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[action of external factors on the development of the genital apparatus of field-mice (apodemus sylvaticus l.)]. 195014792807
[active spermatogenesis, in winter, in field-mice (apodemus sylvaticus l) raised in outdoor cage]. 195114896592
parasite aggregations in host populations using a reformulated negative binomial model.the negative binomial distribution model is reformulated and used to demarcate a host population at a specific level of infection by defining an attribute spanning a range of parasite aggregations. the upper limit of the range specifies the boundary for the classification of the host population and provides a technique to determine the cumulative probability at any level of parasite infection to a high degree of accuracy. this approach also leads to the evaluation of the k parameter, i.e. an inv ...200414972038
[puumala and dobrava viruses in the northeastern and central regions of bosnia].bosnia and herzegovina has been known as a highly endemic region for hantavirus infections for more than 50 years. previous studies have shown that at least two different hantaviruses, the murine dobrava (dob) and avricoline puumala (puu) viruses, each carried by a different rodent species, have been circulating in the area. however, there is little information on rodent population density fluctuations in bosnia over the past years as well as on the ratio of puumala to dobrava infection in human ...200315011464
[what is new in the epidemiologic characteristics of hemorrhagic fever with renal syndrome in croatia?].the aim was to describe epidemiologic characteristics of hemorrhagic fever with renal syndrome in croatia.200315011468
palatability of dead earthworms and slugs to the wood mouse (apodemus sylvaticus) and the potential for secondary poisoning. 200415058654
polychlorinated biphenyls in small mammals from contaminated landfill sites.pcbs in small mammals living in a contaminated landfill site varied in both concentration and congener composition, reflecting both the feeding strategy of each species and the chlorination of the congeners. body concentrations of sigmapcb on a 1:1:1 arochlor (1242:1254:1260) basis gave a rank order of sorex araneus > apodemus sylvaticus > microtus agrestis. comparisons with data for other pcb-contaminated sites suggest that the sigmapcb values in s. araneus from the landfill site may be of suff ...199615091398
predicting cadmium, lead and fluoride levels in small mammals from soil residues and by species-species extrapolation.the effects of heavy metals on wild mammals are often assessed by analysing residues in body organs. this paper reviews published studies to determine whether cadmium (cd), lead (pb) and fluoride (f) residues in small mammals can be predicted directly from residues in soil or, when this is not possible, from residues in other species. it was found that residues in soil could be used to predict cd and pb concentrations in small mammals. there were significant (p < 0.05) relationships between cd r ...199515091546
arsenic contamination in wood mice (apodemus sylvaticus) and bank voles (clethrionomys glareolus) on abandoned mine sites in southwest britain.arsenic can be highly toxic to mammals but there is relatively little information on its transfer to and uptake by free-living small mammals. the aim of this study was to determine whether intake and accumulation of arsenic by wild rodents living in arsenic-contaminated habitats reflected environmental levels of contamination and varied between species, sexes and age classes. arsenic concentrations were measured in soil, litter, wood mice (apodemus sylvaticus) and bank voles (clethrionomys glare ...200015092868
dioxin and furan residues in wood mice (apodemus sylvaticus) following a large scale polyvinyl chloride (pvc) fire.a forest ecosystem was contaminated as a result of a fire involving 600 t of pvc. a wide range of 2,3,7,8-substituted dioxin and furan congeners were elevated (by up to 4-fold) on soil adjacent to the factory compared to a site 200 m from the factory perimeter. livers of wood mice (apodemus sylvaticus) caught on these areas were also analysed for dioxins and furans. toxic equivalents (teqs) were 9-fold higher in wood mice caught on the site 10 m from the factory perimeter compared with the site ...199715093358
biochemical effect evaluation of perfluorooctane sulfonic acid-contaminated wood mice (apodemus sylvaticus).wood mice (apodemus sylvaticus) were captured at blokkersdijk, a nature reserve in the immediate vicinity of a fluorochemical plant in antwerp, belgium, and at galgenweel, 3 kilometers farther away. the liver perfluorooctane sulfonic acid (pfos) concentrations in the blokkersdijk mice were extremely high (0.47-178.55 micro g/g wet weight). perfluorononanoic, perfluorodecanoic, perfluoroundecanoic, and perfluorododecanoic acids were found sporadically in the liver tissue of the blokkersdijk mice. ...200415121511
sexual transmission of a nematode parasite of wood mice (apodemus sylvaticus)?sexual transmission occurs commonly in microparasites such as viruses and bacteria, but this is an unusual transmission route for macroparasites. here we present evidence which suggests that a nematode parasite of wood mice (apodemus sylvaticus) may be sexually transmitted and we have classified the nematode using molecular data. wood mice were collected annually in the course of work on their reproductive physiology. larval nematodes were found in the epididymides of 19.6% of males. it seems li ...200415180324
chromosome painting in the long-tailed field mouse provides insights into the ancestral murid karyotype.we report on the hybridization of mouse chromosomal paints to apodemus sylvaticus, the long-tailed field mouse. the mouse paints detected 38 conserved segments in the apodemus karyotype. together with the species reported here there are now six species of rodents mapped with mus musculus painting probes. a parsimony analysis indicated that the syntenies of nine m. musculus chromosomes were most likely already formed in the muroid ancestor: 3, 4, 7, 9, 14, 18, 19, x and y. the widespread occurren ...200415237228
so close and so different: comparative phylogeography of two small mammal species, the yellow-necked fieldmouse (apodemus flavicollis) and the woodmouse (apodemus sylvaticus) in the western palearctic region.in europe, concordant geographical distribution among genetic lineages within different species is rare, which suggests distinct reactions to quaternary ice ages. this study aims to determine whether such a discrepancy also affects a pair of sympatric species, which are morphologically and taxonomically closely related but which have slight differences in their ecological habits. the phylogeographic structures of two european rodents, the yellow-necked fieldmouse (a. flavicollis) and the woodmou ...200515329664
evolution of mhc-drb class ii polymorphism in the genus apodemus and a comparison of drb sequences within the family muridae (mammalia: rodentia).allelic diversity at major histocompatibility complex (mhc) genes is thought to be maintained by balancing selection over long periods of time, even across multiple speciation events. trans-species sharing of mhc alleles among genera has been supported by many studies on mammals and fish, but in rodents, the results are ambiguous. we investigated natural levels of mhc- drb variability and evolutionary processes in the wood mouse (apodemus sylvaticus) and the yellow-necked mouse (apodemus flavico ...200415351919
