Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| treatment outcome for iddm patients in relation to glutamic acid decarboxylase autoantibodies and serum igg to periodontal pathogens. | patients with insulin-dependent diabetes mellitus (iddm) have elevated risk for periodontitis (pd) relative to subjects without diabetes. whether refractory pd in iddm patients is related to autoimmunity as indicated by serum glutamic acid decarboxylase autoantibody gad ab levels or to host bacterial immunity as reflected by serum antibody titers to periodontal pathogens is unknown. | 2001 | 11350522 |
| pcr detection of 5 putative periodontal pathogens in dental plaque samples from children 2 to 12 years of age. | the purpose of this study was to detect the presence of prevotella intermedia, p. nigrescens, bacteroides forsythus, treponema denticola, and campylobacter rectus in plaque samples from 119 children, collected from their toothbrushes using a polymerase chain reaction (pcr). | 2001 | 11350526 |
| bacterial diversity in human subgingival plaque. | the purpose of this study was to determine the bacterial diversity in the human subgingival plaque by using culture-independent molecular methods as part of an ongoing effort to obtain full 16s rrna sequences for all cultivable and not-yet-cultivated species of human oral bacteria. subgingival plaque was analyzed from healthy subjects and subjects with refractory periodontitis, adult periodontitis, human immunodeficiency virus periodontitis, and acute necrotizing ulcerative gingivitis. 16s ribos ... | 2001 | 11371542 |
| [metronidazole in the treatment of refractory periodontitis]. | in this article the clinical and microbiological effects of systemic metronidazole in the treatment of refractory periodontitis in adult patients is discussed. for this study, 27 adult patients with detectable bacteroides forsythus and culture negative for actinobacillus actinomycetemcomitans were selected. after renewed supra- and subgingival debridement, patients were treated with systemic metronidazole (500 mg tid) for 7 days. mean probing pocket depth, probing attachment level and bleeding i ... | 2000 | 11383022 |
| smoking affects the subgingival microflora in periodontitis. | tobacco smoking has been identified as one major risk factor for destructive periodontal disease. scaling and root planing have been shown to be less effective in smokers with periodontitis. the aim of the present study was to compare the subgingival microbial flora of treated and untreated smokers and non-smokers. | 2001 | 11394403 |
| development of a gene inactivation system for bacteroides forsythus: construction and characterization of a bspa mutant. | bacteroides forsythus is a gram-negative anaerobic bacterium associated with periodontitis. the bspa gene encoding a cell surface associated leucine-rich repeat protein (bspa) involved in adhesion to fibronectin and fibrinogen was recently cloned from this bacterium in our laboratory. we now describe the construction of a bspa-defective mutant of b. forsythus. this is the first report describing the generation of a specific gene knockout mutant of b. forsythus, and this procedure should be usefu ... | 2001 | 11402017 |
| change in subgingival microbial profiles in adult periodontitis subjects receiving either systemically-administered amoxicillin or metronidazole. | the current investigation evaluated changes in levels and proportions of 40 bacterial species in subgingival plaque samples during, immediately after and up to 1 year after metronidazole or amoxicillin therapy combined with srp. | 2001 | 11422580 |
| untreated periodontal disease in indonesian adolescents. subgingival microbiota in relation to experienced progression of periodontitis. | in an indonesian population deprived of regular dental care, the experienced progression of disease between baseline (1987) and follow-up (1994) was investigated in relation to the composition of the subgingival microbiota at follow-up. at baseline the age ranged from 15 to 25 years. clinical and microbiological evaluation was completed in 158 of the 167 subjects available at follow-up. | 2001 | 11422582 |
| [bacteriologic investigation of periodontal infections]. | the gingivitis and periodontitis are very common diseases in hungary: more than 80% of the adult population suffers with gingivitis and 15-20% has destructive periodontitis. the composition of peridontopathogenic bacterial flora is totally different from that of the bacterial flora causing dental infections. in periodontal infections dominantly facultative and obligatory anaerobic microorganisms occur (actinobacillus actinomycetemcomitans (a. actinomycetemcomitans), porphyromonas gingivalis (p. ... | 2001 | 11480243 |
| treatment of peri-implantitis by local delivery of tetracycline. clinical, microbiological and radiological results. | the purpose of this study was to investigate the clinical, microbiological and radiological effects of peri-implantitis therapy by local delivery of tetracycline. in 25 partially edentulous patients, 30 implants with radiographic evidence of circumferential bone loss, and peri-implant probing depths > or =5 mm were treated with polymeric tetracycline hcl-containing fibers. clinical and microbial parameters were recorded at baseline, and 1, 3, 6, and 12 months (m) after treatment. standardized ra ... | 2001 | 11488856 |
| clinical and microbiological evaluation of ligature-induced peri-implantitis and periodontitis in dogs. | the purpose of this study was to evaluate the attachment loss around teeth and implants by clinical and microbiological analysis. the mandibular premolars were extracted in 5 mongrel dogs and, 3 months later, two titanium implants were installed on each side of the mandible and, after another 3 months, abutment connection was performed. plaque control in the implants and maxillary premolars was maintained for two weeks prior to the start of the main experiment. on day 0 and 30 days after ligatur ... | 2001 | 11488857 |
| herpes viruses and periodontopathic bacteria in early-onset periodontitis. | this study examined the occurrence of human herpes viruses and suspected periodontopathic bacteria in early-onset periodontitis patients who experienced progressive disease in at least 2 periodontal sites during the maintenance phase of therapy. | 2001 | 11493359 |
| clinical periodontal findings and microflora profiles in children with chronic neutropenia under supervised oral hygiene. | this is the first known case report that used a polymerase chain reaction (pcr)-based method to help identify the oral microflora in patients with chronic neutropenia. in this study, we report clinical periodontal findings and microflora profiles of 2 children, 1 with severe congenital neutropenia (scn, kostmann type) and 1 with cyclic neutropenia (cn). | 2001 | 11495144 |
