14195994
the development of fixed rabies virus in mouse brain.		1964	14202185
[infection of dog sub-maxillary gland cells cultivated in vitro by a fixed rabies virus].		1964	14206890
cultivation of rabies virus in human diploid cell strain wi-38.		1964	14218592
[development and diffusion of the rabies virus (flury hep strain) in embryonated egg and its multiplication on trypsinized cells of infected chick embryo (abstract)].		1964	14227592
[multiplication of rabies virus (flury hep strain) on hog kidney cells in continuous culture (abstract)].		1964	14227593
endosymbiotic relationship between animal viruses and host cells. a study of rabies virus in tissue culture.	re cultures infected with a fixed rabies virus were studied. the virus can propagate itself in these cells for an indefinite period of time without interfering with cell growth. the present study characterizes this truly endosymbiotic relationship. virus-specific antigen was detected in the cytoplasm of each cell by fluorescein-labeled antirabies serum but only 4 to 5 per cent of the cells released infectious virus. all cells undergoing division showed viral antigen throughout the mitotic proces ...	1964	14238928
electron microscopic studies of mouse brain infected with street rabies virus.		1964	14246008
propagation of rabies fixed virus in tissue culture.		1964	14247630
study of factors affecting the yield of rabies virus in tissue culture.		1964	14247631
tissue-culture rabies vaccine (flury lep) in dogs.		1965	14266931
advances in rabies research.		1964	14269511
paper electrophoresis study of sera of dogs immune to wild rabies virus.	three hyperimmune dogs were injected intramuscularly with canine wild rabies virus. the dogs showed no clinical evidence of rabies. intramuscular injection of the wild rabies virus in susceptible puppies induced fulminating disease and mortality in 14 to 16 days. investigation of the serum proteins of the hyperimmune dogs by a paper electrophoresis technique revealed conspicuous changes in the beta and gamma protein bands.	1965	14281077
simultaneous growth of rabies and canine distemper viruses in chick embryos.	rabies virus and canine distemper virus were grown simultaneously, and possibly symbiotically, in the same chick embryos. there seemed to be no adverse effect on either virus when cultured in such manner.bivalent vaccines for rabies and canine distemper were produced. the potencies and the virus titers of such vaccines were comparable to those of rabies vaccine and canine distemper vaccine produced separately.	1965	14290942
purification of fixed rabies virus.		1965	14297214
effects of cortisone on in vitro viral infection. i. inhibition of cytopathogenesis by polio, rabies and yellow fever viruses in human embryonic cells.		1965	14297833
accumulation of specific antigen and distribution of nucleic acids in sheep embryo kidney cells infected with street rabies virus as revealed by fluorescence microscopy.		1965	14303938
[fixed rabies virus and interferon].		1965	14305448
excretion of street rabies virus in the saliva of dogs.		1965	14313891
electrophoresis study of extracts of submaxillary salivary glands from naturally rabid dogs.	rabies virus in submaxillary salivary glands from naturally infected dogs was investigated by a paper electrophoresis technique, and the virus activity was quantitated by intracerebral titration in mice. extracts from these salivary glands were found to contain (a) 10(4) to 10(6) mouse icld (50) units of wild rabies seed and (b) a protein complex that migrated electrophoretically in the albumin band and more conspicuously in the beta and gamma bands of normal horse serum. the protein complex was ...	1965	14318538
laboratory investigation of arctic strains of rabies virus.		1965	14324666
[culture of rabies virus and its multiplication in bhk-21c-13 cells].		1965	14328265
[stabilization of fixed rabies virus].		1954	14349265
[considerations on the mechanism of action of the pasteur rabies virus-vaccine and on the mechanism of rabies immunity].		1954	14358007
early appearance of rabies virus in the blood of cave bats exposed by intraperitoneal injection.		1955	14365174
a report on research at mississippi state penitentiary.		1955	14369963
isolation of rabies virus from an insectivorous bat (tadarida mexicana) in california.		1955	14384888
