Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [immunologic aspects of pneumocystis carinii pneumonia in the adult]. | 1976 | 1085397 | |
| [pneumocystis carinii pneumonias in the adult]. | 1976 | 1085398 | |
| trimethoprim-sulfamethoxazole treatment of pneumocystis carinii pneumonia in adults. | 1976 | 1085413 | |
| editorial: treatment of pneumocystis carinii pneumonitis. | 1976 | 1085414 | |
| unusual roentgenographic manifestation of pneumocystis carinii pneumonia. | an immunologically deficient patient had two large nodular densities on the chest x-ray film. on autopsy, large solid accumulations and diffuse pneumonitis with pneumocystis carinii were found. this represents an unusual manifestation of pneumocystis carinii. | 1976 | 1085688 |
| [pneumocystis carinii pneumonia associated with stomach neoplasm and liver cirrhosis--an autopsy study and statistical observation]. | 1976 | 1085829 | |
| pneumocystis carinii pneumonia. | 1976 | 1086376 | |
| [diagnosis of pneumocystic carinii pneumonia by lavage of the bronchial system (author's transl)]. | this report deals with a 10 year old girl suffering from an acute lymphoblastic leukemia since 1971. the child was hematologically in full remission, when she developed a pneumonia due to pneumocystis carinii. the diagnosis was established by demonstrating the agent in bronchial secretions. the material was obtained by rinsing the bronchial system. the patient was treated with pentamidine and co-trimoxazol (bactrim) with good success. | 1976 | 1086403 |
| microtubules in pneumocystis carinii. | 1976 | 1086555 | |
| [assessment of the respiratory system in children following pneumocystis carinii pneumonia]. | 1976 | 1087402 | |
| [parasites of the respiratory system: research and significance (author's transl)]. | a review is made of the methods of diagnosing both autochthonous and exotic protozoal and helminthic diseases of the respiratory system. referring to protozooses, recent findings on respiratory pathology due to amoebae of the genus acanthamoeba are commented, and modern methods are discussed of checking for pneumocystis carinii in the patient, not just on autopsy material. referring to helminthiases, in addition to pulmonary echinococcosis which is of prevalent interest in italy, attention is al ... | 1976 | 1087869 |
| transbronchial lung biopsy via the fiberoptic bronchoscope in the diagnosis of diffuse pulmonary infiltrates in the immunosuppressed host. | the differential diagnosis of diffuse pulmonary infiltrates in the immunosuppressed patient is broad. many of the etiologies are amenable to specific therapy. although endobronchial brush biopsy has been used to identify many infections, including pneumocystis carinii, it was less effective in the diagnosis of noinfectious infiltrates. transbronchial lung biopsy via the fiberoptic bronchoscope provided lung tissue that could be studied histologically, which increased the diagnostic yield without ... | 1976 | 1087949 |
| percutaneos pulmonary needle diagnosis of pneumocystis carinii pneumonitis. | percutaneous pulmonary needle aspiration (pc-a) is one of several diagnostic techniques capable of providing material in which pneumocystis carinii organisms can be identified. this simple procedure, readily performed by most physicians, can be rapidly done under local anesthesia, requiring no sedation, general anesthetic, or multiple support personnel. when the chest roentgenographic evidence suggests diffuse involvement, pc-a may be performed at the bedside; if more patchy in distribution, und ... | 1976 | 1087950 |
| open lung biopsy in the diagnosis of pneumocystis carinii pneumonia. | lung biopsy remains the essential cornerstone in the diagnosis of pneumocystis pneumonia. whatever technique can establish this diagnosis safely and early in order to get treatment started quickly should be used. open lung biopsy remains a candidate for the diagnostic method of choice because if offers some advantages over percutaneous needle biopsy. there is a greater supply of competent thoracic surgeons in most hospitals than of physicians who are proficient with needle biopsy. the direct vis ... | 1976 | 1087951 |
| pneumocystis carinii infection: diagnosis and pathogenesis. | the methods of diagnosis of pneumocystis carinii infection are reviewed; a high index of suspicion of the disease, particularly in the immunodeficient patient, is stressed and the classic morphology of the organism is described. discussed are the known immunologic features gleaned from clinical and pathologic data from the literature and the reported cases from the university of minnesota hospitals. the importance of the complete investigation of the immune status of every patient who develops p ... | 1976 | 1087952 |
| cytologic diagnosis of pneumocystis carinii. | 1976 | 1087953 | |
| pulmonary and extrapulmonary support for patients with pneumocystis carinii pneumonia. | temporary extrapulmonary oxygenation may benefit selected patients with pneumocystis carinii pneumonia who exhibit severe respiratory insufficiency. four persons were considered candidates for extrapulmonary oxygenation with a membrane lung while under treatment for pneumocystis pneumonia. in one patient, attempts to institute membrane lung circulation were postponed until his condition was terminal. in another individual, membrane lung support was discontinued prematurely because of complicatio ... | 1976 | 1087954 |
