Publications

an outbreak of nosocomial proteus rettgeri urinary tract infection.	between december 1, 1971, and november 30, 1972, 11 patients on a single physical rehabilitation ward in a large st. louis, missouri, community hospital developed proteus rettgeri urinary tract infections; p. rettgeri isolates from each patient were indole-negative and resistant in vitro to all antibiotics tested. infected patients were more likely to have indwelling urinary tract catheters than were matched control patients, and all had previously received systemic antibiotic therapy. retrospec ...	1976	1258855
antimicrobial resistance of 100 serial gram-negative isolates in two intensive care units.	to determine antimicrobial resistance pattern among gram-negative bacteria isolated from suspected sources of infections in patients hospitalized in two intensive care units (icus) at siriraj hospital from september 1991 to december 1991, minimal inhibitory concentrations of one-hundred consecutive gram-negative isolates for various antimicrobials were performed using the microbroth dilution method. of all gram-negative bacterial isolates, 25 per cent were pseudomonas aeruginosa, 22 per cent aci ...	1992	1308536
in vivo administration of recombinant growth hormone or gamma interferon activities macrophages: enhanced resistance to experimental salmonella typhimurium infection is correlated with generation of reactive oxygen intermediates.	purified and recombinant forms of growth hormone (gh) as well as of recombinant rat gamma interferon (ifn-gamma) enhance the survival of rats deprived of endogenous pituitary gh secretion by hypophysectomy (hx rats) and infected with virulent salmonella typhimurium. macrophages obtained from rats with intact pituitaries (pituitary-intact rats) or hx rats that were treated in vivo with either gh or the closely related hormone prolactin released elevated (p less than 0.05) levels of superoxide ani ...	1992	1316877
effects of professional and media warnings about the association between aspirin use in children and reye's syndrome.	the media played a central role in changing the use of aspirin among children with viral illness following reports of its association with a rare but deadly disease, reye's syndrome (rs). it did so by alerting health professionals and parents about ways to prevent rs in children. indeed, by the time aspirin product labeling was required by the fda in 1986, most of the decline in rs incidence had already occurred. in the past, media-only health education campaigns have been relatively unsuccessfu ...	2005	1316991
in vitro activity of opc-17116 compared to other broad-spectrum fluoroquinolones.	the in vitro activity of opc-17116 was compared to that of five similar fluoroquinolones (ciprofloxacin, enoxacin, norfloxacin, ofloxacin and temafloxacin). a total of 700 isolates from recent cases of clinical bacteremia were tested. fifty additional stock strains with well-characterized resistance mechanisms were also processed. the minimal concentrations inhibiting 90% of strains (mic90) of enterobacteriaceae species were for opc-17116 0.015-0.5 micrograms/ml and for ciprofloxacin 0.015-0.25 ...	1992	1327789
optimal feed temperature for an immobilized enzyme packed-bed reactor.	optimal feed temperature was determined for a nonisothermal immobilized enzymatic reaction with enzyme deactivation in a packed-bed reactor. the optimal feed temperature was obtained by maximizing the average substrate conversion over a given reaction period. simulation showed the optimal feed temperature to be strongly dependent on the flow dispersion, the reaction activation energy, the corresponding enzyme inactivation energy and the heat of reaction. it was also observed that in a plug flow ...	2006	1366867
health checks on patients 75 years and over in nottinghamshire after the new gp contract.	to investigate annual health checks for patients of 75 years and over required by the 1990 contract for general practitioners.	2006	1393076
[antibacterial activities of sisomicin against fresh clinical isolates].	to investigate antibacterial activities of sisomicin (siso), mics of siso as well as other aminoglycosides (ags) were determined against many clinical isolates which were obtained in 1991. results are summarized below: 1. no siso-resistant strains were observed among isolates of escherichia coli, citrobacter diversus, klebsiella pneumoniae, klebsiella oxytoca, enterobacter aerogenes, proteus mirabilis and morganella morganii. 2. in comparison with the results of our previous study against isolat ...	1992	1433905
[ultrasound morphology of gallstones].	using a subtile examination technique genuine information can be obtained from the interior of a gallstone--at least to a depth of 15 mm. this information should provide an indication of the homogeneous (crystalline) or inhomogeneous (non-cholesterol) structure of the stone. further systematic use of differentiating gallstone ultrasonography could become a useful additional decision making criterion for selection of gallstones suitable for conservative treatment.	2006	1449008
augmentative communication coursework needed.		2006	1456971
short frenulums.		2006	1472216
the primary structure of providencia rettgeri penicillin g amidase gene and its relationship to other gram negative amidases.	the nucleotide sequence of penicillin g amidase (pa,e.c.3.5.1.11) of providencia rettgeri was determined. we aligned our p. rettgeri pa with other known gram negative periplasmically located beta-lactam amidases. the analysis revealed a high homology with other enterobacteric amidases (60%-65%), while with similar pseudomonas sp. amidases the homology exceeded 25%. these homologies indicate their common ancestry.	1992	1472713
