Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| genetic diversity and population structure of eucommia ulmoides oliver, an endangered medicinal plant in china. | eucommia ulmoides oliver, one of the tertiary relict species found only in china, is the only extant species of eucommiaceae. using inter-simple sequence repeat (issr) and sequence-related amplified polymorphism (srap) markers, we studied the genetic diversity and population genetic structure of 187 accessions from 17 e. ulmoides populations throughout its main distribution in china. a total of 65 bands were amplified using eight issr primers, of which 50 bands (76.9%) were polymorphic. meanwhil ... | 2015 | 25867393 |
| suppression of splenic lymphocyte proliferation by eucommia ulmoides and genipin. | we investigated the modulation of innate and adaptive immune cell activation by eucommia ulmoides oliver extract (eue) and its ingredient genipin. as an innate immunity indicator, the phagocytic activity of macrophages was determined by measuring engulfed, fluorescently labeled escherichia coli. as a surrogate marker for the respective activation of cellular and humoral adaptive immunity, concanavalin a (con a) and lipopolysaccharide (lps) induction of primary splenocyte proliferation was assaye ... | 2015 | 25879499 |
| [study on chemical constituents of eucommia ulmoides leaves]. | to investigate the chemical constituents of eucommia ulmoides leaves. | 2014 | 25895383 |
| uplc-ms/ms determination and gender-related pharmacokinetic study of five active ingredients in rat plasma after oral administration of eucommia cortex extract. | eucommiae cortex (ec), the bark of eucommia ulmoides oliv., has been traditionally used to treat many diseases in china for more than 2000 years. the pharmacological effects are primarily attributed to the presence of lignans, iridoids and phenolics, which are main active ingredients in ec. | 2015 | 25910535 |
| a uplc-ms method for simultaneous determination of geniposidic acid, two lignans and phenolics in rat plasma and its application to pharmacokinetic studies of eucommia ulmoides extract in rats. | the bark of eucommia ulmoides is a well-known chinese herbal medicine that is used to regulate blood pressure and reduce blood sugar and fats, as well as an antioxidant and antimicrobial agent. here we describe the development of a sensitive ultrahigh performance liquid chromatography-tandem mass spectrum method for the simultaneous determination of five major active ingredients of e. ulmoides bark extract, namely, geniposidic acid (ga), protocatechuic acid (pca), chlorogenic acid (ca), (+)-pino ... | 2016 | 25990756 |
| neuroprotective effects of eucommia ulmoides oliv. and its bioactive constituent work via ameliorating the ubiquitin-proteasome system. | parkinson's disease (pd) is a chronic neurodegenerative disorder characterized by a loss of dopaminergic neurons in the substantia nigra, decreased striatal dopamine levels, and consequent extrapyramidal motor dysfunction. the purpose of this study was to investigate potential in vivo protective effects of duzhong against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), as well as the bioactive constituents against 1-methyl-4-phenylpyridinium (mpp(+)) toxicity in vitro. | 2015 | 25994206 |
| iridoid constituents from the male flower of eucommia ulmoides and their promotion proliferation on esf-1. | four new iridoids (1, 2, 12, and 13), together with nine known iridoids (3-11), were isolated from the male flowers of eucommia ulmoides oliver and were characterized as 3β-methoxyartselawnin c (1), 6β-hydroxyl-1β,3β-dimethoxyartsclaenin iii (2), 3,4-dihydro-3β-ethoxyasperuloside (12) and 3,4-dihydro-3β-ethoxydesacetylasperuloside (13) by extensive analyses of their 1d and 2d nmr spectroscopy and mass spectra. all of the isolated compounds were assayed for the promoting proliferation of skin fib ... | 2015 | 25996193 |
