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tolerance of mefloquine alone and in combination with sulfadoxine-pyrimethamine in the prophylaxis of malaria.a randomized double blind study was performed to evaluate the tolerance and the acceptance of mefloquine alone (lariam) compared to a combined drug regimen consisting of mefloquine, sulfadoxine and pyrimethamine (msp; fansimef) in the prophylaxis of malaria. 175 europeans travelling to different malaria endemic areas received either mefloquine alone (250 mg/week) or its combination with sulfadoxine (500 mg/week) plus pyrimethamine (25 mg/week). one person taking mefloquine and two taking msp dis ...19892694482
current management of salivary gland tumors. part 2.the authors base their treatment of salivary gland malignancies on the size of the primary and the histopathologic diagnosis. group 1 includes smaller tumors in the t1 and t2 classification with cell types that are associated with slow growth. a parotidectomy is usually sufficient therapy for tumors in this group. group 2 contains t1 and 2 tumors with more aggressive behavior. total parotidectomy is indicated here, with postoperative radiotherapy. t3 tumors and patients with nodal metastasis or ...19892701414
triglyceride and cholesteryl ester hydrolysis in a cell culture model of smooth muscle foam cells.cultured rabbit aortic smooth muscle cells were converted to foam cells by exposure to sonicated lipid droplets of defined composition using an inverted culture technique. uptake of the lipid droplets by the cells was shown to be dependent on the time of exposure to the droplets and on the mass of droplets presented to the cells. a comparison of the hydrolysis of triolein and cholesteryl oleate by cells that had been exposed to isotropic lipid droplets containing equimolar amounts of the two lip ...19892715724
[fibrinogen and pentoxifylline. results of a french cooperative exploratory study of stage ii arteritis].a collaborative exploratory study was undertaken by 139 private angiologists in 427 out-patients with pvd stage ii treated for 90 days with pentoxifylline 1 200 mg per day. in 306 patients (71,6%) the fibrinogen level was decreased by 0,21 g/l in mean (p less than 0.01). this significant decrease is correlated to the global improvement (p less than 0.01) and is within the magnitude of difference that is associated between vascular death and comparative groups in recent epidemiologic studies. in ...20092715734
a role for dna characterisation in ovine footrot.bacteroides nodosus involved in several outbreaks of ovine footrot over a number of years were subjected to dna restriction endonuclease analysis. individual isolates were found to have characteristic bam hi profiles which permitted their accurate identification and differentiation from other isolates. bam hi profiles of b. nodosus isolates were used in epidemiological investigations involving consecutive outbreaks of footrot on individual and neighbouring farms. the relationship of given isolat ...19892730474
evaluation of techniques for recognition of ventricular arrhythmias by implanted devices.implantable devices that provide antitachycardia and defibrillation capability currently have limited ability to distinguish among different cardiac rhythms. we have investigated three methods of electrogram analysis: rate, irregularity, and amplitude distribution. in 35 episodes in 19 patients, we applied these three algorithms to 15 s recorded passages of ventricular electrograms during supraventricular tachycardia (n = 11), ventricular tachycardia (n = 11), and ventricular fibrillation (n = 1 ...20092731947
effectiveness of vaccination in controlling ovine footrot.efficacy of reducing footrot by use of a commercial vaccine was evaluated over 2 yr with 223 ewes from five crossbred genotypes. ewes were assigned randomly within genotype, age and initial footrot status to a 2 x 3 factorial array of vaccination in the 1st yr and fall vaccination, winter vaccination or control in the 2nd yr. the flock contained a single bacteroides nodosus serotype (xv) known to be highly cross-reactive with one of the vaccine serotypes (british serotype h). vaccination reduced ...19892737976
time-resolved extrinsic fluorescence of aromatic-l-amino-acid decarboxylase.the coenzyme-linked fluorescence of aromatic-l-amino-acid decarboxylase decays non-exponentially. the decay of both native and nabh4 reduced samples can only be fitted by two exponentials each roughly accounting for about half of the total fluorescence. denaturation of the reduced protein with 8 m urea makes the fluorescence decay mono-exponential, like that observed for the reference compound pyridoxamine-5-phosphate. an extra pyridoxyl moiety can be bound to the enzyme after incubation with ex ...19892752045
efficacy of a multivalent bacteroides nodosus vaccine against foot rot in sheep in britain.a multivalent bacteroides nodosus foot rot vaccine was tested by comparing the prevalence of foot rot in 317 vaccinated ewes and lambs with the prevalence in 422 unvaccinated control sheep. the vaccine conferred statistically significant protection against foot rot. the vaccine also demonstrated a therapeutic effect in animals with foot rot, after one injection.19892773254