non-invasive thermometry using magnetic resonance diffusion imaging: potential for application in hyperthermic oncology.	the proposition to use non-invasive thermometry based on magnetic resonance diffusion imaging for applications in therapeutic hyperthermia is examined. the measurement of proton motion predominantly associated with the self-diffusion of water can be characterized by a boltzmann temperature dependence (i.e. e-ea/kt). the activation energy (ea) is on the order of 0.2 ev and, for a restricted range (approximately 30 degrees) at a base temperature of approximately 300 k, the relationship between the ...	2006	1479207
avoidance of endotoxin-induced inflammation during studies of albumin clearance from caprine joints.	intra-articular injection of radiolabelled, commercial goat serum albumin (gsa) produces acute arthritis in caprine joints. this inflammation distorts clearance values and vitiates studies of normal lymphatic function. endotoxin, routinely found in commercial albumin preparations, appears to cause this local reaction. we describe a simple method for the preparation of low-endotoxin, radioiodinated serum albumin from aseptically collected serum. we have used this technique to prepare gsa for use ...	1992	1489542
[antimicrobial activities of ceftazidime on fresh clinical isolates].	antimicrobial activity of ceftazidime (caz) was compared with those of other cephem antibiotics against clinically isolated strains sent to us by medical institutions throughout japan in 1989 and 1991. those strains separated and identified from samples collected from patients with various infections were also examined, and the following results were obtained. 1. the results suggested that, compared with reports of studies conducted with clinical isolates in early 1980's, mic90 of caz in 1991 we ...	1992	1494227
in vitro activity and beta-lactamase stability of ljc 10,627.	the in vitro activity of ljc 10,627, a new carbapenem, was compared with those of imipenem, cefotaxime, ceftazidime, and gentamicin. ljc 10,627 inhibited 90% of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, enterobacter aerogenes, enterobacter agglomerans, enterobacter cloacae, hafnia alvei, citrobacter freundii, citrobacter diversus, proteus mirabilis, morganella morganii, proteus rettgeri, serratia marcescens, pseudomonas cepacia, salmonellae, shigellae, aeromonas, and yersiniae ...	1992	1510436
correlations between laser flare measurements and anterior chamber protein concentrations.	the laser flare cell meter quantifies anterior chamber (ac) protein (flare) by measuring light scattering of a helium-neon laser beam in the ac. the relationship between photon count and protein concentration both in vitro and in vivo was assessed. the reproducibility of the in vitro photon count measurements was 7.3%. there was a significant linear relationship between photon count and the concentration of both albumin (r = 1.0, p = 0.0001) and immunoglobulin g (igg, r = 0.99, p = 0.0001) in vi ...	2006	1526738
pharmacokinetics and pharmacodynamics of subcutaneously administered u40 and u100 formulations of regular human insulin.	action profiles of 12 u of regular human insulin (actrapid hm) administered subcutaneously as a u40 or u100 formulation were studied. euglycaemic glucose clamps were performed on two separate days in 8 healthy subjects (basal i.v. insulin infusion 0.1 mu/kg/min, plasma glucose 5.0 mmol/l, mean +/- sd age 25 +/- 2 years, bmi 22.7 +/- 1.4 kg/m2). serum insulin concentrations increased after injection of u40 or u100 from similar baseline values to maximal individual concentrations of 305 +/- 79 vs. ...	1992	1563532
[an epidemiology of hypertension in japanese].		2006	1635191
imipenem- and meropenem-resistant mutants of enterobacter cloacae and proteus rettgeri lack porins.	carbapenems such as imipenem and meropenem are not rapidly hydrolyzed by commonly occurring beta-lactamases. nevertheless, it was possible, by mutagenesis and selection, to isolate mutant strains of enterobacter cloacae and proteus rettgeri that are highly resistant to meropenem and imipenem. two alterations were noted in the e. cloacae mutants. first, the mutant strains appeared to be strongly derepressed in the production of beta-lactamases, which reached a very high level when the strains wer ...	1991	1656855
monoclonal antibodies to quebec strain (q17) of bovine rotavirus.	fourteen monoclonal antibodies (mabs) against "quebec" strain (q17) of bovine rotavirus were isolated and characterized. four were specific for viral protein vp7 and ten were specific for viral protein vp6. five different isotypes were represented by this group of antibodies. all of the anti-vp6 and none of the anti-vp7 antibodies were sensitive to the effects of periodate on their antigen. the antibodies could be separated into three groups based on their relative resistance to the dissociation ...	1990	1698323
control cells for image cytometric dna analysis of esophageal tissue and the influence of preoperative treatment.	the nuclear dna content of 4,960 normal cells in 30 esophagectomy specimens was assessed by image cytometry. in relation to intermediate squamous epithelial cells, the mean transmission values were 25.6% higher for basal squamous epithelial cells, 10.1% higher for fibroblasts and 16.2% lower for lymphocytes. the interslide coefficient of variation (cv) was similar for intermediate and basal squamous epithelial cells, 20.2% and 18.9%, respectively, while fibroblasts and lymphocytes displayed lowe ...	2006	1698373
new trends in the preparation and storage of platelets.		2001	1731433
effect of blood transfusion on plasma selenium, glutathione peroxidase and manganese levels in very low birth weight infants.	very low birth weight infants often receive multiple blood transfusions. we measured the plasma levels of the trace elements selenium, manganese, and glutathione peroxidase in 20 very low birth weight infants prior to blood transfusion and then at 24, 48 and 72 h after transfusion. there was no detectable change in mean selenium or glutathione peroxidase concentrations after transfusion, but the mean (sd) plasma manganese increased from 3.8 (1.5) to 6.0 (2.3) micrograms/l at 72 h.	2006	1797115
