Publications

developing audit criteria for outpatient care based on throat culture findings.		2000	97594
[quantitative method of assessing the virulence of mycobacterium tuberculosis in an experiment on guinea pigs].		1978	97664
inhibition of dual ir gene-controlled t-lymphocyte proliferative response to poly (glu56lys35phe9)n with anti-ia antisera directed against products of either i-a or i-c subregion.	previous studies have demonstrated that both the antibody and t-lymphocyte proliferative immune responses to poly(glu53lys36phe11)n (glphi) are under the control of two major histocompatibility-linked immune response (ir) genes. one gene, termed ir-gl phi-alpha, has been mapped to the i-c or i-e subregion of the major histocompatibility complex, while the other, termed ir-gl phi-beta, has been mapped to the i-a subregion. in this paper we examine the effect of anti-i-region-associated (ia) antis ...	2000	97668
urinary excretion of vanyl-mandelic acid correlated with ischemic heart disease.	the concentration of vanyl-mandelic acid is analysed in the urine collected within 24 hours from normal subjects, from those with painful ischemic cardiopathy, infarction and post-infarction sequelae. statistically significant results have been obtained only in infarction patients. the study of the concentration of vanyl-mandelic acid by age decades points to the increase of average values throughout life.	2000	97685
the standardization of blood bank antisera with the groupamatic 360 c system.		2000	97752
[quantitative measurement of red cell antigens with groupamatic].	groupamatic 360 can be adapted to the quantitative measurement of erythrocyte agglutination reactions. here the authors give the necessary conditions to obtain the best sensitivity and the best reproductibility. they have considered globular suspensions, incubation of the erythrocyte antiserums mixtures, centrifugation, agitation, photometric measurement. as concerns the quantitative technique, we used the average peripheral measurement obtained in the twleve cuvettes of the same selected disc s ...	2000	97753
isolation care of infection-prone burn patients.	an experimental and clinical study of spread of colonisation between burn patients, and their susceptibility to infection, was performed. burn patients' polymorphonuclear neutrophil granulocytes (pmn) functioned poorly, particularly during the second week after injury which coincided with maximum growth of bacteria in the burn wound. patients with large burns often dispersed s. aureus and ps. aeruginosa but also beta-hemolytic streptococcus to the air of their rooms. airborne transfer of these b ...	1978	97776
alcoholic liver disease, new aspects of an old problem.	in the therapy of alcoholic liver disease, two recent trends deserve consideration, one is the role of immunologic mechanisms and the other is the effect of nutrition. in various double blind studies no improved survival of corticosteroid treated patients with alcoholic hepatitis has been found. intravenous hyperalimentation with amino acid solution combined with peroral feeding seemed, however, to have a beneficial effect in alcoholic hepatitis.	2000	97777
localization of primate calls by old world monkeys.	monkeys (macaca) were trained by operant conditioning techniques to report the minimum detectable change in location of a sound in space, and were tested with a series of recorded coo or clear call vocalizations. acuity of localization varied from approximately 4 degrees to 15 degrees and was a function of the magnitude of the change in pitch (frequency modulation) of the different clear calls.	1978	97785
what is right with american medicine.		2000	97798
alterations of intercellular junctions in acinic cell carcinoma of the canine pancreas.	intercellular junctions in spontaneous canine pancreatic acinic cell adenocarcinomas were compared to those in control canine pancreas. the neoplastic cells displayed proliferation and fragmentation of tight junctions and reduction in size and number of gap junctions. marked decrease in desmosomal density was observed only in the poorly differentiated carcinoma. in the well differentiated carcinomas a few of the desmosomes were characteristic of those found in squamous cells. no quantatitive or ...	1978	97855
