Publications

a monoclonal antibody raised to corpus callosum extract reacts with 2',3'-cyclic nucleotide 3'-phosphohydrolase.	monoclonal antibody against 2',3'-cyclic nucleotide 3'-phosphohydrolase (cnp) was generated by fusing mouse myeloma cells with spleen cells from balb/c mice immunized with delipidated white matter from rat corpus callosum. the antibody was characterized by solid-phase radioimmunoassay, immunoblot of sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page), immunoprecipitation from c6 glioma cells, and indirect immunofluorescence staining of monolayer cultures containing oligodendrocy ...	1986	2999339
increased sensitivity of fat cell adenylate cyclase to stimulatory agonists during fasting is not related to impaired inhibitory coupling system.	in rat adipocytes, inhibition of the forskolin-stimulated cyclic amp response by nicotinic acid and n6-phenylisopropyladenosine was unaltered by a 72 h fasting. under assay conditions favouring inhibition, basal and forskolin-stimulated adenylate cyclase responses to inhibition by gtp and nicotinic acid were also unimpaired by fasting. under the same conditions, however, low gtp concentrations elicited a clear activatory effect in membranes from fasted but not from fed rats. fasting failed to al ...	1986	3013688
increased sensitivity of fat cell adenylate cyclase to stimulatory agonists during fasting is not related to impaired inhibitory coupling system.	in rat adipocytes, inhibition of the forskolin-stimulated cyclic amp response by nicotinic acid and n6-phenylisopropyladenosine was unaltered by a 72 h fasting. under assay conditions favouring inhibition, basal and forskolin-stimulated adenylate cyclase responses to inhibition by gtp and nicotinic acid were also unimpaired by fasting. under the same conditions, however, low gtp concentrations elicited a clear activatory effect in membranes from fasted but not from fed rats. fasting failed to al ...	1986	3013688
[hypertrophic pyloric stenosis--an indication for sonography].	the pyloric region of 58 infants who presented with vomiting was examined by real-time ultrasound. transverse diameter of the pylorus and single wall thickness were measured. in 18 patients sonographic diagnosis of hypertrophic pyloric stenosis (hps) was made and subsequently confirmed by surgery. the mean (+/- one standard deviation) of the transverse diameter and of the pyloric wall thickness in patients with hps was 15 (+/- 1) mm. and 5.5 (+/- 0.7) mm., respectively. forty infants matched for ...	2011	3025956
calmodulin-mediated cadmium inhibition of phosphodiesterase activity, in vitro.	ion-stripped bovine brain calmodulin (cam) binds 4 moles cd2+ as well as 4 moles ca2+ per mole protein, with similar affinity; in the presence of 1 mm mg2+ the molar binding ratio of cam for ca2+ decreased to 3, the apparent k0.5 for ca2+ nearly doubled, but the binding characteristics of cam for cd2+ were not changed. saturating concentrations ca2+ did not affect the molar binding ratio of cam for cd2+, but increased the apparent k0.5 for cd2+; vice versa, saturating concentrations cd2+ decreas ...	1987	3034196
[the rooming-in system, everywhere and always?].		2011	3070116
tubulin post-translational modifications and the construction of microtubular organelles in trypanosoma brucei.	we have used specific monoclonal antibodies to facilitate a study of acetylated and tyrosinated alpha-tubulin in the microtubule (mt) arrays in the trypanosoma brucei cell. acetylated alpha-tubulin is not solely located in the stable microtubular arrays but is present even in the ephemeral microtubules of the mitotic spindle. moreover, there is a uniform distribution of this isoform in all arrays. studies of flagella complexes show that acetylation is concomitant with assembly of mts. there is n ...	1988	3075618
nutritional rehabilitation of malnourished patients with cystic fibrosis.	we examined the effect of nutritional rehabilitation in cystic fibrosis patients with severe disease. thirteen malnourished patients (seven males, six females, age 7-27 yr) were studied over 7-16 mo. oral supplementation was attempted initially in 12 patients (mean duration 6.7 mo); only 2 patients gained weight, 2 withdrew, and 1 died. the remaining 7 patients failed to achieve adequate weight gain and were commenced on nasogastric supplementation with a semisynthetic formula. an additional pat ...	2011	3085467