effect of blood transfusion on plasma selenium, glutathione peroxidase and manganese levels in very low birth weight infants.	very low birth weight infants often receive multiple blood transfusions. we measured the plasma levels of the trace elements selenium, manganese, and glutathione peroxidase in 20 very low birth weight infants prior to blood transfusion and then at 24, 48 and 72 h after transfusion. there was no detectable change in mean selenium or glutathione peroxidase concentrations after transfusion, but the mean (sd) plasma manganese increased from 3.8 (1.5) to 6.0 (2.3) micrograms/l at 72 h.	2006	1797115
memory modulation by brain benzodiazepines.	1. recent evidence indicates that post-training memory processes are down-regulated by benzodiazepine/gaba-a systems in the amygdala, septum and hippocampus. habituation and avoidance learning are accompanied by a decrease of benzodiazepine-like immunoreactivity in the three structures, explainable by a release of benzodiazepines. immediate post-training microinjection of the benzodiazepine antagonist flumazenil into the hippocampus enhances retention of habituation. the post-training administra ...	1991	1797279
photoaffinity labeling of rat type i iodothyronine deiodinase.	the photoreactive compound p-nitrophenyl-2-diazo-3,3,3-trifluoropropionate (pal) was coupled to [125i]rt3, t4, or t3 and incubated with liver and kidney microsomes of hypo-, hyper-, or euthyroid rats to identify the type i iodothyronine deiodinase. various substrates or inhibitors of the enzyme, including rt3, t4, t3, 6-n-propylthiouracil (ptu), and iopanoic acid, were used as competitors to establish the specificity of protein labeling. the pal derivatization enhanced the behavior of t4 and t3 ...	1991	1855452
tenth international meeting on n-nitroso compounds, mycotoxins and tobacco smoke: relevance to human cancer.		1991	1855829
can't find one aids vaccine? try for a few!		2006	1865511
can't find one aids vaccine? try for a few!		2006	1865511
in vitro and in vivo evaluation of ro 09-1428, a new parenteral cephalosporin with high antipseudomonal activity.	ro 09-1428, a new parenteral cephalosporin with a catechol moiety attached at position 7 of the cephalosporin ring, showed high in vitro activity against escherichia coli, klebsiella pneumoniae, proteus mirabilis, proteus vulgaris, and streptococcus pyogenes, with mics for 90% of strains tested (mic90s) of less than or equal to 0.39 micrograms/ml. morganella morganii, providencia rettgeri, citrobacter freundii, haemophilus influenzae, staphylococcus aureus, and streptococcus pneumoniae were inhi ...	1991	1906261
biosynthesis of isochorismate in klebsiella pneumoniae: origin of o-2.	the shikimate metabolites are key precursors to a large number of natural products, including aromatic amino acids. chorismic acid is an important branch point in the biosynthetic pathway to aromatic amino acids. chorismic acid is also unique among natural products since it is the only compound known to undergo an enzymatic claisen rearrangement. a metabolite of chorismic acid, isochorismic acid, first observed in aerobacter aerogenes differs in its chemical structure by the location of the hydr ...	1991	1913340
coronary vasospasm as a potential cause of myocardial infarction and paroxysmal atrial fibrillation in a relatively young woman.	vasospasm-related myocardial infarction in young women with normal coronary arteries has infrequently been reported and vasospasm-related paroxysmal atrial fibrillation (paf) has rarely been described. we present a 33-year-old woman with old inferior myocardial infarction and postinfarction angina at rest; the angina was accompanied by paf and electrocardiographic st-segment elevation in the inferior leads. coronary angiography revealed normal coronary arteries and intracoronary acetylcholine pr ...	2007	1914277
isolation and characterization of a pea catalase cdna.		2007	1932700
closure of craniofacial defects after cancer resection.	resection of malignancies of the upper face and skull base may result in complex bone and soft tissue defects. to better define the optimal management of these defects, we conducted a retrospective review of 75 consecutive patients who underwent closure of 76 craniofacial defects after malignant tumor excision from 1966 to 1990. wound complications requiring further surgery occurred in 30% of the defects (23 of 76). wound complications at anterior, temporal, or combined sites were correlated wit ...	2007	1951900
[antibiotic sensitivity of bacteria isolated from patients at 6 hospitals in osaka].	we examined mics of 6 oral new quinolones and 4 oral cephems against bacteria isolated from patients at 6 hospitals in osaka during the period from january to june in 1990, and the following results were obtained. 1. all species excluding streptococcus pyogenes were more sensitive with less frequencies of resistance to new quinolones than to cephems. in new quinolones, tosufloxacin (tflx) was the most active against gram-positive cocci and ciprofloxacin (cpfx) and tflx had the highest activities ...	1991	1960855
oviposition by screwworm flies (diptera: calliphoridae) on contact with host fluids.	factor affecting oviposition by screwworm flies, cochliomyia hominivorax (coquerel), contacting different host fluids were examined in a laboratory bioassay. fresh bovine blood, which does not release the attractive odors involved in host finding, nevertheless stimulated as many or more females to oviposit than did the other fluids tested. these other fluids included attractive fluid from screwworm-infected wounds (a favored oviposition site in nature) and cultures of providencia rettgeri (a bac ...	1991	2019681
aerobic bacteria from nasal discharge of goats suffering from clinical ppr: isolation and identification.	bacteriological isolation of aerobic bacteria from nasal discharge of achondroplastic west african dwarf goats showing clinical signs of peste des petits ruminants (ppr), and the laboratory procedures carried out for the identification of the isolates are described. from a total of forty nasal swabs obtained seventy five isolates were recovered. the percentage frequency of isolation of different organisms in descending order of occurrence is as follows: staphylococcus 44.0%; streptococcus 22.67% ...	1991	2023545
