Publications

[diagnosis and course of synovial sarcoma. comparison of x-ray diagnosis and bone scintigraphy].	the unfavourable prognosis of malignant synoviomas makes it essential to arrive at an early diagnosis. the early clinical symptoms and radiological appearances may be minimal and sometimes absent. it is therefore advisable to obtain bone scintigrams with perfusion and early images as well as the radiographs. the local extent of the tumour can be evaluated by ultrasound and ct. angiography is required only if the relationship to the vessels cannot otherwise be ascertained, or if intra-arterial th ...	2010	3008260
sulfite oxidase from chicken liver. the role of imidazole and carboxyl groups for the reaction with cytochrome c.	oxidation of sulfite to sulfate by sulfite oxidase is inhibited when the enzyme is treated with reagents known to modify imidazole and carboxyl groups. modification inhibits the oxidation of sulfite by the physiological electron acceptor cytochrome c, but not by the artificial acceptor ferricyanide. this indicates interference with reaction steps that follow the oxidation of sulfite by the enzyme's molybdenum cofactor. reaction with diethylpyrocarbonate modifies ten histidines per enzyme monomer ...	1986	3019695
sulfite oxidase from chicken liver. the role of imidazole and carboxyl groups for the reaction with cytochrome c.	oxidation of sulfite to sulfate by sulfite oxidase is inhibited when the enzyme is treated with reagents known to modify imidazole and carboxyl groups. modification inhibits the oxidation of sulfite by the physiological electron acceptor cytochrome c, but not by the artificial acceptor ferricyanide. this indicates interference with reaction steps that follow the oxidation of sulfite by the enzyme's molybdenum cofactor. reaction with diethylpyrocarbonate modifies ten histidines per enzyme monomer ...	1986	3019695
alpha-adrenoceptor responsiveness in the aged rat.	the effects of ageing on vascular alpha 1- and alpha 2-adrenoceptors were examined using anaesthetised and pithed young (3-7 months) and old (21-24 months) sprague-dawley rats. in pithed animals, the pressor and cardioinhibitory effects of the alpha 2-adrenoceptor agonist xylazine were significantly reduced in old animals (8- and 6-fold shift), but the pressor effects of the alpha 1-adrenoceptor agonist amidephrine were not significantly altered by ageing. in anaesthetised rats, the pressor resp ...	1986	3019712
alpha-adrenoceptor responsiveness in the aged rat.	the effects of ageing on vascular alpha 1- and alpha 2-adrenoceptors were examined using anaesthetised and pithed young (3-7 months) and old (21-24 months) sprague-dawley rats. in pithed animals, the pressor and cardioinhibitory effects of the alpha 2-adrenoceptor agonist xylazine were significantly reduced in old animals (8- and 6-fold shift), but the pressor effects of the alpha 1-adrenoceptor agonist amidephrine were not significantly altered by ageing. in anaesthetised rats, the pressor resp ...	1986	3019712
u3 sequences from htlv-i and -ii ltrs confer px protein response to a murine leukemia virus ltr.	human t-cell leukemia virus (htlv) types i and ii are unusual among replication-competent retroviruses in that they contain a fourth gene (chi) necessary for replication. the chi gene product, p chi, transcriptionally transactivates the viral long repeat (ltr), and is thus a positive regulator. to investigate p chi transactivation, sequences from the u3 regions of the ltrs of htlv-i and -ii were inserted into the moloney murine leukemia virus (m-mulv) ltr by recombinant dna techniques. transient ...	1987	3027896
influence of dietary fiber on xylanolytic and cellulolytic bacteria of adult pigs.	xylanolytic and cellulolytic bacteria were enumerated over an 86-day period from fecal samples of 10 8-month-old gilts that were fed either a control or a 40% alfalfa meal (high-fiber) diet. fecal samples were collected from all pigs on days 0, 3, 5, 12, 25, 37, 58, and 86. overall, the numbers of xylanolytic bacteria producing greater than 5-mm-diameter zones of clearing on 0.24% xylan roll tube medium after 24 to 36 h of incubation were 1.6 x 10(8) and 4.2 x 10(8)/g (dry weight) of feces for t ...	1987	3030194
relationship of histologic grade of hepatocellular carcinoma (hcc) to tumor size, and demonstration of tumor cells of multiple different grades in single small hcc.	the histologic features of 65 surgically resected cases of hepatocellular carcinoma (hcc) were studied, and the cellular differentiation was graded from i to iv according to edmondson-steiner's classification. hcc cells of 2 or more grades were seen in 31 (47.7%) of the 65 cases. there was no significant difference in the proportion of hcc composed of tumor cells of more than one histologic grade between hccs with association with liver cirrhosis and without cirrhosis. among these 31 cases, extr ...	2011	3033422
molecular cloning of a xylanase gene from bacteroides succinogenes and its expression in escherichia coli.	a gene coding for xylanase synthesis in bacteroides succinogenes was isolated by cloning, with escherichia coli hb101 as the host. after partial digestion of b. succinogenes dna with sau3a, fragments were ligated into the bamhi site of pbr322 and transformed into e. coli hb101. of 14,000 colonies screened, 4 produced clear halos on remazol brilliant blue-xylan agar. plasmids from two stable clones recovered exhibited identical restriction enzyme patterns, with the same 9.4-kilobase-pair (kbp) in ...	1987	3034151
