Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| antibodies to rickettsia rickettsii in peromyscus leucopus from a focus of rocky mountain spotted fever in connecticut. | during 1980-1982, white-footed mice (peromyscus leucopus) were captured in newtown, connecticut, an area where rickettsia rickettsii, the etiologic agent of rocky mountain spotted fever, is thought to be enzootic. an indirect microimmunofluorescence test identified specific antibodies to this organism in 16 of 237 (7%) sera: titration end points for 14 samples were relatively high (1:128-1:2048). antibodies were detected in mice during 1980 and 1981 with monthly prevalences varying from 8 to 22% ... | 1984 | 6744122 |
| transmission studies with sarcocystis idahoensis of deer mice (peromyscus maniculatus) and gopher snakes (pituophis melanoleucus). | transmission studies with sarcocystis idahoensis of deer mice (peromyscus maniculatus) and gopher snakes (pituophis melanoleucus) were conducted to determine host specificity of various stages of the parasite. sporocysts were not passed by four dogs or four cats fed infected skeletal muscle from deer mice. seven white mice (mus musculus) and 34 white-footed mice (peromyscus leucopus) were negative for sarcocysts and liver meronts following oral inoculation with s. idahoensis sporocysts; however, ... | 1980 | 6776292 |
| endemicity of spotted fever group rickettsiae in connecticut. | to compare rickettsial infectivity and seropositivity rates against spotted fever group (sfg) rickettsiae, ticks and wild mammals were collected from three areas where rickettsia rickettsii was thought to be enzootic in connecticut during 1978-1979, and from four additional sites (with no reported human cases) between 1976 and 1979. of the 1,001 dermacentor variabilis examined by the hemolymph test, 59 (5.9%) contained rickettsia-like organisms; direct immunofluorescence tests verified the prese ... | 1981 | 6789690 |
| effects of intermittent 60-hz high voltage electric fields on metabolism, activity, and temperature in mice. | transient effects of 100-kv/m extremely low frequency electric fields were studied in the white footed deermouse, peromyscus leucopus. gross motor activity, carbon dioxide production, oxygen consumption, and core body temperature were monitored before, during, and after intermittent field exposures (four hour-long exposures, at one-hour intervals). thirty-four mice were exposed in cages with plastic floors floating above ground potential, and 21 mice were exposed in cages with grounded metal flo ... | 1981 | 6798977 |
| on the occurrence of a myeloid body in pinealocytes of the white-footed mouse, peromyscus leucopus. an electron-microscopic study. | the fine-structural features of pinealocytes of the white-footed mouse, peromyscus leucopus, were examined. a single population of pinealocytes was observed in both superficial and deep components of the gland. cells in both locations are characterized by the presence of an indented nucleus exhibiting a prominent nucleolus. the usual organelles in the perikaryon are the golgi complexes, mitochondria, endoplasmic reticulum, polysomes, microtubules and dense-core vesicles. in addition the perikary ... | 1983 | 6831535 |
| inverse correlation between "synaptic" ribbon number and the density of adrenergic nerve endings in the pineal gland of various mammals. | the number of "synaptic" ribbons was inversely correlated with the density of the adrenergic nerve endings of the pineal gland compared among a diverse group of species including the fox, cat, rat, cotton rat, white-footed mouse, djungarian hamster, ground squirrel, and chipmunk. the concentration of norepinephrine paralleled the number of adrenergic nerve terminals in the pineal glands of the cotton rat, rat, and ground squirrel, the only species in which norepinephrine concentrations were meas ... | 1983 | 6837939 |
| a possible mechanism of rapid luteolysis in white-footed mice, peromyscus leucopus. | adult female white-footed mice, peromyscus leucopus, were exposed to long (lp) or short (sp) photoperiods for 6 weeks (experiment i). another group of animals was kept for 6 weeks in sp, then injected sc with 30 micrograms prolactin twice daily for 2, 3, 4, or 6 days (experiment ii). ovaries from the mice in both experiments were weighed and serially sectioned for light microscopic examination of regressing corpora lutea. in experiment i, it was observed that vessels supporting corpora lutea wer ... | 1983 | 6864810 |
| spirochetes in ixodes dammini and mammals from connecticut. | spirochetes were observed in the midguts of 35% of 147 motile ixodes dammini from three locations in lyme and east haddam, connecticut. positive ticks were removed from eastern chipmunks (tamias striatus), raccoons (procyon lotor), white-footed mice (peromyscus leucopus), and a red squirrel (tamiasciurus hudsonicus). spirochetes were isolated in fortified kelly's medium from nine questing or partially engorged i. dammini adults and nymphs and from the bloods of a raccoon and a white-footed mouse ... | 1983 | 6881431 |
| diurnal rhythm of response to chronic intrahypothalamic melatonin injections in the white-footed mouse, peromyscus leucopus. | a pronounced diurnal change in responsiveness to intrahypothalamic melatonin injections was observed in the white-footed mouse, peromyscus leucopus. 7 weeks of chronic daily afternoon (12 h after lights-on) injections of 500 ng melatonin into the vicinity of the suprachiasmatic nuclei (scn) caused a 66% reduction in female reproductive tract weight relative to saline-injected controls (p less than 0.01), with 83% of these animals having an imperforate vagina, and no animals having mature follicl ... | 1982 | 6890151 |
| effects of advancing age on hypothalamic-hypophysial-testicular functions in the male white-footed mouse (peromyscus leucopus). | 1980 | 6994828 | |
| effects of advancing age on the hypothalamic-pituitary-ovarian axis of the female white-footed mouse (peromyscus leucopus). | peromyscus leucopus, with an average lifespan of 48 months, showed unchanged levels of serum luteinizing hormone (lh), estradiol, progesterone, and pituitary lh and prolactin, between the ages of 12 and 48 months. hypothalamic lh-releasing hormone (lhrh), norepinephrine and dopamine also remained unchanged with advancing age. ovarian and uterine weight decreased with age, although the changes in uterine weight were not statistically significant. these data indicate that the hypothalamic-pituitar ... | 1980 | 7000517 |