electron microscopic morphometric analysis of human t and b peripheral blood lymphocytes.	using the system of morphometric analysis described in this paper, human peripheral blood t and b lymphocytes, labeled with specific surface markers, can be compared on different analytical levels. they show differences in their surface and the eccentricity of cells, in the relative surfaces occupied by peripheral and central condensed chromatin, in the average surface of the central chromatin clumps and in the number of perichromatin granules per nuclear surface. the morphometric analysis revea ...	1978	97857
identification of bacteria in the bile by duodenal aspiration.		2001	97868
a human studying the sensing of chemicals by bacteria.	a new frame of reference, which in its fundamental structuring differs radically from the structuring of the familiar western indo-european viewpoints (logical, mathematical, scientific, philosophical, etc.), already exists. recently, by the strategem of systematically disallowing a previously unnoticed untenable assumption encoded in the traditional western symbolic logics, set theories, etc., in particular and in the western 'world-view' in general, this frame of reference has generated its ow ...	1978	97887
manometric study of the lower oesophageal sphincter in adult nigerians in relation to the rarity of hiatus hernia and symptomatic gastro-oesophageal reflux.		2001	97947
benign pneumoperitoneum following median sternotomy incision.	because of the close anatomic relationship of the pericardium, diaphragm, and peritoneal cavity, a benign pneumoperitoneum may occur following median sternotomy incision and cardiac surgery. the pneumoperitoneum results from inadvertent opening of the peritoneal cavity during the initial surgical incision or during the subsequent cardiac surgery. it is generally of no significance to the patient, although it must be distinguished from pneumoperitoneum occuring secondary to intraabdominal patholo ...	2001	98006
pleural herniation in respiratory distress syndrome.		2001	98029
the reimbursement riddle: part 1. where do all the health dollars go?		2001	98034
menstruation in intraocular endometrial transplants in the rhesus monkey.		1978	98044
effects of various divalent cations on the survival of neisseria gonorrhoeae in liquid media.	the effect of various concentrations of divalent cations on survival of gonococci in liquid medium was studied. the growth of neisseria gonorrhoeae was inhibited by manganous chloride in concentrations above 1 x 10(-5)mol/l while the growth of control organisms such as neisseria meningitidis and escherichia coli was not inhibited by the same salt even at 1 x 10(-2)mol/l. copper sulphate, cobaltous nitrate, nickel chloride, and zinc sulphate also had deleterious effects on gonococci. magnesium ch ...	1978	98204
trh-like immunoreactivity in urine, serum and extrahypothalamic brain: non-identity with synthetic pyroglu-hist-pro-nh2 (trh).	trh-like immunoreactive substances obtained from several areas of rat brain and from human serum and urine were chromatographically separated by tlc and the resulting immunoreactive 'elution profiles' compared with that obtained for pyroglu-hist-pro-nh2 (trh). for hypothalamus and septal-preoptic samples trh was present, but represented less than 100% of the immunoreactive substances. for cortex, amygdala, brain stem, serum and urine, no trh was detectable in the immunoreactive substances from t ...	1978	98209
cholestatic jaundice during total parenteral nutrition.		2001	98226
[investigations of the incidence of neisseria gonorrhoeae on the pharyngeal mucosa (author's transl)].		1978	98235
a sensitive procedure for the diagnosis of n-acetyl-galactosamine-6-sulfate sulfatase deficiency in classical morquio's disease.	the trisaccharide 6-sulfo-n-acetylgalactosamine-glucuronic acid-6-sulfo-n-acetyl-[1-3h]galactosaminitol was used as a substrate for the determination of n-acetylgalactosamine-6-sulfate sulfatase activity. the amount of liberated sulfate was measured indirectly by separating monosulfated reaction products from the substrate on dowex 1 x 2 microcolumns in a simple two step procedure. fibroblast homogenates from patients with various genotypes, except classical morquio's disease, released 410 +/- 9 ...	2001	98244
effect of a lipid load on blood and urinary carnitine in man.	blood and urine carnitine contents have been determined in patients before and after a lipid load and in patients on haemodialysis. oral and intravenous lipid administration significantly depressed blood carnitine content and after 500 ml intravenous intralipid urinary carnitine excretion fell by 43%. blood carnitine was reduced by 50% by haemodialysis and returned to the pre-dialysis value within 20 h in 5 out of 8 patients. it is concluded that the blood carnitine level is normally controlled ...	1978	98245
