Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| hepatic necrobacillosis. report of a case resembling metastatic tumor. | a 47-year-old man had multiple pyogenic liver abscesses from which the anaerobic bacteria fusobacterium nucleatum and peptostreptococcus were isolated. the clinical course, diagnostic evaluation, and appearance of the lesions at surgery suggested metastatic tumor. histologically, the lesions consisted of necrotic liver tissue surrounded by zones of acute and chronic inflammation and fibrous connective tissue closely resembling the lesions of hepatic necrobacillosis attributable to f necrophorum. ... | 1977 | 869652 |
| penetration of the blood brain barrier by metronidazole and tinidazole. | 1977 | 873873 | |
| [outbreak of necrobacillosis of swine]. | 1977 | 878292 | |
| urease assay and urease-producing species of anaerobes in the bovine rumen and human feces. | a growth medium and test were developed for rapid detection of urease in fermentative anaerobic bacteria. using nonselective rumen fluid roll-tube agar medium and the new test, it was confirmed that peptostreptococcus productus is often the most numerous urease-forming species in human feces. also, some fecal strains of ruminococcus albus, clostridium innocuum, and clostridium beijerinckii produced urease. single strains of fusobacterium prausnitzii, coprococcus catus, and streptococcus mitis th ... | 1977 | 879770 |
| fusobacterium in presumed actinomyces canaliculitis. | based on stained smears of material obtained from the canaliculus, three cases of canaliculitis were presumed to be caused by actinomyces. cultures of these cases showed fusobacterium to be the probable infectious agent producing the disease. | 1977 | 900231 |
| fecal microbial flora in seventh day adventist populations and control subjects. | a comparison of 13 vegetarian seventh day adventists with 14 nonvegetarian adventists revealed relatively few statistically significant differences in fecal flora. a separate study involved a comparison of vegetarian adventists (49 subjects), nonvegetarian adventists (45), and non-adventists on a conventional american diet (31) re: the incidence of the c. paraputrificum group in the fecal flora. the adventist groups had significantly fewer c. septicum and c. tertium isolates than the non-adventi ... | 1977 | 920638 |
| hepatic lesions and bacterial changes in mice during infection of fusobacterium necrophorum. | liver abscesses were induced in male albino mice within 1 week after intraperitoneal inoculation of viable fusobacterium necrophorum la19 culture. fusobacteremia was transitory and reached a peak 2 h after inoculation then sharply declined until its disappearance 24 h post inoculation. by contrast, the number of fusobacteria in the liver increased rapidly during the first 4 h post inoculation and continued to do so less rapidly until the last sampling time (48 h post inoculation). there were sma ... | 1977 | 922598 |
| modified lombard-dowell broth as a general growth medium. | a new liquid medium (modified lombard-dowell broth) was inoculated with stock culture strains of aerobic and anaerobic bacteria and compared with prereduced chopped-meat glucose inoculated with the same anaerobes. both broths were subcultured at 48 and 72 h to aerobic and anaerobic blood agar plates, and the numbers of colonies were compared after 48-h incubation of the agar plates. this was repeated with mixed cultures of both aerobes and anaerobes. for a period of 11 months all specimens recei ... | 1977 | 925150 |
| [necrobacillosis of the cattle in the irkutsk district]. | 1977 | 929951 | |
| [the bacteriodaceae flora in the faeces of pigs (author's transl)[]. | a total of 180 bacteroidaceae strains from the fecal specimens of 31 clinically healthy pigs aged 120 to 180 days from 4 farms were isolated in numbers of 10(8)-10(10) per gram feces and differentiated for their morphological, cultural and biochemical properties. 161 of these strains belonged to bacteroides ruminicola and related species, 10 to b. fragilis ss. fragilis, 3 to b. fragilis ss. vulgatus, 4 to fusobacterium necrogenes, 1 to f. mortiferum and 1 to a non-motile variant of f. novum. the ... | 1976 | 936825 |
| anaerobic bacteria from the large intestine of mice. | anaerobic bacteria from the colon of laboratory mice were enumerated and isolated using strict anaerobic techniques. direct microscopic counts revealed 4.4 x 10(10) organisms in each gram (wet weight) of colon contents. actual cultural counts averaged 3.2 x 10(10) organisms, which was 73% of the direct microscopic count. the tentatively identified genera were bacteroides, eubacterium, fusobacterium, lactobacillus, peptostreptococcus, and propionibacterium. strains of fusobacterium, lactobacillus ... | 1976 | 938042 |
| pathological changes produced by fusobacterium necrophorum in experimental infection of mice. | 1976 | 939825 | |
| an outbreak of diphtheria in boergoat kids. | during an outbreak of diphtheria or ulcerative stomatitis in young boergoat kids fusobacterium necrophorum was consistently isolated under anaerobic cultural conditions from material taken from the edges of the ulcerative lesions from all of the cases examined. corynebacterium pyogenes, staphylococcus aureus, actinobacillus lignieresi, moraxella spp. and lactobacillus spp. were also isolated anaerobically and/or aerobically. the typical symptoms and lesions were confirmed to the mouth, tongue an ... | 1976 | 940095 |
| anaerobic meningitis and bacteremia caused by fusobacterium species. | in the two cases of anaerobic meningitis and bacteremia caused by fusobacterium species described, upper respiratory tract infection preceded the onset of meningitis. isolation of the causative organism and appropriate antibiotic therapy resulted in cures in both patients. although extremely rare, these organisms should be considered as possible causative agents in meningitis when routine cultures are negative, and appropriate anaerobic culture techniques should be employed, especially when sinu ... | 1976 | 941888 |
