Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| causes of death of hiv-infected persons in ottawa, ontario, 1984-1995. | acquired immunodeficiency syndrome (aids) has become a leading cause of death of young men in the united states. with the introduction of prophylaxes and antiretrovirals for opportunistic infection, there have been significant changes in the clinical history of human immunodeficiency virus (hiv) infection. | 1997 | 9382662 |
| low dietary fiber and high protein intakes associated with newly diagnosed diabetes in a remote aboriginal community. | the high prevalence of diabetes mellitus in north american aboriginal populations may be due to recent changes in lifestyle, including the adoption of a high-fat, low-fiber diet. to determine whether fat or fiber intakes were associated with new cases of diabetes, we studied 72% (728/1018) of residents aged > 9 y from a remote aboriginal community in northern ontario using the 75-g oral-glucose-tolerance test and 24-h dietary recall. the mean fat intake of this population (36% of energy) was typ ... | 1997 | 9394701 |
| hepatitis a outbreak in a socially-contained religious community in rural southern ontario. | 1997 | 9397602 | |
| common genomic variation in the apoc3 promoter associated with variation in plasma lipoproteins. | we hypothesized that common genomic variation that affected the expression and/or function of the products of the apoc3, apoe, fabp2, and pon1 genes would be associated with variation in biochemical phenotypes in a previously unstudied human sample. we determined genotypes of functional genomic variants of apoc3, apoe, fabp2, and pon1 in 509 adult aboriginal canadians from an isolated community in northern ontario. we tested for genotype associations with plasma lipoprotein traits. we found that ... | 1997 | 9409252 |
| outbreak of influenza a in an ontario nursing home--january 1997. | 1997 | 9439036 | |
| two quantitative methods for rib seriation in human skeletal remains. | accurate rib sequencing is of importance to both forensic anthropologists and human osteologists, but until recently there have been few traits used to aid in the seriation of ribs within a human burial. this study examines two measurements (head to tubercle length and superior costotransverse ligament crest height) for the purpose of aiding rib identification and seriation in human skeletal remains. a sample of 344 ribs from 43 individuals from the 19th century anglican church cemetery of st. t ... | 1998 | 9456539 |
| provision of preventive care to unannounced standardized patients. | to examine the relation between physician, training and practice characteristics and the provision of preventive care as described in the guidelines of the canadian task force on the periodic health examination. | 1998 | 9469139 |
| what factors influence primary care physicians' charges for their services? an exploratory study using standardized patients. | to determine the extent of variation in physicians' charges for health care encounters with unannounced standardized patients and factors associated with the variation. | 1998 | 9469140 |
| the right of dentists to take extra precautions when treating patients known to carry the human immunodeficiency virus. | oral health care providers have taken various positions toward the concept of correct behavior toward and management of patients who are seropositive for human immunodeficiency virus. several tribunal judgments and articles have discussed and analyzed this subject. this article presents a new detailed report and analysis and decision issued by a dental profession panel (tribunal) in ontario, canada. the concepts of universal precautions and antidiscriminatory acts are discussed. | 1997 | 9477869 |
| etiology of acute childhood encephalitis at the hospital for sick children, toronto, 1994-1995. | of 145 patients admitted to our hospital because of encephalitis-like illness, 50 patients hospitalized for > or =72 hours underwent standardized microbiological investigations. a confirmed or probable etiologic agent was identified in 20 cases (40%), including mycoplasma pneumoniae (9 cases). m. pneumoniae and enterovirus (2), herpes simplex virus (4), epstein-barr virus (1), human herpes-virus 6 (hhv-6) (1), hhv-6 and influenza virus type a (1), influenza virus type a (1), and powassan virus ( ... | 1998 | 9502462 |
| case costing means, measuring and managing now! the journey traveled by a community hospital. | funding for health care in ontario is moving from global funding to equity funding. in the future, hospitals will be reimbursed for how efficiently they care for their various patient populations. the ontario case costing project (occp) was a joint venture by the ontario hospital association and the ministry of health. incentive for participation in this project was based on the need to assess efficiencies in caring for patient populations in surgical suites and to obtain canadian data. case cos ... | 1997 | 9526309 |
| the economic costs of illicit drug use in ontario, 1992. | the use of illicit drugs causes health and social problems which imply economic costs to society. this paper uses the cost-of-illness method, in particular, the human-capital approach to estimate the prevalence-based economic costs of illicit drug use in ontario in 1992. this methodology is consistent with international guidelines formulated at the 1994 international symposium on economic and social costs of substance abuse. the economic cost of illicit drug use is estimated at $489.29 million ( ... | 1998 | 9541086 |
| human isolates of salmonella typhimurium dt104 in ontario. | 1998 | 9553281 | |