leukaemia-associated antigens in man.		1978	98250
the two-dimensional fractionation of drosophila dna.		2001	98259
the gene-size dna molecules in oxytricha.		2001	98283
external separation, internal ligation and injection in circumferential mixed hemorrhoids. analysis of 202 cases.		2001	98305
vasodilation, fibrinolysis, and thrombolysis with intraarterial infusion of urokinase in the canine superior mesenteric artery.	urokinase, the plasminogen activator from human urine, produces a dose-dependent increase in blood flow in the canine superior mesenteric artery when injected intraarterially at doses from 10(-1) to 10(3) units kg-1. this vasodilation persists despite blockade of beta-adrenergic and histamine h1 and h2 receptors as well as inhibition of plasminogen activation, suggesting that these mechanisms are not involved. infusion of urokinase at 10(2) cta (committee on thrombolytic agents) units kg-1 min-1 ...	1978	98390
[endothelial and blood interaction in haemostasis, thrombosis and atherogenesis].		2001	98396
the level of manganese in liver, spleen and blood by ultrasonic treatment.		1977	98415
[clinical, parasitological and serological investigations in sarcosporidiosis (sarcocystis suihominis) of man (author's transl)].	eight medical students ate for a test raw meat from a pig experimentally infected with sporocysts of sarcocystis suihominis. the meat had been officially controlled before and was found free of trichinella and qualified for consumption. 6 to 24 hours after the meal all persons suffered from acute clinical symptoms, above all diarrhoea and vomiting, coldness and sweating which decreased, however, within 12 to 24 hours. clinical-chemical investigations made during this time suggested an acute infe ...	1978	98426
dimethyl benz (a) anthracene-radiation synergism in the induction of leukemia in mice: biochemical analysis of leukemic bone marrow & blast cells.		2001	98428
[comparative nutrition studies with 4 l-amino acid solutions in 25 metabolically healthy adults under conditions of parenteral feeding].		2000	98450
angiolithiasis in the parotid gland.	angiolithiasis in salivary glands is a very rare finding, and the knowledge of the morphology and histogenesis of these stone formations is therefore limited. six small angioliths from the left parotid gland of a 19-year-old girl were examined histologically, microradiographically and diffractometrically. the angiolithiasis developed from a regressed hemangioma which had been observed since the patient was 3--4 years old. the angioliths, which were encapsulated, exhibited in some areas diffuse l ...	2001	98457
syndrome of multiple mucosal neurofibromas, pheochromocytoma and medullary thryoid carcinoma. report of a case.	the present article reports a case of multiple endocrine neoplasia (men) syndrome, type iib, including the following components: pheochromocytoma, medullary thyroid carcinoma, hyperplastic corneal nerves and multiple mucosal oral and ocular neurofibromas. the patients, a 35-year-old male also exhibited a series of other pertinent findings, i.e. thickened eyelids, marfanoid habitus and widened mandibular canal and mental foramina. in the discussion the clinical and histopathologic characteristics ...	2001	98459
are baccalaureate level community he specialists an answer to the labor shortage?		2001	98510
altered mrna metabolism in ribonuclease iii-deficient strains of escherichia coli.	the metabolism of mrna from the lactose (lac) operon of escherichia coli has been studied in ribonuclease (rnase) iii-deficient strains (rnc-105). the induction lag for beta-galactosidase from the first gene was twice as long, and enzyme synthesis was reduced 10-fold in one such mutant compared with its isogenic rnc+ sister; in the original mutant strain ab301-105, synthesis of beta-galactosidase was not even detectable, although transduction analysis revealed the presence of a normal lac operon ...	1978	98520
use of glutaraldehyde and formaldehyde to process tissue heart valves.		2001	98522
evolution of immunoglobulin subclasses. primary structure of a murine myeloma gamma1 chain.	the amino acid sequences of the first six cnbr fragments (303 residues) of mopc 21 heavy chain have been determined, using conventional techniques. this completes the determination of the covalent structure of mopc 21 immunoglobulin (igg1, k). mopc 21 gamma1 chain is a unique sequence of 440 amino acid residues. the variable region is homologous with human vhiii sequences. a comparison of the constant region with homologous sequences shows that mouse gamma1 and gamma2 proteins differ much more t ...	1978	98524