| herb extracts and collagen hydrolysate improve skin damage resulting from ultraviolet-induced aging in hairless mice. | we examined the effect of the daily ingestion of herb extract from eucommia ulmoides leaves and korean ginseng on skin damage induced by repeated uv irradiation of hairless mice. the herb extract was orally administered to mice at a dose of 1000 mg/kg/day. the hydration of mice dorsal skin decreased significantly with repeated uv irradiation, but did not decrease when the herb extract was administered for seven weeks. transepidermal water loss (tewl) increased with uv irradiation, but decreased ... | 2015 | 26011399 |
| eucommia ulmoides oliv. (du-zhong) lignans inhibit angiotensin ii-stimulated proliferation by affecting p21, p27, and bax expression in rat mesangial cells. | cortex eucommiae (du-zhong) is the dried bark of the eucommia ulmoides oliv. the natural products identified from du-zhong include lignans, iridoids, flavonoids, polysaccharides, terpenes, and proteins, liu et al. (2012). lignans, the main bioactive components, were protective against hypertensive renal injury in spontaneous hypertensive rats in our previous study, li et al. (2012). moreover, eucommia lignans also diminished aldose reductase (ar) overexpression in the kidney, li et al. (2012). h ... | 2015 | 26170892 |
| genetic diversity in intraspecific hybrid populations of eucommia ulmoides oliver evaluated from issr and srap molecular marker analysis. | eucommia ulmoides oliver, the only extant species of eucommiaceae, is a second-category state-protected endangered plant in china. evaluation of genetic diversity among some intraspecific hybrid populations of e. ulmoides oliver is vital for breeding programs and further conservation of this rare species. we studied the genetic diversity of 130 accessions from 13 e. ulmoides intraspecific hybrid populations using inter-simple sequence related (issr) and sequence-related amplified polymorphism (s ... | 2015 | 26214420 |
| microwave-assisted extraction and purification of chlorogenic acid from by-products of eucommia ulmoides oliver and its potential anti-tumor activity. | an efficient method for the rapid extraction, separation and purification of chlorogenic acid (cga) from by-products of eucommia ulmoides oliver (e. ulmoides) by microwave-assisted extraction (mae) coupled with high-speed counter-current chromatography (hsccc) was developed. the optimal mae parameters were evaluated by response surface methodology (rsm), and they were extraction time of 12 min, microwave power of 420 w, ethanol concentration of 75 %, solvent/sample ratio of 30:1 (ml/g), yield of ... | 2015 | 26243912 |
| [study on quality standard of eucommia ulmoides based on absorbed active components in rat plasma]. | the method was established for determination of geniposidic acid, chlorogenic acid, pinoresinoldiglucoside, which are three kinds of constituents of eucommia ulmoides absorbed into the blood components. lc-ms/ms technique was applied to determine the blood components of the bloodstream after administration of e. ulmoides extract. at the same time, hplc was used for detection of the ingredients content of the blood sample from 23 batches of e. ulmoides. the results showed that geniposidic acid, c ... | 2015 | 26323146 |
| simultaneous qualitation and quantitation of natural trans-1,4-polyisoprene from eucommia ulmoides oliver by gel permeation chromatography (gpc). | natural trans-1,4-polyisoprene (tpi) as a functional biomaterial has aroused great interest for rubber industrial product use. here, we proposed a method that enables simultaneous analysis of the content and molecular-weight distribution (mwd) of natural tpi by gel permeation chromatography (gpc). the natural tpis were collected from leaves, fruit coatings and bark of eucommia ulmoides oliver (e. ulmoides) through toluene extraction followed by ethanol purification. the results of tpi contents f ... | 2015 | 26435186 |
| enzymatic hydrolysis and simultaneous extraction for preparation of genipin from bark of eucommia ulmoides after ultrasound, microwave pretreatment. | a continuous process based on the combination of ultrasounds and/or microwaves pretreatments followed by enzymatic hydrolysis and simultaneous extraction (ehse) has been proposed to recover genipin from eucommia ulmoides bark. at first, in the pretreatment step, the mixture of 1.0 g dried bark powder and 10 ml deionized water were irradiated by microwave under 500 w for 10 min. then, in hydrolysis step, the optimal conditions were as follows: 0.5 mg/ml of cellulase concentration, 4.0 ph of enzym ... | 2015 | 26501242 |