| treatment of pneumocystis carinii pneumonia: current status of the regimens of pentamidine isethionate and pyrimethamine-sulfadiazine. | a randomized clinical trial is under way comparing the relative merits of pentamidine isethionate and pyrimethamine-sulfadiazine in the management of patients with pneumocystis carinii pneumonia. twenty-one patients have entered the trial. both regimens have produced at least one complete recovery in biopsy-proved pneumocystis pneumonia. two patients have died from pneumocystis pneumonia after being treated with a combination of both regimens. initial observations on comparative toxicity indicat ... | 1976 | 1087955 |
| treatment of pneumocystis carinii pneumonia in infancy. | pentamidine is recommended for the therapy of pneumocystis carinii pneumonia either alone or, in severe cases, combined with pyrimethamine. attention is drawn to the importance of supporting symptomatic treatment, particularly with the promethazine-hydergine cocktail, and to the possibilities for general and drug prophylaxis. | 1976 | 1087956 |
| endemic infantile pneumocystis carinii infection: the shiraz study. | orphanage epidemics of interstitial plasma cell pneumonia (ipcp) occur among premature infants whose passive immunity due to maternally transferred antibodies has lost its effectiveness before the infants' humoral immune systems have reached sufficient maturity to respond effectively to pneumocystis carinii. ipcp occurs also among mature newborns receiving substandard care in understaffed and crowded orphanages. infantile diarrhea in these institutions leads to marasmus and deficient immune resp ... | 1976 | 1087958 |
| pneumocystis carinii pneumonia in the united states: epidemiologic, diagnostic, and clinical features. | analysis of 194 patients with confirmed pneumocystis carinii pneumonia in the united states over a 3-year period revealed that p. carinii pneumonia occurred almost exclusively in the immunosuppressed host who had a serious underlying disease. the epidemiologic features of pneumocystis pneumonia primarily reflected those of the underlying disease. p. carinii was identified antermortem in 81% of the cases usually by biopsy or needle aspiration of the lung, procedures associated with considerable m ... | 1976 | 1087960 |
| pneumocystis carinii pneumonia and primary immune deficiency diseases. | during a 3-year period, 50 cases of pneumocystis carinii pneumonia in children less than 5 years old were reported to the parasitic disease drug service, center for disease control. primary immune deficiency diseses constituted the most frequent underlying diseases in patients less than 1 year old (24/29 cases, 83%), whereas acute lymphatic leukemia was the most common underlying diseases in children 1-4 years old (17/21 cases, 81%). severe combined immunodeficiency was the most common type of i ... | 1976 | 1087961 |
| atypical radiographic features in pneumocystis carinii pneumonia. | in a review of clinical, pathologic, and radiographic findings from 30 patients with confirmed pneumocystis pneumonia, the disease presented a typical radiographic picture of acute bilateral perihilar and basilar infiltrate progressing to diffuse alveolar consolidation within 3-5 days and unassociated with adenopathy or pleural changes in 13 patients. however, the incidence of atypical radiographic features was appreciable (17 of the 30 patients showed at least one atypical finding) and, in addi ... | 1976 | 1087962 |
| pneumocystis carinii pneumonia in children with acute leukemia. | 1976 | 1088423 | |
| pulmonary granulomatous pneumocystosis following renal transplantation. report of a case. | pulmonary granulomas of sarcoid type in a patient who was on long-term immunosuppressive therapy following renal transplantation are described. pneumocystis carinii was identified within the lesions. this is believed to be the first description of this type of reaction to pneumocystis in the adult patient on immunosuppressive therapy. | 1975 | 1090147 |
| [pneumocystis carinii pneumonia after kidney transplantation. early diagnosis by distal bronchial brushing]. | distal bronchial brushing is one of the methods used in the in vivo indentification of pneumocystis carinii, a parasite associated with severe pneumonia, the development of which is induced by immuno-depression, particularly after renal transplantation. in three patients the pathogenic agent was demonstrated in alveolar material obtained in this way. the technique is simple and risk-free. it may be used early and repeatedly. | 1975 | 1093127 |
| pneumocystis carinii pneumonia: a cluster of eleven cases. | an unusual cluster of 11 patients with pneumocystis carinii pneumonia occurred in a 3-month period at memorial hospital, new york. ten of the 11 patients had lymphoma or leukemia. in 7 patients, corticosteroid therapy was decreased or stopped shortly before pneumocystis pneumonia was diagnosed. the pediatric patients had extensive contact in the outpatient department, and three of them had roomed together, suggesting the possibility of man to man transmission. tree of 4 adult patients with hodgk ... | 1975 | 1094880 |
| letter: roentgenographically atypical pneumocystis carinii pneumonia. | 1975 | 1098535 | |
| [laboratory diagnosis of pneumocystis carinii: comparison of cytological, immunofluorescent and immunocytochemical staining]. | authors review several methods for diagnosis of pneumocystis carinii on bal fluid in aids patients aiming to identify ideal routine technic. giemsa, gomori and toluidine blue staining. direct and indirect immunofluorescence. immunocytochemical methods were tested and advantages/disadvantages compared on bal fluid from aids patients. pneumocystis carinii was detected in 7 out 21 cases (33%). gomori staining and toluidine blue staining were chosen for routine pneumocystis carinii detection while i ... | 1992 | 1279508 |
