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reproductive toxicity of trenbolone acetate in embryonically exposed japanese quail.this study was conducted to assess the effects of a one time embryonic exposure to trenbolone acetate on reproductive development and function in japanese quail (coturnix japonica). embryos were exposed to either 0.05, 0.5, 5, or 50microg trenbolone or a sesame oil vehicle control at embryonic day 4. onset of puberty, gonadal histopathology, sperm motility, cloacal gland size, and male copulatory behavior were assessed in adults. trenbolone delayed onset of puberty in males, inhibited cloacal gl ...200716989888
effects of androgen disruption by dde on the development and functioning of the immune system in japanese quail.we hypothesized that immunosuppression in birds that is caused by exposure to antiandrogenic chemicals occurs mainly through disruption of the development of the androgen-sensitive avian lymphoid organ, the bursa of fabricius. injections of 20.0 or 40.0 mug of p,p'-dde [ethylene, 1,1-dichloro-2,2-bis(p-chlorophenyl)], an antiandrogen, were administered at embryonic day 1. bursas from only chicks treated with dde were larger than, had fewer follicles, and exhibited vacuolization within follicles ...200616997800
gross morphological features of the lung and air sac in the japanese quail.this study was conducted to reveal the morphological characteristics of the lung and air sacs in coturnix coturnix japonica (japanese quails). ten quails were allocated into two groups. tracheas of 5 quails with neoprene latex and 5 quails with methylmetacrylate were injected to fill the trachea and air sacs. latex embalmed animals were stored in 10% formaldehyde solution for two months. animals given methylmetacrylate were maserated in 30% potassium hydroxide at 40 degrees c for two days. lungs ...200617019058
fish on avian lampbrush chromosomes produces higher resolution gene mapping.giant lampbrush chromosomes, which are characteristic of the diplotene stage of prophase i during avian oogenesis, represent a very promising system for precise physical gene mapping. we applied 35 chicken bac and 4 pac clones to both mitotic metaphase chromosomes and meiotic lampbrush chromosomes of chicken (gallus gallus domesticus) and japanese quail (coturnix coturnix japonica). fluorescence in situ hybridization (fish) mapping on lampbrush chromosomes allowed us to distinguish closely locat ...200617028954
lack of estrogenic or antiestrogenic actions of soy isoflavones in an avian model: the japanese quail.isoflavones are soy compounds that possess weak estrogenic and antiestrogenic activities. in addition, phytochemicals, including isoflavones, may play a role in regulating seasonal reproductive cycles. as soy is a common constituent in poultry diets, the effect of these compounds on the reproductive system of production birds may be of concern. the present study examined the putative effects of soy isoflavones supplemented into the diet at 1 and 5% using endpoints of growth and reproduction in t ...200617032818
immunosenescence and age-related susceptibility to influenza virus in japanese quail.we evaluated juvenile, pubescent, reproductive adult, and aged japanese quail (coturnix coturnix japonica) to determine if there were age-related differences in immune function with the hypothesis that aged birds would have weaker immune responses. immune responses were measured using phytohemagglutinin (pha) skin test, antibody response to foreign red blood cells and exposure to an h9n2 influenza virus. adult birds consistently had stronger immune responses than young and aged birds. aged quail ...200717045650
reproductive aging in japanese quail, coturnix japonica is associated with changes in central opioid receptors.quantitative in vitro autoradiography was used to measure specific mu and delta opioid receptor densities in regions of the japanese quail, coturnix japonica, brain that regulates reproductive endocrine and behavioral responses to determine the possible involvement of the opioid system in reproductive decline seen during aging. densities were measured in selected brain regions of young sexually active (yam), young photoregressed (ypm), old reproductively senescent (oim) male, young active (yf), ...200617045975
effects of carotenoids from lucerne, marigold and tomato on egg yolk pigmentation and carotenoid composition.1. the effects of various sources of natural carotenoids (px alfalfa concentrate, tomato powder and marigold extract) as feed additives in quail diets on egg yolk pigmentation and carotenoid composition were investigated. 2. adult japanese quail were fed one of 5 different diets for 23 d: three diets each contained px alfalfa concentrate (px) or tomato powder (tp) or marigold extract (mg), one diet contained marigold extract and tomato powder (mg + tp) and a control diet (wheat/barley based) was ...200617050099
full genome sequence and some biological properties of reticuloendotheliosis virus strain apc-566 isolated from endangered attwater's prairie chickens.reticuloendotheliosis virus (rev) causes runting, high mortality, immunosuppression, and chronic neoplasia associated with t and/or b cell lymphomas in a variety of domestic and wild birds, including attwater's prairie chickens (apc) (tympanuchus cupido attwateri). the complete proviral sequence of a recent rev isolate from apc (rev apc-566) was determined. this virus was isolated from an apc maintained in captivity in a reproduction program intended to avoid its extinction. rev apc-566 was dete ...200717098316
on the positions of centromeres in chicken lampbrush chromosomes.using immunostaining with antibodies against cohesin subunits, we show here that cohesin-enriched structures analogous to the so-called centromere protein bodies (pb) are the characteristic of galliform lampbrush chromosomes. their centromeric location was verified by fish with certain dna probes. pb-like structures were used as markers for centromere localization in chicken lampbrush chromosomes. the gap predicted to be centromeric in current chicken chromosome 3 sequence assembly was found to ...200617115332
sexual fetishism in a quail (coturnix japonica) model system: test of reproductive success.in the present study, the authors explored the reproductive consequences of fetishistic behavior in a previously developed animal model of sexual fetishism (f. köksal et al., 2004). male domesticated quail (coturnix japonica) received sexual conditioning trials in which a terrycloth object (the conditioned stimulus [cs]) was paired with the opportunity to copulate with a female quail (the unconditioned stimulus). approximately half of the male quail came to copulate with the cs object and were c ...200617115864
effects of enclosure size on sexual behavior of japanese quail (coturnix japonica).the authors determined whether results of experiments on copulatory and affiliative behavior of pairs of japanese quail (coturnix japonica) conducted in a closely confining apparatus would predict behavior in a large enclosure in which female quail could avoid contact with male quail. as found previously in studies of closely confined quail, in a large enclosure containing numerous barriers, both unmated female quail and mated female quail laying unfertilized eggs were more likely to remain near ...200617115865
