Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| genetic characterisation of african swine fever viruses from recent and historical outbreaks in sardinia (1978-2009). | three discrete regions of the african swine fever virus (asfv) were analysed in the genomes of a wide range of isolates collected from wild and domestic pigs in sardinia, over a 31-year period (1978-2009). the analysis was conducted by genotyping based on sequence data from three single copy asf genes. the e183l gene encoding the structural protein p54 and part of the gene encoding the p72 protein were used to delineate genotypes, before intra-genotypic resolution of viral relationships by analy ... | 2011 | 21373994 |
| plasma and tissue levels of neuropeptide y in experimental septic shock: relation to hemodynamics, inflammation, oxidative stress, and hemofiltration. | neuropeptide y (npy), a potent vasoconstrictor released from the sympathetic nerves, has been suggested to counterbalance sepsis-induced vasodilation. thus, the changes in plasma and tissue npy concentrations in relation to hemodynamic variables and inflammatory markers in a porcine model of moderate septic shock were investigated. susceptibility of npy to be removed by continuous hemofiltration in two settings has been also studied. thirty-four domestic pigs were divided into five groups: (i) c ... | 2011 | 21375544 |
| developmental changes affecting lectin binding in the vomeronasal organ of domestic pigs, sus scrofa. | this study investigated the developmental changes of glycoconjugate patterns in the porcine vomeronasal organs (vnos) and associated glands (jacobson's glands) from prenatal (9 weeks of gestation) and postnatal (2 days after birth) to the sexually mature stage (6 months old). the vno of pigs (sus scrofa) was examined using the following: dolichos biflorus agglutinin (dba), bandeiraea simplicifolia agglutinin isolectin b4 (bsi-b4), triticum vulgaris agglutinin (wga), ulex europaeus agglutinin i ( ... | 2011 | 21376374 |
| mycobacterium caprae infection in livestock and wildlife, spain. | mycobacterium caprae is a pathogen that can infect animals and humans. to better understand the epidemiology of m. caprae, we spoligotyped 791 animal isolates. results suggest infection is widespread in spain, affecting 6 domestic and wild animal species. the epidemiology is driven by infections in caprids, although the organism has emerged in cattle. | 2011 | 21392452 |
| elevated japanese encephalitis virus activity monitored by domestic sentinel piglets in thailand. | twenty-nine domestic piglets from pig farms located in three provinces of thailand between 2003 and 2004 were used as sentinel animals for japanese encephalitis virus (jev) circulation. piglets were used as sentinel to underline, on one hand, the role of domestic pigs as jev amplifying host and, on another hand, to point out the interest of using sentinel animals for japanese encephalitis surveillance. jev activity was demonstrated through i/ antibody detection using a specific elisa test for th ... | 2011 | 21395418 |
| two cases of reciprocal translocations in domestic pigs producing small litters. | summary: two boars of finnish yorkshire breed were selected for chromosomal analysis because of their small litters. one had a complex three breakpoint reciprocal translocation where the small distal chromosome segments were fused in new combinations between autosomes 2,9 and 14. this boar with a 2n = 38,xy,t(2;9;14)(q23;q22;q25) karyotype had produced approximately 3.3 piglets per litter and its fertility was reduced by 70% compared to average of litter size in finnish yorkshire breed pigs. in ... | 1997 | 21395832 |
| microdialysis assessment of percutaneous penetration of ketoprofen after transdermal administration to hairless rats and domestic pigs. | the study was performed to evaluate the percutaneous penetration of ketoprofen after transdermal administration using a microdialysis technique in pigs, in comparison with rats. ketoprofen release from patches was determined by analysis of the remaining drug content after application to hairless rats and pigs. skin and knee joint penetration of ketoprofen was tested by microdialysis, and recovery was determined by retrodialysis. residual rates in hairless rats and pigs were 68.1 -¦ 1.6% and 81.7 ... | 2011 | 21397690 |
| validation of an automated method for salivary alpha-amylase measurements in pigs (sus scrofa domesticus) and its application as a stress biomarker. | the aim of the current study was to validate an automated spectrophotometric method for salivary alpha-amylase measurement in pigs and evaluate its possible application as a noninvasive stress biomarker. the analytical validation included intra- and interassay precision, linearity under dilution, and limit of detection. in addition, to study the possible use of salivary alpha-amylase as a possible stress marker, 12 crossbred growing pigs of 3-4 months of age were subjected to restraint stress by ... | 2011 | 21398448 |
| intracoronary adiponectin at reperfusion reduces infarct size in a porcine myocardial infarction model. | reperfusion injury (ri) remains an important limitation of myocardial revascularization. the aim of the present study was to evaluate the influence of the intracoronary injection of adiponectin on ri and cardiomyocyte death in a porcine myocardial infarction model. acute infarction in 14 polish domestic pigs was induced by inflation of an over the wire balloon (otw) catheter in the medial left anterior descending artery for 60-ámin. the study group consisted of 7 pigs in which intracoronary adip ... | 2011 | 21399860 |
| second prize: in-vivo physiological impact of alpha blockade on the porcine ureter with distal ureteral obstruction. | alpha blockade has been well described clinically for expulsion of distal ureteral stone. however, the in-vivo effects of a-blockade on ureteral dynamics during stone passage are not clear. we studied the effects of oral alfuzosin on ureteral pressure and peristalsis in a distally obstructed porcine ureter. | 2011 | 21401393 |
| vardenafil effect on ureteric smooth muscle: in vitro study in porcine model. | phosphodiesrase type 5 inhibitors have been recently reported to induce a relaxing effect on ureteral smooth muscle. we conducted an in vitro study to elucidate the relaxing effect of various doses of vardenafil on the porcine ureter. moreover, we propose a porcine ureter model for the evaluation of the effect of different substances on the ureter. | 2011 | 21401398 |
| age-related changes in corticosteroid receptor expression and monoamine neurotransmitter concentrations in various brain regions of postnatal pigs. | negative early life experience may be associated with altered functioning of stress-related systems and may increase vulnerability to diseases later in life. corticosteroids are important mediators of homeostasis and stress and exert their effects via two receptors, the mineralocorticoid receptor (mr) and the glucocorticoid receptor (gr), and through the glucocorticoid-metabolizing enzymes 11ß-hydroxysteroid dehydrogenase (11ß-hsd) types 1 and 2 in a brain-region-specific manner. however, relati ... | 2011 | 21416484 |