immunization with dextransucrases, levansucrases, and glycosidic hydrolases from oral streptococci. ii. immunization with glucosyltransferases, fructosyltransferases, and glycosidic hydrolases from oral streptococci in monkeys.	the feasibility of immunizing monkeys with enzymes from oral streptococci in an attempt to reduce dental caries was investigated. forty rhesus monkeys, macaca mulatta, were used. cariogenic streptococci, s mutans, were implanted into all the monkeys' mouths. there was no pathological effect resulting from immunization. of the 40 animals, 30 retained the implanted flora throughout the experiment; the remaining 10 were reimplanted until the streptococci remained. in six months, gross carious lesio ...	1977	98540
selective habitation of bacteria on "intermediate soft" keratin surfaces of the rat tongue.	scanning and light microscopy reveals a selective and restrictive pattern of indigenous bacterial colonization on the tongue of rats which is accounted for by the preferred attachment of bacteria to an "intermediate soft" keratin substrate. total intravenous feeding of rats for 10 days did not alter this colonization pattern indicating that oral intake of food is not responsible for maintenance of this pattern.	1978	98542
visual-field displacements in human beings evoked by accoustical transients.	sixty-two of 133 subjects reported visual-field displacements when they were exposed to intense (125 db spl) repetitive audiofrequency transients. this phenomenon was investigated in three experiments. frequency (100-5000 hz) was varied in experiment i; repetition rate (0.5/s--6.0/s) was varied in experiment ii; acoustical transient onset/offset time (0.2--25 ms) was examined in experiment iii. the results of these three experiments indicated that the largest proportion of displacement reports a ...	1978	98550
evidence that bovine conglutinin reacts with an early product of c3b degradation, and an improved conglutination assay.	when eac43b were treated with heated serum in edta, reactivity with bovine conglutinin appeared rapidly, even at 0 degrees c, and almost simultaneously with the loss of c3b rosetting capacity. at the time conglutinability first appeared, there was no detectable decrease in i-a or hemolytic c3 activity, and no detectable c3 antigen release from the cells. with prolonged exposure to heated serum in edta, i-a (immune adherence) and hemolytic c3 activity were lost. if this exposure was at 37 degrees ...	1978	98586
characterization and genetic control of the immune response to synthetic polypeptide antigens of defined geometry.	both humoral and cell-mediated immune responses to the synthetic helical hapten-carrier conjugate poly-glu-tyr-lys(tnp)-(glu-tyr-ala)5 were found to be linked to the major histocompatibility locus in mice and guinea pigs. the responder mouse strains (h-2d haplotype) showed a primary igm response with an igg component appearing after the secondary immunization. the antibody response was accompanied by a positive dth reaction in responder strains. nonresponder mice (h-2b or h-2k haplotypes) showed ...	1978	98587
induction of hard tissue into pulpless open-apex teeth using collagen-calcium phosphate gel.		2001	98608
parietal association cortex in the primate: sensory mechanisms and behavioral modulations.		2001	98614
gonorrhea detection in posthysterectomy patients.	a retrospective study of women examined at the venereal disease clinic after hysterectomy was made to determine which culture site was most likely to show anogenital neisseria gonorrhoeae infection when the cervix was absent. seventeen of 104 such patients were culture positive for n gonorrhoeae. rates of positivity for our culture sites were as follows: urethral, 17/17 (100%); vaginal, 7/17 (41%); and rectal, 2/17 (12%).	1978	98647
[shock lung (review of foreign literature)].		1978	98662
the ovarian plantiff.		2001	98681
immunofluorescent techniques in the analysis of chromosomal proteins.		2001	98686
freedom, the will-o'-the-wisp.		1978	98690
localised insertion of new cell wall in bacillus subtilis.		1978	98715
electron-microscopic identification of axonal initial segments belonging to interneurons in the dorsal lateral geniculate nucleus of the monkey.		1978	98733
