Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| the routine cultural identification of microsporum ringworm of the scalp. | 1949 | 18135877 | |
| [not available]. | 1949 | 18138261 | |
| [not available]. | 1949 | 18147772 | |
| ringworm of the scalp due to microsporum audouini during pregnancy. | 1949 | 18151077 | |
| the local treatment of tinea capitis due to microsporum audouini. | 1949 | 18151228 | |
| dna microarray based on arrayed-primer extension technique for identification of pathogenic fungi responsible for invasive and superficial mycoses. | an oligonucleotide microarray based on the arrayed-primer extension (apex) technique has been developed to simultaneously identify pathogenic fungi frequently isolated from invasive and superficial infections. species-specific oligonucleotide probes complementary to the internal transcribed spacer 1 and 2 (its1 and its2) region were designed for 24 species belonging to 10 genera, including candida species (candida albicans, candida dubliniensis, candida famata, candida glabrata, candida tropical ... | 2008 | 18160452 |
| microsporum canis in a neonatal intensive care unit patient. | a 45-day-old male neonate (born 25 weeks and 5 days) presented with an annular, erythematosquamous eruption covering the head, neck, trunk, upper limbs and thighs. the eruption most resembled tinea corporis, however unusual the setting. routine fungal culture grew microsporum canis. no contacts could be identified. no previous case of tinea corporis had been seen in this neonatal unit, and very few reports are in the literature, particularly regarding this zoophilic organism. our patient cleared ... | 2008 | 18186843 |
| collection of fungi samples from nails: comparative study of curettage and drilling techniques. | onychomycosis is a common problem. obtaining a positive laboratory test before treatment is important in clinical practice because the treatment of onychomycosis requires expensive oral antifungal therapy with potentially serious side-effects. | 2008 | 18211411 |
| rapid identification and differentiation of trichophyton species, based on sequence polymorphisms of the ribosomal internal transcribed spacer regions, by rolling-circle amplification. | dna sequencing analyses have demonstrated relatively limited polymorphisms within the fungal internal transcribed spacer (its) regions among trichophyton spp. we sequenced the its region (its1, 5.8s, and its2) for 42 dermatophytes belonging to seven species (trichophyton rubrum, t. mentagrophytes, t. soudanense, t. tonsurans, epidermophyton floccosum, microsporum canis, and m. gypseum) and developed a novel padlock probe and rolling-circle amplification (rca)-based method for identification of s ... | 2008 | 18234865 |
| antibacterial and antifungal activities of andrachne cordifolia muell. | the crude methanolic extract of andrachne cordifolia muell. (euphorbiaceae) and its various fractions in different solvent systems (chloroform, ethyl acetate and n-butanol) were screened for antibacterial and antifungal activities. crude extract and subsequent fractions demonstrated moderate to excellent antibacterial activities against the tested pathogens. highest antibacterial activity was displayed by both chloroform and ethyl acetate fractions (100%) followed by the crude extract (68%) agai ... | 2007 | 18237026 |
| dermatophytoses in outpatients attending the dermatology center of avicenna hospital in qazvin, iran. | dermatophytosis is still being considered as one of the major public health problems in many parts of the world. to identify the prevalence and etiological agents of dermatophytoses, a study was carried out between 2004 and 2006. out of 1023 subjects suspected to have cutaneous mycoses, 348 (34%) patients were affected with dermatophytoses. the causative agents were identified macroscopically and microscopically after the clinical samples were subjected to potassium hydroxide examination and cul ... | 2008 | 18254753 |
| an epidemiological survey of tinea capitis in sarajevo, bosnia and herzegovina over a 10-year period. | the aim of this study was to determine the incidence and aetiological agents of tinea capitis in sarajevo area, bosnia and herzegovina, during a 10-year period (1997-2006). a total of 707 patients with suspected dermatophyte infections of scalp was analysed. tinea capitis was determined in 241 (34.1%) of these patients, in whom causative agents were identified in 209 (29.6%). zoophilic dermatophytes (91.8%) prevailed over anthropophilic (7.2%) and geophilic (1.0%) dermatophytes. microsporum cani ... | 2008 | 18254754 |
| comparison of hairbrush, toothbrush and cotton swab methods for diagnosing asymptomatic dermatophyte scalp carriage. | tinea capitis may also present as a minimal infection, termed carrier state. anthropophilic dermatophytes (i.e. trichophyton tonsurans and trichophyton violaceum) have been generally associated with high rates of asymptomatic carriage. | 2008 | 18269603 |
| characteristics of superficial fungal infections in the riyadh region of saudi arabia. | the prevalence and characteristics of superficial fungal infections (sfis) vary with climatic conditions, lifestyle, and population migration patterns. this study was undertaken to determine the characteristics of sfis amongst patients visiting the dermatology clinic of riyadh military hospital, riyadh, saudi arabia, during the period 2003-2005. | 2008 | 18289321 |
| molecular detection of microsporum persicolor in soil suggesting widespread dispersal in central india. | a survey was conducted from 1999 to 2003 as part of a microbial biodiversity study on geophilic and keratinophilic fungi in central india. among the keratinophilic fungi recovered were 82 isolates belonging to the dermatophyte genus microsporum. species were provisionally identified by morphology and confirmed by pcr-rflp and sequencing of the its regions of rdna. microsporum persicolor appeared to be preponderant in central indian soils, outnumbering the common geophilic species of microsporum ... | 2008 | 18297545 |
| antifungal activity of essential oils of croton species from the brazilian caatinga biome. | to find new antifungal agents among essential oils from brazilian croton species. | 2008 | 18298533 |
| frequency of yeasts and dermatophytes from healthy and diseased dogs. | the aim of this study was to investigate the presence of dermatophytes and yeasts in healthy and diseased dogs. a total of 633 samples were collected from 26 healthy animals (104 samples), 131 with dermatitis (343 samples), 74 with otitis (148 samples), and 19 with ocular diseases (38 samples). cultures from healthy animals were positive for malassezia pachydermatis in 13.5% (7/52) of samples from skin, 42.3% (11/26) from ear, and 3.8% (1/26) from eye. fungal growth was observed in 20.4% (70/343 ... | 2008 | 18319432 |