| phenotypic analysis of bronchoalveolar lavage lymphocytes from acquired immunodeficiency patients with and without pneumocystis carinii pneumonia. | a study was performed to reveal possible differences in lymphocyte subpopulations from bronchoalveolar lavage (bal) of acquired immunodeficiency patients with and without pneumocystis carinii pneumonia. forty-one consecutive human immunodeficiency virus-seropositive patients were studied. pneumocystis carinii infection was detected in the bal fluid from 18 patients. the bal lymphocyte subpopulations were determined by surface marker analysis with the immunoperoxidase slide assay. no significant ... | 1992 | 1280389 |
| purification of pneumocystis carinii trophozoites and identification of their circulating antigens. | we have developed a new method to isolate pneumocystis carinii trophozoites from experimental rat bronchoalveolar lavage specimens by using a percoll discontinuous gradient and have identified the circulating antigens in experimental rat p. carinii pneumonia. the antigenic components of the trophozoites were compared with those of cysts by immunoblotting. a major immunoreactive band of 90,000 da and some others of lower molecular mass were found in trophozoites. on the other hand, bands of 110,0 ... | 1992 | 1280653 |
| identification of a lectin activity in pneumocystis carinii. | pneumocystitis carinii is known to adhere to pulmonary alveolar epithelial cells in vivo and to epithelial cell lines in vitro by a mechanism unknown at the molecular level. p. carinii is now found to adhere to rabbit and human red blood cells leading to rosette formation and hemagglutination. p. carinii erythrocyte-adherence was best inhibited by bovine submaxillary mucin and by a polysaccharide from the wall of group a streptococcus, and to a lesser extent by streptococcus group c polysacchari ... | 1992 | 1281927 |
| treatment of aids-related non-hodgkin's lymphoma with a twelve week chemotherapy program. | current treatment options for acquired-immunodeficiency syndrome (aids)-related non-hodgkin's lymphoma (nhl) are unsatisfactory because of excessive toxicity rates and frequent recurrence of lymphoma. in this phase ii study, we evaluated a novel 12 week chemotherapy program with respect to feasibility, toxicity and therapeutic results. thirty hiv-seropositive patients with intermediate grade or small non-cleaved cell nhl received a 12 week program of weekly intravenous and oral chemotherapy cons ... | 1992 | 1283356 |
| [hiv infection: a case of progressive encephalopathy and pneumocystis carinii pneumonia in a child]. | 1992 | 1283713 | |
| [pneumocystis carinii infection in a hiv infection department]. | to determine the prevalence of pneumocystis carinii in the hiv-infection department, a simultaneous survey was made of 33 hiv-infected patients at various stages of the disease, of close relatives that were nursing the patients in the unit (n-7), and of medical staff of the department (n-20). patients with toxic infections who were on another floor of the same hospital and medical students were examined as a control group. for detection of p. carinii antigen, smears from the deep airways were te ... | 1992 | 1283714 |
| immunohistochemical detection of pneumocystis carinii in transbronchial lung biopsy specimens: antigen difference between human and rat pneumocystis carinii. | transbronchial lung biopsy specimens, from three patients with non-aids-related pneumocystis carinii pneumonia (pcp) and rat lung tissue in which pcp was induced by the administration of dexamethasone, were studied to determine the diagnostic usefulness of an immunohistochemical method using commercially available anti-pneumocystis monoclonal antibody, 3f6, on formalin-fixed, paraffin-embedded tissue. pc was consistently stained a bright red color and unambiguously identified in all three human ... | 1992 | 1283992 |
| [pneumocystis carinii pneumonia: laboratory diagnosis]. | we worked with 51 samples, 7 bronchoalveolar lavages (bal) and 44 sputa (s) of 31 aids patients with clinical and radiographic symptoms compatible with pneumocystis pneumonia. with the aim of finding a specific sensitive methodology for the diagnosis of pneumocystis carinii, we evaluated 4 coloration techniques (silver methenamine, its modification without gold chloride, toluidine blue and giemsa). 35% of the patients studied were positive. p. carinii were observed in 18% of the 44 sputa. we obs ... | 1992 | 1284318 |
| [differential diagnosis of ascites and abscess forming hepatitis in aids patients with reference to the first patient with microsporidia infection in austria]. | we report on a 30 years-old female aids patient suffering from generalized pneumocystosis and intestinal microsporidiosis. the chest x-ray showed a right-sided pleural effusion; the lungs showed no areas of consolidation and the heart and the vessels were normal in size. sonography revealed multiple cystic lesions of the liver measuring 1-3 cm in diameter, as well as ascites. pneumocystis carinii was detected on cytological examination of the bronchoalveolar lavage fluid, the pleural effusion an ... | 1992 | 1288019 |
| improvement of pulmonary gas exchange after surfactant replacement in rats with pneumocystis carinii pneumonia. | the effect of intratracheal surfactant instillation on pulmonary function in rats with pneumocystis carinii pneumonia (pcp) was investigated. in these animals which developed pcp with severe respiratory failure after s.c. administration of cortisone acetate over 8-12 weeks, pulmonary function could be improved by surfactant instillation, as measured by an increase in pao2. histological examination showed that alveoli of rats with pcp which received no surfactant treatment are filled with foamy e ... | 1992 | 1288089 |