| the effect of combined delivery of recombinant human bone morphogenetic protein-2 and recombinant human vascular endothelial growth factor 165 from biomimetic calcium-phosphate-coated implants on osseointegration. | objectives: the delivery of growth factors for enhanced osseointegration depends on the effectiveness of the carrier systems at the bone-implant interface. this study evaluated the effect of solo and dual delivery of recombinant human bone morphogenetic protein-2 (rhbmp-2) and recombinant human vascular endothelial growth factor (rhvegf(165) ) from biomimetically octacalcium phosphate-coated implants on osseointegration. materials and methods: biomimetic implants, bearing either a single growth ... | 2011 | 21418332 |
| foot-and-mouth disease in feral swine: susceptibility and transmission. | experimental studies of foot-and-mouth disease (fmd) in feral swine are limited, and data for clinical manifestations and disease transmissibility are lacking. in this report, feral and domestic swine were experimentally infected with fmdv (a24-cruzeiro), and susceptibility and virus transmission were studied. feral swine were proved to be highly susceptible to a-24 cruzeiro fmd virus by intradermal inoculation and by contact with infected domestic and feral swine. typical clinical signs in fera ... | 2011 | 21418546 |
| welfare assessment in porcine biomedical research - suggestion for an operational tool. | in recent years, increasing interest in using the pig (sus scrofa) for biomedical research has become evident. today, the pig is considered an advantageous alternative animal model for various human diseases and conditions. however, even though a considerable amount of biomedical research has been done on pigs, hardly any studies include systematic welfare assessment. still, it is essential to assess welfare of laboratory pigs, both domestic pig breeds and smaller purpose-bred breeds, as (1) sci ... | 2011 | 21420697 |
| effects of local intracoronary paclitaxel delivery using the remedy transport catheter on neointimal hyperplasia after stent implantation in a porcine model. | to assess the effects of local paclitaxel delivery using the remedy catheter on neointimal hyperplasia in a porcine model and compare these results to commercially available bms and biodegradable polymer-coated paclitaxel-eluting stents (bp-pes). | 2011 | 21421185 |
| prevalence of classical swine fever virus in india: a 6-year study (2004-2010). | a study was undertaken regarding the prevalence of classical swine fever virus (csfv) antibodies and antigens in sera and suspected tissue samples of domestic pigs. the samples were received between january 2004 and september 2010. a total of 594 serum samples from 12 states and 287 tissue samples from 13 states of india were tested using commercial enzyme-linked immunosorbent assay (elisa) kits. the mean prevalence of csfv antibodies in suspected sera was 63.3% (376/594), whereas 76.7% (220/287 ... | 2011 | 21429182 |
| behavioural and cardiac responses towards conspecific distress calls in domestic pigs (sus scrofa). | in domestic pigs, vocalisation can be an indicator of distress and negative emotional states. it might play a role in the transfer of emotion between individuals ('emotional contagion' or 'empathy'), which could result in impaired animal welfare on a group level based on the distress in an individual member of the group. the aim of this study was to characterise the responses of pigs to conspecific distress calls. we performed a playback experiment in an open arena with 24 juvenile german landra ... | 2011 | 21439307 |
| comparative analysis of osseointegration of titanium implants with acid-etched surfaces and different biomolecular coatings. | objectives: an increasing trend toward implantation in complex cases, as well as early loading, is beginning to emerge in dental implantology. long-term stability of the inserted implants greatly depends on the osseointegration process. although there are numerous current research efforts aimed at functionalizing implant surfaces, no single factor has proved to be beneficial for osseointegration. the aim of the present study was to investigate whether a combination coating of collagen i and diff ... | 2011 | 21441047 |
| prevalence of antibody to toxoplasma gondii and trichinella spp. in feral pigs (sus scrofa) of eastern north carolina. | feral pigs (sus scrofa) survive in many climates, reproduce year-round, and are dietary generalists. in the united states, the size and range of the feral pig population has expanded, resulting in greater interaction with humans and domestic swine and increased potential for disease transmission. we conducted a serosurvey in feral pigs from eastern north carolina to determine exposure to the zoonotic parasites, toxoplasma gondii and trichinella spp. between september 2007 and march 2009, blood s ... | 2011 | 21441186 |
| semi-preparative isolation and purification of three tauro-conjugated cholic acids from pulvis fellis suis by hsccc coupled with elsd detection. | coupled with evaporative light scattering detection, a high-speed counter-current chromatography (hsccc) method was applied to the separation and purification of three tauro-conjugated cholic acids of taurochenodeoxycholic acid (tcdca), taurohyodeoxycholic acid (thdca) and taurohyocholic acid (thca) from pulvis fellis suis (pig gallbladder bile) for the first time. the two-phase solvent system composed of chloroform-methanol-water-acetic acid (4:4:2:0.3, v/v/v/v) was selected for the one-step se ... | 2011 | 21442029 |
| the diameter of anodic tio(2) nanotubes affects bone formation and correlates with the bone morphogenetic protein-2 expression in vivo. | introduction: recently, it has been demonstrated that the nanoscale environment is a critical factor for cellular behaviour. it has been shown that the diameter of tio(2) nanotube layers controls the cellular behaviour of cells involved in the bone-forming process in vitro. therefore, the aim of the present study was to investigate the effects of the diameter of tio(2) nanotubes on peri-implant bone formation and the expression of bone matrix proteins in vivo. materials and methods: ninety exper ... | 2011 | 21443609 |
| inside out: modern imaging techniques to reveal animal anatomy. | animal anatomy has traditionally relied on detailed dissections to produce anatomical illustrations, but modern imaging modalities, such as mri and ct, now represent an enormous resource that allows for fast non-invasive visualizations of animal anatomy in living animals. these modalities also allow for creation of three-dimensional representations that can be of considerable value in the dissemination of anatomical studies. in this methodological review, we present our experiences using mri, ct ... | 2011 | 21445356 |
| [standardized selection and its consequences for genetic population structure (examplified by sus scrofa l.)]. | type of selection for total fitness, specific for domestic animals and termed by us standardizing selection, is discussed. consequences of such selection for the population structure genetic are considered taking a population of domestic pigs as an example. examples of effective and ineffective standardizing selection are presented. specific features of genetic determination often quantitative traits detected in analysis of standardizing selection are discussed. | 2011 | 21446188 |