| [tinea capitis]. | tinea capitis is a widespread scalp infection in children caused by dermatophytes. in fact, it is the most common cutaneous mycosis in children but is uncommon in adults. the disease has been major public health concern for decades. some factors implicated in infection include poor personal hygiene, crowded living conditions, and low socioeconomic status. it can be caused by any pathogenic dermatophyte except for epidermophyton floccosum and trichophyton concentricum. trichophyton rubrum, the mo ... | 2008 | 18346430 |
| terbinafine hydrochloride oral granules versus oral griseofulvin suspension in children with tinea capitis: results of two randomized, investigator-blinded, multicenter, international, controlled trials. | although griseofulvin is currently considered the primary antifungal agent used to treat tinea capitis in many countries, increasingly higher doses and longer durations of treatment are becoming necessary to achieve effective treatment. alternative antifungal therapies with shorter/simpler treatment regimens may be important to develop for this indication. | 2008 | 18378354 |
| evaluation of novel broad-range real-time pcr assay for rapid detection of human pathogenic fungi in various clinical specimens. | in the present study, a novel broad-range real-time pcr was developed for the rapid detection of human pathogenic fungi. the assay targets a part of the 28s large-subunit ribosomal rna (rdna) gene. we investigated its application for the most important human pathogenic fungal genera, including aspergillus, candida, cryptococcus, mucor, penicillium, pichia, microsporum, trichophyton, and scopulariopsis. species were identified in pcr-positive reactions by direct dna sequencing. a noncompetitive i ... | 2008 | 18385440 |
| in vitro antifungal activity of extracts and neolignans from piper regnellii against dermatophytes. | the present study was designated to evaluate the in vitro antidermatophyte activity of extracts from leaves of piper regnellii as well as of the bioactivity-directed isolation of neolignans. the antifungal assay was performed by microdilution techniques. the hydroalcoholic extract of piper regnellii leaves presented a strong activity against the dermatophyte fungi trichophyton mentagrophytes, trichophyton rubrum, microsporum canis and microsporum gypseum with mics of 15.62, 15.62, 15.62 and 62.5 ... | 2008 | 18394835 |
| ultraviolet c inactivation of dermatophytes: implications for treatment of onychomycosis. | onychomycosis responds to systemic antifungals and sometimes to topical lacquers, but alternative treatments are desirable. topical application of germicidal ultraviolet (uv) c radiation may be an acceptable and effective therapy for infected nails. | 2008 | 18410410 |
| experimental guinea pig model of dermatophytosis: a simple and useful tool for the evaluation of new diagnostics and antifungals. | the aim of this study was to establish a simple guinea pig model for the purpose of evaluating diagnostic principles and treatment modalities for dermatophytic infections. the following variables were evaluated; pre-treatment of the skin by shaving versus tape stripping, microsporum canis or trichophyton mentagrophytes test strains as etiologic agents, differences in inoculum concentrations, and inoculation with and without occlusion. the course of infection was evaluated clinically by redness a ... | 2008 | 18415837 |
| screening of chemical composition, antimicrobial and antioxidant activities of artemisia essential oils. | the chemical composition of essential oils isolated from aerial parts of seven wild sages from western canada -artemisia absinthium l., artemisia biennis willd., artemisia cana pursh, artemisia dracunculus l., artemisia frigida willd., artemisia longifolia nutt. and artemisia ludoviciana nutt., was investigated by gc-ms. a total of 110 components were identified accounting for 71.0-98.8% of the oil composition. high contents of 1,8-cineole (21.5-27.6%) and camphor (15.9-37.3%) were found in arte ... | 2008 | 18417176 |
| tinea capitis among primary school children in anambra state of nigeria. | tinea capitis continues to be a common problem of infancy and childhood, particularly among those living in unhygienic crowded conditions. the prevalence and aetiology of tinea capitis have not been well defined in anambra state of nigeria - hence the need to undertake this study. a total of 47,723 primary school children residing in different regions of the state was screened for tinea capitis between 2002 and 2005. of this number, 4498 (9.4%) had tinea capitis. the highest prevalence of the di ... | 2008 | 18422917 |
| preanalytical conditions for broth microdilution antifungal susceptibility of microsporum spp. | dermatophytoses caused by the genus microsporum require a long-duration therapy compared to infections caused by other genera. treatment of these cutaneous infections includes topical and systemic antifungal agents. tinea capitis and tinea unguium caused by m. canis and m. gypseum are the most difficult-to-treat dermatophytoses. there are few specific studies about corresponding antifungal susceptibility in vitro. recently, the clinical and laboratory standards institute proposed the m38a docume ... | 2008 | 18422920 |
| tinea capitis among primary school children in some parts of central nigeria. | tinea capitis is the most common superficial mycosis in children of school age. although it is of public health importance, it is not a reportable or notifiable disease; therefore, actual prevalence figures are unknown in many endemic areas. the aim of this work was to determine the prevalence of tinea capitis among primary school children in two states in central nigeria, highlighting the main aetiological agents of the infection and possible predisposing factors. a total of 28 505 primary scho ... | 2008 | 18422924 |
| use of a sustained release preparation of clotrimazole to treat dermatophytosis in a siamang (hylobates syndactylus). | in november 2004, an adult male siamang (hylobates syndactylus) from the tisch family zoological gardens-jerusalem biblical zoo (israel) presented with skin lesions on various body parts. lesions consisted of alopecia and dry, crusty areas of hyperkeratosis. a diagnosis of dermatophytosis due to microsporum canis was determined by fungal culture of skin scraping taken from the edge of several lesions. treatment with various oral and topical antifungal agents such as griseofluvin, itraconozole, a ... | 2008 | 18432106 |
| identification of dermatophytes by sequence analysis of the rrna gene internal transcribed spacer regions. | identification of dermatophytes using the traditional method is sometimes problematic because of atypical microscopic or macroscopic morphology. the aim of this study was to evaluate the feasibility of using sequencing of the ribosomal internal transcribed spacer (its)1 and its2 regions for identification of 17 dermatophyte species. the its regions of 188 strains (62 reference strains and 126 clinical isolates) were amplified by pcr and sequenced. species identification was made by sequence comp ... | 2008 | 18436592 |
