Publications

sero-epidemiology of transfusion-transmissible infectious diseases among blood donors in osogbo, south-west nigeria.	transfusion-transmissible infectious agents such as hepatitis b virus (hbv), human immunodeficiency virus (hiv), hepatitis c virus (hcv) and syphilis are among the greatest threats to blood safety for transfusion recipients and pose a serious public health problem. this cross-sectional study was undertaken with the aim of determining the seroprevalence of hiv, hcv, hepatitis b surface antigen (hbsag) and syphilis and correlates the findings with sex and age to ascertain the associations, if any, ...	2009	20011640
clinical presentation and imaging of general paresis due to neurosyphilis in patients negative for human immunodeficiency virus.	the clinical presentations and mri of six patients with general paresis due to neurosyphilis were reviewed. diagnosis was based on neurological and psychiatric symptoms, positive treponema pallidum hemagglutination in cerebrospinal fluid (csf) and sera, and serology that was negative for human immunodeficiency virus by enzyme-linked immunosorbent assay. most patients had lymphocytic, monocytic pleocytosis and high protein levels in their csf. one patient had periodic lateral epileptiform dischar ...	2010	20080408
sexually transmitted diseases and anorectum.	sexually transmitted diseases (std) are a major public health problem because their incidence is increasing worldwide despite prevention campaigns and because they raise the risk of hiv infection. anorectal localisations of std are common among men who have sex with men (msm) but can also be seen among heterosexuals (men or women). transmission of such infections is due to anal sex or to other sexual behaviours like "fisting". although some pathogens (like human papillomavirus-hpv) are common in ...	2009	20163035
risk factors and prevalence of tuberculosis, human immunodeficiency virus, syphilis, hepatitis b virus, and hepatitis c virus among prisoners in pakistan.	the objective of this study was to evaluate the burden of sexual- and injection drug use-related infections in male prisoners in karachi, pakistan.	2010	20189863
characterization and serologic analysis of the treponema pallidum proteome.	treponema pallidum subsp. pallidum is the causative agent of syphilis, a sexually transmitted disease characterized by widespread tissue dissemination and chronic infection. in this study, we analyzed the proteome of t. pallidum by the isoelectric focusing (ief) and nonequilibrating ph gel electrophoresis (nephge) forms of two-dimensional gel electrophoresis (2dge), coupled with matrix-assisted laser desorption ionization-time of flight (maldi-tof) analysis. we determined the identity of 148 t. ...	2010	20385758
production of proinflammatory cytokines in the human thp-1 monocyte cell line following induction by tp0751, a recombinant protein of treponema pallidum.	the tissue destruction characteristic of syphilis infection may be caused by inflammation due to treponema pallidum and the ensuing immune responses to the pathogen. t. pallidum membrane proteins are thought to be potent inducers of inflammation during the early stages of infection. however, the actual membrane proteins that induce inflammatory cytokine production are not known, nor are the molecular mechanisms responsible for triggering and sustaining the inflammatory cascades. in the present s ...	2010	20596832
case records of the massachusetts general hospital. case 26-2010. a 54-year-old man with loss of vision and a rash.		2010	20818848
[serological markers in immigrant and spanish pregnant women in granada].	female immigration from less developed countries into spain has grown in number over the years, and could contribute to changing the prevalence of routine serological markers in pregnant women.	2010	20961669
human papillomaviruses prevalence and genital co-infections in hiv-seropositive women in ouagadougou (burkina faso).	the vaginal swabs among hiv-positive women in africa often revealed opportunistic infections such as human papillomavirus (hpv) and mycoplasma that induce respectively cervix cancer and diseases such as vaginosis, abortions, infertility in through salpingitis. the purposes of this study were to: (1) seek for, the prevalence of pathogens such as hpv and mycoplasma; (2) characterize the strains of hpv and estimate their prevalence; (3) identify among these women, those who were co-infected by thes ...	2010	21313918
[neurosyphilis: unexpected reunion with an old acquaintance].	a 45-year-old man was admitted to a psychiatric hospital with confusion and disorientation; he was suspected of having korsakoff syndrome. he was known to have a history of alcohol abuse, complicated by epileptic fits, and to have had a recent ischaemic cerebrovascular attack. unexpectedly, screening for syphilis turned out to be positive. examination of the cerebrospinal fluid led to the diagnosis of neurosyphilis. most neurological and psychiatric symptoms disappeared after treatment with anti ...	2011	21319069
treponema infection associated with genital ulceration in wild baboons.	the authors describe genital alterations and detailed histologic findings in baboons naturally infected with treponema pallidum. the disease causes moderate to severe genital ulcerations in a population of olive baboons (papio hamadryas anubis) at lake manyara national park in tanzania. in a field survey in 2007, 63 individuals of all age classes, both sexes, and different grades of infection were chemically immobilized and sampled. histology and molecular biological tests were used to detect an ...	2011	21411621
laryngeal syphilis: a case report.	syphilis is a sexually transmitted disease caused by the spirochete treponema pallidum. the complexity of the disease gained it the moniker "the great imitator"; it was william osler who said, "he who knows syphilis, knows medicine." in 1866, patrick watson of edinburgh, scotland, reported a case of a 36-year-old man in whom syphilis destroyed the larynx.(1) the diagnosis was made postmortem. it was once believed that this was the first reported total laryngectomy, but the credit should actually ...	2011	21422316
risky sexual behavior among patients in turkey with bipolar disorder, schizophrenia, and heroin addiction.	aim. risky sexual behavior associated with such sexually transmitted infections (stis) as hepatitis b and c, herpes, treponema pallidum, and neisseria gonorrhoeae, is more frequent among psychiatric patients and parenteral drug abusers than the general population. the aim of this study was to investigate risky sexual behavior in psychiatric outpatients diagnosed with schizophrenia (sch), bipolar disorder, and heroin addiction (ha), and to compare them with those observed in healthy controls. me ...	2011	21492406
[meningovascular neurosyphilis as the cause of ischemic cerebrovascular disease in a young man].	authors report a case of a 35-year-old male with right-sided mild paresis, incontinence, dysexecutive syndrome, short-term memory loss and behavioral changes. bilateral cerebral infarcts in the region of the caudate nuclei and the adjacent white matter were proved by brain mri and multiple stenoses of the branches of willis-circle were confirmed by mr angiography. elevated protein level and pleocytosis were found in the cerebrospinal fluid with intrathecal igg synthesis. serum rapid plasma reagi ...	2011	21498167
malignant syphilis with ocular involvement in an hiv-infected patient.	malignant syphilis is now considered a rare disease, more commonly affecting individuals with poor health, malnutrition or hiv infection. we present a 34-year-old man with hiv infection who developed multiple atypical cutaneous ulcerations, leonine facies, a scleral nodule and keratitis with visual loss. the diagnosis of malignant syphilis was delayed due to the insidious presentation, but was confirmed via immunohistochemical (ihc) staining with anti-treponema antibodies of a skin biopsy. signi ...	2011	21571984
seroprevalence of human immunodeficiency virus, hepatitis b and c viruses and syphilis among blood donors in koudougou (burkina faso) in 2009.	background: the high prevalence of numerous transfusion-transmitted infectious diseases such as human immunodeficiency virus (hiv), hepatitis b virus (hbv), hepatitis c virus (hcv) and syphilis in sub-saharan africa affects the safety of blood for recipients. this study was undertaken with the aim of determining the seroprevalence of hiv, hcv, hbv, syphilis and socio-demographic risk factors associated with blood donation in a new regional blood transfusion centre in burkina faso. material and m ...	2011	21839011