| combined chemical and optical methods for monitoring the early decay stages of surrogate human models. | as the body decays shortly after death, a variety of gases and volatile organic compounds (vocs) constantly emanate. ethical and practical reasons limit the use of human corpses in controlled, time-dependent, intervening experiments for monitoring the chemistry of body decay. therefore the utilization of pig carcasses serves as a potential surrogate to human models. the aim of this work was to study buried body decay in conditions of entrapment in collapsed buildings. six domestic pigs were used ... | 2011 | 21450424 |
| species-specific variation in rela underlies differences in nf-?b activity: a potential role in african swine fever pathogenesis. | african swine fever virus (asfv) is a highly infectious disease of domestic pigs, with virulent isolates causing a rapidly fatal hemorrhagic fever. in contrast, the porcine species endogenous to africa tolerate infection. the ability of the virus to persist in one host while killing another genetically related host implies that disease severity may be, in part, modulated by host genetic variation. to complement transcription profiling approaches to identify the underlying genetic variation in th ... | 2011 | 21450812 |
| quantitative computed tomography in porcine lung injury with variable versus conventional ventilation: recruitment and surfactant replacement. | biologically variable ventilation improves lung function in acute respiratory distress models. if enhanced recruitment is responsible for these results, then biologically variable ventilation might promote distribution of exogenous surfactant to nonaerated areas. our objectives were to confirm model predictions of enhanced recruitment with biologically variable ventilation using computed tomography and to determine whether surfactant replacement with biologically variable ventilation provides ad ... | 2011 | 21460711 |
| vaccination with viral protein-mimicking peptides postpones mortality in domestic pigs infected by african swine fever virus. | periodic outbreaks of african swine fever virus (asfv) infection around the world threaten local populations of domestic pigs with lethal disease and provide grounds for pandemic spread. effective vaccination may bring this threat under control. we investigated the effectiveness of select peptides mimicking viral proteins in establishing a protective immune response. forty-six synthetic peptides based on the analysis of the complete nucleotide sequence of asfv were tested for immunogenicity in m ... | 2011 | 21468582 |
| orthodontic tooth movement into jaw regions treated with synthetic bone substitute. | orthodontic tooth movement is fraught with risks and complications. root resorption is the most frequent and important outcome which may arise due to inappropriate force magnitude or tooth movement into dense or altered bone. this study was aimed to demonstrate histologic changes in tooth roots following movement into a jaw region treated with synthetic bone substitute. another objective was to evaluate the method of experimental tooth movement using an animal model. | 2010 | 21469267 |
| a novel isolation method of brucella species and molecular tracking of brucella suis biovar 2 in domestic and wild animals. | brucella suis biovar 2 is the most common aetiological agent of porcine brucellosis in europe. b. suis biovar 2 is considered to have low zoonotic potential, but is a causative agent of reproductive losses in pigs, and it is thus economically important. the multilocus variable-number of tandem repeats genotyping analysis of 16 loci (mlva-16) has proven to be highly discriminatory and is the most suitable assay for simultaneously identifying b. suis and tracking infections. the aim of this study ... | 2011 | 21474256 |
| xenobiotic metabolizing cytochrome p450 in pig, a promising animal model. | the pig has been used as an important animal model for human studies because of its similarity in size, physiology and disease development. however, in contrast to the extensive data available on the cytochrome p450 (cyp) system for humans and rodents, the data related to pig are limited because of, among others, the presence of intra-species differences (domestic pigs and minipigs). the knowledge of the cyp superfamily in a given experimental animal is crucial for pharmacological and toxicologi ... | 2011 | 21476973 |
| voiding prior to parachuting. | multiple incidents of isolated bladder ruptures have occurred in the military parachuting community after jumps. the aim of this article is to demonstrate the amount of energy it takes to rupture a distended bladder and encourage prejump voiding. | 2011 | 21481808 |
| variable effects of high-dose adrenaline relative to standard-dose adrenaline on resuscitation outcomes according to cardiac arrest duration. | adjustment of adrenaline (epinephrine) dosage according to cardiac arrest (ca) duration, rather than administering the same dose, may theoretically improve resuscitation outcomes. we evaluated variable effects of high-dose adrenaline (hda) relative to standard-dose adrenaline (sda) on resuscitation outcomes according to ca duration. | 2011 | 21482013 |
| genome-wide footprints of pig domestication and selection revealed through massive parallel sequencing of pooled dna. | background: artificial selection has caused rapid evolution in domesticated species. the identification of selection footprints across domesticated genomes can contribute to uncover the genetic basis of phenotypic diversity. methodology/main findings: genome wide footprints of pig domestication and selection were identified using massive parallel sequencing of pooled reduced representation libraries (rrl) representing ∼2% of the genome from wild boar and four domestic pig breeds (large white, la ... | 2011 | 21483733 |
| ileorectal bypass performed entirely through a transanal route in a porcine model. | background: natural orifice transluminal endoscopic surgery (notes), a new frontier of minimally invasive surgery, uses the body's natural orifices to create an access for surgical procedures. this study aimed to verify the technical feasibility of ileorectal bypass performed entirely through a transanal access. methods: the procedure was performed on 10 domestic pigs, after which they were killed. a transanal endoscopic microsurgery (tem) device and endoscopic and laparoscopic instruments were ... | 2011 | 21484531 |
| partial protection against classical swine fever virus elicited by dendrimeric vaccine-candidate peptides in domestic pigs. | we report the immunogenicity of three dendrimeric peptide vaccine candidates for classical swine fever virus (csfv). each dendrimeric construct contained four copies of a b-cell epitope from the e2 glycoprotein of csfv [construct 1: e2 (694-712); 2: e2 (712-727); 3: e2 (829-842)] joined to a t-cell epitope from the ns3 protein (residues 1446-1460). intramuscular immunization of domestic pigs with the different constructs significantly reduced the clinical score after lethal challenge with csfv. ... | 2011 | 21496472 |
| experimental pig model of old myocardial infarction with long survival leading to chronic left ventricular dysfunction and remodeling as evaluated by pet. | a pig model of reduced left ventricular (lv) function and remodeling or chronic heart failure with long survival after myocardial infarction (mi) has not been established. the aim of this study was to evaluate the pathophysiologic status of a pig model of old mi using a series of pet studies. | 2011 | 21498524 |