the ability of single sex infections of schistosoma japonicum to induce resistance to reinfection in mice.	in four experiments, mice harbouring an average 50, 76 or over 200 schistosoma japonicum female worms were not resistant when challenged six to eight weeks after infection. the female worms from these single sex infections were stunted and immature (average length 4.6 mm) and induced no overt pathology in the host. male worm burdens of 60, 135 or 140 also induced little or no resistance to challenge in the host. the males from these single sex infections were fully grown for their age (average l ...	1986	3091678
nascent high density lipoproteins from liver perfusates of orotic acid-fed rats.	uniformly fatty livers from orotic acid-fed rats secreted almost no very low density lipoproteins (vldl) but normal amounts of nascent high density lipoproteins (hdl) accumulated in perfusates. when lecithin:cholesterol acyltransferase (lcat) was inhibited, nascent hdl were uniformly discoidal and lacked cholesteryl esters. lipid and apoprotein compositions of nascent hdl from normal and fatty livers were similar whether lcat was inhibited or not. apolipoprotein b-100 was not detected in perfusa ...	1986	3097228
aids publicity: some experiences from scotland.		2010	3101795
aids publicity: some experiences from scotland.		2010	3101795
ampicillin resistant gonorrhoea in hong kong.		1986	3102346
acyclovir update.		2010	3109553
calcium-promoted translocation of protein kinase c to synaptic membranes: relation to the phosphorylation of an endogenous substrate (protein f1) involved in synaptic plasticity.	the translocation of protein kinase c between membrane and cytosol has been implicated in several cellular processes (kraft and anderson, 1983; wooten and wrenn, 1984; akers et al., 1985, 1986; hirota et al., 1985; wolf et al., 1986). we desired to identify potential trigger mechanisms underlying the translocation of protein kinase c activity to neural membranes following the synaptic plasticity observed after long-term potentiation (ltp; akers et al., 1986). takai et al. (1979) have suggested a ...	1987	3121805
hypoperfusion-induced acute renal failure in the rat: an evaluation of oxidant tissue injury.	reactive oxygen species (ros) have been reported to be critical cellular mediators of experimental ischemic acute renal failure (arf). this conclusion is based on observations that in the renal artery occlusion (rao) model of arf, antioxidant drugs confer protection and that renal malondialdehyde (mda) concentrations, an index of lipid peroxidation, rise in the postischemic period. human ischemic arf is most often due to hypoperfusion, not to total blood flow interruption. therefore, the goal of ...	1988	3124972
the laboratory investigation of monoclonal components.		2011	3131211
coamplification of the hst-1 and int-2 genes in human cancers.	the hst-1 gene, previously designated the hst gene, was identified as a transforming gene by transfection assays of genomic dnas from various types of human cancers. we analyzed for alterations of the hst-1 gene in 18 bladder cancers, 23 renal cell carcinomas and 5 esophageal cancers. although rearrangement of the gene was not detected in any of these samples, amplification of the hst-1 gene was found in 4 samples of tumors, including an invasive bladder cancer, both primary esophageal cancer an ...	1988	3133332
[primary arthrodesis of the ankle joint].		2011	3140520
electrophysiologic testing in arrhythmia.		2011	3141437
anti-idiotypic antibodies: a new generation of vaccines against infectious agents.	anti-idiotypic antibodies have been suggested recently as candidates for potential vaccines against numerous infectious organisms. these antibody-based vaccines might represent a new generation of vaccines for inducing protective immunity in susceptible hosts.	2010	3153167
6-mercaptopurine: total body autoradiograms and plasma concentration-time curves of 6mp and metabolites from marmoset monkeys.	to study the body distribution of 6-mercaptopurine (6mp), [8-14c]6mp was given by infusion to 2 marmoset monkeys at a dose rate of 5 mg/kg body weight/h for 1 and 4 h, respectively. both experimental animals were sacrificed 2 h after the end of the drug infusion and instantly frozen at -70 degrees c. whole-body sagittal sections were made later. blood samples were obtained regularly during the experiments to quantitate 6mp, 6mp riboside (6mpr), 6-thioxanthine, and 6-thiouric acid in plasma. the ...	1986	3153226
common acute lymphoblastic leukemia antigen-positive cells in normal bone marrow.		2011	3159444
impaired killer cell generation in the autologous mixed leukocyte reaction by rheumatoid arthritis lymphocytes.	natural killer-like cells are generated along with interleukin-2 (il-2) in the autologous mixed leukocyte reaction (amlr). patients with active rheumatoid arthritis (ra), but not those whose disease is in remission, are poor producers of amlr killer cells. this defect cannot be explained by age, medications, or serum factors. the impaired generation of natural killer-like cells was not influenced by gamma-interferon but could be partially restored by addition of indomethacin to the amlr culture, ...	2011	3160355