a positive association between resistance to ovine footrot and particular lymphocyte antigen types.the distribution of 12 class i ovine lymphocyte antigens (ola) was examined in 4 flocks of sheep vaccinated against and/or challenged with bacteroides nodosus, the transmitting agent of footrot. in a flock of 47 corriedales in new zealand, which had been specially bred for resistance to footrot, a higher frequency (70.2%) of ola type sy6 was found compared with 42.9% in 49 unselected corriedale sheep (p = 0.001). the serum antibody response of 12 selected corriedale ewes was compared with that o ...19892775053
platelet aggregation induced by type iib platelet von willebrand factor.platelet lysates from five patients with a form of type iib von willebrand's disease (vwd), associated with spontaneous platelet aggregation and thrombocytopenia, induced platelet aggregation of normal and other vwd's platelet-rich plasma (prp). platelet lysate from normals, type i or type iia vwd did not cause platelet aggregation of normal prp. when polyclonal monospecific antibodies directed against plasma von willebrand factor (vwf) were incubated with the type iib platelet lysate, they inhi ...20092784325
[single photon emission computed tomography by using n-isopropyl-p-[123i]-iodoamphetamine and 99mtc-hexamethyl propyleneamine oxime in a patient with herpes simplex encephalitis].single photon emission computed tomographies (spects) by using n-isopropyl-p-[123i-imp]-iodo-amphetamine (123i-imp) and 99mtc-hexamethyl propyleneamine oxime (99mtc-hm-pao) were serially performed in a 70 yrs. old male with herpes simplex encephalitis (hse), and the chronological changes of accumulations were studied. accumulations of both 123i-imp and 99mtc-hm-pao increased initially, and then decreased with the stage of hse being advanced. the sequential appearance of the lesion in hse with 12 ...20092786584
reversal of rejection-induced coronary vasculitis detected early after heart transplantation with increased immunosuppression.four patients who underwent heart transplantation, in whom coronary obstruction was seen early after transplantation, are described. repeated acute rejection episodes were detected within the first 2 months in each patient. coronary obstruction or ischemia was shown through a combination of t1-201 isotopic study findings, evidence of vasculitis of a small coronary arteriole seen at endomyocardial biopsy, or coronary angiographic results. vigorous treatment for rejection (antithymocyte globulin a ...20092795284
extensive cerebral calcification and retinal changes in pseudohypoparathyroidism.the case of a 41-year-old woman with cerebral calcification of a rather unusual extent is reported. this condition was associated with mental deficiency, pseudohypoparathyroidism and albright's hereditary osteodystrophy. four years later hypothyroidism was diagnosed. visual impairment and electroretinogram abnormality suggested a retinopathy involving mostly rods. despite their rarity, pseudohypoparathyroidism and albright's hereditary osteodystrophy are of major interest, since they represent t ...19892809648
effects of the antiglucocorticoid ru 486 on adrenal function in dogs.we studied the antiglucocorticoid effects of ru 486 given orally in doses of 5 (low), 20 (intermediate), and 50 mg/kg (high) daily for 10 days to seven female mongrel dogs. no changes in plasma acth or cortisol levels were produced by the 5 mg/kg dose. plasma acth levels increased 3-fold with both intermediate and high dosages. plasma cortisol levels rose 4-fold (p less than 0.05) within 2 days of commencing the high dose schedule and within 3 days with the intermediate dosage. plasma aldosteron ...19882832437
effects of the antiglucocorticoid ru 486 on adrenal function in dogs.we studied the antiglucocorticoid effects of ru 486 given orally in doses of 5 (low), 20 (intermediate), and 50 mg/kg (high) daily for 10 days to seven female mongrel dogs. no changes in plasma acth or cortisol levels were produced by the 5 mg/kg dose. plasma acth levels increased 3-fold with both intermediate and high dosages. plasma cortisol levels rose 4-fold (p less than 0.05) within 2 days of commencing the high dose schedule and within 3 days with the intermediate dosage. plasma aldosteron ...19882832437
[cell distribution and macrophage function in bronchoalveolar lavage of patients with sarcoidosis and lung tumors].bal was performed to differentiate cases of sarcoidosis and bronchial carcinoma. significant differences in the cell differentiation are stated. an increase of spontaneous interleukin production seems to be another sign of activity of sarcoidosis.20102833039
[human chorionic prealbumin: its identification, physicochemical properties and detection in the blood serum in trophoblastic disease].human chorionic prealbumin (hcpa) was immunochemically identified and isolated in pure form from immature placenta, particularly, from chorion. comparative immunodiffusion analysis shows that hcpa differs from the known placenta-specific proteins. hcpa is a glycoprotein with mw about 100 kd determined by gel-filtration and 45 kd by sds polyacrylamide gel electrophoresis. by immunodiffusion hcpa was not found in fetal and adult tissues and in biological fluids. hcpa was discovered in patients wit ...19882848598
intracellular crystal formation in bacteroides nodosus.an intracellular crystalline structure was found in at least two strains of bacteroides nodosus. the inclusion appeared to be associated with good growth of the organism under optimum conditions following selective passage of rough colonies containing highly fimbriate cells. several morphological forms of the inclusion were noted. indiscriminate subculture of crystal-forming cultures led to the loss of this particular property indicating a genetically controlled system of either bacterial or bac ...19882854148
