Publications

pulmonary edema localized in the right upper lobe accompanying mitral regurgitation.	focal patterns of pulmonary edema are confusing and often mistaken for the more common causes of focal lung disease, pneumonia, infarction, or aspiration. the authors report four cases of right upper lobe edema secondary to mitral regurgitation. the pathogenesis believed to be responsible for this condition is the vector of blood flow from the left ventricle to left atrium, which may be targeted at the right superior pulmonary vein, locally accentuating the forces for edema formation in the righ ...	2009	2704804
studies on oxidized low density lipoproteins. controlled oxidation and a prostaglandin artifact.	low density lipoproteins (ldl), isolated by ultracentrifugal flotation, were oxidized (ldloxid) slowly during dialysis against 0.15 m nacl and subsequent incubation in 96% air-4% co2 at 37 degrees c. butylated hydroxytoluene prevented ldl oxidation. ldl preparations from different sera were oxidized at different rates and the degree of lipid peroxidation was controlled by varying the incubation time. mild oxidation did not alter the electrophoretic mobility of the ldloxid preparations. ldloxid c ...	2009	2715720
identification of gram-positive coccal and coccobacillary vancomycin-resistant bacteria.	a total of 84 of 150 vancomycin-resistant (defined as no inhibition of bacterial growth around a 30-micrograms vancomycin disk placed on 5% sheep blood-trypticase soy agar [bbl microbiology systems, cockeysville, md.]) bacteria were definitively identified by determining the phenotypic criteria. the identity of representatives was also confirmed by dna-dna hybridizations. the following strains were identified: 1 enterococcus faecium, 18 leuconostoc mesenteroides, 15 leuconostoc citreum, 9 leucon ...	1989	2723037
tetrahydroaminoacridine and other allosteric antagonists of hippocampal m1 muscarine receptors.	tetrahydroaminoacridine (tha) and a variety of other nonclassical antagonists of muscarine receptors were studied for their ability to bind to primary and allosteric sites on muscarine receptors in rabbit hippocampal membranes. competition curves between 13 antagonists and 1 nm [3h]pirenzepine (kd = 3 nm) were simple mass action curves, but tha produced steeper curves, indicating positive cooperativity. nonetheless, tha inhibited the binding of low concentrations of [3h]pirenzepine, [3h]n-methyl ...	1989	2725474
childhood obsessive compulsive disorder: a two-year prospective follow-up of a community sample.	a 2-year prospective follow-up of a community-based sample of adolescents previously diagnosed as having obsessive compulsive disorder (ocd) or "obsessive compulsive spectrum" disorder and a control sample was completed by clinicians experienced with ocd but blind to prior diagnosis. an initial diagnosis of ocd or "other psychiatric disorder with oc features" was most likely to predict a diagnosis of ocd at follow-up. subclinical ocd at baseline did not strongly predict continuing psychopatholog ...	2009	2768147
sympathetic uveitis after giant tear repair.	a 33-year-old hispanic man developed sympathetic ophthalmia 4.5 months after vitrectomy and repeat scleral buckling for a giant retinal tear in an aphakic previously traumatized eye. the patient had gray-white, subretinal nodules with characteristic changes of sympathetic uveitis detected by fluorescein angiography. the fluorescein angiographic and clinical findings revealed a dramatic response to steroid treatment: visual acuity returned to the previous 20/20 level within 5 weeks of therapy.	1989	2772419
[single photon emission computed tomography by using n-isopropyl-p-[123i]-iodoamphetamine and 99mtc-hexamethyl propyleneamine oxime in a patient with herpes simplex encephalitis].	single photon emission computed tomographies (spects) by using n-isopropyl-p-[123i-imp]-iodo-amphetamine (123i-imp) and 99mtc-hexamethyl propyleneamine oxime (99mtc-hm-pao) were serially performed in a 70 yrs. old male with herpes simplex encephalitis (hse), and the chronological changes of accumulations were studied. accumulations of both 123i-imp and 99mtc-hm-pao increased initially, and then decreased with the stage of hse being advanced. the sequential appearance of the lesion in hse with 12 ...	2009	2786584
unexpected, unexplained sudden death in young asthmatic subjects.	the clinical course of asthma in four patients younger than 25 years was considered. three died unexpectedly of their disease, and the fourth was successfully resuscitated after cardiopulmonary arrest. none of these patients met the criteria for status asthmaticus in the period preceding their death. the time course of the illness from apparent wellness to death was documented as seconds to minutes. no obvious cause of the severe disease was found at postmortem in two patients or by clinical ana ...	2009	2791673
early clinical results of the ttap acetabular cup.	one hundred seventy-five threaded titanium alloy prostheses (ttap) acetabular cups and 125 cemented cups were evaluated clinically and radiographically at 1 to 3 years postoperatively. the series was statistically different in that there were more women in the cemented group than in the non-cemented group (p less than .001). the cemented group was also older than the threaded group (p less than .001). pain, ambulation, function, range of motion, and roentgenograms were evaluated in all patients. ...	2009	2798250