[antimicrobial susceptibilities of clinical isolates of morganella-proteus-providencia group of bacteria].	we examined in vitro susceptibilities of 3,109 isolates belonging to 5 species of proteeae to 2 penicillins, 5 cephems and 2 aminoglycosides. the isolates were collected from 69 hospital laboratories throughout japan between 1986 and 1988. minimal inhibitory concentrations were determined using the agar dilution method with inoculation of 10(8) cells/ml of bacteria. proteus mirabilis had marked susceptibilities to the penicillins and cephems tested. proteus vulgaris and morganella morganii were ...	1991	2041155
biochemical considerations regarding cellular regulation through messenger and allosteric systems. antagonism between catabolic oxidation of free fatty acids and anabolic aerobic glycolysis in the liver.	this theoretic study deals with some biochemical considerations 1) of a general nature, on cellular regulation both by the messenger systems: type a and type c (ms-a & ms-c) and by the allosteric system, and 2) of a special nature, taking into account, for example, the antagonism between the catabolic oxidation of free fatty acids (ffa) and anabolic aerobic glycolysis, as a major mechanism of allosteric short-term regulation of glycemic homeostasis. the discussion at molecular level is facilitat ...	1990	2080418
[susceptibilities of clinical bacterial isolates to antimicrobial agents. a study mainly focused on imipenem. research group for testing imipenem susceptibility on clinical isolates].	we investigated susceptibilities of clinical bacterial isolates to imipenem (ipm) and other antimicrobial agents at 459 hospital laboratories throughout japan from september to december of 1988. in this study, identification and susceptibility testing were performed at each hospital laboratory and the tests were carried out according to the 1-dilution or 3-dilution disc technique in which susceptibilities are classified into 4 grades: , ++, + and -. ipm had significantly high activity against st ...	1990	2086814
biological characterization of a new radioactive labeling reagent for bacterial penicillin-binding proteins.	radiolabeled penicillin g is widely used as the imaging agent in penicillin-binding protein (pbp) assays. the disadvantages of most forms of labeled penicillin g are instability on storage and the long exposure times usually required for autoradiography or fluorography of electrophoretic gels. we investigated the utility of radioiodinated penicillin v as an alternative reagent. radioiodination of p-(trimethylstannyl)penicillin v with [125i]na, using a modification of the chloramine-t method, is ...	1990	2113792
in-vitro and in-vivo antibacterial activities of e1040, a new cephalosporin with potent antipseudomonal activity.	e1040 is a new parenteral cephalosporin with a broad antibacterial spectrum and potent activity against gram-negative bacteria including pseudomonas aeruginosa. the in-vitro activities of e1040 against clinical isolates of enterobacter cloacae, ent. aerogenes, providencia rettgeri, and morganella morganii were superior to those of ceftazidime, cefoperazone, cefmenoxime, and cefuzonam. the activities of e1040 against gram-positive cocci were comparable with those of ceftazidime, but it was less a ...	1990	2127928
binding of the bovine basic pancreatic trypsin inhibitor (kunitz) to human glu1-, lys77-, val442-, and val561-plasmin: a comparative study.	thermodynamic and kinetic parameters for the binding of the bovine basic pancreatic trypsin inhibitor (bpti, kunitz inhibitor) to human glu1-, lys77-, val442- and val561-plasmin (ec 3.4.21.7) have been determined between ph 3.0 and 9.5, and from 5.0 to 45.0 degrees c. the inhibitor-binding properties to human glu1-, lys77-, val442- and val561-plasmin suggest a possible role of bpti in modulating plasmin activity when the inhibitor is used therapeutically.	1990	2143086
[current status and perspectives of bioethics in argentina].	the study of bioethics in argentina owes much to the efforts of josé alberto mainetti, who in 1972 founded the institute of medical humanities, devoted to researching, teaching, and publicizing the discipline. because of growing interest in the field of bioethics, a bioethics center was created in the institute in 1987 and it has stimulated the organization of several groups in various provinces in the country. one of the most important of them, located at the national university of mar del plat ...	1999	2144132
inactivation of legionella pneumophila by monochloramine.	chloramination which is used in south australia to control the growth of naegleria fowleri, was investigated to see if it would also control that of legionella pneumophila. it was found that l. pneumophila was more sensitive than escherichia coli to monochloramine. at 1.0 mg/l, a 99% kill of l. pneumophila was achieved in 15 min compared with 37 min for a 99% kill of e. coli. combined with the stability of monochloramine, even at elevated temperatures, the results suggest that this disinfectant ...	1990	2196255
personal power: your key to success.		2007	2216083
"come south, young doctor", humana tells canadian mds.		2007	2224721
influence of temperature on beta-lactamase production and outer membrane proteins in gram-negative rods.	the influence of temperature (ranging from 28 to 42 degrees c) was studied on the phenotypic expression of chromosomally mediated beta-lactamases in gram-negative clinical isolates and in their beta-lactamase-depressed resistant counterparts. the enzymes were expressed most intensely at lower temperatures (28 or 32 degrees c). in most strains the enzyme was barely detectable at growth temperatures of 42 degrees c independent of the inducer employed. the release of the enzyme into the surrounding ...	1990	2253497