| humoral immune response in early-onset periodontitis: influence of smoking. | sixty-five patients with generalised early-onset periodontitis (g-eop) (age range 16-42 years, 32 smokers and 33 non-smokers) were assessed for antibody titres and avidity to a panel of five suspected periodontal pathogens (porphyromonas gingivalis, actinobacillus actinomycetemcomitans, prevotella intermedia, treponema denticola and bacteroides forsythus). thirty-four of these patients were untreated (17 smokers and 17 non-smokers), and thirty-one were in the maintenance phase of periodontal the ... | 2001 | 11519695 |
| mixed infection of porphyromonas gingivalis and bacteroides forsythus in a murine abscess model: involvement of gingipains in a synergistic effect. | several microorganisms including porphyromonas gingivalis and bacteroides forsythus have been implicated to be etiologically important agents of periodontal disease. in this study, we determined the ability of combinations of periodontopathogenic microorganisms to cause tissue destruction in a murine abscess model. although all bacterial combinations used in this study produced larger abscesses than did monoinfection of each bacterium, the combination of p. gingivalis and b.forsythus showed a sy ... | 2001 | 11519697 |
| identification of oral spirochetes at the species level and their association with other bacteria in endodontic infections. | recent molecular approaches have revealed that fastidious organisms such as bacteroides forsythus and oral treponemes were frequently found in root canals with apical periodontitis. the purpose of this study was to identify the isolates of oral spirochetes at the species level in endodontic infections and to determine their association with b forsythus and porphyromonas gingivalis. | 2001 | 11552154 |
| the opdb locus encodes the trypsin-like peptidase activity of treponema denticola. | high levels of treponema denticola in subgingival dental plaque are associated with severe periodontal disease. t. denticola, along with porphyromonas gingivalis and bacteroides forsythus, are the only cultivatable oral microorganisms that produce significant amounts of "trypsin-like" peptidase activity. the ability of subgingival plaque to hydrolyze n-alpha-benzoyl-dl-arginine-2-naphthylamide (bana) is associated with high levels of one or more of these organisms. the purpose of this study was ... | 2001 | 11553560 |
| salivary albumin, total protein, iga, igg and igm concentrations and occurrence of some periodontopathogens in hiv-infected patients: a 2-year follow-up study. | hiv infection reduces oral defensive mechanisms and may affect mucosal integrity. differences in salivary protein concentrations and periodontopathogenic bacteria were studied in 56 hiv-infected patients with respect to their disease phase. thirty-three patients were followed up for 2 years. fifty-three healthy subjects of corresponding age and sex were studied as controls. at baseline, salivary albumin, total protein, iga, and igm levels were significantly higher (p<0.05-0.0001) in all phases o ... | 2001 | 11555159 |
| immune response to bacteroides forsythus in a murine model. | a murine skin abscess model was used to study the immune response to an acute infection with bacteroides forsythus. balb/c mice were given subcutaneous injections of either viable or heat-killed b. forsythus, while a third sham-immunized control group received phosphate-buffered saline. weights and lesion sizes were measured. blood was collected from the heart and specific antibodies to b. forsythus measured by an elisa. swabs taken from the lesions and also from pooled blood were cultured anaer ... | 2001 | 11555309 |
| periodontal infections contribute to elevated systemic c-reactive protein level. | periodontitis is a local inflammatory process mediating destruction of periodontal tissues triggered by bacterial insult. however, this disease is also characterized by systemic inflammatory host responses that may contribute, in part, to the recently reported higher risk for cardiovascular disease (cvd) among patients with periodontitis. moderate elevation of c-reactive protein (crp) has been found to be a predictor of increased risk for cvd. elevated crp levels in periodontal patients have bee ... | 2001 | 11577954 |
| periodontal disease as a specific, albeit chronic, infection: diagnosis and treatment. | periodontal disease is perhaps the most common chronic infection in adults. evidence has been accumulating for the past 30 years which indicates that almost all forms of periodontal disease are chronic but specific bacterial infections due to the overgrowth in the dental plaque of a finite number of mostly anaerobic species such as porphyromonas gingivalis, bacteroides forsythus, and treponema denticola. the success of traditional debridement procedures and/or antimicrobial agents in improving p ... | 2001 | 11585783 |
| microbiological evaluation of acute periradicular abscesses by dna-dna hybridization. | the purpose of the present investigation was to examine the microbiota of acute periradicular abscesses of endodontic origin by using a molecular genetic method. | 2001 | 11598583 |
| efficacy of manual and powered toothbrushes (ii). effect on microbiological parameters. | the purpose of the present investigation was to determine the effect of self-performed supragingival plaque removal using either manual (crest complete) or power (braun 3d plaque remover) toothbrushing on supra and subgingival plaque composition. | 2001 | 11686813 |
| absence of a specific subgingival microflora in adults with down's syndrome. | periodontal disease in down's syndrome (ds) is generally characterized by a high degree of bone loss. bone loss of 5 mm or more is observed in 70% of these subjects. among ds subjects, considerable differences in disease progression occur. so far, no studies have been conducted in which specific properties of the subgingival microflora have been related to the condition observed. | 2001 | 11686820 |
| [bacteroides forsythus: sensitivity to antimicrobial agents in samples from patients with periodontitis]. | an in vitro antimicrobial sensitivity test (technique of agar dilution) was carried out for 105 clinical isolates of b. forsythus from patients with periodontitis. metronidazole and amoxicillin were the most efficient drugs and, thus, are indicated for the treatment of periodontal infections in which this microorganism is the most prevalent pathogen. | 2001 | 11708285 |
| association of early onset periodontitis microbiota with aspartate aminotransferase activity in gingival crevicular fluid. | the objective of this study was to determine the relationship between the activity of the enzyme aspartate aminotransferase (ast) in gingival crevicular fluid (gcf) using the colorimetric periogard (ptm) test and the subgingival microflora in early onset periodontitis lesions. | 2001 | 11737506 |