| [investigation of the agents and risk factors of dermatophytosis: a hospital-based study]. | the aims of this study were the detection of distribution of dermatophyte species isolated from the clinical samples of patients with dermatophytosis and the evaluation of risk factors for the development of dermatophytosis. a total of 441 skin, nail and scalp/hair specimens obtained from 301 patients (151 were male; age range 2 months-80 years, median 42 years) and 884 foot and hand skin and nail specimens obtained from 221 control subjects (110 were male; age range 5-75 years, median 36 years) ... | 2008 | 18444566 |
| confirmed case of feline mycetoma due to microsporum canis. | the first case of feline true mycetoma because of a dermatophyte has been reported in this manuscript, although pseudomycetoma has been described in dogs and cats. the patient was a 9-year-old castrated male persian cat weighing 4.2 kg with subcutaneous nodules on the dorsal trunk. physical examination revealed two subcutaneous nodules (2.5 x 5.0 cm and 3.5 x 5.0 cm in size) that drained purulent exudates with cement-like substances containing yellowish granules. the impression smear of the yell ... | 2009 | 18444972 |
| in vitro antifungal activity of 2-(4-substituted phenyl)-3(2h)-isothiazolones. | the in vitro antifungal activity of several n2-phenyl-3(2h)-isothiazolones substituted at c4 of the phenyl moiety with heterocyclic nucleus or groups of different physico-chemical properties against four human pathogenic fungi was determined by broth macrodilution method; results were compared with those obtained with itraconazole and ketoconazole. these isothiazolones showed moderate to high activity against some or all tested strains and in comparison with the reference drugs, 5-chloro-2-(4-ni ... | 2007 | 18450218 |
| meta-analysis: griseofulvin efficacy in the treatment of tinea capitis. | despite its long history in clinical use, reported efficacy rates of griseofulvin remain highly variable. a meta-analysis of clinical trials of griseofulvin use in tinea capitis was performed to determine mean griseofulvin efficacy. a review of the literature identified 7 studies. when all 7 studies were pooled, the overall mean effective cure (negative koh and culture) of griseofulvin at 4 to 6 weeks posttreatment was 73.4% +/- 7% (7 studies, n = 438 patients). higher efficacy rates appeared to ... | 2008 | 18459518 |
| synthesis and biological activity of peptide derivatives of iodoquinazolinones/nitroimidazoles. | two substituted quinazolinyl/imidazolyl-salicylic acids 5, 6 were synthesized by the reaction of 6-iodo-2-methylbenzoxazin-4-one/5-nitroimidazole with 5-aminosalicylic acid (5-asa). coupling of compounds 5 and 6 with different amino acid ester hydrochlorides, dipeptide and tripeptide methyl esters yielded novel quinazolino/imidazolopeptide derivatives 5a-f and 6a-g. the chemical structures of all newly synthesized compounds were confirmed by means of ft-ir, (1)h- and (13)c-nmr, msand elemental a ... | 2008 | 18463598 |
| [dermatophytes isolated in hospital universitario 12 de octubre (madrid, spain).]. | over a 10 year period (january 1988 - december 1997), 3,241 dermatophyte strains were isolated from 18,465 specimens from patients in whom dermatophytosis was suspected clinically. this represents a 17.5% rate of isolation. trichophyton rubrum (38.44%), microsporum canis (28.75%), epidermophyton floccosum (14.5%) and trichophyton mentagrophytes (13.5%) were the dominant species, and trichophyton tonsurans (2.09%) has emerged, whilst in the previous decade it had virtually disappeared. our study ... | 1999 | 18473578 |
| [mycological view of dermatophytes in humans.]. | dermatophytes are a group of closely related fungi that have the capacity to invade keratinized tissue (skin, hair, and nails) of humans and animals to produce an infection, dermatophytosis, commonly referred to as ringworm. dermatophytoses are common of world wide: in the united states, microsporum audouinii and microsporum canis, once the major agents of tinea capitis, have been superseded by trichophyton tonsurans. since the 1950s, t. tonsuranshas advanced from mexico and the caribbean and is ... | 1999 | 18473586 |
| [on the epidemiology of dermatophytoses in granada (andalousia, spain).]. | one hundred and fourteen dermatophytes were isolated during the period from january 1995 to may 1997 in our outpatient's center of dermatology, at the universitary hospital of granada. trichophyton rubrum (35.96%) was the commonest species, followed by trichophyton mentagrophytes (21.19%) and microsporum canis (21.19%). on the clinical ground, tinea unguium (24.56%) was predominant, with tinea corporis (23.68%) and also tinea capitis (2192 %). our results are compared with recent data from other ... | 1999 | 18473602 |
| reconstructed interfollicular feline epidermis as a model for the screening of antifungal drugs against microsporum canis. | a fully differentiated reconstructed interfollicular feline epidermis (rfe) was recently developed in vitro. it was shown to be relevant for the study of microsporum canis-epidermal interactions. in this study, rfe was evaluated as a potential model for the in vitro screening of drugs against m. canis. as a preliminary step, the minimum inhibitory concentration of miconazole nitrate against m. canis ihem 21239 grown on sabouraud's dextrose agar was determined to be 0.3 microg ml(-1). rfe grown a ... | 2008 | 18477328 |
| immunoprophylaxis of dermatophytosis in animals. | dermatophytosis is a relatively common disease in many countries occurring endemically both in companion and food animals. fungi belonging to the genera trichophyton and microsporum are most often isolated from clinical cases. measures to control and prevent dermatophytosis include sanitation, hygienic measures and treatment. in some countries, successful control and eradication have been achieved by mass vaccination of cattle and fur-bearing animals. vaccines containing live attenuated cells of ... | 2008 | 18478355 |
| secreted proteases from dermatophytes. | dermatophytes are highly specialized pathogenic fungi that exclusively infect the stratum corneum, nails or hair, and it is evident that secreted proteolytic activity is important for their virulence. endo- and exoproteases-secreted by dermatophytes are similar to those of species of the genus aspergillus. however, in contrast to aspergillus spp., dermatophyte-secreted endoproteases are multiple and are members of two large protein families, the subtilisins (serine proteases) and the fungalysins ... | 2008 | 18478360 |
| pathogenesis of dermatophytosis. | despite the superficial localization of most dermatophytosis, host-fungus relationship in these infections is complex and still poorly elucidated. though many efforts have been accomplished to characterize secreted dermatophytic proteases at the molecular level, only punctual insights have been afforded into other aspects of the pathogenesis of dermatophytosis, such as fungal adhesion, regulation of gene expression during the infection process, and immunomodulation by fungal factors. however, ne ... | 2008 | 18478361 |