| [a case of legionella pneumonia with myelodysplastic syndrome]. | a 40-year-old man was admitted with high fever and cough. pneumonic shadows of the left middle and lower lung fields increased rapidly, and his blood gases worsened. initial treatment with cefmenoxime, piperacillin, and minocycline was ineffective. administration of rifampicin was started for suspected legionella pneumonia, but it did not control the spread of the pneumonia shadows. after addition of an antifungal agent and trimethoprim-sulfamethoxazole, his symptoms gradually improved. isolatio ... | 1992 | 1289632 |
| high dose aerosol pentamidine for secondary pneumocystis carinii pneumonia prophylaxis in aids patients. | in a prospective trial of aerosolized pentamidine as secondary prophylaxis for pneumocystis carinii pneumonia (pcp) 18 patients received 400 mg once weekly for a mean period of 15.5 months. pentamidine aerosol was administered with an ma2 jet nebulizer. no pcp relapses were observed and no serious side effects occurred. | 1992 | 1293048 |
| [infectious complications in patients with adult t-cell leukemia]. | between january, 1982, and january, 1992, a total of 112 patients with adult t-cell leukemia (atl) and 109 patients with non-hodgkin's lymphoma (nhl) were admitted to our hospital. they were studied for their infectious complications. infectious complications were seen in 90 patients (80.4%) with atl, and 51 patients (46.8%) with nhl (p < 0.001). documented infections were seen in 70 patients (62.5%) with atl, and 30 patients (27.5%) with nhl (p < 0.001). pneumonia (p < 0.005), skin infections ( ... | 1992 | 1293224 |
| acquired immunodeficiency syndrome (aids) with lymphocytic interstitial pneumonitis (lip) in a multi transfused child with thalassemia major. | the case of a 10.5-year-old girl, who was diagnosed with a case of thalassemia major at the age of 8 months and had been on regular blood transfusions since then, is related. donor screening for hiv was started in mid-1988, thus she had received unscreened blood for a number of years. in february 1991, she presented with a dry persistent cough, moderate grade continuous fever, and breathlessness on exertion for over 2 weeks. chest x-ray showed bilateral infiltrations. she was put on penicill ... | 1992 | 1294497 |
| [human lymphocyte proliferative response and gamma-interferon production to pneumocystis carinii antigen in vitro]. | in vitro proliferative response and gamma-interferon (ifn-gamma) production to pneumocystis carinii antigen were investigated in peripheral blood mononuclear cells (pbmc) from healthy volunteers and cord blood mononuclear cells (cbmc) from umbilical cords after delivery. twenty three of 25 samples of pbmc had strong proliferative response, and 15 of 25 samples of pbmc produced ifn-gamma. in the samples showing strong proliferative response, cd4 lymphocytes expressed interleukin 2 receptors. none ... | 1992 | 1294671 |
| [pneumocystis carinii pneumonia in a kidney transplantation center in the proximity of an aids care unit]. | 1992 | 1297138 | |
| susceptibility of various animals to pneumocystis carinii infection. | pneumocystis carinii (pc) is an important opportunistic pathogen of immune compromised hosts, and is known to infect various animals. the present study observed the infection status of 6 mammals and 3 strains of albino rats with pc after suppression of their immunity. methyl-prednisolone was injected once a week and tetracycline was supplied with water for 5 to 21 weeks. hamsters, guinea pigs, rabbits, dogs, cats and pigs were negative by impression smear, and only the rats were found infected b ... | 1992 | 1297418 |
| transmission modes of pneumocystis carinii among rats observed by karyotype analysis. | to observe the transmission patterns of karyotype of pneumocystis carinii (pc) by rat colonies, three strains of rats, sprague-dawley(sd), wistar(w) and fisher(f) from various animal vendors, were suppressed of their immunity by injection of methyl prednisolone. they were kept for 5 to 13 weeks in 3 different animal rooms, a, b, and c. the purified organisms were prepared in low melting point agarose gel by embedded lysis method for pulsed field gel electrophoresis. field inversion gel electroph ... | 1992 | 1297419 |
| [liver transplant in childhood: our experience]. | from december 1984 to december of 1991, 12 children underwent on orthotopic liver transplantation (olt): 6 had extrahepatic biliary atresia (ehba), 2 had byler disease, 2 hepatocellular carcinoma (hcc), 1 alagille syndrome and 1 had a hyperacute wilson disease. the children, transplanted for the most part a broad, return for observation 3 months after olt. a patient with hyperacute wilson's disease had 2 emergency olts and died of sepsis (due to aspergillus); another with ehba, operated for hepa ... | 1992 | 1298933 |
| [the pulmonary manifestations in aids]. | clinical and paraclinical experience in hiv infection, though the time elapsed since the first observations is relatively short, begins to get typical outlines. in the case of aids, the lung is the main place of opportunistic infections, other inflammatory processes and neoplasia. the present work deals with six clinical cases with positive serum tests for hiv and secondary respiratory phenomena such as: kaposi sarcoma, pneumonia with pneumocystis carinii, tuberculosis, candidosis, pneumonia wit ... | 1992 | 1299394 |
| pneumocystis carinii pneumonia in patients with systemic lupus erythematosus. | at the university hospital, kuala lumpur, malaysia, nine patients with systemic lupus erythematosus (sle) were treated for pneumocystis carinii pneumonia (pcp) between january 1987 and december 1988. when they developed pcp all the patients' sle disease course was active and eight of them were on prednisolone. four of these eight patients were also receiving cyclophosphamide. patients who were on more intensive immunosuppressive therapy were found to develop more severe pcp. all the patients exc ... | 1992 | 1304406 |