motility in relation to virulence of bacteroides nodosus.fourteen bacteroides nodosus isolates from footrot lesions of sheep were examined microscopically and all were found to have twitching motility. the mean percentage of cells showing motility was 40% and 9% for virulent and benign strains, respectively. this corresponded with mean agar colony diameters of 17 mm and 7 mm, respectively, for these strains. two strains of intermediate virulence had values of motility and colony diameter similar to the benign strains. however, the intermediate and the ...19852858936
fimbriae from the oral anaerobe bacteroides gingivalis: physical, chemical, and immunological properties.circular dichroism spectra indicated the predominance of beta-sheet structure in bacteroides gingivalis fimbriae regardless of the presence of sodium dodecyl sulfate. by using a computer program, the alpha-helix, beta-sheet, and beta-turn contents and the remainder were estimated to be 0, 55, 18, and 27%, respectively, judging from the circular dichroism spectra of the fimbriae. heating for 5 min at 100 degrees c in sodium dodecyl sulfate was necessary to denature the fimbriae into their constit ...19852862134
legionella in power station cooling waters. 19852862486
differences between breeds of sheep in their responses to bacteroides nodosus vaccines.in a field experiment on irrigated pasture, sheep of several breeds were vaccinated twice, subcutaneously, in the upper neck, with bacteroides nodosus vaccine containing either depiliated cells (dc vaccine), or whole, piliated cells (wc vaccine) and the responses were measured over the following 14 weeks. dc vaccine was as effective as wc vaccine in protecting against the development of foot-rot under conditions of moderate challenge, although the wc vaccine induced significantly higher pilus ag ...19852862860
the protection given by pilus and whole cell vaccines of bacteroides nodosus strain 198 against ovine foot-rot induced by strains of different serogroups.a highly purified pilus vaccine prepared from cells of bacteroides nodosus strain 198 provided a high level of protection against homologous challenge and small, not statistically significant, levels of protection against challenge with 4 other strains each from different serogroups. in a second experiment, a partially purified pilus vaccine from strain 198 induced significant immunity to 1 of 4 heterologous strains which were different from those used in the first experiment. in a third experim ...19852864040
expression of the pilin gene from bacteroides nodosus in escherichia coli.bacterial plasmids that direct the expression in escherichia coli of the pilin of bacteroides nodosus were constructed. the quantity of pilin produced was greater than that of the pilin synthesized by b. nodosus, but no surface structural pili were present; pilin was found associated with the inner membrane of e. coli. vaccination of sheep with e. coli containing pilin elicited increases in agglutinating and enzyme-linked immunosorbent assay antibody titers, which in turn were lower than the tit ...19862867042
electrophoretic mobility of bacteroides nodosus pilus antigens. 19862870704
nucleotide sequence of the gene encoding the two-subunit pilin of bacteroides nodosus 265.the nucleotide sequence of the gene encoding pilin from bacteroides nodosus 265 has been determined. the pilin is encoded by a single-copy gene, from which can be predicted a prepilin comprising a single protein chain of mr 16,637. the prepilin sequence differs in several respects from the mature protein sequence. seven additional n-terminal amino acid residues are present in prepilin, whereas residue 8, phenylalanine, undergoes posttranslational modification to become the n-methylated amino-ter ...19862873127
cross-protection from bacteroides nodosus vaccines and the interaction of pili and adjuvants.the effects of vaccination of merino sheep with the purified pili or the whole cells of bacteroides nodosus strain 198, either in oil or alum-oil adjuvant, on the severity of foot-rot induced with the homologous strain (198) and a heterologous strain (217) were determined in a field experiment, on flood irrigated pasture. the efficacy of the whole cell vaccines was comparable to that of purified pili vaccines, against homologous challenge, when both had a similar content of pilus antigen althoug ...19862874786
expression of pili from bacteroides nodosus in pseudomonas aeruginosa.the pili of bacteroides nodosus, the causative agent of ovine footrot, constitute the major host-protective immunogen against homologous serotypic challenge. the pilin gene from b. nodosus 198 has been cloned and morphologically expressed as extracellular pili in pseudomonas aeruginosa by using a plasmid-borne, thermoregulated expression system. b. nodosus pilin could not be detected in cultures of p. aeruginosa grown at 32 degrees c, but after induction at 37 degrees c, b. nodosus pili were exp ...19862877967