[bacterial flora of the oral cavity, fangs and venom of bothrops jararaca: possible source of infection at the site of bite].	culture of fang, fang sheath and venom of fifteen healthy freshly captured bothrops jararaca were analyzed. the bacteria most frequently encountered were group d streptococci (12 snakes), enterobacter sp. (6), providencia rettgeri (6), providencia sp. (4), escherichia coli (4), morganella morganii (3) and clostridium sp. (5). the bacteria observed are similar to those found in the abscesses from bothrops bitten patients. since these snake mouth bacteria may be inoculated during the snake bite, b ...	1990	2259834
additive interaction between tamoxifen and rifampicin in human biliary tract carcinoma cells.	a novel two-drug combination of tamoxifen and rifampicin has been investigated for the treatment of biliary tract-associated malignancies. their effects, alone and in combination, on human tumour cells were studied using two pancreatic carcinoma cell lines. mia paca-2 and aspc-1, and a gall bladder carcinoma cell line, g-415. inhibition of growth was used as an endpoint. the cells differed in sensitivity to equimolar doses of the two drugs given as single agents. combined doses of rifampicin and ...	1990	2265416
[susceptibilities of clinical bacterial isolates to antimicrobial agents. a study mainly focused on imipenem. reported by the research group for testing imipenem susceptibility on clinical isolates].	this study was conducted to investigate susceptibilities of clinical bacterial isolates to imipenem (ipm) and other antibacterial agents at 64 hospital laboratories throughout japan from september to december of 1988. in this study, identification and susceptibility testing were carried out at each laboratory and the tests were performed according to the disk dilution method recommended by nccls in which susceptibilities are classified into "s", "ms", "i" and "r". ipm showed markedly high in vit ...	1990	2287060
chronic granulocytic leukaemia presenting with mandibular mass.	a case of chronic granulocytic leukaemia with extramedullary deposits in the mandible is reported. systemic chemotherapy coupled with local irradiation resulted in regression of the mandibular mass.	2008	2292564
correlation between essential tremor and migraine headache.	the relationship between essential tremor (et) and migraine was investigated in a prospective study. in a group of 74 et patients 36.5% had migraine compared with 17.7% of 102 control subjects without tremor. in a group of 58 patients with migraine 17.2% had et compared with 1.2% of 85 controls without migraine. the prevalence of et in migraine controls was greater than controls without migraine (22% compared with 1%; p = 0.002). it is concluded that there is an association between essential tre ...	2008	2292698
morganella morganii urease: purification, characterization, and isolation of gene sequences.	morganella morganii, a very common cause of catheter-associated bacteriuria, was previously classified with the genus proteus on the basis of urease production. m. morganii constitutively synthesizes a urease distinct from that of other uropathogens. the enzyme, purified 175-fold by passage through deae-sepharose, phenyl-sepharose, mono-q, and superose 6 chromatography resins, was found to have a native molecular size of 590 kilodaltons and was composed of three distinct subunits with apparent m ...	1990	2345135
actin gene expression in murine erythroleukemia cells treated with cytochalasin d.	the expression of cytoskeletal protein genes may be linked to both cell growth and the status of the cytoskeleton. actin gene expression was examined in murine erythroleukemia cells treated with the microfilament disrupting agent, cytochalasin d (cd), at a concentration which was determined to inhibit cell growth and arrest cells in the s and g1 phase of the cell cycle. levels of actin mrna and protein synthesis were elevated eight- and sixfold, respectively, after 9 h in cd. this increase was r ...	2008	2347376
the sugar moiety of bovine s-antigen.	to obtain insight into the glycoprotein nature of s-antigen (s-ag), we have investigated the affinity of bovine s-ag for plant lectins, location of the sugar moiety within the molecule, and incorporation of radiolabelled mannose and glucosamine into s-ag. it was found (i) that only about 10% of purified s-ag was bound to concanavalin a (con a) and wheat germ agglutinin (wga) columns, (ii) that both concanavalin a and wheat germ agglutinin bound chymotryptic peptides derived from the c-terminal h ...	1990	2384003
participation, decision making, and job stress.		2008	2395036
mandibular metastasis from a cerebellar medulloblastoma.		2008	2395054
[reactivity to bacterial peptidoglycans in a phagocytosis system. the range of immunological specificity of escherichia coli peptidoglycan].	the antigenic specificity of e. coli m17 peptidoglycans (pg) was studied in the test system based on the stimulation of neutrophils with pg opsonized with the whole and exhausted igg fraction of human serum. within the generic taxon, the pg under study were similar in their antigenic properties. the opsonic activity of igg exhausted with the preparations of different e. coli strains decreased by 93.2-95.8%. an essential difference of e. coli pg from similar components of other representatives of ...	1985	2413663
[antigenic characteristics of standard strains of providencia rettgeri (o- and h-antigens)].	additions and changes have been introduced into the existing antigenic diagnostic scheme of p. rettgeri on the basis of the study of the antigenic structure of standard strains from foreign collections: new, formerly unknown varieties of somatic and flagellar antigens (o35, o36, h27, h28) have been discovered, the complex of antigenic factors for h-antigens 7, 10, 23, 27 has been discovered. strains 958 (36 : 28) and 979 (16 : 27a, 23b, 2a), previously classified with the genus morganella, have ...	1985	2416153