| native trichinosis in wild rodents in henrico county, virginia. | encapsulated larvae of trichinella spiralis were found in wild-trapped, microtus pennsylvanicus and sigmodon hispidus. in addition, peromyscus leucopus and mus musculus again were found infected. these mammals were trapped from a farm site in henrico county, virginia, remote from known potential sources of trichinosis. the possible zoonotic relationship between wild rodent trichinosis and swine trichinosis is discussed. | 1980 | 7001047 |
| reservoir hosts of human babesiosis on nantucket island. | the host range of babesia microti was studied on nantucket island in order to identify the enzootic reservoir of this human pathogen. white-footed mice (peromyscus leucopus) were more frequently parasitized than were other indigenous animals. infection was ubiquitous in locations where deer were abundant. mice were most frequently parasitemic during spring and summer and adults more frequently than juveniles. parasitemia, which was rarely intense, was sustained for as long as 4 months. mice live ... | 1981 | 7020449 |
| evidence for a brain site of melatonin action in the white-footed mouse, peromyscus leucopus. | a brain site of melatonin action has been determined for the white-footed mouse (peromyscus leucopus). melatonin-beeswax implants releasing small quantities of melatonin (less than 100 ng/day) caused a 50% reduction in reproductive tract weight relative to controls (p less than 0.025) with 83% of these animals having an imperforate vagina, when implanted in the anterior hypothalamic nuclei (ah) and suprachiasmatic nuclei (scn). subcutaneous implants had little effect. implants in the ah and scn ... | 1982 | 7057959 |
| daily melatonin rhythms in photoperiod sensitive and insensitive white-footed mice (peromyscus leucopus). | 1982 | 7111341 | |
| geographic variation in peromyscus leucopus: short-day induced reproductive regression and spontaneous recrudescence. | in order to determine if intraspecific differences exist in the photoperiodic control of the reproductive cycle of white-footed mice (peromyscus leucopus), 34 male and 60 female mice from either connecticut (ct), virginia (va), or georgia (ga) laboratory stocks were exposed to either a long (16l:8d) or short (9l:15d) photoperiod for up to 27 weeks. reproductive status (testis length or the presence of a perforate vagina) of these mice was assessed every 1 to 2 weeks. after this time, the males w ... | 1982 | 7126737 |
| preantral intra-ovarian oocyte release in the white-footed mouse, peromyscus leucopus. | adult white-footed mice, peromyscus leucopus, were kept either in long photoperiod (lp; ld 16:8) or in short photoperiod (sp; ld 8:16) for six weeks. ovaries were serially sectioned and examined histologically. preantral follicles were observed to release their oocyte into the ovarian stroma. this phenomenon is termed "preantral intra-ovarian oocyte release (pior)". the first step in pior appeared to be the interruption of the basal membrane and the thecal layer. pior was considered incomplete w ... | 1982 | 7127440 |
| intraspecific differences for melatonin-induced reproductive regression and the seasonal molt in peromyscus leucopus. | 1982 | 7152235 | |
| effects of advancing age on the ultrastructure of pinealocytes in the male white-footed mouse (peromyscus leucopus). | quantitative comparison of pinealocyte ultrastructure in 3-month-old and 28-month-old male white-footed mice (peromyscus leucopus) revealed decreases both in the area of the golgi apparatus and in the number of dense-core vesicles. in contrast, no differences between these two age groups were noted in the areas of granular endoplasmic reticulum, vacuoles with flocculent content, lysosome-like bodies, or mitochondria. nor were any changes between groups of mice apparent in pinealocyte nuclear or ... | 1982 | 7153722 |
| evidence for turnover of dna in the nucleus and in the cytoplasm of adult post-mitotic neurons in vivo. | experiments were designed to determine if turnover of dna occurs in post-mitotic neurons of adult mammals. three-month-old laboratory mice, mus musculus, and white footed mice, peromyscus leucopus, were given three injections of 3h-thymidine (3h-tdr, 16 muci/g body weight) at noon, 4 pm and 8 pm, and were killed serially beginning 1 h after the last injection. the brain stem was removed from the animals and autoradiographed. some of the sections were treated with dnase prior to autoradiography. ... | 1982 | 7160228 |
| daily melatonin injections: their usefulness in understanding photoperiodism in peromyscus leucopus. | 1982 | 7166440 | |
| aging and ovarian function in the white-footed mouse (peromyscus leucopus) with specific reference to the development of preovulatory follicles. | a study was made of the effects of increasing age on uterine histology, follicular development and steroidogenesis within the ovary of the white-footed mouse (peromyscus leucopus). the animals were autopsied on each day of the estrous cycle and ranged from 14 to 49 mos. of age. the data indicated that the animals maintained estrous cycles throughout their lifespan as judged by cyclic changes in uterine histology. in addition these studies showed that aging (1) did not alter ovarian concentration ... | 1980 | 7191810 |
| aggressive behavior during the reproductive cycle of female peromyscus leucopus: effects of encounter site. | 1980 | 7192547 | |
| antigonadal effects of melatonin in white-footed mice (peromyscus leucopus). | 1980 | 7193487 | |
| brief report prolactin-induced aggression in female peromyscus leucopus. | 1981 | 7197915 | |
| effect of long or short photoperiod on pineal melatonin content in the white-footed mouse, peromyscus leucopus. | 1981 | 7198175 | |
| intraperitoneal transmitters in suckling white-footed mice, peromyscus leucopus. | intraperitoneal transmitter implantation in suckling white-footed mice, peromyscus leucopus, was studied. postnatal morphological development varied. age ranged from 9 to 16 days, and body weight ranged from 4.4 to 7.3 g. interference by mothers prevented successful implantation on sucklings which retained their neonatal appearance. growth was measured in 6 sucklings for 21 days. observed growth rates based on daily weight gain per 24 h were 0.29 and 0.32 g for implanted and control mice, respec ... | 1980 | 7213956 |
| on the activity and fidelity of chromatin-associated hepatic dna polymerase-beta in aging murine species of different life spans. | activity and accuracy of chromatin-directed dna replication have been compared in young and aged mus musculus and peromyscus leucopus, two murine species with contrasting maximum lifespans. chromatin isolated from livers of mature adults of both species copied efficiently exogenous dna templates using predominantly dna polymerase-beta. the dna synthetic activity of liver chromatin remained constant in both species throughout their lifetimes. the fidelity of chromatin-directed poly [d(a-t)] synth ... | 1981 | 7217221 |