isolation of avian influenza virus a subtype h5n1 from internal contents (albumen and allantoic fluid) of japanese quail (coturnix coturnix japonica) eggs and oviduct during a natural outbreak.avian influenza virus (aiv) was recovered from the internal contents of eggs, including mixture of albumen and allantoic fluid, and from the oviduct of naturally infected japanese quail (coturnix coturnix japonica) flocks in the southern part of thailand. the virus titers of 10(4.6)-10(6.2) eld(50)/ml were directly measured from the internal content of infected eggs. the virus was isolated by chorioallantoic sac inoculation of embryonating chicken eggs. infected allantoic fluid was identified as ...200617135508
effect of arsanilic acid on performance and residual of arsenic in tissue of japanese laying quail.three hundred seventy-five 63-d-old laying japanese quail were randomly distributed into 3 experimental groups (125 birds per group) and fed the following diets for 40 d, with 30 d on the experimental diets, followed by a 10-d withdrawal period: 1) control; 2) 50 mg of 4-arsanilic acid/kg of feed; and 3) 100 mg of 4-arsanilic acid/kg of feed. each treatment consisted of 5 replicates of 25 birds. during the first 30 d of the experiment, all eggs were recorded, collected, individually weighed dail ...200617135662
no sex difference in yolk steroid concentrations of avian eggs at laying.yolk steroids of maternal origin have been proposed to influence genetic sex determination in birds, based on sex differences in yolk steroid concentrations of peafowl eggs incubated for 10 days. more recent reports dispute this proposal, as yolk steroids in eggs incubated for 3 days do not show such sex differences. to date, research examining this phenomenon has only analysed incubated eggs, although sex in avian species is determined before incubation begins. this may be a serious methodologi ...200517148197
mutations in slc45a2 cause plumage color variation in chicken and japanese quail.s*s (silver), s*n (wild type/gold), and s*al (sex-linked imperfect albinism) form a series of alleles at the s (silver) locus on chicken (gallus gallus) chromosome z. similarly, sex-linked imperfect albinism (al*a) is the bottom recessive allele at the orthologous al locus in japanese quail (coturnix japonica). the solute carrier family 45, member 2, protein (slc45a2), previously denoted membrane-associated transporter protein (matp), has an important role in vesicle sorting in the melanocytes. ...200717151254
immunotoxicity of trenbolone acetate in japanese quail.trenbolone acetate is a synthetic androgen that is currently used as a growth promoter in many meat-exporting countries. despite industry laboratories classifying trenbolone as nonteratogenic, data showed that embryonic exposure to this androgenic chemical altered development of the immune system in japanese quail. trenbolone is lipophilic, persistent, and released into the environment in manure used as soil fertilizer. this is the first study to date to assess this chemical's immunotoxic effect ...200717162502
correlated response in yolk testosterone levels following divergent genetic selection for social behaviour in japanese quail.maternal effects are a powerful tool that parents can use to modify the phenotype of their offspring. in birds, the amount of androgens that females deposit in their eggs has been shown to influence early development and adult behavioural phenotypes. differences in such behavioural strategies have been used as the target of artificial selection programmes with a view to improve animal welfare. in this study, we tested whether artificial selection for divergent social behaviour in japanese quail ...200717171709
sex differences in projections from preoptic area aromatase cells to the periaqueductal gray in japanese quail.in many vertebrate species the medial preoptic area projects to a premotor nucleus, the periaqueductal central gray (pag). this connection plays an important role in the control of reproductive behavior. in male japanese quail (coturnix japonica) specifically, the medial preoptic nucleus (pom), where various types of sensory inputs converge, is a critical site for the activational action of testosterone on male sexual behavior. to activate male copulatory behavior, testosterone must be aromatize ...200717177261
sensitivity of expression of perivitelline membrane glycoprotein zp1 mrna in the liver of japanese quail (coturnix japonica) to estrogenic compounds.avian perivitelline membrane protein, zp1, is synthesized and secreted by the liver with the stimulation of estrogens. in the present study, we measured the expression of zp1 gene in the liver of immature male quail treated with various estrogenic compounds and in the liver of male quail embryos that were developed in the fertilized eggs laid by mother quail injected with various estrogenic compounds during vitellogenesis. total rna extracted from the liver was reverse-transcribed and cdna was s ...200717188579
vertebrate and invertebrate carotenoid-binding proteins.in invertebrates and vertebrates, carotenoids are ubiquitous colorants, antioxidants, and provitamin a compounds that must be absorbed from dietary sources and transported to target tissues where they are taken up and stabilized to perform their physiological functions. these processes occur in a specific and regulated manner mediated by high-affinity carotenoid-binding proteins. in this mini-review, we examine the published literature on carotenoid-binding proteins in vertebrate and invertebrat ...200717188641
differential effects of 4 types of environmental enrichment on aggressive pecking, feather pecking, feather loss, food wastage and productivity in japanese quail.1. we examined the effects of 4 types of environmental enrichment (foraging opportunities, structural complexity, sensory stimulation/novelty, and social companionship) on aggressive and feather pecking, feather condition, food wastage, body weight, feed conversion, and egg production in adult japanese quail. sex differences were examined where possible. 2. glm analysis was used to evaluate the effects of enrichment and housing, while test-retest reliability and the stability of measures over 18 ...200617190672
[studies of the eating behavior of japanese quail chicks in the early postnatal period].time of the eating reaction (response to video signals) and eating behavior shortly after hatching were studied in japanese quail chicks whose embryonic development took place under normal or changed gravity. chicks partially incubated in a changed gravity showed a much slower eating reaction when compared with the chicks the prenatal development of which occurred under the normal gravity. in the chicks incubated at 1 g and placed in individual cages immediately after dominating afferentation fo ...200617193978
effects of 3-methyl-4-nitrophenol in diesel exhaust particles on the regulation of reproductive function in immature female japanese quail (coturnix japonica).in a previous study, we found that 3-methyl-4-nitrophenol (pnmc), a component of diesel exhaust particles and also a degradation product of the insecticide fenitrothion, exhibits reproductive toxicity in the adult male japanese quail. the present study investigated the toxicity of pnmc in the female japanese quail and its ability to influence reproduction in immature females. the quail (21-day-old) were injected intramuscularly (im) with pnmc at doses 0.1, 1 or 10 mg/kg body weight daily for 3 d ...200717202750
changes in the activity of acid glycosidases during posthatch development and regression after light reduction of japanese quail testes and epididymides.in this study specific activities of four acid glycosidases: beta-n-acethylhexosaminidase (beta-hex), beta-galactosidase (beta-gal), alpha- and beta-mannosidase (alpha- and beta-man) were investigated in japanese quail testes and epididymides during posthatch development and regression after light reduction. the specific activity of testicular beta-hex and beta-gal increased steadily during posthatch development and assumed maximum values for testes weighing 200-400 mg, when numerous spermatocyt ...200717215159