early clinical results of the ttap acetabular cup.	one hundred seventy-five threaded titanium alloy prostheses (ttap) acetabular cups and 125 cemented cups were evaluated clinically and radiographically at 1 to 3 years postoperatively. the series was statistically different in that there were more women in the cemented group than in the non-cemented group (p less than .001). the cemented group was also older than the threaded group (p less than .001). pain, ambulation, function, range of motion, and roentgenograms were evaluated in all patients. ...	2009	2798250
relationship of serum selenium levels to tumor activity in acute non-lymphocytic leukemia.	serum selenium (se) levels were measured before, during and after high-dose induction chemotherapy in 70 patients with acute non-lymphocytic leukemia (anll). pre-treatment serum se levels were lower in patients than in controls (0.082 +/- 0.033 micrograms/ml versus 0.097 +/- 0.035 micrograms/ml, p less than 0.01). pretreatment serum se correlated inversely with the absolute peripheral blast cell count (r = -0.62, p less than 0.001) and other measurements of the tumor burden. seven days after the ...	2009	2805230
relationship of serum selenium levels to tumor activity in acute non-lymphocytic leukemia.	serum selenium (se) levels were measured before, during and after high-dose induction chemotherapy in 70 patients with acute non-lymphocytic leukemia (anll). pre-treatment serum se levels were lower in patients than in controls (0.082 +/- 0.033 micrograms/ml versus 0.097 +/- 0.035 micrograms/ml, p less than 0.01). pretreatment serum se correlated inversely with the absolute peripheral blast cell count (r = -0.62, p less than 0.001) and other measurements of the tumor burden. seven days after the ...	2009	2805230
an ultrastructural study of pigeon bursa of fabricius during involution.	the ultrastructure of the pigeon bursa of fabricius during involution is described. according to the aa, the involutive process may be divided into 3 stages: an early involutive stage, a late involutive stage and a residual stage. the involutive process starts from epithelium later affecting the follicular medulla and all other structures of the organ. a mucoid degeneration can be observed, followed by an impressive fatty degeneration.	2009	2817414
a morphologic and morphometric study of cells from colloid carcinoma of the breast obtained by fine needle aspiration. distinction from other breast lesions.	morphologic and morphometric studies were carried out on eight cases of pure and mixed colloid carcinoma of the breast initially diagnosed by fine needle aspiration (fna). key morphologic features included (1) cellular smears, (2) single cells, loose aggregates and cohesive groups of cells bathed in a mucinous background, (3) single cells displaying nuclear eccentricity and (4) little variation in nuclear size or shape, with bland-to-accentuated chromatin and rare nucleoli. these morphologic fea ...	2010	2827410
renal failure due to enalapril and captopril in bilateral renal artery stenosis: greater awareness needed.	deterioration in renal function after the use of angiotensin converting-enzyme inhibitors may be the first clue to the presence of bilateral renal arterial stenosis. in order to avoid serious threat to the patient, early detection of the insidious decline in renal function is necessary and depends on routine biochemical monitoring after the initiation of therapy. six cases are described here, to illustrate the very real danger of this class of drugs in this chemical setting; the grave risk of th ...	2010	2835640
opioids and behavior: genetic aspects.	three animal models, based on genetic differences in endogenous opioid peptides and opioid receptors, are described. obese mice and rats, whose pituitary opioid content is elevated, may be used to investigate eating disorders. recombinant inbred strains of mice, which differ in brain opioid receptors and analgesic responsiveness, can be used for study of opioid- and nonopioid-mediated mechanisms of pain inhibition. individual reactivity to opioids can be examined in c57bl/6 and dba/2 inbred stra ...	1988	2837410
molecular cloning of rat phosphoprotein phosphatase 2a beta cdna and increased expressions of phosphatase 2a alpha and 2a beta in rat liver tumors.	a cdna clone coding for an isotype of the catalytic subunit of rat phosphoprotein phosphatase 2a was isolated. the deduced amino acid sequence of the clone was different at 8 positions from that of rat phosphatase 2a alpha determined in a previous study. the deduced amino acid sequence of the clone was, however, identical to that of human phosphatase 2a beta and differed only at one position from that of rabbit 2a beta. thus, the isolated cdna was identified as a clone coding for rat phosphatase ...	1988	2849437
hypotensive effects after topical and intra-arterial administration of alpha-adrenergic agonists in isolated perfused rabbit eyes.	the influence of nonselective and selective alpha-adrenergic agonists on intraocular pressure (iop) was studied in isolated arterially perfused rabbit eyes. drugs were given intra-arterially or topically. with either route of administration, no initial hypertensive phase was observed after l-epinephrine, l-norepinephrine, l-phenylephrine (alpha 1), or methoxamine (alpha 1), but there was an immediate ocular hypotensive effect. the alpha 2-agonist b-ht 920 caused a nonsignificant 1 mm hg fall in ...	1985	2866480