| in vitro susceptibilities of anaerobic bacteria to josamycin. | a total of 132 strains of anaerobic bacteria were tested for susceptibility to josamycin, using a broth dilution technique. all strains of peptococcus species, peptostreptococcus species, and bacteroides fragilis were inhibited by 2 mug or less per ml. seventy percent of these susceptible strains were also killed by 2 mug or less of josamycin per ml. however, 2 of 12 clostridium species and 6 of 10 fusobacterium species had minimum inhibitory concentrations of 32 mug or more per ml. | 1976 | 949184 |
| comparison of the in vitro bactericidal activity of human serum and leukocytes against bacteroides fragilis and fusobacterium mortiferum in aerobic and anaerobic environments. | in aerobic and anaerobic in vitro environments, fusobacterium mortiferum was killed by human leukocytes or serum alone or in combination; clinical isolates of bacteroides fragilis were killed only by leukocytes in the presence of serum. | 1976 | 965101 |
| in vitro susceptibility of common clinical anaerobic and aerobic isolates against josamycin. | the in vitro susceptibility of 145 anaerobic clinical isolates and 96 gram-positive aerobic clinical isolates to josamycin, a new macrolide antibiotic, was studied using the agar dilution technique. ninety-five of the aerobes were susceptible to 1.56 mug or less of josamycin per ml. the median minimal inhibitory concentration of these organisms was </=0.39 mug/ml. the in vitro activity of josamycin against the anaerobes was compared with that of erythromycin, clindamycin, penicillin, and chloram ... | 1976 | 984766 |
| susceptibility of respiratory tract anaerobes to orally administered penicillins and cephalosporins. | anaerobic bacteria recovered from airway-related infections were tested by agar dilution against selected penicillins and cephalosporins available for oral administration. against 136 isolates, penicillins g and v showed comparable activity, particularly when pharmacological differences were considered. although many isolates were exquisitely susceptible to the penicillins, only 55% of the bacteroides species and 72% of all isolates were inhibited at 0.5 mug of penicillin g per ml. results for p ... | 1976 | 984805 |
| susceptibility of anaerobic bacteria to 23 antimicrobial agents. | the antimicrobial susceptibility of 492 anaerobic bacteria, the majority of which were recent clinical isolates, was determined by the agar dilution technique. penicillin g was active against most of the strains tested at 32 u or less/ml, but only 72% of bacteroides fragilis strains were susceptible at this level and 9% required 256 u or more/ml. ampicillin was effective against most of the strains except b. fragilis at 16 mug or less/ml. amoxicillin was active against only 31% of b. fragilis, 7 ... | 1976 | 984809 |
| bacteriology of bovine hepatic abscesses. | 1976 | 986506 | |
| bacteriology of the lower respiratory tract as determined by fiber-optic bronchoscopy and transtracheal aspiration. | for assessment of the validity of cultures of tracheobronchial secretions and exudates (tbse) obtained by fiber-optic bronchoscopy, the aerobic and anaerobic flora of expectorated saliva and tbse obtained by fiber-optic bronchoscopy from nine healthy volunteers and eight patients were compared with those obtained by fiber-optic bronchoscopy as well). normal volunteers yielded both aerobic and anaerobic bacteria in amounts usually less than 104.5 colony-forming units (cfu)/ml in tbse obtained by ... | 1976 | 993617 |
| a simple method for rapid identification of sphaerophorus necrophorus isolates. | 1976 | 1004237 | |
| [significance of the fusospirillum complex (plaut-vincent angina)]. | the results are discussed of a retrospective study of 126 patients by whom an excess of the fusospirochaetal complex was found by direct microscopic examination of tonsillar material. these bacteria are not only found in unilateral ulcero-necrotic tonsillitis, but also in different other tonsillar and general diseases. vincent's angina appears almost exclusively in young persons, aged from 16 to 25 years; in the adolescence (16-20 years) it forms about 40% of all cases of acute tonsillitis. the ... | 1976 | 1015288 |
| [etiology of pathological changes in the liver of fattened geese]. | 1976 | 1017560 | |
| [oral vibrions method of isolation and demonstration of their relation to sherophorus fusiformis]. | 1976 | 1020709 | |
| in vivo protection of fusobacterium necrophorum from penicillin by bacteroides fragilis. | a mixed infection of bacteroides fragilis and fusobacterium necrophorum was resistant to treatment with penicillin even though a pure f. necrophorum infection could be successfully treated with penicillin. since b. fragilis alone did not produce infection, these results indicate that b. fragilis can protect f. necrophorum from penicillin in vivo. the extent of protection afforded by a strain of b. fragilis was related to its level of resistance to penicillin. only a few cells of b. fragilis were ... | 1975 | 1041218 |
| antimicrobial therapy of anaerobic infections. | 1975 | 1041514 | |
| [changes of antimicrobial susceptibility of anaerobic bacteria from clinical specimens (author's transl)]. | the susceptibility to several commonly used antimicrobial agents was examined on approximately 900 isolates of various anaerobes from clinical specimens between october 1965 to may 1975, and the changes of susceptibility were investigated. antimicrobial agents tested were penicillin g (pc-g), ampicillin (ab-pc), cephaloridine (cer), erythromycin (em), josamycin (jm), lincomycin (lcm), clindamycin (cldm), chloramphenicol (cp) and tetracycline (tc). and thiamphenicol (tp) and doxycycline (dotc) we ... | 1975 | 1042183 |
| antibiotic treatment of oral anaerobic infections. | 1975 | 1056466 | |