posttraumatic epilepsy and acute intermittent porphyria: effects of phenytoin, carbamazepine, and clonazepam.	a patient with uncontrolled posttraumatic epilepsy and acute intermittent prophyria was subjected to successive therapeutic trials with phenytoin, carbamazepine, and clonazepam, while eating an adequate diet. both phenytoin and carbamazepine treatments caused significant increases in porphobilinogen excretion and appeared to induce acute porphyric attacks. in contrast, treatment with clonazepam under rigid dietary control for 10 days caused no increase in porphilbinogen excretion. during the sub ...	2001	98734
[diagnosis and nosological classification of micromelic nanism in the newborn infant].		2001	98751
effects of d-amphetamine on temporal and spatial discrimination in rats.	rats were trained to lever-press for food reinforcers on a multiple schedule that had a fixed-interval (fi) and a differential reinforcement of low rate (drl) component. illumination of a stimulus light above the right-hand lever indicated that responses on this lever would be reinforced according to a fi 60-s schedule while responses on the left-hand lever were without programmed consequences. however, when the light above the left-hand lever was illuminated only responses on this lever were re ...	1978	98789
can cigarette size and nicotine content influence smoking and puffing rates?	the stimuli controlling the rate at which people smoke cigarettes have not been clearly defined. on the hypothesis that smoking is basically nicotine-seeking behavior, nicotine available to the subject was experimentally manipulated through controlling cigarette size and nicotine content. in experiment i, subjects given their won cigarettes in whole, half, quarter, and eighth lengths, increased the number of cigarettes smoked and number of puffs to compensate for reductions in size. satisfaction ...	2001	98802
an alternate approach to hospital cost control: the rochester project.	the rapid escalation in health care costs has demonstrated a need to control costs in general and hospital costs in particular. in new york state, efforts at control have followed one of several paths, including reduction of medicaid program expenditures, elimination of hospital beds, and prospective reimbursement of hospital costs. although some success has been achieved in each of these areas, hospital costs containment has not been as successful as had been hoped. a new project called maxicap ...	2001	98805
normal values for free light chains in serum different age groups.	the concentration of free light chains from the immunoglobulins was measured in twelve paired sera from mothers and newborns and from 149 sera from normal individuals in various age groups. variations in concentration during life are correlated to the variations in the concentration of 'regular' immunoglobulins. a concentration of light chains in cord blood of 35% of mean normal adult level (mna) together with a rapid passage of light chains across the placenta is interpreted as indicating catab ...	2001	98826
clinical significance of precipitating anti-rifampicin antibodies.		2001	98841
regulative interactions between cells from different imaginal disks of drosophila melanogaster.	the regulative behavior of cells from the imaginal wing disk of drosophila melanogaster can be modified by interaction with cells from different disk types. both thoracic and nonthoracic disks are able to interact, but there are major differences in the effectiveness of interaction. the finding lends experimental support to the idea that cells in different fields within the same organism use the same mechanism for specifying positional information. a similar conclusion has been reached by wilcox ...	2001	98843
experimental spinal cord trauma, ii: blood flow, tissue oxygen, evoked potentials in both paretic and plegic monkeys.	graded clinical motor deficits were produced in a series of rhesus monkeys subjected to experimental spinal cord trauma from a variety of impact loads. an argon washout technique was used to measure spinal cord blood flow; tissue oxygen carbon dioxide, and somatosensory evoked potentials (seps) were also monitored. each animal received a clinical grade and, after a week of study, the spinal cords were removed for histopathological grading. blood flow in paraplegic animals was significantly decre ...	1978	98856
[experiments to reproduce paratyphoid in pigs of different ages].		1978	98900