[causes of death and follow-up in life insurance. 5 years' study].		2010	2873492
[adult t-cell leukemia associated with htlv1 and positive hiv2 serology in an african woman].	we report a case of acute adult t-cell leukemia associated with htlv1 infection in a young african woman. the leukemic proliferation consisted of cd4-, cd25-positive lymphoid cells with typically convoluted nuclei and monoclonal integration of the htlv1-proviral dna. the clinical course was characterized by a rapid progression of the leukemia with development of hypercalcemia, resistance to chemotherapy, and the presence of multiple opportunistic infections. the additional finding of a seroposit ...	1988	2898753
comparison of toxic effects of methylguanidine, guanidinosuccinic acid and creatinine in rats with adenine-induced chronic renal failure.	methylguanidine (mg), guanidinosuccinic acid (gsa) and creatinine (cr), which accumulate in the body in parallel with the progress of renal failure after adenine administration, were given separately to rats in order to compare their toxicities. food containing adenine was given to rats for 24 days to induce renal failure, and then each of the test substances was administered intraperitoneally from the following day, the survival rates of the rats being subsequently determined. administration of ...	1989	2918950
berger's disease without iga deposits?		2010	2918964
[changes in the level of endogenous heparin and various indicators of hemostasis in late pregnancy toxemias].		2010	2935011
cellular effects of hematoporphyrin derivative photodynamic therapy on normal and neoplastic rat bladder cells.	hpd is known to localize in neoplastic cells and when exposed to the appropriate wavelength of light causes cytotoxicity. the authors have established a rat urothelial cell model for use in comparing and contrasting the effects of hpd photodynamic therapy (pdt) in normal (rbl-01) and transitional cell carcinoma (ay27) bladder cell lines. uptake, toxicity, and morphologic damage following exposure to hpd pdt were evaluated. trypan blue exclusion was used for determination of the toxicity of sever ...	1986	2936252
fatty acid composition of platelets and of plasma lipid esters in relation to platelet function in patients with ischaemic heart disease.	serum lipoproteins, fatty acids in plasma lipid esters and in platelet phospholipids were assessed in 64 patients with ischaemic heart disease (ihd) and in 67 controls. hyperlipoproteinemia (hlp) (vldl triglycerides greater than 1.4 mmol/l and/or ldl cholesterol greater than 5.2 mmol/l) was found in 64% of the patients. in the plasma lipid esters the relative concentrations of saturated and monounsaturated fatty acids as well as dihomo-gammalinolenic acid were higher in the ihd patients whereas ...	2010	2936356
correction of iatrogenic floating toe following resection of the base of the proximal phalanx.	for many decades, resecting the base of the proximal phalanx was a popular method of correcting hammertoes. the long-term result of the procedure, however, is a flail, proximally retracted, "floating" toe. correction of this challenging surgical problem can be accomplished with a v-y advancement flap and specific releases.	2010	2937523
[provocation tests in coronary artery spasm].		2010	2950442
structural and serological heterogeneity of gamma/delta t cell antigen receptor expression in thymus and peripheral blood.	monoclonal antibodies (mab) reactive against the gamma/delta t cell antigen receptor (tcr) have been used to characterize the distribution and structural properties of gamma/delta tcr-bearing lymphocytes in blood and thymus. consistent with prior reports the tcr gamma/delta-1 and delta-1 mab react with all gamma/delta tcr+ t lymphocytes in blood and thymus. by contrast the tcs-delta mab was found only to react with a subset of the gamma/delta tcr-bearing t cell population. several lines of evide ...	1988	2975598
metabolic zonation in liver of diabetic rats. zonal distribution of phosphoenolpyruvate carboxykinase, pyruvate kinase, glucose-6-phosphatase and succinate dehydrogenase.	the activities and zonal distribution of key enzymes of carbohydrate metabolism were studied in livers of diabetic rats. 48 h after alloxan treatment the following alterations were observed, intermediate values being reached after 24 h: blood glucose, acetoacetate and beta-hydroxybutyrate were increased to more than 500%; liver glycogen was reduced to about 10%. portal vein insulin was reduced to below 10%, portal glucagon was increased to almost 200%. the glucogenic enzymes phosphoenolpyruvate ...	1985	2988584
regulation of the glucose phosphotransferase system in brochothrix thermosphacta by membrane energization.	uptake of 2-deoxyglucose, alpha-methylglucopyranoside, and glucose into intact cells of brochothrix thermosphacta (formerly microbacterium thermosphactum, atcc 11509) was stimulated by kcn or cccp. the glucose analogs were recovered almost totally as the sugar phosphates. membrane vesicles were isolated from protoplasts and shown to be right side out by freeze fracturing and by using atpase as a marker for the cytoplasmic membrane surface. uptake of glucose into vesicles was dependent on the pre ...	1985	2995314