activity of fiber-degrading microorganisms in the pig large intestine.	the large intestine is comparable to the rumen fermentation in many aspects; however, it is understood less well. fiber in the form of cellulose and hemicellulose is one of the major substrates fermented in the large intestine. various studies suggest that the pig can utilize fiber for growth, and up to 30% of its maintenance energy may be derived from volatile fatty acids produced in the large intestine. the total number of microorganisms in the pig large intestine do not change when a high fib ...	1987	3040656
purification and properties of a 1,3-1,4-beta-d-glucanase (lichenase, 1,3-1,4-beta-d-glucan 4-glucanohydrolase, ec 3.2.1.73) from bacteroides succinogenes cloned in escherichia coli.	a 1,3-1,4-beta-d-glucanase (lichenase, 1,3-1,4-beta-d-glucan 4-glucanohydrolase, ec 3.2.1.73) from bacteroides succinogenes cloned in escherichia coli was purified 600-fold by chromatography on q-sepharose and hydroxyapatite. the cloned enzyme hydrolysed lichenin and oat beta-d-glucan but not starch, cm(carboxymethyl)-cellulose, cm-pachyman, laminarin or xylan. the enzyme had a broad ph optimum with maximum activity at approx. ph 6.0 and a temperature optimum of 50 degrees c. the ph of elution f ...	1988	3063255
localization of the kras2 oncogene in the domestic rabbit (oryctolagus cuniculus).	the kras2 gene was localized in the rabbit by chromosomal in situ hybridization, using a 3h-labeled human cdna probe. there were 201 silver grains on 144 metaphase spreads; 12.9% of the grains resided on chromosome 16, and 54% of these grains were located close to the centromere at 16p11----q11. statistical analysis indicated that labeling at this region represents a significant deviation from a random distribution and thus provided evidence for the assignment of kras2 to 16p11----q11. in additi ...	1988	3073912
estradiol-binding proteins from mycelial and yeast-form cultures of paracoccidioides brasiliensis.	paracoccidioides brasiliensis, the etiologic agent of paracoccidioidomycosis, causes disease much more frequently in men than it does in women, suggesting that the hormonal milieu of the host might influence p. brasiliensis pathogenicity. we recently demonstrated that cytosol from yeast cultures of p. brasiliensis contains a high-affinity, low-capacity, tritiated 17 beta-estradiol [( 3h]estradiol)-binding protein. estradiol and, to a lesser degree, diethylstilbestrol (des), inhibited the transfo ...	1986	3079729
the ability of single sex infections of schistosoma japonicum to induce resistance to reinfection in mice.	in four experiments, mice harbouring an average 50, 76 or over 200 schistosoma japonicum female worms were not resistant when challenged six to eight weeks after infection. the female worms from these single sex infections were stunted and immature (average length 4.6 mm) and induced no overt pathology in the host. male worm burdens of 60, 135 or 140 also induced little or no resistance to challenge in the host. the males from these single sex infections were fully grown for their age (average l ...	1986	3091678
[occupational health program for the workers of health centers].		2011	3105075
fermentation of xylans by butyrivibrio fibrisolvens and other ruminal bacteria.	the ability of butyrivibrio fibrisolvens and other ruminal bacteria (6 species, 18 strains) to ferment a crude xylan from wheat straw or to ferment xylans from larchwood or oat spelts was studied. liquid cultures were monitored for carbohydrate utilization, cell growth (protein), and fermentation acid production. b. fibrisolvens 49, h17c, actf2, and d1 grew almost as well on one or more of the xylans as they did on cellobiose-maltose. b. fibrisolvens 12, r28, a38, x10c34, ard22a, and x6c61 exhib ...	1987	3124741
pepsinogen secretion from perifused frog peptic glands: rapid transients detected with a modified pepsin assay.	in order to define the early transient responses of peptic cells to stimulation, we have modified the acidified hemoglobin substrate digestion method for pepsin to provide a very sensitive, linear (10-250 ng/ml), reproducible, inexpensive (less than 3 cents/sample) and simple semi-automated assay. using a specially designed perifusion chamber, this method was used to accurately measure secretion at 1 min intervals from approximately 3 mg of isolated peptic glands from the esophageal peptic organ ...	2011	3126374
[chronic ventilation in the netherlands].		2011	3126405
drop of the weak stuff.		2011	3139240
gene-specific differences in the aflatoxin b1 adduction of chicken erythrocyte chromatin.	mature and immature chicken erythrocyte nuclei were treated with activated aflatoxin b1 (2,3-dichloroaflatoxin b1), producing covalently bound dna adducts. this reaction produces alkali-labile sites in the dna which can be identified by using a variation of the maxam-gilbert sequencing procedure. we determined the aflatoxin b1 accessibility of defined regions of the erythroid genome by using different specific probes and monitoring the disappearance of similar-sized fragments generated by restri ...	1988	3142684
cloning and expression of a bacteroides succinogenes mixed-linkage beta-glucanase (1,3-1,4-beta-d-glucan 4-glucanohydrolase) gene in escherichia coli.	a pseudorandom genomic library of bacteroides succinogenes dna, cloned into puc8 in escherichia coli, was screened for beta-glucanase activity on 0.1% lichenan plates. six high-activity clones, containing identical 5.2-kilobase inserts of b. succinogenes dna, were obtained. the clones exhibited activity solely on beta-glucan substrates containing beta-(1----3)(1----4) linkages, thus manifesting a specific fibrolytic enzyme previously unrecognized in b. succinogenes. a subclone (pji10) of the ori ...	1988	3145707