| [extracorporeal cardiac shock wave therapy improved myocardial micro-vascular circulation after acute myocardial infarction at early stage in pigs]. | to explore the effect of low-energy extracorporeal shock wave therapy to improve myocardial micro-vascular circulation after acute myocardial infarction at the early stage in pig model. | 2011 | 21500558 |
| characterization of a novel porcine enterovirus in domestic pig in hungary. | porcine enteroviruses (pevs) of genus enterovirus are small, non-enveloped viruses with single-stranded, positive sense genomic rna, belonging to the family picornaviridae. the discovery of two distinct serotypes (pev9 and 10) was first reported in 1979. despite the sporadic detection and partial genome sequences of these viruses our knowledge about the prevalence and molecular epidemiology of pev types in domestic pigs is very deficient. in this study, we identified a novel pev from fecal sampl ... | 2011 | 21504800 |
| seroprevalence of toxoplasma gondii infection in domestic pigs in durango state, mexico. | abstract little is known concerning the prevalence of toxoplasma gondii infection in pigs in mexico. antibodies to t. gondii were determined in 1,077 domestic pigs in durango, mexico using the modified agglutination test (mat). two groups (a, b) of pigs were sampled: group a pigs (n=555) were raised in 3 geographical regions in durango state and group b pigs (n=522) were from sonora state but slaughtered in durango city. overall, antibodies to t. gondii were found in 137 (12.7%) of 1,077 pigs, w ... | 2011 | 21506843 |
| hypothesis on the dual origin of the mammalian subplate. | the development of the mammalian neocortex relies heavily on subplate. the proportion of this cell population varies considerably in different mammalian species. subplate is almost undetectable in marsupials, forms a thin, but distinct layer in mouse and rat, a larger layer in carnivores and big-brained mammals as pig, and a highly developed embryonic structure in human and non-human primates. the evolutionary origin of subplate neurons is the subject of current debate. some hypothesize that sub ... | 2011 | 21519390 |
| detection and phylogenetic characterization of human hepatitis e virus strains, czech republic. | to determine the origin of hepatitis e virus in the czech republic, we analyzed patient clinical samples. five isolates of genotypes 3e, 3f, and 3g were obtained. their genetic relatedness with czech strains from domestic pigs and wild boars and patient recollections suggest an autochthonous source likely linked to consumption of contaminated pork. | 2011 | 21529412 |
| successful transfection of genes using aav-2/9 vector in swine coronary and peripheral arteries. | background: gene therapy has attracted attention for its potential to treat several cardiovascular diseases. the use of adeno-associated viral (aav) vectors to facilitate therapeutic gene transfer to suppress intimal hyperplasia is a promising concept. the objective of this study was to analyze the in vivo transduction of a novel recombinant aav-2/9 vector with sm22α promoter, containing β-galactosidase gene (lacz) or green fluorescent protein (gfp) as reporter genes, to the medial layer smooth ... | 2011 | 21529824 |
| long-term evaluation of a selective retrograde coronary venous perfusion model in pigs (sus scrofa domestica). | the lack of suitable target vessels remains a challenge for aortocoronary bypass grafting in end-stage coronary heart disease. this study aimed to investigate the arterialization of cardiac veins as an alternative myocardial revascularization strategy in an experimental long-term model in pigs. selective retrograde perfusion of a coronary vein (aorta to coronary vein bypass, retrobypass) before ligation of the ramus interventricularis paraconalis (equivalent to the left anterior descending arter ... | 2011 | 21535926 |
| pcr-based molecular characterization and insilico analysis of food-borne trematode parasites paragonimus westermani, fasciolopsis buski and fasciola gigantica from northeast india using its2 rdna. | food-borne fluke infections/trematodiases are emerging as a major public health problem worldwide with over 40 million people affected and over 10% of world population at risk of infection. the major concentration of these infections is in southeast asian and western pacific regions, where the epidemiological factors (including the prevalent socio-cultural food habits) are conducive for transmission of these infections. the preponderance of these infections is usually in food deficit poor commun ... | 2011 | 21544167 |
| evaluation of post-farm-gate passive surveillance in swine for the detection of foot and mouth disease in australia. | pigs are considered high risk for the introduction and spread of foot and mouth disease (fmd) in australia. one of the most likely pathways of introduction of fmd into australia would be through the illegal importation of fmd-contaminated meat, which is then fed to feral or domestic pigs. locations where animals from different origins are commingled, such as livestock markets and abattoirs, pose a risk for disease spread. early detection of exotic diseases at these locations is crucial in limiti ... | 2011 | 21546105 |
| protection of european domestic pigs from virulent african isolates of african swine fever virus by experimental immunisation. | african swine fever (asf) is an acute haemorrhagic disease of domestic pigs for which there is currently no vaccine. we showed that experimental immunisation of pigs with the non-virulent ourt88/3 genotype i isolate from portugal followed by the closely related virulent ourt88/1 genotype i isolate could confer protection against challenge with virulent isolates from africa including the genotype i benin 97/1 isolate and genotype x uganda 1965 isolate. this immunisation strategy protected most pi ... | 2011 | 21549789 |
| effects of sustained abdominal aorta compression on coronary perfusion pressures and restoration of spontaneous circulation during cardiopulmonary resuscitation in swine. | objectives: the present study was undertaken to explore whether sustained abdominal aorta compression-cardiopulmonary resuscitation (saac-cpr), as a means, can raise coronary perfusion pressure (cpp) as well as restoration of spontaneous circulation (rosc) during cpr. in the present study, we hypothesised that saac-cpr elevates cpp during cpr and improves rosc, without causing liver laceration. methods: animals were randomised into one of two groups (standard cpr and saac-cpr). ten domestic swin ... | 2011 | 21550162 |
| integration between a percutaneous implant and the porcine small bowel. | inflammatory bowel diseases, cancer or trauma may require removal of all or part of the intestines, leaving the patient with a need to wear external stoma appliances for collection of bowel contents. by connecting the small bowel to a percutaneous port, equipped with a sealing lid, a fully continent and leak proof stoma can be created without a need for permanently wearing stoma appliance. the prerequisites for a connection between a permanent, transabdominal implant and a visceral organ are lar ... | 2011 | 21563306 |
| genotyping of mycoplasma hyopneumoniae in wild boar lung samples. | mycoplasma hyopneumoniae is the etiologic agent of enzootic pneumonia (ep), an important cause of disease-associated losses in swine production and a role of wild boar in recurrent infections can be supposed. genotypes of m. hyopneumoniae from wild boar are unknown but could indicate its role as a potential reservoir. therefore, 34 lung samples being pcr-positive for m. hyopneumoniae from wild boar from the geneva region in switzerland were assayed by genotyping using the p146 and multi-locus se ... | 2011 | 21571452 |