the affinity of (-)-propranolol for beta 1- and beta 2-adrenoceptors of human heart. differential antagonism of the positive inotropic effects and adenylate cyclase stimulation by (-)-noradrenaline and (-)-adrenaline.	an appraisal of the affinity of (-)-propranolol was made for beta-adrenoceptors of isolated heart preparations and myocardial membrane particles from patients undergoing open heart surgery. in order to eliminate possible distorting influences of neuronal and extraneuronal uptakes of catecholamines on the affinity estimates for (-)-propranolol, isolated tissues were pretreated once with 5 or 10 mumol/l phenoxybenzamine for 2 h. phenoxybenzamine caused potentiation of the positive inotropic effect ...	1985	2999616
isolation and buoyant density of pneumocystis carinii in percoll gradients.	a new gradient material, percoll, a collodial suspension of silica particles covered with polyvinylpyrolidon, has been used to isolate pneumocystis carinii from infected rat and human lung tissues. the specific gravity of pneumocystis carinii was shown to be within the range of 1.018-1.062 g/ml with most pneumocysts within 1.033-1.049 g/ml.	1985	3001637
chronic antidepressant treatment reduces central beta-adrenoceptor sensitivity in a behavioural test.	the ability of beta-adrenoceptor agonists to potentiate the head-twitch response to 5-hydroxytryptophan (5-htp) in mice was used to assess the in vivo sensitivity of beta-adrenoceptors 48 h after cessation of acute or chronic administration of desmethylimipramine (dmi) or iprindole (ipd). neither acute nor chronic antidepressant administration significantly altered the head-twitch response to 5-htp alone. forty-eight hours after withdrawal from chronic but not acute pretreatment with dmi or ipd ...	2010	3019728
chronic antidepressant treatment reduces central beta-adrenoceptor sensitivity in a behavioural test.	the ability of beta-adrenoceptor agonists to potentiate the head-twitch response to 5-hydroxytryptophan (5-htp) in mice was used to assess the in vivo sensitivity of beta-adrenoceptors 48 h after cessation of acute or chronic administration of desmethylimipramine (dmi) or iprindole (ipd). neither acute nor chronic antidepressant administration significantly altered the head-twitch response to 5-htp alone. forty-eight hours after withdrawal from chronic but not acute pretreatment with dmi or ipd ...	2010	3019728
on the spin trapping and esr detection of oxygen-derived radicals generated inside cells.	recently several attempts to identify oxygen-derived radicals in whole cells by spin trapping and electron spin resonance have been reported by using 5,5-dimethyl-1-pyrroline-n-oxide as the spin trap. in the present study, the feasibility of this method is examined. chinese hamster v79 cells and human erythrocytes served as the test systems, while oh radicals were generated by gamma radiolysis. several spin traps were used to scavange the radicals and a distinction between exo- and endocellular ...	1986	3020550
on the spin trapping and esr detection of oxygen-derived radicals generated inside cells.	recently several attempts to identify oxygen-derived radicals in whole cells by spin trapping and electron spin resonance have been reported by using 5,5-dimethyl-1-pyrroline-n-oxide as the spin trap. in the present study, the feasibility of this method is examined. chinese hamster v79 cells and human erythrocytes served as the test systems, while oh radicals were generated by gamma radiolysis. several spin traps were used to scavange the radicals and a distinction between exo- and endocellular ...	1986	3020550
regulation of enzymes by ligand induced change in polymerization.		1986	3020906
studies on peptide comodulator transmission. new perspective on the treatment of disorders of the central nervous system.		2011	3024227
mapping of the gene for anti-müllerian hormone to the short arm of human chromosome 19.	the gene coding for human anti-müllerian hormone (amh) was localized to subbands p13.2----p13.3 on chromosome 19, using in situ hybridization and southern blot analysis of a panel of man-mouse and man-hamster somatic cell hybrids.	1987	3028714
structure-activity relationships for steroid interaction with the gamma-aminobutyric acida receptor complex.	certain steroids are potent barbiturate-like modulators of the gamma-aminobutyric acida (gaba) receptor-chloride ionophore complex in rat brain membranes. at nanomolar to low micromolar concentrations, these steroids stimulate [3h]flunitrazepam and [3h] muscimol binding and displace the convulsant [35s]t-butylbicyclophosphorothionate from its binding site in an allosteric manner, in addition to enhancing cl- conductance responses to gaba recorded in cultured rat hippocampal and spinal neurons. a ...	1987	3033209
structure-activity relationships for steroid interaction with the gamma-aminobutyric acida receptor complex.	certain steroids are potent barbiturate-like modulators of the gamma-aminobutyric acida (gaba) receptor-chloride ionophore complex in rat brain membranes. at nanomolar to low micromolar concentrations, these steroids stimulate [3h]flunitrazepam and [3h] muscimol binding and displace the convulsant [35s]t-butylbicyclophosphorothionate from its binding site in an allosteric manner, in addition to enhancing cl- conductance responses to gaba recorded in cultured rat hippocampal and spinal neurons. a ...	1987	3033209
coxsackie b myocarditis.		1987	3040137