effects of cyanobacterial biomass on the japanese quail.mortality of wild aquatic birds has recently been attributed to cyanobacterial toxins. despite this, no experimental studies on the effects of defined doses of microcystins administered orally to birds exist. in this experiment, four groups of male japanese quails daily ingesting 10ml of microcystis biomass containing 0.045, 0.459, 4.605 or 46.044mug of microcystins, respectively, for 10 and 30 days, showed no mortality. histopathological hepatic changes in birds after the biomass exposure inclu ...200717217976
in vitro degradation of hexanitrohexaazaisowurtzitane (cl-20) by cytosolic enzymes of japanese quail and the rabbit.hexanitrohexaazaisowurtzitane (cl-20) is a polycyclic nitramine explosive and propellant, currently being considered as a potential replacement for existing cyclic nitramine explosives. earlier studies have provided evidence suggestive of adverse liver effects in adult coturnix spp. exposed to cl-20, yet analysis of tissue samples (plasma, liver, brain, heart, or spleen) indicated that cl-20 was not detectable in these treated animals. the present study was conducted to identify and purify the e ...200617220092
morphometrical studies of reproductive system of birds after treatment with dopamine receptor blockers and melatonin.male japanese quails were treated with melatonin alone or melatonin combined with d1 and d2 dopamine receptor blockers. following the treatment, hypothalamus, pituitary glands and testes were analyzed morphometrically. the results suggest the existence of an interaction between melatonin and dopaminergic system in the brain in the regulation of reproductive processes in immature birds. the character of this interaction alters according to the time of the treatment (morning, afternoon, evening, n ...200617220946
carbohydrate characterization of quail primordial germ cells during migration and gonadal differentiation.a selection of lectins were used to study changes in the distribution of sugar residues in primordial germ cells (pgcs) during gonadal colonization and differentiation. although the cytochemical characteristics of pgcs have been described in the chick, little is known about such characteristics in other avian species of interest to experimental biology. therefore, we studied embryos of japanese quail (coturnix coturnix japonica) by light and laser confocal scanning microscopy, using the qh1 anti ...200717229287
development and performances of a japanese quail line homozygous for the diabetes insipidus (di) mutation.a strain of japanese quail with the polyuria disorder (excessive urination) was developed from founders that regurgitated water spontaneously. a back-cross with a nonpolyuric quail line showed that the polyuric strain was fixed for an autosomal recessive mutation that also induced polydipsia (excessive drinking). plasma levels and brain mrna contents for avian arg vasotocin were little affected by the mutation, but plasma avian arg vasotocin was 13-fold higher and brain mrna contents were signif ...200717234837
induction of sperm acrosome reaction by perivitelline membrane glycoprotein zp1 in japanese quail (coturnix japonica).the extracellular matrix surrounding avian oocytes, called the perivitelline membrane (pl), consists of at least two major glycoproteins, zp3 and zp1. our previous study using japanese quail had demonstrated that the pl obtained from the preovulatory follicles was incubated in vitro with spermatozoa, and perforations were observed. this result indicated that the pl might contain a constituent that possesses activity to initiate the acrosome reaction (ar) in quail. in order to elaborate upon our ...200717244731
inbreeding depression in japanese quail. 196617248318
divergent selection under two nutritional environments for packed erythrocyte volume in japanese quail.two-way selection for two-week packed erythrocyte volume (pcv) was practiced for four generations under two nutritional environments in the japanese quail (coturnix coturnix japonica). one environment was an iron, copper-"adequate" diet and the other was iron, copper-deficient "stress" diet. response to selection was greater in both directions under the adequate environment than under the stress environment. after four generations of selection there were 29% and 18% differences between the high ...197317248623
polymerase chain reaction-restriction fragment length polymorphism of mitochondrial 12s rrna gene: a simple method for identification of poultry meat species.chicken (gallus gallus), duck (anas platyrhynchos), turkey (meleagris gallopavo), guinea fowl (numida meleagris) and quail (coturnix japonica) are the common poultry species consumed as meat throughout the world. in this work, a molecular technique has been developed for identification and differentiation of meat originating from these species. this tool helps in detection of misrepresentation of different poultry meats. the technique involves the extraction of dna from the given sample, polymer ...200717253115
laterality in syrinx muscle morphology of the japanese quail (coturnix japonica).in the japanese quail, normally only males crow, but treatment of adult females with testosterone (t) facilitates the behavior. the sternotrachealis muscles are thought to adjust the length of the trachea during inspiration and/or expiration and control rigidity of the cartilages of the vocal organ (syrinx) during phonation. these muscles are heavier in males than females, and t increases their mass in females [balthazart j, schumacher m, otttinger ma. sexual differences in the japanese quail: b ...200717258241
an age-specific 35-kda phosphoprotein binds to a repressor element in the ovalbumin gene promoter in the avian species japanese quail.the ovalbumin (ov) gene is expressed in the tubular gland cells of the avian oviduct in a specific manner under the control of developmental, tissue-specific, and hormonal cues. the expression is controlled by an array of positive and negative cis-acting elements present up to 1 kb upstream of its transcription start site. our findings presented in this communication indicate that a well-characterized repressor element may be involved in active repression of the gene during aging. at least two p ...200717263596
effect of glucagon-like peptide-1 and -2 on regulation of food intake, body temperature and locomotor activity in the japanese quail.to investigate the physiological roles of glucagon-like peptide-1 (glp-1) and glucagon-like peptide-2 (glp-2) in avian species, we elucidated the effect of intraperitoneal (i.p.) and intracerebroventricular (i.c.v.) administration of glp-1 and glp-2 on food intake, body temperature and gross locomotor activity in adult japanese quail. both i.p. and i.c.v. administration of glp-1 suppressed food intake at 2, 4 and 12h after administration. moreover, both i.p. and i.c.v. administration of glp-1 si ...200717267112
neuroanatomical specificity of sex differences in expression of aromatase mrna in the quail brain.in birds and mammals, aromatase activity in the preoptic-hypothalamic region (hpoa) is usually higher in males than in females. it is, however, not known whether the enzymatic sex difference reflects the differential activation of aromatase transcription or some other control mechanism. although sex differences in aromatase activity are clearly documented in the hpoa of japanese quail (coturnix japonica), only minimal or even no differences at all were observed in the number of aromatase-immunor ...200717270396