| the predominant cultivable organisms in juvenile periodontitis. | quantitative and qualitative examinations of the predominant cultivable microflora of the advanced tissue destruction (pocket) associated with juvenile periodontitis and of control pockets without loss of attachment were carried out by using anaerobic tube culture technique. the microflora from the control sites consisted primarily of streptococci, gram-negative rods, and gram-positive rods. in contrast, the test pockets had a relatively stable and characteristic microflora, dominated by various ... | 1976 | 1061986 |
| complications of peritonsillar abscess due to fusobacterium necrophorum. | 1976 | 1063358 | |
| immunity in foot-rot infection. | 1976 | 1063947 | |
| soluble antigens of leptotrichia buccalis: their reaction with rabbit antisera. | 1975 | 1068997 | |
| case records of the massachusetts general hospital. weekly clinicopathological exercise. case 17-1975. | 1975 | 1090833 | |
| antimicrobial therapy in ruminants. | 1975 | 1091078 | |
| anaerobic infections of the female genital tract: prospects and perspectives. | 1975 | 1094357 | |
| treatment of anaerobic infections with metronidazole. | the results of treatment of 10 patients with anaerobic infections with metronidazole are presented. six patients were cured, three showed initial good response but circumstances required a change to another drug, and one patient did not respond. the unique spectrum of the drug, its pharmacology, and limitations are discussed. the results indicate that further clinical trials to determine the efficacy of metronidazole in the treatment of anerobic infections are indicated. | 1975 | 1096810 |
| bacterial studies of clindamycin-associated colitis. a preliminary report. | the cause of pseudomembraneous colitis is not known but has been attributed to an alteration in the microbial flora of the colon. to test this hypothesis, a blind, prospective study was undertaken in which fecal samples were cultured quantitatively for aerobic and anaerobic organisms. the patients from which these samples were taken were all receiving clindamycin and had diarrhea secondary to the use of the drug. we were able to show definite differences in the colonic microflora which correlate ... | 1975 | 1097297 |
| indirect fluorescent antibody procedure for the rapid detection and identification of bacteroides and fusobacterium in clinical specimens. | an indirect fluorescent antibody (ifa) technique was evaluated as a procedure for rapid detection and identification of members of the bacteroidaceae. antisera were prepared against 31 members of this family, including species of bacteroides and fusobacterium commonly isolated from human infections. the antisera had demonstrated species and/or subspecies specificity. thirty clinical specimens were studied. of 13 specimens yielding bacteroidaceae, for which antisera were available, 23 were presum ... | 1975 | 1102560 |
| anaerobic specimen transport device. | a device is described and evaluated for the anaerobic transport of clinical specimens. the device limits the amount of oxygen entering with the sample to a maximum of 2%, which is rapidly removed by reacting with hydrogen in the presence of a palladium catalyst. the viability on swabs of 12 species of anaerobes, four strains of facultative anaerobes and a strain of pseudomonas aeruginosa, was maintained during the length of the tests (24 or 48 h). the results demonstrated that this device protec ... | 1975 | 1104656 |
| evaluation of a test kit for identification of anaerobic bacteria. | a test kit for identification of anaerobic bacteria--api--has been compared for accuracy in individual tests and for identification on the genus or species level with pre-reduced anaerobically sterilized media methods on 241 anaerobic strains. the microsystem was found to be reliable and permits identification of the clinically most significance anaerobic bacteria if it is supplemented with other tests such as gaschromatographic analysis, morphology, lecithinase, lipase and antibiotic sensitivit ... | 1975 | 1105128 |
| significance of anaerobic bacteria isolated from the urinary tract. ii. experimental studies. | an attempt to cause retrograde urinary tract infection with bacteroides fragilis (a strain subcultured in artificial media) failed to produce any significant renal infection in rats. intravenous inoculation with fusobacterium (a strain subcultured in artificial media) also did not cause demonstrable renal infection in rats. nor could the anaerobic organism be demonstrated in the kidneys of these animals. animals receiving bacteroides (a strain subcultured in artificial media) inoculated directly ... | 1976 | 1107257 |
| necrobacillosis in deer and pronghorn antelope in saskatchewan. | 1975 | 1109764 | |
| characterization of endotoxin from fusobacterium necrophorun. | endotoxic lipopolysachharide (lps) was obtained from phenol-water extraction of cell walls prepared from mass-cultivated fusobacterium necrophorum. the lps was relatively free of nucleic acids and low in protein, and constituted about 4% of the cell walls. upon acid hydrolysis, some of the components detected were hexosamines (7.0%), neutral and reducing sugars (50.5%), heptose (6.4%), 2-keto-3-deoxyoctonate (0.8%), lipid a (21.0%), and phosphorus (1.7%). under electron microscopy the lps appear ... | 1975 | 1112618 |
| [experience in eradicating necrobacillosis on a state farm]. | 1975 | 1114669 | |
| biological characterization of fusobacterium necrophorum. cell fractions in preparation for toxin and immunization studies. | fusobacterium necrophorum isolated from bovine liver abscesses was grown in bulk at 37 c for 24 h under a strict anaerobic atmosphere. harvested washed cells were disrupted ultrasonically and fractionated by differential centrifugation into the intracellular (cytoplasm) and cell wall fractions. both intact cells and cell fractions induced generalized cytopathic effect on primary pig kidney cultures and caused a variety of signs of illness and/or death of intraperitoneally injected mice. the inta ... | 1975 | 1120608 |