the function of superoxide dismutase during the enzymatic formation of the free radical of ribonucleotide reductase.	an enzyme system from escherichia coli activates an inactive form of ribonucleotide reductase by transforming a tyrosine residue of the enzyme into a cationic free radical. the process requires nad(p)h, a flavin, dithiothreitol, and oxygen and at least three proteins. after purification to near homogeneity two of the proteins were identified as superoxide dismutase and nad(p)h:flavin oxidoreductase (fontecave, m., eliasson, r., and reichard, p. (1987) j. biol. chem. 262, 12325-12331). the nature ...	1987	3040738
lipid and lipoprotein effects on endothelial eicosanoid formation.	an important function of endothelium is to release pgi2, a prostaglandin produced from arachidonic acid that prevents platelet aggregation and causes arterial relaxation. small amounts of other eicosanoids also are produced, but their role in endothelial function has not been elucidated. much of the arachidonic acid present in the endothelium is obtained preformed from the plasma, either as ffa or from lipoproteins. arachidonic acid is efficiently incorporated into endothelial lipids even when o ...	2011	3061005
histologic evaluation of response to implantation of polyvinilidine plates in dogs and rats.	the effect of implantation of polyvinilidine spinal plates was studied when placed on spinous processes of 11 mixed breed dogs and when placed within the thoracolumbar musculature of 12 male white rats. specimens were also obtained from soft tissues adjacent to polyvinilidine plates 2 to 3 months after clinical surgery to repair spinal subluxations in three dogs. a similar pattern of dense, organized fibrous tissue interspersed with focal congregations of lymphocytes, plasma cells, and multinucl ...	1988	3067442
dentistry's answer to the "humiliating spectacle".		2011	3076032
glycosaminoglycans in normal and atherosclerotic human coronary arteries.	glycosaminoglycans (gags) were studied in normal and atherosclerotic coronary arteries of 15- to 60-year-old finnish men who had died accidentally. the gags were fractionated and quantified with electrophoretic techniques. the contents of sulfated gags (micrograms/cm2 vessel surface area) increased continuously until 20 to 30% of the vessel surface area was covered with fibrous plaques, after which they started to decrease. the largest increases were seen in chondroitin sulfates a and c and derm ...	1986	3083156
combined modality treatment of cutaneous t cell lymphoma: results of a 6-year follow-up.	thirty-nine patients with cutaneous t cell lymphoma (ctcl; including mycosis fungoides or the sezary syndrome) with no previous treatment other than topical therapy or oral corticosteroids, received total skin electron beam irradiation (tseb) and either sequential or simultaneous systemic chemotherapy. median follow-up, measured from the time of initiation of therapy to the time of analysis, is in excess of 6 years and extends to 100+ months. thirteen patients with stage i disease (limited to sk ...	2011	3088220
[various matters concerning the improvement of therapeutic tactics in epilepsy].	the author has analyzed the results of the therapy of 200 epileptic patients and outlined the main causes of its low effectiveness: a high rate of the development and dissemination of foci of epileptic activity, a limited array of drugs for controlling non convulsive paroxysms of a complex structure, a decrease in the tolerance of large doses of drugs and intercurrent diseases. the author have developed principles of a therapeutic strategy based on the prophylactic treatment in relation to the s ...	2011	3092518
efficacy of danazol in pure red cell aplasia.	twenty-one unselected patients with refractory chronic anemias of various etiologies were treated with danazol, a synthetic attenuated androgen. all had previously failed treatment with hematinics, androgens, corticosteroids, high-dose intravenous immunoglobulin, antithymocyte globulin, cytotoxic immunosuppressive agents, and/or plasmapheresis. three patients with pure red cell aplasia and one with aplastic anemia responded. no responses were observed in 11 patients with myelodysplastic syndrome ...	2010	3098094
cerebral perfusion pressure: a hemodynamic mechanism of mannitol and the postmannitol hemogram.	sixteen patients each received infusions of 1 g of mannitol per kg over 5 to 10 minutes, and serial determinations of intracranial pressure (icp), systemic arterial blood pressure (sabp), central venous pressure, cerebral perfusion pressure (cpp), hematocrit, hemoglobin, serum na+, k+, osmolarity, and fluid balance were carried out for 4 hours. urine output was replaced volume for volume with 5% dextrose in 0.45% nacl solution. we tested the hypothesis that patients with high (greater than or eq ...	2010	3116451
[primary leiomyosarcoma of the pulmonary artery. apropos of a case].	a case of leiomyosarcoma of the pulmonary artery in a 64-year old man without previous cardiovascular disease is reported. the clinical picture, which comprised episodes of paroxysmal dyspnoea associated with acute cor pulmonale, suggested pulmonary embolism. radioisotope perfusion study and pulmonary angiography seemed to confirm this diagnosis, but no improvement was obtained with a prolonged thrombolytic treatment. the presence of a median mass at ct led to exploratory thoracotomy and to the ...	1987	3122693
trimethylaminuria, diagnosed by gas chromatography with nitrogen detection.		2011	3126363
blood storage and transport using a portable thermoelectric refrigerator: field testing.		2011	3126443