| effects of daily melatonin injections on female reproduction in the white-footed mouse, peromyscus leucopus. | 1981 | 7262537 | |
| migratory kinetics of cuterebra fontinella (diptera: cuterebridae) in the white-footed mouse, peromyscus leucopus. | larvae of the rodent botfly, cuterebra fontinella, follow a consistent migration route thorough their natural host, the white-footed mouse, peromyscus leucopus. larvae that enter the eye or nares spend about 48 hr in the nasal cavity and then follow a caudally oriented path that leads through the nasal passage, trachea, thoracic and abdominal cavities, and ends in the subcutaneous tissues of the posteroventral abdominal region. larvae that enter mice through the anus or by injection into the sub ... | 1981 | 7264830 |
| photoperiodic regulation of reproduction in postpartum peromyscus leucopus. | 1981 | 7272403 | |
| effects of 18 weeks of daily melatonin injection on reproduction and temperature regulation in the mouse, peromyscus leucopus. | mice injected daily with 50 microgram of melatonin, 12 hr after lights on, for 18 weeks, underwent gonadal regression after 4-7 weeks and reproductive recrudescence after 15 weeks. most treated animals molted to the winter pelt after 9-11 weeks of injections, and 2 of the 10 mice experienced bouts of daily torpor after 14 weeks. | 1981 | 7288388 |
| melatonin: identification of sites of antigonadal action in mouse brain. | long-term implants releasing a small quantity of melatonin (45 nanograms per day) were used to determine the brain sites of the hormone's antigonadal action in a photoperiodic species, the white-footed mouse (peromyscus leucopus). implants in the medial preoptic and supra- and retrochiasmatic areas elicited completed gonadal regression after 7 weeks. implants in other brain regions had little effect on the animals' reproductive state. | 1981 | 7292016 |
| capillary supply of skeletal muscles from acclimatized white-footed mice peromyscus. | winter-acclimatized white-footed mice (peromyscus leucopus) can increase their aerobic heat production under cold stress by 70%. the possibility that changes in microvascular supply might account, in part, for some of this increased thermogenic capacity was examined in one of the primary thermogenic tissues, skeletal muscle. capillaries were stained histochemically in four hindlimb muscles of freshly captured peromyscus in summer and winter. capillary density, mean fiber area, and mean capillari ... | 1981 | 7304781 |
| effect of geographical origin on the photoperiodic control of reproduction in the white-footed mouse, peromyscus leucopus. | 1981 | 7306637 | |
| mucus-secreting glands and goblet cells in the trachea of the deer mouse, peromyscus leucopus. | 1981 | 7324325 | |
| temperature regulation in the mouse, peromyscus leucopus: effects of various photoperiods, pinealectomy and melatonin administration. | 1980 | 7364518 | |
| methods for detecting babesia microti infection in wild rodents. | we compared various methods for detecting babesia microti infection in white-footed mice (peromyscus leucopus) captured in enzootic regions of massachusetts. the most sensitive method tested involved inoculating blood from wild rodents into hamsters. one month postinoculation proved to be the optimal time for microscopically examining blood of inoculated hamsters. with this method, as few as 300 organisms produced patent infection. prior splenectomy of hamsters did not increase susceptibility to ... | 1980 | 7365625 |
| photoperiodic regulation of reproductive development in white-footed mice (peromyscus leucopus). | 1980 | 7397311 | |
| effects of temperature, photoperiod, and daily torpor on thyroid function in the white-footed mouse, peromyscus leucopus. | 1980 | 7409461 | |
| inheritance and expression of esterase-1 allozymes in peromyscus leucopus. | we analyzed inheritance of 5 es-1 alleles in p leucopus and found them to be co-dominant and segregating from a single autosomal locus, thereby verifying assumptions of mendelian inheritance implicit in field data. we also described an allele that is 'silent' in hemolysate, but is active in liver extract. | 1980 | 7418791 |
| effect of photoperiod and melatonin on testicular development in the white-footed mouse, peromyscus leucopus. | at autopsy the absolute and relative testicular weights of 6-week-old white-footed mice were significantly lower (p < 0.001) in animals exposed to a short photoperiod (8l : 16d) or exposed to a long photoperiod (16l : 8d) and treated with a 1 mg melatonin s.c. implant than in those kept only in a long photoperiod. the long photoperiod animals had tests of normal appearance and complete spermatogenesis, but there had been little development in the testes of the other animals and seminiferous tubu ... | 1980 | 7431321 |
| photoperiodic regulation of the testes of adult white-footed mice (peromyscus leucopus). | 1980 | 7448286 | |
| molecular linkage of hantavirus pulmonary syndrome to the white-footed mouse, peromyscus leucopus: genetic characterization of the m genome of new york virus. | the complete m segment sequences of hantaviruses amplified from tissues of a patient with hantavirus pulmonary syndrome in the northeastern united states and from white-footed mice, peromyscus leucopus, from new york were 99% identical and differed from those of four corners virus by 23%. the serum of this patient failed to recognize a conserved, immunodominant epitope of the four corners virus g1 glycoprotein. collectively, these findings indicate that p. leucopus harbors a genetically and anti ... | 1995 | 7494337 |
| antibody response of the mouse reservoir of borrelia burgdorferi in nature. | to determine whether the white-footed mouse reservoir host (peromyscus leucopus) of the agent of lyme disease (borrelia burgdorferi) naturally mounts an immune response against the full range of antigens expressed by this zoonotic pathogen, we analyzed the pattern of immunoreactivity of these rodents at sites in which the intensity of transmission differs. although the incidence of seroconversion within the reservoir population relates proportionally to the density of subadult deer ticks (ixodes ... | 1995 | 7622226 |