| sulfate-reducing bacteria in relation with other potential periodontal pathogens. | oral sulfate-reducing bacteria are involved in several clinical categories of periodontitis. the aim of this cross-sectional study was to compare the presence of sulfate-reducing bacteria (srb) with other putative pathogens including spirochetes, actinobacillus actinomycetemcomitans, bacteroides forsythus, porphyromonas gingivalis, and treponema denticola in periodontal lesions. | 2001 | 11737513 |
| supragingival and subgingival microbiota of adult patients with down's syndrome. changes after periodontal treatment. | in this longitudinal study, five adult down's syndrome patients with periodontitis were placed on a frequent recall visit schedule (every 6 weeks) after treatment, in order to investigate: 1) the microbiological status, both supragingivally and subgingivally, and the changes that occurred after treatment and 2) the effect of frequent professional supragingival plaque control on the subgingival microbiota and clinical variables in these patients. the clinical variables recorded were probing pocke ... | 2001 | 11737662 |
| bacteroides forsythus prth genotype in periodontitis patients: occurrence and association with periodontal disease. | bacteroides forsythus has been described as a periodontopathogen and its presence in the subgingival plaque can lead to periodontal disease. recently, a cysteine protease designated as prth was isolated and characterized from b. forsythus atcc 43037. the purpose of this study was to determine the prevalence and the association of the prth gene of b. forsythus with periodontal disease. a total of 160 subgingival plaque samples were assayed with the polymerase chain reaction method using oligonucl ... | 2001 | 11762876 |
| one-year compliance and effects of amine and stannous fluoride on some salivary biochemical constituents and oral microbes in institutionalized elderly. | due to old age and poor general health, the institutionalized elderly have often not been used as research subjects for the investigation of oral health protocols. because the number of elderly is increasing, they are an important target group for the development of oral hygiene aids. this trial was designed to investigate whether the institutionalized elderly could successfully use an amine-fluoride- and stannous-fluoride-containing mouthwash and toothpaste during a 12-month period. a dental hy ... | 2001 | 11795450 |
| dialister pneumosintes, a new putative periodontal pathogen. | recent studies have implicated dialister pneumosintes as a candidate periodontal pathogen. this study determined the association of subgingival d. pneumosintes with demographic variables (age and gender) and the presence of subgingival periodontopathic bacteroides forsythus and porphyromonas gingivalis. microbial identification by established pcr techniques was performed in samples from 149 periodontitis patients. subgingival d. pneumosintes occurred with significantly higher prevalence in older ... | 2002 | 11842941 |
| periodontopathic bacterial infection in childhood. | little information is available on periodontopathic bacterial infection in childhood. we assessed the prevalence by age of 10 putative periodontopathic microorganisms in periodontally healthy children using a polymerase chain reaction (pcr) assay. | 2002 | 11846195 |
| periodontal pathogen detection in gingiva/tooth and tongue flora samples from 18- to 48-month-old children and periodontal status of their mothers. | few studies have detected periodontal pathogens in young children, and when detected the prevalence has been relatively low. in this epidemiological study, we determined the prevalence of periodontal pathogen colonization in young children and examined the relationship between periodontitis in mothers and detection of periodontal pathogens in their children aged 18-48 months. children were selected and enrolled randomly into the study; tongue and gingival/tooth plaque samples were harvested and ... | 2002 | 11860557 |
| dependence of bacterial protein adhesins on toll-like receptors for proinflammatory cytokine induction. | toll-like receptors (tlrs) are important signal transducers that mediate inflammatory reactions induced by microbes through pattern recognition of virulence molecules such as lipopolysaccharide (lps) and lipoproteins. we investigated whether proinflammatory cytokine responses induced by certain bacterial protein adhesins may also depend on tlrs. in differentiated thp-1 mononuclear cells stimulated by lps-free recombinant fimbrillin (rfima) from porphyromonas gingivalis, cytokine release was abro ... | 2002 | 11874886 |
| association of bacteroides forsythus and a novel bacteroides phylotype with periodontitis. | chronic periodontitis is a common infectious disease in the adult population. the etiology is clearly bacterial, and a small number of bacterial species have been consistently associated with periodontitis, including bacteroides forsythus and porphyromonas gingivalis. comparatively little attention has been paid to the identification of health-associated and potentially beneficial bacterial species that may reside in the gingival sulcus. the purpose of the present study was to examine the relati ... | 2002 | 11880400 |
| maternal periodontitis and prematurity. part ii: maternal infection and fetal exposure. | clinical data from the first 812 deliveries from a cohort study of pregnant mothers entitled oral conditions and pregnancy (ocap) demonstrate that both antepartum maternal periodontal disease and incidence/progression of periodontal disease are associated with preterm birth and growth restriction after adjusting for traditional obstetric risk factors. in the current study we present measures of maternal periodontal infection using whole chromosomal dna probes to identify 15 periodontal organisms ... | 2001 | 11887461 |
| genome sequence and analysis of the oral bacterium fusobacterium nucleatum strain atcc 25586. | we present a complete dna sequence and metabolic analysis of the dominant oral bacterium fusobacterium nucleatum. although not considered a major dental pathogen on its own, this anaerobe facilitates the aggregation and establishment of several other species including the dental pathogens porphyromonas gingivalis and bacteroides forsythus. the f. nucleatum strain atcc 25586 genome was assembled from shotgun sequences and analyzed using the ergo bioinformatics suite (http://www.integratedgenomics ... | 2002 | 11889109 |
| distribution of erm(f) and tet(q) genes in 4 oral bacterial species and genotypic variation between resistant and susceptible isolates. | bacteroides forsythus, porphyromonas gingivalis and prevotella intermedia are gram-negative anaerobic bacteria that are currently considered potential periopathogens. prevotella nigrescens has recently been separated from p. intermedia and its rôle in periodontitis is unknown. the erm(f) gene codes for an rrna methylase, conferring resistance to macrolides, lincosamides and streptogramin b (mlsb), and the tet(q) gene for a ribosomal protection protein, conferring resistance to tetracycline. the ... | 2002 | 11895543 |
