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molecular diagnostics of arthroconidial yeasts, frequent pulmonary opportunists.magnusiomyces capitatusandsaprochaete clavataare members of the clade of arthroconidial yeasts that represent emerging opportunistic pulmonary pathogens in immunocompromised patients. given that standard ribosomal dna (rdna) identification often provides confusing results, in this study, we analyzed 34 isolates with the goal of finding new genetic markers for classification using multilocus sequencing and amplified fragment length polymorphism (aflp). the interspecific similarity obtained using ...201829070656
magnusiomyces capitatus peritonitis in a child with acute lymphocytic leukemia as a breakthrough infection during caspofungin therapy.magnusiomyces capitatus is an emerging opportunistic fungal pathogen particularly in immunocompromised patients. we report a case of a m. capitatus peritonitis in child with acute lymphocytic leukemia as a breakthrough infection during caspofungin therapy. the possibility of breakthrough infections caused by m. capitatus must be taken into consideration, particularly in immunosupressed patients being treated for systemic fungal infections by caspofungin. although there are no defined breakpoints ...201729145348
magnusiomyces capitatus: a new and emerging pathogen linked to keratomycosis.we describe our experience managing a case of fungal keratitis in a 71-year-old immunocompetent woman. intracameral cultures isolatedmagnusiomyces capitatus, a dimorphic commensal microbe with limited pathogenicity, in an immune competent patient. repeated corneal cultures for bacteria and fungus were negative. initial broad-spectrum topical fortified antibiotics were eventually escalated to include topical natamycin and voriconazole and oral voriconazole. the patient underwent emergent corneal ...201729162991
[role of surgery in saprochaete capitata (s. capitata) sepsis in a patient with acute myeloid leukemia].saprochaete capitata (s. capitata) fungal sepsis is a severe condition with a clinical presentation that is similar to other yeast originated fungal sepsis. it is observed in patients with hematological malignancies such as acute myeloid leukemia and neutropenia. we report a 23 year old male presenting with cough, fever and malaise. a bone marrow biopsy led to the diagnosis of acute myeloid leukemia. during the first cycle of chemotherapy the patient presented fever: blood cultures were positive ...201729189866
blastoschizomyces capitatus pulmonary infections in immunocompetent patients: case report, case series and literature review.blastoschizomyces capitatus is an uncommon opportunistic yeast associated with infections in neutropaenic patients secondary to haematological malignancies, with a special predilection for the lungs. globalisation and population migration impact on the epidemiology of infection with this organism but its effect on the immunocompetent population has rarely been described. we present here a case report, an overview of 11 other cases published between 2000 and 2016, and a comprehensive literature r ...201829198203
isolation of the rare opportunistic yeastsaprochaete capitatafrom clinical samples-experience from a tertiary care hospital in southern india and a brief review of the literature.saprochaete capitata(teleomorph:magnusiomyces capitatus) is a ubiquitous yeast found in environmental sources such as soil, water, air, plants and dairy products. it is also a part of the normal microbial flora in humans. the yeast is being increasingly reported as an opportunistic pathogen, especially in patients in the haemato-oncology setting, the infection being often mistakenly diagnosed as invasive candidiasis.201729207709
breakthrough saprochaete capitata infections among patients with hematological malignancies. 201729214882
sequencing offkshot spot 1 from saprochaete capitata to search for a relationship to reduced echinocandin susceptibility.saprochaete capitata, formerly known asgeotrichum capitatum, is an emerging fungal pathogen with low susceptibility to echinocandins. here, we report the nucleotide sequence of thes. capitatahot spot 1 region of thefksgene (fkshs1), which codifies for the catalytic subunit of β-1,3-d-glucan synthase, the target of echinocandins. for that purpose, we first designed degenerated oligonucleotide primers derived from conserved flanking regions of thefks1hs1 segment of 12 different fungal species. int ...201829229638
identification of uncommon oral yeasts from cancer patients by maldi-tof mass spectrometry.opportunistic infections due to candida species occur frequently in cancer patients because of their inherent immunosuppression. the aim of the present study was to investigate the epidemiology of yeast species from the oral cavity of patients during treatment for oncological and haematological malignancies.201829310582
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