| analysis of borrelia burgdorferi sequentially isolated from peromyscus leucopus captured at a lyme disease enzootic site. | thirty isolates of borrelia burgdorferi sequentially cultured from 15 naturally infected white-footed mice (peromyscus leucopus) were examined for variability in protein and plasmid profiles. heterogeneity was detected in ospb and ospc and in proteins between 18.0 and 28.0 kda by page. plasmid profiles were heterogeneous in the first isolate from 11 mice (73%) and between the first and last sequential isolate from 13 mice (87%). comparison of the first and last isolates showed increased expressi ... | 1995 | 7622890 |
| relative utilization of reptiles and rodents as hosts by immature ixodes scapularis (acari: ixodidae) in the coastal plain of north carolina, usa. | the interaction of immature black-legged ticks, ixodes scapularis, with reptiles and rodents was investigated in various woodland habitats in the coastal plain of north carolina. reptiles were sampled from april 1 to september 30, 1991. no ticks were found on 95 specimens representing 16 species of snakes. ticks were found on 54 (36.7%) of 147 lizards. i. scapularis was the only tick recovered from lizards. some lizards were collected in drift fence traps each month of the study except august. c ... | 1993 | 7628223 |
| ticks (acari: ixodidae) infesting wild birds (aves) and white-footed mice in lyme, ct. | birds were captured and recaptured (20.8% of 5,297) with japanese mist nets, and white-footed mice, peromyscus leucopus (rafinesque), were caught and recaught (69.1% of 355) with sherman box traps during the late spring, summer, and early fall from july 1989 through october 1991 to study tick-host relationships in lyme, ct. ixodes scapularis say, a vector of lyme disease spirochetes, borrelia burgdorferi sensu stricto johnson, schmid, hye, steigerwalt & brenner, infested 803 birds (15.2%) in 36 ... | 1995 | 7650706 |
| borrelia burgdorferi in eastern virginia: comparison between a coastal and inland locality. | in virginia, borrelia burgdorferi was more prevalent in a site along the atlantic ocean, near maryland, than in an inland site near williamsburg and yorktown. at the coastal site on assateague island, b. burgdorferi was isolated from 4.2% of 475 animals sampled, including four species of small mammals. serologic tests indicated that 25-37% of the small rodents assayed had been exposed to b. burgdorferi. immunofluorescence antibody assays specific for b. burgdorferi showed spirochete infection in ... | 1995 | 7677212 |
| detection of borrelia burgdorferi in tissues of experimentally infected peromyscus leucopus by the polymerase chain reaction. | a polymerase chain reaction (pcr) assay was used to amplify a 158 base pair (bp) dna fragment from the ospa locus of borrelia burgdorferi. this assay could identify all of four distinct b. burgdorferi isolates from oklahoma and could detect as little as 50 x 10(-15) g of purified dna from b. burgdorferi (jd-1) after agarose gel electrophoresis and ethidium bromide staining. the assay was used to detect the lyme spirochete in the heart, liver, spleen, kidney and urinary bladder of four experiment ... | 1993 | 7763705 |
| influence of season and habitat on ixodes scapularis infestation on white-footed mice in northwestern illinois. | the effects of season and habitat on the infestation of the white-footed mouse (peromyscus leucopus) by immature ixodes scapularis were studied at castle rock state park, northwestern illinois, during june-october 1991. relative density of larvae on mice was higher in mid-late summer (13.7 ticks per mouse) than during the rest of the study period, whereas prevalence of nymphal infestation was highest in early summer (33.3%). relative density of i. scapularis larvae and prevalence of nymphs on mi ... | 1994 | 7799148 |
| characteristics of a white-footed mouse (peromyscus leucopus) population inhabiting a polychlorinated biphenyls contaminated site. | demographic characteristics of a white-footed mouse (peromyscus leucopus) population inhabiting a woodland containing a low level of pcbs contamination were compared to an uncontaminated reference site. although population density was higher on the pcbs-contaminated grid, the population exhibited greater temporal variability among years and had a higher number of transient animals. these population trends are consistent with those observed in structurally suboptimal habitats, indicating that the ... | 1994 | 7811110 |
| distribution of borrelia burgdorferi in host mice in pennsylvania. | host mice (peromyscus leucopus and peromyscus maniculatus) were sampled throughout the state of pennsylvania to determine the geographical and ecological distribution of the lyme disease spirochete borrelia burgdorferi. all 67 counties of the state were sampled. a total of 1,619 mice were captured from a total of 157 sites during the period 1990 to 1993 for an overall capture rate of 29.69%. a total of 112 (6.92%) isolations of b. burgdorferi were made. the distribution of isolations revealed th ... | 1994 | 7814489 |
| assignment of tp53 and tk1 to chromosome 13 in peromyscus by fluorescence in situ hybridization. | mus domesticus dna probes for the tumor suppressor protein-53 (tp53) and thymidine kinase-1 (tk1) genetic loci were used to identify clones representing these loci in a peromyscus leucopus (white-footed mouse) cosmid library. the cosmid-derived homologous probes were biotinylated and hybridized to p. maniculatus (deer mouse) chromosomes. probes for both genes hybridized to the chromosome 13 pair identified by prior g-banding. deer mouse chromosome 13 shares a region of homology with mouse chromo ... | 1995 | 7835097 |
| brevinema andersonii gen. nov., sp. nov., an infectious spirochete isolated from the short-tailed shrew (blarina brevicauda) and the white-footed mouse (peromyscus leucopus). | a spirochete which infects short-tailed shrews (blarina brevicauda) and white-footed mice (peromyscus leucopus) has been shown previously to be ultrastructurally and serologically distinct from other spirochetes. two of the original isolates from connecticut and minnesota and 16 new isolates obtained from shrews captured in minnesota were characterized phenotypically and genetically in this study. a comparative analysis of the 16s rrna sequences of two shrew isolates and one mouse isolate and th ... | 1995 | 7857811 |
| effect of deer exclusion on the abundance of immature ixodes scapularis (acari: ixodidae) parasitizing small and medium-sized mammals. | effects of deer exclusion on abundance of immature ixodes scapularis say parasitizing small and medium-sized mammals, and the role mammals have in introducing ticks to exclosure areas, were examined at two sites in westchester county, new york. in total, 686 mammal captures representing nine species were obtained, with white-footed mice, peromyscus leucopus rafinesque, composing > 80% of all captures, followed by raccoons, procyon lotor (l.); opossums, didelphis virginiana (kerr); and striped sk ... | 1995 | 7869342 |