morphogenetic expression of bacteroides nodosus fimbriae in pseudomonas aeruginosa.type 4 fimbriae are found in a range of pathogenic bacteria, including bacteroides nodosus, moraxella bovis, neisseria gonorrhoeae, and pseudomonas aeruginosa. the structural subunits of these fimbriae all contain a highly conserved hydrophobic amino-terminal sequence preceding a variable hydrophilic carboxy-terminal region. we show here that recombinant p. aeruginosa cells containing the b. nodosus fimbrial subunit gene under the control of a strong promoter (pl, from bacteriophage lambda) prod ...19872878919
the pathogenicity and cultural characteristics of virulent, intermediate and benign strains of bacteroides nodosus causing ovine foot-rot.the relationship between the cultural and biochemical characteristics of 22 strains of bacteroides nodosus and their virulence for sheep was examined. virulent, intermediate and benign strains were recognised. although there was some relationship between virulence and colony morphology on hoof medium with 4% agar, colonies of one virulent and 4 intermediate strains resembled those of benign strains. however, on hoof medium with 2% agar and on blood euonagar, colonies of this virulent and one int ...19862879527
a bacteroides nodosus pili vaccine produced by recombinant dna for the prevention and treatment of foot-rot in sheep. 19872883966
western blot (immunoblot) analysis of the fimbrial antigens of bacteroides nodosus.the roles of the fimbrial subunit and the putative basal protein antigens in the serological classification of bacteroides nodosus have been examined by western blot (immunoblot)-antibody binding studies of fimbriae isolated from a wide range of strains representative of different serogroups and serotypes. fimbrial subunits were recognized by antiserum against the homologous serogroup but not generally by heterologous antisera, whereas recognition of the basal antigen was independent of serologi ...19872887544
nucleotide sequence of the pilin gene from bacteroides nodosus strain 238 (serogroup g). 19872889185
protection of sheep against footrot with a recombinant dna-based fimbrial vaccine.recombinant pseudomonas aeruginosa cells containing the bacteroides nodosus fimbrial subunit gene under the transcriptional control of a strong promoter produce large amounts of b. nodosus-type fimbriae. we have carried out vaccination trials which show that these fimbriae are just as effective as either natural fimbriae or whole cell preparations of b. nodosus in inducing protective immunity against homologous footrot challenge. the recombinant-produced fimbriae are also effective therapeutical ...19872891214
efficacy against footrot of a bacteroides nodosus 265 (serogroup h) pilus vaccine expressed in pseudomonas aeruginosa.pili of bacteroides nodosus 265 (serogroup h) were expressed in pseudomonas aeruginosa both alone and in combination with pili from b. nodosus 198 (serogroup a). pilin genes from b. nodosus were introduced on plasmid-borne, thermoregulated expression systems, either singly or as tandem genes from two separate strains in a single transcription unit. despite the absence of a posttranslational cleavage of pilin which occurs in b. nodosus, pili prepared from p. aeruginosa harboring the pilin gene of ...19882893772
expression of multiple types of n-methyl phe pili in pseudomonas aeruginosa.the nature of pili synthesized by pseudomonas aeruginosa when plasmid-borne genes of homologous pilins from bacteroides nodosus are introduced as thermoregulated expression systems has been ascertained. expression of b. nodosus pili inhibited the production of indigenous p. aeruginosa pili, and an organism harbouring pilin genes from two strains of b. nodosus produced two serologically distinct populations of pili on each cell. simultaneous production of both indigenous and foreign pili was achi ...19872896292
[an immunological study of human t-cell leukemia virus type i (htlv-i) infection (ii)--radioimmunoprecipitation and sds-polyacrylamide gel electrophoretic analysis of antibody of carriers]. 19872897404
pilins of bacteroides nodosus: molecular basis of serotypic variation and relationships to other bacterial pilins. 19882901028
berger's disease without iga deposits? 20102918964
minimal incision techniques for digital deformities.we have presented basic minimal incision approaches to the more common digital deformities. we feel that with proper evaluation of the deformity and the patient, minimal incision surgery techniques give excellent long-term results with several advantages. these advantages include: less discomfort due to less surgical dissection. less need for internal fixation by careful use of compression dressings in the immediate postoperative period along with early ambulation. less disability. compression d ...20102937517
chronic pain in psychiatric [correction of psychotic] patients. 20102942045
[experience in serving the child population in hard-to-reach areas of kazakhstan]. 20102975412
[the function of the neutrophil granulocyte in acne vulgaris].twenty seven patients with acne vulgaris were studied. of them, 10 had minimal lesions and 17 had severe inflammatory lesions: nodulocystic, and conglobata. nbt and lysosomal neutrophil function was performed. the results shows a significative decreased values for the three test in patients with inflammatory lesions compared to patients with non-inflammatory lesions. the values for chemotactic function was 56.23 and 93%, for nbt test 50.82 and 93% and for lysosomal activity 60.88 and 88.9%, resp ...20102976441