| human research beyond the medical model: legal and ethical issues. | advances in medical health depend on non-medical, as well as medical research. when research involves human participants, it raises legal and ethical concerns that have come to be approached by reference to codes of research ethics. many of these are centered on physician-patient relationships and the pursuit of medical science. this article considers a number of issues that arise from research that follows non-medical models of research, and applications of rules of ethical medical research out ... | 1997 | 9573707 |
| management of common musculoskeletal problems: a survey of ontario primary care physicians. | in canada, primary care physicians manage most musculoskeletal problems. however, their training in this area is limited, and some aspects of management may be suboptimal. this study was conducted to examine primary care physicians' management of 3 common musculoskeletal problems, ascertain the determinants of management and compare management with that recommended by a current practice panel. | 1998 | 9580733 |
| absence of association between genetic variation of the beta 3-adrenergic receptor and metabolic phenotypes in oji-cree. | to assess the association between the common missense variant, y64r, in the gene encoding the beta 3-adrenergic receptor, adrb3, and intermediate phenotypes related to obesity and niddm in canadian oji-cree. | 1998 | 9589254 |
| the economic costs of alcohol abuse in ontario. | the abuse of alcohol causes health and social problems, such as sickness, death, injury, pain, suffering and crime. these harms impose an economic burden on society. resources are used or foregone as a consequence of alcohol abuse. this article provides an estimate of the economic cost of alcohol abuse in ontario in 1992. it uses the cost-of-illness method, in particular, the human-capital approach to estimate the prevalence-based economic costs of alcohol abuse. this methodology is consistent w ... | 1998 | 9602474 |
| empirical examination of the ability of children to consent to clinical research. | this study examined the quality of children's assent to a clinical trial. in subjects younger than 9 years of age, understanding of most aspects of the study was found to be poor to non-existent. understanding of procedures was poor in almost all subjects. in addition, voluntariness may have been compromised in many subjects by their belief that failure to complete the study would displease others. if the fact that a child's assent has been obtained is used to justify the exposure of that child ... | 1998 | 9650109 |
| caged amphibian tadpoles and in situ genotoxicity monitoring of aquatic environments with the alkaline single cell gel electrophoresis (comet) assay. | in previous studies we demonstrated that indigenous amphibian tadpoles are suitable organisms for monitoring small bodies of water (e.g., creeks, ponds, and drainage ditches) using the alkaline single cell gel electrophoresis (scg) or 'comet' assay. this approach involves detection, under alkaline conditions, of cell dna fragments which on electrophoresis migrate from the nuclear core, resulting in a 'comet with tail' formation. however, although often plentiful, tadpoles are not present in all ... | 1998 | 9651536 |
| physicians' attire as perceived by young children and their parents: the myth of the white coat syndrome. | to determine if young children have a preference regarding whether physicians do or do not wear a white coat. | 1998 | 9655662 |
| an association between the common hereditary hemochromatosis mutation and the factor v leiden allele in a population with thrombosis. | 1998 | 9694741 | |
| home care quality management. where are we now? where do we go from here? | this article is the first of a series of three focusing on key management processes in home care--quality management, financial and information management, and, service and human resource management. the articles examine the current state of practice in ontario and suggest a desirable future state. in this first article, home care is defined and a brief description is provided from a national and provincial perspective. quality is also defined and the drivers for quality in home care outlined. u ... | 1998 | 9726177 |
| north american liver fluke (metorchis conjunctus) in a canadian aboriginal population: a submerging human pathogen? | 1998 | 9735521 | |
| halicephalobus gingivalis (stefanski, 1954) from a fatal infection in a horse in ontario, canada with comments on the validity of h. deletrix and a review of the genus. | although the original description given by stefanski (1954) was satisfactory, anderson & bemrick (1965), in describing h. deletrix (= micronema deletrix), claimed stefanski's description was "inadequate" and the species a "species inquirenda". thus, infections in horses and humans have been assigned to h. deletrix. we believe the species reported in horses and humans is h. gingivalis and that h. deletrix is its synonym. h. gingivalis is separated herein from forms found free-living. the genital ... | 1998 | 9772725 |
| g protein beta3 subunit gene variant and blood pressure variation in canadian oji-cree. | the subunits of the heterotrimeric g proteins are attractive candidate gene products for both susceptibility to essential hypertension and interindividual variation in blood pressure. there is alternative splicing of exon 9 of the gene encoding the beta3 subunit of heterotrimeric g proteins (gnb3) associated with a c-->t change at nucleotide 825, which activates a cryptic splice site. the 825t allele results in a gene product that is 41 amino acids smaller than the wild-type gene product. g prot ... | 1998 | 9774364 |
