Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| bacterial interactions with the eukaryotic secretory pathway. | pathogenic bacteria exploit a wide variety of host cellular processes to adhere to, invade, replicate within and damage host cells. one such process is the eukaryotic secretory pathway, in which proteins and lipids are modified and transported from the endoplasmic reticulum through the golgi network to the plasma membrane and other cellular destinations. certain bacteria secrete toxins that utilise this transport pathway to reach their cellular targets. some intracellular pathogens, including le ... | 2005 | 15694862 |
| high rate of fatal cases of pediatric septicemia caused by gram-negative bacteria with extended-spectrum beta-lactamases in dar es salaam, tanzania. | extended-spectrum beta-lactamases (esbls) were present in high proportions of escherichia coli (25% [9 of 36]) and klebsiella pneumoniae isolates (17% [9 of 52]) causing pediatric septicemia at a tertiary hospital in tanzania. patients with septicemia due to esbl-producing organisms had a significantly higher fatality rate than those with non-esbl isolates (71% versus 39%, p = 0.039). this is the first report of the ctx-m-15 genotype of esbls on the african continent and the first observation of ... | 2005 | 15695674 |
| nalidixic acid-resistant salmonella enterica serotype typhi presenting as a primary psoas abscess: case report and review of the literature. | we report an unusual case of salmonella enterica serotype typhi presenting as a primary psoas abscess. the isolate tested susceptible to ciprofloxacin but resistant to nalidixic acid in vitro, a pattern associated with fluoroquinolone therapeutic failures. we review the literature for serovar typhi psoas abscess in the absence of bacteremia and discuss the importance of identifying isolates with reduced susceptibility to fluoroquinolones. | 2005 | 15695728 |
| ifn-gamma priming of chicken heterophils upregulates the expression of proinflammatory and th1 cytokine mrna following receptor-mediated phagocytosis of salmonella enterica serovar enteritidis. | responsiveness to invasive pathogens, clearance via the inflammatory response, and activation of appropriate acquired responses are all coordinated by innate host defenses. polymorphonuclear leukocytes (pmns) are cellular components of innate response, with the primary pmn in poultry being the heterophil. priming is the potentiation of the phagocyte activation process. interferon-gamma (ifn-gamma) is a pleiotropic cytokine involved in basically all phases of immune and inflammatory responses tha ... | 2005 | 15695928 |
| purified beta-glucan as an abiotic feed additive up-regulates the innate immune response in immature chickens against salmonella enterica serovar enteritidis. | functionally, the innate immune system of immature chickens is inefficient during the first week posthatch. this immunological inefficiency enables pathogens such as salmonella enterica serovar enteritidis (se) to invade and colonize the visceral organs of immature chickens. the objective of this study was to evaluate the effect of purified beta-glucan as an immunomodulator of the innate immune response. beta-glucan, as a feed additive, significantly provided protection against se organ invasion ... | 2005 | 15698692 |
| virulence attenuation in salmonella enterica rcsc mutants with constitutive activation of the rcs system. | mutations in rcsc that result in constitutive colanic acid capsule synthesis were obtained in salmonella enterica serovar typhimurium. most rcsc alleles were dominant; however, recessive rcsc alleles were also found, in agreement with the postulated double role (positive and negative) of rcsc on the activation of the rcsb/c phosphorelay system. salmonella rcsc mutants with constitutive activation of the rcs system are severely attenuated for virulence in balb/c mice and their degree of attenuati ... | 2005 | 15699206 |
| the prevalence and antimicrobial susceptibilities of salmonella and campylobacter in ducks in taiwan. | cloacal swabs were sampled from 100 duck farms in taiwan between march 2000 and january 2001 for isolation and standard cultivation of salmonella spp. and thermophilic campylobacter spp. salmonella spp. were isolated from 4.6% (91/2000) of ducks from 20% (20/100) of duck farms. ten serotypes of salmonella enterica were identified: s. potsdam (31.9% of isolates), s. dusseldorf (18.7%), s. indiana (14.3%), s. typhimurium (7.7%), s. hadar (5.5%), s. newport (4.4%), s. derby (4.4%), s. montevideo (2 ... | 2005 | 15699587 |
| use of a recombinant salmonella enterica serovar typhimurium strain expressing c-raf for protection against c-raf induced lung adenoma in mice. | serine-threonine kinases of the raf family (a-raf, b-raf, c-raf) are central players in cellular signal transduction, and thus often causally involved in the development of cancer when mutated or over-expressed. therefore these proteins are potential targets for immunotherapy and a possible basis for vaccine development against tumors. in this study we analyzed the functionality of a new live c-raf vaccine based on an attenuated salmonella enterica serovar typhimurium aroa strain in two raf depe ... | 2005 | 15703070 |
| dissecting the phop regulatory network of escherichia coli and salmonella enterica. | genetic and genomic approaches have been successfully used to assign genes to distinct regulatory networks. however, the present challenge of distinguishing differentially regulated genes within a network is particularly hard because members of a given network tend to have similar regulatory features. we have addressed this challenge by developing a method, termed gene promoter scan, that discriminates coregulated promoters by simultaneously considering both multiple cis promoter features and ge ... | 2005 | 15703297 |
| estimate of illnesses from salmonella enteritidis in eggs, united states, 2000. | results from our model suggest that eating salmonella enterica serovar enteritidis-contaminated shell eggs caused 182,060 illnesses in the united states during 2000. uncertainty about the estimate ranged from 81,535 (5th percentile) to 276,500 illnesses (95th percentile). our model provides but 1 approach for estimating foodborne illness and quantifying estimate uncertainty. | 2005 | 15705332 |
