Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| Comparative Genomics of Helicobacter pylori and the human-derived Helicobacter bizzozeronii CIII-1 strain reveal the molecular basis of the zoonotic nature of non-pylori gastric Helicobacter infections in humans. | ABSTRACT: | 2011 | 22039924 |
| neonatal fc receptor for igg (fcrn) expressed in the gastric epithelium regulates bacterial infection in mice. | neonatal fc receptors for immunoglobulin (ig)g (fcrn) assume a central role in regulating host igg levels and igg transport across polarized epithelial barriers. we have attempted to elucidate the contribution of fcrn in controlling helicobacter infection in the stomach. c57bl/6j wild-type or fcrn(-/-) mice were infected with helicobacter heilmannii, and gastric lesions, bacterial load and the levels of antigen-specific igg in serum and gastric juice were analyzed. the elevated levels of anti-h. ... | 2012 | 22089027 |
| prevalence of non helicobacter pylori species in patients presenting with dyspepsia. | helicobacter species associated with human infection include helicobacter pylori, helicobacter heilmannii and helicobacter felis among others. in this study we determined the prevalence of h. pylori and non-helicobacter pylori organisms h. felis and h. heilmannii and analyzed the association between coinfection with these organisms and gastric pathology in patients presenting with dyspepsia. biopsy specimens were obtained from patients with dyspepsia on esophagogastroduodenoscopy (egd) for rapid ... | 2012 | 22226326 |
| the clinical aspects of helicobacter heilmannii infection in children with dyspeptic symptoms. | helicobacter heilmannii (h. heilmannii) infection is a relatively rare causative agent of gastroduodenal diseases in children. however, h. heilmannii frequently colonizes gastric mucosa of animals, mainly cats and dogs, from where it can be transmitted to humans. the aim of the study was to evaluate the incidence of h. heilmannii infection in children with dyspeptic symptoms treated in our clinic. a number of 13,124 esophagogastroduodenoscopies in children aged 4 to 18 years were conducted from ... | 2012 | 22653899 |
| helicobacter heilmannii gastritis in a young patient with a pet. | 2012 | 22817795 | |
| overexpression of mir-142-5p and mir-155 in gastric mucosa-associated lymphoid tissue (malt) lymphoma resistant to helicobacter pylori eradication. | micrornas (mirnas) are small non-coding rnas that can function as endogenous silencers of target genes and play critical roles in human malignancies. to investigate the molecular pathogenesis of gastric mucosa-associated lymphoid tissue (malt) lymphoma, the mirna expression profile was analyzed. mirna microarray analysis with tissue specimens from gastric malt lymphomas and surrounding non-tumor mucosae revealed that a hematopoietic-specific mirna mir-142 and an oncogenic mirna mir-155 were over ... | 2012 | 23209550 |
| genome sequence of helicobacter heilmannii sensu stricto asb1 isolated from the gastric mucosa of a kitten with severe gastritis. | here we report the genome sequence of helicobacter heilmannii sensu stricto asb1 isolated from the gastric mucosa of a kitten with severe gastritis. helicobacter heilmannii sensu stricto has also been associated with gastric disease in humans. availability of this genome sequence will contribute to the identification of genes involved in the pathogen's virulence and carcinogenic properties. | 2013 | 23405321 |
| new pharmaceutical treatment of gastric malt lymphoma: anti-angiogenesis treatment using vegf receptor antibodies and celecoxib. | in addition to eradication of helicobacter pylori, chemotherapy with anticancer agents, and radiation therapy, the treatment with molecular target drugs including rituximab, a cd20 antagonist, is one of the promising new regimens. the mucosa-associated lymphoid tissue (malt) lymphoma is histologically characterized by rich distribution of the microvascular network consisting of the immature capillaries, lymphatics and venules, and this microvascular network could be the target of the new pharmac ... | 2014 | 23782142 |
| diversity in bacterium-host interactions within the species helicobacter heilmannii sensu stricto. | helicobacter (h.) heilmannii sensu stricto (s.s.) is a zoonotic bacterium that naturally colonizes the stomach of dogs and cats. in humans, this microorganism has been associated with gastritis, peptic ulcer disease and mucosa associated lymphoid tissue (malt) lymphoma. little information is available about the pathogenesis of h. heilmannii s.s. infections in humans and it is unknown whether differences in virulence exist within this species. therefore, a mongolian gerbil model was used to study ... | 2013 | 23895283 |
