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multiple units of transcription in phage lambda. 19665237196
in vitro repression of phage lambda dna transcription by a partially purified repressor from lysogenic cells. 19685238651
regulation of bacteriophage lambda dna replication. 19675242210
replication of bacteriophage dna, ii. structure of replicating dna of phage lambda. 19685243927
the operators controlled by the lambda phage repressor. 19685244737
studies of the messenger rna of bacteriophage lambda, i. various species synthesized early after induction of the prophage. 19685246538
the general recombination system of bacteriophage lambda. 19685254579
site-specific recombination in bacteriophage lambda. 19685254580
integration, excision, and transducing particle genesis by bacteriophage lambda. 19685254581
the integration and excision of the bacteriophage lambda genome. 19685254582
the regulation and mechanism of dna synthesis in bacteriophage lambda. 19685254585
deoxyribonuclease iv: a new exonuclease from mammalian tissues.an exonuclease which specifically degrades double-standard dna has been isolated from rabbit tissues. the enzyme has an approximate molecular weight of 42,000, requires a divalent metal ion as cofactor, and attacks dna at the 5'-terminal ends, thereby liberating 5'-mononucleotides. it degrades several synthetic polydeoxynucleotides of single repeating base sequences more rapidly than dna from natural sources. the specificity of this mammalian enzyme resembles that of several microbial enzymes (p ...19695256235
on the transfer of information from old to new chains of dna duplexes in phage lambda: destruction of heterozygotes.the watson-crick model for dna duplex duplication proposes that the two parental chains separate and that each directs the synthesis of a complementary chain with which it is found associated after the duplication act. previous experiments have left unchallenged alternative models which propose that in any single act of duplication only one of the two parental chains provides information for the synthesis of both new chains. the models are operationally ditinguishable since the former demands th ...19705263770
regulation of repressor expression in lambda.a new gene in bacteriophage lambda is described. the product of this gene cro prevents expression of immunity and regulates the expression of those genes to the left of the immunity region. cro(-) mutants have been isolated and characterized.19705269249
control of transcription of the repressor gene in bacteriophage lambda.the rate of transcription of the structural gene for repressor (ci gene) in bacteriophage lambda is controlled by the amount of active repressor in the cell. when the (reversibly) thermolabile repressor in a bacterium lysogenic for lambdaci(857) is inactivated by heat, the rate of repressor gene transcription immediately falls. if the repressor is renatured, synthesis of repressor messenger is immediately restored to a high rate. control by the repressor of the rate of transcription of its own s ...19705274442
mutation and recombination of bacteriophage lambda: effect of ultraviolet radiation.defects in the bacterial recb or recc or phage red or int gene did not impair ultraviolet light-induced clear mutations of lambda phage. clear mutants of ci and cii genes were not enriched among reca-promoted uv-induced recombinants between the n and o genes which closely encompass the c genes. no correlation was observed between uv-induced mutation and genetic recombination.19705276152
dna of vegetative bacteriophage lambda. vi. electron microscopic studies of replicating lambda dna.electron micrographs of replicating lambda dna molecules, during the period of progeny-particle dna formation, show single-tailed circular structures. the tails are, predominantly, shorter than one viral genome.19715276280
in vitro repression of rna synthesis by purified lambda phage repressor. 19715279042
fate of bacteriophage lambda dna after adsorption by haemophilus influenzae. 19715314514
the formation of superinfection-double lysogens of phage lambda in escherichia coli k-12. 19655318339
nuclease activity in defective lysogens of phage lambda. 19645319710
effect of glucose on the capacity of escherichia coli to be infected by a virulent lamba bacteriophage.howes, william v. (massachusetts institute of technology, cambridge). effect of glucose on the capacity of escherichia coli to be infected by a virulent lambda bacteriophage. j. bacteriol. 90:1183-1193. 1965.-a substrate-dependent phenotypic resistance to phage lambda(vir) was observed among cells of escherichia coli w3350 and c600 grown aerobically on glucose. similar cells grown on glycerol were sensitive. when cells of w3350 grown on glycerol were transferred to glucose, the rate of appearanc ...19655321475
the steric effect in lysogenization by bacteriophage lambda. i. lysogenization of a partially diploid strain of escherichia coli k-12. 19655321952
the steric effect in lysogenization by bacteriophage lambda. ii. chromosomal attachment of the b2 mutant. 19655321953
kinetics of bacteriophage lambda deoxyribonucleic acid infection of escherichia coli.barnhart, benjamin j. (los alamos scientific laboratory, university of california, los alamos, n.m.). kinetics of bacteriophage lambda deoxyribonucleic acid infection of escherichia coli. j. bacteriol. 90:1617-1623. 1965.-the kinetics of escherichia coli k-12 infection by phage lambda deoxyribonucleic acid (dna) were determined. an initial lag of 55 to 80 sec was found to be the time required for infecting dna to become deoxyribonuclease-insensitive at 33 c. when cell-dna interactions were stopp ...19655322721