| fusobacterium septicemia with otitis media and mastoiditis. | 1975 | 1124245 | |
| sphaerophorus necrophorus: laboratory model for the evaluation of chemotherapeutic agents in mice. | severe necro-purulent lesions were induced in mice following parenteral inoculation of sphaerophorus necrophorus. gross and histological changes observed in the lung, liver, and foot pad of infected mice were similar to those occurring naturally in cattle. the lesions could be prevented, cured or significantly reduced by the administration of chemotherapeutic agents such as sulfonamides, potentiated sulfonamide and antibiotics. the application of this novel laboratory model infection in the prim ... | 1975 | 1126167 |
| disk susceptibility testing of slow-growing anaerobic bacteria. | the susceptibility of 55 strains of slow-growing anaerobes to eight clinically useful or potentially useful antibiotics was determined by agar dilution and disk diffusion tests. strains of the genera peptococcus, peptostreptococcus, megasphaera, veillonella, eubacterium, bifidobacterium, clostridium, and fusobacterium were included. all strains were susceptible to chloramphenicol, but varied in their susceptibility to penicillin, lincomycin, clindamycin, tetracyclines, and vancomycin. correlatio ... | 1975 | 1137353 |
| microdilution technique for antimicrobial susceptibility testing of anaerobic bacteria. | a microdilution technique using commercially available media and materials was developed and used to determine the minimal inhibitory concentrations (mics) of clindamycin, chloramphenicol, tetracycline, minocycline, ampicillin, carbenicillin, cephalothin, and gentamicin for 101 anaerobic isolates. representative strains of bacteroides, clostridium, fusobacterium, peptococcus, and peptostreptococcus were tested. the use of schaedler broth at ph 7.2, an inoculum of 10(5) to 10(7) colony-forming un ... | 1975 | 1137383 |
| susceptibility of sphaerophorus necrophorus isolated from cattle in the sudan to chemotherapeutic agents. | 1975 | 1139288 | |
| a simple method for rapid identification of sphaerophorus necrophorus isolates. | a hemagglutination inhibition test for the rapid identification of sphaerophorus necrophorus is described. erythrocytes from six species of animals were tested and human cells were found to be the best agglutination indicators. antiserum prepared in rabbits was found to be specific for s. necrophorus hemagglutinins when tested against 20 isolates of s. necrophorus and 117 other bacteria belonging to 22 genera. the possibility of using a hemagglutination inhibition test for the detection of bovin ... | 1975 | 1139415 |
| endotoxin from fusobacterium necrophorum of bovine hepatic abscess origin. | the endotoxic activity of fusobacterium necrophorum bov 5 was investigated. the supernatant (s) fluid and cell wall (cw) preparation, obtained after differential centrifugation of the ruptured cell mass, were lethal for mice. the toxicity of the s fluid was stable during prolonged storage, treatment with formalin, and heating for 15 minutes at 80, 100, and 121 c, but was destroyed by alkaline hydrolysis with 0.25 n naoh. the toxic factor was found in a high molecular weight (mw) fraction after g ... | 1975 | 1147341 |
| effects of minocycline and other antibiotics on fusobacterium necrophorum infections in mice. | several antibiotics were evaluated in model infections produced in mice with each of two strains of fusobacterium necrophorum. in one model, local abscesses occurred at the site of subcutaneous injection; in another intra-abdominal abscesses were produced when the organisms were injected into the peritoneal cavity. treatment with effective antibiotics prevented the formation of abscesses or minimized the size of the lesions. several treatment schedules were used. minocycline was the most active ... | 1975 | 1147577 |
| fusobacterium necrophorum and bacteroides melaninogenicus as etiologic agents of foot rot in cattle. | fusobacterium necrophorum (sphaerophorus necrophorus) and bacteroides melaninogenicus were the predominant bacteria isolated from biopsy specimens of lesions in cattle affected with foot rot. mixed inoculums of the 2 bacteria, applied to the scarified interdigital skin or inoculated intradermally into the interdigital skin of test cattle, induced typical lesions of foot rot. both bacteria were reisolated in large numbers from the induced lesions. | 1975 | 1155832 |
| evaluation of human oral organisms and pathogenic streptococcus for production of iga protease. | iga protease is a proteolytic enzyme found in whole human saliva and in dental plaque that cleaves both secretory and myeloma iga of human origin to yield intact fabalpha and fcalpha fragments. to determine which bacteria are capable of producing this enzyme, we have examined a variety of strains normally found in the human oral cavity and a number of streptococci of known lancefield group serotype. streptococci of groups a, b, c, d, f, g, h, m, and n, streptococcus mutans, streptococcus sanguis ... | 1975 | 1168676 |
| oxygen tolerance of fresh clinical anaerobic bacteria. | the oxygen tolerance and sensitivity of 57 freshly isolated anaerobic bacteria from clinical specimens was studied. all the organisms tolerated 8 h or more of exposure to oxygen in room air. growth of the isolates in increasing oxygen concentrations demonstrated that the 57 isolates varied in oxygen sensitivity from strict to aerotolerant anaerobes. comparison of the oxygen tolerance and sensitivity showed that the most tolerant organisms (best survival after prolonged exposure) included anaerob ... | 1975 | 1176601 |