technique for measurement of one-dimensional instantaneous ablation velocity.an oscillating mirror scanned a he-ne laser beam along the length of a thin rod while the rod was ablated by an argon laser beam. the shadow of the scanning beam on an image plane provides a picture of the instantaneous ablation velocity of the rod. this configuration provides a unique method for investigating one-dimensional ablation.20102976448
isolation of a specific mu-opiate receptor peptide, morphiceptin, from an enzymatic digest of milk proteins.specific radioimmunoassays have been developed for the measurement of naturally occurring morphiceptin and beta-casomorphin. these peptides and related exorphins were isolated from an enzymatic digest of caseins by chromatographic techniques including gel filtration, hydrophobic column and multiple-step high pressure liquid chromatography. three exorphins were purified and characterized in their radioimmunological, biological, and chemical properties. they were identified as morphiceptin, beta-c ...19852991261
felv-induced feline acquired immune deficiency syndrome. a model for human aids. 19863008168
[ecology and epidemiology of transmissible viruses of sandflies in italy]. 19863019208
primary biliary cirrhosis: assessment of the quantitative importance of the adenine nucleotide translocator protein as a major mitochondrial antigen.the adenine nucleotide translocator protein (ant) is the first well-characterized mitochondrial polypeptide to be identified as an antigen for antimitochondrial autoantibodies (ama) in pbc sera. because of the potential use for a highly purified antigen as a tool in studying the aetiology of pbc, we have undertaken an assessment of the quantitative importance of ant as a pbc-specific mitochondrial antigen. immunoblotting and elisa techniques were used. both methods reveal pbc antibodies against ...19863028680
biphasic radiation-sensitivity of the transplantation immunity for rejection of an allogeneic ascites tumor.transplantation immunity for second-set rejection of an allogeneic ascites tumor was induced by sensitizing mice with h-2-identical allogeneic spleen cells, and radiation-sensitivity of this immunity was studied. the immunity was not severely affected by 400 rads whole-body x-ray irradiation given at one day before the initial antigenic stimulation. in contrast, it was totally inactivated by 300-400 rads irradiation that was given one day before tumor challenge. an adoptive cell transfer experim ...20113042613
[vesicorenal reflux following endoscopic treatment of vesical tumors. developmental and therapeutic complications].a survey of 107 patients treated for bladder papillomatosis, 78 of which recurred, confirmed the frequency of appearance of an iatrogenic reflux (28 cases: 26%). the main explanations for its onset are resection and orificial sclerosis. two consequences of reflux are discussed. one is very probable: the development of tumoral lesions in the upper excretory pathways. noted in 7 (25%) of the 28 cases, these high tumors can be partly explained by the mechanism of cell implantation, grafts being asc ...20113102620
drug-resistant tuberculosis in a southern california hospital. trends from 1969 to 1984.resistance to one or more antituberculosis drugs was found in 98 of 281 (35%) patients hospitalized at harbor-ucla with culture-positive tuberculosis between 1980 and 1984. resistance to antituberculosis drugs occurred in 23% of patients who had not been previously treated, whereas previously treated patients had a 59% rate of resistance. the overall rates of drug resistance had not significantly changed from prior studies at this hospital. drug resistance was also found in patients with extrapu ...19873109291
an analysis of the organization and evolution of type 4 fimbrial (mephe) subunit proteins.we have analyzed and compared the amino acid sequences of the type 4 fimbrial subunits from pseudomonas aeruginosa. moraxella bovis, m. nonliquefaciens, bacteroides nodosus, neisseria gonorrhoeae, and n. meningitidis. we propose a consensus sequence for the highly conserved amino-terminal regions of these proteins. in the variable regions, a domain corresponding to an epitope common to n. gonorrhoeae and n. meningitidis fimbriae is conserved, both in sequence and in environment, in fimbrial subu ...19873118043
future developments in the food industry. 20113123680
[therapy of alopecia areata with diphenylcyclopropenone].induction and maintenance of contact dermatitis of the scalp has proved effective in producing regrowth of hair in patients with alopecia areata. we observed regrowth of hair in 17 out of 20 patients after local application of the contact allergen, diphenylcyclopropenone. only 3 patients were treated without success. in 3 patients regrowth of hair was also seen in areas that were not treated with diphenylcyclopropenone, suggesting that this treatment has an additional systemic effect. patient ac ...20113160683
[assessment of fitness for airplane and ship travel]. 20113176547
postradiation soft tissue sarcomas. an analysis of 53 cases.the clinicopathologic features of 53 cases of postradiation soft tissue sarcoma (prs) were correlated with the physical characteristics of the administered radiation. all but three patients received radiation for malignant processes. of the secondary sarcomas, malignant fibrous histiocytoma (mfh) accounted for 36 cases (68%), followed by seven extraskeletal osteosarcomas (13%), six fibrosarcomas (11%), two malignant schwannomas (4%), one extraskeletal chondrosarcoma, and one angiosarcoma. the se ...20113179948