intracellular state of the chromosome of bacteriophage lambda. i. the eclipse of infectivity of the bacteriophage dna. 19655323478
methylated bases in the host-modified deoxyribonucleic acid of escherichia coli and bacteriophage lambda.gough, michael (brown university, providence, r.i.), and seymour lederberg. methylated bases in the host-modified deoxyribonucleic acid of escherichia coli and bacteriophage lambda. j. bacteriol. 91:1460-1468. 1966.-the deoxyribonucleic acid (dna) from strains of escherichia coli and phage lambda was examined to determine whether the types or amounts of methionine-derived methylated bases present correlated with the host-specific modification of that dna. the dna of strain c600 (which has k-12 m ...19665326110
intracellular forms of lambda deoxyribonucleic acid in escherichia coli infected with clear or virulent mutants of bacteriophage lambda.weissbach, arthur (national institutes of health, bethesda, md.), allan lipton, and arnold lisio. intracellular forms of lambda deoxyribonucleic acid in escherichia coli infected with clear or virulent mutants of bacteriophage lambda. j. bacteriol. 91:1489-1493. 1966.-infection of either the sensitive or lysogenic strain of escherichia coli k-112s by lambda(+) leads to the formation of a new phage deoxyribonucleic acid (dna) species having the properties of a twisted circular dna duplex. this ne ...19665326113
inhibition of escherichia coli and bacteriophage lambda messenger rna synthesis by t4. 19655326385
the steric effect in lysogenization by bacteriophage lambda. 3. superinfection of monolysogenic derivatives of a strain diploid for the prophage attachment site. 19665328228
acridine orange- and methylene blue-sensitized induction of escherichia coli lysogenic for phage lambda. 19665331915
5-methylcytosine in the host-modified dna of escherichia coli and phage lambda. 19665335758
formation of bacteriophage lambda infective particles from lambda dna in the presence of the crude extract of escherichia coli k12 s. 19675336882
studies of heat-inducible lambda phage. iv. conversion of host phenotype by a defective prophage. 19675337608
some properties of dna from phage-infected bacteria.replicating t5 or lambda phage dna has been labeled by adding tritiated thymidine for short periods to cultures of phage-infected escherichia coli before isolation of intracellular dna. two procedures are described for separating t5 replicating dna from dna of intracellular phage particles. both t5 and lambda replicating dna had the same bouyant density in cesium chloride as dna from phage particles but sedimented faster when centrifuged in sucrose density gradients. the fast sedimentation did n ...19665338559
studies of heat-inducible lambda-phage. 3. mutations in cistron n affecting heat induction. 19665339322
effects of lambda-phage infection on bacterial synthesis. 19675339797
absortive lysogenization of bacteriophage lambda b2 and residual immunity of non-lysogenic segregants. 19675340186
effect of ultraviolet irradiation on bacteriophage lambda immunity. 19675340187
inhibition of growth of rii mutants of bacteriophage t4 by immunity substance of bacteriophage lambda. 19675340188
transcription of complementary strands of phage lambda-dna in vivo and in vitro. 19675340634
mapping of integration and excision crossovers in superinfection double lysogens for phage lambda in escherichia coli. 19675341475
in vitro polymerization of bacteriophage lambda tails. 19695344290
dna replication in head mutants of bacteriophage lambda. 19695357220
insertion of phage mu. 1 within prophage lambda. a new approach for studying the control of the late functions in bacteriophage lambda. 19695370121
the biosynthesis of phage lambda dna. 19695372867
induction and multiplication of lambda-phage. 3. the effect of hydroxyurea on heat induction. 19695377768
gene expression in bacteriophage lambda. i. the kinetics of the requirement for n gene product. 19705411187
on the function of the n cistron in phage lambda. 19705411191
location of the phage lambda gene responsible for turning off lambda-exonuclease synthesis. 19705411194
lambda phage mutants insensitive to temperature-sensitive repressor. ii. genetic character of lambda vir c mutant. 19705415250
a site essential for expression of all late genes in bacteriophage lambda. 19705418171
suppression of a mutant phenotype concerning head formation of bacteriophage lambda by the product of the lambda repressor gene. 19705424817
functional analysis of early defective mutants of coliphage lambda. 19705432279
on the control of lysogeny in phage lambda. 19705437788
[the mechanism of t2 and lambda phage dna molecule double break formation when irradiated in solution and the radiobiologic role of these breaks]. 19705451502
effect of mutations in the c2 and c3 genes of bacteriophage lambda on macromolecular synthesis in infected cells. 19705453348
mutator gene action and the replication of bacteriophage lambda dna. 19705453351
[lambda-phage; introduction to the special issue on lambda phage]. 19705465674
mutations of coliphage lambda affecting the expression of replicative functions o and p. 19705475574
nucleotide clusters in deoxyribonucleic acids. vi. the pyrimidine oligonucleotides of strands r and l of bacteriophage lambda dna. 19705485908
controls of rightward transcription in coliphage lambda. 19705492022
gene expression in bacteriophage lambda. ii. regulation of rna synthesis in vivo by the n protein. 19705493281
[density gradient ultracentrifugation of absolute defective lambda phage mutants]. 19705503575