| thermodilution-derived indices for assessment of left and right ventricular cardiac function in normal and impaired cardiac function. | objective:: the aim of this study was to assess whether thermodilution-derived parameters of right and left ventricular cardiac function (right ventricular ejection fraction, global ejection fraction, cardiac function index) are able to track changes of cardiac contractile function and whether they are influenced by substantial preload reduction. design:: prospective animal study. setting:: university-affiliated animal research laboratory. subjects:: domestic pigs. interventions:: sixteen domest ... | 2011 | 21572331 |
| emergence of classical swine fever virus in israel in 2009. | classical swine fever (csf) re-emerged in israel in february 2009 after an absence of 62years. the outbreak occurred on a domestic pig farm in northern israel and affected domestic pigs and wild boar. on the basis of phylogenetic analysis of a 190 base pair fragment of the e2 glycoprotein gene, the israeli csf virus strain belonged to genotype 2.1 and was genetically most similar to a chinese csf virus strain. | 2011 | 21592830 |
| laparoscopic fixation of biologic mesh at the hiatus with fibrin or polyethylene glycol sealant in a porcine model. | background: the objective of this study was to determine the acute and chronic fixation strengths achieved by fibrin or polyethylene glycol (peg) sealants to secure biologic mesh at the esophageal hiatus in a porcine model. methods: for this study, 32 female domestic pigs were divided into four groups of 8 each. the four groups respectively received acute fibrin sealant, acute peg sealant, chronic fibrin sealant, and chronic peg sealant. laparoscopically, a 5.5 × 8.5-cm piece of biodesign surgis ... | 2011 | 21594740 |
| quantitative assessment of cardiac output and left ventricular function by noninvasive phase-contrast and cine mri: validation study with invasive pressure-volume loop analysis in a swine model. | purpose: to validate noninvasive cardiac output measurements of phase-contrast magnetic resonance imaging (pc-mri) and cine mri using an invasive pressure-volume (pv) loop technique on a swine model. materials and methods: we compared three methods for evaluating cardiac function at rest and under pharmaceutical low-dose inotropic infusion conditions: 1) phase-contrast mri, 2) cine mri, and 3) pv loop relationship. these measurements were made in 14 domestic pigs under rest conditions. identical ... | 2011 | 21598342 |
| [artyfechinostomum sufratyfex lane, 1915 (trematoda:echinostomatidae), a parasite of mammals in southern vietnam]. | trematoda artyfechinostomumn sufratyfex lane, 1915 was found in different mammal species of southern vietnam. original measurements of this species from domestic pig, black rat, and asian palm civet are given. | 2011 | 21598669 |
| evolution of endogenous retroviruses in the suidae: evidence for different viral subpopulations in african and eurasian host species. | abstract: background: porcine endogenous retroviruses (pervs) represent remnants of an exogenous form that have become integrated in the domestic pig (sus scrofa) genome. although they are usually inactive, the capacity of gamma1 ervs to infect human cells in vitro has raised concerns about xenotransplantation because the viruses could cross the species barrier to humans. here we have analyzed the evolution of gamma1 ervs in ten species of suidae (suids, pigs and hogs) from eurasia and africa us ... | 2011 | 21609472 |
| parenteral aluminum induces liver injury in a newborn piglet model. | parenteral nutrition-associated cholestasis remains a significant problem, especially for the surgical neonate. aluminum is a toxic element known to contaminate parenteral nutrition. we hypothesize that parenterally administered aluminum causes liver injury similar to that seen in parenteral nutrition-associated cholestasis. | 2011 | 21616246 |
| the consumption of glucose during ex vivo lung perfusion correlates with lung edema. | ex vivo lung perfusion (evlp) has been recently proposed to recondition organs before transplantation from donors with marginal or unacceptable features. the aim of our investigation was to explore glucose consumption during evlp. | 2011 | 21620034 |
| long-term treatment with nifedipine suppresses coronary hyperconstricting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo: possible involvement of rho-kinase pathway. | aims accumulating evidence indicates that coronary vasoconstricting responses are enhanced at the edges of coronary segment implanted with a drug-eluting stent (des) compared with a bare-metal stent (bms) in humans. we have recently demonstrated that rho-kinase pathway plays an important role in des-induced coronary hyperconstricting responses associated with inflammatory changes in pigs in vivo. this study examined whether long-term treatment with calcium channel blocker suppresses des-induced ... | 2011 | 21624903 |
| a comparative assessment of zootherapeutic remedies from selected areas in albania, italy, spain and nepal. | zootherapy is the treatment of human ailments with remedies derived from animals and their products. despite its prevalence in traditional medical practices worldwide, research on this phenomenon has often been neglected in comparison to medicinal plant research. interviews regarding zootherapeutic traditions were conducted with informants from albania, italy, nepal and spain. we identified 80 species used in zootherapeutic remedies, representing 4 phyla in the animal kingdom: annelida, arthropo ... | 2010 | 21625340 |
| a prospective randomized comparison of traditional laparoendoscopic single-site surgery with needlescopic-assisted laparoscopic nephrectomy in the porcine model. | abstract background and purpose: laparoendoscopic single-site (less) surgery produces virtually no scar but is technically challenging because of the loss of triangulation. the objective of this study is to compare classic transumbilical less nephrectomy with needlescopic-assisted laparoscopy (nal) surgery. in doing so, we evaluated whether the addition of a single 2-mm subcostal port could restore triangulation while not jeopardizing recovery or cosmetic outcome in the porcine model. materials ... | 2011 | 21631303 |
| treatment of major vein injury with the hemostatic fleece tachosil by interposing a peritoneal patch to avoid vein thrombosis: a feasibility study in pigs. | vein lacerations in awkward locations are difficult to repair and carry high mortality. the hemostatic fleece, tachosil, is effective in preventing intraoperative bleeding in different settings, but has not been recommended for use in large vein injury. tachosil with a peritoneal patch interposed to avoid vein thrombosis has been reported as a method to obtain hemostasis in vein laceration, but further studies of this method are needed. | 2011 | 21633573 |
| [laparoscopic pancreatic resections in experimental setting and clinical practice]. | pancreatic fistula is a major postoperative complication after pancreatic resection. one of the main risk factors of developing the pancreatic fistula after distal pancreatectomy is the method employed for the management of the pancreatic remnant. | 2011 | 21634100 |