| [isolation and purification of pneumocystis carinii cyst]. | twenty wistar rats were injected with cortisone acetate twice a week subcutaneously for 6-12 wks. by 7 weeks pneumocystis carinii pneumonia was induced in rats successfully. the cysts of pneumocystis carinii from infected lungs of cortisonized rats were identified by phase-contrast microscopy, giemsa's stain, chalvardjian's stain and gomori's methenamine silver nitrate stain. the process of isolation and purification of pneumocystis carinii from infected rat lungs included the following three te ... | 1992 | 1307267 |
| pneumocystis carinii pneumonia prophylaxis: past, present and future. | 1992 | 1307680 | |
| patients' perceptions of pulmonary problems and nursing interventions during hospitalization for pneumocystis carinii pneumonia. | the descriptive, correlational study examined patients' perceptions of pulmonary problems and nursing interventions in a sample (n = 201) of persons living with aids hospitalized for pneumocystis carinii. additionally, the study assessed differences in physiological variables, patient symptoms, and functional status based on the type of problems identified: dyspnea, pulmonary problems without dyspnea, and nonpulmonary problems. | 1992 | 1307871 |
| pneumocystis carinii pneumonia (pcp) in a renal transplant recipient in india. | 1992 | 1308040 | |
| chemotherapy and immunity in opportunistic parasitic infections in aids. | parasitic diseases are endemic in parts of the tropics, but there is no convincing evidence that their prevalence or incidence is increasing due to the hiv epidemic. available scientific data on parasitic infections in patients with the acquired immunodeficiency syndrome (aids) suggests a predominance of pneumocystis carinii, toxoplasma gondii and cryptosporidium spp. for reasons which are unclear, parasitic infections such as plasmodium falciparum, strongyloides stercoralis and entamoeba histol ... | 1992 | 1308934 |
| impact of pneumocystis carinii and cytomegalovirus on the course and outcome of atypical pneumonia in advanced human immunodeficiency virus disease. | patients undergoing bronchoscopy for possible pneumocystis pneumonia were studied retrospectively to characterize the impact of common viral pathogens on the course of advanced human immunodeficiency virus (hiv) disease and atypical pneumonia. in 327 episodes, pneumocystis carinii was found in 220 (67%), cytomegalovirus (cmv) in 145 (44%), and herpes simplex virus in 16 (5%). early deterioration in oxygenation and use of intensive care was less common in cmv-positive patients. neither cmv nor p. ... | 1992 | 1309375 |
| pneumocystis carinii pneumonia. an uncommon cause of death in african patients with acquired immunodeficiency syndrome. | admissions and deaths in a pulmonary medicine ward in abidjan, cote d'ivoire, west africa, were evaluated over a 6-month period in 1989 with systematic autopsies on all patients who died. of 473 patients admitted, 38% were hiv-1 seropositive, 4% were hiv-2 seropositive, and 14% reacted to both viruses. a total of 100 patients (21%) died, and deaths were twice as frequent in hiv-seropositive compared with hiv-negative patients. the pathology of 78 autopsies showed that the predominant cause of de ... | 1992 | 1312314 |
| apparent retrovirus-induced immunosuppression in a yearling llama. | immunosuppression suspected to be associated with retrovirus infection was diagnosed in an 18-month-old female llama. the llama had a 6-month history of weight loss, intermittent lameness, and infections that were nonresponsive to treatment. serial cbc indicated persistent nonregenerative anemia and leukopenia characterized by absolute neutropenia and lymphopenia. functional hypoplasia of myeloid and erythroid cell lines was detected in serial bone marrow biopsy specimens. notable pathologic fin ... | 1992 | 1312520 |
| postoperative respiratory failure secondary to pneumocystis carinii pneumonia. | pneumocystis carinii pneumonia (pcp) occurs frequently in individuals infected with the hiv virus. malignancy, immunosuppressive drugs, and congenital immune deficiency may be associated with pcp. we describe a patient with stage 1 testicular carcinoma who developed hypoxemic respiratory failure two days after retroperitoneal lymph node dissection. pneumocystis carinii organisms were demonstrated by catheter lavage samples and confirmed on bronchoalveolar lavage. testing for hiv antibody by elis ... | 1992 | 1313351 |
| the multifunctional folic acid synthesis fas gene of pneumocystis carinii appears to encode dihydropteroate synthase and hydroxymethyldihydropterin pyrophosphokinase. | we describe the cloning of a multifunctional folic acid synthesis (fas) gene from pneumocystis carinii. the nucleotide sequence contains an open reading frame interrupted by three introns, that encodes a protein of 740 amino acids with an mr of 97,278. the predicted fas protein has homology to two enzyme domains, dihydropteroate synthase and 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, both of which are involved in folate synthesis, and at least one other region of unknown function. | 1992 | 1313386 |
| interactions and toxicities of drugs used in patients with aids. | as clinicians have come to realize, patients who have aids are uniquely predisposed to drug-associated toxic effects and allergic reactions. in san francisco general hospital's first clinical trial involving patients with pneumonia due to pneumocystis carinii, only one-third of all patients who were treated initially with either trimethoprim-sulfamethoxazole or pentamidine were able to complete the 3-week course. because of drug-related toxic effects, most patients required an alteration in ther ... | 1992 | 1314104 |