studies by electron microscopy of a fixed (pasteur) rabies virus, a street rabies virus and the egg adapted flury strain of rabies.		1955	14386419
bentonite purification of certain viruses.		1955	14388338
human antirabies gamma globulin.	to obviate the foreign protein reactions experienced with the use of hyperimmune serum in rabies-exposed individuals, an attempt was made to produce a rabies antiserum of human origin.five doses of an inactivated rabies virus duck-egg vaccine were administered to 34 volunteers at 4-day intervals (i.e., on days 0, 4, 8, 12 and 16). an additional dose of chick-embryo attenuated virus vaccine-flury hep (high egg passage)-was given on the 46th day, followed by a final booster dose of duck-egg vaccin ...	1959	14403320
demonstration of rabies virus in tissue culture with fluorescent antibody technique.		1960	14404411
an indicator plaque-forming system for demonstration of interference by non-cytocidal strains of rabies virus.		1960	14404412
quantitative determination of the dissemination of flury rabies virus in the central nervous system of the guinea-pig after intramuscular inoculation in the hind leg.		1959	14405670
attempts to immunize guinea pigs with flury vaccine and subsequent challenge with fixed rabies virus.		1959	14405673
[histological featurs of rabies virus of bats in yugoslavia].		1959	14407028
[the arrest phenomenon in the white rat infected with fixed rabies virus and subjected to controlled hypothermia 48 hours before the onset of paralysis].		1959	14420102
[behavior of the arrest phenomenon in animals infected with fixed rabies virus and subjected to fractionated controlled hypothermia].		1959	14420104
[development of a method for the inactivation of anti-rabies vaccine with ultraviolet rays. i. effect of various conditions of action of ultraviolet rays on the infectious and immunogenic properties of fixed rabies virus].		1959	14433266
[note on the prolonged incubation or the latency of the rabies virus. study of the flury strain.--observation and discussion].		1959	14433379
studies on the local treatment of wounds for the prevention of rabies.	this paper reports on laboratory studies made in guinea-pigs on puncture wounds infected with fixed rabies virus and treated one hour later with various substances, the purpose being to review the experience of previous workers and to explore new approaches to the problem of local treatment of wounds inflicted by rabid animals.among the measures affording greater or lesser protection were: nitric acid cauterization; direct application of benzalkonium chloride to the wound or its infiltration, as ...	1962	14453773
[presence of specific inclusions in hamster kidney cells in tissue culture infected by fixed rabies virus (louis pasteur strain). kinetic study of the virus].		1961	14470606
electron microscopy of nerve cells infected with street rabies virus.		1962	14471291
studies on the pathogenesis of rabies.	in experiments on the pathogenesis of rabies, mice were challenged intracerebrally and intramuscularly with rabies virus and groups of the animals were sacrificed immediately and at various intervals after challenge and the virus content of several organs estimated. the influence of the site of injection on the duration of incubation and the effect of antirabies serum on the virus in the brain and in the skeletal muscle were also investigated.the results of these experiments indicate that shortl ...	1961	14498436
mccoy cell line as a possible model containing cd4+ receptors for the study of hiv-1 replication.	several studies have recently shown the use of recombinant rabies virus as potential vector-viral vaccine for hiv-1. the sequence homology between gp 120 and rabies virus glycoprotein has been reported. the mccoy cell line has therefore been used to show cd4+ or cd4+ like receptors. samples of hiv-1 were isolated, when plasma of hiv-1 positive patients was inoculated in the mccoy cell line. the virus infection was then studied during successive virus passages. the proteins released in the extra ...	2003	14502348
rabies in wildlife in latvia.	in the baltic states, lyssaviruses are often detected in wildlife and presumed to constitute an important public health hazard. in order to decrease rabies incidence and eradicate wildlife reservoirs, a national rabies eradication program has been in place. since 1970 a vaccination program in dogs and cats has been executed, and in 1991 oral vaccination of foxes was started. however, due to an insufficient budget, the latter was not done regularly and nationwide before 2000. now, the program in ...	2003	14511581