| coccidian parasites (apicomplexa) from snakes in the southcentral and southwestern united states: new host and geographic records. | four hundred thirty-five leptotyphlopid, colubrid, elapid, and viperid snakes were collected from various localities in arkansas, new mexico, oklahoma, and texas, and their feces were examined for coccidian parasites. of these, 131 (30%) were passing oocysts or sporocysts of at least 1 coccidian; 88 (67%) of the infected snakes had only 1 species of coccidian when they were examined. aquatic and semiaquatic snakes accounted for 48% of the infections, whereas strictly terrestrial snakes comprised ... | 1995 | 7876980 |
| detection of borrelia burgdorferi dna in museum specimens of peromyscus leucopus. | to determine whether borrelia burgdorferi was enzootic within the united states at the beginning of the 20th century, ear skin samples taken from museum specimens of the white-footed mouse (peromyscus leucopus) were examined for evidence of spirochetal dna. in total, 280 samples from mice collected between 1870 and 1919 were analyzed by a nested polymerase chain reaction protocol. of these, 2 specimens from the vicinity of dennis, massachusetts, during 1894 were reproducibly positive for b. burg ... | 1994 | 7930700 |
| genetic, phenotypic, and behavioral variation in north american sylvatic isolates of trichinella. | two restriction endonucleases (cla i and hpa ii) produced polymorphic repetitive dna profiles which were used in a clustering analysis to quantify the level of genetic variation among 14 north american sylvatic isolates of t5 trichinella. differences in genetic profiles reflected phenotypic differences in parasite reproductive success as measured by an isolate's reproductive capacity index in natural hosts. two genetically distinct isolates of the t5 genotype and t. spiralis were used to infect ... | 1994 | 7931904 |
| an experimental study of inbreeding depression in a natural habitat. | inbreeding is known to lead to decreased survival and reproduction in captive populations of animals. it is also important to know whether inbreeding has deleterious effects in natural habitats. an estimate was made of the effects of inbreeding in white-footed mice, peromyscus leucopus noveboracensis, derived from a wild population. this study demonstrates that inbreeding had a significant detrimental effect on the survivorship of mice reintroduced into a natural habitat. this effect was more se ... | 1994 | 7939661 |
| isolation of pathogenic hantavirus from white-footed mouse (peromyscus leucopus) | 1994 | 7984010 | |
| parasitic arthropods of white-footed mice at mcclintic wildlife station, west virginia. | seven species of parasitic arthropods (one sucking louse, one bot, 2 fleas, one tick, and 2 mites) were recovered from 81 white-footed mice, peromyscus leucopus, live-trapped on the grounds of the mcclintic wildlife station, mason county, wv, from march through november 1990. the most commonly collected arthropods were the fleas orchopeas leucopus (89 specimens) and epitedia wenmanni (23), and the tick dermacentor variabilis (38). sex ratios for both flea species were female biased; 1.8:1.0 for ... | 1994 | 8014620 |
| experimental borrelia burgdorferi infection in peromyscus leucopus. | we evaluated the susceptibility of laboratory-reared adult and infant white-footed mice (peromyscus leucopus) to a known pathogenic isolate of borrelia burgdorferi (n40). two-month-old and 3-day-old peromyscus were inoculated intradermally with 10(6) to 10(7) spirochetes. at 21 days for adults or 30 days for infants post inoculation, mice were killed, and tissues were cultured for spirochetes and examined microscopically. based on serology and culture, adult mice became infected but did not have ... | 1994 | 8028098 |
| comparison of different strains of borrelia burgdorferi sensu lato used as antigens in enzyme-linked immunosorbent assays. | eight strains of borrelia burgdorferi sensu lato were tested with serum samples from persons who had lyme borreliosis or syphilis in class-specific enzyme-linked immunosorbent assays (elisas). antigens of b. burgdorferi sensu stricto, of borrelia garinii, and of borrelia spirochetes in group vs461 were prepared from cultured bacteria isolated from ticks, a white-footed mouse (peromyscus leucopus), or human tissues in north america, the former soviet union, and japan. nearly all of the serum spec ... | 1994 | 8051239 |
| ticks (acari: ixodidae) collected from small and medium-sized kansas mammals. | seven species of hard-bodied ticks were collected from 20 species of small and medium-sized mammals in kansas; amblyomma americanum l., dermacentor variabilis (say), haemaphysalis leporispalustris (packard), ixodes cookei packard, i. kingi bishopp, i. sculptus neumann, and i. texanus banks. dermacentor variabilis was found statewide, a. americanum only in the eastern one-third of the state, and the ixodes spp. and h. leporispalustris were widely scattered. the most common tick found was d. varia ... | 1994 | 8057327 |
| comparison of chromosomal distribution of a retroposon (line) and a retrovirus-like element mys in peromyscus maniculatus and p. leucopus. | chromosomal distribution for two interspersed elements (lines and mys) that are thought to have established their chromosomal position primarily by transposition was compared between two species of deer mice (peromyscus leucopus and p. maniculatus). both lines and mys generally produced an autosomal banding pattern reflective of g-bands and both hybridized preferentially to the sex chromosomes. the pattern on the long arm of the x was unique for each, with mys reflecting the g-bands (four bands ... | 1994 | 8069462 |
| failure of cryptorchidism to suppress fertility in a tropical rodent. | the cane mouse (zygodontomys brevicauda) breeds year-round on the hot llanos of venezuela, only 8 degrees above the equator. the reproductive responses of the males of this species to heat were compared with those of a temperature zone rodent, the white-footed mouse (peromyscus leucopus). when tested at different ambient temperatures, the movement of the testis in relation to the scrotum was similar in the two species, but the cane mouse's testis proved to be much more resistant to maintenance a ... | 1993 | 8100454 |
| correlative analysis of heavy metal bioconcentration and genetic damage in white-footed mice (peromyscus leucopus) from a hazardous waste site. | 1994 | 8186636 | |