| twenty-five years of surveillance for contaminants in human breast milk. | to monitor the exposure of canadian populations, health canada has carried out six major surveys of breast milk contaminants, beginning in 1967. in these national surveys, breast milk was collected from nursing mothers at various times in their nursing period, and the concentrations of chlorinated hydrocarbons were measured. there was a downward trend from 1967 to 1992, in the concentrations of organochlorine (oc) pesticides and polychorinated biphenyl hydrocarbons (pcbs). this regression was ob ... | 1998 | 9776790 |
| population genetic characteristics of the str loci d21s11 and fga in eight diverse human populations. | a highly polymorphic multiplex short tandem repeat (str) system composed of d21s11, fga, and the sex-typing system amelogenin (amg) has been used to investigate allele frequency distributions in two canadian caucasian samples (british columbia and alberta), three canadian aboriginal populations (coastal salishans from british columbia, ojibwa from northern ontario, and cree from saskatchewan), and three ethnic groups from singapore (chinese, malays, and asian indians). using the automated fluore ... | 1998 | 9780514 |
| psychological outcomes following maternal serum screening: a cohort study. | maternal serum screening is used to assist in the prenatal detection of congenital anomalies. its use is controversial, and one concern that has been expressed is its psychological effects on women. the authors examined whether this test leads to an increase in anxiety and depression among women who have a false-positive result as compared with those who have a true-negative result or do not undergo testing. | 1998 | 9780964 |
| the cost-effectiveness of routine pathology consultation in knee arthroscopy. | regulations in ontario, canada, as in most provinces and states in north america, require human tissues (with few exceptions) removed at surgery to be sent to a pathology laboratory for examination and report. we hypothesized that this practice is inconsistently followed and that routine pathological consultation is costly and rarely results in a change in treatment for patients undergoing knee arthroscopy. chiefs of pathology, orthopaedic surgeons, and orthopaedic operating room nurse managers ... | 1998 | 9788364 |
| prevalence of upper extremity symptoms and possible risk factors in workers handling paper currency. | the prevalence of upper extremity symptoms in the workforce is high, particularly in industries characterized by forceful, repetitive or awkward movements. a study was undertaken to assess the prevalence of upper extremity symptoms in bank workers in a paper currency processing operation and to examine the role of possible risk factors for these complaints. thirty-nine workers of a total workforce of 47 were assessed with a questionnaire and physical examination. the questionnaire collected info ... | 1998 | 9800421 |
| a single-primer pcr-based retroviral-related dna polymorphism shared by two distinct human populations. | almost 10% of the human genome consists of dna sequences that share homology with retroviruses. these sequences, which represent a stable component of the human genome (although some may retain the ability to transpose), remain poorly understood. we used degenerate primers specific to the two conserved regions (boxes 4 and 5) of the retroviral pol gene, common to all retroviruses, and pcr-amplified related sequences from individuals representing two distinct populations: caucasians and dogrib in ... | 1998 | 9809437 |
| variation in the au(at)-rich element within the 3'-untranslated region of ppp1r3 is associated with variation in plasma glucose in aboriginal canadians. | we are investigating associations between variations in candidate genes on chromosome 7q and diabetes-related phenotypes in canadian oji-cree. one of these genes encodes the skeletal muscle regulatory g subunit of the glycogen-associated form of protein phosphatase 1 (pppir3), which may play a key role in muscle glycogen metabolism. there is a common 5-bp insertion-deletion polymorphism in a messenger ribonucleic acid-stabilizing au(at)-rich element within the 3'-untranslated region (utr) of ppp ... | 1998 | 9814479 |
| safe drinking water: a public health challenge. | disinfection of drinking water through processes including filtration and chlorination was one of the major achievements of public health, beginning in the late 1800s and the early 1900s. chloroform and other chlorination disinfection by-products (cbps) in drinking water were first reported in 1974. chloroform and several other cbps are known to cause cancer in experimental animals, and there is growing epidemiologic evidence of a causal role for cbps in human cancer, particularly for bladder ca ... | 1998 | 9820833 |
| survey of canadian human blood plasma for ochratoxin a. | blood plasma samples collected from 144 healthy volunteers in 16 locations across canada in 1994 were analysed for ochratoxin a (ota). the method of analysis included cleanup by c18 solid phase extraction and immunoaffinity columns followed by liquid chromatography (lc) with fluorescence detection, which gave 86.5% (s.d. = 9.7) recovery (n = 31) of ota (added at 2 ng/ml) with a detection limit of 0.15 ng/ml. the arithmetic mean concentration found in the plasma samples, corrected for volume of a ... | 1998 | 9829040 |
| dental human resource distribution in ontario: a report for 1997. | 1997 | 9879253 | |
| canadian case questions funding. | 1999 | 9880270 | |