| dermatophytoses in animals. | dermatophytoses are one of the most frequent skin diseases of pets and livestock. contagiousness among animal communities, high cost of treatment, difficulty of control measures, and the public health consequences of animal ringworm explain their great importance. a wide variety of dermatophytes have been isolated from animals, but a few zoophilic species are responsible for the majority of the cases, viz. microsporum canis, trichophyton mentagrophytes, trichophyton equinum and trichophyton verr ... | 2008 | 18478363 |
| updates on the epidemiology of dermatophyte infections. | the spectrum of dermatophytes isolated from skin lesions had changed in last 70 years. before the second world war in germany, microsporum audouinii and epidermophyton floccosum ranked the first, whereas trichophyton rubrum is the most common dermatophyte since the fifties of last century, accounting for 80-90% of the strains, followed by t. mentagrophytes. this evolution is typical for central and north europe and it needs to be connected with the increase in the incidence of tinea pedis. in co ... | 2008 | 18478365 |
| the significance of itraconazole for treatment of fungal infections of skin, nails and mucous membranes. | itraconazole is an antifungal drug from the triazole group with distinct in vitro activity against dermatophytes, yeasts and some molds. itraconazole has a primarily fungistatic activity. itraconazole accumulates in the stratum corneum and in nail material due to its high affinity to keratin, as well as in sebum and vaginal mucosa. together with terbinafine and fluconazole, itraconazole belongs to the modern highly effective systemic antifungal drugs with a favorable risk-benefit ratio and for t ... | 2009 | 18479501 |
| microsporum gypseum infection in the siena area in 2005-2006. | fourteen cases of dermatophytosis caused by microsporum gypseum, representing 6.8% of all dermatophytic infections reported, were diagnosed in siena, italy, between 2005 and 2006. there were as follows: six cases of tinea corporis, one case of tinea corporis associated with tinea capitis, one case of tinea corporis associated with tinea barbae, one kerion on the head, one tinea cruris, one tinea faciei, one tinea barbae, two onychomycosis. in the three subjects with tinea corporis, the clinical ... | 2009 | 18498297 |
| childhood dermatomycoses study in sfax hospital, tunisia. | mycoses are frequent affections in childhood. fungal type varies according to the age and the affected organ. the aim of this study was to determine the aetiological agents of childhood dermatomycoses and to draw attention to the diversity of their clinical manifestations. retrospective study dealing with children's cases with age <16-year old and having dermatomycosis diagnosed between 1991 and 2005 at the parasitology and mycology laboratory of sfax university hospital. a total of 4559 childre ... | 2008 | 18498308 |
| susceptibility of dermatophyte isolates obtained from a large worldwide terbinafine tinea capitis clinical trial. | our group, in collaboration with seven other laboratories, has recently developed a method to determine the susceptibility of dermatophytes. | 2008 | 18510668 |
| common tinea infections in children. | the common dermatophyte genera trichophyton, microsporum, and epidermophyton are major causes of superficial fungal infections in children. these infections (e.g., tinea corporis, pedis, cruris, and unguium) are typically acquired directly from contact with infected humans or animals or indirectly from exposure to contaminated soil or fomites. a diagnosis usually can be made with a focused history, physical examination, and potassium hydroxide microscopy. occasionally, wood's lamp examination, f ... | 2008 | 18533375 |
| antimicrobial activity of brazilian copaiba oils obtained from different species of the copaifera genus. | the antimicrobial activity of copaiba oils was tested against gram-positive and gram-negative bacteria, yeast, and dermatophytes. oils obtained from copaifera martii, copaifera officinalis, and copaifera reticulata (collected in the state of acre) were active against gram-positive species (staphylococcus aureus, methicillin-resistant s. aureus, staphylococcus epidermidis, bacillus subtilis, and enterococcus faecalis) with minimum inhibitory concentrations ranging from 31.3-62.5 microg/ml. the oi ... | 2008 | 18545856 |
| microbial and xanthine dehydrogenase inhibitory activity of some flavones. | xanthine dehydrogenase (xdh) is responsible for the pathological condition called gout. in the present study different flavones synthesized from chalcone were evaluated in vitro for their inhibitory activity. inhibitory activity of flavones on xdh was determined in terms of inhibition of uric acid synthesis from xanthine. the enzymatic activity was found maximum at ph 7.5 and temperature 40 degrees c. the flavones 6-chloro-2-[3-(4-hydroxy-phenyl)-1-phenyl-1-h-pyrazol-4-yl]-chromen-4-one (f(1)) a ... | 2008 | 18569337 |
| in vitro activity of penicillium chrysogenum antifungal protein (paf) and its combination with fluconazole against different dermatophytes. | strains of five dermatophyte species (microsporum canis, microsporum gypseum, trichophyton mentagrophytes, trichophyton rubrum and trichophyton tonsurans) were selected for testing against penicillium chrysogenum antifungal protein (paf) and its combination with fluconazole (fcz). inhibition of microconidia germination and growth was detected with mics of paf ranging from 1.56 to 200 microg ml(-1) when it was used alone, or at constant concentration (100 microg ml(-1)) in combination with fcz at ... | 2008 | 18574706 |
| single-step pcr using (gaca)4 primer: utility for rapid identification of dermatophyte species and strains. | dermatophytes are fungi that belong to three genera: epidermophyton, microsporum, and trichophyton. identification of dermatophyte species is essential for appropriate diagnosis and treatment of dermatophytosis. routine identification depends on macroscopic and microscopic morphology, which is time-consuming and does not identify dermatophyte strains. in this study, two pcr-based methods were compared for their abilities to identify 21 dermatophyte isolates obtained from egyptian patients to the ... | 2008 | 18579714 |
| high prevalence of tinea capitis in newly arrived migrants at an english-language school, melbourne, 2005. | to investigate a reported increase in tinea capitis in an english-language school to determine if it was an outbreak and whether control measures were warranted. | 2008 | 18601634 |