follicle-stimulating hormone induces deoxyribonucleic acid polymerase alpha before deoxyribonucleic acid synthesis in immature rat ovarian follicles perfused in vitro.	to examine the effects of follicle-stimulating hormone (fsh) on cell proliferation and cell division in ovaries, deoxyribonucleic acid (dna) polymerase activities and dna concentrations were determined in ovarian follicles of immature, hypophysectomized, estradiol-treated rats perfused in vitro. ovine fsh (2-20 micrograms/ml) significantly enhanced the dna polymerase alpha activity in the follicles perfused for 180-300 minutes, whereas the dna polymerase beta activity and dna concentration showe ...	1988	3126468
antibacterial activity of plantaricin sik-83, a bacteriocin produced by lactobacillus plantarum.	lactobacillus plantarum sik-83 produces a bacteriocin, designated plantaricin sik-83, which inhibits 66 of 68 lactic acid bacteria from the genera lactobacillus, leuconostoc, pediococcus and streptococcus. a 500-fold dilution of l. plantarum sik-83 mrs culture supernatant with phosphate buffer was sufficient to kill 10(5) cells/ml of pediococcus pentosaceus within 120 s. the killing of a sensitive population followed exponential kinetics. it was shown that the bacteriocin binds specifically to s ...	1988	3139056
arachidonate metabolism in immunologic systems.		2011	3144714
local anaesthetic creams.		2010	3145057
local anaesthetic creams.		2010	3145057
an electron microscope study of the development of the exocrine and endocrine pancreas with special reference to intercellular junctions.	intercellular junctions in pancreatic acinar, duct and endocrine cells were studied by thin section and freeze-fracture methods in developing rats and mice. undifferentiated cells were joined by the zonula occludens and isolated fragments of tight junctional strands. small gap junctions were either occasionally associated with tight junctional strands or appeared independent of them. during the morphological differentiation of acinar cells, strands of the zonula occludens developed to form a com ...	1988	3147689
retreatodontics and ultrasonics.		2011	3162934
a comparative study of latamoxef disodium and gentamicin versus piperacillin and gentamicin in febrile granulocytopenic patients.		2011	3179173
scandinavian association of urology. proceedings of the xvith congress. uppsala, may 21-23, 1987.		2011	3187396
[treatment of hypercholesterolemia in adults. an action plan].		2011	3206437
prolonged expression of differentiated phenotype by chondrocytes cultured at low density on a composite substrate of collagen and agarose that restricts cell spreading.	the dedifferentiation of chondrocytes in culture is frequently associated with transition from a rounded to a spread morphology. a number of culture methods which prevent cell spreading have been described; however, all have disadvantages that limit their widespread use. in this paper we describe a new technique which allows prolonged cultivation of attached chondrocytes at low density while inhibiting spreading: the cells are grown on a composite substrate of agarose and collagen. by varying th ...	1988	3209004
fine structure of the a-band in cryo-sections. diversity of m-band structure in chicken breast muscle.	electron micrographs of longitudinal ultrathin cryo-sections and plastic sections of chicken pectoralis muscle together with their average images have been used to study in detail the axial structure of the m-band. it was found that m-band structure could vary markedly in different fibres, even within the white part of the muscle. strong m-band density ("m-bridges") could be seen at m4 and m4' in all fibres. on the other hand the density at m1 or m6 could vary systematically. some fibres (probab ...	1988	3209858
the cell wall structure of a magnesium-dependent halobacterium, halobacterium volcanii cd-2, from the dead sea.	cell wall preparations from the magnesium-dependent halophilic bacterium, halobacterium volcanii, were studied by high-resolution electron microscopy complemented with image analysis and processing. for ultrastructural studies, specimens were prepared by a variety of methods, including negative staining, and metal shadowing after air-drying, freeze-drying, or freeze-fracturing and etching. all methods revealed the cell wall to be composed of a near-hexagonal lattice of unit cells having a center ...	1988	3209861
an illuminated air-fluid switch for vitrectomy.	an illuminated air-fluid switch has been developed to replace the tri-stopcock used for air-fluid exchange during vitrectomy. this system eliminates any confusion that might occur in the darkened operating room during vitrectomy.	2011	3231922
determination of natural penicillins in fermentation media by high-performance liquid chromatography using pre-column derivatisation with 1-hydroxybenzotriazole.		2011	3232829
meningitis-related hearing loss evaluated with evoked potentials.	sixty-seven children with meningitis, ranging in age from 1 month to 14 years, were studied using brainstem auditory evoked potentials. abnormal results were present in 60% of the subjects. serial studies were obtained in 30% of the abnormal patients, 75% of whom demonstrated continued abnormalities on subsequent examination. abnormal studies were found only in those patients who were 6 years of age or younger. the most prominent finding was an increased interwave interval resulting from increas ...	2011	3233104
[clinical case of multiple dental agenesis. orthodontic-prosthodontic resolution].		2012	3255625