| time-series analysis of the relation between influenza virus and hospital admissions of the elderly in ontario, canada, for pneumonia, chronic lung disease, and congestive heart failure. | this study examined the relation between the presence of circulating influenza virus and all hospital admissions of people over age 65 years in ontario, canada, for pneumonia, congestive heart failure, and chronic lung disease in 1988-1993. autoregressive integrated moving average (arima) transfer function models were used to perform a time-series analysis. these models were compared with simple cross correlations by using pearson's product moment correlation. the results showed statistically si ... | 1999 | 9883797 |
| a new model of advance care planning: observations from people with hiv. | although theoretical concepts from ethics and law have been applied, there is no conceptual model of advance care planning rooted in the perspective of individuals engaged in it. | 1999 | 9892336 |
| genome-wide scanning for type 2 diabetes susceptibility in canadian oji-cree, using 190 microsatellite markers. | we undertook a genome-wide scan using 190 markers with an average separation of 20 cm in 49 canadian oji-cree sib pairs affected with type 2 diabetes. four of these markers, one each on chromosomes 6, 8, 16, and 22, showed both suggestive linkage and suggestive association with type 2 diabetes in the oji-cree. none of these markers corresponded to any chromosomal region or marker that has so far been linked with type 2 diabetes in other populations. thus, there might be several genetic loci that ... | 1999 | 9929969 |
| independent review adds to controversy at sick kids. | 1999 | 10065085 | |
| the hepatic nuclear factor-1alpha g319s variant is associated with early-onset type 2 diabetes in canadian oji-cree. | mutations in the gene encoding hepatic nuclear factor-1alpha (hnf-1alpha) have been found in patients with maturity-onset diabetes of the young. we identified a new variant in the hnf-1alpha gene, namely g319s, in ontario oji-cree with type 2 diabetes. g319s is within the proline ii-rich domain of the trans-activation site of hnf-1alpha and alters a glycine residue that is conserved throughout evolution. s319 was absent from 990 alleles taken from subjects representing six other ethnic groups, s ... | 1999 | 10084598 |
| relation of lake ontario fish consumption, lifetime lactation, and parity to breast milk polychlorobiphenyl and pesticide concentrations. | lactating female members and spouses of male members of the new york state angler cohort who agreed to provide breast milk samples were the subjects of this study. questionnaires were provided to participants focusing on lake ontario fish consumption, reproductive history, and lactation history. milk samples were analyzed for 77 polychlorinated biphenyls (pcb) congeners, 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (dde), a metabolite of dichlorodiphenyltrichloroethane (ddt), hexachlorobenzene ... | 1999 | 10092430 |
| assessing environmental exposure to pcbs among mohawks at akwesasne through the use of geostatistical methods. | the mohawk nation at akwesasne is a native american community located along the st. lawrence river in new york state, ontario, and quebec. one component of a multiphase human health study was to assess the impact of different pathways of human exposure resulting from the off-site migration of polychlorinated biphenyl (pcb) contamination in this area. this paper illustrates how mapped residential information and environmental sampling data can be united to assist in exposure assessment for epidem ... | 1999 | 10092433 |
| the economic consequences of smoking in ontario. | smoking causes health and social problems such as sickness, death, fire, injury, pain and suffering. this paper provides an estimate of the economic burden imposed by the adverse health and social consequences of smoking in ontario in 1992. the cost-of-illness method, in particular, the human-capital approach is used to estimate the prevalence-based economic costs of smoking. the direct and indirect components of smoking-related costs are estimated and the total cost in ontario is us$2.91 billio ... | 1999 | 10094843 |
| an assessment of the environmental fate and exposure of benzene and the chlorobenzenes in canada. | systematic modelling of the fate of benzene and the chlorobenzenes is presented which follows a four-stage process of chemical classification, quantifying discharge rates and environmental concentrations, evaluative assessment of fate and regional mass balance modelling has been carried out for the southern ontario region. the eqc model was applied to determine the principal transport and transformation processes experienced by this group of chemicals, which vary considerably in volatility and h ... | 1999 | 10101848 |
| assessing the continuing education needs of long-term care administrators in ontario: results of a survey. | this article reports the results of a 1989 survey of the professional characteristics and educational needs of 429 managers and supervisors in long-term care institutions and community-based service agencies in greater metropolitan toronto. the data identify important gaps in the professional training of these administrators: while two-thirds report attainment of postsecondary education credentials, the remaining third, including a quarter of senior managers, have no formal college or university ... | 1991 | 10117524 |
| health science research ethics: a critique. | 1993 | 10125790 | |
| french-language health care services in ontario. | the french language services act, 1986 has had an impact on the provision of health care services in ontario. the ontario ministry of health's implementation of french-language services is examined in light of three criteria: permanency, quality and accessibility of services. issues are raised around the measurement and creation of demand for services; the health human resources shortage; health care priorities; what constitutes a high quality service; and the influence of the political and econ ... | 1994 | 10134903 |