aluminum removal: an69-s membrane versus a combined cuprophane and charcoal filter.		2011	3163041
the connecticut hospice, inc. and aids: a profile.		2011	3180805
uptake of br in mitochondria-rich and principal cells of toad skin epithelium.	to elucidate the route of transepithelial cl transport across amphibian skins, electrolyte concentrations and uptake of br in different epithelial cell types of toad skin were determined using electron microprobe analysis. under short-circuited conditions, cl concentrations were about 10 mmol/kg ww lower in mr-cells (23.9 +/- 9.6 mmol/kg ww) than in principal cells and showed a large scatter. after unilateral substitution of br for cl in the bathing solutions, principal cells exchanged br for cl ...	2011	3186433
cases of brain metastasis presenting as the first sign of systemic cancer.		2011	3187577
wisc-r factor structure in a referred pediatric population.	the factor structure of the wisc-r was examined with a large metropolitan pediatric clinic population of referred children. the robustness of the two-factor solution, which parallels the verbal-performance dichotomy, was supported for a group of non-ld children (n = 272) and, with the exception of the coding subtest, for a cohort of ld children (n = 155), as well as with the entire pediatric population (n = 427). kaufman's (1975) three-factor solution was applicable only for the ld cohort. the v ...	2011	3192720
variations in number and functional capacity of blood mononuclear cells during the peripartal period in the gilt.		1988	3195260
the use of colostomy bags for chest tube drainage.	occasionally patients require long-term chest tube drainage. we describe a method whereby a short chest tube may be drained into a colostomy bag to alleviate the necessity of keeping the patient attached to a bulky drainage system. the colostomy bag allows greater mobility, and the patient can be discharged with the bag.	2011	3196108
clinical parameters of donkeys before and after trypanosoma vivax infection.		1988	3201022
the human pattern of gyrification in the cerebral cortex.	the degree of cortical folding found in adult human brains has been analyzed using a gyrification index (gi). this parameter permits the description of a mean value for the whole brain, but also a local specific analysis of different brain regions. correlation analyses of the gi with age, body weight, body length, brain weight and volume of the prosencephalon and the cortex show no significant results. gi values do not differ significantly between male and female brains, right and left hemispher ...	1988	3232854
speech defects as an unusual complication of adenotonsillectomy.		2011	3246230
speech defects as an unusual complication of adenotonsillectomy.		2011	3246230
changes in drinking habits in middle-aged british men.	the drinking behaviour of 7735 middle-aged men drawn from general practices in 24 british towns was determined in 1978-80 and five years later in 1983-85. those with heavier initial drinking were more likely to have reduced consumption after five years. at every level of consumption manual workers showed a greater tendency to decrease drinking than non-manual workers. of those who became non-drinkers over the five years, 12% had been moderate or heavy drinkers. men who were told by a doctor that ...	2012	3256667
[use of allopurinol for the protection of the myocardium from ischemia during aortocoronary bypass].		2012	3266647
forgetting rates in modality memory for young, mid-life, and older women.	a mixed-modality (visual and auditory) continuous recognition task, followed immediately by a final recognition test, was administered to young (18-23 years), mid-life (38-50 years), and older (60-74 years) women. subjects gave recognition responses for both the words and their presentation modality. although older adults remembered less information about input mode than did the two younger groups, the age decrement was not the result of faster forgetting of such information by the elderly. when ...	2011	3267395
forgetting rates in modality memory for young, mid-life, and older women.	a mixed-modality (visual and auditory) continuous recognition task, followed immediately by a final recognition test, was administered to young (18-23 years), mid-life (38-50 years), and older (60-74 years) women. subjects gave recognition responses for both the words and their presentation modality. although older adults remembered less information about input mode than did the two younger groups, the age decrement was not the result of faster forgetting of such information by the elderly. when ...	2011	3267395