sequence of myosin-crossreactive epitopes of streptococcal m protein.	group a streptococcal m proteins contain epitopes that crossreact with sarcolemmal membrane proteins of human myocardium and myosin. in the present study, synthetic peptide copies spanning the entire 197-residue pepsin extracted fragment of type 5 m protein were used to localize the myosin-crossreactive epitopes of the molecule. peptide 84-116 inhibited by 75% the binding of myosin-crossreactive antibodies evoked by pep m5, as determined by elisa. immunoblot inhibition studies confirmed that pep ...	1986	2430047
[determination of the molecular weight of microbial polysaccharides using high performance exclusion chromatography].	an automatic method of determining the molecular weight parameters (mw, mn) of microbial polysaccharides such as dextran, pullulan was developed based on the use of high performance size-exclusion chromatography on the two types of columns: zorbax psm 60 + 300 + 1000 and synchropack gpc 100 + 500 + 1000. the mw and mn values were determined for a number of domestic and foreign dextran preparations. changes in the molecular weight of pullulan and hydroxyethylstarch resulted from acid and enzymati ...	2008	2443909
boxing and the brain.		2008	2493277
in vitro antibacterial properties of cefetamet and in vivo activity of its orally absorbable ester derivative, cefetamet pivoxil.	the in vitro activity of cefetamet, the microbiologically active metabolite of the orally administered prodrug cefetamet pivoxil, was compared with that of cephalexin, cefaclor, cefuroxime and amoxicillin. cefetamet was highly active against enterobacteriaceae, neisseria spp., vibrio spp., haemophilus influenzae and streptococci other than enterococci. cefetamet inhibited cefaclor-resistant species such as proteus vulgaris, providencia stuartii, providencia rettgeri and serratia marcescens. stap ...	1989	2504597
[superoxide dismutase overcomes 2-cell block in mouse embryos].		1989	2504849
dactimicin, a new aminoglycoside: in vitro activity, post-antibiotic effect and interaction with other antibiotics.	the in vitro activity of the new aminoglycoside dactimicin in comparison to amikacin was tested alone and in combination with piperacillin, mezlocillin and ceftazidime against freshly isolated clinical pathogens. dactimicin was more active than amikacin against enterobacter cloacae, providencia rettgeri and salmonella spp., and less active than amikacin against escherichia coli, pseudomonas aeruginosa and acinetobacter anitratus. using the checkerboard technique, the combination of either dactim ...	1989	2506028
sequences that promote formation of catenated intertwines during termination of dna replication.	the normal sequence at which sv40 dna replication terminates (ter) is unusual in that it promotes formation of catenated intertwines when two converging replication forks enter to complete replication (weaver et al., 1985). here we show that yeast centromeric sequences also exhibit this phenomenon. cen3 caused accumulation of late replicating intermediates and catenated dimers in plasmids replicating in mammalian cells, but only when it was located in the termination region (180 degrees from ori ...	1989	2542894
cloning and characterization of the acyl-coenzyme a: 6-aminopenicillanic-acid-acyltransferase gene of penicillium chrysogenum.	a gene, aat, encoding acyl-coa: 6-aminopenicillanic acid acyltransferase (aat), the last enzyme of the penicillin (pn) biosynthetic pathway, has been cloned from the genome of penicillium chrysogenum as-p-78. the gene contains three introns in the 5'-region and encodes a protein of 357 amino acids with an mr of 39,943. it complements mutants of p. chrysogenum deficient in aat activity. the aat gene is expressed as a 1.15-kb transcript and the encoded protein appears to be processed post-translat ...	1989	2555269
usefulness of trehalose fermentation and l-glutamic acid decarboxylation for identification of biochemically aberrant providencia stuartii strains.	a total of 849 providencia isolates were collected during a 4-year period when an increased incidence of nosocomial providencia stuartii infection was noted in urologic wards. of these isolates, 630 were identified as p. stuartii, 206 were identified as providencia rettgeri, and 1 was identified as providencia alcalifaciens. twelve inositol-positive isolates from 10 patients (10 strains) resembled p. stuartii in fermenting trehalose but resembled p. rettgeri in fermenting d-arabitol or meso-eryt ...	1989	2570791
the pharmacology of segmental transmission in the spinal cord.		2008	2573110
classification of tick-borne flaviviruses.		2008	2576589
numerical analysis of electrophoretic protein patterns of providencia rettgeri strains from human faeces, urine and other specimens.	thirty-one strains of providencia rettgeri (mainly from humans) were characterized by one-dimensional sds-page of cellular proteins. the strains came from various countries and comprised 14 from urine, eight from faeces, two from bile (plus one from the liver of a sheep), two from sputum, one from an insect pupa and three the sources of which were unknown. also included, for reference purposes, were the type strains of the four other providencia species. the protein patterns, which contained 45- ...	1989	2584173
the leukaemia research fund data collection survey: the incidence and geographical distribution of acute myeloid leukemia.	this paper reports on the 2,362 cases of acute myeloid leukemia (aml) accumulated by the leukaemia research fund data collection survey between january 1, 1984, and june 30, 1988 providing the recent geographical distribution and descriptive epidemiology of the aml group of conditions. statistical approaches to this data set are described. the study shows sex differences in distribution for those aged under 55 years compared to older age groups, with variable male: female incidence in different ...	2007	2586181
evaluation of stuart's transport medium containing penicillinase. an in vitro study. brief report.	an in vitro study was performed to evaluate the value of penicillinase in stuart's transport medium. swabs were taken from serum broth cultures of staphylococcus aureus, escherichia coli and proteus rettgeri, incubated with cefuroxime. following 24 hours' storage in the transport medium, the recovery of p. rettgeri was significantly higher from stuart's transport media containing penicillinase in a concentration of 100,000 units/ml, than from swabs stored in stuart's medium without penicillinase ...	1989	2590536