the helminth community of the wood mouse, apodemus sylvaticus, in the sierra espuna, murcia, spain.the helminth community of the wood mouse, apodemus sylvaticus, in the sierra espuna was characterized after a complete analysis of its helminth community component and infracommunity structure relative to host age, sex and year of capture. the helminth community comprised 13 species: one trematode, four cestodes and eight nematodes. the cestode pseudocatenotaenia matovi and the nematode syphacia frederici were the most prevalent and abundant helminth species, respectively. sixty four percent of ...200415469624
identification of bartonella species in rodents, shrews and cats in denmark: detection of two b. henselae variants, one in cats and the other in the long-tailed field mouse.small mammals and stray cats were trapped in two areas of north zealand, denmark, and their blood cultured for hemotrophic bacteria. bacterial isolates were recovered in pure culture and subjected to 16s rdna gene sequencing. bartonella species were isolated from five mammalian species: b. grahamii from microtus agrestis (field vole) and apodemus flavicollis (yellow-necked field mouse); b. taylorii from m. agrestis, a. flavicollis and a. sylvaticus (long-tailed field mouse); b. tribocorum from a ...200415511270
ultrastructure of the spermatozoon of the anoplocephalid cestode gallegoides arfaai (mobedi and ghadirian, 1977) tenora and mas-coma, 1978, an intestinal parasite of the wood mouse (apodemus sylvaticus linnaeus, 1758).the present work involves an ultrastructural study of the mature spermatozoon of the anoplocephalid cestode gallegoides arfaai (mobedi and ghadirian, 1977) tenora and mas-coma, 1978, obtained from the small intestine of naturally infected wood mice, apodemus sylvaticus linnaeus, 1758 (rodentia, muridae). the mature spermatozoon of g. arfaai is a filiform cell, tapered at both ends and lacking mitochondria. it is characterized by the presence of a 1,000-nm-long apical cone and two 140-nm-thick cr ...200415517383
cadmium and lead concentrations in gallegoides arfaai (cestoda: anoplocephalidae) and apodemus sylvaticus (rodentia: muridae) from spain.information on parasites of vertebrates living in terrestrial ecosystems as sentinels for heavy metal environmental pollution is scarce. the aim of the present study was to assess the concentration of cadmium and lead using the model apodemus sylvaticus/gallegoides arfaai in order to test the potential suitability of g. arfaai as a sentinel organism for lead and cadmium under natural field conditions. samples of 15 a. sylvaticus as well as whole specimens of g. arfaai were analysed for both elem ...200415538628
a parasite reveals cryptic phylogeographic history of its host.this study compares the continental phylogeographic patterns of two wild european species linked by a host-parasite relationship: the field mouse apodemus sylvaticus and one of its specific parasites, the nematode heligmosomoides polygyrus. a total of 740 base pairs (bp) of the mitochondrial cytochrome b (cyt b) gene were sequenced in 122 specimens of h. polygyrus and compared with 94 cyt b gene sequences (974 bp) previously acquired for a. sylvaticus. the results reveal partial spatial and temp ...200415615681
a comparison of wild-caught wood mice and bank voles in the intellicage: assessing exploration, daily activity patterns and place learning paradigms.our previous work has revealed very high baseline neurogenesis in the dentate gyrus of wood mice as compared particularly to bank voles; a difference which may be related to learning capacity. this study explored whether the newly-developed intellicage system could be used to compare these species in simple spatial learning paradigms. the intellicage is essentially a group-housing cage that also allows continuous automatic recording of each individual's behaviour. seven wild-caught bank voles (c ...200515639172
identification of genetic evidence for dobrava virus spillover in rodents by nested reverse transcription (rt)-pcr and taqman rt-pcr.a survey of 158 rodents caught in the czech republic identified dobrava virus sequences closely related to that of the dobrava virus type strain in apodemus sylvaticus and mus musculus rodents. the identity of a. sylvaticus was unequivocally confirmed by random amplified polymorphic dna analysis. the data seem to indicate hantavirus spillover from apodemus flavicollis to other rodents.200515695684
rapid g+ count and subpopulation assessment of the intestinal bacteria in apodemus sylvaticus and mus musculus by flow cytometry.we report a novel application of calcein-acetomethyl ester in flow cytometry for rapid estimation of the number of g+-bacteria in rodent feces (apodemus sylvaticus and mus sp.f. muridae). we also use the combined application of flow cytometry and syto-13 or sypro orange staining to count rapidly the total bacterial population and to describe bacterial subpopulations in the intestine.200415702550
phylogeography of a nematode (heligmosomoides polygyrus) in the western palearctic region: persistence of northern cryptic populations during ice ages?this study establishes the continental phylogeographical pattern of a european nematode, heligmosomoides polygyrus (dujardin, 1845; heligmosomoidea). we sequenced 687 base pairs of the mitochondrial dna (mtdna) cyt b gene for 136 individuals collected in 22 localities. the results revealed that h. polygyrus populations are separated into five major units corresponding to the italian, northern european (denmark and ireland), iberian, western european, and balkan populations. different subclades w ...200515723668
[evaluation of cytophysiological state of testis in forest voles living in the radioactively contaminated areas].we made a cytophysiological analys of testis in clethrionomus rutilus and apodemus sylvaticus inhabiting a contaminated area of the east ural radioactive trace (eurt). the study showed that in the norm these species differed in the total number of cells of spermatogenous epithelium, due to interspecific difference. in the sampling plot a concentration of 90sr in clethrionomus rutilus was 2 times higher than that in apodemus sylvaticus. maximum destructive changes in endocrine and exocrine (semin ...200515810529
seroepidemiology of borrelia burgdorferi sensu lato and anaplasma phagocytophilum in wild mice captured in northern turkey.an expedition across the asian part of the black sea coast and national parks of northern turkey was organized in the summer of 2001 to investigate the presence of borrelia burgdorferi sensu lato (s.l.), lyme borreliosis agent, and anaplasma phagocytophilum, human granulocytic ehrlichiosis, agent, in wild mice. a total of 65 apodemus flavicollis, apodemus sylvaticus, microtus epiroticus, crocidura suaveolens and mus macedonicus, were captured. two out of 22 apodemus sylvaticus specimens were ser ...200515816159