| clinical and microbiological studies of periodontal disease in sjögren syndrome patients. | little is known about the periodontal status of patients with sjögren's syndrome (ss), a chronic inflammatory autoimmune disease characterized by xerophthalmia and xerostomia. the aim of the present study was to evaluate whether the periodontal status of ss patients, in terms of clinical and microbiological parameters, differs from systemically healthy age- and gender-matched controls. | 2002 | 11908470 |
| periodontopathic bacteria in young healthy subjects of different ethnic backgrounds in los angeles. | the present study determined risk indicators for oral colonization by actinobacillus actinomycetemcomitans, porphyromonas gingivalis, bacteroides forsythus, and treponema denticola in 150 children and adolescents, 4 to 16 years of age, living in los angeles, california. | 2002 | 11922257 |
| bacteroides forsythus hemagglutinin is inhibited by n-acetylneuraminyllactose. | bacteroides forsythus, which has been recognized as a pathogen associated with periodontitis, produces a hemagglutinin. the hemagglutinin was localized in the envelope of b. forsythus. the hemagglutinating activity was inhibited by lactose at concentrations as low as 1 mm, and by l-arginine and l-lysine at concentrations of 100 mm. n-acetylneuraminyllactose (neuac-lactose) was at least 100 times more potent an inhibitor than lactose, as it completely inhibited the hemagglutination at concentrati ... | 2002 | 11929561 |
| clinical, genetic and microbiological findings in a brazilian family with aggressive periodontitis. | aggressive periodontitis comprises a group of rapidly progressive forms of periodontitis. besides bacteria, a high level of subject susceptibility must be involved in the expression of disease. in the present study, we report the clinical, microbiological and genetic profile of a 14-individual family with aggressive periodontitis. | 2002 | 11940143 |
| [identification of periodontopathic bacteria dna from periodontitis-involved gingival tissue using a pcr method]. | the purpose of this study was to determine the presence of periodontopathic bacteria dna in the granulation tissue of periodontally involved gingival tissue. forty periodontitis patients were examined. subgingival plaque and saliva samples were collected from the patients before surgery. then, granulation tissue was also collected during surgery. another 20 patients, who had more than 4 mm in probing pocket depth, were also examined as a control. they received only initial treatment without peri ... | 2002 | 11968834 |
| effect of fusobacterium nucleatum on the t and b cell responses to porphyromonas gingivalis in a mouse model. | t cell cytokine profiles and specific serum antibody levels in five groups of balb/c mice immunized with saline alone, viable fusobacterium nucleatum atcc 25586, viable porphyromonas gingivalis atcc 33277, f. nucleatum followed by p. gingivalis and p. gingivalis followed by f. nucleatum were determined. splenic cd4 and cd8 cells were examined for intracytoplasmic interleukin (il)-4, interferon (ifn)-gamma and il-10 by dual colour flow cytometry and the levels of serum anti-f. nucleatum and anti- ... | 2002 | 11985513 |
| serum igg antibody response to periodontal pathogens in minority populations: relationship to periodontal disease status and progression. | differences in periodontal disease prevalence, severity, subgingival microflora and host immune response have been reported for various ethnic/racial groups, which implies that risk factors for destructive periodontal disease progression may also vary in these populations. as it is possible that these differences may be due to confounding variables other than ethnicity/race, we have measured serum igg antibody response to six periodontal pathogens, and compared these data with microbiological, c ... | 2002 | 12009183 |
| reclassification of bacteroides forsythus (tanner et al. 1986) as tannerella forsythensis corrig., gen. nov., comb. nov. | the characteristics of the fusiform species bacteroides forsythus, isolated from human periodontal pockets, were examined. 165 rdna sequence analysis confirmed that b. forsythus was not a species within the genus bacteroides sensu stricto. although b. forsythus was phylogenetically related to bacteroides distasonis and bacteroides merdae in the phylogenetic tree, the ratio of anteiso-15:0 to iso-15:0 in whole-cell methanolysates of b. forsythus was different from those of b. distasonis, b. merda ... | 2002 | 12054248 |
| direct amplification of rrna gene sequences for identification of selected oral pathogens in root canal infections. | the purpose of this study was to assess the prevalence of selected oral pathogens in root canal infections and their relationship with symptoms using a highly sensitive technique, the polymerase chain reaction. | 2002 | 12059935 |
| the relationship between the presence of periodontopathogenic bacteria in saliva and halitosis. | to evaluate the association between the presence of periodontal pathogenic bacteria in saliva and halitosis in mouth air. | 2002 | 12090455 |
| [cloning and sequence analysis of a sialidase gene (siahi) from bacteroides forsythus atcc 43037]. | bacteroides forsythus is known as a periodontopathogen associated with periodontitis, and it produces a tripsin-like protease, cell-death inducing factor, and sialidase (neuraminidase), as putative virulence factors. the purpose of this study was to clone the sialidase gene from b. forsythus atcc 43037, and to analyze the biological characteristics. a positive clone (phi-1) was successfully isolated, among a total of 455 recombinant clones, using a filter paper sialidase assay with the fluorogen ... | 2002 | 12136659 |
| [detection of periodontal pathogenic microorganisms in atheromatous plaque. preliminary results]. | recent studies suggest that chronic infections, including those associated with periodontitis, increase the risk for coronary vascular disease. we hypothesize that oral microorganisms including periodontal bacterial pathogens enter the blood stream during transient bacteremias where they may play a role in the development and progression of atherosclerosis. | 2002 | 12149943 |
| microbiological findings and host response in patients with peri-implantitis. | the aim of the present study was to characterise microbiota and inflammatory host response around implants and teeth in patients with peri-implantitis. we included 17 partly edentulous patients with a total of 98 implants, of which 45 showed marginal bone loss of more than three fixture threads after the first year of loading. nineteen subjects with stable marginal tissue conditions served as controls. oral hygiene, gingival inflammation, and probing pocket depth were evaluated clinically at tee ... | 2002 | 12175371 |