the influence of semantic and perceptual factors on lexical comprehension in aphasic and right brain-damaged patients.	we investigated whether the errors made by aphasic patients and right brain-damaged (rbd) patients on a word-picture matching test were differently related to the semantic and perceptual difficulties of the task. to this effect, the target picture was presented in one condition along with two semantically similar distractors, in another condition with two perceptually similar distractors, and in a third condition with two distractors that were both semantically and perceptually similar. there we ...	2008	2612178
the influence of semantic and perceptual factors on lexical comprehension in aphasic and right brain-damaged patients.	we investigated whether the errors made by aphasic patients and right brain-damaged (rbd) patients on a word-picture matching test were differently related to the semantic and perceptual difficulties of the task. to this effect, the target picture was presented in one condition along with two semantically similar distractors, in another condition with two perceptually similar distractors, and in a third condition with two distractors that were both semantically and perceptually similar. there we ...	2008	2612178
gas liquid chromatography of amines produced by the enterobacteriaceae.	1. gas liquid chromatography (glc) was used to test the production of amines by 85 strains of enterobacteriaceae. 2. the strains tested produced cadaverine, beta-phenylethylamine, putrescine, iso-amylamine, 2-methylbutylamine and iso-butylamine. 3. although the overlap in amine production between obviously different genera and species limits the general applicability of this methodology in clinical microbiology, the results obtained demonstrate the possibility of differentiating proteus rettgeri ...	1989	2620174
[subungual malignant melanoma--30 year review of cases].	twenty-five patients with subungual malignant melanoma confirmed by pathology from 1958 to 1987 were reported. there were 19 males and 6 females. 76% of the lesions occurred on the finger and 24% on the foot. the most common site was the thumb or great toe. 16/25 of the patients had history of subungual pigmented streaks. as trauma at the lesion site might initiate subungual melanoma (28%), doctors should pay close attention to the subungual black pigmented streaks or a mass below the nail with ...	2009	2620637
complications of intracranial bypass for vertebrobasilar insufficiency.	the authors' initial experience with intracranial revascularization of vertebrobasilar insufficiency, reported previously, fortunately yielded reasonably good results with high patency rates but in some cases there were significant, albeit temporary, complications. since that time, major brain-stem strokes have occurred in two patients following superficial temporal to superior cerebellar artery bypass procedures. this occurrence has caused the authors to reassess their experience with this proc ...	2008	2643687
complications of intracranial bypass for vertebrobasilar insufficiency.	the authors' initial experience with intracranial revascularization of vertebrobasilar insufficiency, reported previously, fortunately yielded reasonably good results with high patency rates but in some cases there were significant, albeit temporary, complications. since that time, major brain-stem strokes have occurred in two patients following superficial temporal to superior cerebellar artery bypass procedures. this occurrence has caused the authors to reassess their experience with this proc ...	2008	2643687
neu-laxova syndrome: pathological, radiological, and prenatal findings in a stillborn female.	we describe a case of neu-laxova syndrome in a stillborn female. she was born at 41 weeks of gestation to consanguineous italian parents, who had had 2 previous stillborn offspring. pathological, radiological, and prenatal studies are reported.	2008	2650548
[factors in therapeutic decisions].		2009	2652061
sonographic evaluation of superior mesenteric vascular relationship in malrotation.	we report sonographic demonstration of abnormal and characteristic superior mesenteric vascular anatomy in three cases of surgically proved intestinal malrotation. sonographic screening examinations of children with abdominal pain should include an evaluation of the superior mesenteric vessels.	2009	2654854
platelet function, platelet prostanoids and vascular prostacyclin in diabetes mellitus.		2009	2654960
purification and characterization of lipoprotein lipase and hepatic triglyceride lipase from human postheparin plasma: production of monospecific antibody to the individual lipase.	lipoprotein lipase (lpl) and hepatic triglyceride lipase (htgl) were purified to homogeneity from human postheparin plasma. molecular, catalytic and immunological properties of the purified enzymes were investigated. the native molecular weights of lpl and htgl were 67,200 and 65,500, respectively, by gel chromatography. the subunit molecular weights of lpl and htgl were 60,600 and 64,600, respectively, suggesting that these enzymes are catalytically active in a monomeric form. in addition, the ...	1989	2663075
comparison of the in vitro and in vivo antibacterial activities of cefepime (bmy-28142) with ceftazidime, cefuzonam, cefotaxime and cefmenoxime.	cefepime (bmy-28142), a new semisynthetic cephalosporin, was evaluated for in vitro and in vivo antibacterial activities in comparison with ceftazidime, cefuzonam, cefotaxime and cefmenoxime. cefepime showed a well-balanced, broad spectrum of activity against a number of clinical isolates collected in japan. the activity of cefepime against gram-positive bacteria was several times greater than that of ceftazidime, nearly comparable to cefotaxime and cefmenoxime, and slightly weaker than cefuzona ...	1989	2663406