| suppression of ixodes scapularis (acari: ixodidae) nymphs in a large residential community. | to determine the feasibility of suppressing ixodes scapularis say populations in a large, hyperendemic residential community, several rates of granular carbaryl were applied by ground and air to the shrub layer and wooded buffers of a forested residential community during the peak activity period of nymphs. granular carbaryl significantly reduced the abundance of i. scapularis nymphs on peromyscus leucopus raphinesque. control nymphal ticks ranged between 70.0 and 90.3%. the use of properly time ... | 1994 | 8189411 |
| detection of borrelia burgdorferi in urine of peromyscus leucopus by inhibition enzyme-linked immunosorbent assay. | an inhibition enzyme-linked immunosorbent assay was developed to detect borrelia burgdorferi, the etiologic agent of lyme borreliosis, in urine from white-footed mice (peromyscus leucopus). of the 87 urine specimens tested from 87 mice collected in widely separated tick-infested sites in connecticut, 57 (65.5%) contained detectable concentrations of spirochetal antigens. forty-seven (62.7%) of 75 serum samples analyzed contained antibodies to b. burgdorferi. in culture work with tissues from bla ... | 1994 | 8195393 |
| biochemical correlates of longevity in two closely related rodent species. | the objective of this study was to explore the basis of variations in the life span and metabolic potential, i.e., total amount of energy consumed during life, between different species, in context of the free radical hypothesis of aging. a comparison was made between the house mouse (mus musculus) and the white-footed mouse (peromyscus leucopus): the latter has > 2-fold greater life span and metabolic potential than the former. longer life span and higher metabolic potential of peromyscus were ... | 1993 | 8216337 |
| granulocytic leukemia and uterine adenocarcinoma in a white-footed mouse (peromyscus leucopus). | 1993 | 8231099 | |
| experimental infection of the eastern chipmunk (tamias striatus) with the lyme disease spirochete (borrelia burgdorferi). | lyme disease, caused by the spirochete borrelia burgdorferi, is endemic in the northeast, north-central, and pacific coastal states of the united states. the eastern chipmunk (tamias striatus) is found throughout the disease-enzootic regions except along the pacific coast, and may serve as an important reservoir host in some locations. to characterize their potential as a host, 11 adult chipmunks were inoculated with 10(5) spirochetes from strains of b. burgdorferi isolated from peromyscus leuco ... | 1993 | 8258849 |
| reduced abundance of ixodes scapularis (acari: ixodidae) with exclusion of deer by electric fencing. | to assess the effect of deer exclusion on populations of ixodes scapularis say (formerly i. dammini spielman, clifford, piesman & corwin) in the northeastern united states, host-seeking ticks and ticks on white-footed mice, peromyscus leucopus (rafinesque), were monitored inside and outside a wooded, residential deer exclosure (approximately 3.5 ha) in lyme, ct, in 1991 and 1992. another deer exclosure was added in lyme (approximately 7.4 ha) during 1992. additional sample sites at other residen ... | 1993 | 8271257 |
| coat color genetics of peromyscus: iii. golden-nugget--a recessive trait in the white-footed mouse, p. leucopus. | a novel pelage color variant appeared in a laboratory colony of white-footed mice (peromyscus leucopus) from massachusetts. the mature adult coat color of this variant exhibits a rich golden tan appearance on the dorsum with white underparts. the trait is inherited as an autosomal recessive. phenotypic comparisons with other rodents suggest that the trait is attributable to an allele at the brown (b) locus. under laboratory conditions homozygous or heterozygous golden-nugget peromyscus do not di ... | 1993 | 8340620 |
| down-regulation of muscarinic receptors and the m3 subtype in white-footed mice by dietary exposure to parathion. | the effect of ad libitum dietary exposure (as occurs in the field) to parathion for 14 d was investigated on the muscarinic acetylcholine receptor (machr) in brains and submaxillary glands of adults of a field species, the white-footed mouse peromyscus leucopus. immunoprecipitation using subtype selective antibodies revealed that the relative ratios of the m1-m5 machr subtypes in peromyscus brain were similar to those in rat brain. there was little variability in acetylcholinesterase (ache) acti ... | 1993 | 8350385 |
| norway rats as reservoir hosts for lyme disease spirochetes on monhegan island, maine. | to determine whether the agent of lyme disease, borrelia burgdorferi, may be maintained in the absence of its usual white-footed mouse reservoir host, ixodes dammini ticks from an island where mice are absent were examined. prevalence of spirochetal infection was described for ticks removed from mammals, birds, and vegetation on monhegan island, maine. forty percent of adult i. dammini removed from vegetation were infected. norway rats were heavily infested with ticks, and > 60% of such ticks co ... | 1993 | 8354910 |
| isolation and characterization of borrelia burgdorferi from blood of a bird captured in the saint croix river valley. | field investigations were conducted to further evaluate the role of birds in the maintenance and dissemination of borrelia burgdorferi. blood specimens were taken from 39 passerine birds of 17 species captured during june 1991 at the saint croix national riverway in wisconsin, and one isolate, wi91-23, was cultured from an adult song sparrow (melospiza melodia). this isolate was shown to be infectious for peromyscus leucopus and mesocricetus auratus (golden hamster). isolate wi91-23 was confirme ... | 1993 | 8370728 |
| genome organization of repetitive elements in the rodent, peromyscus leucopus. | to document the frequency and distribution of repetitive elements in peromyscus leucopus, the white-footed mouse, a cosmid genomic library was examined. two thousand thirteen randomly chosen recombinants, with an average insert size of 35 kb and representing 2.35% of the haploid genome of p. leucopus, were screened with probes representing microsatellites, tandem repeats, and transposable elements. of the four dinucleotides, (gt)n was present in 87% of the clones, (ct)n was present in 59% of the ... | 1993 | 8395263 |