| clinical and microbiological analysis of periodontally diseased sites after renal transplant. | this study compared the clinical and microbiological status of periodontally diseased sites in 42 patients who had a renal transplant and were undergoing immunosuppressive therapy (21 taking azathioprin and corticosteroids [az-c] and 21 taking cyclosporin-a [cy-a] with those of 21 systemically healthy matched controls. probing pocket depth (ppd), bleeding on probing (bop) and gingival hyperplasia (gh) were measured at 339 sites. subgingival plaque samples were analyzed for the presence of porphy ... | 2002 | 12240891 |
| stress and the periodontal diseases: effects of catecholamines on the growth of periodontal bacteria in vitro. | microorganisms possess the ability to recognize hormones within the host and utilize them to adapt to their surroundings. noradrenaline and adrenaline, which are released during human stress responses, may act as environmental cues to alter the growth of individual organisms within subgingival biofilms. the aims of this study were to modify, for anaerobic culture, existing methodology used in determining microorganism catecholamine responses and to investigate the growth responses to noradrenali ... | 2002 | 12354211 |
| initial effect of controlled release chlorhexidine on subgingival microorganisms. | little or no data exist on the ability of subgingival application of periochip (2.5 mg chlorhexidine gluconate in a biodegradable chip; astra pharmaceuticals, westborough, ma, usa) to suppress periodontopathic microorganisms. the present study compared the subgingival microbiota of periodontitis sites receiving the chlorhexidine chip plus scaling and root planing (sc/rp) or sc/rp alone. | 2002 | 12366861 |
| transmission of periodontal disease-associated bacteria from teeth to osseointegrated implant regions. | the presence of periodontopathic bacteria is a risk factor for peri-implantitis. the present study examined colonization by periodontopathic bacteria and their transmission from periodontal pockets to osseointegrated implant sulcus. | 2002 | 12381070 |
| antibacterial activity of moxifloxacin against periodontal anaerobic pathogens involved in systemic infections. | the in vitro activity of moxifloxacin was compared with that of penicillin g, amoxycillin/clavulanate, cefoxitin, erythromycin, clindamycin and metronidazole against 158 isolates associated with periodontal infections. mic(50)/mic(90) values of moxifloxacin were respectively 0.06/0.5 mg/l for porphyromonas gingivalis (35), for prevotella spp. (28) and actinomyces spp. (35), 0.12/0.25 mg/l for fusobacterium nucleatum (20) and 0.06/0.12 mg/l for peptostreptococcus spp. (30). the minimum inhibitory ... | 2002 | 12458140 |
| comparison of 16s rdna-based pcr and checkerboard dna-dna hybridisation for detection of selected endodontic pathogens. | molecular methods have been used recently to investigate the bacteria encountered in human endodontic infections. the aim of the present study was to compare the ability of a 16s rdna-based pcr assay and checkerboard dna-dna hybridisation in detecting actinobacillus actinomycetemcomitans, bacteroides forsythus, peptostreptococcus micros, porphyromonas endodontalis, por. gingivalis and treponema denticola directly from clinical samples. specimens were obtained from 50 cases of endodontic infectio ... | 2002 | 12466407 |
| porphyromonas gingivalis, bacteroides forsythus and other putative periodontal pathogens in subjects with and without periodontal destruction. | bacteria play an essential role in the pathogenesis of destructive periodontal disease. it has been suggested that not all bacteria associated with periodontitis may be normal inhabitants of a periodontally healthy dentition. in particular, porphyromonas gingivalis and actinobacillus actinomycetemcomitans have been isolated infrequently from subjects without periodontitis. the aim of the present study was to compare prevalence and proportions of a number of periodontal bacteria in periodontitis ... | 2002 | 12472995 |
| microbiological markers for prediction and assessment of treatment outcome following non-surgical periodontal therapy. | actinobacillus actinomycetemcomitans, porphyromonas gingivalis, and bacteroides forsythus are considered major putative periodontal pathogens. however, it remains unclear what combinations or what levels of these bacteria influence treatment outcome. the purpose of the present study was to establish useful pathogenic markers for prediction and assessment of treatment outcome following scaling and root planing (srp). | 2002 | 12479627 |
| the relationship of oral malodor in patients with or without periodontal disease. | halitosis has been correlated with the concentration of volatile sulfur compounds (vsc) produced in the oral cavity by metabolic activity of bacteria colonizing the periodontal area and the dorsum of the tongue. the aim of this study was to determine whether there is some relationship between the presence of n-benzoyl-dl-arginine-2-napthylamide (bana)-positive species treponema denticola, porphyromonas gingivalis, and bacteroides forsythus and clinical and oral malodor parameters. | 2002 | 12479639 |
| similarity of the oral microbiota of pre-school children with that of their caregivers in a population-based study. | this study evaluated the similarity between the oral microbiota of young children and that of their adult caregivers. oral samples from children (174 dentate and 18 pre-dentate) aged 6-36 months and their caregivers in saipan were assayed using a dna probe assay. many species including streptococcus mutans, streptococcus sobrinus, actinomyces species, campylobacter rectus, fusobacterium nucleatum, prevotella intermedia, and porphyromonas gingivalis were detected in dentate and pre-dentate childr ... | 2002 | 12485330 |
| microbiota around root-form endosseous implants: a review of the literature. | although high success rates for root-form endosseous implants have been reported, failures occasionally occur, and these implants must be removed. at least 10% of the failures have been suggested to be the result of peri-implantitis. there is some evidence that periodontal pathogens, mainly those belonging to the group of gram-negative anaerobic rods, play a role in the etiology of peri-implantitis. this article provides an overview of the literature associated with common peri-implant microbiol ... | 2002 | 12507243 |