an outbreak of cutaneous leishmaniasis.		2011	3271361
structure of 6-(iodomethyl)-2-oxo-2-phenoxy-1,2-oxaphosphorinane.	c11h14io3p, mr = 352.11, monoclinic, p2(1)/n, a = 8.300 (3), b = 14.081 (2), c = 11.326 (4) a, beta = 104.32 (3) degrees, v = 1282.6 (13) a3, z = 4, d chi = 1.823 mg m-3, lambda(mo k alpha) = 0.71073 a, mu = 25.8 cm-1, f(000) = 688, r = 0.035 for 2364 observed reflections. the six-membered ring o(1), p(2), c(3), c(4), c(5), c(6) is in a chair conformation with phenoxy and iodomethyl groups adopting axial and equatorial orientations, respectively. the bond distances and angles are unexceptional.	2011	3271550
prophylactic parenteral antibiotics in clean neurosurgical procedures: a review.	clean surgical procedures carry a risk of postoperative wound infection that is less than 5% in most hospitals. the use of prophylactic antibiotic agents in clean neurosurgical cases is controversial, and the neurosurgical literature through 1980 contains no controlled clinical trials to study its effectiveness in such cases. a report of 1732 consecutive procedures without a single postoperative wound infection in patients receiving systemic gentamicin, vancomycin, and streptomycin irrigation fl ...	1988	3288725
the effect of resilient layer and occlusal reactive complete dentures on the residual alveolar ridge.	a technique for making resilient layer and occlusal reactive dentures was proposed. a radiographic and clinical evaluation of the effect of these dentures on the residual ridges of 17 subjects was done. the results showed that the rate of ridge reduction with these dentures was significantly less than that with conventional dentures. therefore, the resilient layer principle is a promising clinical modality.	2009	3290456
behavior of beta 2-microglobulin in patients with chronic renal failure undergoing hemodialysis, hemodiafiltration and continuous ambulatory peritoneal dialysis (capd).	beta 2-microglobulin (beta 2-m) is the major component of a new form of amyloid deposit found in carpal tunnel syndrome and dialysis arthropathy of long-term hemodialysis patients. in 52 patients on maintenance hemodialysis, serum beta 2-m concentration was elevated to 37.9 +/- 1.4 (normal 1.2 +/- 0.6) mg/l. it was correlated with the time on hemodialysis (r = 0.43, p less than 0.01) and was inversely correlated with residual renal function (r = 0.87, p less than 0.001). in 20 patients on capd, ...	2012	3297439
[prof. hugon kowarzyk].		2012	3299332
[subcutaneous rupture of tendons and muscles of the extremities].	under study there were 278 patients with 285 subcutaneous ruptures of tendons and muscles of the upper and lower extremities. the tendon of the long head of the humeral biceps muscle and achilles tendon are most liable to subcutaneous ruptures (123 patients--43.2% and 97 patients--34% respectively). pathohistological examinations have shown that subcutaneous ruptures of tendons and muscles usually take place against the background of dystrophic alterations reducing their mechanical strength. the ...	2012	3303625
[spasmophilia: a new interpretation of psychogenic reactions in dental studies?].		2012	3323870
does it matter how we feed premature babies?	the multiplicity of dietary regimes available for low birthweight infants is a measure of clinical uncertainty in this field. the reasons for this persisting uncertainty are analysed: few studies have examined whether early diet matters in terms of clinical outcome; instead, management decisions have been based on short-term 'physiological' studies on nutrient accretion, growth and metabolism. data from this unit's multicentre outcome trials on nearly 1000 preterm infants, randomly assigned to e ...	2012	3328120
sublethal exposure to microwave radar.		2011	3336157
sublethal exposure to microwave radar.		2011	3336157
laboratory use: persisting attitudes implicit in a national examination.		2012	3337509
psychoneurogenic stress influences upon retention of an inhibitory avoidance response in the rat.	hormones and peptides involved in the response of an organism to stress play a modulating role in learning and memory processes. we studied whether psychoneurogenic stressors such as sound stimulation or novelty influence retention of an inhibitory avoidance response. an impairing effect on retention was observed when these stressors were applied shortly after the acquisition trial, but not after a 3-h delay. however, sound stimulation and novelty applied shortly before the retention test may fa ...	1988	3345185