| reduced abundance of immature ixodes dammini (acari: ixodidae) following incremental removal of deer. | the abundance of immature ixodes dammini spielman, clifford, piesman & corwin was monitored for 9 yr (1983-1991) before and during the controlled, limited hunting of white-tailed deer, odocoileus virginianus (zimmerman), at a coastal massachusetts site. deer abundance was reduced from an estimated 350 during 1985 to approximately 60 during 1991. although annual fluctuations were large, mean larval i. dammini abundance declined from 20.8 per white-footed mouse, peromyscus leucopus (rafinesque), d ... | 1993 | 8433321 |
| reservoir competence of white-footed mice for babesia microti. | although the white-footed mouse, peromyscus leucopus rafinesque, has been incriminated as the main reservoir of the agent of human babesiosis, babesia microti franca, a quantitative demonstration of reservoir competence has not been presented. mice captured within an intensely zoonotic site served as host for laboratory-reared larval ixodes dammini spielman, clifford, piesman, and corwin, and the resulting nymphal ticks were assayed for evidence of salivary gland infection by the piroplasm. sole ... | 1993 | 8433329 |
| role of the eastern chipmunk as a host for immature ixodes dammini (acari: ixodidae) in northwestern illinois. | infestation of the eastern chipmunk, tamias striatus l., by immature ixodes dammini spielman, clifford, piesman and corwin was studied in castle rock state park in northwestern illinois during june-october 1991. mean larval density peaked in august, while nymphal density declined steadily through the study period. prevalence of tick infestation was high throughout the trapping period. tick distribution on chipmunks was aggregated in most of the sampling periods. levels of i. dammini infestation ... | 1993 | 8433349 |
| comparison of the lateral diffusion constant of hepatocyte membrane proteins in two wild mouse strains of considerably different longevity: frap studies on liver smears. | the liver cells of male and female wild mice (peromyscus leucopus and mus musculus) have been studied in young, adult, and old age groups. because p. leucopus displays a life expectancy of 7-8 years, the age groups of this strain were from 5.5 to 68 months. m. musculus survives only to about 2.5 years; therefore, the age groups of this strain ranged from 6 to 27 months. protein lateral diffusion in hepatocyte membranes was measured by means of fluorescence recovery after photobleaching (frap) in ... | 1993 | 8482810 |
| experimental borrelia burgdorferi infections in the white-footed mouse, deer mouse, and fulvous harvest mouse detected by needle aspiration of spirochetes. | three methods were tested for recovering borrelia burgdorferi from live mice onto bsk ii culture medium. four laboratory-reared peromyscus leucopus were inoculated intraperitoneally with the jd-1 isolate of borrelia burgdorferi. borrelia burgdorferi spirochetes were recovered from 13 of 20 (65%) samples taken by needle aspiration between days 7 and 40 post-inoculation (pi) and from 1 of 16 samples of skin obtained by ear punch biopsy during the same sampling period. spirochetes were not recovere ... | 1993 | 8487370 |
| age- and gender-related variations in the activities of drug-metabolizing and antioxidant enzymes in the white-footed mouse (peromyscus leucopus). | the effects of aging on the activities of drug-metabolizing enzymes and antioxidant enzymes were studied in male and female white-footed mice (peromyscus leucopus) at ages of 6, 8, 12, 18, 24, 30, 36, and 48 months. male mice had significantly higher liver microsomal cytochrome p450 (p450) content and nadph:cytochrome p450 oxidoreductase (p450 reductase) activities than females at all age groups. many of the p450-dependent enzyme activities were also generally higher in males. female mice showed ... | 1993 | 8495997 |
| regional analysis of 5-ht1a receptors in two species of peromyscus. | two species of deer-mice, peromyscus maniculatus (p. man) and peromyscus leucopus (p. leu), were compared for differences in 5-hydroxytryptamine1a (5-ht1a) receptor number and affinity. both species enter into torpor; however, p. man enters spontaneous torpor with a higher frequency and for a longer duration than p. leu. further, compared to p. leu a higher percentage of p. man exhibit daily torpor. deer mice can be induced to enter torpor by a reduction in food supply, shortened photoperiods, a ... | 1993 | 8516353 |
| larval density and feeding success of ixodes scapularis on two species of peromyscus. | one potential mechanism for the regulation of tick populations is density-dependent feeding success on vertebrate hosts. in a series of laboratory experiments, we tested whether the density of larval ixodes scapularis on the mice peromyscus maniculatus and peromyscus leucopus influenced tick feeding success. for both host species, the proportion of ticks feeding to repletion was constant (approximately 40-50%) over a range of infestation from 5 to 100 ticks per mouse. for p. leucopus, neither ma ... | 1995 | 8544056 |
| retrotransposon mys was active during evolution of the peromyscus leucopus-maniculatus complex. | mys is a retrovirus-like transposable element found throughout the genus peromyscus. several mys subfamilies identified on the basis of restriction site variation occur in more than one species. the distribution of these subfamilies is consistent with the accepted species phylogeny, suggesting that mys was present in the ancestor of peromyscus and has been active through much of the evolution of this genus. quantitative southern blot analysis was used to examine the variability of subfamilies in ... | 1996 | 8576963 |
| analyses of mammalian sera in enzyme-linked immunosorbent assays with different strains of borrelia burgdorferi sensu lato. | blood samples were collected from cottontail rabbits (sylvilagus floridanus), raccoons (procyon lotor), white-footed mice (peromyscus leucopus), and white-tailed deer (odocoileus virginianus) between 1977 and 1991 in southern connecticut and new york state (usa) and were tested for antibodies against eight strains of borrelia burgdorferi sensu lato in enzyme-linked immunosorbent assays. among these spirochetes were six strains of b. burgdorferi sensu stricto, one strain of b. garinii (=ip90) and ... | 1995 | 8583632 |
| reactivity of white-footed mouse and raccoon sera to whole cell and recombinant antigens of borrelia burgdorferi. | serum samples were collected from white-footed mice (peromyscus leucopus) and raccoons (procyon lotor) during 1983, 1984, and 1990 through 1993 in connecticut (usa) and were tested in enzyme-linked immunosorbent assays (elisa) against whole cell borrelia burgdorferi sensu stricto (strain 2591) and the following recombinant antigens of this spirochete: p41-g (an immunogenic epitope of flagellin), outer surface protein (osp)a, and ospb. antibodies were most frequently detected when whole cell anti ... | 1995 | 8592354 |