| igg subclass specific antibody response to periodontopathic organisms in hiv-positive patients. | we previously reported an increased rate of progression of periodontal disease over an 18-month period in human immunodeficiency virus (hiv)-positive subjects compared to controls. the mechanism for disease progression and rapid tissue loss was unknown. data on the microbiological studies failed to show any significant difference in the microbial characteristics of the periodontal lesions in hiv-positive patients compared to hiv-negative controls. immunological analysis had identified neutrophil ... | 2002 | 12546094 |
| determination of eight selected periodontal pathogens in the subgingival plaque of maxillary first molars in japanese school children aged 8-11 years. | to prevent the onset or progression of periodontitis, we must understand when periodontal pathogens are first harbored and how they develop the biofilm that causes periodontal disease. the purpose of this study was to determine the relationship between clinical status and selected periodontal pathogens in subgingival plaque in school children. this study was conducted with 95 school children, 8-11 years old. the presence and distribution of eight selected periodontal pathogens sampled from the m ... | 2003 | 12558934 |
| high prevalence of helicobacter pylori detected by pcr in the oral cavities of periodontitis patients. | helicobacter pylori has been associated with the development of peptic ulcers and gastric cancer. although it may be transmitted through the oral cavity, it is unknown whether the oral cavity acts as a permanent reservoir for this bacterium. the purpose of this study was to use nested polymerase chain reaction (pcr) to clarify whether the oral cavity acts as a reservoir for h. pylori. | 2003 | 12593608 |
| faropenem, a new oral penem: antibacterial activity against selected anaerobic and fastidious periodontal isolates. | the in vitro activity of faropenem, an oral penem, was compared with those of penicillin, co-amoxiclav, cefoxitin, clindamycin, erythromycin and metronidazole against 106 isolates of anaerobic pathogens involved in systemic infections. the organisms tested comprised porphyromonas gingivalis (29), prevotella spp. (eight), prevotella melaninogenica (seven), prevotella intermedia (five), actinomyces spp. (25), fusobacterium nucleatum (14), peptostreptococcus spp. (11), bacteroides ureolyticus (five ... | 2003 | 12615878 |
| vaccination and periodontitis: myth or reality. | in most industrialised countries approximately 15% of the population has enhanced risk for moderate to severe periodontitis. the disease is caused by infection by gram-negative, anaerobic bacteria including porphyromonas gingivalis and bacteroides forsythus. there is evidence that p. gingivalis is a key pathogen. using ligature-induced periodontitis in the non-human primate macaca fascicularis as a model, we immunised 10 animals using intact killed p. gingivalis and saf-m adjuvant and 10 control ... | 2000 | 12666959 |
| accumulation of methylglyoxal in the gingival crevicular fluid of chronic periodontitis patients. | methylglyoxal (mg), a toxic product of cellular metabolism, is elevated in tissues and fluids in a number of human diseases. a cross-sectional study was undertaken to determine whether mg accumulates in the gingival crevicular fluid (gcf) of chronic periodontitis patients. | 2003 | 12694437 |
| guided tissue regeneration using a polylactic acid barrier. part i: environmental effects on bacterial colonization. | the purpose of this study was to assess the dynamics of bacterial colonization in intra-osseous defects following guided tissue regeneration (gtr) therapy using a resorbable barrier. | 2003 | 12702107 |
| a rapid dna probe test compared to culture methods for identification of subgingival plaque bacteria. | there has been a significant amount of interest in developing a more rapid and cost-effective test to identify bacterial pathogens in plaque. dna probe technology may meet both these objectives, it is more rapid and cost-effective when compared to culture methods. the purpose of this study was to compare an automated dna probe test with classical culture methods for identifying bacteroides forsythus and porphyromonas gingivalis in subgingival plaque of patients with adult periodontitis. subgingi ... | 2003 | 12702112 |
| ovine periodontitis as a potential model for periodontal studies. cross-sectional analysis of clinical, microbiological, and serum immunological parameters. | : to investigate infection and host immunity patterns in sheep with naturally occurring "broken-mouth" periodontitis. | 2003 | 12702113 |
| herpesviral-bacterial interactions in aggressive periodontitis. | human cytomegalovirus, epstein-barr virus and herpesvirus co-infections occur with significantly higher frequency in actively progressing than in stable periodontitis sites of adolescents and young adults. also, periodontal presence of cytomegalovirus and epstein-barr virus is associated with increased occurrence of subgingival porphyromonas gingivalis, bacteroides forsythus, dialister pneumosintes, prevotella intermedia, prevotella nigrescens, treponema denticola and actinobacillus actinomycete ... | 2003 | 12716334 |
| fluorescence in situ hybridization (fish) for direct visualization of bacteria in periapical lesions of asymptomatic root-filled teeth. | whether micro-organisms can live in periapical endodontic lesions of asymptomatic teeth is under debate. the aim of the present study was to visualize and identify micro-organisms within periapical lesions directly, using fluorescence in situ hybridization (fish) in combination with epifluorescence and confocal laser scanning microscopy (clsm). thirty-nine periapical lesions were surgically removed, fixed, embedded in cold polymerizing resin and sectioned. the probe eub 338, specific for the dom ... | 2003 | 12724371 |
| humoral immune responses to s-layer-like proteins of bacteroides forsythus. | bacteroides forsythus is one of the important periodontopathic bacteria, and this microorganism is known to have an s-layer outside the outer membrane. the s-layer-like antigens were recently isolated from b. forsythus, and they were found to be 270- and 230-kda proteins in the envelope fraction. in this study, these proteins were confirmed to be specific to b. forsythus by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and they were clearly recognized by sera from patients with adul ... | 2003 | 12738635 |
| accidentally induced periodontitis in primary dentition: longitudinal examinations of periodontal bacteria and clinical conditions. | periodontitis is very rare in the primary dentition although it can be accidentally induced in young children. the purpose of this study was to describe a case of periodontitis in a 4-year-old child, which was accidentally induced by insertion of small plastic tubes into the dental cervix of the primary incisors during play, and to discuss the clinical, radiographic, and microbiological findings. removal of the plastic tubes resulted in resolution of the periodontal condition. prevotella nigresc ... | 2003 | 12752919 |