| characterization and immunoenhancement activities of eucommia ulmoides polysaccharides. | the aim of this study is to investigate the physicochemical properties, monosaccharide composition and immunomodulatory effects of eucommia ulmoides oliv. polysaccharide. the average molecular weight (mw) of eups was 11.4632 × 10(5)da. the monosaccharide components of eups were glucose, fructose, mannose, fucose, galactose and arabinose with a relative mass of 36.6%, 16.6%, 14.2%, 15.7%, 9.5% and 7.4%, respectively. in in vitro experiments, eups (1.2-75 μg/ml) treatment of dendritic cells (dc) i ... | 2016 | 26572415 |
| vasodilatory effect of wogonin on the rat aorta and its mechanism study. | wogonin, a natural flavonoid, is one of the bioactive compounds of the medicinal herb eucommia ulmoides oliv. widely used in southeastern asia for treating hypertension. however, the molecular mechanisms for the therapeutic benefits remain largely unclear. the present study investigated the vasodilatory effect of wogonin and its possible mechanisms. the flavonoid (0.1-100 µm) caused concentration-dependent relaxations in endothelium-intact aortic rings precontracted with norepinephrine (ne, 1 µm ... | 2015 | 26632179 |
| biosynthesised palladium nanoparticles using eucommia ulmoides bark aqueous extract and their catalytic activity. | palladium nanoparticles (pdnps) are of great importance as catalytic materials. their synthesis has been widely studied and interest in their properties is growing. bio-based methods might be a greener option for designing the pdnps with reduced environmental impacts. this study reports the synthesis of pdnps by utilising the aqueous extract of medicinally important eucommia ulmoides (e. ulmoides) bark which functions as both reducing and capping agent in moderate reaction conditions. reduction ... | 2015 | 26647810 |
| eucommicin a, a β-truxinate lignan from eucommia ulmoides, is a selective inhibitor of cancer stem cells. | cancer stem cells (cscs) constitute a small population of undifferentiated cells within a tumor that have the ability to self-renew and drive tumor formation, thus behaving as cancer-initiating cancer cells. therapeutic interventions that eliminate cscs are necessary to completely cure patients, since cscs are a crucial source of tumor recurrence and metastasis. an induced csc-like (icscl) model was recently established using induced pluripotent stem cells (ipscs). in this study, a natural produ ... | 2016 | 26678322 |
| the restorative effects of eucommia ulmoides oliver leaf extract on vascular function in spontaneously hypertensive rats. | eucommia ulmoides oliv. leaf is a traditional chinese antihypertensive and antidiabetic medicine. we examined the effects of chronic eucommia leaf extract (ele) administration on artery function and morphology in spontaneously hypertensive rats (shrs). ele was orally administered via normal diet ad libitum to six-week-old male shrs at a concentration of 5% for seven weeks. acetylcholine (ach)-induced endothelium-dependent relaxation, sodium nitroprusside (snp)-induced endothelium-independent rel ... | 2015 | 26690110 |
| application of ionic liquids based enzyme-assisted extraction of chlorogenic acid from eucommia ulmoides leaves. | a new approach for ionic liquid based enzyme-assisted extraction (ileae) of chlorogenic acid (cga) from eucommia ulmoides is presented in which enzyme pretreatment was used in ionic liquids aqueous media to enhance extraction yield. for this purpose, the solubility of cga and the activity of cellulase were investigated in eight 1-alkyl-3-methylimidazolium ionic liquids. cellulase in 0.5 m [c6mim]br aqueous solution was found to provide better performance in extraction. the factors of ileae proce ... | 2016 | 26709302 |
| [chemical constituents of eucommia ulmoides in guizhou province]. | to study the chemical constituents of eucommia ulmoides in guizhou province. | 2015 | 26767291 |