functionally polarized layers formed by epidermal cells on a permeable transparent collagen film.	rat epidermal cells were cultured on a transparent collagen film, which was permeable to low mr substances. then the cells were bathed in both media (apical and basal), which were separated by the collagen membrane. the cells formed a multi-layered epidermal sheet with well-developed structures of desmosomes. this sheet on a permeable support was found to be an effective permeability barrier for glucose and amino acids. the epidermal layer showed functional polarity for the uptake and excretion ...	1988	3255753
comparison of 1% sodium tetradecyl sulfate to a thrombogenic sclerosant cocktail for endoscopic sclerotherapy.	this preliminary report suggests superior efficacy of a mixture of sodium tetradecyl sulfate, thrombin and cefazolin (st-thr-cef) over 1% sodium tetradecyl sulfate (st) in the early control of variceal bleeding. the overall management of patients treated with st-thr-cef was superior as indicated by fewer hospital days and lesser transfusion requirements. though trends were suggestive, we were unable to demonstrate a survival advantage for patients treated with st-thr-cef. there was a low number ...	2010	3257666
cancer and interleukin-2.		2011	3260362
cancer and interleukin-2.		2011	3260362
anti-idiotypic antibody used for the localization of parenterally administered monoclonal anti-progesterone antibody in mice.	affinity-purified rabbit and sheep anti-idiotypic antisera raised against mouse monoclonal anti-progesterone igg1 antibody (db3) or mouse myeloma igg1 protein p3 (mopc 21) showed high binding specificities to the respective idiotypes used for immunization as determined by ria or elisa. they have been used in an indirect immunofluorescent method to demonstrate the localization of parenterally administered idiotypes in pregnant or pseudopregnant balb/c mouse frozen tissue preparations, at known st ...	1988	3264081
accentuated formation of the terminal c5b-9 complement complex in patient plasma precedes development of the adult respiratory distress syndrome.	extensive studies have been conducted to determine the pathogenesis of the adult respiratory distress syndrome (ards) by investigating the role of complement, a mediator of inflammation. complement activation products have been detected in blood samples from patients during ards. however, the individual complement components that have been assessed only indicated generalized inflammation, and none could unequivocally discriminate the onset of this acute inflammatory lung injury. in this two-year ...	2012	3264125
supervision of class ii discrepancies.		2012	3272960
[ga-as laser in the treatment of adult periodontitis].		2012	3273004
in human monocytes a strong correlation exists between expression of the m3 antigen, fc-mediated phagocytic activity and failure to participate in extracellular antibody-dependent cytotoxicity.	human fresh blood monocytes can phagocytize and lyse antibody-coated target cells by contact with membrane fc receptors. recently, the monocyte differentiation antigen leu m3 has been described to be associated with monocyte/macrophage maturation pathway and to be linked to functionally distinct monocyte subsets. in the present study peripheral blood monocytes were separated into m3+ and m3- subsets, and evaluated for their ability to mediate antibody-driven effector functions. a clear cut funct ...	1988	3281851
microcomputer basic program to calculate the probability of graft and patient survival in renal transplantation.	a basic program was written for the estimation of the probability of graft and patient survival in renal transplantation on a microcomputer. the program was developed for single-centre statistics in renal transplant units and uses the life table and logrank test method for calculation of survival rates. the program structure is described in detail to make rewriting easy. it is hoped that this report will help transplant centres without access to main-frame computers to develop user-friendly soft ...	2012	3282769
role of host immune system in bb/wor rat. predisposition to diabetes resides in bone marrow.	the role of the immune system in the development of autoimmune diabetes mellitus in the bb/wor rat was studied with bone marrow transplantation methodology. in the first experiment, diabetes-prone (dp) and diabetes-resistant (dr) bb/wor rats were irradiated and reconstituted with bone marrow to create both reciprocal (dp donor----dr host; dr donor----dp host) and syngeneic (dr----dr; dp----dp) histocompatible chimeras. both susceptibility and resistance to subsequent spontaneous diabetes in thes ...	1988	3282942
[treatment of patients with acute surgical diseases associated with diabetes mellitus].		2012	3294492
combination chemotherapy using adriamycin, dtic, cyclophosphamide, and actinomycin d for advanced soft tissue sarcomas: a randomized comparative trial. a phase iii, southwest oncology group study (7613).	the term soft tissue sarcoma refers to a large variety of malignant tumors arising in extraskeletal connective tissues that connect, support, and surround discrete anatomic structures. all visceral organs also contain a connective stroma that can undergo malignant transformation. because of the histological similarities of this group of tumors and their relative rarity, treatment prescriptions for patients that have disseminated disease are most often uniform. in this study, we asked the questio ...	2012	3295129