oral vaccination of mice with adenoviral vectors is not impaired by preexisting immunity to the vaccine carrier.	adenovirus vectors with e1 deleted of the human serotype 5 (adhu5) and the chimpanzee serotype 68 (adc68) expressing the glycoprotein of the evelyn rokiniki abelseth strain of rabies virus were tested upon oral application for induction of systemic and mucosal transgene product-specific antibody responses in mice. both vectors induced systemic and mucosal antibodies to rabies virus, including virus-neutralizing antibodies and protection against a severe intracerebral challenge with a mouse-adapt ...	2003	14512528
functional human immunodeficiency virus type 1 (hiv-1) gag-pol or hiv-1 gag-pol and env expressed from a single rhabdovirus-based vaccine vector genome.	recombinant rabies virus (rv) vaccine strain-based vectors have been successfully developed as vaccines against other viral diseases (j. p. mcgettigan et al., j. virol. 75:4430-4434, 2001; mcgettigan et al., j. virol. 75:8724-8732, 2001; c. a. siler et al., virology 292:24-34, 2002), and safety concerns have recently been addressed (mcgettigan et al., j. virol. 77:237-244, 2003). however, size limitations of the vectors may restrict their use for development of vaccine applications that require ...	2003	14512539
sequence analysis of rabies virus in humans exhibiting encephalitic or paralytic rabies.	two distinct clinical patterns, encephalitic (furious) and paralytic (dumb), have been recognized in human rabies. it has been postulated that different rabies virus variants associated with particular vectors may be responsible for these different clinical manifestations. analysis of the glycoprotein (g), nucleoprotein (n), and phosphoprotein (p) genes of rabies viruses from 2 human cases of encephalitic rabies and from 2 human cases of paralytic rabies demonstrated only minor nucleotide differ ...	2003	14513414
cell-type-specific gene delivery into neuronal cells in vitro and in vivo.	the avian retroviruses reticuloendotheliosis virus strain a (rev-a) and spleen necrosis virus (snv) are not naturally infectious in human cells. however, rev-a-derived viral vectors efficiently infect human cells when they are pseudotyped with envelope proteins displaying targeting ligands specific for human cell-surface receptors. here we report that vectors containing the gag region of rev-a and pol of snv can be pseudotyped with the envelope protein of vesicular stomatitis virus (vsv) and the ...	2003	14517061
skunk and raccoon rabies in the eastern united states: temporal and spatial analysis.	since 1981, an epizootic of raccoon rabies has spread throughout the eastern united states. a concomitant increase in reported rabies cases in skunks has raised concerns that an independent maintenance cycle of rabies virus in skunks could become established, affecting current strategies of wildlife rabies control programs. rabies surveillance data from 1981 through 2000 obtained from the health departments of 11 eastern states were used to analyze temporal and spatial characteristics of rabies ...	2003	14519253
improved recovery of rabies virus from cloned cdna using a vaccinia virus-free reverse genetics system.	to improve efficiency of recovery of rabies virus from cloned cdna, we established a bhk cell clone that stably expresses t7 rna polymerase, which we named bhk/t7-9. we also constructed new helper plasmids for expression of nucleoprotein and rna polymerase of the rc-hl strain using the ptm1 plasmid vector, which makes the t7 rna polymerase-transcripts from the plasmid cap-independent for translation. after co-transfection of these helper plasmids and the previously constructed full-length genome ...	2003	14524622
a system of protein target sequences for anti-rna-viral chemotherapy by a vitamin b6-derived zinc-chelating trioxa-adamantane-triol.	the synthesis of the structurally unusual heterotricyclic compound 1-[3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]-2,8,9-trioxaadamantane-3,5,7-triol (trivially named bananin, bn) from pyridoxylidenephloroglucinol and a theoretical prospect on possible biological activities of bn are presented in this report. pyridoxylidenephloroglucinol is synthesized by knoevenagel condensation of the vitamin b6 aldehyde pyridoxal with phloroglucinol. pyridoxylidenephloroglucinol rearranges to light-yello ...	2003	14527557