| quantitative trait locus analysis of leaf morphological characters, yield-related traits, and secondary metabolite contents in eucommia ulmoides. | eucommia ulmoides is cultivated for the production of eucommia rubber and chinese herbal drugs. molecular breeding methods, such as marker-assisted selection (mas), have the potential to improve the efficiency of e. ulmoides breeding. quantitative trait locus (qtl) analysis was applied to identify marker-trait associations for e. ulmoides using an f1 mapping population of 152 individuals derived from a cross between the wild genotype xiaoye and the cultivar qinzhong no. 1. a total of 78 qtls wer ... | 2015 | 26782433 |
| neuroprotective effect of lignans extracted from eucommia ulmoides oliv. on glaucoma-related neurodegeneration. | glaucoma is a progressive neurodegenerative disease, characterized by retinal ganglion cells (rgcs) and axon degeneration. the development of neuroprotective drug is required for improving the efficiency of glaucoma treatment. eucommia ulmoides oliv. has been used as a source of traditional medicine and as a beneficial health food. lignans is one of the main bioactive components of eucommia ulmoides. here, we show that lignans protects rgcs against oxidative stress-induced injury in vitro. moreo ... | 2016 | 26829935 |
| antidepressant potential of chlorogenic acid-enriched extract from eucommia ulmoides oliver bark with neuron protection and promotion of serotonin release through enhancing synapsin i expression. | eucommia ulmoides oliver (e. ulmoides) is a traditional chinese medicine with many beneficial effects, used as a tonic medicine in china and other countries. chlorogenic acid (cga) is an important compound in e. ulmoides with neuroprotective, cognition improvement and other pharmacological effects. however, it is unknown whether chlorogenic acid-enriched eucommia ulmoides oliver bark has antidepressant potential through neuron protection, serotonin release promotion and penetration of blood-cere ... | 2016 | 26927040 |
| eucommia bark (du-zhong) improves diabetic nephropathy without altering blood glucose in type 1-like diabetic rats. | eucommia bark, eucommia ulmoides oliver barks (du-zhong in mandarin), is an herb used for renal dysfunction in chinese traditional medicine. in an attempt to develop this herb as a treatment for diabetic nephropathy (dn), we investigated the effects of du-zhong on renal dysfunction in type 1-like diabetic rats. | 2016 | 27041999 |
| health-promoting properties of eucommia ulmoides: a review. | eucommia ulmoides (eu) (also known as "du zhong" in chinese language) is a plant containing various kinds of chemical constituents such as lignans, iridoids, phenolics, steroids, flavonoids, and other compounds. these constituents of eu possess various medicinal properties and have been used in chinese traditional medicine (tcm) as a folk drink and functional food for several thousand years. eu has several pharmacological properties such as antioxidant, anti-inflammatory, antiallergic, antimicro ... | 2016 | 27042191 |
| the anti-inflammatory activity of eucommia ulmoides oliv. bark. involves nf-κb suppression and nrf2-dependent ho-1 induction in bv-2 microglial cells. | in the present study, we investigated the anti-inflammatory properties of eucommia ulmoides oliv. bark. (eue) in lipopolysaccharide (lps)-stimulated microglial bv-2 cells and found that eue inhibited lps-mediated up-regulation of pro-inflammatory response factors. in addition, eue inhibited the elevated production of pro-inflammatory cytokines, mediators, and reactive oxygen species (ros) in lps-stimulated bv-2 microglial cells. subsequent mechanistic studies revealed that eue suppressed lps-ind ... | 2016 | 27068259 |
| characterization of glycolytic pathway genes using rna-seq in developing kernels of eucommia ulmoides. | eucommia ulmoides oliver, the only member of the eucommiaceae family, is a rare and valuable tree used to produce a highly valued traditional chinese medicine and contains α-linolenic acid (ala) up to 60% of the total fatty acids in the kernels (embryos). glycolysis provides both cellular energy and the intermediates for other biosynthetic processes. however, nothing was known about the molecular basis of the glycolytic pathway in e. ulmoides kernels. the purposes of this study were to identify ... | 2016 | 27074598 |