effects of early embryonic exposure to genistein on male copulatory behavior and vasotocin system of japanese quail.genistein is a phytoestrogen, particularly abundant in soybeans that can bind estrogen receptors and sex hormone binding proteins, exerting both estrogenic and antiestrogenic activity. in this study we used the japanese quail embryo as a test end-point to investigate the effects of early embryonic exposure to genistein on male copulatory behavior and on vasotocin parvocellular system. both differentiate by the organizational effects of estradiol during development and may therefore represent an ...200717274996
a light and electron microscopic study of the limb long bones perichondral ossification in the quail embryo (coturnix coturnix japonica).the perichondral ossification of the limb long bones in the quail embryo is investigated, in this study, by means of light and electron microscopy. longitudinal sections of the humerus, radius, ulna, femur, tibia and fibula stained with haematoxylin-eosin were examined by the light microscope. ultrathin cross sections were selected for the electron microscope as well. light microscopic analysis showed that the ossification began at the same time in the long bones of the wing and leg. at the embr ...200717312922
endothelin receptor b2 (ednrb2) is associated with the panda plumage colour mutation in japanese quail.the panda mutant in japanese quail (coturnix japonica) displays spots of wild-type plumage on a white background and is controlled by an autosomal recessive allele (s). the dotted white is controlled by a third allele (s(dw)) of the s locus with s(dw)/s(dw) quail having less pigmentation than s/s quail. we mapped the s locus to the japanese quail chromosome 4 (cja04) in a previous study. the orthologous region of the chicken (gallus gallus) genome includes endothelin receptor b2 (ednrb2), an avi ...200717313575
cocaine sensitization in male quail: temporal, conditioning, and dose-dependent characteristics.chronic cocaine administration typically results in increased locomotor activity, known as behavioral sensitization. investigating the time course of locomotor activity across trials may provide a more detailed analysis of the temporal changes that might occur within sensitization. prior research with rodents shows that the peak of locomotor activity shifts from acute to chronic drug administration. the purpose of the current experiment was to investigate acute versus chronic cocaine effects on ...200717316715
xenogenic oogenesis of chicken (gallus domesticus) female primordial germ cells in germline chimeric quail (coturnix japonica) ovary.in present study, chicken primordial germ cells (pgcs) were transferred into quail embryos to investigate the development of these germ cells in quail ovary. briefly, 2 microl of chicken embryonic blood (stage 14) or about 100 purified circulating pgcs were transferred into quail embryo. contribution of chicken pgcs were detected in gonads of chimeric quail embryos (stage 28) by immunocytochemical staining of cell surface antigen ssea-1, and by in situ hybridization (ish) with female chicken spe ...200717337136
melatonin and its synthesizing enzymes (arylalkylamine n-acetyltransferase-like and hydroxyindole-o-methyltransferase) in avian eggs and early embryos.the presence of melatonin and the enzymes (transcripts and activities) involved in its synthesis, i.e. arylalkylamine n-acetyltransferase (aa-nat) and hydroxyindole-o-methyltransferase (hiomt), was investigated in the eggs and early embryos of japanese quail at hamburger-hamilton stages 1-10. melatonin was present in the egg yolk (approximately 70 pg/g) and albumen (approximately 20 pg/g). the average content of melatonin was approximately 416 pg/egg. aa-nat and hiomt transcripts were present in ...200717349030
nitric oxide modulates gonadal and adrenal function in japanese quail coturnix coturnix japonica.nitric oxide (no) a gaseous neurotransmitter is reported to play an important role in controlling the release of luteinizing hormone releasing hormone (lhrh) in mammalian system. but its role has not been investigated in birds, where photoperiod plays an important role in regulating gonadal development. to investigate the effect of no on gonadal and adrenal function of japanese quail, in the first experiment, 3-weeks-old sexually immature quail received no donor sodium nitroprusside (snp, 5mg/10 ...200717353014
effects of supplemental vitamin e in diet of japanese quail on male reproduction, fertility and hatchability.1. two experiments were conducted to examine the effect of feeding higher supplemental vitamin e (ve) concentrations on male reproductive variables, fertility and hatchability of quails. 2. in experiment 1, sixty 5-week-old male quails, reared in individual cages, were fed male breeder diets supplemented with 0, 75, 150, 225 or 300 iu alpha-tocopherol acetate/kg. at 10 weeks, observations on cloacal gland size, foam production, testes weight and blood samples for testosterone estimation were tak ...200717364548
the testicular capsule and peritubular tissue of birds: morphometry, histology, ultrastructure and immunohistochemistry.the testicular capsule was studied histologically, morphometrically, ultrastructurally and immunohistochemically in the japanese quail, domestic fowl, turkey and duck (all members of the galloanserae). the testicular capsule was, relative to mammals, thin, being 81.5 +/- 13.7 microm in the quail, 91.7 +/- 6.2 microm in the domestic fowl, 104.5 +/- 29.8 microm in the turkey and 91.8 +/- 18.9 microm in the duck. the orchido-epididymal border (hilus) of the capsule was much thicker than elsewhere i ...200717451470
pathogenicity and transmission of reticuloendotheliosis virus isolated from endangered prairie chickens.the pathogenicity and transmission of a field isolate of reticuloendotheliosis virus (rev) was studied using an experimental model in japanese quail. oncogenicity was also evaluated after inoculations in chickens and turkeys. the original rev (designated apc-566) was isolated from attwater's prairie chickens (tympanuchus cupido attwateri), an endangered wild avian species of the southern united states. the transmissibility of the rev isolate was studied in young naive japanese quail in contact w ...200717461264
the effects of experimental aflatoxicosis on the exocrine pancreas in quails (coturnix coturnix japonica).the present investigation was undertaken to assess the effects of aflatoxin (af) on the exocrine pancreas in quails by means of light and electron microscopy. a total of 30 quails were divided into three groups, each composed of ten animals. total af was incorporated into the diet of these groups, at doses of 0, 2.5, and 5.0 mg of af/kg feed, ppm, respectively. the quails were raised in cages with electrical heating and 24-h lighting for a period of 3 weeks. ad libitum access was provided to fee ...200717486318
adaptation of influenza a/mallard/potsdam/178-4/83 h2n2 virus in japanese quail leads to infection and transmission in chickens.to assess the potential of quail as an intermediate host of avian influenza, we tested the influenza a/mallard/ potsdam/178-4/83 (h2n2) virus to determine whether through adaptation a mallard strain can replicate and transmit in quail, as well as other terrestrial birds. after five serial passages of lung homogenate a virus arose that replicated and transmitted directly to contact cage mates. to test whether adaptation in quail led to interspecies transmission, white leghorn chickens were infect ...200717494563