| program management and health care informatics: defining relationships. | the program management (pm) structure is a relatively well-known organizational model for hospitals. a variation of the matrix structure, it allows for an interdisciplinary team of health care providers to facilitate patient care delivery. however, providing such focused care results in a complex, highly information-dependent operational environment. to meet the information needs of such an environment, careful planning in selecting and implementing technology is required. along with supporting ... | 1994 | 10140165 |
| an evaluation of a self-help clearinghouse: awareness, knowledge, and utilization. | this paper reports on an evaluation of the self-help clearinghouse of metropolitan toronto. the purpose of the clearinghouse is to facilitate the growth and development of self-help/mutual aid groups, and to inform and educate both the metropolitan toronto professional helping community and the larger community of the nature and availability of self-help. this study included: (a) a pre- and post-test assessment of awareness, knowledge, and utilization of the clearinghouse's services and (b) a d ... | 1993 | 10146510 |
| jean-claude martin: a man of vision. | 1990 | 10160589 | |
| physician impact analysis predictions in ontario hospitals: does the emperor have clothes? | physician impact analysis (pia) is a human resource planning tool used to predict the impact on hospital resources of adding a new or replacement physician to a hospital's medical staff. this article describes the findings of a study which examined the extent to which pias are used in ontario acute care hospitals and the accuracy of pia predictions. the results suggest that although pia appears to be widely used, there is no evidence that it meets the intended policy objective of accurately pred ... | 1996 | 10162423 |
| physician, heal thyself. | 1997 | 10175714 | |
| evaluation of a cold/flu self-care public education campaign. | the purpose of the study was to evaluate an ontario ministry of health (moh) cold/flu self-care public education campaign to reduce unnecessary patient visits to doctors. the moh campaign consisted of an information booklet delivered to every household in an ontario city, newspaper ads and radio spots. the program ran during january-march 1994. the evaluation consisted of: (1) 2x2 telephone survey in london (experimental area) and windsor (comparison area), before and during the campaign; and (2 ... | 1998 | 10178337 |
| elder abuse and one community's response. | elder abuse has come to be recognized as any act of both commission or omission that causes harm or loss to elderly people. this can include active or passive neglect, violence, sexual or emotional abuse, various kinds of theft, and deprivation of the person's human rights. elder abuse has many causes. the hastings and prince edward council on aging developed an elder abuse community response protocol to help address this problem. | 1998 | 10185311 |
| learning to support your work force in changing times. | this article looks at how one health care organization, the royal ottawa health care group, has taken a proactive approach to the human resource challenges associated with ongoing changes and transitions in the work place. the overriding objective has been to retain a stable, highly skilled and motivated work force, which is essential to providing quality care. | 1998 | 10187661 |
| design for the human factor. | 1982 | 10254514 | |
| community occupational therapists and volunteers: a survey of utilization and satisfaction. | current estimates lead us to believe that approximately 16% of the population works in some capacity on a volunteer basis. in spite of the size of this valuable human resource, occupational therapists often remark that they are unable to find suitable volunteers to assist with patient-related activities. the present study is an attempt to explore this topic, looking specifically at how community occupational therapists use volunteers, and how satisfied they are with the services provided. a desc ... | 1985 | 10271291 |
| human-centred design is a future facility prototype. | 1986 | 10280231 | |
| social inequality and healthy public policy. | for decades, health education programmes have been based on the assumption that individual behaviours (for example smoking, drug use, eating patterns) are the major risk-factors in contemporary illness. this assumption often led to interventions that subtly "blamed the victim" for his or her ill-health. in recent years the broader social conceptualization of health and illness has directed many health educators' attention towards socio-economic and environmental factors which condition and const ... | 1986 | 10286866 |
| mutual aid in remote areas: addressing the obstacles. | mutual aid is a powerful tool for individual and group change and an excellent means of promoting mental and physical health. this article examines the main factors that may hinder the development of self-help groups (shgs) in rural and remote areas, specifically the sudbury-manitoulin region of northern ontario. it considers several issues common to rural areas, such as population distribution, geographic isolation, lack and inaccessibility of human and material resources, and local factors suc ... | 1989 | 10294596 |
| consent and the human tissue gift acts: a rationale for change. | 1980 | 10309551 | |