| gastric and enterohepatic non-helicobacter pylori helicobacters. | a substantial number of reports published in the last year have contributed to a better understanding of both human and animal infection with non-helicobacter pylori helicobacter species (nhph). gastric infection of humans with helicobacter suis and helicobacter felis as well as unidentified nhph has been described to cause a chronic gastritis and a variety of clinical symptoms, whereas enterohepatic nhph, including helicobacter cinaedi, helicobacter bilis, and helicobacter canis, have been repo ... | 2013 | 24011248 |
| gastric helicobacter spp. infection in captive neotropical brazilian feline. | ten captive neotropical brazilian feline were submitted to gastroscopic examination and samples of gastric mucosa from fundus, corpus and pyloric antrum were evaluated for the presence of helicobacter species. warthin-starry (ws) staining and pcr assay with species-specific primers and enzymatic cleavage were applied for bacterial detection and identification. histological lesions were evaluated by haematoxylin and eosin staining. all animals showed normal gross aspect of gastric mucosa. helicob ... | 2011 | 24031634 |
| determination of the prevalence of helicobacter heilmannii-like organisms type 2 (hhlo-2) infection in humans and dogs using non-invasive genus/species-specific pcr in korea. | helicobacter spp. may have multiple routes of transmission. it is unclear, however, whether the agent is zoonotic and therefore transmitted from an animal reservoir, including dogs. the aim of this population-based study was to assess the relationship between pet ownership or frequent exposure to dogs and helicobacter spp. infection, especially focusing on hhlo-2 (helicobacter heilmannii-like organisms type 2) in saliva and feces samples in korea, using non-invasive genus/species-specific pcr. o ... | 2013 | 24065079 |
| helicobacter heilmannii sensu stricto-related gastric ulcers: a case report. | a spiral bacterium (sh9), morphologically different from helicobacter pylori (h. pylori), was found in a 62-year-old woman's gastric mucosa. gastroscopic examination revealed multiple gastric ulcers near the pyloric ring; mapping gastric biopsy showed mild mononuclear infiltration with large lymphoid follicles in the antrum, without corpus atrophy. urea breath test and h. pylori culture were negative, but giemsa staining of biopsies revealed tightly coiled bacteria that immunostained with anti-h ... | 2014 | 24695914 |
| gastric de novo muc13 expression and spasmolytic polypeptide-expressing metaplasia during helicobacter heilmannii infection. | helicobacter heilmannii is a zoonotic bacterium that has been associated with gastric disease in humans. in this study, the mrna expression of mucins in the stomach of balb/c mice was analyzed at several time points during a 1-year infection with this bacterium, during which gastric disease progressed in severity. markers for acid production by parietal cells and mucous metaplasia were also examined. in the first 9 weeks postinfection, the mrna expression of muc6 was clearly upregulated in both ... | 2014 | 24866791 |
| prevalence of coinfection with gastric non-helicobacter pylori helicobacter (nhph) species in helicobacter pylori-infected patients suffering from gastric disease in beijing, china. | the helicobacter heilmannii sensu lato (h. heilmannii s.l.) group consists of long, spiral-shaped bacteria naturally colonizing the stomach of animals. moreover, bacteria belonging to this group have been observed in 0.2-6% of human gastric biopsy specimens, and associations have been made with the development of chronic gastritis, peptic ulceration, and gastric malt lymphoma in humans. | 2015 | 25510739 |
| alteration of angiogenesis in helicobacter heilmannii-induced mucosa-associated lymphoid tissue lymphoma: interaction with c-met and hepatocyte growth factor. | the hepatocyte growth factor (hgf)/c-met pathway has attracted attention in the formation of malignant tumors, as hgf secreted from the microcirculatory components as well as residing macrophages has been suggested to act on the c-met receptors of cancer cells to decrease apoptosis and increase proliferation, invasion, and metastasis. the present study was undertaken to elucidate the interaction of the gastric, hepatic, and pulmonary mucosa-associated lymphoid tissue (malt) lymphoma induced by h ... | 2014 | 25521737 |