the occurrence of strongylid nematodes in the epididymides of wood mice.the recent discovery of a larval nematode in the epididymides of free-living wood mice (apodemus sylvaticus) suggests a sexual transmission of these parasites. they have been placed within the bursate nematodes (order strongylida) through 18s rdna analysis, suggesting that they are undetermined metastrongyloid nematodes. the possibility that these parasites are transmitted sexually opens an intriguing field of research because sexually transmitted metazoan parasites are known to occur mainly in ...200515927528
disruption of a host-parasite system following the introduction of an exotic host species.the potential of biological invasions to threaten native ecosystems is well recognized. here we describe how an introduced species impacts on native host-parasite dynamics by acting as an alternative host. by sampling sites across an invasion front in ireland, we quantified the influence of the introduced bank vole (clethrionomys glareolus) on the epidemiology of infections caused by flea-transmitted haemoparasites of the genus bartonella in native wood mice (apodemus sylvaticus). bartonella inf ...200515977903
[changes in liver of apodemus sylvaticus mice from east-ural radioactive territories].male microtus arvalis mice from radionuclide polluted territories in the south urals (90sr activity of ground--0.2, 2, 500, 800 ci/km2) were used. the 90sr content in a mouse bony skeleton was determined. carbohydrate, energy and protein metabolism, lipid peroxidation processes in liver were studied. the intensification of protein and carbohydrate enzymes. on the increase of antioxidant activity we found the reduction of lipid peroxidation processes. the decrease of microsome oxidoreductases was ...200516080629
sexual dimorphism in metapodial and phalanges length ratios in the wood mouse.relative length of metapodials and digits is sexually dimorphic in most primates and one rodent and one bird species studied so far. recently, interest in digit ratios has increased because of their correlation with diverse physiological, psychological, and performance traits in humans. these correlations may reflect the effect of androgens during early ontogeny on digit development and their long-term organizational effects on extragenital organs. inter- and intrasexual variation in digit ratio ...200516110515
the distribution of arsenic in the body tissues of wood mice and bank voles.arsenic is accumulated by free-living small mammals, but there is little information on the resultant concentrations in different tissues other than liver and kidney. such information is important because the severity of toxicological effects may be related to the amount of arsenic accumulated in specific organs, and the availability of arsenic to predators is, in part, dependent on which tissues accumulate arsenic. the objective of this study was to quantify the arsenic concentrations and the p ...200516170450
hosts and pathogen detection for immature stages of ixodes ricinus (acari: ixodidae) in north-central spain.to determine hosts of the immature stages of a southern population of ixodes ricinus, we trapped rodents and birds in an area of north-central spain in may-june and august-september of 1998 and 1999. the most frequently trapped rodents were apodemus sylvaticus (230 specimens) and clethrionomys glareolus (99), with a larval infestation prevalence of 49% and 81%, respectively (in spring) and 21% and 41% (in summer). c. glareolus was always more heavily parasitized by larvae (mean numbers 19.8 in s ...200516323055
cadmium and lead concentrations in skrjabinotaenia lobata (cestoda: catenotaeniidae) and in its host, apodemus sylvaticus (rodentia: muridae) in the urban dumping site of garraf (spain).the present study evaluates the parasitological model constituted by the wood mouse (apodemus sylvaticus) and its intestinal cestode (skrjabinotaenia lobata) as a potential bioindicator of cd and pb in the urban dumping site of garraf near the city of barcelona (spain) and in begues (reference site). tissues and respective s. lobata specimens of 38 wood mice captured in garraf and begues were analyzed for cd and pb by means of icp-ms. higher cadmium levels in s. lobata were found only in respect ...200616376469
effects of environmental pollution on microsatellite dna diversity in wood mouse (apodemus sylvaticus) populations.ten microsatellite dna loci were surveyed to investigate the effects of heavy metal pollution on the genetic diversity and population genetic structure of seven wood mouse (apodemus sylvaticus) populations along a heavy metal pollution gradient away from a nonferrous smelter in the south of antwerp (flanders, belgium). analysis of soil heavy metal concentrations showed that soil ag, as, cd, cu, and pb decreased with increasing distance from the smelter. genetic analyses revealed high levels of g ...200516398127
metal blood levels and hematological characteristics in wood mice (apodemus sylvaticus l.) along a metal pollution gradient.the present study evaluated whether blood could be used as a nondestructive tool for monitoring metal exposure and related hematological effects in wood mice (apodemus sylvaticus l.) living along a metal pollution gradient. soil concentrations of arsenic, cadmium, copper, lead, silver, and zinc decreased with distance from the emission source. blood levels of cadmium and lead differed significantly among sites, whereas those of the other metals did not. blood levels of cadmium and lead correlate ...200616494236
transfer and accumulation of metals in a soil-diet-wood mouse food chain along a metal pollution gradient.we studied the accumulation and transfer of as, cd, cu, pb and zn in the compartments of a soil-diet-wood mouse (apodemus sylvaticus) food chain at five sites located along a metal pollution gradient. we observed a clear gradient in metal exposure at increasing distance from the smelter in all compartments of the food chain for the non-essential metals. the gradient was less clear or absent for the essential metals in acorn and mice target tissues. regression analysis showed overall strong relat ...200716782248
considerations on the sample size of wood mice used to biomonitor metals.the concentrations of various metals (zn, cu, mn and cr) in liver, kidneys and brain from specimens of the wood mouse apodemus sylvaticus captured from 5 sites were measured. two of the sites were in a restored mine dump, another in an area characterized by serpentized soils and the remaining two were control sites. the sample size required for statistical differentiation of the sampling sites was calculated from the mean values and the variability in bioaccumulation corresponding to each of the ...200616815533
genotoxicity in wood mice (apodemus sylvaticus) along a pollution gradient: exposure-, age-, and gender-related effects.we investigated the effects of environmental pollution on genetic damage in wood mice (apodemus sylvaticus) by means of the comet assay, with special attention to the role of age and gender as potential confounding variables. the present study was carried out at four sites along a pollution gradient in the vicinity of antwerp (belgium), with a nonferrous smelter as the main pollution source. we measured the concentration of heavy metals (cd, co, cr, cu, fe, mn, pb, and zn) in mouse liver and kid ...200616916035
