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inactivation of rous sarcoma virus on contact with n-ethyl isatin -thiosemicarbazone. 19714328024
histochemical studies of chick embryo chorio-allantoic membranes infected with vaccinia and smallpox viruses. i. glycogen, glycoproteins and mucopolysaccharides. 19714328237
[activity of the disinfectants gevisol and quartasept on several pathogenic viruses]. 19714328644
host-cell repair of vaccinia virus and of double stranded rna of encephalomyocarditis virus. 19714328801
vaccine production in human diploid cell strains. 19714329326
varicella zoster virus: interferon production and comparative interferon sensitivity in human cell cultures. 19714329449
[pathological immune phenomena in virus diseases]. 19704329530
[experiments on the challenge of the antivaccinial transfer immunity of cell cultures by infection with variola virus. (evaluation of the antivariola potency of smallpox vaccines)]. 19684329545
factors affecting plaque assay of animal viruses--with special reference to vesicular stomatitis and vaccinia virus. 19714329547
antiviral activity of novobiocin. 19704329711
[the immunological adjuvant effect of viruses on the production of antibodies against host cell antigens]. 19714330255
removal of contaminating protein from high titre virus suspensions to be used in the production of antisera for immunofluorescence. 19714330259
system of double infection between vaccinia virus and mengovirus.when l cells are simultaneously infected with vaccinia virus and mengovirus, double interference in the replication of both viruses is observed. superinfection of vaccinia virus-infected cells by mengovirus during the first 5 hr of infection reduces vaccinia virus yields to between 1 and 3% of controls. the yields of mengovirus are reduced to between 1 and 16% of controls, depending upon the time of superinfection. the replication of vaccinia deoxyribonucleic acid is not inhibited by mengovirus; ...19714330362
biogenesis of poxviruses: identification of four enzyme activities within purified yaba tumor virus. 19714331108
formation of small plaques by herpes viruses irradiated with ultraviolet light. 19714331109
[reproduction of dna viruses]. 19714331673
increase in preexisting cellular antigen-combining groups at different times after infection with different viruses.during the course of experiments designed to determine whether infection of normal cells with certain strains of herpesvirus hominis (hsv) gives rise to a specific neoantigen, presumably characteristic for human malignant cells ("hela g"), it was found that the seeming appearance of such a new antigen actually represents only an increase in concentration of previously existing normal antigen groups. the complement fixation tests for this antigen were carried out with antibody prepared by mckenna ...19704331719
characteristics of a new poxvirus isolated from indian buffaloes. 19714331778
antiviral activity of tobacco leaf on encephalomyocarditis (emc) virus infection. 19714331947
[pathogenesis of virus diseases]. 19704331981
[could pox vaccination be improved? studies on oral pox vaccination]. 19704331986
use of disposable micro tissue culture plates for antiviral and interferon induction studies.a reproducible test system requiring small amounts of test compound was developed for evaluating antiviral and interferon-inducing activity. in the antiviral experiments, kb cells were grown in disposable polystyrene microplates covered with a standard domestic plastic wrap. viruses used in the system were types 1 and 2 herpes simplex virus, vaccinia virus, type 3 adenovirus, myxoma virus, pseudorabies virus, type 3 parainfluenza virus, types 1a and 13 rhinovirus, vesicular stomatitis virus, cox ...19714332040
antibody in wild animal (african) sera to human and simian viruses. 19714332151
the nature of the immune state produced by inactivated vaccinia virus in rabbits. 19714332354
[the antifungal effect of the sodium salt of levorin in cell cultures]. 19714332928
biogenesis of vaccinia: effect of rifampicin on transcription. 19714332970
[macromolecular virostatic substances and their interferon inducing activity]. 19714333130
7-deazanebularin. metabolism in cultures of mouse fibroblasts and incorporation into cellular and viral nucleic acids. 19724333510
antiviral agents. 5h-as-triazino(5,6-b) indoles. 19724333824
attempt to identify the agent for creutzfeldt-jakob disease by cf antibody relationship to known viruses. 19724333969
growth of newcastle disease and herpes virus and interferon production in a monkey-mouse hybrid line. 19724334778
[specific antigens in virus-infected cells]. 19714334954