| helicobacter heilmannii sensu lato: an overview of the infection in humans. | helicobacter heilmannii sensu lato (h. heilmannii s.l.) is a group of gastric non-helicobacter pylori helicobacter species that are morphologically indistinguishable from each other. h. heilmannii s.l. infect the stomach of several animals and may have zoonotic potential. although the prevalence of these infections in humans is low, they are associated with gastric pathology, including mucosa-associated lymphoid tissue lymphoma, making them a significant health issue. here, the taxonomy, epidemi ... | 2014 | 25548476 |
| a mixed population of helicobacter pylori, helicobacter bizzozeronii and "helicobacter heilmannii" in the gastric mucosa of a domestic cat. | the presence of helicobacter within the gastric mucosa is responsible for producing pathology in many animal species, including man. since humans have been shown to harbour many of the same bacterial species as domestic carnivores, concern over their zoonotic potential has been growing. helicobacter pylori, a class 1 carcinogen responsible for cases of gastritis and gastric cancer in humans, produces similar pathology in pet carnivores and is considered an example of anthroponosis. the case here ... | 2014 | 25905013 |
| helicobacter suis-infected nodular gastritis and a review of diagnostic sensitivity for helicobacter heilmannii-like organisms. | helicobacter heilmannii-like organisms (hhlos) are associated with mucosa-associated lymphoid tissue lymphoma and peptic ulcer. however, the sensitivity of diagnostic tests for hhlos, such as rapid urease test (rut), urea breath test (ubt) and blood antibody, is not high. tightly coiled spiral microorganisms were found in the gastric mucosal biopsy specimen of a 48-year-old asymptomatic woman. her findings were positive for rut and ubt, but negative for blood antibody and stool antigen against h ... | 2017 | 26120299 |
| comparison of three diagnostic assays for the identification of helicobacter spp. in laboratory dogs. | a number of helicobacter species may confound experimental data because of their association with disease progressing in various kinds of laboratory animals. screening of helicobacter species is particularly desirable, because they are prevalent in commercial and research animal facilities. the aim of the present study was to compare three diagnostic methods [e.g. helicobacter stool antigen kit (hpsa), polymerase chain reaction (pcr) and rapid urease test (rut)] for the identification of helicob ... | 2015 | 26155203 |
| [role of animal gastric helicobacter species in human gastric pathology]. | animal helicobacter species other than helicobacter pylori are also able to cause human gastritis, gastric ulcers, and malt lymphomas. animal helicobacter species are presented with typical spiral fastidious microorganisms colonizing the gastric mucosa of different animals. bacteria initially received their provisional name helicobacter heilmannii, and out of them at least five species colonizing the gastric mucosa of pigs, cats, and dogs were isolated later on. a high proportion of these diseas ... | 2015 | 26155631 |
| a case of helicobacter heilmannii-associated primary gastric mucosa-associated lymphoid tissue lymphoma achieving complete remission after eradication. | a 46-year-old man underwent gastrointestinal endoscopy while visiting the hospital for a general physical check-up. coarse mucosa in the antrum with superficial erosions was found by endoscopic gastrointestinal examination, but no atrophic changes were seen in the corpus. histopathological examination of gastric biopsy specimens revealed mucosa-associated lymphoid tissue (malt) lymphoma. although helicobacter pylori was not detected in our patient, h. heilmannii was identified histologically and ... | 2013 | 26181403 |
| complete remission of gastric plasmacytoma following eradication of "candidatus helicobacter heilmannii". | this is the first case report of gastric plasmacytoma associated with "candidatus helicobacter heilmannii" ('h. heilmannii') infection. the patient was a 40-year-old woman with epigastric discomfort. upper gastrointestinal endoscopy demonstrated a white granular lesion on the wall of the gastric body. histological studies showed numerous eosinophilic globules expanding the lamina propria mucosae. immunohistochemically, the cells with these globules stained positive for cd138, cd79a, immunoglobul ... | 2012 | 26182161 |
| helicobacter heilmannii-like organism in parietal cells: a diagnostic pitfall. | 2016 | 26345479 | |
| anti-treponema antibody also stains helicobacter heilmannii. | 2016 | 26509908 | |