serological survey for viral pathogens in turkish rodents.wild rodents (n = 330) were trapped around the villages of altindere and coşandere (maçka, trabzon province), ayder, ortan, and yolkiyi (camlihemşin, rize province), and bozdag (odemiş, izmir province) in northeastern and western turkey during april 2004. samples were tested for arenavirus, hantavirus, and cowpox virus (family poxviridae, genus orthopoxvirus, cpxv) antibodies by using immunofluorescence assays (ifas). antibodies against arenaviruses were found in eight of 330 (2.4%) rodents. are ...200617092901
[helminth fauna of rodents (arvicolidae and muridae) from the kampinos national park].the aim of the study was to examine the parasite fauna of rodents living in natural environment, but in close contact with human seats (small village at the area of the natural big forest).200617120995
pfos levels in the blood and liver of a small insectivorous songbird near a fluorochemical plant.perfluorooctane sulfonate (pfos) is the stable end product of the degradation of various perfluorinated compounds and is the predominant compound found in the environment and biota. pfos is a widespread environmental contaminant that is found in a great diversity of wildlife species with more elevated tissue concentrations in animals from populated and industrialized areas. in this study we determined the pfos accumulation in blood and livers of a small songbird, the great tit (parus major), in ...200717188355
by hook or by crook? morphometry, competition and cooperation in rodent sperm.sperm design varies enormously across species and sperm competition is thought to be a major factor influencing this variation. however, the functional significance of many sperm traits is still poorly understood. the sperm of most murid rodents are characterised by an apical hook of the sperm head that varies markedly in extent across species. in the european woodmouse apodemus sylvaticus (muridae), the highly reflected apical hook of sperm is used to form sperm groups, or "trains," which exhib ...200717245446
biomagnification of pbdes in three small terrestrial food chains.eight polybrominated diphenyl ethers (pbde) congeners (iupac nos. 28, 47, 99, 100, 153, 154, 183, and 209) were measured in passerines (great tits--parus major), wood mice (apodemus sylvaticus), and bank voles (clethrionomys glareolus). these data were combined with previously obtained data on pbdes in common buzzards (buteo buteo), sparrowhawks (accipiter nisus), and red fox (vulpes vulpes). this enabled estimation of the biomagnification potential of pbdes in the following three terrestrial fo ...200717310700
the dynamics of murid gammaherpesvirus 4 within wild, sympatric populations of bank voles and wood mice.murid gammaherpesvirus 4 (muhv-4) is widely used as a small animal model for understanding gammaherpesvirus infections in man. however, there have been no epidemiological studies of the virus in wild populations of small mammals. as muhv-4 both infects cells associated with the respiratory and immune systems and attempts to evade immune control via various molecular mechanisms, infection may reduce immunocompetence with potentially serious fitness consequences for individuals. here we report a l ...200717347391
induction and metal speciation of metallothionein in wood mice (apodemus sylvaticus) along a metal pollution gradient.we investigated the binding of cd, cu, and zn to metallothionein (mt) and other metal-binding proteins in free-living wood mice (apodemus sylvaticus l.) captured in four areas along a metal pollution gradient. we measured total and cytosolic cd, cu, and zn concentrations in mouse liver and kidney by means of inductively coupled plasma-mass spectrometry (icp-ms). total (cu, cd, zn)-mt levels were determined in the same tissues by means of the cadmium thiomolybdate saturation assay. metal speciati ...200717373515
molecular detection of bartonella species infecting rodents in slovenia.rodents, collected in three zoogeographical regions across slovenia, were tested for the presence of bartonellae using direct pcr-based amplification of 16s/23s rrna gene intergenic spacer region (its) fragments from splenic dna extracts. bartonella dna was detected in four species of rodents, apodemus flavicollis, apodemus sylvaticus, apodemus agrarius and clethrionomys glareolus, in all three zoogeographic regions at an overall prevalence of 40.4%. the prevalence of infection varied significan ...200717374132
the occurrence of the trematode plagiorchis muris in the wood mouse apodemus sylvaticus in north yorkshire, uk.wood mice apodemus sylvaticus were trapped each september over a 13-year period, from 1993 to 2005, in a wooded area adjacent to malham tarn, yorkshire, uk. plagiorchis muris was found to be the dominant intestinal trematode and occurred in every year of sampling, with an overall prevalence of 16.9%. this appears to be the first record of p. muris in a. sylvaticus within the uk. the mean worm burden was 2.03 and the distribution of the parasite within mice was typically overdispersed. no differe ...200717381868
detection of anaplasma phagocytophilum and ehrlichia sp. hf strains in ixodes ricinus ticks in brittany, france.dna extracts from 156 tick pools, 18 blood specimens and 17 spleens from european woodmice (apodemus sylvaticus) collected in brittany, france were tested by pcr for the 16s rrna gene of anaplasmataceae. positive amplicons were sequenced and confirmed, either by amplification and sequencing of a second gene, or by a second pcr specific for the p44 and glta genes of anaplasma phagocytophilum and the glta gene of ehrlichia sp. hf. in addition to a. phagocytophilum, the study detected ehrlichia sp. ...200717391395
vegetable and animal food sorts found in the gastric content of sardinian wild boar (sus scrofa meridionalis).authors report results emerging from gastric content analysis from n. 96 wild boars hunted in sardinia isle, during the hunting tide (2001-2005), from november to january. mean ph of the gastric content was 3.77 +/- 0.69. mean total capacity (tc) of each stomach was 1702 +/- 680 g. mean stuff ratio (cw/tc) between the content weight (cw) and stomachs tc was 0.45. food categories found in animal stomachs were: 19 categories of vegetal species (allium spp., arbutus unedo, arisarum vulgare, avena f ...200717516948
do wood mice (apodemus sylvaticus l.) use food selection as a means to reduce heavy metal intake?food preference of wood mice from two with heavy metals polluted sites and two unpolluted sites was tested under laboratory and field conditions with two-way choice experiments. in the laboratory, wood mice preferred to eat acorns from unpolluted sites over acorns from polluted sites. previous experience with polluted food had no influence on food choice. preference was negatively related to acorn metal content. furthermore, the nutrient content of the acorn endosperm was consistently lower in p ...200817555856
impairment of endothelium-dependent relaxation of aortas and pulmonary arteries from spontaneously hyperlipidemic mice (apodemus sylvaticus).we evaluated the endothelial function of thoracic aortas and pulmonary arteries in a population of european wood mice (apodemus sylvaticus), which exhibit hypercholesterolemia. according to the plasma cholesterol level, mice were divided into two groups: hypercholesterolemic (ahl, total plasma cholesterol 200-300 mg/dl) and normocholesterolemic (anl, total plasma cholesterol <200 mg/dl). acetylcholine (ach) caused endothelium-dependent relaxation of precontracted aortas and pulmonary arteries. r ...200717616485