quantitation of particles in the freeze-fractured nuclear membrane after renal ischemia.	changes in the number and sizes of membrane-associated particles have been quantitated in the protoplasmic (p) and exoplasmic (e) fracture faces of the outer membrane of nuclei isolated from the inner cortex following renal ischemia and reflow in the rat. no changes were observed in the inner nuclear membrane. after 20-min ischemia, the number of particles in both fracture faces decreased. with reflow, the total number of particles decreased after both 20- and 60-min ischemia. the partition coef ...	1978	98907
hairy cell leukemia: a clinical, immunological and ultrastructural study. new data for the origin of the hairy cell.	seven patients presenting with the characteristic clinical and laboratory findings of hcl were investigated mainly in order to find the origin of the hc with histochemical, electron microscopic and immunologic techniques. the results we obtained are somewhat contradictory, as in the recent literature, if the hc's are to the considered as being exclusively of lymphocytic or monocytic origin. the data however indicate that hcl is not of one cell type but two. one of these cells has characteristics ...	1998	98909
[some aspects relating to the aflatoxin generation during the self-heating of cereals].	in a stored batch of grain which was already affected by mould-formation tests were carried out with the known aflatoxin producer aspergillus flavus. a significantly lower aflatoxin production ensued if the mould growth was not connected with self-heating of the stored product. however, in conformity with increasing mould formation the germinating power was adversely affected and the significant signs (fatty acid number, reductive and none-reductive sugars) were influenced in the grain, irreleve ...	1978	98933
[measurement of the variations of cytoplasmic and nuclear volumes of the absorbing cells of the digestive tube according to the nutritional conditions, in the larva of the common toad (bufo bufo l.)].		1978	98945
differential diagnosis of pelvic masses by gray scale sonography.	an approach to the sonographic differential diagnosis of pelvic masses based on their size, location, internal consistency, and definition of borders is presented. diagnostic schemes were derived from correlating the sonographic features with histomorphology in 170 surgically proven pelvic masses. besides separating pelvic masses into the conventional categories of cystic, complex, and solid, gray scale sonographic features of a pelvic mass can be used to subcategorize these masses into a more u ...	2000	98992
biliary duct ultrasound.		2000	99016
jaundice and breast-feeding among alaskan eskimo newborns.	the course, incidence, and severity of neonatal jaundice was studied in 95 alaskan eskimo infants. breast-fed infants had higher bilirubin concentrations than bottle-fed babies. both groups experienced high bilirubin levels, similar to those previously reported in navajo and oriental infants but greater than those observed in whites and blacks. a marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences ...	1978	99026
long-term outpatient vasodilator therapy of congestive heart failure. consideration of agents at rest and during exercise.	increased left ventricular filling pressure and reduced cardiac output are two major hemodynamic deficits in pump failure. in patients with chronic heart failure, consequences of these hemodynamic deficits and diminished cardiac reserve are manifested initially during stress and eventually at rest. the purpose of therapeutic interventions include reduction of ventricular filling pressure increase in cardiac output and improvement in cardiac reserve. to achieve these goals, the hemodynamic effect ...	2001	99031
interferon inducing activity of polyinosinic acid.	although poly(i) is generally considered to be inactive as an interferon inducer, we have found several authentic poly(i) preparations to be effective inducers. their interferon inducing ability varied considerably from one cell system to another. in human diploid fibroblasts, primed with interferon and superinduced by cycloheximide and actinomycin d, all active poly(i) samples proved nearly as effective in inducing interferon as poly(i).poly(c). in primary rabbit kidney cell cultures, the activ ...	1978	99486