to switch or not to switch? the senning alternative.we analyzed the fate of 100 consecutive patients with simple arterial transposition who were admitted within the first 2 weeks of life to the hospital for sick children during the period 1978-1986. in contrast to current practice, these patients were managed with the objective of performing a senning operation as the definitive procedure. five of these 100 patients died on the first day of life of sequelae of perinatal hypoxia, four died within the first month of life (often of complications of ...20113180387
nucleotide sequence of the pilin gene of bacteroides nodosus 340 (serogroup d) and implications for the relatedness of serogroups.the gene encoding pilin of bacteroides nodosus 340 has been isolated and the nucleotide sequence determined. the gene is present as a single copy within the b. nodosus genome and a protein of mr 16683 can be predicted from the proposed coding region. a comparison of the predicted amino acid sequence with pilin from other strains of b. nodosus indicated that the protein of strain 340 (serogroup d) has a high degree of similarity with pilin of strain 265 (serogroup h). the degree of similarity bet ...19883183618
urinary peristalsis investigated by radionuclide and x-ray methods: a comparison. 20113187425
antibody responses of sheep vaccinated with foot rot vaccines.enzyme-linked immunosorbent assay (elisa) and crossed immunoelectrophoresis (iep) were used to investigate antibody responses of sheep vaccinated with a double adjuvanted or single adjuvanted commercial foot rot vaccine. elisa detected an antibody response of greater magnitude to the double adjuvant vaccine compared with the single adjuvant vaccine. sera from sheep vaccinated with double adjuvant vaccine recognised at least six antigens of bacteroides nodosus in crossed iep while sera from the s ...19883222555
a taxonomic revision of the small catarrhine primates from the early miocene of east africa.this paper presents a detailed systematic revision of the small catarrhine primates from the early miocene of east africa, recovered from sites in western kenya and in uganda dated at between 22 and 17 m.y. revised diagnoses and amended hypodigms for each of the species are presented. in addition to the currently identified taxa, limnopithecus legetet hopwood, 1933, dendropithecus macinnesi (le gros clark and leakey, 1950) and micropithecus clarki fleagle and simons, 1978, two further species ar ...20113234984
amino acid sequence similarity between drosophila acetylcholinesterase and the active site region of trypsin. 20113241671
[total residue analysis of amitraz in the rabbit tissue by gas chromatography]. 19883243539
onchocerciasis in sierra leone 3: relationships between eye lesions and microfilarial prevalence and intensity.the relationship between severe onchocercal eye lesions (iritis, sclerosing keratitis, optic atrophy and choroidoretinitis) and (i) the prevalence and intensity of microfilariae (mf) of onchocerca volvulus in skin snips from the iliac crest and outer canthus, and (ii) the prevalence of mf in the cornea and anterior chamber of the eye, was studied in 1414 persons from forest and savanna villages and 312 attenders at eye clinics. ecologically the savanna of sierra leone more closely resembles the ...19883256114
production of mouse monoclonal antibodies for the analysis of idiotypes in serum of patients with chronic lymphatic leukaemia.in this report a simple procedure for the production of murine monoclonal antibodies (moab) against the idiotype of malignant b cells is described. mice were immunized with lymphoid cells from patients with b-cell chronic lymphocytic leukaemia (b-cll). after fusion of the spleen cells, hybridoma supernatants were screened for anti-idiotypic moab in elisa with immunoglobulins obtained from tumour-cell lysates, xenohybridomas and patients' sera. the anti-idiotypic moab were used to study tumour ce ...19883257881
acute effects of surgery on carbohydrate production and utilization in the fed rat.1. the work utilized a model of uncomplicated abdominal surgery (laparotomy under ether anaesthesia) to delineate the effects of abdominal trauma on glucose homoeostasis in the fed rat. 2. regulation of glucose production and utilization was investigated by observing the response to the administration of glucose, insulin plus glucose and 5-methylpyrazole 3-carboxylic acid. 3. glucose administration suppressed hepatic glucose output as assessed by portal-venous concentration differences in contro ...19883276438
redressing the balance. 20123292931
the man behind the eponym. paul langerhans. life and work. part iv: publications. 19873307477
glycosaminoglycan degradation. 20123310531
cytosolic calcium management, regulation and biologic significance in epithelial tissue. 20123347196
who decides which lens is best? 20123351183
[toxicity of prometryne in the lactation period in rats]. 19883369200
genetic-associated resistance to foot rot in selected targhee sheep.three targhee rams obtained from the ohio agricultural and experimental station had been identified as foot rot resistant on the basis of results of challenge exposure. in the first breeding trial, when rams were bred to 20 foot rot-susceptible ewes, the percentages of foot rot-resistant offspring from the 3 foot rot-resistant rams were 68, 82, and 100, compared with 55 and 60 for foot rot-resistant offspring from 2 known foot rot-susceptible rams. in the second year, the foot rot-resistant rams ...19883372300