relationship of physical particles of yaba virus to infectivity as assayed by an improved focus-counting method. 19714335007
effect of chloroquine on the growth of animal viruses. 19724335025
in vitro stimulation of sensitized lymphocytes by herpes simplex virus and vaccinia virus.splenic lymphocytes from rabbits immunized with herpes simplex virus (hsv) were incubated in vitro with ultraviolet light-inactivated hsv, and the degree of lymphocyte transformation was determined by measurement of the incorporation of [(3)h]thymidine into acid-insoluble material. lymphocytes from immunized rabbits were stimulated as much as 30-fold, whereas lymphocytes from control rabbits were unaffected. lymphocyte sensitization occurred within 3 days after immunization; sensitized lymphocyt ...19724335071
[inactivation of viruses by sewage protozoa]. 19704335490
cell-dependent differences in the production of infectious herpes simplex virus at a supraoptimal temperature.the replication of herpes simplex virus (hsv) was compared in rabbit and hamster cells at optimal and supraoptimal temperatures. replication occurred in cells of either species at 33 c, but the total infectious virus yield was routinely about 10-fold greater in rabbit cells than in hamster cells. at 39 c, this difference was exaggerated to greater than 100,000-fold. whereas infectious virus was produced and plaques formed in rabbit kidney cell monolayers at the higher temperature, neither develo ...19724335516
establishment, viral susceptibility and biological characteristics of a swine kidney cell line sk-6. 19724336054
failure of the scrapie agent to replicate in l5178y mouse leukaemic cells. 19724336055
general characteristics of enhanced plague formation by poliovirus in poxvirus-infected cells. 19724336518
poly i:c, an inducer of interferon and interference against virus infections. 19724336643
inhibition of msv viral function by rifampicin derivatives. 19724336644
evaluation of gentamicin for use in virology and tissue culture.data are presented comparing gentamicin to penicillin and streptomycin (pen-strep) in tissue culture medium with respect to a number of parameters associated with virology and tissue culture. unlike pen-strep, gentamicin was stable at ph 2 to 10 for 15 days at 37 c in tissue culture medium, and its activity was unaffected by the presence of serum. moreover, it was stable to autoclaving. twenty cell types replicated normally at the suggested concentration of 50 mug/ml, and all cells were unaffect ...19724336661
monkeypox virus: responses of infection in chick embryos. 19724336826
macrophage migration inhibition test: experimental and clinical studies. 19714336949
mechanism of the antiviral activity resulting from sequential administration of complementary homopolyribonucleotides to cell cultures.the antiviral activity of the double-stranded complex poly(ri) . poly(rc) in cell culture was restored or even surpassed if the constituent homopolymers were administered separately. poly(ri) primed the cells for the antiviral activity of poly(rc) and poly(rc) primed for poly(ri), but neither poly(ri) nor poly(rc) primed the cells for the antiviral activity of noncomplementary homopolynucleotides. the priming effect of poly(ri) was significantly reduced if the poly(ri)-primed cells were treated ...19724337160
enzymes specified by dna-containing animal viruses. in: strategy of the viral genome. 19714337203
herpes virus-specified proteins. in: strategy of the viral genome. 19714337207
tissue culture in the laboratory diagnosis of viral infections. 19724337372
effects of pyran copolymer on oncogenic virus infections in immunosuppressed hosts. 19724337673
fluorinated pyrimidines. 41. syntheses of 5-trifluoromethyl-3'-deoxyuridine and 5-fluoro-3'-deoxyuridine. 19724337903
iodine-125-labeled antibody to viral antigens: binding to the surface of virus-infected cells.the specific binding of iodine-125-labeled antibody to viral antigens can be used to detect newly synthesized viral antigens and determine the time of appearance of these antigens on the surface of infected cells. incubation of infected cells with unlabeled antibody to viral antigens specifically blocks the attachment of labeled antibody, and by this inhibition technique the titer of unlabeled antibody to viral antigens can be calculated. the attachment of the labeled antibody to virus-infected ...19724338096
rapid micro-radioimmunoassay for the measurement of antiviral antibody. 19724338438
[effect of sodium salicylate on some viruses]. 19724338512
[studies on the effect of pyrazine derivatives on some dna and rna viruses. i. effect of pyrazine amidrazone and products of its condensation with aldehydes and ketones on adsorption and replication of polio, wee and vaccinia viruses]. 19724338513