| gastric uptake of gallium-67 in aids. | we describe gastric localization of 67ga in 13 patients with acquired immunodeficiency syndrome (aids) among 148 referred primarily to rule out pneumocystis carinii pneumonia (pcp). endoscopic biopsies in five of the patients indicated cytomegalovirus (cmv) infection in one, gastritis in two, and normal tissue in two. other associated, but nongastric, infections in these 13 patients included esophageal candidiasis, pcp, mycobacterium avium-intracellulare (mai) complex, coccidioidomycosis, toxopl ... | 1992 | 1314894 |
| lack of clinical evidence for a specific hiv-associated glomerulopathy in 203 patients with hiv infection. | several authors described a high incidence of proteinuria with frequent progression to nephrotic syndrome and/or renal failure in patients with hiv infection. though renal histological changes were rather non-specific, the existence of a specific, hiv-associated glomerulopathy was postulated. we repeatedly investigated proteinuria and serum creatinine in 203 hiv-infected patients. one hundred and twenty-two patients (group 1) had early stages of the disease without opportunistic infections, 81 s ... | 1992 | 1314985 |
| cytomegalovirus and pneumocystis carinii pneumonia in children with acquired immunodeficiency syndrome. | to ascertain the effect of cytomegalovirus (cmv) infection on the course of pneumocystis carinii pneumonia (pcp) in children with acquired immunodeficiency syndrome (aids), we reviewed the charts of all children with aids who also had a lung biopsy specimen or a bronchoalveolar lavage specimen cultured for cmv at the time pcp was diagnosed. the data indicate that children with aids and pcp whose cultures are positive for cmv do not have a poorer prognosis during a first episode of pcp compared w ... | 1992 | 1317421 |
| disseminated pneumocystis carinii infection in a hemophiliac patient with acquired immunodeficiency syndrome. | a case of disseminated pneumocystis carinii (pc) infection in a 28-year-old japanese male hemophiliac with acquired immunodeficiency syndrome (aids) is reported. the patient had displayed a high fever and diffuse faint interstitial infiltrates on chest x-ray films without dyspnea three months before his death. at that time, no pc was detected after four consecutive induced sputum tests. serum anti-cytomegalovirus (cmv) igm was positive by eia. no treatment for pc and cmv was given at the patient ... | 1992 | 1319101 |
| cytomegalovirus gastritis: protean radiologic features. | infection with cytomegalovirus (cmv) is a major feature of acquired immunodeficiency syndrome (aids). gastrointestinal involvement is being seen more frequently. our collective experience involves nine patients with stomach involvement. seven patients were intravenous drug abusers or homosexuals with aids. one developed cmv gastritis as a complication of leukemia and one patient was a west african with lymphoma and human immunodeficiency virus (hiv) infection. all our patients had biopsy-proven ... | 1992 | 1319363 |
| cdc releases recommendations for prophylaxis against pneumocystis carinii pneumonia. | 1992 | 1320326 | |
| [pulmonary complications in patients with adult t-cell leukemia]. | in order to investigate the character of pulmonary complications in patients with adult t-cell leukemia (atl), a pathological and bacteriological study was performed in 92 autopsy cases with hematologic malignancies including 17 cases of atl and 103 autopsy cases with solid malignancies from 1981 to 1990. among 17 cases with atl, pulmonary complications were seen in 16 cases (94.1%); pulmonary infection in 14 (82.3%), leukemic cell pulmonary infiltration in 9 (52.9%), pulmonary hemorrhage in 5 ( ... | 1992 | 1321303 |
| dual infection with pneumocystis carinii and respiratory viruses complicating bone marrow transplantation. | pneumonia due to dual infection with pneumocystis carinii and respiratory viruses is a rare but formidable complication of bone marrow transplantation. we report here two cases of viral infections complicating p. carinii pneumonia in bone marrow transplant recipients who, at the time of infection, were not taking p. carinii prophylaxis. both patients died following the pneumonia. potential factors contributing to the dual infection included graft-versus-host disease, high-dose steroids and cyclo ... | 1992 | 1324758 |
| subclinical pneumonitis due to pneumocystis carinii in a young adult with elevated antibody titers to epstein-barr virus. | pneumocystis carinii was recovered from the lungs of a 20-year-old woman in apparent good health who had volunteered to undergo bronchoalveolar lavage (bal) as a normal control subject. total and differential cell counts in the bal fluid revealed a significantly increased number and proportion of t lymphocytes, although the cd4:cd8 ratio was in the normal range. despite the lack of specific antibiotic therapy, in a subsequent lavage no p. carinii were recovered, and the total and differential ce ... | 1992 | 1326586 |
| [the respiratory manifestations of the acquired immunodeficiency syndrome in children]. | the authors present the pulmonary complications (infectious and non infectious) in children with aids. it is shown that in this group of children the pulmonary complications are the first cause of death, and among them, the most frequent are the interstitial lymphoid pneumonia and pneumocystis carinii pneumonia. | 1992 | 1327217 |
| pneumocystis carinii pneumonia associated with solid ectopic corticotropin-producing tumors. | 1992 | 1329696 | |