| differential resistance of mammalian sperm chromatin to oxidative stress as assessed by a two-tailed comet assay. | protamines of eutherian species are cysteine-rich molecules that become cross-linked by disulfide bonds during epididymal transit, whereas the protamines of most marsupial species lack cysteine residuals. the present study made use of the differences in protamine structure between eutherian and metatherian mammal spermatozoa to examine the comparative resistance of sperm dna to oxidative damage in three eutherian species (mus musculus, homo sapiens, sus domesticus) and three metatherian species ... | 2011 | 21635811 |
| evaluation of genetic variability in the collared peccary pecari tajacu and the white-lipped peccary tayassu pecari by microsatellite markers. | in this study, the microsatellite technique was used to evaluate the genetic variability in populations of collared and white-lipped peccaries kept in captivity. six primers developed for domestic pigs were used and amplified in both species. they revealed the presence of five polymorphic loci and one monomorphic locus. the polymorphic loci included 4 of the 16 alleles in collared peccaries, and 3 of the 10 alleles in the white-lipped peccaries. polymorphic information content (pic) in both spec ... | 2010 | 21637606 |
| genetic diversity and positive selection analysis of classical swine fever virus isolates in south china. | classical swine fever virus (csfv) causes a highly contagious disease that leads to significant economic losses in the pig industry worldwide. however, there is a paucity of knowledge on the accurate genotyping of csfv isolates in south china. this study genotyped the e2 gene of 14 csfv strains isolated during 2008-2010 from domestic pigs in different districts of south china. phylogenetic analyses revealed that all of the 14 csfv isolates were clustered into genetic subgroup 1.1. this contrasts ... | 2011 | 21643769 |
| the first report of mycobacterium celatum isolation from domestic pig (sus scrofa domestica) and roe deer (capreolus capreolus) and an overview of human infections in slovenia. | mycobacterium celatum, a slowly growing potentially pathogenic mycobacterium first described in humans, is regarded as an uncommon cause of human infection, though capable of inducing invasive disease in immunocompromised hosts. according to some reports, a serious disease due to m. celatum may also occur in individuals with no apparent immunodeficiency. in animals, an m. celatum-related disease has been described in three cases only: twice in a domestic ferret (mustela putorius furo) and once i ... | 2011 | 21647336 |
| outbreak of swine erysipelas in a semi-intensive wild boar farm in spain. | swine erysipelas (se) is a disease caused by the bacterium erysipelothrix rhusiopathiae and is one of the best-known and most serious diseases affecting domestic pigs. however, few studies exist concerning the susceptibility of wild boars to this disease and the role of this species as a reservoir. this study investigates and describes an outbreak of se that occurred on a semi-intensive wild boar breeding farm housing 40 boars in extremadura (sw spain) on 11-18 february 2010. seven animals died, ... | 2011 | 21649879 |
| a pig model for the histomorphometric evaluation of hard tissue around dental implants. | abstract this study aimed to evaluate the frontal bone of swiss domestic pigs as an animal model for the histologic-histomorphometric examination of bony tissue around dental implants. sla surface implants 4.1 mm in diameter and 10 mm in length were inserted into the frontal bones of 9 swiss-domestic pigs. histologic and histomorphometric studies were conducted on the undecalcified sections. histological examinations showed that the specimens contain sufficient amount of bone, which provides hom ... | 2011 | 21651415 |
| middle ear of human and pig: a comparison of structures and mechanics. | animal studies are an essential method to evaluate implants for the middle ear prior to clinical studies. new zealand rabbits, guinea pigs and chinchillas are, among other small mammals, well established animal models, but their auditory system is significantly smaller compared to human. hence, the suitability of the domestic pig (sus scrofa domesticus) as a new animal model for research on the middle ear (me), that would match the human in size, was investigated. | 2011 | 21657989 |
| quality traits of wild boar mould-ripened salami manufactured with different selections of meat and fat tissue, and with and without bacterial starter cultures. | quality traits of wild boar mould-ripened salami were assessed in eight batches produced from two different assortments of meat (hind leg vs. shoulder), fat tissue (backfat from domestic pigs vs. fat tissue from wild boar), and with and without addition of a commercial bacterial starter culture. chemical composition of finished products (day 35) were in compliance with national food codex. batches produced with a bacterial starter culture were generally preferred by taste panels, had significant ... | 2011 | 21664055 |
| heart-lung interactions measured by electrical impedance tomography. | : the clinical value of stroke volume variations to assess intravascular fluid status in critically ill patients is well known. electrical impedance tomography is a noninvasive monitoring technology that has been primarily used to assess ventilation. we investigated the potential of electrical impedance tomography to measure left ventricular stroke volume variation as an expression of heart-lung interactions. the objective of this study was thus to determine in a set of different hemodynamic con ... | 2011 | 21666450 |
| transmission of salmonella between swine farms by the housefly (musca domestica). | the domestic pig is an important source of human salmonellosis, and houseflies are potential mechanical vectors of foodborne salmonella pathogens. in 2005, we recovered 144 salmonella isolates from flies and swine stool samples from 11 farms in taoyuan county and hsin chu county (northwestern taiwan). a total of 71.5% of the isolates were resistant to at least three antibiotics. there were a total of 14 serotypes, and 8 of these serotypes were present in both flies and swine stool samples. some ... | 2011 | 21669083 |
| over-the-wire intravascular ultrasound in an animal model of pulmonary hypertension. | intravascular ultrasound (ivus) measures prognostically important pulsatile flow indexes in patients with pulmonary hypertension (ph). ivus catheters traditionally require a guiding catheter for placement which can impact hemodynamics in small infants because the guiding catheter renders the atrioventricular valve incompetent. | 2011 | 21675851 |
| non-contiguous finished genome sequence of bacteroides coprosuis type strain (pc139). | bacteroides coprosuis whitehead et al. 2005 belongs to the genus bacteroides, which is a member of the family bacteroidaceae. members of the genus bacteroides in general are known as beneficial protectors of animal guts against pathogenic microorganisms, and as contributors to the degradation of complex molecules such as polysaccharides. b. coprosuis itself was isolated from a manure storage pit of a swine facility, but has not yet been found in an animal host. the species is of interest solely ... | 2011 | 21677860 |