| eucommia ulmoides extracts prevent the formation of advanced glycation end products. | proteins non-enzymatically react with reducing sugars to form advanced glycation end-products (ages), resulting in the induction of protein denaturation. because the levels of age increase with age and are elevated in age-related diseases, such as diabetes and atherosclerosis, the intake of compound(s) that inhibit the formation of ages by daily meal may represent a potential strategy for preventing age-related diseases. in this study, we measured the inhibitory effects of several eucommia ulmoi ... | 2016 | 27080730 |
| isolation and characterization of microsatellite markers for eucommia ulmoides (eucommiaceae), an endangered tree, using next-generation sequencing. | eucommia ulmoides oliver, a single extant species of eucommiaceae, is an endemic dioecious tree in china. the natural resources of e. ulmoides have rapidly declined in recent years because of the over-collection of its cortex. to design a suitable protection strategy, it is necessary to develop a set of molecular markers to investigate genetic diversity and population structure of e. ulmoides. pyrosequencing of an enriched microsatellite library by roche 454 flx+ platform was used to isolate sim ... | 2016 | 27173246 |
| [anti-hypertensive effect of total flavonoids of cydonia oblonga leaves and its mechanism based on anti-inflammatory function]. | to study the anti-hypertensive effect of total flavonoids of cydonia oblonga leaves in spontaneously hypertensive rats, then to preliminarily investigate the mechanism of action based on anti-inflammatory function. | 2015 | 27254930 |
| improvement in raw meat texture of cultured eel by feeding of tochu leaf powder. | the muscle of eels fed tochu (eucommia ulmoides oliver) leaf powder was 1.8 times harder than the control. the component analysis showed no difference in moisture, lipid, or protein content between the muscles of the control and the tochu-fed eels. not only the extracted neutral fat but also the compound fat of the raw muscles of the tochu-fed eel and the control had the same tlc patterns and fatty acid composition by gas chromatographic analysis. there was a great difference between the tochu-f ... | 1993 | 27314770 |
| chinese herbal medicines promote hippocampal neuroproliferation, reduce stress hormone levels, inhibit apoptosis, and improve behavior in chronically stressed mice. | an efficacious antidepressant without unwanted side effects is need urgently at present. this study aimed to investigate whether treatment with four chinese herbal medicines (chms), namely radix astragali, saposhnikovia divaricate (sd), eucommia ulmoides oliv. bark (eu), and corydalis yanhusuo w. t. wang (c. yanhusuo), could reverse the effects of chronic mild stress (cms) in a depression-like mouse model and the potential mechanism(s) of their action. | 2016 | 27416803 |
| simultaneous determination of catalpol, aucubin, and geniposidic acid in different developmental stages of rehmannia glutinosa leaves by high performance liquid chromatography. | although r. glutinosa roots are currently the only organ source in clinics, its leaves are a potential supplement for the roots especially in extraction of some important bioactive compounds. our early work found that the contents of catalpol and total iridoid glycosides varied among different developmental stages of r. glutinosa leaves. aucubin and geniposidic acid, the abundant major bioactive compounds in eucommia ulmoides and gardenia jasminoides, respectively, were found present in r. gluti ... | 2016 | 27429834 |
| de novo sequencing of eucommia ulmoides flower bud transcriptomes for identification of genes related to floral development. | eucommia ulmoides oliver is a woody perennial dioecious species native to china and has great economic value. however, little is known about flower bud development in this species. in this study, the transcriptomes of female and male flower buds were sequenced using the illumina platform, a next-generation sequencing technology that provides cost-effective, highly efficient transcriptome profiling. in total, 11,558,188,080 clean reads were assembled into 75,065 unigenes with an average length of ... | 2016 | 27486566 |