| cytomegalovirus infections in heart transplant recipients: relationship to immunosuppression. | to determine the relationship of cytomegalovirus infections (cmvi) to immunosuppression in heart transplants, we retrospectively compared demographic and clinical variables in 154 consecutive heart transplant patients. forty-one cmvi were compared; of these, 30 (73%) were identified in tissue, and nine (22%) were identified by blood or urine culture. twenty (49%) of the cmvi were self-limited, and 21 (51%) were progressive, requiring treatment. when comparing patients with and without cmvi, demo ... | 1992 | 1329959 |
| [laboratory diagnosis of cytomegalovirus infections and pneumocystis carinii pneumonia in immunosuppressed patients]. | 1992 | 1334217 | |
| [incidence, prevention and therapy of cytomegalovirus and pneumocystis carinii infection after heart transplantation]. | diseases caused by cytomegalovirus (cmv) and pneumonia due to pneumocytis carinii (pcp) are problematic complications after allogeneic heart transplantation. recipients of cmv-seropositive donors have a higher morbidity of cmv. by using an anti-cmv-immunoglobulin preparation in routine prophylaxis the incidence of cmv disease after heart transplantation could be reduced significantly. ganciclovir 10 mg/kg is administered for treatment of cmv disease for at least 14 days. recent investigations sh ... | 1992 | 1334222 |
| [incidence, prevention and therapy of cytomegalovirus and pneumocystis carinii pneumonia after liver transplantation]. | 1992 | 1334223 | |
| aids-defining diseases in 250 hiv-infected patients; a comparative study of clinical and autopsy diagnoses. | to evaluate the correlation between clinical and autopsy findings in 250 aids patients. | 1992 | 1334675 |
| [rapid diagnosis of cytomegalovirus pneumonia and pneumocystis carinii pneumonia by using polymerase chain reaction dna amplification]. | we attempted to detect cytomegalovirus dna (cmv-dna) and pneumocystis carinii dna (carinii-dna) in urine, blood and sputum samples of 16 leukemia patients with pneumonia, using the polymerase chain reaction (pcr). synthetic oligonucleotide primer pair were used to amplify dna from the major immediately genes of cmv and genes for the large subunit of mitochondrial ribosomal rna of p. carinii. amplified products were detected by gel electrophoresis. in two cases, cmv-dna was detected at about the ... | 1992 | 1338207 |
| fungus-specific translation elongation factor 3 gene present in pneumocystis carinii. | historically, pneumocystis carinii pneumonia has been the most frequent cause of morbidity and mortality in patients with aids. antiprotozoan drugs are effective in the treatment and prophylaxis of p. carinii pneumonia, which lends credence to the widely held view that p. carinii is a protozoan. however, recent genetic evidence suggests that p. carinii should be classified as a fungus. translation elongation factor 3 (ef-3) is an essential, soluble translation component which is unique to fungal ... | 1992 | 1339410 |
| [infectious complications of heart-lung transplantation]. | this study describes the infectious complications in 68 heart-lung transplant patients. we focused interest on early post-transplant infections so called nosocomial pulmonary infections, their exacerbating cofactors their clinical expression, and elements of diagnosis and treatment. furthermore we describe the principal infections seen during long-term followup, which are opportunist infections caused most often by immunosuppression: cytomegalovirus infections have a high incidence with serious ... | 1992 | 1340092 |
| detection of pneumocystis carinii in bronchoalveolar lavage fluid by dot immunobinding assay and immunofluorescence. | 1992 | 1341210 | |
| production and characterization of monoclonal antibodies to human pneumocystis carinii for the diagnosis of p. carinii pneumonia. | monoclonal antibodies against human pneumocystis carinii were produced by fusion of myeloma cells (x63-ag8.653) with splenocytes from biozzi mice that had been immunized against p. carinii cysts isolated from infected human lung. the aim of this study was to evaluate the usefulness of these monoclonal antibodies for the diagnosis of p. carinii pneumonia by indirect immunofluorescence in comparison with a modified silver stain method and commercial kits. | 1992 | 1341432 |
| [pneumocystis carinii infection. various aspects on its clinical and laboratory diagnosis]. | p carinii is an opportunistic pathogenic agent able to produce severe infection that must be diagnosed promptly. we analyzed 138 samples from 100 patients suspected of having infection by p carinii. the ortho-toluidine blue and the methenamine stains were used to analyze the samples. infection was demonstrated in 18 patients, 13 adults and 5 children. underlying disease was aids in 7 and other immunosuppressive disorders in the rest. no immunocompetent patient was infected with p carinii. proper ... | 1992 | 1341792 |
| [paracoccidioides brasiliensis (lutz, 1908) isolated by hemoculture in a patient with the acquired immunodeficiency syndrome (aids)]. | a case of an aids patient with positive blood culture for paracoccidiodes brasiliensis is reported. the patient was a 29-years-old male born in nova londrina (paraná state, brazil) who presented splenomegaly and fever of unknown origin. three blood cultures were performed, each one of them for aerobic bacteria, mycobacteria and fungi. cultures for aerobic bacteria and mycobacteria were negative. however, the yeast phase p. brasiliensis was isolated from two cultures in bhi agar, 20 days after in ... | 1992 | 1342126 |
| [japanese clinical statistical data of patients with pneumocystis carinii pneumonia]. | 1992 | 1344377 | |