| synthesis of organometallic-based biologically active compounds: in vitro antibacterial, antifungal and cytotoxic properties of some sulfonamide incorporated ferrocences. | sulfonamides incorporated ferrocene (sif) have been synthesized by the condensation reaction of sulfonamides (sulfanilamide, sulfathiazole or sulfamethaxazole) with 1,1'-diacetylferrocene. the synthesized compounds (sif(1)-sif(4)) have been characterized by their physical, spectral and analytical properties and have been screened for their in vitro antibacterial properties against pathogenic bacterial strains e.g., escherichia coli, pseudomonas aeruginosa, bacillus subtilis staphylococcus aureus ... | 2009 | 18608785 |
| changes in frequency of agents of tinea capitis in school children from western china suggest slow migration rates in dermatophytes. | tinea capitis is a common dermatophyte infection of the scalp of children in western china, with the gray-patch from being the most prevalent. twenty years ago, the most widespread etiologic agent was reported to be trichophyton violaceum, which was later succeeded by microsporum ferrugineum and trichophyton schoenleinii. in the framework of our recent study, 97 isolates were collected from patients with clinically suspected tinea capitis. identification was performed by conventional methods and ... | 2008 | 18608883 |
| in vitro activity of cay-1, a saponin from capsicum frutescens, against microsporum and trichophyton species. | dermatomycoses are among the world's most common diseases and their incidence has increased over recent years, particularly in immunosuppressed patients. in previous studies, the saponin cay-1 from cayenne pepper (capsicum frutescens), has shown antifungal activities against candida albicans and aspergillus spp. we therefore studied the in vitro antifungal activity of cay-1 against non-germinating conidia and hyphae of clinical isolates of the dermatophytes trichophyton mentagrophytes, t. rubrum ... | 2008 | 18608885 |
| the emergence of trichophyton tonsurans in port-au-prince, haiti. | the occurrence of the anthropophilic dermatophyte trichophyton tonsurans as a frequent causative agent of tinea capitis in several developed countries has been associated with a global rise in its isolation during recent years. while t. tonsurans was never found in haiti before 1988, a sharp increase in the number of isolates of this species from scalp lesions began to be observed in 2005 in port-au-prince, haiti. a prospective study was conducted in port-au-prince from may to november 2006 of 6 ... | 2009 | 18608887 |
| antimicrobial activities of gloriosa superba linn (colchicaceae) extracts. | the methanol extract of the rhizomes of gloriosa superba linn (colchicaceae) and its subsequent fractions in different solvent systems were screened for antibacterial and antifungal activities. excellent antifungal sensitivity was expressed by the n-butanol fraction against candida albicans and candida glaberata (up to 90%) and against trichophyton longifusus (78%) followed by the chloroform fraction against microsporum canis (80%). in the antibacterial bioassay, the crude extract and subsequent ... | 2008 | 18615278 |
| unexpected formation of 3-chloro-1-hydroxy-2,6-diarylpiperidin-4-ones: synthesis, antibacterial and antifungal activities. | new 3-chloro-1-hydroxy-2,6-diarylpiperidin-4-ones 18-22 were synthesized, characterized by melting point, elemental analysis, ms, ft-ir, one-dimensional nmr ((1)h & (13)c) spectroscopic data and evaluated for their in vitro antibacterial and antifungal activities. all the newly synthesized compounds exerted a wide range of antibacterial activities against the entire tested gram-positive and gram-negative bacterial strains except escherichia coli. compounds 21 and 22 exerted strong antifungal act ... | 2009 | 18622879 |
| pseudomembranous-like tinea of the scrotum: report of six cases. | six cases of tinea of the scrotum with atypical clinical features were observed in the dermatology department of our hospital between 2001 and 2007. the age of onset ranged from 14 to 26 years. unusual clinical presentations of pseudomembranous-like disease were observed in every patient. causative agents were microsporum gypseum in five patients and trichophyton rubrum in one patient. three of the m. gypseum isolates had atypical morphologies. all six isolates were identified by cultural morpho ... | 2009 | 18627470 |
| [history and description of microsporum fulvum, a valid species of this genus discovered in argentina]. | 2008 | 18669053 | |
| dysgonic strain of microsporum canis pseudomycetoma in a domestic long-hair cat. | a 4-year-old domestic long-hair cat was presented with two large non-painful, ulcerated and suppurative lesions over the flanks. histopathology and cytology were consistent with fungal pyogranulomatous inflammation. culture of tissue yielded a dysgonic strain of microsporum canis. the cat was treated successfully by staged en bloc resections of the lesions, followed by oral ketoconazole, then oral terbinafine. this is the first reported case of dermatophytic pseudomycetoma in a domestic long-hai ... | 2008 | 18673475 |
| an antifungal property of crude plant extracts from anogeissus leiocarpus and terminalia avicennioides. | chloroform, ethanolic, methanolic, ethyl acetate and aqueous root extracts of anogeissus leiocarpus and terminalia avicennioides were investigated in vitro for antifungal activities against aspergillus niger, aspergillus fumigatus, penicillium species, microsporum audouinii and trichophyton rubrum using radial growth technique. the plant extracts inhibited the growth of all the test organisms. the minimum inhibitory concentration (mic) of the extracts ranged between 0.03 microg/ml and 0.07 micro ... | 2008 | 18680963 |
| a lufenuron pre-treatment may enhance the effects of enilconazole or griseofulvin in feline dermatophytosis? | the effectiveness of enilconazole (4 weekly rinses with a 0.2% solution) or griseofulvin (50mg/kg twice daily for 40 days) following a pre-treatment with oral lufenuron (100mg/kg by-weekly for 8 weeks) was tested on 25 (11+14) microsporum canis infected cats. control animals were treated with lufenuron, griseofulvin and enilconazole alone. at day 150 pre-treated animals were culturally negative and clinically cured. while lufenuron alone was found to be ineffective against m canis infection, an ... | 2009 | 18684653 |
| microbiological and histopathological features of canine acral lick dermatitis. | the purpose of this study was to investigate microbiological and histopathological features of canine acral lick dermatitis (ald). microbial characteristics of ald are poorly described in current literature. if infection is recognized, antimicrobial selection is usually empirical, based on appearance, cytology or surface culture, rather than deep tissue culture. it was hypothesized that cultures obtained from deep tissue would yield different results than predicted by surface culture and cytolog ... | 2008 | 18699812 |