pathobiology of h9n2 avian influenza virus in japanese quail (coturnix coturnix japonica).clinical signs, serologic response, viral contents of the trachea and intestine, and histopathological and ultrastructural changes of the tracheal epithelium of japanese quail experimentally infected with field isolate of h9n2 avian influenza were studied. vaccinated and unvaccinated quail were inoculated with 10(6.3) 50% embryo infectious dose/bird of a/ chicken/iran/sh-110/99 (h9n2) virus via nasal inoculation. clinical signs such as depression, ruffled feathers, diarrhea, and nasal and eye di ...200717494591
expression of cell-cycle-regulating genes in the development of atherosclerosis in japanese quail (coturnix japonica).the levels of mrna expression in regulatory genes that are involved in the pathological changes of aortic atherosclerotic and fibroblastic intimal thickening was investigated in japanese quail. the quail were divided into a control diet group and an atherogenic diet group. the quail were euthanized at 2, 4, 8, and 12 wk after consuming either a control diet or an atherogenic diet. thereafter, both histological and immunohistochemical studies and mrna expression analysis of the cell-cycle-regulat ...200717495088
behavioral and neuropharmacological evidence that serotonin crosses the blood-brain barrier in coturnix japonica (galliformes; aves).this study was carried out aiming to reach behavioral and neuropharmacological evidence of the permeability of the blood-brain barrier (bbb) to serotonin systemically administered in quails. serotonin injected by a parenteral route (250-1000 microg x kg(-1), sc) elicited a sequence of behavioral events concerned with a sleeping-like state. sleeping-like behaviors began with feather bristling, rapid oral movements, blinking and finally crouching and closure of the eyes. previous administration of ...200717505765
correlation of nitric oxide (no) activity and gonadal function in japanese quail, coturnix coturnix japonica following temporal phase relation of serotonergic and dopaminergic oscillations.nitric oxide (no), a highly reactive and short-lived radical, is considered to be an important trigger molecule for several physiological mechanisms including gonadotrophin releasing hormone (gnrh) secretion in mammals, although there is no such information in avian literature. on the other hand, specific temporal phase relation of circadian neural (serotonergic and dopaminergic) oscillations is reported to modulate reproductive activity in many avian species including japanese quail. the presen ...200817512145
gross morphological and histological features of larynx, trachea and syrinx in japanese quail.this study aimed at observing gross morphological and histological characteristics of the larynx, trachea and syrinx in coturnix coturnix japonicum (japanese quail). sixteen mature quails were divided into two groups. eight animals were stained with 0.1% methylene blue for 15 min, followed by 50% and 70% ethyl alcohol solution for gross morphological examination. for the observation of histological characteristics the larynx, trachea and syrinx were fixed in 10% formaldehyde and embedded in para ...200717535355
asymmetry of visually guided sexual behaviour in adult japanese quail (coturnix japonica).sexually active adult japanese quail (coturnix coturnix japonica) were trained to run across either a left- or a right-turning runway to obtain sexual access to a conspecific of the opposite sex. the birds tested with only their right eye in use showed significantly higher latencies to complete the runway task than the birds tested binocularly and those using the left eye. in all of the three experimental conditions, male birds were significantly faster than their female counterparts. generally, ...200717558814
differential c-fos expression in the brain of male japanese quail following exposure to stimuli that predict or do not predict the arrival of a female.we investigated the effects of presenting a sexual conditioned stimulus on the expression of c-fos in male japanese quail. eight brain sites were selected for analysis based on previous reports of c-fos expression in these areas correlated with sexual behaviour or learning. males received either paired or explicitly unpaired presentations of an arbitrary stimulus and visual access to a female. nine conditioning trials were conducted, one per day, for each subject. on the day following the ninth ...200717561846
the effect of soy isoflavones on egg quality and bone mineralisation during the late laying period of quail.1. soy isoflavones play a role in calcium and bone metabolism. poor egg quality, skeletal abnormalities and architectural deterioration of bone tissue are common problems under hot climate conditions and with increased age in poultry. 2. in this study, we investigated the effects of soy isoflavone supplementation on egg production, egg quality, bone mineral density (bmd), levels of osteocalcin (oc), vitamin d, calcium (ca), phosphorus (p) and alkaline phosphatase (alp) activity in quail (coturni ...200717578700
intensity and duration of corticosterone response to stressful situations in japanese quail divergently selected for tonic immobility.two genotypes of japanese quail have been divergently selected since the 1980s for long (lti) or short (sti) duration of tonic immobility [mills, a.d., faure, j.m., 1991. divergent selection for duration of tonic immobility and social reinstatement behavior in japanese quail (coturnix coturnix japonica) chicks. j. comp. psychol. 105(1), 25-38.], an unlearnt catatonic state characteristic of a behavioral fear response ([jones, r.b., 1986. the tonic immobility reaction of the domestic fowl: a revi ...200817586506
developmental stage affects eggshell-breaking strength in two ground-nesting birds: the partridge (alectoris rufa) and the quail (coturnix japonica).we examined the relationship between embryo development and egg hardness in two ground nesting bird species, the red-legged partridge (alectoris rufa; n = 165 eggs) and the quail (coturnix japonica; n = 148 eggs). for both species, we observed a strong effect of developmental stage on egg hardness. eggs near hatching were significantly weaker than unincubated eggs (partridge: 18 and 23 n, respectively, and the quail 7 and 10 n, respectively). we additionally explored the effect of incubation on ...200717600815
inbreeding in japanese quail estimated by pedigree and microsatellite analyses.accurately estimating inbreeding is important because inbreeding reduces fitness and production traits in populations. we analyzed information from pedigrees and from microsatellite markers to estimate inbreeding in a line of japanese quail derived from a randombred line (qo) and maintained for 17 generations by pedigreed matings of brothers to groups of sisters. pedigree data were used to calculate the inbreeding coefficient (f(it)), which is the level of inbreeding based on a reference ancesto ...200717602180
association of the fads2 gene with omega-6 and omega-3 pufa concentration in the egg yolk of japanese quail.this study focused on the association of polymorphisms of the fads2 gene with fatty acid profiles in egg yolk of eight japanese quail lines selected for high and low omega-6:omega-3 pufa ratio (h2 = 0.36-0.38). for the identification of polymorphisms within the fads2 gene 1350 bp of cdna sequence were obtained encoding 404 amino acids. five synonymous snps were found by comparative sequencing of animals of the high and low lines. these snps were genotyped by single base extension on 160 japanese ...200717612842