mucosally delivered e1-deleted adenoviral vaccine carriers induce transgene product-specific antibody responses in neonatal mice.	e1-deleted adenoviral vectors of the human serotype 5 (adhu5) and the chimpanzee serotype 68 (adc68) expressing the rabies virus glycoprotein (rab.gp) were tested for induction of transgene product-specific abs upon intranasal or oral immunization of newborn mice. both vectors induced abs to rabies virus that could be detected in serum and from mucosal secretions. serum rabies virus neutralizing ab titers sufficed to protect neonatally vaccinated mice against a subsequent challenge with rabies v ...	2003	14530353
high level of bcl-2 counteracts apoptosis mediated by a live rabies virus vaccine strain and induces long-term infection.	we report here that rabies virus strains, currently used to immunize wildlife against rabies, induce not only caspase-dependent apoptosis in the human lymphoblastoid jurkat t cell line (jurkat-vect), but also a caspase-independent pathway involving the apoptosis-inducing factor (aif). in contrast, a strain of neurotropic rv that does not induce apoptosis did not activate caspases or induce aif translocation. bcl-2 overproduction in jurkat t cells (jurkat-bcl-2) abolished both pathways. era infec ...	2003	14554083
nasal trigeminal inputs release the a5 inhibition received by the respiratory rhythm generator of the mouse neonate.	experiments were performed on neonatal mice to analyze why, in vitro, the respiratory rhythm generator (rrg) was silent and how it could be activated. we demonstrated that in vitro the rrg in intact brain stems is silenced by a powerful inhibition arising from the pontine a5 neurons through medullary alpha(2) adrenoceptors and that in vivo nasal trigeminal inputs facilitate the rrg as nasal continuous positive airway pressure increases the breathing frequency, whereas nasal occlusion and nasal a ...	2004	14561692
[human cases of hydrophobia in the russian federation].	the analysis of 29 human cases of hydrophobia registered in the russian federation in 2000-2001 is presented. dogs appeared to be the main infection source (50% of cases). an increased proportion of cats (17.3%) in the spread of the disease was noted. among wild animals, the leading role of foxes in the spread of rabies virus was determined. a number of serious drawbacks in the organization of antirable service to the population, in particular, insufficient qualification of medical personnel, a ...	2003	14565138
population monitoring in support of a rabies vaccination program for skunks in arizona.	three population monitoring methods were evaluated in support of a trap/vaccinate/release program for controlling a bat variant of rabies virus in skunks (mephitis mephitis) in flagstaff, arizona (usa). skunks were the primary species targeted for population monitoring during the program, but feral cats were also monitored as they represented an abundant secondary vector species capable of rabies transmission. skunks were vaccinated and released, except for a subset tested for rabies. all captur ...	2003	14567243
recommendations of a national working group on prevention and control of rabies in the united states. article iii: rabies in wildlife. national working group on rabies prevention and control.		1999	14575027
rabies dna vaccine in the horse: strategies to improve serological responses.	in order for dna vaccines to become a practical alternative to conventional vaccines their ability to induce antibody responses in large mammals needs to be improved. we used dna vaccination against rabies in the horse as a model to test the potential of two different strategies to enhance antibody responses in a large mammalian species. the administration of the dna vaccine in the presence of aluminum phosphate improved both the onset and the intensity of serological responses but was not poten ...	2003	14575772
dissociation of rabies virus matrix protein functions in regulation of viral rna synthesis and virus assembly.	recently, we have shown that the rabies virus (rv) matrix (m) protein regulates the balance of virus rna synthesis by shifting synthesis activity from transcription to replication (s. finke, r. mueller-waldeck, and k. k. conzelmann, j. gen. virol. 84:1613-1621, 2003). here we describe the identification of an m residue critical for regulation of rv rna synthesis. by analyzing the phenotype of heterotypic rv m proteins with respect to rna synthesis of rv sad l16, we identified the m proteins of t ...	2003	14581544