| delayed post-traumatic subdural empyema. | a case of subdural empyema is reported, treated through a frontal bone flap, with exenteration of the infected frontal sinus at operation, and subdural instillation of antibiotics for 48 hours postoperatively. diagnostic findings are reviewed, and the likelihood of anaerobic infection this case and similar cases discussed. | 1975 | 1177340 |
| comparison of cefoxitin and cephalothin therapy of a mixed bacteroides fragilis and fusobacterius necrophorum infection in mice. | cefoxitin, a beta-lactamase-resistant cephalosporin, was found to be more effective than cephalothin against an experimental mixed infection containing bacteroides fragilis and fusobacterium necrophorum. | 1975 | 1180547 |
| susceptibility of the liver and biliary tract to anaerobic infection in extrahepatic biliary tract obstruction. bacteriological investigations - an experimental study in rabbits. | the influence of common duct occlusion on susceptibility to infection with anaerobic gram-negative rods was investigated in rabbits. intravenous inoculation was performed with three b. fragilis strains isolated from human infections and with a stock culture of fusobacterium mortiferum. liver tissue, gallbladder, bile, and blood were investigated. anaerobic culture procedures were based on the use of a 'glove-box' with an oxygen-free atmosphere and pre-reduced, anaerobically sterilized media. ana ... | 1975 | 1188311 |
| simplified method for antimicrobial susceptibility testing of anaerobic bacteria. | a simple, abbreviated broth dilution test (tube test) utilizing a commercially available medium and inexpensive disposable materials, and which could be performed entirely in room air, was developed and used to test the susceptibility of 100 strains of anaerobic bacteria to clindamycin, chloramphenicol, ampicillin, and tetracycline. results are reported in categories of susceptibility: susceptible to concentrations surpassed in vivo with usual dosage, susceptible to concentrations surpassed in v ... | 1975 | 1190751 |
| "bad breath": presenting manifestation of anaerobic pulmonary infection. | three patients are described in whom a putrid breath odor was the only or fist manifestation of anaerobic infection of the lung. fever, productive cough, and pleuritic pain, common findings in anaerobic pulmonary infection, were not initally present. "bad breath" may be an early due to the presence of anaerobic pulmonary infection. | 1975 | 1203000 |
| antigenic structure of wild clostridium perfringens strain type a and its mutants. | 1975 | 1212625 | |
| immunochemical investigations on sphaerophorus funduliformis endotoxins. | 1975 | 1212626 | |
| [morphological changes of oral fusobacterium caused by antibiotics]. | 1975 | 1240176 | |
| susceptibility of the liver and biliary tract to anaerobic infection in extrahepatic biliary tract obstruction. ii. liver function and morphology of the liver and biliary tract--an experimental study in rabbits. | biliary tract infection with anaerobic bacteria (b. fragilis or fusobacterium mortiferum) was produced in rabbits by common duct ligation (c.d.l.) 3 days prior to intravenous bacterial inoculation. animals were investigated 1, 4 or 7 days after inoculation. histopathological investigations included the liver, the common duct, and the gallbladder, while liver function was evaluated by bilirubin, alkaline phosphatase (ap), and l-alanine aminotransferase (gpt) in serum. rabbits with c.d.l. and bili ... | 1976 | 1251134 |
| anaerobic infections in surgery: clinical review. | anaerobic bacteria are being recognized with increasing frequency as important micro-organisms in surgical infections. clostridium, bacteriodes, fusobacterium, and peptostreptococcus are the clinically prominent pathological anaerobes. all are commensals and, consequently, most anaerobic infections are endogenous in origin. in the colon, anaerobes are 1,000 times more prevalent than aerobes. this has important implications regarding the management of gastrointestinal tract operations and the tre ... | 1976 | 1257897 |
| hyperbaric oxygen exposures for intrahepatic abscesses produced in mice by nonsporeforming anaerobic bacteria. | hyperbaric oxygen exposures were evaluated for treatment of progressive liver abscesses produced by intraperitoneal injection of combined cultures of fusobacterium necrophorum plus either bacteroides fragilis subsp. fragilis or fusobacterium nucleatum in a mouse model. infected control and hyperbaric oxygen-exposed mice were autopsied 5 or 6 weeks after inoculation of bacteria and were assigned numerical pathology scores according to the number and size of abscesses present. seventeen daily 3-h ... | 1976 | 1267430 |
| rosamicin: in vitro activity against anaerobes and comparison with erythromycin. | the in vitro activity of rosamicin was determined against 231 strains of anaerobic bacteria and compared with the activity of erythromycin against the same strains. rosamicin and erythromycin had similar activity against strains of peptostreptococcus and gram-positive nonsporeforming bacilli. rosamicin was somewhat more active against strains of peptococcus, clostridium, and gram-negative anaerobes. all strains of bacteroides fragilis tested were inhibited by 4 mug of rosamicin or less per ml, w ... | 1976 | 1267432 |
| intestinal microflora in rats: isolation and characterization of strictly anaerobic bacteria requiring long-chain fatty acids. | three strains of strictly anaerobic bacteria, isolated from the cecal contents of rats, have strict requirements for long-chain fatty acids. the effect of exogenous fatty acids on the growth and fatty acid composition of the bacteria was examined. biohydrogenation of linoleic acid into octadecenoic acid was observed. these observations suggest that long-chain fatty acids in the intestine are factors in controlling the localization and the population levels of indigenous bacteria in vivo in rats. | 1976 | 1267446 |