photoperiodic changes in hypothalamic insulin receptor gene expression are regulated by gonadal testosterone.in order to adapt to seasonal changes, animals exhibit robust changes in their reproductive status, body weight, and molt. however, the molecular mechanisms regulating such seasonal changes in physiology and behavior are not fully understood. here, we report the photoperiodic regulation of the insulin receptor (ir) gene in the infundibular nucleus (anatomically homologous to the mammalian arcuate nucleus) of the japanese quail. when the birds were transferred from short-day to long-day condition ...200717618942
tandem 41-bp repeats in chicken and japanese quail genomes: fish mapping and transcription analysis on lampbrush chromosomes.the chromosomal distribution of 41-bp repeats, known as cnm and po41 repeats in the chicken genome and bglii repeats in the japanese quail, was analyzed precisely using giant lampbrush chromosomes (lbc) from chicken, japanese quail, and turkey growing oocytes. the po41 repeat is conserved in all galliform species, whereas the other repeats are species specific. in chicken and quail, the centromere and subtelomere regions share homologous satellite sequences. rna polymerase ii transcribes the 41- ...200717619894
characterization of crf, avt, and acth cdna and pituitary-adrenal axis function in japanese quail divergently selected for tonic immobility.higher corticosterone (cort) responses to acute stress have previously been reported in quail selected for short (sti) duration of tonic immobility (ti) than for long ti (lti), although behavioral studies indicated that lti quail were more fearful. to investigate adrenal and pituitary function in these quail lines and their possible involvement in the differences in hypothalamic-pituitary-adrenal (hpa) axis reactivity, we measured cort responses to adrenocorticotropin (1-24 acth), corticotropin- ...200717626128
effects of the dominant lethal yellow mutation on reproduction, growth, feed consumption, body temperature, and body composition of the japanese quail.wild-type japanese quail were compared with full-sibs with a yellow plumage color determined by an autosomal dominant mutation (y), which is lethal when homozygous. these quail have wheat-straw yellow-colored feathers. early growth was slower in yellow quail that had 2.4% lower bw than wild-type quail (149.3 g vs. 153.0 g) at 28 d of age. the bw, however, was similar for yellow and wild-type males at 35 d, and it remained so throughout the last part of the growth of the quail monitored until the ...200717626808
effect of photoperiod and estrogen on expression of arginine vasotocin and its oxytocic-like receptor in the shell gland of the japanese quail.the avian neurohypophysial hormone arginine vasotocin (avt) is an important regulatory hormone involved in many physiological processes including fluid balance, blood pressure regulation, stress responses and reproductive events including oviposition. the mechanisms by which avt stimulates myometrial contraction during oviposition are not well established in birds. in the present study, immunohistochemistry and in situ hybridization were used to localize avt and the oxytocin-like vt3 receptor in ...200717627858
risk assessment of the organophosphate pesticides isazofos and pyraclofos using a 21-day dietary toxicity study in japanese quail.six-week-old male and female japanese quails (coturnix japonica) received two organophosphate pesticides, isazofos and pyraclofos, for a 21-day dietary toxicity test, based on the oecd workshop report. during the treatment period, body weight and food consumption of the quail decreased with exposure to either isazofos or pyraclofos. using the up-and-down procedure to determine the 50% mortality value, we found that the 21-day lc(50) of isazofos and pyraclofos were 40 and 87 mg/kg body weight, re ...200817629558
identification and metabolic transformations of carotenoids in ocular tissues of the japanese quail coturnix japonica.as in humans and monkeys, lutein [(3r,3'r,6'r)-beta,epsilon-carotene-3,3'-diol] and zeaxanthin [a mixture of (3r,3'r)-beta,beta-carotene-3,3'diol and (3r,3's-meso)-beta,beta-carotene-3,3'-diol] are found in substantial amounts in the retina of the japanese quail coturnix japonica. this makes the quail retina an excellent nonprimate small animal model for studying the metabolic transformations of these important macular carotenoids that are thought to play an integral role in protection against l ...200717630780
expression of estrogen receptor-alpha and -beta mrna in the brain of japanese quail embryos.the present study was conducted to investigate the mrna expression of the two estrogen receptor (er) subtypes eralpha and erbeta in the brain of japanese quail embryos. we found expression of both eralpha and erbeta mrna in homogenate of whole head from 6-day-old embryos, and in brain homogenate from 9- and 12-day-old embryos using real-time pcr. in 9- and 12-day-old embryos the eralpha expression was higher in females than in males. we used in situ hybridization to examine the localization of t ...200717638389
energetic trade-offs between immunity and reproduction in male japanese quail (coturnix coturnix).we investigated a postulated trade-off between reproduction and immune function by comparing the energetic costs of an immune response with phytohemagglutinin challenge (or injection) in castrated (low testosterone [t]) and intact (high t) japanese quail (coturnix coturnix). intact birds had higher resting metabolic rate (rmr) and significantly lower immune response than castrates. rmr of intact birds did not change in response to an immune challenge, suggesting that maintenance of reproductive ...200717647272
a comparison of the protective action of added egg yolks from five avian species to the cryopreservation of bull sperm.cryopreservation of domestic animal sperm has been widely used for artificial insemination (ai), and egg yolk is one of the most commonly used cryoprotectants during the freezing-thawing process. the objectives of this study were to compare the effectiveness of egg yolk from five avian species (domestic chicken, domestic duck, domestic goose, japanese quail or domestic pigeon) and to optimize the concentration of egg yolk on the cryopreservation of bull sperm in terms of frozen-thawed sperm prog ...200817662543
neuroendocrine and immune characteristics of aging in avian species.avian species show a remarkable diversity in lifespan. the differing lifespan patterns are found across a number of birds, in spite of higher body temperature and apparent increased metabolic rate. these characteristics make study of age-related changes of great interest, especially for understanding the biology of aging associated with surprisingly long lifespan in some birds. our studies have focused on a short-lived avian model, the japanese quail in order to describe reproductive aging and t ...200717675878
effects of corticosterone treatment on growth, development, and the corticosterone response to handling in young japanese quail (coturnix coturnix japonica).corticosterone, a glucocorticoid secreted during stress responses, has a range of actions that help birds respond to stressors. although effects of corticosterone treatment have been described in several avian species, the impacts of defined increases in plasma corticosterone on early development and on corticosterone stress responses are little known. these issues were addressed by providing quail with different doses of corticosterone in drinking water from days 8 to 38 post-hatch. the cortico ...200717681843