| representing handicapped persons' claims under the ontario human rights code and the canadian charter of rights and freedoms. | 1983 | 10317404 | |
| report of survey of courses in medical terminology, human biology, health and disease presently required or available in programs in health or hospital administration. | 1978 | 10318396 | |
| determining ontario's supply and requirements for ophthalmologists in 2000 and 2005: 1. methods. | we performed a study to determine the supply of and requirements for ophthalmologists in ontario in 2000 and 2005. in this paper we describe our methods. | 1999 | 10321317 |
| morbidity and mortality related to human immunodeficiency virus in canadian men and women, 1987-94. | to assess the impact of hiv/aids on hospitalization and mortality patterns in canada. | 1999 | 10349221 |
| temporal and geographical distributions of reported cases of escherichia coli o157:h7 infection in ontario. | the distribution of 3001 cases of verocytotoxigenic escherichia coli (vtec) reported in the province of ontario, canada, were examined to describe the magnitude of this condition geographically and to evaluate the spatial relationship between livestock density and human vtec incidence using a geographical information system. incidence of vtec cases had a marked seasonal pattern with peaks in july. areas with a relatively high incidence of vtec cases were situated predominantly in areas of mixed ... | 1999 | 10355782 |
| the urology work force in ontario for the 21st century: feast or famine? | to address the issues of work-force planning and modelling in the 21st century for the specialty of urology in the province of ontario. | 1999 | 10372014 |
| cold/flu knowledge, attitudes and health care practices: results of a two-city telephone survey. | the purpose of this paper is to describe knowledge, attitudes and practices of cold and flu self-care and health care utilization, and to identify the predictors of health care utilization for the cold and flu among residents of london and windsor. using a random digit dialing survey method, 417 residents were interviewed between november-december, 1993 and february-march, 1994. this survey revealed good knowledge about colds and flu and understanding of appropriate physician visits. only seven ... | 1999 | 10401174 |
| the add1 g460w polymorphism is not associated with variation in blood pressure in canadian oji-cree. | since adducin modulates cellular sodium retention, its follows that add1, which encodes the alpha-subunit of adducin, is an attractive candidate gene for blood pressure variation. association studies examining the relationship between polymorphism at add1 codon 460 (g460w) and both hypertension and blood pressure, which were performed in a variety of human population samples derived from different genetic backgrounds, have given inconsistent results. we examined the association between the add1 ... | 1999 | 10429360 |
| the role of corticosteroids in the treatment of cerebral schistosomiasis caused by schistosoma mansoni: case report and discussion. | a 26-year-old brazilian man was admitted to the toronto hospital with a headache and visual scintillation. his last travel to brazil was five years previously. a computed tomography (ct) scan of the head showed an occipital mass with surrounding vasogenic edema. occipital brain biopsy revealed schistosoma mansoni eggs. the patient was treated with two doses of praziquantel (20 mg/kg) and dexamethasone (10 mg). his symptoms and occipital mass resolved. cerebral schistosomiasis is, in part, caused ... | 1999 | 10432054 |
| molecular typing methods to investigate transmission of escherichia coli o157:h7 from cattle to humans. | the utility of phage typing, pulsed-field gel electrophoresis (pfge), and plasmid profile analysis was compared, to differentiate between canadian escherichia coli o157:h7 strains of human (n = 27) and cattle (n = 24) origin. the diversity indices for phage typing, plasmid analysis and pfge were 0.85, 0.69 and 0.93, respectively. pfge and phage typing were also applied to study the role of direct transmission of e. coli o157:h7 from cattle to humans on isolates collected from two separate farm o ... | 1999 | 10487637 |
| environmental tobacco smoke exposure patterns: a subanalysis of the canadian human time-activity pattern survey. | this subanalysis of the canadian human activity pattern survey examines environmental tobacco smoke (ets) exposure in non-smoking respondents relative to age, sex, socioeconomic status and prevalence of asthma. 2,381 respondents (response rate 64.5%) from toronto, vancouver, edmonton and saint john completed a 24-hour recall time-activity diary. for each activity and location, respondents were asked, "was there any smoking during the activity?" among non-smoking adults, youth, children and asthm ... | 1999 | 10489721 |
| toronto street youth and hiv/aids: prevalence, demographics, and risks. | the purposes of this study were: (a) to identify human immunodeficiency virus (hiv) prevalence in toronto street youth through paired blood and saliva specimens; (b) to identify the hiv risk and prevention behaviors of street involved youth; and (c) to identify demographic or other factors that may contribute to the risk of street youth becoming infected with hiv/acquired immunodeficiency syndrome (aids) in the future. | 1999 | 10551667 |
| my aching back. the effects of system status management & ambulance design on ems personnel. | 1999 | 10557811 | |