| pets as the main source of two zoonotic species of the trichophyton mentagrophytes complex in switzerland, arthroderma vanbreuseghemii and arthroderma benhamiae. | in cases of highly inflammatory dermatophytosis in humans, it is important to identify the possible source of animal transmission in order to prevent recurrence, family outbreaks or rapidly progressing epidemics. a survey of dermatophytes in pets during a 14-month period in switzerland revealed, in addition to microsporum canis, two different species of the trichophyton mentagrophytes complex, arthroderma benhamiae and arthroderma vanbreuseghemii, all causing inflammatory dermatophytoses. arthro ... | 2009 | 18699813 |
| secreted subtilisins of microsporum canis are involved in adherence of arthroconidia to feline corneocytes. | microsporum canis is a pathogenic fungus that causes a superficial cutaneous infection called dermatophytosis, mainly in cats and humans. the mechanisms involved in adherence of m. canis to epidermis have never been investigated. here, a model was developed to study the adherence of m. canis to feline corneocytes through the use of a reconstructed interfollicular feline epidermis (rfe). in this model, adherence of arthroconidia to rfe was found to be time-dependent, starting at 2 h post-inoculat ... | 2008 | 18719187 |
| validation of pcr-reverse line blot, a method for rapid detection and identification of nine dermatophyte species in nail, skin and hair samples. | a dermatophyte-specific pcr-reverse line blot (pcr-rlb) assay based on internal transcribed sequences was developed. this assay allows the rapid detection and identification of nine clinically relevant species within the three dermatophyte genera trichophyton, microsporum and epidermophyton in nail, skin and hair samples within 1 day. analysis of 819 clinical samples (596 nail, 203 skin and 20 hair) revealed a positive pcr-rlb result in 93.6% of 172 culture-positive and microscopy-positive sampl ... | 2008 | 18727802 |
| design, synthesis, and antifungal activity of triazole and benzotriazole derivatives. | this study describes the design, synthesis and evaluation of a novel series of 1,2,4-triazole and benzotriazole derivatives as inhibitors of cytochrome p450 14alpha-demethylase (14dm). the chemical structures of the new compounds were confirmed by elemental and spectral ((1)h nmr, (13)c nmr, mass) analyses. compounds were designed by a generating virtual library of compounds and docking them into the enzyme active site. furthermore, they were found to have in vitro activity against microsporum c ... | 2009 | 18760508 |
| pramiconazole, a triazole compound for the treatment of fungal infections. | pramiconazole from barrier therapeutics inc is a new addition to the family of triazole antifungal agents that act by inhibiting fungal cell membrane ergosterol synthesis, thereby leading to increased cell permeability and destruction. barrier therapeutics was developing an oral formulation of pramiconazole for the potential treatment of seborrheic dermatitis (erythematosquamous skin disease), onychomycosis and dermatomycosis (including tinea versicolor, tinea pedis and tinea cruris/corporis). i ... | 2008 | 18763217 |
| biological activity of two related triterpenes isolated from combretum nelsonii (combretaceae) leaves. | antifungal bioassay-guided fractionation of combretum nelsonii leaf extracts afforded two closely related triterpenes, asiatic acid and arjunolic acid. antifungal activities of the mixture of asiatic acid and arjunolic acid were determined against five fungal animal pathogens. the minimum inhibitory concentrations of the mixture to the different pathogens varied from 0.2 to 1.6 microg ml(-1); candida albicans (0.9 microg ml(-1)), cryptococcus neoformans (0.4 microg ml(-1)), aspergillus fumigatus ... | 2008 | 18780249 |
| epidemiological trends in skin mycoses worldwide. | fungal infections of the skin and nails are a common global problem. the high prevalence of superficial mycotic infections shows that 20-25% of the world's population has skin mycoses, making these one of the most frequent forms of infection. pathogens responsible for skin mycoses are primarily anthropophilic and zoophilic dermatophytes from the genera trichophyton (t.), microsporum (m.) and epidermophyton (e.). there appears to be considerable inter- and intra-continental variability in the glo ... | 2008 | 18783559 |
| the advantages of topical combination therapy in the treatment of inflammatory dermatomycoses. | dermatomycoses are contagious superficial fungal infections, which are highly prevalent in developed and developing countries. caused by a range of epidermophyton, microsporum and trichophyton species, dermatomycoses manifest on glabrous skin as 'ringworm', an annular scaly lesion with a variable inflammatory component. itch is the chief subjective symptom, particularly in tinea cruris. unless lesions are extensive or resistant to local therapy, dermatomycoses of glabrous skin are treated with t ... | 2008 | 18783560 |
| [synergy between ajoene and ketoconazole in isolates of microsporum canis. a preliminary study using fractional inhibitory concentration technique (fic)]. | fungal infections are probably the most frequent infectious diseases affecting human being. resistance to different anti-fungal drugs, and their bioavailability in the infection site, represent a problem for treatment. looking for effective solutions, combination of two or more antifungal drugs to obtain an additive effect or synergic effect that potent antifungal activity has been investigated. in this study, the effect (additive, antagonist or synergistic) of ajoene and ketoconazole combinatio ... | 2008 | 18785785 |
| tinea capitis in southwest poland. | tinea capitis in southwest poland is mainly caused by zoophilic dermatophytes. microsporum canis is the main pathogen, which was demonstrated in all analysed periods between 1977 and 2006 (50.5%-63.2%). recently (2002-2006), a significant (p < 0.05) increase of trichophyton tonsurans isolates was observed, which may be due to increasing migration of polish population in this period. to sum up, the data on the prevalence of tinea capitis in southwest poland resemble the epidemiological situation ... | 2009 | 18793266 |
| infectious alopecia in a dog breeder after renal transplantation. | tinea capitis rarely occurs in renal transplant recipients. we report this living-related renal transplant patient receiving cyclosporine-based therapy who initially presented with severe exfoliation of the scalp with yellowish-white scales and marked hair loss. the lesions extended to the frontal area and both cheeks, resulting in several skin ulcers with perifocal erythematous inflammatory changes, and palpable cervical lymph nodes. a biopsy of a skin lesion revealed fungal infection and cultu ... | 2008 | 18818142 |
| [antagonistic activity of bacteria from bacillus genus against dermatophyte fungi]. | antagonistic properties of the strain bacillus subtilis ib-54 with respect to dermatophyte fungi trichophyton rubrum, t. mentagrophytes var. gypseum, microsporum canis was studied. the studied strains of bacilli effectively inhibited growth and development of dermatophytes when were cultivated on the media containing different carbon sources. experiments on laboratory animals showed that b. subtilis ib-54 displayed no virulence, toxicity, and toxigenicity and can be considered as perspective obj ... | 2008 | 18819402 |