| effervescent granules prepared using eucommia ulmoides oliv. and moso bamboo leaves: hypoglycemic activity in hepg2 cells. | eucommia ulmoides oliv. (e. ulmoides oliv.) and moso bamboo (phyllostachys pubescens) leaves are used as folk medicines in central-western china to treat diabetes. to investigate the hypoglycemic activity of the effervescent granules prepared using e. ulmoides oliv. and moso bamboo leaves (ebeg) in hepg2 cells, ebeg were prepared with 5% of each of polysaccharides and chlorogenic acids from moso bamboo and e. ulmoides oliv. leaves, respectively. hepg2 cells cultured in a high-glucose medium were ... | 2016 | 27656239 |
| mechanism and anticancer activity of the metabolites of the endophytic fungi eucommia ulmoides oliv. | pinoresinol (pin) and pinoresinol monoglucoside (pmg) are plant-derived lignan molecules with multiple functions. we showed previously that the endophytic fungus eucommiaulmoides oliverendophytic phomopsis sp. xp-8 is able to produce pin and pmg. cultured xp-8 showed inhibition on hepg-2 and k562 cells and the major effective compounds were identified. the fungal culture significantly inhibited the activities of hepg-2 and k562 cells by decreasing their viability and inducing apoptosis via up-re ... | 2016 | 27671307 |
| extract from eucommia ulmoides oliv. ameliorates arthritis via regulation of inflammation, synoviocyte proliferation and osteoclastogenesis in vitro and in vivo. | eucommia ulmoides oliv., a valuable chinese herb, has shown a variety of health benefits. despite the widespread clinical use of this herb to treat rheumatoid arthritis (ra) in traditional chinese medicine (tcm), very few studies have described its anti-pathological effects or mechanism in ra. the present study investigated the mechanism of eucommia ulmoides oliv. in an experimental collagen-induced arthritis (cia) rat model. | 2016 | 27743778 |
| lignans extracted from eucommia ulmoides oliv. protects against ages-induced retinal endothelial cell injury. | advanced glycation end products (ages) could elicit oxidative stress, trigger and aggravate endothelium damage in several ischemic retinopathies including diabetic retinopathy (dr). the leaves of eucommia ulmoides o., also referred to as tu-chung or du-zhong, have been used for the treatment of hypertension and diabetes, showing great antioxidant activity and anti-glycation activity. lignans is one of the main bioactive components of eucommia ulmoides. this study mainly investigated the effect o ... | 2016 | 27825165 |
| genome-wide identification of micrornas and their targets in the leaves and fruits of eucommia ulmoides using high-throughput sequencing. | micrornas (mirnas), a group of endogenous small non-coding rnas, play important roles in plant growth, development, and stress response processes. eucommia ulmoides oliver (hardy rubber tree) is one of the few woody plants capable of producing trans-1, 4-polyisoprene (tpi), also known as eu-rubber, which has been utilized as an industrial raw material and is extensively cultivated in china. however, the mechanism of tpi biosynthesis has not been identified in e. ulmoides. to characterize small r ... | 2016 | 27877179 |
| megastigmane glycosides from leaves of eucommia ulmoides oliver with ace inhibitory activity. | four new megastigmane glycosides, eucomegastigsides a-d (2, 3, 5 and 7), together with three known megastigmane glycosides, (6r, 7e, 9r)-9-hydroxy-4, 7-megastigmadien-3-one-9-o-[α-l-arabinopyranosyl-(l→6)-β-d-glucopyranoside (1), foliasalacioside b1 (4) and eleganoside a (6), were isolated from the leaves of eucommia ulmoides oliver. their anti-hypertensive effect was investigated in vitro based on the inhibition of angiotensin converting enzyme (ace) using hplc. the results showed that the isol ... | 2017 | 27923676 |