| laboratory medicine in ontario: its downsizing and the consequences on quality. | health care in ontario consumes 35% of provincial government annual revenues. fiscal constraint mandates restructuring of health services to maintain a fully, publicly-funded universally-accessible health system that is patient-focussed and health-outcome driven. acute-care hospital restructuring under the authority of the health services restructuring commission and primary health-care reform characterise present government initiatives. laboratory medicine services at about can $1 billion annua ... | 1999 | 10585512 |
| common colds. reported patterns of self-care and health care use. | to describe the self-reported prevalence and patterns of self-care and health care use for colds and flu. | 1999 | 10587772 |
| the private hepatocyte nuclear factor-1alpha g319s variant is associated with plasma lipoprotein variation in canadian oji-cree. | we previously showed an extremely strong association between type 2 diabetes and a private polymorphism, namely g319s, in the hepatocyte nuclear transcription factor (hnf)-1alpha. because hnf-1alpha is involved in the transcription of several apolipoprotein genes, we tested for an association between the private hnf1a g319s variant and plasma lipoproteins in a sample of 55 unrelated oji-cree subjects with type 2 diabetes and 175 unrelated oji-cree subjects without type 2 diabetes. in oji-cree su ... | 2000 | 10634821 |
| human resource issues: a comparison by region. | 1999 | 10635151 | |
| inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, brca1, and brca2 mutations. | susceptibility to pancreatic adenocarcinoma appears to be linked to germ-line mutations in genes causing various familial cancer syndromes. the objectives of this study were to estimate the proportion of unselected pancreatic cancer patients belonging to hereditary cancer syndrome families and to determine the frequency ofp16, brca1, brca2, hmsh2, and hmlh1 germ-line mutations in patients with a personal or family history of cancer. the study population consisted of 102 patients with histologica ... | 2000 | 10667595 |
| narratives of identity: re-presentation of self in people who are homeless. | the problem of homelessness is a pressing social and health concern ascribed to the interaction between personal, social, economic, and service system resources. the article is based on a qualitative study of the experiences of 29 homeless individuals. in-depth interviews were conducted with single adult shelter users. analysis revealed the self to be a process that was continually developing. participants tacitly locate their self-concepts in the past, present, and future. these time frames ref ... | 2000 | 10724750 |
| income differences in persons seeking outpatient treatment for mental disorders: a comparison of the united states with ontario and the netherlands. | variations in the relationships among income, use of mental health services, and sector of care are examined by comparing data from 3 countries that differ in the organization and financing of mental health services. | 2000 | 10768701 |
| nat2 polymorphism associated with plasma glucose concentration in canadian oji-cree. | the prevalence of type 2 diabetes in the oji-cree of northern ontario is among the highest of any population in the world. we previously demonstrated that markers d8s264 and d22s683 were both linked and associated with type 2 diabetes in the oji-cree. among the possible candidate genes for type 2 diabetes and related traits on chromosomes 8p and 22q were nat2 and cyp2d6, respectively. we thus explored the possible association of nat2 and cyp2d6 alleles and diabetes-related traits in a sample of ... | 2000 | 10803679 |
| measuring the impact of influenza on the hospital admission rates of the elderly in ontario: a five-year admission rate analysis, 1988-1993. | a retrospective study was conducted to compare age- and sex-specific rates of hospital admission of the elderly in ontario for five influenza seasons from 1988-1993 for pneumonia, congestive heart failure and chronic respiratory disease. | 2000 | 10832182 |
| peroxisome proliferator-activated receptor-gamma2 p12a and type 2 diabetes in canadian oji-cree. | among the oji-cree of northern ontario, we previously identified a novel variant in the hnf1a gene, namely g319s, that was strongly associated with type 2 diabetes. however, the majority of subjects with diabetes did not have the hnf1a s319 variant, suggesting that there might be other genetic determinants of diabetes susceptibility. in the course of sequencing candidate genes in diabetic subjects who were homozygous for hnf1a g319/g319, we found that some of them had the pparg a12 variant. afte ... | 2000 | 10843190 |
| leukemia after exposure to benzene: temporal trends and implications for standards. | benzene is a human leukemogen. risk assessment, and the setting of occupational and environmental standards, has assumed that risk is constant in time after a unit of exposure. leukemia risk is known to vary with time after exposure to ionizing radiation. | 2000 | 10861761 |
| planning for cardiac surgical services: advice from an ontario consensus panel. for the consensus panel on cardiac surgical services in ontario and the steering committee of the cardiac care network of ontario. | the cardiac care network of ontario (ccn) consensus panel on cardiac surgical services drew on the literature and its own expertise to recommend guidelines for expanding services. this report, which is not an official position paper of the canadian cardiovascular society, presents these recommendations. rates of surgery are linked to diagnostic capacity, requiring increases in interventional therapies to match increases in invasive diagnostic activity. for quality and efficiency, panel members r ... | 2000 | 10863168 |