| fusobacterium necrophorum infection in mice as a model for the study of liver abscess formation and induction of immunity. | a mouse model is described in which intraperitoneal injection of fusobacterium necrophorum results in chronic liver abscesses. viable bacterial counts from mouse lung, liver, and spleen were obtained after whole organ homogenization. from 2 h to 5 days postchallenge, liver was found to contain more bacteria than lung on a per gram basis. bacterial counts from liver and spleen were about the same during the first 8 h; thereafter liver was found to contain more bacteria. by day 13, though bacteria ... | 1976 | 1270151 |
| [antibacterial and bactericidal activity of tinidazole against anaerobic bacteria comparing with metronidazole (author's transl)]. | antibacterial activity of tinidazole (1-2-(ethylsulfonyl)-2-methyl-5-nitroimidazole) against anaerobic bacteria including peptococcus, peptostreptococcus, eubacterium, propionibacterium, bacteroides and fusobacterium was studied by agar dilution method comparing with metronidazole. in addition to this work, bactericidal effect of tinidazole and metronidazole against p. prevotii, b. fragilis ss. fragilis and f. varium was examined by quantitative culture method after incubation in gam broth conta ... | 1976 | 1271586 |
| experimentally induced foot rot in feedlot cattle fed rations containing organic iodine (ethylenediamine dihydriodide) and urea. | foot rot was experimentally induced in feedlot cattle with a mixed inoculum of fusobacterium necrophorum (sphaerophorus necrophus) and bacteroides melaninogenicus. both bacteria were isolated from the lesions. isolates of f necrophorum from 2 of the lesions were serologically compared, using a passive hemagglutination test with the strain used to induce the lesions. these isolates were serologically similar but not identical, indicating antigenic change had occurred during animal passage. the ad ... | 1976 | 1275334 |
| absolute configuration of 3-hydroxy fatty acids present in lipopolysaccharides from various bacterial groups. | the absolute configuration of 3-hydroxy fatty acids has been studied, which are present in the lipopolysaccharides of the following bacteria: phodopseudomonas gelatinosa, rh. viridis, rhodospirillum tenue, chromobacterium violaceum, pseudomonas aeruginosa, bordetella pertussis, vibrio metchnikovii, vibrio cholerae, salmonella spp., escherichia coli, shigella flexneri, proteus mirabilis, yersinia enterocolitica and fusobacterium nucleatum. the 3-hydroxy acids were liberated by strong alkaline hyd ... | 1976 | 1278168 |
| development and characterization of porphyromonas gingivalis-specific rat t-cell clones. | porphyromonas gingivalis has been implicated as a major pathogen in periodontitis. to determine the role of t cells in the regulation of this disease, a method was developed for the generation and characterization of rat t-cell clones with antigen specificity to p. gingivalis whole cells. the clones studied so far demonstrated a t-helper (th) phenotype w3/13+, w3/25+, ox8- and ox22-. these t-cell clones proliferated in vitro in response to p. gingivalis, but not to other bacteria (prevotella int ... | 1992 | 1281976 |
| putative periodontal pathogens on titanium implants and teeth in experimental gingivitis and periodontitis in beagle dogs. | the microflora around titanium implants and teeth in 4 beagle dogs was analyzed in order to follow the longitudinal development from healthy conditions to experimental gingivitis and periodontitis. a 2-month plaque control program was performed to establish healthy conditions on titanium implants and control teeth (baseline, day 0). subgingival bacterial samples and radiographs were obtained. the plaque control was ceased and all measurements were repeated on day 21 (gingivitis). a new period of ... | 1992 | 1290791 |
| soft-tissue management through effective patient subgingival bacterial control. | 1992 | 1291435 | |
| resistance of anaerobic bacteria to antimicrobial agents in spain. | as a consequence of antibiotic consumption, the entire microbial ecosystem attached to man is evolving towards resistance. in spain, penicillin resistance (mic > 0.5 mg/l) is found in about 10% of peptostreptococcus, clostridium perfringens and eubacterium, and in 50% of veillonella. cefoxitin resistance ( > 2 mg/l) is present in 10 to 20% of peptostreptococcus and clostridium, and in 50% of eubacterium; 21% of bacteroides (fragilis group) strains are resistant to 16 mg/l. a very low rate of imi ... | 1992 | 1295754 |
| beta-lactamase production and susceptibility of us and european anaerobic gram-negative bacilli to beta-lactams and other agents. | the susceptibility of 1,476 us and european strains of anaerobic gram-negative bacilli to amoxicillin, amoxicillin/clavulanate, ticarcillin, ticarcillin/clavulanate, cefoxitin, imipenem and metronidazole was determined. all of the bacteroides fragilis group and 51% of the non-bacteroides fragilis group were beta-lactamase positive. amongst the non-bacteroides fragilis group, beta-lactamase positivity rates were higher for us strains (58%) than for european strains (39%). all strains were suscept ... | 1992 | 1295763 |
| infection and labor. vii. microbial invasion of the amniotic cavity in spontaneous rupture of membranes at term. | the purpose of this study was to determine the frequency, microbiologic characteristics, and clinical significance of microbial invasion of the amniotic cavity in women with premature rupture of membranes at term. | 1992 | 1301006 |
| [roxithromycin in dental infections]. | roxithromicin is a semisynthetic macrolide antibiotic, with similar antibacterial activity to erythromycin. it is characterized by an excellent pharmacokinetic profile and a good tissue penetration. particularly at the dose of 300 mg per day the dental tissue diffusion is extremely good, and this is important to oppose the oral cavity infections. oral cavity infections can be either odontogenic or non odontogenic. odontogenic infections are typically primary and are caused by commensal bacteria ... | 1992 | 1301492 |