| [pediatric aids: a report of the first fatal cuban pediatric case]. | the case of a cuban child with aids acquired by perinatal transmission is reported. thirteen days after birth, the child had chronic diarrhoeas affecting its pondostatural development. it was hospitalized many times due to recurrent respiratory processes, in one of which pneumocystis carinii was detected. oral candidiasis, cryptosporidiosis and intestinal amebiasis in faeces were also diagnosed. it died with generalized tonic-clonic convulsions and bradypnea. at autopsy, the direct death cause w ... | 1992 | 1344687 |
| [infections and other opportunistic processes in a group of cuban stage-iv hiv patients]. | forty cuban patients affected by the human immunodeficiency virus (hiv), belonging to group iv, assisted during a year at the pedro kourí tropical medicine institute, are reported. pneumocystis carinii, cryptosporidiosis, mucocutaneous herpes simplex, oral candidiasis and multidermatoma herpes zoster were the most commonly found infections. other non-opportunistic diseases such as dermatitis seborrhoeica and onychomycosis were also present. | 1992 | 1344688 |
| pneumocystis carinii infection complicating cytotoxic therapy in two patients with lymphopenia, but a normal total white cell count. | 1992 | 1346096 | |
| drug interactions in use of dapsone for pneumocystis carinii prophylaxis. | 1992 | 1347616 | |
| seasonal variation in presentation of pneumocystis carinii pneumonia. | 1992 | 1347618 | |
| the effects on survival of early treatment of human immunodeficiency virus infection. | zidovudine has been shown to prolong survival in patients with the acquired immunodeficiency syndrome (aids) and, in persons with human immunodeficiency virus (hiv) infection but not aids, to delay the progression to aids. however, it is still uncertain whether treatment before the development of aids prolongs survival. | 1992 | 1347907 |
| outpatient management of patients infected with human immunodeficiency virus. | the outpatient management of patients infected with human immunodeficiency syndrome is reviewed. patients with cd4+ cell counts of greater than 0.5 x 10(9)/l (500/mm3) require no specific intervention except vaccination against influenza, pneumococcus, and possibly hepatitis b. they should have a follow-up examination every 3 to 6 months. because of its success in preventing the progression of the disease, zidovudine (azt), 100 mg five times per day, is recommended for patients with cd4+ cell co ... | 1992 | 1348266 |
| from the centers for disease control. recommendations for prophylaxis against pneumocystis carinii pneumonia for adults and adolescents infected with hiv. | 1992 | 1348788 | |
| recommendations for prophylaxis against pneumocystis carinii pneumonia for adults and adolescents infected with human immunodeficiency virus. | in 1989, the united states public health service convened a task force of experts to consider the expanding knowledge base about prevention of pneumocystis carinii pneumonia (pcp) among adults and adolescents (greater than or equal to 13 years of age) with human immunodeficiency virus (hiv) infection. this task force concluded that the morbidity, mortality, and cost due to pcp could be substantially reduced by appropriate use of antipneumocystis prophylaxis in subgroups of hiv-infected patients ... | 1992 | 1348843 |
| seasonal incidence of pneumocystis carinii pneumonia. | 1992 | 1349413 | |
| comparison of nebuliser efficiency for aerosolizing pentamidine. | inhaled pentamidine has become an important method of treatment and prophylaxis for pneumocystis carinii pneumonia and we have compared nebuliser efficiency in terms of drug output and droplet sizes in four brands of jet nebuliser (acorn-22, inspiron, cirrus, respirgard ii) and one brand of ultrasonic nebuliser (fisoneb), at 2 pentamidine concentrations and 3 flow rates, using a laser particle sizer. droplet size (which varied from 1.2 to 4.7 microns mass median diameter) was dependent in all ca ... | 1992 | 1350636 |
| prophylaxis for pneumocystis carinii pneumonia in patients infected with human immunodeficiency virus. | following the initial observation by dr. margaret fischl that trimethoprim-sulfamethoxazole can prevent pneumocystis carinii infection in patients with kaposi's sarcoma, initiating prophylaxis for pneumocystic infection in all patients with less than 200 cd4+ cells/mm3 has become accepted practice. this prophylactic intervention has been found not only to reduce the development of pneumonia due to p. carinii but also to prolong life. drs. henry masur and joseph a. kovacs first reviewed prophylax ... | 1992 | 1350925 |
| low-dose trimethoprim-sulfamethoxazole prophylaxis for toxoplasmic encephalitis in patients with aids. | to determine the efficacy of low-dose trimethoprim-sulfamethoxazole (trimethoprim, 160 mg plus sulfamethoxazole, 800 mg; one tablet twice daily, 2 days per week) as primary prophylaxis against toxoplasmic encephalitis in patients with human immunodeficiency virus (hiv) infection and previous pneumocystis carinii pneumonia. | 1992 | 1351371 |
| optimal management strategies for hiv-infected patients who present with cough or dyspnea: a cost-effective analysis. | to determine the effectiveness and costs of alternative management strategies for patients infected with the human immunodeficiency virus (hiv) who present with pulmonary symptoms. | 1992 | 1351940 |
| changes in the spectrum of aids-defining conditions and decrease in cd4+ lymphocyte counts at aids manifestation in germany from 1986 to 1991. | analysis of changes in the spectrum of aids-defining conditions and their correlation with cd4+ lymphocyte counts in different risk groups associated with hiv transmission. | 1992 | 1352106 |