ecological differences and coexistence in a guild of microparasites: bartonella in wild rodents.the study of ecological differences among coexisting microparasites has been largely neglected, but it addresses important and unusual issues because there is no clear distinction in such cases between conventional (resource) and apparent competition. here patterns in the population dynamics are examined for four species of bartonella (bacterial parasites) coexisting in two wild rodent hosts, bank voles (clethrionomys glareolus) and wood mice (apodemus sylvaticus). using generalized linear model ...200717645030
evidence of neospora caninum dna in wild rodents.seventy-five house mice (mus musculus), 103 rats (rattus norvegicus) and 55 field mice (apodemus sylvaticus) from north-west italy were pcr analysed for neospora caninum infection. brain, kidney and muscle tissues collected from the above mentioned animals were tested by pcr using np6 and np21 primers. the brain tissue from 2 house mice and 2 rats, the kidney from 4 rats, 1 house mouse and 1 field mouse and muscle from 10 rats, 8 house mice and 1 field mouse were tested positive for n. caninum. ...200717651897
bioaccumulation of metals and effects of a landfill in small mammals. part ii. the wood mouse, apodemus sylvaticus.we assess the bioaccumulation of metals (pb, hg, cd, fe, mg, zn, cu, mn, mo, cr) and effects of landfill leachates on morphological (ri, relative weights), plasma (gpt, got, creatinine), and genotoxic (mnt) parameters in wood mice, apodemus sylvaticus, inhabiting close the garraf landfill site (ne spain). due to the high age- and sex-dependent variation in wild populations, we also studied the effect of these biotic factors on the parameters studied. wood mice from the landfill site, sited in a ...200717681586
tick-borne zoonotic bacteria in wild and domestic small mammals in northern spain.the prevalence and diversity of tick-borne zoonotic bacteria (borrelia spp., anaplasma phagocytophilum, coxiella burnetii, and spotted fever group rickettsiae) infecting 253 small mammals captured in the basque country (spain) were assessed using pcr and reverse line blot hybridization. trapping sites were selected around sheep farms (study 1, 2000 to 2002) and recreational parks (study 2, 2003 to 2005). the majority of the studied mammals (162) were wood mice (apodemus sylvaticus), but six othe ...200717693556
synchrony between fruit maturation and effective dispersers' foraging activity increases seed protection against seed predators.the evolution of pollination and seed dispersal mutualisms is conditioned by the spatial and temporal co-occurrence of animals and plants. in the present study we explore the timing of seed release of a myrmecochorous plant (helleborus foetidus) and ant activity in two populations in southern spain during 2 consecutive years. the results indicate that fruit dehiscence and seed shedding occur mostly in the morning and correspond to the period of maximum foraging activity of the most effective ant ...200717698486
extensive contribution of embryonic stem cells to the development of an evolutionarily divergent host.the full potential of embryonic stem (es) cells to generate precise cell lineages and complex tissues can be best realized when they are differentiated in vivo-i.e. in developing blastocysts. owing to various practical and ethical constraints, however, it is impossible to introduce es cells of certain species into blastocysts of the same species. one solution is to introduce es cells into blastocysts of a different species. however, it is not known whether es cells can contribute extensively to ...200817913699
borrelia burgdorferi sensu lato in siberian chipmunks (tamias sibiricus) introduced in suburban forests in france.numerous vertebrate reservoirs have been described for borrelia burgdorferi sensu lato (sl), which includes the etiological agents of lyme borreliosis (lb). the siberian chipmunk (tamias sibiricus) is a rodent originating from asia, where it is suspected to be a b. burgdorferi reservoir. it has been intentionally released into the wild in europe since the 1970s, but has not yet been subject to any study regarding its association with the lb agent. in this paper we studied siberian chipmunk infes ...200718021026
host specificity and genealogy of the louse polyplax serrata on field mice, apodemus species: a case of parasite duplication or colonisation?the genealogy, population structure and population dynamics of the sucking louse polyplax serrata were analysed across four host species of the genus apodemus. an analysis of 126 sequences of cytochrome c oxidase subunit i using phylogenetic approaches and haplotype networking revealed a clear structure of european samples, forming three distinct and genetically distant clades with different host specificities. although a clear connection was detected between the host and parasite genealogies/ph ...200818021782
rapid sperm acrosome reaction in the absence of acrosomal cd46 expression in promiscuous field mice (apodemus).there is pronounced promiscuity and sperm competition in long-tailed field mice (apodemus sylvaticus). these mice have evolved unusual sperm behaviour favouring rapid fertilisation, including dynamic formation of sperm trains and their subsequent dissociation. the cell surface complement regulatory (creg) protein cd46 is broadly expressed in eutherian mammals other than rodents, in which it is expressed solely on the spermatozoal acrosomal membrane. ablation of the cd46 gene has been associated ...200718042631
echinococcus multilocularis in belgium: prevalence in red foxes (vulpes vulpes) and in different species of potential intermediate hosts.echinococcus multilocularis causes a rare but potentially lethal zoonotic infection in humans. this tapeworm is known to be endemic in foxes in several countries of western and central europe. in western europe, the common vole (microtus arvalis) and the water vole (arvicola terrestris) are considered to be the most important intermediate host species of this cestode whereas the red fox is by far the most important final host. the purpose of this study was to provide data on the prevalences in w ...200818164551
eye morphology in some wild rodents.the eye anatomy of six rodent species (murinae: apodemus sylvaticus, mus domesticus, and mus spretus; arvicolinae: clethrionomys glareolus, arvicola terrestris and microtus arvalis) was compared by means of light or electron microscopy to determine adaptive, and evolutive signals. our observations revealed inter-specific morphological differences, which were moderate among representatives of the same subfamily. specifically, traits that distinguished murines from arvicolines were the globe's rel ...200818197899
apodemus sylvaticus (loxt) is a suitable mouse strain for testing spatial memory retention in the morris water maze.information on the difference in cognitive function between laboratory and wild-caught mice is anecdotal and this question has not been systematically studied. moreover, studying a wild-caught mouse strain per se may add information to the repertoire of mouse strains available. we aimed to study spatial memory in a wild mouse strain (apodemus sylvaticus, as) as compared to two individual laboratory mouse strains. male as (n=20), cd1 (n=19) and c57bl/6j mice (n=19), 12-14 weeks old, were used in ...200818242105