| divergence between the highly virulent zoonotic pathogen helicobacter heilmannii and its closest relative, the low-virulence "helicobacter ailurogastricus" sp. nov. | helicobacter heilmannii naturally colonizes the stomachs of dogs and cats and has been associated with gastric disorders in humans. nine feline helicobacter strains, classified as h. heilmannii based on ureab and 16s rrna gene sequences, were divided into a highly virulent and a low-virulence group. the genomes of these strains were sequenced to investigate their phylogenetic relationships, to define their gene content and diversity, and to determine if the differences in pathogenicity were asso ... | 2015 | 26527212 |
| atrophic gastritis: helicobacter pylori versus duodenogastric reflux. | the objective of this study was to asses the prevalence of atrophic gastritis in children. we also wanted to compare the clinical manifestation, endoscopic appearance and the degree of the gastric atrophy in children and to identify the possible causes which determine gastric atrophy. | 2013 | 26527935 |
| the helicobacter heilmannii hofe and hoff genes are essential for colonization of the gastric mucosa and play a role in il-1β-induced gastric muc13 expression. | helicobacter heilmannii is a zoonotic bacterium associated with gastric disease in humans. we recently showed that h. heilmannii binds to human gastric mucins and epithelial cells and highlighted a potential role for the murine muc13 mucin in gastric helicobacter colonization. the aims of this study were to investigate the role of the h. heilmannii hof gene locus encoding hofh/f/e/g/c/d in adhesion to the gastric mucosa and induction of increased gastric muc13 expression. | 2016 | 26935145 |
| detection of helicobacter spp. in the saliva of dogs with gastritis. | the aim of this study was to identify the species and determine the prevalence of gastric helicobacter in the saliva of dogs with gastritis. the study was carried out on 30 dogs of different breeds, genders and ages, which were diagnosed with gastritis. the nested-pcr method was used to detect helicobacter spp. in saliva. helicobacter bacteria were found in the saliva samples of 23 (76.6%) dogs. helicobacter heilmannii was the most commonly detected species of gastric helicobacter spp. in canine ... | 2016 | 27096797 |
| detection of gastric helicobacter spp. in stool samples of dogs with gastritis. | the aim of this study was to determine the prevalence and identify the species of gastric helicobacter in the stool of dogs with gastritis. the study was carried out on thirty dogs of different breeds, of both genders and of various ages, diagnosed with gastritis. helicobacter spp. was detected in stool samples using the nested-pcr method. helicobacter bacteria were identified in stool samples from seven (23.3%) dogs. helicobacter heilmannii was found to be the most common species of gastric hel ... | 2016 | 27487496 |
| epidemiological study on feline gastric helicobacter spp. in japan. | epidemiological and pathological studies on helicobacter spp. in feline stomachs in japan were conducted using genus- and species-specific (h. felis, h. bizzozeronii, h. heilmannii sensu stricto [s.s.] and h. pylori) polymerase chain reactions (pcrs), ureab gene sequencing and histopathology. pcr results showed that 28 of 56 cats were infected with helicobacter spp., and h. heilmannii s.s. was the most prevalent species by both pcr (28/28) and ureab gene sequencing (26/28). some of the sequences ... | 2017 | 28367842 |
| cloning of helicobacter suis cholesterol α-glucosyltransferase and production of an antibody capable of detecting it in formalin-fixed, paraffin-embedded gastric tissue sections. | helicobacter suis (h. suis), formerly called helicobacter heilmannii type 1 (h. heilmannii), is a gram-negative bacterium of the helicobacter species. this pathogen infects the stomach of humans and animals such as dogs, cats, pigs, and rodents, the latter giving rise to zoonotic infection. here, we generated a h. suis-specific antibody useful for immunohistochemistry with formalin-fixed, paraffin-embedded tissue sections. to do so, we began by cloning the gene encoding h. suis cholesterol α-glu ... | 2017 | 28534071 |
| epidemiological study of gastric helicobacter spp. in dogs with gastrointestinal disease in japan and diversity of helicobacter heilmannii sensu stricto. | epidemiological and pathological studies of helicobacter spp. in canine stomachs in japan were performed to investigate strain specific pathogenicity. gastric biopsies from 144 dogs with gastrointestinal diseases were evaluated for the presence of helicobacter spp. using genus and species specific pcrs for helicobacter felis, helicobacter bizzozeronii, helicobacter heilmannii sensu stricto (s.s.) and helicobacter pylori. pcr indicated that 50/144 (34.7%) dogs were infected with helicobacter spp. ... | 2017 | 28720300 |