[study of the effect of antitumor agents on cell cycle traverse by flow cytometry].the effect of antitumor agents on the cell cycle traverse of cultured fl cells, a monolayer culture line derived from human amnion, was investigated by flow cytometry (fcm) in combination with simultaneous determination of total cell number, viability, mitotic index and labeling index by [3h]tdr. the results obtained can be summarized as follows: antimetabolites prolonged the duration of the s phase at a low dose, while at a high dose they decreased the rate of progression from the g1 to s phase ...19883389824
reduced early diastolic extension in the infarcted portion in patients with old myocardial infarction.to study relaxation characteristics of the infarcted myocardium, cyclic changes in the global left ventricular (lv) volume were measured in 20 patients with old myocardial infarction (omi) and 17 normals (normal) and those in the regional segment length were measured in 9 patients with anterior old myocardial infarction (anterior omi) and 11 normals. the lv volume was calculated by using biplane lv cineangiograms. the regional segment length was calculated by measuring the spatial length between ...20123411764
estimating the soluble enzyme activity in brain tissue. 19883416451
analytic vs. holistic approach--methodological problem in prospective neuroscience. 20123421059
diagnosis of congenital toxoplasmosis in ovine foetuses. 19873426476
rapid and fine adjustment of corticosteroidogenesis operating in the adrenal gland of the mongolian gerbil (meriones unguiculatus) superfused in-vitro.corticosteroid release from adrenals of male adult mongolian gerbils (meriones unguiculatus) has been studied during continuous and discontinuous in-vitro superfusion. corticosteroid output from glands of untreated animals with plasma corticosteroid levels below 300 ng/ml was 3.3 +/- 0.3 ng/adrenal pair/min and decreased only slightly with the length of superfusion (60 min: 3.1 +2- 0.3 ng/adrenal pair/min). in-vitro secretion was significantly higher from adrenals of animals which had corticoste ...19873428359
[effect of prednisolone on hormonal function of the fetoplacental unit in the third trimester of pregnancy. ii. effect of prednisolone on progesterone, placental gonadotropin and placental lactogen levels in the blood of pregnant women]. 20123428656
cardiac rupture secondary to isolated midcircumflex artery obstruction. 20123480457
comparative antigenic analysis of extracellular proteins of bacteroides nodosus isolated from virulent and benign ovine footrot.antigens in the extracellular protein (ecp) complexes of bacteroides nodosus, isolated from sheep with either benign or virulent footrot, were studied by immunoelectrophoresis (iep). rabbit antisera against ecp from virulent and benign strains, were used in homologous and heterologous crossed iep. four precipitin peaks unique to the virulent strain, and five peaks unique to the benign strain were identified. in an attempt to characterize the different antigens in ecp, rabbit antisera were raised ...19863529606
multiple dose insulin regimen using the novopen. 20133534657
biochemical and functional characterization of the rat liver glucose-transport system. comparisons with the adipocyte glucose-transport system.the properties of the glucose-transport systems in rat adipocytes and hepatocytes were compared in cells prepared from the same animals. hormones and other agents which cause a large stimulation of 3-o-methylglucose transport in adipocytes were without acute effect in hepatocytes. hepatocytes displayed a lower affinity for 3-o-methylglucose (20 mm) and alternative substrates than adipocytes (6 mm), whereas inhibitor affinities were similar in both cell types. the concentration and distribution o ...19863548706
traumatic disruptions of right upper bronchus and truncus intermedius in a five-year-old boy.a case of uncommon ruptures of right upper bronchus and truncus intermedius in a 5-year-old boy is presented. two operations provided bronchial continuity, with insertion of an 18-gauge catheter required at the second operation. problems in anastomosis and early postoperative management in small airways of growing children are also discussed.20123560280
metoclopramide decreases baroreflex sensitivity in patients with essential hypertension.the effect of metoclopramide (10 mg, iv.) or physiological saline on the exercise-induced (standardized bicycle ergometry) increase in blood pressure and heart rate of patients with essential hypertension was investigated in a double blind, randomized, self controlled study. metoclopramide had no effect on the exercise-induced increase in blood pressure but significantly enhanced the tachycardia due to ergometry after 4-6 min exercise. the mean slope of linear regression lines calculated from th ...20133561160
macromolecules can pass through occluding junctions of rat ileal epithelium during cholinergic stimulation.crypt, but not villus, goblet cells in the ileum accelerate their secretion of mucus within 5 min following cholinergic stimulation. this study was done to determine whether the macromolecular permeability and structure of occluding junctions in the ileum are altered during accelerated secretion. rats were injected intravenously with horseradish peroxidase followed by carbachol (250 micrograms/kg, subcutaneous) and the intestinal mucosa was fixed 3-12 min later. in control mucosa (saline-injecte ...19873568101