| antibacterial, antifungal, insecticidal, cytotoxicity and phytotoxicity studies on indigofera gerardiana. | the antibacterial, antifungal, acute cytotoxicity, phytotoxicity and insecticidal profile of the crude extract and various fractions of indigofera gerardiana have been studied. six bacterial and fungal strains were used, of which samonella typhi and microsporum canis were the most susceptible strains with mics 0.37 mg/ml and 0.09 mg/ml, respectively. the crude extract and the fractions showed low insecticidal activity against sitophilus oryzae, rhyzopertha dominica and callosbruchus analis but n ... | 2009 | 18825532 |
| design, synthesis, characterization and in vitro antimicrobial evaluation of 4,6-diaryl-4,5-dihydro-2-phenyl-2h-indazol-3-ols. | new 4,6-diaryl-4,5-dihydro-2-phenyl-2h-indazol-3-ols 25-32 were designed, synthesized and in vitro microbially evaluated using clinically isolated bacterial strains viz staphylococcus aureus, beta-heamolytic streptococcus, vibreo cholerae, salmonella typhii, shigella felxneri and fungal strains viz aspergillus flavus, mucor, rhizopus and microsporum gypsuem. results of this study showed that the nature of the substituents on the phenyl rings viz., methyl, methoxy, chloro, nitro as well as the br ... | 2009 | 18825556 |
| metal based isatin-derived sulfonamides: their synthesis, characterization, coordination behavior and biological activity. | some isatin derived sulfonamides and their transition metal [co(ii), cu(ii), ni(ii), zn(ii)] complexes have been synthesized and characterized. the structure of synthesized compounds and their nature of bonding have been inferred on the basis of their physical (magnetic susceptibility and conductivity measurements), analytical (elemental analyses) and spectral (ir, (1)h nmr and (13)c nmr) properties. an octahedral geometry has been suggested for co(ii), ni(ii) and zn(ii) and square-planar for cu ... | 2009 | 18825557 |
| design, synthesis and in vitro microbiological evaluation of 6,6-dimethyl-7,9-diaryl-1,2,4,8-tetraazaspiro[4.5]decan-3-thiones--a new series of 'tailor-made' compounds. | some novel 'tailor-made' compounds, 6,6-dimethyl-7,9-diaryl-1,2,4,8-tetraazaspiro[4.5]decan-3-thiones 23-27 have been studied for their in vitro antibacterial activity against staphylococcus aureus, beta-heamolytic streptococcus, vibreo cholerae, salmonella typhii, shigella felxneri, escherichia coli, klebsiella pneumonia, pseudomonas aeruginosa and anti-fungal activity against aspergillus flavus, mucor, rhizopus and microsporum gypsuem. compounds 24 and 25 exerted potent antibacterial activity ... | 2009 | 18830884 |
| in vitro anti-microbial activity of the cuban medicinal plants simarouba glauca dc, melaleuca leucadendron l and artemisia absinthium l. | in the present study, an extensive in vitro antimicrobial profiling was performed for three medicinal plants grown in cuba, namely simarouba glauca, melaleuca leucadendron and artemisia absinthium. ethanol extracts were tested for their antiprotozoal potential against trypanosoma b. brucei, trypanosoma cruzi, leishmania infantum and plasmodium falciparum. antifungal activities were evaluated against microsporum canis and candida albicans whereas escherichia coli and staphylococcus aureus were us ... | 2008 | 18949336 |
| endomelanconiopsis, a new anamorph genus in the botryosphaeriaceae. | a new lineage is discovered within the botryosphaeriaceae (ascomycetes, dothideomycetes, incertae sedis). consistent with current practice of providing generic names for independent lineages, this lineage is described as endomelanconiopsis gen. nov., with the anamorphic species e. endophytica sp. nov. and e. microspora comb. nov. (= endomelanconium microsporum). endomelanconiopsis is characterized by eustromatic conidiomata and holoblastically produced, brown, nonapiculate, unicellular conidia, ... | 2008 | 18959162 |
| dermatophyte infections in cairo, egypt. | in this study, we examined dermatophyte infections in patients referred to the department of dermatology, el-houd el-marsoud hospital, cairo, during march 2004 to june 2005. of 506 patients enrolled in this investigation, 403 (79.6%) were clinically diagnosed as having dermatophytoses (age range 6-70 years; males 240; females 163). species identification determined by observation of their macroscopic and microscopic characteristics was complemented with sequencing of the internal transcribed spa ... | 2009 | 18972221 |
| dermatophytes from urban soils in joão pessoa, paraíba, brazil. | a total of 68 soil samples was collected from "favelas" (slums), schools, public squares, beaches and vacant lots in the city of joão pessoa-pb, brazil. a search for dermatophytes in these soils was carried out by using the vanbreuseghem technique. as a result, 48 strains and 6 dermatophytes species were isolated. trichophyton terrestre (25.0%), microsporum gypseum (20.8%) and anthroderma gypsea (2.1%) were identified among the geophilic species, and t. mentagrophytes var. mentagrophytes (37.5%) ... | 2008 | 19024503 |
| hydronaphthalenones and a dihydroramulosin from the endophytic fungus psu-n24. | three new hydronaphthalenone derivatives (1-3) and one new dihydroramulosin derivative (4), were isolated from the endophytic fungus psu-n24 together with eight known compounds. their structures were elucidated by spectroscopic methods. griseofulvin (9) displayed strong antifungal activity against microsporum gypseum sh-mu-4 with a minimum inhibitory concentration (mic) value of 2 microg/ml while all metabolites exhibited very weak antibacterial activity (mic value>or=128 microg/ml) against stap ... | 2008 | 19043240 |
| secreted dipeptidyl peptidases as potential virulence factors for microsporum canis. | dermatophytoses caused by microsporum canis are frequently encountered in cats and dogs; they are highly contagious and readily transmissible to humans. in this study, two single genes, respectively coding for dipeptidyl peptidases iv and v (dppiv and dppv), were isolated and characterized. both proteins share homology with serine proteases of the s9 family, some of which display properties compatible with implication in pathogenic processes. both genes are expressed in vivo in experimentally in ... | 2008 | 19049642 |
| antimicrobial activity of iodoquinol 1%-hydrocortisone acetate 2% gel against ciclopirox and clotrimazole. | commercially available topical formulations consisting of iodoquinol 1%-hydrocortisone acetate 2%, ciclopirox 0.77%, and clotrimazole 1%-betamethasone dipropionate 0.5% were assessed for their antimicrobial activity against cultures of micrococcus luteus, propionibacterium acnes, methicillin-resistant staphylococcus aureus (mrsa), pseudomonas aeruginosa, corynebacterium aquaticum, trichophyton mentagrophytes, malassezia furfur, microsporum canis, candida albicans, trichophyton rubrum, or epiderm ... | 2008 | 19055171 |