effect of phenolic monomers on the growth and beta-glucosidase activity of bacteroides ruminicola and on the carboxymethylcellulase, beta-glucosidase, and xylanase activities of bacteroides succinogenes.	trans-p-coumaric acid inhibited the growth of bacteroides ruminicola on both cellobiose and glucose, while trans-ferulic acid and vanillin retarded growth. the phenolic monomers varied in their potential to inhibit the bacteroides succinogenes beta-glucosidase, carboxymethylcellulase, and xylanase, with p-coumaric acid being the most inhibitory. the b. ruminicola beta-glucosidase was inhibited less than 10% by all three compounds.	1988	3146948
plasma nitroglycerin levels, blood pressure and apical heart rate variations to site of application of nitroglycerin ointment.	the purpose of this study was to observe changes in plasma nitroglycerin levels, systolic and diastolic blood pressure, and apical heart rate after the administration of nitroglycerin ointment to selected sites. the sample consisted of 15 subjects with a diagnosis of coronary artery disease. the four application sites used were the fifth intercostal space of the left anterior chest, medial aspect of the left upper arm, medial aspect of the left thigh, and medial aspect of the left lower leg. the ...	2011	3147433
non-immune igg f(ab')2 binding to group c and g streptococci is mediated by structures on gamma chains.	the present investigation was designed to determine whether the heavy or the light immunoglobulin chain is involved in the non-immune binding of igg f(ab')2 fragments to specific surface receptors on human group c and g streptococci. purified human polyclonal igg was mildly reduced with dithiothreitol and alkylated with iodoacetamide. light (l) and heavy (h) chains were separated. intact igg and purified l and h chains of polyclonal immunoglobulin g were tested in an inhibition assay for non-imm ...	1985	3156400
glomerular electron-dense deposits in childhood iga nephropathy.	an electron-microscopic study of the glomeruli was made on 154 children with iga nephropathy and no evidence of systemic disease, in whom immunofluorescence microscopy had shown diffuse mesangial deposition of iga. mesangial deposits were observed in all but eight children. subepithelial deposits were observed in 40 children and were almost always accompanied by both mesangial and subendothelial deposits. subepithelial deposits were significantly associated with more severe clinical presentation ...	2011	3158115
adenocarcinoma metastatic to the mandibular condyle.	two cases of metastatic lesions presenting in the mandibular condyle as temporo-mandibular joint pain dysfunction syndrome are presented with a discussion on the mechanisms of tumour metastases to bone.	2011	3165389
graded requirement for the zygotic terminal gene, tailless, in the brain and tail region of the drosophila embryo.	we have used hypomorphic and null tailless (tll) alleles to carry out a detailed analysis of the effects of the lack of tll gene activity on anterior and posterior regions of the embryo. the arrangement of tll alleles into a continuous series clarifies the relationship between the anterior and posterior functions of the tll gene and indicates that there is a graded sensitivity of anterior and posterior structures to a decrease in tll gene activity. with the deletion of both anterior and posterio ...	2011	3168787
establishment of bacteroides succinogenes and measurement of the main digestive parameters in the rumen of gnotoxenic lambs.	we attempted to determine the degree of diversification of the microflora that allow the establishment of bacteroides succinogenes s85 in the rumen of gnotoxenic lambs. four lambs (group i) received an inoculum orally, composed of 182 noncellulolytic bacterial strains (inoculum 1) previously isolated from the rumen of conventional young lambs. two lambs (group ii) were inoculated with 32 strains (inoculum 2) selected among the 182 strains of inoculum 1. two lambs (group iii) received an inoculum ...	1988	3208206
effects of plasma ochratoxin a and luminal ph on the jejunal absorption of ochratoxin a in rats.	the effects of iv injection of ochratoxin a (oa) on its absorption from the jejunum in rats were studied in vivo to demonstrate the jejunal absorption of oa in relation to the oa level in blood plasma. in addition the effects of the ph of the medium on oa uptake by the everted jejunum of the rat were studied in vitro to assess the contribution made by transfer of the non-ionized form of oa to the jejunal absorption of the toxin. the in vivo study showed that oa was absorbed from the jejunum even ...	1988	3209137
detection of cellulose-binding proteins in electrophoresis gels by filter paper affinity blotting.	proteins separated in electrophoresis gels were tested for the ability to bind cellulose by a simple blotting procedure. proteins were blotted onto whatman no. 1 filter paper by diffusion or by electrophoretic transfer and detected by coomassie blue staining. certain proteins released into culture supernatant by bacteroides succinogenes nr9 (atcc 43854) adhered strongly to cellulose, but were not found to have carboxymethylcellulose activity. boiling of samples prior to electrophoresis eliminate ...	1988	3218733
[varices caused by ostial insufficiency of the internal saphenous vein].		2011	3222322
[the use of flavor profile analysis for optimization of gustatory characteristics in formulated foods].		2012	3270400
an outbreak of cutaneous leishmaniasis.		2011	3271361
intracellular processing of measles virus fusion protein.	intracellular processing of measles virus fusion (f) protein was studied by radiolabeling and immunoprecipitation with a monoclonal antibody against f protein. the cleavage of f protein into f1 and f2 subunits was complete after 5 hours of chase during which the growth of oligosaccharide chains on the f2 domain of f protein continued. the addition of terminal sialic acid conferred a strong negative charge on the f2 subunit. f protein expressed on the cell surface was removed by a fungal semi-alk ...	1988	3277595