| can presence or absence of periodontal pathogens distinguish between subjects with chronic and aggressive periodontitis? a systematic review. | the purpose of this study was to determine to what extent the presence or absence of periodontal pathogens can distinguish between subjects with chronic and aggressive periodontitis. | 2002 | 12787203 |
| is periodontitis associated with an increased risk of coronary heart disease and preterm and/or low birth weight births? | the objective of this systematic review was to determine whether periodontal disease is associated with an increased risk for coronary heart disease (chd) and preterm and/or low birth weight deliveries (plbw). a literature search was performed to identify cross-sectional, case-control, and cohort studies as well as clinical trials addressing different aspects of periodontal disease (clinical, microbial, immunological) and clinical outcomes of chd or plbw. the periodontitis-chd association was ev ... | 2002 | 12787204 |
| subgingival microbiota levels and their associations with periodontal status at the sampled sites in an adult sudanese population using miswak or toothbrush regularly. | little information is available on the effect of miswak use on gingival microbiota. we assessed levels of 28 oral bacteria in subgingival plaque of adult sudanese miswak (n = 38) and toothbrush users (n = 36) age range 20-53 years (mean 34.6 years) to study associations between these bacteria, oral hygiene method, and periodontal status at the sampled sites. a pooled subgingival plaque sample from 6 probing sites of 1 selected tooth in each jaw was obtained from each subject. whole genomic dna p ... | 2003 | 12790510 |
| five-year maintenance follow-up of early-onset periodontitis patients. | the purpose of this study was to evaluate the clinical and microbiological status of patients with early-onset or aggressive periodontitis (eop) who had received supportive periodontal care (spc) every 3-6 months for a period of 5 years, following active periodontal treatment. | 2003 | 12795796 |
| pcr methodology as a valuable tool for identification of endodontic pathogens. | this paper reviews the principles of polymerase chain reaction (pcr) methodology, its application in identification of endodontic pathogens and the perspectives regarding the knowledge to be reached with the use of this highly sensitive, specific and accurate methodology as a microbial identification test. | 2003 | 12799118 |
| bacteroides forsythus in primary endodontic infections as detected by nested pcr. | the purpose of this study was to investigate the prevalence of bacteroides forsythus in primary endodontic infections using a species-specific nested polymerase chain reaction assay. samples were collected from 50 teeth having carious lesions, necrotic pulps, and different forms of periradicular diseases. dna extracted from the samples was initially amplified using universal 16s rdna primers. a second round of amplification used the first polymerase chain reaction products to detect a specific f ... | 2003 | 12814221 |
| distribution of bacteroides forsythus genotypes in a japanese periodontitis population. | bacteroides forsythus is an important pathogen in periodontal diseases and has been associated with advanced and refractory periodontitis. the difficulties associated with culturing this species have meant that the distribution and pathogenic mechanisms of b. forsythus remain unclear. in this study, the arbitrarily primed polymerase chain reaction (ap-pcr) method was used to investigate the genotype distribution of b. forsythus in a japanese periodontitis population, as well as the relationship ... | 2003 | 12823795 |
| lethal photosensitization of periodontal pathogens by a red-filtered xenon lamp in vitro. | the ability of helium-neon (he-ne) laser irradiation of a photosensitizer to induce localized phototoxic effects that kill periodontal pathogens is well documented and is termed photodynamic therapy (pdt). | 2003 | 12828662 |
| effect of smoking and periodontal treatment on the subgingival microflora. | the effect of smoking on the prevalence of periodontal pathogens after periodontal treatment is still not clear. some studies found no effect of the smoking status on the prevalence of periodontal pathogens after therapy, whereas others did. the aim of this retrospective study was to investigate the influence of smoking on the treatment of periodontitis and the composition of the subgingival microflora. | 2003 | 12834497 |
| the benzoyl-dl arginine-naphthylamide (bana) test and polymerase chain reaction measurement of pathogenic bacteria can assess the severity of periodontal disease. | the benzoyl-dl arginine-naphthylamide (bana) test for detecting digesting peptidase and polymerase chain reaction (pcr) measurement of pathogenic bacteria were performed in 15 patients with periodontal disease. the number of porphyromonas gingivalis, bacteroides forsythus and treponema denticola, which are the most potent accelerators of alveolar bone resorption, were determined. attachment loss and the bana test showed significant close correlations with the number of pathogenic bacteria as wel ... | 2003 | 12854883 |
| positive and negative bacterial associations involving dialister pneumosintes in primary endodontic infections. | dialister pneumosintes is an anaerobic gram-negative rod that has been recently implicated as a candidate endodontic pathogen. in this study, samples taken from abscessed teeth and infected root canals associated with asymptomatic or symptomatic periradicular lesions were examined for the occurrence of bacterial associations involving d. pneumosintes. dna was extracted from the samples, and the presence of d. pneumosintes and 16 other bacterial species was determined by means of species-specific ... | 2003 | 12877258 |
| detection of tannerella forsythensis (bacteroides forsythus) and porphyromonas gingivalis by polymerase chain reaction in subjects with different periodontal status. | the aim of this study was to determine the prevalence of tannerella forsythensis (formerly bacteroides forsythus) and porphyromonas gingivalis in subgingival plaque samples by using polymerase chain reaction (pcr), and to assess the relationship of these bacteria with different categories of periodontal disease and health. | 2003 | 12886989 |
| subgingival microflora in turkish patients with periodontitis. | no information exists on periodontitis-associated subgingival microbiota from turkey. we determined the occurrence, interspecies relationships, and clonal characteristics for a group of periodontal bacteria in a turkish study population. | 2003 | 12886990 |