therapeutic advisory program: an opportunity for clinical pharmacology.		2012	3345613
nasal mucosal blood flow after intranasal allergen challenge.	the nasal mucosal blood flow in patients with allergic rhinitis was determined at nasal allergen challenges with the 133xenon washout method. determinations were made in 12 subjects before and 15 minutes after challenge with diluent and increasing doses of allergen. the time course was followed in eight subjects by means of repeated measurements during 1 hour after a single allergen dose. finally, the blood flow was measured after unilateral allergen challenge in the contralateral nasal cavity. ...	2012	3346485
bioprostheses in tricuspid and mitral valve positions for 100 months with heavier calcific deposits on the left-sided valve followed by new bioprostheses in both positions for 95 months with heavier calcific deposits on the right-sided valve.		2012	3354478
[percutaneous treatment of pulmonary arteriovenous aneurysms disclosed by cerebral abscesses. apropos of 2 new cases].		2012	3369817
structural organization of the mouse mitochondrial malate dehydrogenase gene.	structural organization of the mouse mitochondrial malate dehydrogenase (ec 1.1.1.37) gene was determined by analyzing a genomic dna fragment isolated from a cosmid library. the gene is 12,000 base-pairs long and contains nine exons interrupted by eight introns of various sizes. the 5' and 3'-flanking regions, and the exact sizes and boundaries of the exon blocks including the transcription-initiation sites were determined. in the 5'-flanking region, there is neither a tata box nor a caat box. i ...	1988	3379635
[patients with multiple trauma with involvement of the extremities and/or the pelvis].		2012	3387798
variations in resting metabolic rates of men in antarctica.	the resting metabolic rates (rmr) of 6 men was determined monthly for 12 consecutive months, at rothera base, antarctica (67 degrees 34's, 68 degrees 07'w). body weight and body composition were also recorded. metabolic rates were within the range of those found in past polar studies, and of young men in the uk, but varied considerably from month to month. the rmr had a mean range of 30% (p less than 0.01), with individual ranges of up to 38%. mean rmr was high in spring, summer and autumn, and ...	2012	3396566
a technique for simulating the amplifier-to-eardrum transfer function of an in situ hearing aid.	there are numerous articles wherein mathematical models of various parts of an in situ hearing aid have been reported. such parts include, for example, the microphone, receiver, cylindrical tubes carrying sound to the eardrum and out through the earmold vent, and the external path from the vent back to the microphone. this article extends these earlier works to include the hearing-aid amplifier. in particular, a mathematical technique for characterizing the amplifier in combination with the rece ...	2012	3411037
biodegradable microspheres. x: some properties of polyacryl starch microparticles prepared from acrylic acid-esterified starch.	acrylic acid-esterified starch was produced by reacting starch with acrylic acid chloride. this reaction was rapid and easy to control. introduction of acrylic groups into starch reduced the enzymatic degradability of starch (e.g., with 12 acrylic groups/100 glucose residues, approximately 75% of the degradation products eluted before glucose on gel filtration). the degradability could be increased to a large extent by preincubation at ph 5.5 in vitro (e.g., after 16 weeks, the corresponding fig ...	2012	3440940
imbalance in the ribonucleotide pools of lymphoid cells from acute lymphoblastic leukemia patients.	the intracellular purine and pyrimidine ribonucleotide concentrations were determined in the lymphoid cells from peripheral blood and/or bone-marrow of 29 patients with acute lymphoblastic leukemia (all), as well as in the mononuclear cells from peripheral blood of 12 patients with all in remission. the lymphoid cells of all patients showed an imbalance in the nucleotide pool compared with normal lymphocytes, whereas the nucleotide pool of mononuclear cells from patients with all in remission ha ...	2012	3457224
chronopharmacological study of furosemide in rats.	the present experiment was undertaken to determine whether or not the effects of furosemide depend upon the administration time and, if so, to study the mechanism(s) for these variations. after administration of furosemide (5 mg/kg) in wistar rats at 10:00 or at 22:00, urine volume and urinary excretion of sodium, furosemide, and prostaglandin e2 (pge2) were measured. urine volume and urinary excretion of sodium and furosemide, but not pge2, were significantly greater when furosemide was adminis ...	1986	3457231