| ear biopsy location influences detection of borrelia burgdorferi by pcr, but not by culture in naturally infected peromyscus leucopus. | we determined if the ear biopsy location affected detection of borrelia burgdorferi when either culture or the polymerase chain reaction (pcr) was used among 50 white-footed mice (peromyscus leucopus), live-captured in a lyme disease enzootic area in maryland (usa) between march and october of 1991 and 1992. the infection status of individual mice was determined by organ culture; ear biopsy samples were obtained from the peripheral and central part of the ear for detection of b. burgdorferi by c ... | 1995 | 8592355 |
| experimental infection of the red-backed vole (clethrionomys gapperi) with borrelia burgdorferi. | red-backed voles (clethrionomys gapperi) were live trapped in northern st. louis county, minnesota (usa), in late september and october 1988 and experimentally inoculated with borrelia burgdorferi. spirochetes were isolated from most animals 14 and 28 days following inoculation. thus, red-backed voles exposed to b. burgdorferi were susceptible to infection and could be a reservoir host, along with chipmunks (tamias striatus) and other small rodents, in areas where white-footed mouse (peromyscus ... | 1995 | 8592371 |
| the uptake and effects of lead in small mammals and frogs at a trap and skeet range. | this study was performed to evaluate the bioavailability and effects of lead in wildlife at a trap and skeet range. the total lead concentration in a composite soil sample (pellets removed) was 75,000 micrograms/g dry weight. elevated tissue lead concentrations and depressed alad activities in small mammals and frogs indicate that some of the lead deposited at the site is bioavailable. mean tissue lead concentrations (micrograms/g dry wt.) in white-footed mice (peromyscus leucopus) at the range ... | 1996 | 8593083 |
| histopathology of peromyscus leucopus naturally infected with pathogenic ny-1 hantaviruses: pathologic markers of hps viral infection in mice. | hantavirus research is impeded by the absence of animal models of viral pathogenesis. we have studied the histopathology of mice (p. leucopus) naturally infected with the ny-1 hantavirus on shelter island, new york. five mice were determined to be seropositive in western blotting to four corners virus nucleocapsid protein and had serum antibodies to seoul and puumala hantavirus antigens by immunofluorescence assay. hantavirus gene segments of the ny-1 hantavirus were identified in these mice and ... | 1996 | 8600313 |
| field estimates of numbers of ixodes scapularis (acari:ixodidae) larvae and nymphs per hectare successfully feeding on peromyscus leucopus in massachusetts. | the numbers of blacklegged tick, ixodes scapularis say, per hectare that engorged as larvae and nymphs on white-footed mice, peromyscus leucopus (rafinesque), were estimated at 3 sites in coastal massachusetts. estimates of numbers of engorged ticks dropping per day from trapped mice were multiplied by mark-recapture estimates of the density (numbers per hectare) of white-footed mice to estimate numbers of ticks engorging on mice per hectare. in 1991, estimates of seasonal totals per hectare of ... | 1996 | 8840688 |
| spread of ixodes scapularis (acari:ixodidae) in indiana: collections of adults in 1991-1994 and description of a borrelia burgdorferi-infected population. | collection records for the adult black legged tick, ixodes scapularis say, in indiana for the period 1991-1994 are presented and a new, established population of borrelia burgdorferi-infected i. scapularis is described. the number of i. scapularis adults collected in indiana increased progressively from 19 in 1991 to > 200 in 1994, and the number of indiana counties reporting at least 1 adult increased from 13 to 29. also, during this period, 4 countries in northwestern indiana yielded > 10 spec ... | 1996 | 8840696 |
| entomological correlates of babesia microti prevalence in an area where ixodes scapularis (acari:ixodidae) is endemic. | zoonotic prevalence of babesia microti franca piroplasms infecting white-footed mice, peromyscus leucopus rafinesque, was determined at 34 sites in rhode island where nymphal blacklegged tick, ixodes scapularis say, densities ranged from low to hyperabundant (1.7-525.3 nymphs per hour of flagging). babesia was only detected at sites where tick abundance was moderate to high (> 20 nymphs per hour of flagging) and appeared to exhibit a clumped distribution. where b. microti was detected, the mean ... | 1996 | 8840700 |
| sequence analysis of the complete s genomic segment of a newly identified hantavirus isolated from the white-footed mouse (peromyscus leucopus): phylogenetic relationship with other sigmodontine rodent-borne hantaviruses. | four corners (fc) or sin nombre virus, a hantavirus harbored by the deer mouse (peromyscus maniculatus), is the principal etiologic agent of hantavirus pulmonary syndrome (hps). recently, a hantavirus, designated new york (ny) virus, isolated from a white-footed mouse (peromyscus leucopus) captured on shelter island, new york, was molecularly linked to a fatal case of hps occurring in the northeastern united states. to clarify the genetic and phylogenetic relationship between ny and fc viruses a ... | 1996 | 8883362 |
| interspecific differences between small mammals as hosts of immature dermacentor variabilis (acari: ixodidae) and a model for detection of high risk areas of rocky mountain spotted fever. | fourteen species of small mammals were captured from july 1990 through august 1991 in tennessee, from which 1,217 immature dermacentor variabilis and 1 ixodes dentatus were collected. mammal species were given scores of importance (ts) as hosts to immature d. variabilis based on mean intensity and prevalence. the rice rat ranked the highest, with a ts = 5, followed by the golden mouse ts = 4, white-footed mouse ts = 3, pine vole ts = 2, cotton rat ts = 1, with the norway rat, house mouse, and sh ... | 1996 | 8885876 |
| hantavirus s rna sequence from a fatal case of hps in new york. | in april, 1995, the second fatal case of hantavirus pulmonary syndrome (hps) occurred in the northeast in a new york state resident. using the patient's lung tissue obtained at autopsy, the s genomic rna segment of a hantavirus, designated h-ny1, was amplified by reverse transcriptase-polymerase chain reaction (rt-pcr), cloned, and sequenced. the s rna was found to contain 2084 nucleotides, 6 nucleotides longer than reported by hjelle et al. (1995) for the virus associated with the first northea ... | 1996 | 8890033 |