action of an alcoholic solution of iodine on the scrapie agent. 19724338603
superinfection of hvj carrier hela cells with ultraviolet-irradiated newcastle disease virus. 19724339055
anti-vaccinia activity of -thiochromanone-1-thiosemicarbazone in vitro and in vivo. 19724339056
[method of infection and pathogenesis of human embryonic virus diseases]. 19724339146
[ineffectiveness of rifomycin in the treatment of vaccinia pneumonia in the mouse]. 19724339206
the mechanism of action of aflatoxin b 1 ; observations on virus-infected cells. 19724339403
[isoprinosine: evaluation of its virus inhibiting action in vivo and in vitro]. 19724339680
[experimental study of the antiviral activity of distamycin a. (preliminary note)]. 19724339706
microelectrophoresis of enzyme and chemically treated viruses and cores of vaccinia, buffalopox, variola and alastrim. 19724340283
swine interferon. i. induction in porcine cell cultures with viral and synthetic inducers.the production of interferon by porcine kidney (pk(15)) cell culture in response to viral and synthetic inducers was studied. the inducers used included a synthetic double-stranded polyribonucleotide, polyriboinosinic-polyribocytidylic acid (poly i:c), swine influenza virus and three strains of pseudorabies virus. following exposure to these inducers cell culture fluids were examined for interferon by the plaque-reduction method. the poly i:c and the swine influenza virus induced production of i ...19724340345
host-cell reactivation in mammalian cells. ii. survival of herpes simplex virus and vaccinia virus in normal human and xeroderma pigmentosum cells. 19724340741
synthesis of dna from vaccinia messenger rna templates. 19724340793
broad-spectrum antiviral activity of virazole: 1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide.virazole is a synthetic nucleoside active in tissue culture against at least 16 dna and rna viruses. applied topically, it inhibits herpetic keratitis in rabbits and tail lesions induced by herpes, vaccinia, and vesicular stomatitis viruses in mice. injected intraperitoneally into mice, it inhibits splenomegaly and hepatomegaly induced by friend leukemia virus and respiratory infections caused by influenza a(o), a(2), and b viruses and parainfluenza 1 virus. infections is also effective.19724340949
histopathology of tumor regression after intralesional injection of mycobacterium bovis., 2. comparative effects of vaccinia virus, oxazolone, and turpentine. 19724341404
elimination of mycoplasma contaminants from virus stocks by treatment with nonionic detergents.five nonionic detergents (tweens 20, 40, 60, and 80, and triton wr-1339) were tested for their ability to inactivate four mycoplasma species which are common contaminants of animal cell cultures. tween 20 was found to be the most effective, in that a concentration of 2.5 mg/ml completely inactivated cultures of m. hominis, m. hyorhinis, and acholeplasma laidlawii within 1 hr and a culture of m. orale within 3 hr. the other detergents exhibited various degree of activity against the different myc ...19724341521
sensitivity of ribonucleic acid and deoxyribonucleic acid viruses to different species of interferon in cell cultures.although two deoxyribonucleic acid (dna) viruses, pseudorabies (psrv) and vaccinia, are as susceptible as a ribonucleic acid (rna) virus, vesicular stomatitis (vsv), to interferon when tested in chicken or mouse cells, they are refractory to inhibition in interferon-treated primary rabbit kidney cells and in a continuous line (rk-13) of rabbit kidney cells. superinfection with vsv of rk-13 cells first infected with psrv completely blocks the replication of psrv with no effect on vsv yield. when ...19724342236
antiviral properties of 1-allyl and 1-crotyl derivatives of 2-( -hydroxybenzyl) benzimidazole. 19724342512
[elimination of resistance of transformed cells in mixed infection]. 19724342658
[on antiviral antibodies in colostrum and milk. 3]. 19724343288
[virus infected lymphoblasts acting as antigen for the production of heterologous antilymphocyte sera]. 19724343424
interferon-inducing polycarboxylates: mechanism of protection against vaccinia virus infection in mice.the present study was undertaken to examine possible correlations between long-term protection of mice treated with polycarboxylates and infected with vaccinia virus, and the presence of subdetectable amounts of interferon in the tissues, as determined by tissue or organ resistance to replication of viruses. after a single dose of polycarboxylate, splenic resistance to virus replication could be detected. it persisted for 7 to 14 days, but no attempt was made to prove that it was due to subdetec ...19724344092