aquaporin-2 water channel in developing quail kidney: possible role in programming adult fluid homeostasis.avian kidneys have loopless and looped nephrons; a countercurrent multiplier mechanism operates in the latter by nacl recycling. we identified an aquaporin-2 (aqp2) homolog in apical/subapical regions of cortical and medullary collecting duct (cd) cells in kidneys of japanese quail (q), coturnix japonica. we investigated whether undernutrition during the embryonic/maturation period retards kidney and aqp2 development in quail and programs impaired volume regulation in adults. protocols included ...200717699563
alkaline phosphatase reactivity in the vagina and uterovaginal junction sperm-storage tubules of turkeys in egg production: implications for sperm storage.1. currently there remains contradictory information on the localisation and possible role of alkaline phosphatase (ap) in the chicken and japanese quail oviducts. 2. using turkeys with a hard-shelled egg in their uteri, vaginal and uterovaginal junction mucosae were stretched and fixed as whole mounts prior to the histochemical localisation of ap activity. 3. scattered ap reactive cells were observed in the vaginal and uterovaginal junction surface epithelia and intense ap reactivity of the spe ...200717701505
ontogeny of the cloacal gland in male japanese quail classified in a t-maze.broiler chicks that traverse a t-maze quickly to reinstate contact with their companions (hp, high performers) are known to grow faster, are more social, and have a reduced plasma corticosterone response to acute stress than slower chicks (lp, low performers). high-performing quail from a line selected for reduced rather than exaggerated (high-stress) adrenocortical stress responsiveness also show enhanced female reproductive performance when compared with lp-high-stress quail. herein, time cour ...200717704392
3-methyl-4-nitrophenol metabolism by uridine diphosphate glucuronosyltransferase and sulfotransferase in liver microsomes of mice, rats, and japanese quail (coturnix japonica).3-methyl-4-nitrophenol (pnmc) is a component of diesel exhaust particles and one of the major breakdown products of the insecticide fenitrothion. this chemical has a high potential for reproductive toxicity in japanese quail (coturnix japonica) and rats. because pnmc inhaled by the body is metabolized by uridine diphosphate glucuronosyltransferase (ugt) and sulfotransferase, we investigated these enzyme activities in the hepatic microsomes and cytosols of quail (as a model of wild birds) and com ...200717705660
behavioural and endocrine fear responses in japanese quail upon presentation of a novel object in the home cage.most tests used to study fear in birds involve transferring them to a novel environment, which constitutes a bias in studies aiming at identifying the neural correlates of a specific fear-inducing situation. in order to investigate fear in birds with minimum interference by humans, behavioural and endocrine responses to the presentation of a novel object in the home cage were investigated in two lines of japanese quail divergently selected for long or short duration of tonic immobility, a behavi ...200817720332
modified saponification and hplc methods for analyzing carotenoids from the retina of quail: implications for its use as a nonprimate model species.to investigate carotenoid content in the retina of japanese quail (coturnix japonica), for comparison with carotenoids in human retina, and to assess the effects of different saponification procedures on the recovery of quail retinal carotenoids.200717724175
hydrated sodium calcium aluminosilicate for reduction of aflatoxin in quails (coturnix coturnix japonica).the purpose of the present study was to evaluate the toxic effects of aflatoxin (af) on growth performance and various processing parameters of quails and to determine the preventive efficacy of hydrated sodium calcium aluminosilicate (hscas). one hundred and eighty 1-d-old quails of both sexes were randomly divided into 4 experimental groups with 5 replicates and 45 birds following weighing. the experimental design consisted of four dietary treatments: 1) control with 0 mg af/kg of diet and 0% ...200717724933
learning effects on sperm competition and reproductive fitness.learning and other common psychological processes presumably evolved because they contribute to reproductive fitness, but reproductive outcomes are rarely measured in psychology experiments. we examined the effects of pavlovian conditioning on reproductive fitness in a sperm-competition situation. typically, two males mating with the same female in immediate succession sire similar numbers of offspring. in a study with domesticated quail (coturnix japonica), we increased paternity success by pre ...200717760768
photoperiodic control of the cloacal gland of the japanese quail.changes in photoperiod cause correlated changes in testes, cloacal glands, cloacal foam, and reproductive behavior of male japanese quail. the cloacal protrusion may serve as a convenient external index of androgen, permitting repeated measurement without operation on or killing of the animal.196717806265
eyes have a role in photoperiodic control of sexual activity of coturnix.in blinded japanese quail (coturnix coturnix japonica) encephalic photoreception of the stimulus from long photoperiods is sufficient to induce and maintain normal gonadal function in females (egg laying) and in males (enlargement of the cloacal gland). however, the termination of sexual activity by short days is dependent on these birds having experienced long days at the time of blinding.197217815368
sexual experience modulates neuronal activity in male japanese quail.after an initial increase, repeated exposure to a particular stimulus or familiarity with an event results in lower immediate early gene expression levels in relevant brain structures. we predicted that similar effects would occur in japanese quail after repeated sexual experience within brain areas involved in sexual behavior, namely, the medial preoptic nucleus (pom), the bed nucleus of stria terminalis (bst), and the nucleus taeniae of the amygdala (tna), an avian homolog of medial amygdala. ...200717826778
brain microvascular and intracranial artery resistance to atherosclerosis is associated with heme oxygenase and ferritin in japanese quail.oxidative stress and increased oxidation of low-density lipoprotein (oxldl) through free radical-mediated tissue injury may be important factors in the development of extracranial atherosclerotic lesions. however, the roles of oxidative stress and hypercholesterolemia in intracranial atherosclerosis is less established. the induction of heme oxygenase (ho) is a cellular response to oxidative stress, and inducible ho (ho-1) may protect against oxidized lipids such as those produced by oxidative s ...200817846865
vegf-related protein isolated from vipera palestinae venom, promotes angiogenesis.therapeutic angiogenesis is one of the major approaches in designing new therapies for cardiovascular diseases. vpvegf was purified from vipera palestinae venom using two steps of reverse-phase hplc. structurally, vpvegf belongs to the vegf-f1 family of snake venom proteins, and potently stimulated dhmvec proliferation in a vegfr-2 dependent manner. this growth factor appeared to be a chemoattractant for migration of these cells and stimulated their radial migration in a collagen gel. the stimul ...200717852405
effects of xenoestrogens on the differentiation of behaviorally-relevant neural circuits.it has become increasingly clear that environmental chemicals have the capability of impacting endocrine function. moreover, these endocrine disrupting chemicals (edcs) have long term consequences on adult reproductive function, especially if exposure occurs during embryonic development thereby affecting sexual differentiation. of the edcs, most of the research has been conducted on the effects of estrogen active compounds. although androgen active compounds are also present in the environment, ...200717868795