the relationships between ixodes ricinus and small mammal species at the woodland-pasture interface.ixodes ricinus, as vector, and small mammals, as reservoirs, are implicated in pathogen transmission between wild fauna, domestic animals and humans at the woodland-pasture interface. the ecological relationship between ticks and small mammals was monitored in 2005 on four bocage (enclosed pastureland) sites in central france, where questing ticks were collected by dragging and small mammals were trapped. questing i. ricinus tick and small mammal locations in the environment were assessed throug ...200818247140
evaluation of some sources of variability in using small mammals as pollution biomonitors.in the present study the effects of gender, age and nutritional status on tissue concentrations of some trace elements (zn, cu, mn, and cr) in wood mouse (apodemus sylvaticus), spanish shrew (sorex granarius), and great white-toothed shrew (crocidura russula) were investigated. four sampling stations were selected for the study: a restored mine dump, an area characterised by ultrabasic soil and two sites in oak woods in the vicinity of a power plant. gender had no effect on the tissue concentrat ...200818313721
heavy metal transfers between trophic compartments in different ecosystems in galicia (northwest spain): essential elements.in the present study, we determined the concentrations of cu, fe, mn, and zn in soil and several trophic compartments at a total of 16 sampling stations. the trophic compartments studied were primary producers, represented by two species of terrestrial mosses (pseudoescleropodium purum and hypnum cupressiforme) and oak trees (quercus robur or q. pyrenaica); primary consumers, represented by the wood mouse (apodemus sylvaticus) and the yellow necked mouse (a. flavicollis); secondary consumers, re ...200818350242
population, environmental, and community effects on local bank vole (myodes glareolus) puumala virus infection in an area with low human incidence.in this study, the distribution of puumala hantavirus (puuv) infection in local bank vole myodes glareolus populations in an area with low human puuv infection (nephropathia epidemica [ne]) incidence in northern belgium was monitored for 2 consecutive years. bank voles were trapped in preferred habitat and tested for anti-puuv igg. infection data were related to individual bank vole features, population demography, and environmental variables. rare occurrence of puuv infection was found and puuv ...200818370592
[fleas community in introduced siberian chipmunks (tamias sibiricus laxmann) in forest of sénart, france].we examined the fleas community in an introduced population of siberian chipmunks, tamias sibiricus, between 2005 and 2007, in the forest of sénart (essonne, france). we collected and identified 383 fleas on 463 chipmunks (total: 1,891 captures on 471 chipmunks). in 2005, 120 fleas were also collected on 65 bank voles, clethrionomys glareolus, and on 25 wood mice, apodemus sylvaticus, trapped within the same area. ceratophyllus sciurorum sciurorum formed 73.6% of the chipmunks' flea community, w ...200818416245
the influence of climatic conditions on long-term changes in the helminth fauna of terrestrial molluscs and the implications for parasite transmission in southern england.the influence of climatic conditions on the prevalence and transmission of helminth parasites in a terrestrial mollusc population was studied in a grassland site in southern england between 1974 and 1983. molluscs were sampled in each september of 5 years over this period (1974, 1976, 1979, 1981, 1983). climatic conditions had a variable effect on parasite prevalence. trematode sporocyst infections increased after wet summer and warm winter conditions and declined in hot, dry periods. cestode in ...200818598579
the role of rodents and shrews in the transmission of toxoplasma gondii to pigs.inadequate rodent control is considered to play a role in toxoplasma gondii infection of pigs. this issue was addressed in the current study by combining a 4-month rodent control campaign and a 7-month longitudinal analysis of t. gondii seroprevalence in slaughter pigs. three organic pig farms with known rodent infestation were included in the study. on these farms, presence of t. gondii in trapped rodents was evaluated by real-time pcr. all rodent species and shrews investigated had t. gondii d ...200818606498
presence of pathogenic borrelia burgdorferi sensu lato in ticks and rodents in zhejiang, south-east china.a molecular epidemiological survey was conducted to investigate the presence of pathogenic borrelia burgdorferi sensu lato (s.l.) species in the forest areas of zhejiang province, south-east china. a total of 182 ticks of 6 species and 200 rodents of 8 species were collected and individually examined for the presence of b. burgdorferi s.l. dna by nested pcr targeting the 5s-23s rrna intergenic spacer. forty-one ticks of four species, haemaphysalis concinna, haemaphysalis longicornis, rhipicephal ...200818628499
detection of antibodies against anaplasma phagocytophilum in algerian mice (mus spretus), portugal.the recent detection of anaplasma phagocytophilum in portugal stimulated further research on the agent's enzootic cycle, which usually involves rodents. thus a total 322 rodents belonging to five species, including 30 apodemus sylvaticus (wood mouse), 65 mus musculus (house mouse), 194 m. spretus (algerian mouse), 5 rattus norvegicus (brown rat) and 28 r. rattus (black rat), were studied by indirect immunofluorescent assay (ifa) and/or polymerase chain reaction (pcr) for a. phagocytophilum expos ...200918973448
comparison of two pcr protocols for the detection of neospora caninum dna in rodents.the objective of the present study was, due to increasing interest in the epidemiological role of small mammals as potential reservoir of neospora caninum, to compare two different pcr protocols for the diagnosis of n. caninum in rodents. we tested tissue samples from 50 house mice (mus musculus), 50 rats (rattus norvegicus) and 35 field mice (apodemus sylvaticus). two different pcr protocols based on primer pairs, np4-np7 and np6plus-np21plus, were used for diagnosis on these samples. while the ...200919036521
why do siberian chipmunks tamias sibiricus (sciuridae) introduced in french forests acquired so few intestinal helminth species from native sympatric murids?a lack of newly acquired species partly explains why introduced host species have poor specific parasite diversity. the intestinal helminth community from two native murid host species, wood mice apodemus sylvaticus [murinae] (n=40), bank voles clethrionomys glareolus [arvicolinae] (n=42), and an introduced sciurid, the siberian chipmunk tamias sibiricus (n=42), dominant in the rodent communities, was studied from three woody areas in the ile-de-france region. native gastrointestinal helminth fa ...200919050922
[morpho-functional characteristics of reproductive organs of rodents from the area affected by a plant, processing gas with the increased content of sulfur compounds].the biology of reproduction of 5 rodent species--small gopher (spermophilus pygmaeus pallas, 1778), reddish gopher (spermophilus major pallas, 1779), sasin lemmer (lagurus lagurus pallas,1773), forest mouse (apodemus sylvaticus linnaeus) and bank vole(clethrionomys glareolus schreber, 1780)--inhabiting the sanitary protective zone of the gas processing plant, was investigated with the use of histological, electron microscopical, immunocytochemical and morphometric methods. intensification of the ...200819102254