| parental consumption of contaminated sport fish from lake ontario and predicted fecundability. | wildlife studies suggest that consumption of contaminated fish from the great lakes may expose humans to polychlorinated biphenyls and persistent chlorinated pesticides. to assess whether time to pregnancy or fecundability is affected, we conducted a telephone survey in 1993 with female members of the new york state angler cohort study who were considering pregnancy between 1991 and 1994 (n = 2,445). among the 1,234 (50%) women who became pregnant, 895 (73%) had a known time to pregnancy. upon e ... | 2000 | 10874544 |
| limbs found in water: investigation using anthropological analysis and the diatom test. | we report the investigation, using a multi-disciplinary approach, of five cases of dismembered limbs which were recovered from lake ontario, lake erie and the niagara river, and examined at the office of the chief coroner for ontario. in all cases, postmortem examination revealed that the limbs had been disarticulated in the postmortem period, by non-human taphonomic processes. in addition to routine gross examination, the femur and/or tibia were assessed using anthropological methods to give es ... | 2000 | 10882826 |
| an outbreak of human blastomycosis: the epidemiology of blastomycosis in the kenora catchment region of ontario, canada. | 2000 | 10893821 | |
| thrombolysis in the air. air-ambulance paramedics flying to remote communities treat patients before hospitalization. | first nations* communities in the north have a high prevalence of coronary artery disease and type 2 diabetes and face an increasing incidence of myocardial infarction (mi). many conditions delay timely administration of thrombolysis, including long times between when patients first experience symptoms and when they present to community nursing stations, delays in air transfers to treating hospitals, uncertainty about when planes are available, and poor flying conditions. | 2000 | 10907571 |
| gender, obesity, hepatic nuclear factor-1alpha g319s and the age-of-onset of type 2 diabetes in canadian oji-cree. | among the oji-cree of northern ontario, women have both a higher prevalence and an earlier onset of type 2 diabetes compared to men. we studied the relationship between hnf1a s319 and both the presence of and the age-of-onset of type 2 diabetes in women and men separately. we found that: 1) in women, there was a significant difference in the mean age-of-onset of type 2 diabetes according to hnf1a genotype; and 2) in men, there was no difference in the mean age-of-onset of type 2 diabetes accordi ... | 2000 | 10951547 |
| biographical sketch of kenneth g. mckenzie (1892-1964). | this article is an expanded version of the opening address dr. morley delivered at a university of toronto symposium, "seventy-five years of neurosurgery in canada," celebrating the 75th anniversary of the appointment of kenneth g. mckenzie, canada's first career neurosurgeon, to the university of toronto and the toronto general hospital in 1923. kenneth g. mckenzie (1892-1964) was the first surgeon in canada to limit his practice to neurosurgery. this article contains a brief biographical study ... | 2000 | 10969961 |
| optimizing technologies in nurse practitioner education. | a provincial educational programme was launched in 1995 for primary-care nurse practitioners. a consortium of ontario university schools of nursing joined forces to provide a single, standardized educational programme at all 10 sites in both official languages. this demanding, clinically focused educational initiative required better access, support and efficiencies than could be provided by print copies and videoconferences alone. the development of a password-protected website allowed equal ac ... | 2000 | 10975092 |
| the application of ontario human rights legislation to the practice of occupational medicine. | although human rights legislation has important implications for occupational physicians, these implications may be overlooked in the practice of occupational medicine in other countries where human rights legislation may be different. the potential for significant oversights becomes greater as organizations continue to centralize international business support functions, such as occupational health services, operating from a single site. human rights legislation has important implications with ... | 2000 | 10975134 |
| influenza immunizations in the elderly: a continuous quality improvement project. | as part of the continuous quality improvement program at the toronto hospital's department of family & community medicine (tth-dfcm), it was considered necessary to examine the structures, processes and outcomes of influenza immunization for the elderly. | 2000 | 10992747 |
| prevalence and predictors of human papillomavirus infection in women in ontario, canada. survey of hpv in ontario women (show) group. | human papillomavirus (hpv) is thought to be the primary cause of cervical intraepithelial neoplasia and cervical cancer. we determined the age-specific prevalence of hpv infection and its risk factors in ontario women. | 2000 | 11006760 |
| familial resemblance for physique: heritabilities for somatotype components. | to examine familial resemblance in the heath-carter anthropometric somatotype in a sample of 328 participants from 103 nuclear families in northern ontario (canada). | 2000 | 11023117 |
| knowledge about human papillomavirus among adolescents. | to assess knowledge of human papillomavirus (hpv) among high school-aged adolescents. | 2000 | 11042295 |
| predictors of owner response to companion animal death in 177 clients from 14 practices in ontario. | to identify predictors of grief and client desires and needs as they relate to pet death. | 2000 | 11061379 |