| the effect of 3 mouthrinses on plaque and gingivitis development. | the aim of this study was to evaluate the effect of 3 mouthrinses, listerine antiseptic (thymol), peridex (chlorhexidine), perimed (povidone iodine and hydrogen peroxide), and a placebo (water) on the development of dental plaque and gingivitis, when used as the only oral hygiene procedure for 14 days. 71 subjects were entered into a randomized, double-blind study. at the baseline examination, papillary bleeding score (pbs), and plaque index (pi) were registered, after which subjects received su ... | 1992 | 1310096 |
| susceptibility of anaerobic bacteria to pd 131628. | the in vitro activity of pd 131628 against anaerobic cocci, propionibacterium acnes, clostridium perfringens, clostridium difficile, bacteroides fragilis, bacteroides spp. and fusobacteria was determined by the agar dilution method. this activity was compared with that of ciprofloxacin, piperacillin, cefoxitin, imipenem, clindamycin, metronidazole and chloramphenicol. pd 131628, imipenem, clindamycin, metronidazole and chloramphenicol were the most active agents tested. | 1992 | 1314176 |
| microbiology of healthy and diseased periodontal sites in poorly controlled insulin dependent diabetics. | a group of poorly-controlled insulin dependent diabetes mellitus (iddm) patients were examined in a cross-sectional design for total microbial levels, microbial incidence, and the percent levels of selected periodontal microorganisms. these organisms were selected on the basis of prior reports that associated them with either periodontal disease or health. one periodontally-healthy and one periodontally-diseased site were examined in each iddm patient. increased levels of the periodontal pathoge ... | 1992 | 1315389 |
| [quantitative direct gas-liquid chromatography for rapid diagnosis of anaerobic infections]. | quantitative direct gas-liquid chromatography (glc) was performed on 74 specimens of surgical infections and relevant findings were compared with cultural results. in the present study, significant amounts of multiple volatile fatty acids (vfa) and/or succinate were found as markers of anaerobic infections. at least one of the vfa (propionic, isobutyric, butyric, isovaleric or valeric acid) greater than or equal to 0.1 mumol/ml and/or succinate greater than or equal to 0.3 mumol/ml was strong ev ... | 1992 | 1315609 |
| in vitro activities of three of the newer quinolones against anaerobic bacteria. | the antimicrobial activities of three new quinolone compounds, sparfloxacin, temafloxacin, and win 57273, against anaerobic bacteria were determined in three separate studies. the wadsworth agar dilution technique using brucella-laked blood agar was used throughout. the activities of other antimicrobial agents, including ciprofloxacin, imipenem, chloramphenicol, metronidazole, cefotetan, cefoxitin, and amoxicillin-clavulanic acid, were also determined. the breakpoints of the new quinolones were ... | 1992 | 1317149 |
| the use of dna probes to examine the distribution of subgingival species in subjects with different levels of periodontal destruction. | the present investigation examined the distribution of 14 subgingival species at a total of 2299 sites in 90 subjects with different levels of periodontal destruction. subgingival plaque samples taken from the mesial aspect of each tooth were anaerobically dispersed, diluted and plated on non selective media. after anaerobic incubation, colonies were lifted to nylon filters and specific species detected using digoxygenin-labeled whole chromosomal dna probes. the mean total viable count for all s ... | 1992 | 1318331 |
| subgingival temperature (iii). relation to microbial counts. | the present investigation examined the relationship of selected bacterial species and subgingival temperature. 35 subjects were measured at 6 sites per tooth for clinical parameters and subgingival temperature. measurements were repeated for 21 subjects at 2 month intervals providing a total of 66 subjects visits. at each visit, subgingival plaque samples were taken from the mesial aspect of each tooth and anaerobically dispersed, diluted and plated on non-selective media. after anaerobic incuba ... | 1992 | 1321846 |
| synergistic effect of pyrophosphate and sodium dodecyl sulfate on periodontal pathogens. | our previous studies have shown that pyrophosphate (ppi), the anticalculus component of tartar-control dentifrices, inhibits the growth of organisms associated with coronal and root surface caries. the purposes of this investigation were to: 1) determine if periodontal pathogens are similarly susceptible to the growth-inhibitory properties of ppi; and 2) determine if combinations of pyrophosphate-sodium dodecyl sulfate (ppi-sds) inhibit growth synergistically. porphyromonas gingivalis, actinobac ... | 1992 | 1324304 |
| role of porphyromonas gingivalis 40-kda outer membrane protein in the aggregation of p. gingivalis vesicles and actinomyces viscosus. | porphyromonas gingivalis, an important pathogen in periodontitis, produces extracellular vesicles that aggregate with actinomyces viscosus cells. a 40-kda outer membrane protein (omp)-coding gene from p. gingivalis was cloned and the protein was found to be localized in these vesicles. the recombinant 40-kda omp did not show aggregation activity. however, affinity-purified antibody against the recombinant protein significantly inhibited aggregation of p. gingivalis vesicles with a. viscosus cell ... | 1992 | 1329700 |
| effect of clavulanic acid, sulbactam and tazobactam on three different beta-lactamases from bacteroides uniformis, clostridium butyricum and fusobacterium nucleatum. | the effect of three beta-lactamase inhibitors, clavulanic acid, sulbactam and tazobactam used in clinical practice were compared for their activity against purified beta-lactamases from bacteroides uniformis, clostridium butyricum and fusobacterium nucleatum. the enzymes from b. uniformis and c. butyricum were produced in fermenters under controlled growth conditions and the enzyme from f. nucleatum was produced in batch cultures. purification of the beta-lactamases was achieved by anion-exchang ... | 1992 | 1331018 |