association between habitat and prevalence of hantavirus infections in bank voles (myodes glareolus) and wood mice (apodemus sylvaticus).in order to determine the habitat preferred by myodes (before clethrionomys) glareolus and the corresponding puumala hantavirus seroprevalence in those habitats, we captured rodents simultaneously in three significantly different habitats. we compared trapping success and presence of virus per habitat during an ongoing epidemic in order to test the hypothesis of a density-dependent seroprevalence. our study showed that bank vole population density, as well as puumala virus seroprevalence, were h ...200919271997
immunomodulatory parasites and toll-like receptor-mediated tumour necrosis factor alpha responsiveness in wild mammals.immunological analyses of wild populations can increase our understanding of how vertebrate immune systems respond to 'natural' levels of exposure to diverse infections. a major recent advance in immunology has been the recognition of the central role of phylogenetically conserved toll-like receptors in triggering innate immunity and the subsequent recruitment of adaptive response programmes. we studied the cross-sectional associations between individual levels of systemic toll-like receptor-med ...200919386086
encephalomyocarditis virus infection in wildlife species in greece.the objective of this work was to search for potential wildlife reservoir hosts of encephalomyocarditis virus (emcv) in wildlife species. from 1994 to 2006, 317 blood and tissue samples were collected from 17 wildlife species in greece. encephalomyocarditis virus was isolated only from two rattus rattus. in addition, antibody to emcv were detected in sera from 39 rattus rattus, one apodemus sylvaticus, one microtus arvalis, and 13 sus scrofa.200919395765
no effect of running and laboratory housing on adult hippocampal neurogenesis in wild caught long-tailed wood mouse.studies of adult hippocampal neurogenesis (ahn) in laboratory rodents have raised hopes for therapeutic interventions in neurodegenerative diseases and mood disorders, as ahn can be modulated by physical exercise, stress and environmental changes in these animals. since it is not known whether cell proliferation and neurogenesis in wild living mice can be experimentally changed, this study investigates the responsiveness of ahn to voluntary running and to environmental change in wild caught long ...200919419549
helminth species richness in wild wood mice, apodemus sylvaticus, is enhanced by the presence of the intestinal nematode heligmosomoides polygyrus.we analysed 3 independently collected datasets of fully censused helminth burdens in wood mice, apodemus sylvaticus, testing the a priori hypothesis of behnke et al. (2005) that the presence of the intestinal nematode heligmosomoides polygyrus predisposes wood mice to carrying other species of helminths. in portugal, mice carrying h. polygyrus showed a higher prevalence of other helminths but the magnitude of the effect was seasonal. in egham, mice with h. polygyrus showed a higher prevalence of ...200919486546
patterns of orthopox virus wild rodent hosts in south germany.although cowpox virus (cpxv) infections in a variety of dead-end hosts have been investigated in germany for more than 50 years, data on species and geographical distribution of cpxv in reservoir hosts are sparse. here we present the first comprehensive study of 825 rodents that have been collected in bavaria, southern germany. in summary, six different rodent species (apodemus flavicollis, myodes glareolus, microtus arvalis, apodemus sylvaticus, microtus agrestis, and arvicola amphibius) were t ...200919492947
cd55 and cd59 protein expression by apodemus (field mice) sperm in the absence of cd46.the mammalian female reproductive tract has an abundance of complement components, which play a vital role in protection against genital pathogens. sperm may be protected against complement-mediated damage by complement regulatory proteins, including membrane cofactor protein (cd46), decay accelerating factor (cd55) and cd59. however, sperm from apodemus (field mice) do not express cd46 protein. the aim of the present study was to determine whether apodemus sperm may be protected against complem ...200919501411
small-scale indirect effects determine the outcome of a tripartite plant-disperser-granivore interaction.the microhabitat in which plants grow affects the outcome of their interactions with animals, particularly non-specialist consumers. nevertheless, as most research on this topic has dealt with either mutualists or antagonists, little is known about the indirect effects of plant microhabitats on the outcome of tripartite interactions involving plants and both mutualists (e.g. seed dispersers) and antagonists (e.g. granivores). during three consecutive years, we analysed small-scale variations in ...200919579034
the helminth community of the wood mouse apodemus sylvaticus in a mediterranean ecosystem in regeneration ten years after a wildfire.this study was carried out 10 years after a wildfire in the spanish serra calderona natural park, following a previous analysis comprising the first 5 years after the fire. its primary aim was to elucidate the impact of this perturbation on the population biology of the wood mouse apodemus sylvaticus, and the repercussions on its helminth community in this regenerating mediterranean ecosystem. second, confirmation of the ability of the parasites to tolerate environmental stressors and the effect ...201019580689
detection of bartonella spp. in wild rodents in israel using hrm real-time pcr.the prevalence of bartonella spp. in wild rodents was studied in 19 geographical locations in israel. one hundred and twelve rodents belonging to five species (mus musculus, rattus rattus, microtus socialis, acomys cahirinus and apodemus sylvaticus) were included in the survey. in addition, 156 ectoparasites were collected from the rodents. spleen sample from each rodent and the ectoparasites were examined for the presence of bartonella dna using high resolution melt (hrm) real-time pcr. the met ...200919595521
effects of soil properties on food web accumulation of heavy metals to the wood mouse (apodemus sylvaticus).effects of soil properties on the accumulation of metals to wood mice (apodemus sylvaticus) were evaluated at two sites with different ph and organic matter content of the soil. ph and organic matter content significantly affected accumulation of cd, cu, pb and zn in earthworms and vegetation. for cd, cu and zn these effects propagated through the food web to the wood mouse. soil-to-kidney ratios differed between sites: cd: 0.15 versus 3.52, cu: 0.37 versus 1.30 and zn: 0.33-0.83. this was confi ...201019647912
molecular characterization of a new isolate of borrelia lusitaniae derived from apodemus sylvaticus in portugal.a total of 196 small mammals were collected in portugal and tested for borrelia burgdorferi sensu lato. tissue samples were taken from each animal and cultured in barbour-stoenner-kelly (bsk)-ii medium. the single strain of spirochete isolated was confirmed as borrelia lusitaniae by genetic analyses. this is the first report of b. lusitaniae isolated from apodemus sylvaticus.201019725761