natural distribution of squirrel monkey retrovirus proviral sequences in primate dnas.	3h-labelled 70s rna of squirrel monkey retrovirus (smrv) hybridized to a high degree (greater than 52%) to the dna of various tissues of two squirrel monkeys. hybridization of the same probe to dnas of other primates including new world monkeys (woolly monkey, capuchin, owl monkey), old world monkeys (rhesus, african green), apes (gibbon, chimpanzee), and human (a204 cells infected with mpmv) revealed no significant hybridization. analysis of the kinetics of hybridization indicated that smrv pro ...	1978	99487
development of leucocytozoon caulleryi in chick embryos infected by biting of culicoides arakawae through shell membrane.	chick embryos were infected with leucocytozoon caulleryi by biting of the midge, culicoides arakawae, through the shell membrane. schizonts of l. caulleryi were detected in the chorioallantoic membrane and most of the internal organs of embryos and of chicks after hatching. the development of schizonts was slower in embryos than in chickens. soluble antigens of l. caulleryi were demonstrated by the precipitation test in the allantoic fluid and blood from the embryos and chicks. no erythrocytic s ...	1978	99671
immunochemical and clinical characteristic of series of 516 paraproteinemic patients.	a series of 516 cases of paraproteinemia was analysed. according to the class of paraprotein, there were 336 cases of paraprotein igg (65.1%), 101 paraprotein iga (19.6%), 53 paraprotein igm (10.3%) and 1 case of paraprotein igd (0.2%); only light chains were found in 15 cases (2.9%) and doubled paraproteins in 10 cases (1.9%). the average age of the series was 64.2 years. clinically, there were 315 cases of myeloma, 24 cases of waldenström's macroglobulinemia, 126 cases of facultative paraprote ...	2001	99675
serological, immunochemical and immuoncytological properties of granulocyte antibodies.	the immunochemical characteristics of granulocyte allo- and autoantibodies can easily be studied with indirect immunofluorescence techniques. the correlation of these properties with the serological behavior of the antibodies and the clinical condition in which they were found was studied. the investigations included the determination of immunoglobulin class, subclass, light-chain composition, as well as optimal temperature of activity. complement fixation in vitro was also investigated. strikin ...	2001	99875
how much will u.s. medicine change in the decade ahead?	during the past 12 years health care services have been increasingly used by low-income families, largely as a consequence of infusion of more funds into the health care system. the number of persons employed in health-care has gone up along with an expanded governmental role. present governmental concerns are focused on cost and the relation of public attitudes to needs for, and costs of, a system of national health insurance. in the near future, medical services are not likely to be expanded, ...	2001	100033
[cannabis].	cannabis produces a resin, the psychotropic effects of which are known since the high antiquity. it induces euphoria, a feeling of pleasant dreaminess. nevertheless, psychiatric disturbances such as psychomotor deficiency states or acute oniroïd states were described in heavy users countries. these psychiatric disorders put the accent on the starting or catalysing role of cannabis on the premorbid personality. the experimental studies of cannabis on the premorbid personality. the experimental st ...	1978	100034
uk-18892, a new aminoglycoside: an in vitro study.	uk-18892 is a new aminoglycoside antibiotic, a derivative of kanamycin a structurally related to amikacin. it was found to be active against a wide range of pathogenic bacteria, including many gentamicin-resistant strains. the spectrum and degree of activity of uk-18892 were similar to those of amikacin, and differences were relatively minor. uk-18892 was about twice as active as amikacin against gentamicin-susceptible strains of pseudomonas aeruginosa. both amikacin and uk-18892 were equally ac ...	1978	100050
cooperative binding of mn2+ and non-cooperative binding of mg2+ to beta-galactosidase (e. coli).		1978	100107
a rapid and convenient method for purification and isolation of chlorophyll-a from porphyra yezoensis.		1978	100111
experimental criteria for evaluating prostaglandin biosynthesis and intrinsic function.		2001	100118
beta-lactam antibiotics. ii. structure-activity relationships of 6-[alpha-(alpha'-ureido-acylamino) acylamino] penicillanic acids.	the influence on the structure-activity relationships (s.a.r.) of the stereochemistry and various alkyl, aryl, aralkyl and heterocyclic substituents at the two chiral centres in the dipeptide side-chain of a new series of penicillins was examined. in many cases the effects of these changes had a pronounced influence on the degree of activity against gram-positive and especially gram-negative bacteria. several compounds indicated that the size, shape and spatial disposition of a substituent were ...	1978	101499