effects of alkaline hydrogen peroxide treatment on in vitro degradation of cellulosic substrates by mixed ruminal microorganisms and bacteroides succinogenes s85.	the effects of sodium hydroxide (naoh) and alkaline hydrogen peroxide (ahp) treatments on wheat straw (ws) and various cellulosic substrates were determined by measuring susceptibility to degradation by mixed ruminal organisms or bacteroides succinogenes s85. in vitro incubations were used to measure differences in fermentation resulting from each successive step in the ahp treatment process. in vitro incubations through 48 or 108 h were conducted to measure these differences. the ahp treatment ...	1988	3291761
hemorrhagic shock induces bacterial translocation from the gut.	sepsis and multiple organ failure are common after hemorrhagic shock. the goal of the current experiments was to determine whether hemorrhagic shock would promote the translocation of bacteria from the gut to visceral organs. twenty-four hours after being subjected to sham shock, or 30, 60, or 90 minutes of shock (30 mm hg), rats were sacrificed and their organs quantitatively cultured for translocating bacteria. there was a direct relationship between the duration of hemorrhagic shock and the 2 ...	1988	3294427
the microcirculatory society eugene m. landis award lecture. capillaries and cowboys.		2012	3302620
[subcutaneous rupture of tendons and muscles of the extremities].	under study there were 278 patients with 285 subcutaneous ruptures of tendons and muscles of the upper and lower extremities. the tendon of the long head of the humeral biceps muscle and achilles tendon are most liable to subcutaneous ruptures (123 patients--43.2% and 97 patients--34% respectively). pathohistological examinations have shown that subcutaneous ruptures of tendons and muscles usually take place against the background of dystrophic alterations reducing their mechanical strength. the ...	2012	3303625
corneal transplantation using 4-week banked donor material. long-term results.	thirty-six corneal transplantations employing banked donor material maintained during prolonged storage (mean: 29.5 days) in organ culture at 31 degrees c were followed for 5 years. the overall graft survival was 80% , and graft failures were almost exclusively found in a pre-operatively defined risk group where the survival rate was 49.6% compared with 95.5% in the non-risk group. five years after transplantation the mean central thickness of surviving grafts was 0.52 mm and the mean endothelia ...	2012	3303817
the human met oncogene is a member of the tyrosine kinase family.	prolonged exposure of a nontumorigenic human osteogenic sarcoma cell line (hos) with the direct acting carcinogen n-methyl-n'-nitro-n-nitrosoguanidine (mnng) gave rise to morphologically transformed cells which were tumorigenic in nude mice and termed mnng-hos. we have shown that dna from mnng-hos cells will transform nih/3t3 cells and have isolated greater than 35 kb of human dna containing an oncogene, termed met. the activated met oncogene expresses a novel 5.0 kb rna transcript which is a hy ...	1986	3332011
[nosocomial infections of the urinary tract in urology patients].	researches effected in different nations have revealed that 5-12% of all hospitalized patients was affected with a nosocomial infection and that almost 1/3 of these were urinary tract infections. the hospitalized urological patients have a considerable proneness to contract a nosocomial urinary tract infection, because they are subjected to transurethral or suprapubic bladder catheterisms, to transurethral surgery and to the endoscopies, that are promoting maneuvers the urinary tract infections. ...	1988	3340313
chromosome analysis of human oocytes and embryos: does delayed fertilization increase chromosome imbalance?	thirty per cent of a sample of 120 unfertilized human oocytes carried chromosome abnormalities highly correlated with maternal age (38% in patients greater than 35, as compared with 24% in younger patients). fertilized eggs, when observed 17 h after insemination, showed in 1.6% a single pronucleus suggesting parthenogenetic activation. in 92% of the cases two pronuclei were observed and the rate of chromosome anomalies depended on the morphological aspect of the embryos. triploidy was also encou ...	1988	3350934
storage of human platelet concentrates in an artificial medium without dextrose.	it was shown previously that human blood platelets stored in an artificial medium (pcd) for up to 5 days remain functional in vitro and have normal survival and recovery in vivo. this report demonstrates that the medium can be simplified further by the removal of dextrose, leaving for study a medium consisting simply of balanced salts and citrate anticoagulant (pc). some dextrose, 3.2 mm, was present in the fresh pc platelet concentrates due to plasma carryover in the production of platelet conc ...	1988	3368933
spinal projections of renal afferent nerves in the rat.	this study was designed to describe renal afferent information with respect to its intraspinal projections, convergence with cutaneous inputs, ascending projections, and modulation by descending fiber tracts. extracellular recordings were made from neurons in the spinal gray while electrically stimulating the renal nerves in chloralose-anesthetized, artificially ventilated rats. almost all neurons (n = 119) were spontaneously active. some responses consisted of high-frequency bursts while others ...	1988	3370480