| successful resolution of dermatophyte mycetoma following terbinafine treatment in two cats. | microsporum canis sensitive to itraconazole and terbinafine was isolated from two cats presented with generalized dermatophytosis and dermatophyte mycetoma. itraconazole therapy was withdrawn through lack of efficacy in one cat (a persian) and unacceptable adverse effects in the other (a maine coon). both cats achieved clinical and mycological cure after 12-14 weeks therapy with 26-31 mg kg(-1) terbinafine every 24 h per os (po). clinical signs in the maine coon resolved completely after 7 weeks ... | 2008 | 19055614 |
| design, synthesis, and biological evaluation of novel triazole derivatives as inhibitors of cytochrome p450 14alpha-demethylase. | based on the results of computational docking to the active site of the cytochrome p450 14alpha-demethylase (cyp51), a series of 1-(1h-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted-2-propanols as analogs of fluconazole were designed, synthesized, and evaluated as antifungal agents. the mic(80) values indicate that compounds 1a-n exhibited higher activity against nearly all fungi tested except aspergillus fumigatus than fluconazole, while compounds 2a-f, 3a-f showed no activity or onl ... | 2009 | 19097674 |
| anti-fungal efficacy of polybutylcyanoacrylate nanoparticles of allicin and comparison with pure allicin. | although garlic has been used in chinese traditional medicine for its medical properties for thousands of years, investigations into its mode of action are relatively recent. the purpose of this study was to evaluate the in vitro anti-fungal efficacy of the active principle of garlic, pure allicin and polybutylcyanoacrylate (pbca) nanoparticles (nps) loaded with allicin. pure allicin was prepared by reacting synthetic alliin with a stabilized process of the garlic enzyme alliinase. pbca nps were ... | 2009 | 19105898 |
| in vitro susceptibility of dermatophytes to conventional and alternative antifungal agents. | the minimum inhibitory concentrations (mics), the minimal fungicidal concentrations (mfcs), the fungal biomass (fb) and hyphal viability employing the dye 3-4,5 dimethyl- 2-thiazolyl- 2,5- diphenyl- 2h tetrazolium bromide (mtt) were used to compare the in vitro effects of fluconazole (flu) with those of the n-terminal palmitoyl-lipidated peptide, pal-lys-lys-nh(2) (pal), and a tea tree oil component, gamma-terpinene (ter), against several clinical isolates of microsporum canis and trichophyton r ... | 2009 | 19115137 |
| comma hairs: a dermatoscopic marker for tinea capitis: a rapid diagnostic method. | dermatoscopy and videodermatoscopy have been used for several years in the diagnosis of skin disorders. | 2008 | 19119131 |
| dermatophyte infections in patients attending a tertiary care hospital in northern italy. | we studied dermatophyte infections in patients attending the dermatology outpatients clinic of s. matteo hospital pavia, italy, during the period 2004-2006. a total of 100 samples were collected from 95 patients; 97 dermatophytes and 3 keratinophylic fungi were isolated. trichophyton rubrum was the most frequent dermatophyte isolated (42.3%), followed by microsporum canis (31%), t. mentagrophytes (14.5%) and m. gypseum (9.2%). less frequently isolated were epidermophyton floccosum and t. violace ... | 2008 | 19123311 |
| antimicrobial hasubanalactam alkaloid from stephania glabra. | a novel hasubanalactam alkaloid, named glabradine, has been isolated from the tubers of stephania glabra, together with three known quaternary protoberberine alkaloids, palmatine, dehydrocorydalmine and stepharanine. the structure of glabradine was assigned as 7-o-demethyl-n,o-dimethyloxostephinine, by means of rigorous spectroscopic analysis including 2 d nmr measurements. it was evaluated for antimicrobial activity against staphylococcus aureus, s. mutans, microsporum gypseum, m. canis and tri ... | 2009 | 19148860 |
| first case of microsporum ferrugineum from tunisia. | this is the first case of microsporum ferrugineum isolated from a tunisian patient. a 60-year-old man was admitted for tinea sycosis associated with circinate herpes of the hand. examination disclosed diffuse erythematic and perifollicular papules and pustules in the beard area. typical ringworm vesiculo-pustular lesions involved skin of the hand. isolates were identified as microsporum sp on the basis of macroscopic and microscopic colony characteristics. the diagnosis of m. ferrugineum was con ... | 2009 | 19184525 |
| [fungicidal activity of liranaftate against dermatophytes]. | the fungicidal activities of the thiocarbamate antifungal agent liranaftate were compared to those of luliconazole, amorolfine hydrochloride and ketoconazole against twelve stock strains of three species of dermatophytes. the mics of 0.001-0.009 microg/ml of luliconazole against trichophyton rubrum (n=6)were the lowest among the agents tested, but its mccs were considerably higher. consequently, the antifungal potency of luliconazole was considered fungistatic. in contrast to this, the mccs of 0 ... | 2009 | 19194054 |
| antagonism of microsporum species by soil fungi. | eighteen fungi isolated from soil by hair bating method were tested against soil inhabiting microsporum equinum, microsporum fulvum, microsporum gypseum and microsporum racemosum for their antagonistic interactions. colony inhibition during dual cultures showed inhibition of all the four microsporum species. the maximum inhibition of m. equinum, m. fulvum, m. gypseum and m. racemosum was caused by chrysosporium keratinophilum, chrysosporium tropicum, curvularia lunata and chrysosporium lucknowen ... | 2010 | 19207833 |
| epidemiology of dermatophytoses in sfax, tunisia. | the distribution of dermatophytes varies in different countries and geographical areas depending on several factors. to determine the frequency of aetiological agents and the clinical variants of dermatophytoses, we carried out a study between 1998 and 2007. out of 25 432 subjects suspected to have superficial mycoses, 9960 (39.2%) were affected with dermatophytoses; 14957 positive samples were obtained. the mean age was 35.7 years (range: 21 days to 97 years). sex ratio was 0.9. our patients we ... | 2009 | 19207834 |
| in vitro pharmacodynamic characteristics of griseofulvin against dermatophyte isolates of trichophyton tonsurans from tinea capitis patients. | tinea capitis is the most commonly observed fungal infection in childhood and is primarily caused by the dermatophyte species trichophyton tonsurans, microsporum canis, and trichophyton violaceum. in north america and the united kingdom t. tonsurans is responsible for more than 90% of cases. griseofulvin has been the treatment of choice for tinea capitis for more than 40 years and is the sole oral antifungal agent approved by the fda for the management of tinea capitis. some researchers have exp ... | 2009 | 19212895 |