observations on the binding of lanthanides and calcium to vitamin d-dependent chick intestinal calcium-binding protein. implications regarding calcium-binding protein function.the binding of calcium and terbium to purified chick vitamin d-dependent intestinal calcium-binding protein was studied by terbium fluorescence, circular dichroism, and intrinsic protein fluorescence techniques. calcium-binding protein bound, with high affinity, at least 3 mol of terbium/mol of protein; numerous low affinity terbium-binding sites were also noted. the three highest affinity sites were resolved into one very high affinity site (site a) and two other sites (sites b and c) with slig ...19873571269
vaccination against lumpy jaw and measurement of antibody response in wallabies (macropus eugenii).successful protection against lumpy jaw disease in a colony of captive wallabies (macropus eugenii) was induced by vaccination with a commercial ovine footrot vaccine. no mortalities attributable to lumpy jaw were observed in 69 vaccinated animals while six of 42 unvaccinated control wallabies died of the disease. vaccinated animals exhibited significant increases in antibody titres to bacteroides nodosus after the first and second doses of vaccine. titres were measured by an enzyme-linked immun ...19873629891
why hospice nurses are a breed apart. 20133645767
[we can make the conference effective]. 20133650548
mechanisms of absorption, transport and tissue uptake of rrr-alpha-tocopherol and d-gamma-tocopherol in the white rat.the metabolism of alpha- and gamma-tocopherol was studied in three groups of rats that were fed a modified ain-76 diet containing normal (ne, 0.2 g alpha-tocopherol/kg), high (he, 1.0 g alpha-tocopherol/kg) or low (le, less than 0.02 alpha-tocopherol/kg) vitamin e for 3 mo. after 1, 2 and 3 d of an oral dose of 20 mg of alpha-tocopherol, gamma-tocopherol or both, the levels of the two vitamers were measured in plasma and tissues and in some cases in isolated microsomal and mitochondrial fraction ...19873655936
[realities in the diagnosis of bronchial carcinoma in clinical and general practice].in 100 patients with lung cancer the diagnostic procedure, results of clinical staging and therapeutic sequelae were analysed retrospectively and compared to a similar group of patients 10 years previously. during the 10 years' interval there was a remarkable shortening of the time between the onset of symptoms and the diagnosis, from 20 weeks to the present 10 weeks. despite this acceleration the number of patients undergoing curative surgical resection increased only from 15 to 17%. inoperabil ...20133672088
factors influencing the assay of inoue-melnick virus.we describe factors influencing the assay of inoue-melnick virus (imv) and practical comments for its assay. mrc-5 cells at a population doubling level (pdl) of more than 32 were more sensitive than younger cells for demonstrating cytopathic effect (cpe) of the virus. the pdl of mrc-5 cells also influenced the virus yield, particularly when the amount of viral inoculum was small. cells at younger pdl produced less virus. the appearance of cpe and the virus yield were inhibited by increasing the ...20133680463
boosting protection. 20133697254
monoamine oxidase inhibitors. 20133697591
anorectal function following colo-anal sleeve anastomosis for chronic radiation injury to the rectum.anorectal manometry and electrophysiological studies of the pelvic floor were performed in eight patients who had undergone anterior resection of the rectum with mucosal proctectomy and colo-anal sleeve anastomosis for radiation rectal injury. there is a severe reduction in the compliance of the neorectum and in the maximal tolerable volume. maximum basal anal canal pressure and physiological sphincter length are also significantly reduced although the 'squeeze' pressure of the external anal sph ...20133697659
[functional activity of natural killers in viral hepatitis a].the direct cytotoxic test with the use of c and neoplastic cells of human myeloleukemia k-562 was employed to examine the activity of natural killers (nk) in 234 patients with viral hepatitis and in 51 healthy subjects as control. it was ascertained that in viral hepatitis, the functional activity of nk was appreciably altered. at the disease onset it tended toward lowering, whereas before the recovery it consistently increased. in cyclic hepatitis, the cytotoxicity rose considerably 2 to 3 week ...19863704941
compulsive attentive behavior after lesion of the ventral striatum in the cat: a behavioral and electrophysiological study.bilateral lesions of the nucleus accumbens in cat elicited the following changes: preservation in tests requiring focused attention, with difficulty to shift to other targets; paucity of movements, animals displaying moderate hypokinesia and loss of reaction to changes in the environment. these symptoms were accompanied by a significant increase in the amount of beta rhythms, an activity that has been shown to be concomitant with the development of focused attentive behavior. the observed behavi ...19863709743
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