safe and easy monitoring of anti-rabies antibody in dogs using his-tagged recombinant n-protein.	the virus neutralization (vn) test is a reliable indicator of adequate vaccination in animals. however, the vn test is tedious and complicated to perform. enzyme-linked immunosorbent assay (elisa), though rapid and simple compared to the vn test, is complicated and hazardous during preparation of the viral antigen. in an effort to overcome the disadvantage of elisa, the recombinant his-tagged nucleoprotein (his-rnp) expressed in escherichia coli was used as a safe antigen for elisa (i.e., live v ...	2003	14583639
does contact with urine and blood from a rabid dog represent a rabies risk?		2003	14583881
monoclonal antibody #3-9-16 recognizes one of the two isoforms of rabies virus matrix protein that exposes its n-terminus on the virion surface.	we investigated behaviors of the rabies virus matrix (m) protein using a monoclonal antibody (mab), #3-9-16, that recognized a linear epitope located at the n-terminus of the protein. based on the reactivity with this mab, m proteins could be divided into at least two isoforms; an ordinary major form (malpha) whose 3-9-16 epitope is hidden, and an n-terminal-exposed epitope-positive form (mbeta). the mbeta protein accounted for about 25-30% of the total m proteins in the virion, while its conten ...	2003	14584611
genetic characterization of rabies field isolates from thailand.	we sequenced 512 nucleotides in two variable regions of the n gene of 23 rabies isolates from the northeastern part of thailand by direct sequencing of pcr-amplified products. the sequencing data revealed two new lineages in these rabies isolates. based on the results of this study together with the findings of our earlier study, the rabies isolates in thailand were divided into two genogroups, designated as t1 and t2, which were predominantly localized in the northern and northeastern areas, re ...	2003	14584612
another interpretation of ferret's reaction to vaccination.		2003	14584736
apoptosis and rabies virus neuroinvasion.	rabies virus (rv) causes a non-lytic infection of neurons leading to a fatal myeloencephalitis in mammals including humans. by comparing the infection of the nervous system of mice by a highly pathogenic neuroinvasive strain of rv (cvs) and by a strain of attenuated pathogenicity (pv) with restricted brain invasion, we showed that rv neuroinvasiveness results of three factors: not only neurotropic rv avoids induced neuron cell death but also "protective" t cells that migrate into the infected ne ...	2003	14585545
toxicity and antiviral activity of cinnabarin obtained from pycnoporus sanguineus (fr.) murr.	this work describes the cytopathic effect on cells, cytotoxic action on mice, and antiviral activity of cinnabarin. this substance had no effect on mouse neuroblastoma cells (na cell, atcc clone c-1300) at a concentration of 0.31 mg/ml, it was not able to cause toxic effects in mice at concentrations of 1000 mg/kg, and reduced by four times the titers of the rabies virus at concentrations of 0.31 mg/ml.	2003	14595589
isothermal amplification of rabies virus gene.	a sensitive and specific in situ amplification technique is needed to elucidate the dynamics of rabies virus in the body during the long incubation period after infection. to overcome the disadvantage of using the traditional reverse transcription (rt)-pcr in in situ studies, an isothermal nucleic acid sequence-based amplification (nasba) technique was developed for detection of the rabies virus gene. the nasba technique involves the use of 4 enzymatic activities to produce multiple rna copies o ...	2003	14600342
characterization of rabies virus isolates in bolivia.	in latin america, rabies is still an important public health problem. canine rabies, and wild animal rabies, especially transmitted by hematofagous and insectivorous bats, has become an emerging problem in the countries of this region. we received 363 samples with a laboratory-confirmed rabies diagnosis from bolivia during l997-2001. from these, we could obtain 222 rabies virus isolates by intra-cerebral inoculation in mice. by antigenic characterization we could identify 147 isolates as variant ...	2003	14602205