humoral response in mice immunized with outer membrane proteins of shigella flexneri.	intraperitoneal immunization of mice with outer membrane proteins (omp) of sh. flexneri induced in the animals a synthesis of specific antibodies. their level determined by elisa test was found to be relatively low in the sera of animals immunized with a single dose (10 micrograms) of omp; it was markedly higher in mice immunized with two doses of omp, and very high after three fold immunization. the specific antibodies maintained in the animals for 8-16 weeks after immunization. anti-omp sera g ...	1986	3296993
drug permeability of the endolymphatic sac.	intravenously injected kanamycin sulfate (km) was located in the endolymphatic sac (es) of guinea pigs by an immunohistologic method. kanamycin sulfate had passed through the capillaries in the subepithelial layer and reached the epithelial layer as early as 1 minute after injection. the amount of km in the epithelial layer gradually increased with time (until 30 minutes after injection). the km also accumulated in floating cells in the es. these results tend to indicate that the es is rather ea ...	1987	3304088
[tonometry].		2012	3314683
nitrogenase of klebsiella pneumoniae. kinetic studies on the fe protein involving reduction by sodium dithionite, the binding of mgadp and a conformation change that alters the reactivity of the 4fe-4s centre.	the kinetics of reduction of indigocarmine-dye-oxidized fe protein of nitrogenase from klebsiella pneumoniae (kp2ox) by sodium dithionite in the presence and absence of mgadp were studied by stopped-flow spectrophotometry at 23 degrees c and at ph 7.4. highly co-operative binding of 2mgadp (composite k greater than 4 x 10(10) m-2) to kp2ox induced a rapid conformation change which caused the redox-active 4fe-4s centre to be reduced by so2-.(formed by the predissociation of dithionite ion) with k ...	1987	3318808
an in-vivo model to examine the electromyographic activity of isolated myometrial tissue from pregnant sheep.	strips (2.5 x 3.5 cm) of myometrium alone (myo) or endometrium/myometrium (endo/myo) were removed from the pregnant horn of sheep (day 110 of gestation) and transplanted to sites within the omental fat. these explants developed regular bursts of electromyographic (emg) activity over a period of 7-10 days, as well as a dose-dependent stimulatory response to oxytocin (50-200 mu i.v.). the frequency (per 2 h) of emg bursts in the myo (5.3 +/- 0.2) and endo/myo (5.2 +/- 0.3) explants was significant ...	1988	3339597
growth stimulating activity of lung extract on lung-colonizing colon 26 clones and its partial characterization.	the effects of lung tissue extract on the cell growth of eight colon 26 tumor clones, four highly and four poorly lung-colonizing clones, were examined in vitro. addition of lung extract to serum-free medium stimulated the growth of all four of the highly lung-colonizing clones and one of the poorly lung-colonizing clones, but it had minimal effect on the other three poorly lung-colonizing clones. these results indicate that the lung extract contains a growth stimulating activity; it selectively ...	2012	3345612
a legal framework to eradicate female circumcision.		1988	3386457
a legal framework to eradicate female circumcision.		1988	3386457
cardiopulmonary effects of enprofylline. a xanthine with weak adenosine receptor antagonism in patients with severe chronic lung disease.	the acute cardiovascular effects of a new xanthine, enprofylline, were studied in patients with chronic lung disease. the studies were done during cardiac catheterization (n = 12) and by radionuclide ventriculography (n = 6). enprofylline was given intravenously, 2 mg/kg, and measurements were done after ten and 30 min. enprofylline reduced the mean pulmonary artery pressure from 30 +/- 10 to 26 +/- 7 mm hg (p less than 0.05) and the mean systemic arterial pressure from 92 +/- 17 to 83 +/- 15 mm ...	2010	3396415
agenesis of the gallbladder. a rare cause for a false-positive hepatobiliary image.		2012	3402150
explanation of broca's pupillometer.	broca's pupillometer offers a simple and effective means of measuring the diameter of the pupil. however, it is often used without proper attention to the limitations of its optics. errors of measurement may result from uncorrected refractive error, accommodation, spectacle correction, and spherical aberration (sa). a simple means of minimizing these errors is to hold the pinholes (ph's) of the pupillometer as close to the cornea as is feasible.	2012	3414771
obstetrics '87.		2012	3416253
potentiation of host-mediated antitumor activity by orally administered mushroom (agaricus bispora) fruit bodies.		2012	3416364
hypocitraturia and its role in renal stone disease.		2012	3416412
estrogen receptors in cultured rabbit articular chondrocytes: influence of age.	primary cultures of pubertal and prepubertal rabbit articular cartilage cells were performed. total homogenates or cell extracts were used to determine the specific binding of 17 beta-estradiol. a comparative study was undertaken with tissue minces homogenized without enzymatic treatment. scatchard analysis of cell or tissue extracts revealed the presence of a high-affinity receptor with kd values of 0.55 +/- 0.16 nm and 0.12 +/- 0.03 nm in prepubertal and pubertal rabbit chondrocytes respective ...	1988	3419165
[surgical problems in the treatment of mitral valve insufficiency of ischemic origin].		2012	3436815