| Early response of mechanically exposed dental pulps of swine to antibacterial-hemostatic agents or diode laser irradiation. | The purpose of this study was to compare the effectiveness of an antibacterial and hemostatic agent to diode laser irradiation in the healing of mechanically exposed porcine pulps. | 2011 | 21678669 |
| randomized objective comparison of live tissue training versus simulators for emergency procedures. | there is a lack of objective analysis comparing live tissue and simulator training. this article aims to objectively determine the difference in outcomes. twenty-four air force volunteers without prior experience performing emergency procedures were randomly assigned to receive training in tube thoracostomy (chest tube) and cricothyroidotomy training on either a pig model (sus scrofa domestica) or on the traumaman simulator. one week posttraining, students were tested on human cadavers with obje ... | 2011 | 21679588 |
| pluripotent stem cells and reprogrammed cells in farm animals. | pluripotent cells are unique because of their ability to differentiate into the cell lineages forming the entire organism. true pluripotent stem cells with germ line contribution have been reported for mice and rats. human pluripotent cells share numerous features of pluripotentiality, but confirmation of their in vivo capacity for germ line contribution is impossible due to ethical and legal restrictions. progress toward derivation of embryonic stem cells from domestic species has been made, bu ... | 2011 | 21682936 |
| Genetic differentiation of infected from vaccinated animals after implementation of an emergency vaccination strategy against classical swine fever in wild boar. | Oral emergency vaccination against classical swine fever is a powerful tool to control disease outbreaks among European wild boar and thus to safeguard domestic pigs in affected regions. In the past, when virus detection was mainly done using virus isolation in cell culture or antigen enzyme-linked immunosorbent assays, modified live vaccine strains like C-strain "Riems", were barely detectable after oral vaccination campaigns. Nowadays, the use of highly sensitive molecular techniques has given ... | 2011 | 21684092 |
| enhanced delivery of topically-applied formulations following skin pre-treatment with a hand-applied, plastic microneedle array. | the purpose of this work is to characterize microchannels created by polymeric microneedles, applied by hand, and to demonstrate enhanced delivery of topically applied formulations of lidocaine hydrochloride and methylprednisolone sodium succinate (mpss). 3m's microstructured transdermal system (mts) arrays were applied to domestic swine to demonstrate reliability of penetration, depth of penetration and durability of the structures to repeat application and high force. tissue levels of lidocain ... | 2011 | 21696356 |
| effects of field-manure applications on stratified 17+¦-estradiol concentrations. | the occurrence of the manure-borne estrogen, 17+¦-estradiol (e2), was investigated in laboratory and field soils. in the laboratory, e2 was applied to soil to simulate concentrations found in swine (sus scrofa domestica) manure (5000ngl(-1)). the aqueous-extracted e2 dissipated in the soil by 98% within 1h and was not significantly different from background concentrations (18ng l(-1)) for the duration of the experiment (64h). in the field study, soil cores were taken before and several dates aft ... | 2011 | 21696887 |
| sequencing technologies and genome sequencing. | the high-throughput - next generation sequencing (ht-ngs) technologies are currently the hottest topic in the field of human and animals genomics researches, which can produce over 100 times more data compared to the most sophisticated capillary sequencers based on the sanger method. with the ongoing developments of high throughput sequencing machines and advancement of modern bioinformatics tools at unprecedented pace, the target goal of sequencing individual genomes of living organism at a cos ... | 2011 | 21698376 |
| immobilization of russian vx skin depots by localized cooling: implications for decontamination and medical countermeasures. | the chemical weapon nerve agent known as russian vx (vr) is a potent organophosphorus (op) compound that is much less studied than its vx analogue with respect to toxicity, as well as to the effectiveness of several known countermeasures against it. an anaesthetized domestic swine model was utilized to assess several approaches in mitigating its toxicity, including the utility of cooling vr treated skin to increase the therapeutic window for treatment. the 6h ld(50) for vr topically applied on t ... | 2011 | 21704135 |
| gouleako virus isolated from west african mosquitoes constitutes a proposed novel genus in the family bunyaviridae. | the family bunyaviridae is the most diversified family of rna viruses. we describe a novel prototypic bunyavirus, tentatively named goul+®ako virus, isolated from various mosquito species trapped in c+¦te d'ivoire. the s segment comprised 1,087 nucleotides (nt), the m segment 3,188 nt, and the l segment 6,358 nt, constituting the shortest bunyavirus genome known so far. the virus had shorter genome termini than phleboviruses and showed no evidence of encoded nss and nsm proteins. an uncharacteri ... | 2011 | 21715500 |
| sensitivity and ex vivo validation of finite element models of the domestic pig cranium. | a finite element (fe) validation and sensitivity study was undertaken on a modern domestic pig cranium. bone strain data were collected ex vivo from strain gauges, and compared with results from specimen-specific fe models. an isotropic, homogeneous model was created, then input parameters were altered to investigate model sensitivity. heterogeneous, isotropic models investigated the effects of a constant-thickness, stiffer outer layer (representing cortical bone) atop a more compliant interior ... | 2011 | 21718316 |
| expression, immunolocalization and processing of fertilins adam-1 and adam-2 in the boar (sus domesticus) spermatozoa during epididymal maturation. | fertilin alpha (adam-1) and beta (adam-2) are integral membrane proteins of the adam family that form a fertilin complex involved in key steps of the sperm-oocyte membrane interaction. in the present work, we analyzed the presence of adam-1 and adam-2 mrnas, the spermatozoa proteins' processing and their sub-cellular localization in epididymal samples from adult boars. adam-1 and adam-2 mrnas were highly produced in the testis, but also in the vas efferens and the epididymis. on immunoblots of s ... | 2011 | 21718510 |
| seroepidemiologic survey for chlamydia suis in wild boar (sus scrofa) populations in italy. | we used serology to estimate the prevalence of exposure to chlamydiae in italian populations of wild boars (sus scrofa). sera from 173 hunter-killed wild boars harvested during the 2006-2009 hunting seasons in three italian regions were tested for antibodies to chlamydia suis, chlamydophila pecorum, chlamydophila abortus, and chlamydophila psittaci by the microimmunofluorescence test. antibody titers to chlamydiae ôëñ 1:32 were detected in 110 of the 173 samples tested (63.6%). specific reactivi ... | 2011 | 21719838 |