| cloning and expression of alpha-d-glucosidase and n-acetyl-beta-glucosaminidase from the periodontal pathogen, tannerella forsythensis (bacteroides forsythus). | screening a genomic library of tannerella forsythensis (bacteroides forsythus), using synthetic substrates conjugated to a fluorogen, 4-methylumbelliferone identified two glycosidase genes, which encode alpha-d-glucosidase and n-acetyl-beta-d-glucosaminidase, respectively. the alpha-d-glucosidase has a mr of 81,141 and is homologous to an alpha-d-glucosidase from bacteroides thetaiotaomicron. the n-acetyl-beta-d-glucosaminidase has a mr of 87,787 and is homologous to an n-acetyl-beta-d-glucosami ... | 2003 | 12930523 |
| localized aggressive periodontitis in primary dentition: a case report. | a 5-year-old japanese boy presented with persistent gingival inflammation and severe mobility of the right lower primary incisors. due to severe alveolar bone loss and a deep periodontal pocket (5 mm), the incisors were extracted at the second visit. | 2003 | 12931770 |
| endpoint quantitative pcr assays for bacteroides forsythus, porphyromonas gingivalis, and actinobacillus actinomycetemcomitans. | conventional polymerase chain reaction (pcr) assays for periodontal pathogens are so sensitive that they detect infections of no clinical significance. quantitative pcr (qpcr) may provide a solution to this problem. however, most qpcr systems require expensive real-time thermal cyclers. | 2003 | 12941069 |
| potential role of vascular endothelial growth factor, interleukin-8 and monocyte chemoattractant protein-1 in periodontal diseases. | host-mediated immunoinflammatory pathways activated by bacteria lead to destruction of the periodontal connective tissues and alveolar bone. the objective of this study was to elucidate the activation of the inflammatory processes in periodontal disease by quantitative assessment of cytokines and periodontopathogens. gingival crevicular fluids (gcf) and subgingival plaque samples were collected from patients with chronic periodontitis and gingivitis and from periodontally healthy sites. vascular ... | 2003 | 12962428 |
| a morphological and immunolabeling study of freeze-substituted bacteroides forsythus. | we used a rapid freezing and freeze-substitution technique without glutaraldehyde and oso4 fixation for the electron microscopic immunocytochemical demonstration of the surface structure of bacteroides forsythus, an anaerobic gram-negative periodontopathogen. cells were applied to pieces of filter paper and freeze-substituted by plunge-freezing in liquid propane, substituted in methanol containing 0.5% uranyl acetate, and infiltrated with lr white resin. the membrane ultrastructure of b. forsyth ... | 2003 | 14533849 |
| distribution of periodontal pathogens in korean aggressive periodontitis. | microbial associations in aggressive periodontitis versus different ethnic origins are substantially unknown. we undertook this study to determine the prevalence of seven putative periodontopathogens in korean patients and to evaluate microbial differences in localized and generalized aggressive periodontitis patients. | 2003 | 14584866 |
| flavobacterium johnsoniae gldh is a lipoprotein that is required for gliding motility and chitin utilization. | cells of flavobacterium johnsoniae move rapidly over surfaces by gliding motility. the mechanism of this form of motility is not known. six genes (glda, gldb, gldd, gldf, gldg, and ftsx) that are required for gliding have been described. tn4351 mutagenesis was used to identify another gene, gldh, which is required for cell movement. gldh mutants formed nonspreading colonies, and individual cells lacked the cell movements and ability to propel latex spheres along their surfaces that are character ... | 2003 | 14594839 |
| immunoglobulin g and a antibody responses to bacteroides forsythus and prevotella intermedia in sera and synovial fluids of arthritis patients. | the objective of the present study was to investigate immunoglobulin g (igg) and iga antibody immune responses to porphyromonas gingivalis, prevotella intermedia, bacteroides forsythus, and candida albicans in the sera of patients with rheumatoid arthritis (ra), the synovial fluid (sf) of patients with ra (ra-sf samples), and the sf of patients without ra (non-ra-sf samples). an enzyme-linked immunosorbent assay was used to determine igg and iga antibody levels in 116 serum samples from patients ... | 2003 | 14607865 |
| cloning of the tannerella forsythensis (bacteroides forsythus) siahi gene and purification of the sialidase enzyme. | tannerella forsythensis (previously named bacteroides forsythus) is a gram-negative, anaerobic, fusiform bacterium that is a primary or secondary aetiological agent in periodontal disease in humans. t. forsythensis expresses several putative virulence factors, including a sialidase; however, there has been no molecular genetic characterization of this enzyme. a sialidase clone (phi-1) was screened from a total of 455 recombinant clones of a genomic dna library using the 2'- (4-methylumbelliferyl ... | 2003 | 14614069 |
| the effects of extracts from periodontopathic bacteria on human periodontal fibroblasts stimulated with mineralization supplements. | bacterial effects on in vitro mineralization of human periodontal fibroblasts (hpf) have not yet been examined in great detail. in our study, we investigated the effects of soluble extracts of the periodontopathic bacteria porphyromonas gingivalis, bacteroides forsythus and, treponema denticola on cell proliferation, mineralization, as well as on osteoblastic markers present in hpf cultured in vitro, such as alkaline phosphatase (alp) activity and collagen content. periodontal fibroblasts stimul ... | 2003 | 14650577 |
| prevalence of periodontopathic bacteria in aggressive periodontitis patients in a japanese population. | actinobacillus actinomycetemcomitans is considered a major etiologic agent of aggressive periodontitis. other periodontopathic bacteria such as porphyromonas gingivalis are also suspected of participating in aggressive periodontitis, although the evidence is controversial. the aim of the present study was to investigate the prevalence of periodontopathic bacteria and to clarify the microbiological features of aggressive periodontitis in japanese patients. | 2003 | 14653392 |
| proposal to conserve the adjectival form of the specific epithet in the reclassification of bacteroides forsythus tanner et al. 1986 to the genus tannerella sakamoto et al. 2002 as tannerella forsythia corrig., gen. nov., comb. nov. request for an opinion. | with reference to the first principle of the international code of nomenclature of bacteria, which emphasizes stability of names, it is proposed that the original adjectival form of the specific epithet be conserved in the reclassification of bacteroides forsythus to the new genus tannerella. thus, tannerella forsythensis sakamoto et al. 2002 should be tannerella forsythia sakamoto et al. 2002 corrig., gen. nov., comb. nov., and we put forward a request for an opinion to the judicial commission ... | 2003 | 14657155 |