sunburn in children in the west of scotland.	leaving babies and young children out in the sun during periods of unexpected exceptionally fine weather resulted in 142 children being treated for sunburn in the royal hospital for sick children in glasgow over a 6-year period. care-givers should be warned of the potential hazards of overexposure to sunshine.	2012	3370521
reversal of pulmonary hypoxic vasoconstriction with pentoxifylline and aminophylline in isolated lungs.	pentoxifylline (pent) is a xanthine known to improve erythrocyte deformability and thought to have little effect on smooth muscle tone. in this study i examined the direct effects of pent on the pulmonary vasculature of isolated lungs and compared them with the effects of aminophylline. the object was to study whether pent can reverse the hypoxic pressor response (hpr) by its hemorheological property. changes in pulmonary arterial pressure (pa) of isolated lungs (pigs and rats) perfused at const ...	1988	3370545
isolation and characterization of endoglucanases 1 and 2 from bacteroides succinogenes s85.	two endoglucanases designated eg1 and eg2 were purified by column chromatography from the nonsedimentable extracellular culture fluid of bacteroides succinogenes s85. they accounted for approximately 32 and 11%, respectively, of the total endoglucanase present in the nonsedimentable fraction. the most active enzyme (eg1) had a molecular weight of 65,000, pi of 4.8, and temperature and ph optima of 39 degrees c and 6.4, respectively. the km for carboxymethyl cellulose was 3.6 mg/ml, and the vmax ...	1988	3384798
purification and characterization of a chloride-stimulated cellobiosidase from bacteroides succinogenes s85.	a cellobiosidase with unique characteristics from the extracellular culture fluid of the anaerobic gram-negative cellulolytic rumen bacterium bacteroides succinogenes grown on microcrystalline cellulose (avicel) in a continuous culture system was purified to homogeneity by column chromatography. the enzyme was a glycoprotein with a molecular weight of approximately 75,000 and an isoelectric point of 6.7. when assayed at 39 degrees c and ph 6.5, the activity of the enzyme with p-nitrophenyl-beta- ...	1988	3384799
use of phylogenetically based hybridization probes for studies of ruminal microbial ecology.	to address the long-standing need for more precise descriptions of natural microbial ecosystems, 16s rrnas were used to track certain species and phylogenetically coherent groups of microorganisms in their natural setting without culturing. species- and group-specific 16s rrna-targeted oligonucleotide hybridization probes were developed to enumerate various strains of bacteroides succinogenes and lachnospira multiparus-like organisms in the bovine rumen before, during, and after perturbation of ...	1988	3389805
satellite cells in the regenerated and regrafted skeletal muscles of rats.	soleus (sol) muscles were grafted into extensor digitorum longus (edl) muscle beds (edl-first-graft). sixty days later, some mature edl-first-grafts were regrafted into their own beds (edl-second-grafts). fully regenerated muscle fibers and satellite cells were observed in both types of mature grafts. the ratios of satellite cell nuclei per total nuclei (myonuclei and satellite cell nuclei) were 4.81 +/- 0.47% for edl-2nd graft, 4.26 +/- 0.51% for edl-1st-graft, 4.30 +/- 0.33% for control sol, a ...	1988	3396655
the effect of tissue culture agar on chromosome breakage, sister-chromatid exchanges and clonogenicity in human cells.	to investigate the cytogenetic effects of electromagnetic fields, a system containing an agar gel was developed to support the growth of various human cell types (peripheral lymphocytes, lymphoblasts, and fibroblasts). when compared to alioquots of identical cells, grown in plastic culture vessels, statistically significant increases in the frequencies of chromosome breakage, sister-chromatid exchange and decreased cloning efficiency were observed in those cells cultured in the agar. these resul ...	1988	3398870
cancer, stress and personality: a correlational investigation of life-events, repression-sensitization and locus of control.	this study investigated the hypothesis that stress-inducing life experiences and the personality factors of external locus of control and tendency to repress emotion are relevant in the aetiology of cancer. fifty cancer patients scored higher than 50 matched controls on a life-events scale (especially negative events), but were found to be lower on repression of emotion. there was no difference between groups on locus of control.	2012	3401426
synthesis and analgesic effect of n-substituted 5-arylidene-6-methyl-3-(4h)-pyridazinones.		2012	3416373
cemented total hip arthroplasty with contemporary techniques. a five-year minimum follow-up study.	a retrospective clinical and roentgenographic review was performed on 251 consecutive cemented total hip arthroplasties (tha) performed from 1978 to 1980 that had been followed a minimum of five years (range, five to seven years). all arthroplasties involved the use of a harris design ii femoral stem, an intramedullary plug, a cement gun, and pulsatile lavage of both the acetabulum and the femoral canal. at the final follow-up examination, 98% of the patients had excellent results. the average h ...	2012	3416521
effects of potassium ion concentrations on the antimicrobial activities of ionophores against ruminal anaerobes.	the antimicrobial activities of monensin and lasalocid against representative strains of ruminal bacteria were evaluated in medium containing three different concentrations of potassium (1.3, 7.9, or 23.3 mm). the growth of eubacterium ruminantium was inhibited by low concentrations of ionophores (less than or equal to 0.16 mg/liter), while the strain of streptococcus bovis tested was resistant to high concentrations of ionophores (40 mg/liter) at all potassium concentrations tested. the mics of ...	1987	3426214