interruption of dna injection by x-irradiation of phage lambda. 19715543269
lack of polarity of dna injection by escherichia coli phage lambda. 19715543271
the fine structures in melting curves of deoxyribonucleic acids of bacteriophage lambda. i. 19715543649
phenomenological theory of repair kinetics of ultraviolet irradiated lambda phage. 19715543830
uv-reactivation of bacteriophage lambda in excision repair-deficient hosts: independence of red functions and attachment regions. 19715543836
deletion mutants of bacteriophage lambda. ii. genetic properties of att-defective mutants. 19715551395
deletion mutants of bacteriophage lambda. 3. physical structure of att-phi. 19715551396
the role of exonuclease and beta protein of phage lambda in genetic recombination. 3. binding to deoxyribonucleic acid. 19715553408
cold-sensitive mutants of bacteriophage lambda. 19715556293
formation of concatemers of lambda phage dna in a recombination-deficient system. 19715563932
[a simple method of purifying bacteriophage lambda on wide pore glass]. 19715567351
[transducing capacity of lambda-phage during disordered synthesis of the host bacterium cell wall]. 19715571364
heat-inducible lambda phage. v. induction of prophages with mutations in genes o, p, and r. 19675583727
deletions and functions of the center of the phi80 -lambda phage genome. evidence for a phage function promoting genetic recombination. 19675584569
isolation and characterization of new sus (amber) mutants of bacteriophage lambda. 19675591286
[on a method of comparing the radiosensitivity of the dna of the "operating" and "programming" structures of the genome of lambda phage following the indirect effect of radiation]. 19675616248
protein components of bacteriophages lambda and lambda virulent.parallel studies have been made of the protein coats of the temperate bacteriophage lambda and of a deletion mutant, lambda virulent. a new method for preparing ghosts of both phages by the action of cu(++) is described. protein ghosts of both phages can be dissolved in citrate at ph values below 3, more rapidly in the presence of 8 m urea. both phages yielded three apparently identical protein components which can be separated by thin-layer gel filtration and thin-layer gel electrophoresis. the ...19675621486
integration-negative mutants of bacteriophage lambda. 19685637199
mutations in bacteriophage lambda affecting particle morphogenesis. 19685652675
studies on the genetics of biotin-transducing, defective variants of bacteriophage lambda. 19685669988
induction and multiplication of lambda-phage. ii. the effect of valine and leucine. 19685679785
disruption of t-even bacteriophages by dimethyl sulfoxide.dimethyl sulfoxide (dmso) disrupted t-even bacteriophages as well as lambda bacteriophage. the component substructures of t2l, t4b01, or t6, in particular heads, were readily isolated after treatment with 67% dmso (v/v). in contrast, concentrations of dmso above 50% not only separated heads from tails of bacteriophage lambda but led to degradation of the lambda heads. examination of the isolated free heads of t-even bacteriophage indicated that a distinct neck substructure was attached to one ap ...19685697471
gene orientation in bacteriophage lambda as determined from the genetic activities of heteroduplex dna formed in vitro. 19685700418
genetics of the left arm of the chromosome of bacteriophage lambda. 19685705826
genetic transcription in bacteriophage lambda: studies of lambda m rna synthesis in vivo. 19685719216
evidence for a new endonuclease synthesized by lambda bacteriophage.infection of nonlysogenic escherichia coli cr34(s) (thy(-)) with bacteriophage lambda c(i)857 resulted in the formation of twisted circular double-stranded phage deoxyribonucleic acid (dna; species i). when such infected bacteria were incubated in the absence of thymine, there was a significant decrease in the amount of species i dna after 60 min of incubation. a similar loss of species i lambda dna during incubation in a thymine-deficient medium was also observed after infection of the endonucl ...19685723713
[elimination of t4rii by c-mutants of the lambda phage]. 19685745532
integrative recombination function of bacteriophage lambda: evidence for a site-specific recombination enzyme. 19685760457
recombination in bacteriophage lambda. i. mutants deficient in general recombination. 19685760458
recombination in bacteriophage lambda. ii. site-specific recombination promoted by the integration system. 19685760459
orientation and control of transcription in e. coli phage lambda. 19695765054
mapping of deletions and substitutions in heteroduplex dna molecules of bacteriophage lambda by electron microscopy.electron microscopy of heteroduplex dna molecules, composed of one strand of escherichia coli phage lambda(+) dna annealed to the complementary dna strand of a lambda deletion or substitution mutant, permits visualization, as well as precise measurements and mapping, of the unpaired single-stranded regions of nonhomology in the otherwise double-stranded molecules. in the lambdab2 mutant, the central segment (13 percent) of the lambda(+) dna molecule is shown to be deleted. in the hybrid phages l ...19695765116
genetic mapping of an endonuclease synthesized by bacteriophage lambda. 19695799035
patterns of convergent and overlapping transcription within the b2 region of coliphage lambda. 19695803945
the effect of proflavine on the vegetative reproduction of bacteriophage lambda. 19695804680
lambda phage mutants insensitive to temperature-sensitive repressor. i. isolation and genetic analysis of weak-virulent mutants. 19695804682
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