further characterization of a cd99-related 21-kda transmembrane protein (vap21) expressed in syrian hamster cells and its possible involvement in vesicular stomatitis virus production.	the vap21, a cd99-related 21-kda transmembrane protein, was first detected in the enveloped virions that were grown in a syrian hamster-derived cell line, bhk-21 (sagara et al., 1997; yamamoto et al., 1999). we further tried to elucidate the nature and properties of vap21. the vap21 was detected in various organs of the syrian hamster as well as in the syrian hamster-derived cell lines (bhk-21 and hmlu-1). we could not detect the vap21 antigen in other cell lines derived from other animal specie ...	2003	14605441
chemokines and trance as genetic adjuvants for a dna vaccine to rabies virus.	an adaptive immune response is initiated by mature dendritic cells presenting processed antigen to nai;ve t cells. assuming that the magnitude of the immune response is influenced by the number and type of antigen-presenting dendritic cells and by the duration of antigen presentation, we tested if chemokines that bind to receptors expressed on immature dendritic cells or trance, a survival factor for mature dendritic cells, can serve as adjuvants. none of the immunomodulaters given as genetic ad ...	2003	14609576
covalently linked human immunodeficiency virus type 1 gp120/gp41 is stably anchored in rhabdovirus particles and exposes critical neutralizing epitopes.	rabies virus (rv) vaccine strain-based vectors show significant promise as potential live-attenuated vaccines against human immunodeficiency virus type 1 (hiv-1). here we describe a new rv construct that will also likely have applications as a live-attenuated or killed-particle immunogen. we have created a rv containing a chimeric hiv-1 env protein, which contains introduced cysteine residues that give rise to an intermolecular disulfide bridge between gp120 and the ectodomain of gp41. this cova ...	2003	14610200
first human death associated with raccoon rabies--virginia, 2003.	rabies is an acute, progressive, incurable viral encephalitis, caused by the bite of an infected animal. in march 2003, a previously healthy man aged 25 years from northern virginia died from a diagnosed illness of meningoencephalitis of unknown etiology after a 3-week illness. histopathologic review of central nervous system tissues at cdc revealed viral inclusions suggestive of negri bodies, and subsequent tests confirmed a diagnosis of rabies. genetic sequencing identified a rabies virus vari ...	2003	14614408
post-exposure therapy in mice against experimental rabies: a single injection of dna vaccine is as effective as five injections of cell culture-derived vaccine.	two rabies post-exposure therapies were comparatively evaluated: balb/c mice were challenged at day 0 with rabies virus and then received either a single dose of rabies dna vaccine administered at day 0, or five doses of cell culture-derived rabies vaccine administered at days 0, 3, 7, 15 and 28. both regimens, rapidly triggered protective levels of neutralizing antibodies against rabies virus in vaccinated mice. in addition, one injection of dna vaccine protected 53% of the challenged mice, com ...	2003	14615144
efficacy of rabies immunoglobulins in an experimental post-exposure prophylaxis rodent model.	in a recently published syrian hamster animal challenge study [vaccine 19 (2001) 2273], a highly purified, heat-treated equine rabies immunoglobulin (perig ht, favirab) did not elicit satisfactory protection. the efficacies of this batch, a second stage perig ht batch and reference rig preparations (imorab, imogam rage pasteurised, berna antiserum) were compared in mice challenged with either ariana canine field strain or cvs strain. survival rates against ariana challenge with the second perig ...	2003	14615152
comparative evaluation of immunogenicity, reactogenecity and safety of purified chick embryo cell rabies vaccine and neural tissue rabies vaccine.	1. to compare the protective antibody titres on day 14, 30 and 90 after giving intramuscular (im) injections of pcecv and subcutaneous injections of nervous tissue vaccine. 2. to compare the immunogenicity and safety of pcecv and ntv.	2003	14621031