microbial oxidation of methane and methanol: isolation of methane-utilizing bacteria and characterization of a facultative methane-utilizing isolate.	a methane-utilizing organism capable of growth both on methane and on more complex organic substrates as a sole source of carbon and energy, has been isolated and studied in detail. suspensions of methane-grown cells of this organism oxidized c-1 compounds (methane, methanol, formaldehyde, formate); hydrocarbons (ethane, propane); primary alcohols (ethanol, propanol); primary aldehydes (acetaldehyde, propionaldehyde); alkenes (ethylene, propylene); dimethylether; and organic acids (acetate, mala ...	2000	101517
purification and properties of a bacillus subtilis endonuclease specific for apurinic sites in dna.	an endonuclease which hydrolyzes depurinated dna has been purified from extracts of bacillus subtilis cells. the endonuclease is a monomeric protein and has a molecular weight of around 56,000. the enzyme is specific for apurinic sites in double-stranded dna, has a ph optimum at 8.0, and is slightly stimulated with 50 mm nacl but completely inhibited with 500 mm nacl. it requires no divalent cations and is insensitive to edta; it has no associated exonuclease. these properties are very similar t ...	1978	101548
isolation of staphylococcus aureus from sputum in cystic fibrosis.	the success in the isolation of staphylococcus aureus of different methods of sputum processing was investigated in 60 specimens collected from 14 patients with cystic fibrosis during a seven-month period. fifty specimens (83%) from 11 patients yielded staph. aureus by one or more methods. direct plating of purulent portions of sputum on to media designed for general use in respiratory infections gave unsatisfactory results (35% yield of staph. aureus). some increase in isolations was obtained w ...	1978	101553
[epidemiological study on beta hemolytic streptococci among healthy school children in toda city, saitama (author's transl)].		1978	101618
serum protein electrophoresis in healthy subjects and patients with liver disease.		2000	101684
[hyperosmolar nonketotic diabetic coma--2 cases, with special reference to their neurologic symptoms].		2000	101695
[speech disorders and malocclusion. the effect of frequently occurring oral abnormalities on the development of speech disorders].		2000	101775
[medical education is missing its purpose and aims].		2000	101781
[practice in cooperation: german tumor centers].		2000	101785
[recent findings in dermatophytic skin diseases (author's transl)].	the most important current research centers on immunobiological questions. it is suggested that the delayed trichophyton reaction is the immune mechanism which protects patients after a primary dermatophyte infection. griseofulvin is the treatment of choice today. the questionnaire sent to all practising dermatologists in germany investigated the frequency of certain possible serious side effects. the new once daily 500 mg griseofulvin tablet will have to be in clinical use for some time yet bef ...	2000	101790
[w. ch. hecker's stand on circumcision].		2000	101809
[prostatitis inhibiting fertility. gonococci superseded by other microbes].		1978	101822
topographic localisation of insulinogenic and insulinoprival areas in the hypothalamus.	electrical stimulation of hypothalamic areas through stereotaxically implanted electrodes were carried out in conscious male rhesus monkeys. there was a significant increase in immunoreactive insulin (iri) following laterla hypothalamus (lha) stimulation. an opposite response was obtained from ventromedial hypothalamus (vmh). thus, insulinogenic and insulinoprival responses were obtained from feeding and satiety, suggesting a significant role of insulin in the regulation of food intake.	1978	102526
purification and some properties of porcine brain mitochondrial monoamine oxidase b.		1978	103556
insulin counteraction of alpha-adrenergic effects on liver glycogen metabolism.	insulin counteracted the effects of a pure alpha-adrenergic agonist, phenylephrine, on hepatocyte glycogen synthase and phosphorylase. these results argue against current concepts of insulin increasing cytoplasmic ca2+ concentration.	1978	103580