developmental constraints revealed by co-variation within and among molar rows in two murine rodents.morphological integration corresponds to interdependency between characters that can arise from several causes. proximal causes of integration include that different phenotypic features may share common genetic sets and/or interact during their development. ultimate causes may be the prolonged effect of selection favoring integration of functionally interacting characters, achieved by the molding of these proximal causes. strong and direct interactions among successive teeth of a molar row are p ...200919754715
bioaccumulation of metals and effects of a landfill in small mammals part iii: structural alterations.the leachates from the garraf landfill located in a protected site (ne spain) contain several potentially toxic substances such as heavy metals. here we report the histopathological alterations produced by this pollution in wild specimens of an omnivorous species, the wood mouse, apodemus sylvaticus, and an insectivorous species, the greater white-toothed shrew, crocidura russula. hepatic tissue presented the most severe alterations in both the species, namely cell cycle arrest (apoptosis and ne ...200919758588
independent lineage of lymphocytic choriomeningitis virus in wood mice (apodemus sylvaticus), spain.to clarify the presence of lymphocytic choriomeningitis virus (lcmv) in spain, we examined blood and tissue specimens from 866 small mammals. lcmv rna was detected in 3 of 694 wood mice (apodemus sylvaticus). phylogenetic analyses suggest that the strains constitute a new evolutionary lineage. lcmv antibodies were detected in 4 of 10 rodent species tested.200919861074
involvement of individual hippocampal signaling protein levels in spatial memory formation is strain-dependent.although a series of signaling cascades involved in spatial memory have been identified, their link to spatial memory and strain-dependent expression has not been reported so far. hippocampal levels of the abovementioned signaling proteins were determined in laboratory inbred strain c57bl/6j, the wild-derived inbred strain pwd/phj and the wild caught mouse apodemus sylvaticus (as) by immunoblotting. the resulting hippocampal protein levels were correlated with results from mwm. hippocampal signa ...201019890699
characterization of a novel wood mouse virus related to murid herpesvirus 4.two novel gammaherpesviruses were isolated, one from a field vole (microtus agrestis) and the other from wood mice (apodemus sylvaticus). the genome of the latter, designated wood mouse herpesvirus (wmhv), was completely sequenced. wmhv had the same genome structure and predicted gene content as murid herpesvirus 4 (muhv4; murine gammaherpesvirus 68). overall nucleotide sequence identity between wmhv and muhv4 was 85 % and most of the 10 kb region at the left end of the unique region was particu ...201019940063
linkage of hippocampal proteins to spatial memory formation and strain-dependence in apodemus sylvaticus, c57bl/6j and pwd/phj mice.strain-dependence of performance in the morris water maze (mwm) has been reported but information on underlying differences at the protein level as well as linkage of hippocampal proteins to memory is limited. no data are available on differences in hippocampal protein levels between (within-strain) "good" and "bad" performers in the mwm. hippocampi of wild-caught mouse strain apodemus sylvaticus (as), laboratory inbred mouse strain c57bl/6j and wild-derived inbred mouse strain pwd/phj, that wer ...201020036702
pathogenesis of a model gammaherpesvirus in a natural host.murine gammaherpesvirus 68 (mhv-68) infection of laboratory mice (mus musculus) is an established model of gammaherpesvirus pathogenesis. the fact that m. musculus is not a host in the wild prompted us to reassess mhv-68 infection in wood mice (apodemus sylvaticus), a natural host. here, we report significant differences in mhv-68 infection in the two species: (i) following intranasal inoculation, mhv-68 replicated in the lungs of wood mice to levels approximately 3 log units lower than in balb/ ...201020130062
heavy metal content in the femora of yellow-necked mouse (apodemus flavicollis) and wood mouse (apodemus sylvaticus) from different types of polluted environment in slovakia.heavy metal content in the femora of yellow-necked mouse (apodemus flavicollis) and wood mouse (apodemus sylvaticus) caught in different polluted biotopes of a low hill level in slovakia (nováky and kolínany) was investigated in the present study. length, weight and histological structure of mouse bones have also been analysed. according to our results, higher concentrations of cd, ni, fe, cu and zn were detected in the femora of a. flavicollis from kolínany area. similarly, we observed higher c ...201020135219
interactions between anomalous excretory and tegumental epithelia in aberrant mesocestoides tetrathyridia from apodemus sylvaticus in spain.tetrathyridia of mesocestoides sp. (platyhelminthes: cestoda) were collected from the body cavities of apodemus sylvaticus (rodentia: muridae) in murcia, spain, and processed by routine microscopical and histological techniques, including examination with brightfield, phase-contrast, and differential-interference-contrast optics. all specimens examined had solid hindbodies (i.e., lacked a primary lacuna), thus conforming to the plerocercoid metacestode type. the vast majority of tetrathyridia we ...201020165874
detecting interactions between parasites in cross-sectional studies of wild rodent populations.there is extensive and convincing evidence from experimental studies that interactions exist between helminths of different species during concurrent infections in laboratory rodents. among the strongest interactions are those that arise from immune responses of the hosts. however, detecting comparable relationships in data acquired from wild rodent populations has not been easy. in general, helminth infections in naturally occurring rodent populations show highly predictable trends; seasonal, h ...200920209801
some effects on the urogenital sinus of mulot embryos (apodemus sylvaticus l) from the injection of androgen hormone and estrogen hormone into the pregnant mother, during the last days of gestation. 194720247836
presence of prostatic buds in female mulot (apodemus sylvaticus l.) fetuses from mothers who were ovariectomized during gestation and who received progesterone injections. 194720248862
tula virus in populations of small terrestrial mammals in a rural landscape.over 5 years (2000-2004), populations of small mammals from a rural landscape in southern moravia (czech republic) were investigated for the presence of tula virus (tulv) antigen using the elisa set hantagnost. in total, 1566 individuals from 10 species were examined. the prevalence in the common vole (microtus arvalis pallas 1778), the main reservoir of tulv, was 10% (n = 871). the prevalence of tulv antigen increases with its population numbers. the highest number of tulv antigen-positive comm ...201020420534
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