amino acid analysis: a fall-off in performance.		2012	3429525
[complicated dislocation of the 3d lumbar vertebra].		2012	3438074
[a case from practice (100). patient: mr. a.d., born 4-1-1961, construction worker].		2012	3441718
[fixation in surgical orthodontics].		2012	3463488
molecular mimicry in reiter's syndrome: cytotoxicity and elisa studies of hla-microbial relationships.	the pathogenic links between hla antigens, certain bacterial infections and arthritis have not yet been characterized. the hypothesis of cross-reactivity between hla b27, the marker of disease susceptibility for these disorders, and the provocative microorganism has been suggested by studies of klebsiella and ankylosing spondylitis. the present study examines the possibility of molecular mimicry between hla b27 and two organisms implicated more directly in reactive arthritis, yersinia enterocoli ...	1986	3488263
transcatheter intracavitary fibrinolysis of infected extravascular hematomas.		2012	3492117
[rapid decisions in the situation of dichotic choice: an integrated approach which takes into account onset snd execution of the response].		2012	3502909
primary sex determination in the nematode c. elegans.	most nematodes have xo male/xx female sex determination. c. elegans is anomalous, having xx hermaphrodites rather than females. the hermaphrodite condition appears to result from the modification of a basic male/female sex-determination system, which permits both spermatogenesis and oogenesis to occur within a female soma. this modification is achieved by a germ-line-specific control acting at one step in a cascade of autosomal regulatory genes, which respond to x-chromosome dosage and direct ma ...	2012	3503722
in vitro reversal of cardiac deterioration in septic shock with tetraethylammonium chloride.	overwhelming sepsis associated with cardiac failure continues to be a major clinical problem. this is commonly associated with a failure to respond to conventional pharmacologic therapy. this study was undertaken to see if manipulations of the electrophysiologic defects previously described by treatment with tetraethylammonium chloride (tea) would be advantageous. septic shock was induced in rabbits by a lethal dose of escherichia coli. peak tension and velocities of contraction and relaxation w ...	1986	3510606
fodrin is part of a filamentous cortical sheath of the detergent resistant cytoskeleton of cultured cells before and after cytochalasin treatment.	cytoskeletons of cultured cells prepared under mild conditions in the presence of "stabilization' buffer contain most of the fodrin present in the cells. the fodrin in these cytoskeletons was localized by immunofluorescence microscopy and found to be present in a cortical sheath of fine filaments. in general, the filamentous distribution showed no correspondence with actin bundles as revealed by double-label fluorescence microscopy. however, in cells with large and abundant stress fibers, some c ...	1986	3514218
secretory protein translocation in a yeast cell-free system can occur posttranslationally and requires atp hydrolysis.	we describe an in vitro system with all components derived from the yeast saccharomyces cerevisiae that can translocate a yeast secretory protein across microsomal membranes. in vitro transcribed prepro-alpha-factor mrna served to program a membrane-depleted yeast translation system. translocation and core glycosylation of prepro-alpha-factor were observed when yeast microsomal membranes were added during or after translation. a membrane potential is not required for translocation. however, atp ...	1986	3517001
secretory protein translocation in a yeast cell-free system can occur posttranslationally and requires atp hydrolysis.	we describe an in vitro system with all components derived from the yeast saccharomyces cerevisiae that can translocate a yeast secretory protein across microsomal membranes. in vitro transcribed prepro-alpha-factor mrna served to program a membrane-depleted yeast translation system. translocation and core glycosylation of prepro-alpha-factor were observed when yeast microsomal membranes were added during or after translation. a membrane potential is not required for translocation. however, atp ...	1986	3517001
typical and atypical resection techniques of hepatic metastases.		2012	3526467
multiple dose insulin regimen using the novopen.		2013	3534657
microinjection of the ras oncogene protein into nonestablished rat embryo fibroblasts.	early (twice) and late (eighth) passage nonestablished rat embryo fibroblasts exhibit dramatically different responses to microinjection of the oncogenic form (t24) of the ras protein. late passage cells respond like established cultures in that they both synthesize dna and divide in response to the oncogenic protein. however, early passage cells are shown to be much less responsive to the introduction of this protein in terms of the threshold concentration required to elicit a mitogenic respons ...	1986	3536079
high-density lipoprotein turnover.	high-density lipoprotein (hdl) metabolism has been reviewed from information derived from turnover studies in humans. the two major hdl apoproteins ai and aii have different removal rates, reflecting the faster catabolism of hdl2 than of hdl3. this is caused by the continual cycle of formation of hdl2 from hdl3 and its reversion to hdl3, in response to the need to transport cholesterol and other lipids from extrahepatic cells and catabolized triglyceride-rich lipoproteins. the conversion of hdl2 ...	2013	3544764
a pathology textbook of 1838: g. freckleton, outlines of general pathology.		2012	3545987