| comparative in-vitro activity of azithromycin, macrolides (erythromycin, clarithromycin and spiramycin) and streptogramin rp 59500 against oral organisms. | the in-vitro activities of azithromycin, clarithromycin, spiramycin and rp 59500 were compared with erythromycin against a wide range of oral organisms which have been implicated in oral infections and/or endocarditis (clindamycin was included for oral streptococci). all compounds tested showed good activity against many of these organisms, although some variation was observed with different species. clarithromycin was the most active of the antibiotics tested against gram-positive anaerobes, in ... | 1992 | 1331019 |
| correlation of haemagglutination activity with trypsin-like protease activity of porphyromonas gingivalis. | porphyromonas gingivalis is a gram-negative anaerobic bacterium associated with various forms of periodontal disease. several characteristics of p. gingivalis are thought to contribute to its pathogenicity; these include haemagglutination and trypsin-like protease activity. previous studies suggest an association between haemagglutination and trypsin-like protease activity of p. gingivalis. to investigate this, two complementary quantitative experimental approaches were taken. five independent m ... | 1992 | 1332663 |
| sensitization of oral bacteria in biofilms to killing by light from a low-power laser. | biofilms of streptococcus sanguis, porphyromonas gingivalis, fusobacterium nucleatum and actinobacillus actinomycetemcomitans were prepared on the surfaces of agar plates and a number of compounds were screened for their ability to sensitize bacteria in these biofilms to killing by light from a 7.3 mw helium/neon (he/ne) laser. toluidine blue o and methylene blue enabled detectable killing of all four target organisms after exposure to he/ne light for 30 s. aluminium disulphonated phthalocyanine ... | 1992 | 1334649 |
| bacterial concentration fluorescence immunoassay (bcfia) for the detection of periodontopathogens in plaque. | a bacterial concentration fluorescence immunoassay (bcfia) was developed to rapidly detect periodontopathic bacteria in human plaque samples. the bcfia utilized fluorescent-tagged monoclonal antibodies (mabs) directed against the lipopolysaccharide of selected gram-negative bacteria. microorganisms identified in plaque using the bcfia included actinobacillus actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, and fusobacterium nucleatum. the immunoassay procedure involved com ... | 1992 | 1336047 |
| dna probe and enzyme analysis in periodontal diagnostics. | recent research in periodontology has indicated that a finite number of bacterial species are associated with periodontal disease. this has generated the hypothesis that periodontal disease is essentially an infection due to one or more of the putative periodontopathogens; i.e., the specific plaque hypothesis (sph). this microbial specificity paradigm has already changed the way researchers and some clinicians view periodontal disease. the clinician must heed several cautions signs, however, if ... | 1992 | 1336048 |
| antibacterial efficacy of root canal medicaments. | the antibacterial efficacy of four endodontic medicaments was studied in vitro. calcium hydroxide (calacept), camphorated parachlorophenol (cpcp), cresophene, and 2% iodine-potassium iodide (iki) were tested against four anaerobic microorganisms, streptococcus mutans, peptostreptococcus anaerobius, porphyromonus gingivalis and fusobacterium nucleatum, for 10 or 15 min. iki was effective only against f. nucleatum and p. gingivalis, and the others were effective against all four microorganisms. | 1992 | 1337555 |
| effect of beta-lactamase inhibitors on beta-lactamases from anaerobic bacteria. | three beta-lactamase inhibitors in clinical use--clavulanic acid, sulbactam and tazobactam--were investigated for their activity on beta-lactamases from bacteroides uniformis, clostridium butyricum and fusobacterium nucleatum. purification of the beta-lactamases was carried out by anion-exchange chromatography, gel filtration and fplc. the inactivation of beta-lactamase activity was determined spectrophotometrically with nitrocefin as substrate. various concentrations of the inhibitors were prei ... | 1992 | 1338315 |
| summer mastitis in heifers: studies on the seasonal occurrence of actinomyces pyogenes, peptostreptococcus indolicus and bacteroidaceae in clinically healthy cattle in denmark. | with the aim of investigating the seasonal occurrence of actinomyces pyogenes, peptostreptococcus indolicus, bacteroides melaninogenicus ss. levii and fusobacterium necrophorum, and thus the potential for development of summer mastitis, clinically healthy danish holstein-friesian heifers due to calve in the autumn were sampled from the teat tip, the conjunctiva and the oral cavity at 2-6 week intervals from 1979 to 1981. the overall isolation rates of f. necrophorum, p. indolicus and b. melanino ... | 1992 | 1348381 |
| immunoglobulins in milk from cows immunized with oral strains of actinomyces, prevotella, porphyromonas, and fusobacterium. | immunization of pregnant cows with bacteria leads to the presence of high concentrations of specific antibodies in colostrum and milk. a total of 14 cows was immunized with single strains of heat-killed oral bacteria or pools of strains of actinomyces, porphyromonas, prevotella, and fusobacterium. two cows were treated with adjuvant alone. the mean percentages of igg1, igg2, igm, and iga in all of the milks were 83.8, 3.8, 9.3, and 3.1, respectively. elisa and whole cell agglutination assays dem ... | 1992 | 1354674 |