the neural basis of reward and reinforcement: a conference in honour of peter m. milner. november 18-21, 1988. proceedings.		2008	2682405
influence of zofenopril and low doses of hydrochlorothiazide on plasma lipoproteins in patients with mild to moderate essential hypertension.	the effects of zofenopril (zof) calcium, an anticonverting enzyme inhibitor, and of hydrochlorothiazide (hct) on plasma lipids, lipoproteins and apoproteins were compared in 37 patients with sitting diastolic blood pressure (sdbp) of 95 to 110 mm hg at the end of a placebo period of 4 weeks. in the randomized double-blind experiment, 16 males and 21 females were treated with either zof, 30 mg (n = 18) or hct, 25 mg (n = 19), once daily. when a sdbp of less than 90 mm hg was not reached after 4 w ...	2009	2686713
mutations affecting regulation of cobinamide biosynthesis in salmonella typhimurium.	transcription of the genes for cobalamin biosynthesis is reduced during aerobic growth. we isolated and characterized mutants that showed a 2- to 90-fold increase in aerobic expression of the cobinamide biosynthesis (cobi) genes, depending on the particular mutation and growth conditions. four different classes of mutations were characterized. all mutations (cobri through cobriv) were cis-acting, dominant mutations that mapped near the promoter end of the cobi operon. two of these classes of mut ...	1989	2687248
[evaluation of the effectiveness of cytoprotective drugs in the treatment of duodenal ulcer].		2009	2697093
determination of stereo- and positional isomers of oxygenated triterpenoids by reversed phase high performance liquid chromatography.	twenty four oxygenated triterpenoids, including eight pairs of stereoisomers and five pairs of positional isomers, could be separated by reversed phase hplc. the capacity factors obtained in methanol-water and acetonitrile-water solvent systems made it possible to correlate the molecular polarities due to the presence of multiple oxygenated functional groups in these compounds. it was found that the number and position of functional groups as well as the stereochemistry of these functional group ...	2009	2715731
pilomatrix carcinoma: role played by mr imaging.	we report the magnetic resonance imaging (mri) of a pilomatrix carcinoma. we found a soft tissue tumor of the back entering the spinal canal and compressing the spinal cord and we monitored a good response to radiotherapy and chemotherapy. we have concluded that mri played an important role in determination of the volume, extension and management of this rare malignant tumor.	2009	2747902
antibody responses and protection in mice immunized with herpes simplex virus type 1 antigen immune-stimulating complex preparations.	the formation of immune-stimulating complexes (iscoms) obtained by mixing the glycoside quil a with an antigen preparation derived from herpes simplex virus type 1 (hsv-1)-infected cell cultures using a zwitterionic detergent is described. the hsv-1 antigen preparation incorporated into iscoms elicited significantly greater antibody responses in mice than the same preparation administered together with aluminium hydroxide gel, and provided complete protection against hsv-1 or hsv-2 lethal, syste ...	1989	2769234
career options of occupational physicians.		2009	2769461
[vasculitis-aids. a fortuitous association?].		2009	2772308
[cardiovascular risk factors in children and adolescents in fuenlabrada: objectives, features of the population, design, participation, equipment, laboratory technics, and quality control].	fuenlabrada is at the present time the most industrialized town placed at the south are of madrid. this population has some peculiar attractive characteristics from the epidemiologic point of view. perhaps the most important is that the majority of its inhabitants are immigrant from other depressed rural areas of the country, with a low socio-economic and cultural level. the new conditions of life could have changed the life expectation and the causes of morbidity and mortality of this populatio ...	1989	2772364
regional histochemical aspects of xanthine oxidase activity in ischemic and reperfused small intestine of the rat.	the study describes regional changes of xanthine oxidase and succinate dehydrogenase activities as shown by the ischemic and reperfused small intestine of the rat. the results are obtained with enzyme histochemical methods, including densitometrical verifications, and are substantiated with biochemical enzyme determinations. the decrease of xanthine oxidase activity was best visible in the anoxic duodenum and jejunum, where the findings of histochemical enzyme determinations agreed with those ac ...	1989	2776176
induction potency of various beta-lactam derivatives in gram-negative rods.	the induction potency of various beta-lactams as well as that of 'nonspecific' inducers such as the media employed or body fluids were studied in gram-negative clinical isolates and in their resistant corresponding counterparts. in all wild-type isolates quite a few beta-lactams (mainly cefoxitin and imipenem) shared the ability to induce the chromosomal beta-lactamase, whereas all beta-lactams - including 6-aps and 7-cps clavulanic acid, and sulbactam (both beta-lactamase inhibitors), exhibited ...	1989	2785904
two cases of pneumocystis carinii pneumonia occurred in human immunodeficiency virus infected patients: supplemental treatment with aerosolised pentamidine isethionate.	two cases of pneumocystis carinii pneumonia occurred in human immunodeficiency virus infected patients who were diagnosed by the aspiration-lung-biopsy. they were treated with 4 mg/kg of pentamidine isethionate intravenously administered followed by pentamidine aerosol inhalation. although clinical and laboratory findings were improved by the fifth or seventh day of intravenous therapy, substantial leukocytopenia, from 3,000/cmm to 600/cmm and from 2,700/cmm to 1,000/cmm, occurred. at this point ...	1989	2786100