characteristics of the endoglucanase encoded by a cel gene from bacteroides succinogenes expressed in escherichia coli.	a cel gene from bacteroides succinogenes inserted into the vector puc8 coded for an enzyme which exhibited high hydrolytic activity on carboxymethylcellulose, p-nitrophenylcellobioside, and lichenan and low activity on laminarin and xylan. the enzyme was not synthesized by the escherichia coli host when cells were cultured in complex medium containing added glucose. in the absence of added glucose, the endoglucanase and cellobiosidase activities synthesized were partitioned into the periplasmic ...	1987	3548592
ambulatory pediatric association. program and abstracts, twenty-seventh annual meeting. april 27-may 1, 1987, anaheim, ca.		2013	3565319
interactions between treponema bryantii and cellulolytic bacteria in the in vitro degradation of straw cellulose.	to assess the contribution of individual bacterial species to the overall process of cellulose digestion in the rumen, cellulolytic bacteria (bacteroides succinogenes and ruminococcus albus) were tested as pure cultures and as cocultures with noncellulolytic treponema bryantii. in studies of in vitro barley straw digestion, treponema cocultures surpassed pure cultures of the cellulolytic organisms in dry matter disappearance, volatile fatty acid generation, and in the production of succinic acid ...	1987	3567744
electron microscopic study of the methylcellulose-mediated detachment of cellulolytic rumen bacteria from cellulose fibers.	the presence of methylcellulose prevents the attachment of cellulolytic rumen bacteria to cellulose fibers. the addition of methylcellulose to pure cultures of these organisms in which the cells are already adherent to cellulose causes their detachment from this insoluble substrate and the inhibition of their growth. methylcellulose is not used as a carbon source by these organisms and has no effect on their growth when glucose and cellobiose are the carbon sources. attached cells of bacteroides ...	1987	3567745
approach to hypoglycemia in adults.		2013	3568598
[iga nephropathy].		2013	3581142
a novel technique for measuring hypothalamic and pituitary hormone secretion rates from collection of pituitary venous effluent in the normal horse.	we have described a novel technique for collecting pituitary venous effluent in the horse by placing a cannula in the intercavernous sinus close to the outlet of the pituitary veins using a venous pathway unique to equids. cannula placement and blood collection are carried out painlessly in fully conscious, ambulatory, unstressed animals. there is no interference to hypothalamic, pituitary or target organ function. the blood collected contains readily measurable concentrations of gonadotrophin-r ...	1987	3585231
sacrococcygeal teratoma masquerading as fistula-in-ano.		2013	3585893
sudden deafness in a patient with temporal arteritis.	a patient with anemia and elevated erythrocyte sedimentation rate presented with sudden hearing loss. the diagnosis of temporal arteritis was verified by temporal biopsy. initiation of corticosteroid therapy reversed the disease manifestations and within a short period improved the patient's hearing.	2013	3599012
depression in spontaneous cell-mediated cytotoxicity occurs during hemodialysis.	nk activity against k 562 target cells and the percentage of hnk-1+ lymphocytes in peripheral blood were evaluated in 24 patients on maintenance hemodialysis prior to and during post hemodialysis session. no difference was found in the nk activity of these patients before hemodialysis and normal subjects. on the other hand patients had a decreased number of hnk-1+ cells. during hemodialysis, the nk activity as well as the hnk-1+ cell count decreased. no correlation was found between these parame ...	2012	3608252
enprofylline pharmacokinetics in children with asthma.	the pharmacokinetics of intravenous enprofylline has been studied in 8 children with asthma. the mean plasma half-life of enprofylline (1.0 h) was considerably shorter than that previously reported in adults. the half-life determined from log urine excretion rate data was identical to the plasma half-life, so urine excretion could be used as a non-invasive method to study the elimination rate. as in adults, urinary recovery of unchanged drug averaged 89%, and the volume of distribution, vz, aver ...	2013	3622600
selective memory impairment by phencyclidine in rats.	phencyclidine (pcp) users sometimes report lack of recall of events occurring while they are under the influence of the drug. the present experiment was designed to test whether rats remember information learned after pcp administration. rats were trained to choose one arm of a t-maze to obtain a food reward. the following day they were injected with either pcp (1 mg/kg) or vehicle and trained to choose the opposite arm for a reward (reversal learning). a third group of rats received neither inj ...	1987	3622624
evaluating a geriatrics program in an acute-care hospital.		2013	3623140
[formaldehyde allergies].		2013	3645758
[reconstructive plastic surgery of the humeral condyles following removal of endoprostheses of the elbow versus arthrodesis].	the condyles of the elbow are of utmost importance for the stability of this joint. this is particularly evident in cases where elbow prostheses had to be removed because of loosening or infection and where the condyles had been deliberately resected at the primary operation. in order to obtain a functional elbow with sufficient stability and mobility after removal of the prostheses, we can reconstruct the condyles by means of a large autologous bone graft, which we take from the midpart of the ...	2013	3658417