[quantitative analysis of dental wear and its correlation with the morphology and pathology of condylar wear].		2012	3476826
peripheral blood natural killer cell activity in human breast cancer patients and its modulation by t-cell growth factor and autologous plasma.	the role of clinical status and chemotherapeutic intervention on native and inducible natural killer cell (nk) activity in breast cancer was ascertained by determining the k562 cytotoxicity capacity of peripheral blood lymphocytes. the level of nk activity in breast cancer patients receiving chemotherapy (n = 62) was significantly lower than that observed in patients currently receiving no treatment (n = 56) (at effector: target [e:t] ratios of 20:1, 10:1, and 5:1, 23.8%, 17.9%, and 12.1% versus ...	1986	3487379
[ferric sulfate in minor oral surgery].		2012	3488235
separation of the genetic loci for the h-y antigen and for testis determination on human y chromosome.	the mammalian y chromosome encodes a testis-determining factor (termed tdf in the human), a master regulator of sex differentiation. embryos with a y chromosome develop testes and become males whereas embryos lacking a y chromosome develop ovaries and become females. expression of h-y, a minor histocompatibility antigen, may also be controlled by a gene on the y chromosome, and it has been proposed that this antigen is the testis-determining factor. we have tested the postulated identity of h-y ...	1987	3494951
[analysis of factors related to early mortality in digestive hemorrhage caused by portal hypertension].	in order to determine immediate criteria of prognosis for patients with portal hypertension hospitalized for digestive hemorrhage, in an intensive care unit, 18 variables were recorded during the 24 hours following admission in 65 patients. data related to death were age, ascites, hepatic encephalopathy, shock, active hemorrhage, acute pneumonia, decrease in prothrombin time, use of esophageal balloon tamponade, use of mechanical ventilation, number of red blood cell units transfused. discrimina ...	2012	3497065
[clinical results of a combined peri- and intra-venous technic in endoscopic sclerosis of esophageal varices].	a series of 20 patients with bleeding oesophageal varices treated by endoscopic sclerotherapy is presented. the technique employed involved injecting the sclerosing fluid into peri- and endovenous variceal sites once a week for 4 weeks running followed by a month's rest. up to three of those cycles were performed. however in 12 patients the risk of bleeding had fallen from 100% to 0% after 6 sessions. in the other 6 patients the risk was eliminated after the remaining cycles. in 2 patients only ...	2012	3498915
the marihuana perception inventory: stage 1--development.		2012	3501461
analysis of the internal nuclear matrix. oligomers of a 38 kd nucleolar polypeptide stabilized by disulfide bonds.	when rat liver nuclei are treated with the sulfhydryl cross-linking reagent sodium tetrathionate (natt) prior to nuclease treatment and extraction with 1.6 m nacl, residual nucleoli and an extensive non-chromatin intranuclear network remain associated with the nuclear envelope. subsequent treatment of this structure with 1 m nacl containing 20 mm dithiothreitol (dtt) solubilizes the intranuclear material, while the nuclear envelope remains structurally intact. we have isolated and partially char ...	1986	3514251
intravenous digital subtraction angiography in the diagnosis and management of acute aortic dissection.	eleven patients presenting with the clinical diagnosis of suspected aortic dissection underwent intravenous digital subtraction aortography. in nine patients digital subtraction angiography (dsa) was performed as the investigation of first choice. in five of these the diagnosis was confirmed with this technique alone and surgical repair was undertaken without further investigation. direct cine aortography was also undertaken in the other four patients and confirmed the dsa findings, demonstratin ...	2012	3552681
[phrenic paralysis after heart surgery with extracorporeal circulation. apropos of 34 cases].		2013	3566145
spectrophotometric determination of tungstate using an iron salt, a thiol and oxygen.		2013	3592240