demonstration of cytotoxic antibodies in rabbits bearing tumors induced by shope fibroma virus.the (51)cr-release test was used to detect cytotoxic antibodies in adult rabbits bearing tumors induced by shope fibroma virus. the following are the recommended experimental conditions: the infection of rk-13 cells with a multiplicity of 1 to 2 infectious units per cell for 48 hr, (51)cr labeling of infected cells during the last 12 hr of incubation, sensitization of suspended labeled infected cells for 1 hr with immune serum, and quantitation of cell damage by the amount of (51)cr released aft ...19724344218
the in vitro antiviral activity of a triazinoindole (sk&f 40491). 19724344266
preparation of a number of 5-butylpyrimidine nucleosides. 19724344370
simplified radioimmunoassay for diagnostic serology.a simplified, indirect radioimmunoassay is described for escherichia coli, vaccinia virus, and herpesvirus. the antigens were affixed to glass cover slips; thus both the primary and secondary reactions take place on the cover slips, and the unbound antiserum is easily separated from the bound antiserum by rinsing. rabbit or human immune sera were reacted with the antigens, and the primary immune complex was quantitated by a secondary reaction with (125)i-indicator globulin (anti-rabbit or anti-h ...19724344958
[hematologic changes and viral infection. i. leukopenia and its physiopathology]. 19724345451
mechanism of interferon action: inhibition of viral messenger ribonucleic acid translation in l-cell extracts.encephalomyocarditis (emc) virus ribonucleic acid (rna) stimulated the incorporation of (14)c-amino acids into polypeptides in cell-free systems using preincubated s10 extracts from l cells. incorporation was linear for over 2 hr. analysis of the tryptic peptides derived from the polypeptide products formed in response to emc rna showed them to be virus specific. the major product, a polypeptide of 140,000 in molecular weight, migrated on sodium dodecyl sulfate-polyacrylamide gels with one of th ...19724345494
cytotoxic effect of viruses on harding-passey melanoma in tissue culture. 19734348043
infection-mediated resistance to cell fusion by inactive sendai virus. 19734348100
sensitivity of human conjunctival tissue cultures to adenovirus 8, herpes simplex and vaccinia viruses. induction of resistance by an interferon inducer. 19734348101
[synthesis of bis-homoanalogues of nucleosides]. 19724348119
polyacrylamide gel electrophoresis of fowlpox and vaccinia virus proteins. 19734348307
[the production of an enhancing factor]. 19724348327
virus antigens on the surface of infected cells: binding and elution of ( 125 i)-labelled antivirus antibody. 19734348852
comparison of direct and indirect solid-phase microradioimmunoassays for the detection of viral antigens and antiviral antibody.viral antigens were fixed to the surface of microtiter wells, and serial dilutions of antiviral antibody were added. the amount of antiviral antibody bound to viral antigens was determined by measuring the extent to which the antiviral antibody either inhibited the specific binding of (125)i-labeled antiviral immunoglobulin g (igg) (direct technique) or enhanced the specific binding of (125)i-labeled anti-igg (indirect technique). immune complexes composed of viral antigens and antiviral antibod ...19734349247
experience with an image-analyzing computer in virus plaque measurements.due to the extremely fast and reliable plaque-number determinations, the image-analyzing computer is most useful for large screening programs involving plaque-reduction tests.19734349251
cell surface antigen on quail cells infected with herpesvirus of turkey or marek's disease virus. 19724349460
a bacterial protein inducing antiviral resistance and high titers of interferon. 19724349829
antiviral properties of five strains of corynebacterium. 19724349830
dna virus inhibitory activity of 1- -d-arabinofuranosylcytosine-3',5'-cyclic phosphate. 19734349901
further studies with precipitation in gel test in diagnosis of smallpox. i. studies on detection of antibodies in sera by pig test. 19724350577
antiviral activity of isoprinosine in vitro and in vivo. 19734350802
[synthesis and antiviral effects of adamantan derivatives]. 19734351043
isolation and identification of trachoma and inclusion conjunctivitis agents in melbourne, 1966 to 1972. 19734351871
further studies of viral antibodies in the cerebrospinal fluid of patients with multiple sclerosis: vaccinia and parainfluenza type 1. 19734352535
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