[spontaneous occlusion of intracerebral vascular malformations].		2013	3659327
[cardiac autonomic neuropathy in type i diabetics].		2013	3660679
[realities in the diagnosis of bronchial carcinoma in clinical and general practice].	in 100 patients with lung cancer the diagnostic procedure, results of clinical staging and therapeutic sequelae were analysed retrospectively and compared to a similar group of patients 10 years previously. during the 10 years' interval there was a remarkable shortening of the time between the onset of symptoms and the diagnosis, from 20 weeks to the present 10 weeks. despite this acceleration the number of patients undergoing curative surgical resection increased only from 15 to 17%. inoperabil ...	2013	3672088
serum tryptophan and cataract.	total serum tryptophan concentrations were measured in 74 cataractous patients and 124 controls. no significant differences were observed in the mean values for the cataractous and normal subjects, 11.4 +/- 2.6 and 11.3 +/- 2.2 micrograms/ml respectively, or in the range of values, 7.4-17.1 and 7.3-17.4 micrograms/ml respectively. these results do not support previous reports that serum tryptophan is elevated in cataractous subjects.	2013	3675914
registry and tabulations of orthotopic total artificial hearts in humans.		2013	3675942
clinical phase ii trial of recombinant dna interferon (interferon alpha 2b) in patients with metastatic malignant melanoma.	twenty-four patients with histologically proven metastatic malignant melanoma were included in a phase ii trial of human dna recombinant interferon (rdna ifn alpha 2). they were given 10 x 10(6) iu of ifn alpha 2 subcutaneously three times a week until progression of disease or major intolerance developed. twenty-two patients were evaluable for toxicity and response. general manifestations of intolerance were seen in all the patients. hematologic toxicity was seen in six patients and therapy had ...	1986	3719515
18q+, the progeny of a balanced translocation t(1;18)mat: case report with necropsy findings.	a female infant with additional genetic material on the long arm of chromosome 18 is described. cytogenetic studies of the infant and her mother showed that the altered region resulted from an unbalanced translocation of part of the long arm of chromosome 1. this chromosomal abnormality has not been reported previously, according to a recent registry of abnormal chromosome patterns. the patient had hydrops fetalis and multiple congenital abnormalities, involving the cardiovascular, respiratory, ...	1986	3723558
evaluation of predictive formulae for determining metabolic rate during cold water immersion.	five models predicting shivering thermogenesis on the basis of steady state skin and core temperature were evaluated: hayward et al., stolwijk and hardy,; nadel et al.,; timbal et al., and brown and brengelmann, using the empirical data derived from a cold water immersion study by morrison et al. a residual analysis indicated that all models generated substantial errors of prediction. the best overall predictors were expressions suggested by hayward et al., while the predictive equation of nadel ...	2013	3741291
movement of retinal terminals in goldfish optic tectum predicted by analysis of neuronal proliferation.	quantitative, computer-assisted autoradiography was used to assess the relative rate and pattern of growth of retina and tectum in larval and early juvenile goldfish. 3h-thymidine was used to mark the boundary of retina and tectum, and the location of this boundary was charted as the eye and brain grew and added more cells. the pattern of growth is at all times discordant. the original (larval) retina becomes surrounded by annuli of new tissue, whereas the larval tectum remains adjacent to the r ...	2013	3746418
alignment of cilia in immotile-cilia syndrome.	alignment of cilia in nasal epithelial cells from eight human subjects suffering from immotile-cilia syndrome was compared with that of cells from five control subjects. individual cilia were assessed according to the orientation of their basal feet. the range of orientation of basal feet on a single cell varied from 26 degrees to 261 degrees and 54 degrees to 275 degrees in controls and patients respectively. less than 10% of the cells from each group supported cilia that were aligned randomly. ...	1986	3750315
somatic dysfunction, osteopathic manipulative treatment, and the nervous system: a few facts, some theories, many questions.		2013	3753964
toxic shock syndrome associated with tsst-1 producing coagulase-negative staphylococci.	coagulase-positive staphylococci have been isolated from more than 95% of cases of toxic shock syndrome (tss). toxic shock syndrome toxin-1 (tsst-1) is produced in more than 90% of cases. a case is described of recurrent tss in which a coagulase-negative staphylococcus was isolated from the vagina and produced tsst-1. no coagulase-positive staphylococci were isolated. coagulase-negative staphylococci should be considered as causative agents in cases of tss. assay for tsst-1 should be performed o ...	1986	3777014
phosphoenolpyruvate-dependent phosphorylation of hexoses by ruminal bacteria: evidence for the phosphotransferase transport system.	six species of ruminal bacteria were surveyed for the phosphoenolpyruvate (pep)-dependent phosphorylation of glucose. selenomonas ruminantium hd4, streptococcus bovis jb1, and megasphaera elsdenii b159 all showed significant activity, but butyrivibrio fibrisolvens 49, bacteroides succinogenes s85, and bacteroides ruminicola b1(4) showed low rates of pep-dependent phosphorylation and much higher rates in the presence of atp. s. ruminantium hd4, s. bovis jb1, and m. elsdenii b159 also used pep to ...	1986	3789722