varied appearance of cardiac pseudoaneurysms on blood pool images.	three cases of cardiac pseudoaneurysms were presented, with findings at the time of gated blood pool imaging. in only one of three was there the finding of a small neck connecting the ventricular cavity with the pseudoaneurysm. in the other two patients, there was a considerably larger communication. the size of the pseudoaneurysm itself was also of little diagnostic assistance. in one case it was small, while in a second patient it was larger in size. the third case revealed a pseudoaneurysm of ...	2013	3595025
effect of altrenogest and lutalyse on parturition control, plasma progesterone, unconjugated estrogen and 13,14-dihydro-15-keto-prostaglandin f2 alpha in sows.	to investigate control of parturition time, 154 sows farrowing 220 litters at three locations were treated with altrenogest and lutalyse (pg). the four treatment groups were: 1) no treatment (control group); 2) an im injection of 15 mg of pg at 1000 on d 111, 112 or 113 of gestation (d 0 = first day of estrus and gestation); 3) altrenogest (20 mg x sow-1 x d-1) fed twice daily for 4 d starting on d 109, 110 or 111; and 4) altrenogest and an injection of pg at 1000 on the day after the last feedi ...	1987	3610870
[data providing a basis for the mac of the cleaning agent "blesk-3" in work zone air].		1987	3623181
a patient with miliary tuberculosis and acute adrenal failure.		2011	3627308
[computer rejection--computer euphoria: how sane is the world of computers?].		2013	3640913
[asphyxia in newborn infants--zinc treatment during pregnancy. 1-year study in söderhamm's health district].		2012	3641832
validating the learning disabled adult: a response to lieberman.		2012	3655545
validating the learning disabled adult: a response to lieberman.		2012	3655545
[argon laser treatment of capillary hemangioma (nevus flammeus)].		2013	3660375
a scanning electron microscope study on the autonomic groundplexus in the lamina propria mucosae of the guinea-pig small intestine.	the occurrence and fine structure of the autonomic groundplexus in the lamina propria mucosae of the guinea-pig small intestine were studied by scanning electron microscopy after removing connective tissue elements by maceration in hydrochloric acid. transmission electron microscopy was also performed to investigate the fine structure of the neuronal and glial elements in the autonomic groundplexus. nerve fasciculi consisting of neuronal processes and enteroglial cell sheaths formed a three-dime ...	1987	3662754
covalent binding of an nad+ analogue to horse liver alcohol dehydrogenase in a ternary complex with pyrazole.	examination of the model of the fixation site of the adenosine phosphate part of nad+ on horse liver alcohol dehydrogenase led us to synthesize a nad+ analogue n6-[n-(8-amino-3,6-dioxaoctyl)carbamoylmethyl]-nad+ in order to alkylate the carboxylic acid group of asp-273 and to convert the normally dissociable coenzyme into a permanently bound prosthetic group. this nad+ analogue is coupled to the horse liver alcohol dehydrogenase in the ternary complex formed with pyrazole. in these conditions th ...	1987	3665930
dissociation and reassociation of trichocyst proteins: biochemical and ultrastructural studies.	trichocysts, the crystalline exocytotic organelles in paramecium tetraurelia, are composed of small, acidic proteins existing primarily as disulphide-linked dimers. we have disaggregated trichocyst proteins with heat, simultaneously observing the changes in morphology and protein composition. the tip matrix was most heat-labile; its subunits progressively broke away from the distal end. during this process, breakdown of the cylindrical shaft began. shafts first became flattened and torn lengthwi ...	2013	3667715
distribution of immunoreactive inhibin like material in different regions of human prostate.	distribution of immunoreactive inhibin material (ir-ilm) in different regions of human prostate was studied by using specific radio-immunoassay. mean ir-ilm concentrations in the central, peripheral and periurethral zones were 27.3 +/- 9.3, 2.4 +/- 0.7 and 3.0 +/- 1.5 micrograms/mg protein respectively (p central vs periurethral and peripheral less than 0.05).	1987	3688474
craniofacial osteotomies to facilitate skull base tumour resection.	in order to expose deeply situated tumours of the skull base in various regions, the concept of osteotomies of segments of the facial skeleton has been developed. the portion of skeleton overlying the tumour is removed, the lesion is resected and the removed bony structure is then reinserted. this has greatly facilitated tumour removal in difficult areas. the advantages of this approach are, to the surgeon, total en bloc resection of deeply situated tumours with few complications; for the patien ...	2013	3697557