production of quail (coturnix japonica) germline chimeras derived from in vitro-cultured gonadal primordial germ cells.a previous report from our laboratory documented successful production of quail (coturnix japonica) germline chimeras by transfer of gonadal primordial germ cells (gpgcs). subsequently, this study was designed to evaluate whether gpgcs can be maintained in vitro for extended period, and furthermore, these cultured pgcs can induce germline transmission after transfer into recipient embryos. in experiment 1, gonadal cells from the two strains (wild-type plumage (wp) and black (d) quail) were cultu ...200817874456
estimation of chemical toxicity to wildlife species using interspecies correlation models.ecological risks to wildlife are typically assessed using toxicity data for relatively few species and with limited understanding of differences in species sensitivity to contaminants. empirical interspecies correlation models were derived from ld50 values for 49 wildlife species and 951 chemicals. the standard wildlife test species japanese quail (coturnix japonica) and mallard (anas platyrhynchos) were determined to be good surrogates for many species within the database. cross-validation of a ...200717874802
nocturnal plasma levels of melatonin in quails (coturnix japonica) injected with l-5-hydroxy-tryptophan.this study aimed to demonstrate the influence of the systemic administration of l-5-hydroxy-tryptophan (l-htp) on the plasma levels of melatonin during the dark period in quails. throughout daylight, the plasma levels of melatonin did not differ significantly, oscillating between 110.2 +/- 15.8 pg.ml(-1) and 157.4 +/- 34.8 pg.ml(-1), from 8 to 16 hours. l-htp (25 mg.kg(-1), through the intracelomic route) administered at 18 hours lessened significantly the nocturnal increase of the plasma levels ...200717876450
possible role of calcium on oocyte development after intracytoplasmic sperm injection in quail (coturnix japonica).although a rise in intracellular calcium concentration of vertebrate oocytes plays a pivotal role for the initiation of fertilization or oocyte activation, no study on this subject has been reported in birds. this study was conducted to study the role of intracellular calcium in relation to fertilization in avian oocytes. first, immediately after a quail oocyte was injected with a sperm, it was treated with strontium chloride as an inducer for intracellular calcium rise at doses of 0, 2.5, 5, 7. ...200717899613
changes in vasotocin immunoreactivity of paraventricular nuclei and adrenal function of japanese quail in relation to different phases of sexual development.in relevance to osmoregulatory and reproductive functions, activity of hypothalamic neurosecretory neurons may also vary seasonally. the current study was performed to determine annual changes in ir-avt neurons of hypothalamus and adrenal gland function. we examined changes in ir-avt neuron by immunohistochemical method and plasma testosterone was measured by enzyme immunoassay. the steroidogenic interrenal activity was studied by histological and biochemical methods. birds were sampled in febru ...200817900850
dietary tomato powder supplementation in the prevention of leiomyoma of the oviduct in the japanese quail.spontaneous leiomyomas of the oviduct are common tumors of the japanese quail (coturnix coturnix japonica), which makes it a good animal model for screening potential agents for testing in the prevention and treatment of human myoma uteri. we have previously reported a decreased incidence of leiomyomas in the oviduct of japanese quail with lycopene supplementation. although the major carotenoid in tomatoes is lycopene, tomatoes also contain other compounds, which may contribute to their health b ...200717927504
mechanism of chalaza formation in quail eggs.the present study was conducted to determine the mechanism of chalaza formation in eggs of the japanese quail coturnix japonica and to determine the production site of chalaza materials in the oviduct. electrophoretic profiles of the chalaza materials showed six bands of 480, 320, 210, 180, 96, and 58 kda following coomassie blue staining and one band of 600 kda after immunoblotting. an antiserum was produced against the 180-kda band. this antiserum and an antiserum generated against the 600-kda ...200717938966
polychlorinated biphenyl effects on avian hepatic enzyme induction and thyroid function.polychlorinated biphenyls (pcbs) decrease thyroid function in laboratory rodents by inducing activity of a liver enzyme, uridine diphosphate-glucuronosyltransferase (udp-gt), thereby increasing thyroxine (t4) clearance. this loss of t4 can lead to hypothyroidism. in this study, an assay was validated for measuring udp-gt activity toward t4 in japanese quail. udp-gt induction by aroclor 1254 was evaluated in quail, and responses of quail and mice were compared. in experiment 1, japanese quail and ...200817950733
divergent selection for shape of growth curve in japanese quail. 3. onset of sexual maturity and basic characteristics of early lay.1. the onset of lay, quality of eggs during early lay and gonadal development of both sexes were analysed in meat-type lines of japanese quail, hg and lg divergently selected for high and low relative weight gain between 11 and 28 d of age, respectively, and constant body weight (bw) at 49 d of age. 2. the lg line was sexually mature at an earlier age and lower bw than the hg line. this corresponded with the trend during embryonic and early postnatal development. 3. analysis of gonads also confi ...200717952726
primary structure and tissue distribution of gpr39 messenger ribonucleic acid in japanese quail, coturnix japonica.it has been found that gpr39 is an orphan receptor that belongs to the family of g protein-coupled receptors. in mammals, gpr39 has been shown to be involved in the regulation of gastrointestinal and metabolic function. in this study, we performed cdna cloning for gpr39 in japanese quail and characterized the tissue expression profiles of its mrna. the cdna encoded 462 amino acids, showing very high sequence homology to chicken gpr39 (95.5%) and moderate homology to mouse (64.7%), rat (63.7%), a ...200717954600
analysis of polymorphisms in the insulin-like growth factor 1 receptor (igf1r) gene from japanese quail selected for body weight.insulin-like growth factor 1 receptor (igf1r) is essential for the signalling of growth. in this study, we performed single nucleotide polymorphism (snp) detection in the japanese quail igf1r coding region and an association study between snps and body weight in two lines (ss and ll) selected for large and small body weight. of 21 snps obtained, a snp at position ab292766:c.2293g>a led to the replacement of a valine with an isoleucine (v765i). the two lines were fixed for alternate alleles, with ...200717956593
effect of methimazole-induced hypothyroidism on adrenal and gonadal functions in male japanese quail (coturnix japonica).to investigate the effect of hypothyroidism on gonadal and adrenal functions in male japanese quail (coturnix japonica), hypothyroidism was induced in male adult japanese quail by daily administration of 2-mercapto-1-methylimidazole (methimazole) in their drinking water. four weeks after methimazole treatment, the japanese quail were sacrificed, and the plasma concentrations of free triiodothyronine (ft3), free thyroxine (ft4), total t3 (tt3), total t4 (tt4), corticosterone, testosterone, lh and ...200717965543
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