| paenibacillus eucommiae sp. nov., isolated from a traditional chinese medicinal herbal plant eucommia ulmoides oliver. | the taxonomic status of a bacterium designated strain cpcc 100226t isolated from a traditional chinese medicinal herbal plant, e. ulmoides oliver, was characterized by using a polyphasic approach. the aerobic isolate formed pale white colonies on tryptic soy agar (tsa). cells were gram-staining-positive, rod-shaped, motile and endospore-forming. chemotaxonomic investigations revealed the presence of meso-diaminopimelic acid (meso-dap) as the diagnostic diamino acid, mk-7 as the predominant menaq ... | 2016 | 27959785 |
| evaluation of the sedative and hypnotic effects of astragalin isolated from eucommia ulmoides leaves in mice. | the purpose of this study was to evaluate the effects of astragalin on the central nervous system. astragalin is a monomeric compound found in the leaves of eucommia ulmoides using a system solvent method. in the experiments, astragalin showed significant effects on mice, including reduced spontaneous activity, increased sleep ratio, shortened sleep latency and lengthened sleep time with a subthreshold or superthreshold dose of pentobarbital sodium. in addition, astragalin effectively reduced th ... | 2016 | 28013568 |
| preventive effect of eucommia leaf extract on aortic media hypertrophy in wistar-kyoto rats fed a high-fat diet. | eucommia ulmoides oliver leaf extract (ele) has been shown to have anti-hypertensive and anti-obesity effects in rats that are fed a high-fat diet (hfd). to explore the effects of chronic administration of ele on body weight, blood pressure and aortic media thickness, 7-week-old male wistar-kyoto (wky) rats were orally administered a normal diet, a 30% hfd, or a 5% ele plus hfd ad libitum for 10 weeks. the hfd treatment caused mild obesity and hypertension in the normotensive rats, while rats re ... | 2017 | 28100919 |
| effects of simultaneous supplementation of laying hen with α-linolenic acid and eicosapentaenoic acid/ docosahexaenoic acid resources on egg quality and n-3 fatty acid profile. | the aim of this study was to investigate the effects of simultaneous supplementation of laying hen with a-linolenic acid (ala) resources (flax, perilla and eucommia ulmoides seeds) and eicosapentaenoic acid/docosahexaenoic acid (epa/dha) resources (schizochytrium sp.) on egg quality and n-3 polyunsaturated fatty acids (pufa) profile. | 2016 | 28111448 |
| aucubin and its hydrolytic derivative attenuate activation of hepatic stellate cells via modulation of tgf-β stimulation. | eucommia ulmoides is an important traditional chinese medicine and has been used as a tonic with a long history. aucubin is an active component extracted from eucommia ulmoides, which has liver-protection effects. however the mechanisms are still unclear. to investigate the inhibitory effects and the underlying mechanisms of aucubin on tgf-β1-induced activation of hepatic stellate cells and ecm deposition, human hepatic stellate cells (lx-2 cells) were incubated with tgf-β1 to evaluate the anti- ... | 2017 | 28199906 |
| the effects of autohydrolysis pretreatment on the structural characteristics, adsorptive and catalytic properties of the activated carbon prepared from eucommia ulmoides oliver based on a biorefinery process. | eucommia ulmoides oliver (eu) wood was consecutively treated by autohydrolysis pretreatment and chemical carbonization post-treatment based on a biorefinery process. results showed that the optimal condition of the autohydrolysis pretreatment and carbonization process yielded 10.37kg xylooligosaccharides (xos), 1.39kg degraded hemicellulosic products, 17.29kg other degraded products from hemicelluloses and 40.72kg activated carbon (sbet of 1534.06m(2)/g) from the 100kg raw materials. simultaneou ... | 2017 | 28222385 |
| the protective effect of aucubin from eucommia ulmoides against status epilepticus by inducing autophagy and inhibiting necroptosis. | eucommia ulmoides oliv. is a famous traditional chinese medicine which exhibits anti-oxidative stress ability and neuro-protective effects. aucubin is the predominant component of eucommia ulmoides oliv. our present study is intended to investigate aucubin's potential protective effects on neurons against epilepsy in the hippocampus by establishing the lithium-pilocarpine induced status epilepticus (se) rat model in vivo. aucubin (at a low dose and a high dose of 5[formula: see text]mg/kg and 10 ... | 2017 | 28387136 |