pharmacokinetics of meperidine in spinal anaesthesia.	five male patients undergoing haemorrhoidectomy received intrathecal meperidine 1 mg x kg-1 as the sole anaesthetic agent. plasma concentration-time profiles were investigated. the peak plasma concentration of meperidine was 175 +/- 78.8 ng x ml-1 (mean +/- sd) and this occurred 90 minutes after intrathecal injection. the plasma concentrations generally were lower than those necessary for systemic analgesic effects. the terminal elimination half life of meperidine (t 1/2 beta) in the plasma was ...	2012	3697812
qsar in a series of muscarinic agents. note vi. five-membered cyclic ligands.	proceeding in our study on the muscarinic receptor site, a refinement of its topology by means of quantitative structure-activity relationships has been carried out. specific key structures have been selected considering not only muscarine and the corresponding desether derivative, but also a set of cyclopentenyltrimethylammoniummethyl salts. these derivatives, considered in a correlation equation extended to all of the five-membered cyclic structures previously examined, significantly improve u ...	2013	3720943
relationship of duodenal ulcer with diet, smoking, family history and blood group.		2013	3741299
high oxygen requirements of dyskinetic cardiac muscle.	this study assesses the regional oxygen requirements of muscle segments that are beating and working, beating and empty, arrested and decompressed, and nonischemic that move dyskinetically. regional oxygen demands were evaluated by producing a dyskinetic segment by infusing regional cardioplegic solution through a left anterior descending coronary artery catheter with and without extracorporeal circulation. the results show that the o2 demands of the perfused dyskinetic cardiac muscle segment (4 ...	1986	3747582
in vitro acetylcholine synthesis and oxidative metabolism during development of normal and brindled mouse brain.	during early development normal and brindled mouse brain use 3-hydroxy-butyrate preferentially to glucose as a source for biosynthetic carbon units. on postnatal days 5-60, co2 and acetylcholine production from 3-hydroxybutyrate decrease while that from glucose increases. glucose metabolism exceeds that of 3-hydroxybutyrate after weaning (day 21). these findings indicate that the immature brain uses 3-hydroxybutyrate to support effectively oxidative metabolism and acetylcholine synthesis. defici ...	1986	3768723
the effect of altered hormonal states on some enzymes of gluconeogenesis in the genital organs of immature female rhesus monkeys.		1986	3779756
[left ventricular function after surgical closure of ventricular septal defects--comparison of results one year and three years after surgery].		2013	3794426
coronary hemodynamics and myocardial metabolism of lactate, free fatty acids, glucose, and ketones in patients with septic shock.	to investigate disturbances in the coronary circulation and myocardial metabolism during septic shock, we examined coronary sinus blood flow and myocardial substrate extraction in 40 patients with septic shock and 13 control patients. patients with coronary artery disease were excluded from this study. the global hemodynamic pattern of the septic patients was characterized by a lower stroke volume, despite an elevated cardiac index. coronary sinus blood flow was high (187 +/- 47 vs 130 +/- 21 ml ...	1987	3815765
unrecognized myocardial infarction: experience in the multiple risk factor intervention trial (mrfit).		2011	3815790
[fatigue in adolescents].		2013	3834853
sensitivity of anti-leu-m1 as a marker in hodgkin's disease.	seventy-eight cases of hodgkin's disease (52 nodular sclerosis, 13 mixed cellularity, seven lymphocyte predominance, one lymphocyte depletion, one interfollicular, and four unclassified cases) were stained with anti-leu-m1 using the immunoperoxidase technique on either formalin- or b-5-fixed, paraffin-embedded sections. the cytoplasmic pattern and extent of staining of reed-sternberg cells and mononuclear variants were recorded. ninety-four percent of the cases had leu-m1-positive cells. the sta ...	2013	3840354
animal cell mutants defective in glycosaminoglycan biosynthesis.	we have obtained chinese hamster ovary cell mutants defective in the biosynthesis of glycosaminoglycans by screening replicate colonies immobilized on polyester cloth. depending upon the strain, the mutants accumulated less 35s-labeled glycosaminoglycans per microgram of cell protein by a factor of 6-60 compared to the wild type. some of the mutants incorporated [6-3h]glucosamine into glycosaminoglycans to the same extent as the wild type, suggesting that sulfate addition was specifically altere ...	2013	3858816