| evaluation of bioequivalency and toxicological effects of three sources of arachidonic acid (ara) in domestic piglets. | arachidonic acid (ara) and docosahexaenoic acid (dha) are routinely added to infant formula to support growth and development. we evaluated the bioequivalence and safety of three ara-rich oils for potential use in infant formula using the neonatal pig model. the primary outcome for bioequivalence was brain accretion of ara and dha. days 3-22 of age, domestic pigs were fed one of three formulas, each containing ara at ôê+0.64% and dha at ôê+0.34% total fatty acids (fa). control diet ara was provi ... | 2011 | 21722692 |
| guided bone regeneration in pig calvarial bone defects using autologous mesenchymal stem/progenitor cells - a comparison of different tissue sources. | due to donor side morbidity and the absence of osteogenic properties in bone substitutes, there is a growing need for an alternative to traditional bone grafting within the scope of tissue engineering. this animal study was conducted to compare the in-ávivo osteogenic potential of adipose-derived (ad), periosteum-derived (pd) and bone marrow-derived (bm) mesenchymal stem/progenitor cells (msc). autologous mesenchymal stem/progenitor cells of named tissue origin were induced into osteogenic diffe ... | 2011 | 21723141 |
| seroprevalence of taenia solium infections in croatian patients presenting with epilepsy. | epilepsy is one of the most common neurological disorders, while neurocysticercosis caused by taenia solium infection of the central nervous system currently represents the leading cause of secondary epilepsy in central and south america, east and south asia, and sub-saharan africa. as a result of increased migration from these endemic regions, neurocysticercosis and subsequent epilepsy are becoming a growing public health problem in developed countries as well. in order to determine the prevale ... | 2011 | 21729385 |
| epidemiological and clinical aspects of human brucella suis infection in polynesia. | summaryhigh brucellosis seroprevalence rates in domestic swine herds have been reported in wallis and futuna islands and are associated with a significant burden of human infection by brucella suis, a species that is rarely incriminated in human disease. between 2003 and 2010, seven patients had a positive blood culture for b. suis biovar 1, 11 symptomatic patients had a positive rose bengal test (rbt) and a positive serum agglutination test (sat) and three asymptomatic cases were found to be po ... | 2011 | 21733252 |
| genetic characterization and phylogeography of the wild boar sus scrofa introduced into uruguay. | the european wild boar sus scrofa was first introduced into uruguay, in southern south america during the early decades of the last century. subsequently, and starting from founder populations, its range spread throughout the country and into the neighbouring brazilian state rio grande do sul. due to the subsequent negative impact, it was officially declared a national pest. the main aim in the present study was to provide a more comprehensive scenario of wild boar differentiation in uruguay, by ... | 2011 | 21734838 |
| development of lidocaine-coated microneedle product for rapid, safe, and prolonged local analgesic action. | purpose: to demonstrate rapid (~1-ámin) lidocaine delivery using 3m's solid microstructured transdermal system (smts) for prolonged, local analgesic action. methods: polymeric microneedles were fabricated via injection molding and then dip-coated using an aqueous lidocaine formulation. the amount of lidocaine coated onto the microneedles was determined by high performance liquid chromatography (hplc). to assess drug delivery and dermal pharmacokinetics, lidocaine-coated microneedles were inserte ... | 2011 | 21735335 |
| [hepatitis e as zoonosis]. | the hepatitis e virus (hev) the causative agent of hepatitis e, is a non-enveloped rna virus. hev is transmitted through oral consumption of contaminated food and water according to the currently knowledge now be considered as zoonosis. the main reservoir of hev are pigs, boars and deer. for the first time hev was isolated from animals (pigs) in 1997 in the u.s. genetic analysis of strains isolated from pigs showed high similarity to strains hev isolated from humans. this was the first evidence ... | 2011 | 21735829 |
| pathologic evaluation of hemostatic agents in percutaneous nephrolithotomy tracts in a porcine model. | abstract background and purpose: hemostatic agents have been suggested as an adjunct for tubeless percutaneous nephrolithotomy (pcnl). we pathologically evaluated the percutaneous tracts injected with the fibrin sealant (fs) evicel and hemostatic gelatin matrix (hgm) surgiflo at various time intervals to determine their absorption and tract closure rates. we also evaluated whether these agents reduced urine leak rates in a porcine model. materials and methods: percutaneous access was obtained in ... | 2011 | 21740197 |
| current perspectives on the phylogeny of filoviridae. | sporadic fatal outbreaks of disease in humans and non-human primates caused by ebola or marburg viruses have driven research into the characterization of these viruses with the hopes of identifying host tropisms and potential reservoirs. such an understanding of the relatedness of newly discovered filoviruses may help to predict risk factors for outbreaks of hemorrhagic disease in humans and/or non-human primates. recent discoveries such as three distinct genotypes of reston ebolavirus, unexpect ... | 2011 | 21742058 |
| comparison of the compression anastomosis ring (endocar) with a circular stapled anastomosis in a porcine model. | purpose. the aim of this study was to compare characteristics of rectal compression and stapled anastomoses at multiple time points. methods. a total of 50 domestic pigs underwent a rectal anastomosis with a compression device or a circular stapler. they were sacrificed at zero-time, 2 days, 1 week, 1 month, and 3 months. burst and maximal tolerated pressure and sites of failure, internal diameters, and radiographic leak rates were assessed. desmosine (elastin) levels were determined. results. t ... | 2011 | 21742666 |
| diabetes mellitus negatively affects peri-implant bone formation in the diabetic domestic pig. | von wilmowsky c, stockmann p, harsch i, amann k, metzler p, lutz r, moest t, neukam fw, schlegel ka: diabetes mellitus negatively affects peri-implant bone formation in the diabetic domestic pig. j clin periodontol 2011; 38: 771-779. doi: 10.1111/j.1600-051x.2011.01746.x. abstract: aim: diabetes mellitus is classified as a relative contraindication for implant treatment, and higher failure rates have been seen in diabetic patients. the aim of the present study was to investigate the effect of di ... | 2011 | 21752046 |
| mrna expression profiles of p450 3a enzymes in the liver and small intestine of the domestic pig. | the cytochrome p450 (p450) 3a family is considered to be the most important and abundantly expressed p450 subfamily in mammals. the mrna expression levels of four p450 3a enzymes in porcine liver and small intestine were investigated using real-time reverse transcriptase-polymerase chain reaction (rt-pcr). the expression of p450 3a mrnas (p450 3a pool) was higher in the liver than that in the small intestine. in the small intestine, the p450 3a mrnas were gradually decreased from the duodenum to ... | 2011 | 21752411 |
| sildenafil prevents the increase of extravascular lung water and pulmonary hypertension after meconium aspiration in newborn piglets. | 2011 | 21755265 |