| molecular characterization of integrons in non-typhoid salmonella serovars isolated in japan: description of an unusual class 2 integron. | to characterize class 1 and class 2 integrons among non-typhoid salmonella enterica serovars in japan, and also to monitor the spread of the multidrug-resistant s. enterica serovar typhimurium dt104. | 2005 | 15705645 |
| chloramphenicol and expression of multidrug efflux pump in enterobacter aerogenes. | chloramphenicol has been reported to act as an inducer of the multidrug resistance in escherichia coli. a resistant variant able to grow on plates containing 64 microg/ml chloramphenicol was obtained from the enterobacter aerogenes atcc 13048-type strain. chloramphenicol resistance was due to an active efflux of this antibiotic and it was associated with resistance to fluoroquinolones and tetracycline, but not to aminoglycoside or beta-lactam antibiotics. mdr in the chloramphenicol-resistant var ... | 2005 | 15707992 |
| the effect of virkon s fogging on survival of salmonella enterica and staphylococcus aureus on surfaces in a veterinary teaching hospital. | the objective of the study was to determine the disinfection efficacy of aerosolizing (cold fogging) virkon s on survival of stahpylococcus aureus and salmonella enterica on different surfaces. two experiments were conducted in different locations. salmonella enterica and s. aureus were grown in broth culture and then seeded into pre-marked areas in each location and allowed to dry. virkon s (1%) was aerosolized into the rooms (approximately 1l of per 30 m(3)). samples were collected pre- and po ... | 2005 | 15708826 |
| transcriptional regulation of the 4-amino-4-deoxy-l-arabinose biosynthetic genes in yersinia pestis. | inducible membrane remodeling is an adaptive mechanism that enables gram-negative bacteria to resist killing by cationic antimicrobial peptides and to avoid eliciting an immune response. addition of 4-amino-4-deoxy-l -arabinose (4-aminoarabinose) moieties to the phosphate residues of the lipid a portion of the lipopolysaccharide decreases the net negative charge of the bacterial membrane resulting in protection from the cationic antimicrobial peptide polymyxin b. in salmonella enterica serovar t ... | 2005 | 15710615 |
| type iii secretion of the salmonella effector protein sope is mediated via an n-terminal amino acid signal and not an mrna sequence. | type iii secretion systems (ttss) are virulence-associated components of many gram-negative bacteria that translocate bacterial proteins directly from the bacterial cytoplasm into the host cell. the salmonella translocated effector protein sope has no consensus cleavable amino-terminal secretion sequence, and the mechanism leading to its secretion through the salmonella pathogenicity island 1 (spi-1) ttss is still not fully understood. there is evidence from other bacteria which suggests that th ... | 2005 | 15716426 |
| fis regulates transcriptional induction of rpos in salmonella enterica. | the sigma factor rpos is known to regulate at least 60 genes in response to environmental sources of stress or during growth to stationary phase (sp). accumulation of rpos relies on integration of multiple genetic controls, including regulation at the levels of transcription, translation, protein stability, and protein activity. growth to sp in rich medium results in a 30-fold induction of rpos, although the mechanism of this regulation is not understood. we characterized the activity of promote ... | 2005 | 15716427 |
| cupin-type phosphoglucose isomerases (cupin-pgis) constitute a novel metal-dependent pgi family representing a convergent line of pgi evolution. | cupin-type phosphoglucose isomerases (cpgis) were identified in some archaeal and bacterial genomes and the respective coding function of cpgi's from the euryarchaeota archaeoglobus fulgidus and methanosarcina mazei, as well as the bacteria salmonella enterica serovar typhimurium and ensifer meliloti, was proven by functional overexpression. these cpgis and the cpgis from pyrococcus and thermococcus spp. represent the cpgi family and were compared with respect to kinetic, inhibitory, thermophili ... | 2005 | 15716432 |
| a chimeric n-terminal escherichia coli--c-terminal rhodobacter sphaeroides flig rotor protein supports bidirectional e. coli flagellar rotation and chemotaxis. | flagellate bacteria such as escherichia coli and salmonella enterica serovar typhimurium typically express 5 to 12 flagellar filaments over their cell surface that rotate in clockwise (cw) and counterclockwise directions. these bacteria modulate their swimming direction towards favorable environments by biasing the direction of flagellar rotation in response to various stimuli. in contrast, rhodobacter sphaeroides expresses a single subpolar flagellum that rotates only cw and responds tactically ... | 2005 | 15716440 |
| [salmonellosis outbreak among first grade schoolchildren, hadera subdistrict]. | this article describes an outbreak of salmonella food-borne infection in a school in or-akiva, hadera sub-district, and analyzes the lessons that can be learned from the episode. | 2005 | 15719813 |
| regulation of enteric endophytic bacterial colonization by plant defenses. | bacterial endophytes reside within the interior of plants without causing disease or forming symbiotic structures. some endophytes, such as klebsiella pneumoniae 342 (kp342), enhance plant growth and nutrition. others, such as salmonella enterica serovar typhimurium (s. typhimurium), are human pathogens that contaminate raw produce. several lines of evidence are presented here to support the hypothesis that plant defense response pathways regulate colonization by endophytic bacteria. an ethylene ... | 2005 | 15720086 |
| antimicrobial susceptibility of animal strains of salmonella enterica isolated in italy from 2001 to 2003. | 2005 | 15720524 | |
| comparison of multidrug resistance gene regions between two geographically unrelated salmonella serotypes. | the aim of this study was to identify chromosomally integrated genes conferring multidrug resistance to a salmonella enterica (s.) serotype typhimurium isolate, phage type dt193, isolated in ireland and to compare them with resistance genes conferring plasmid-mediated multidrug resistance to a s. enteritidis isolate from italy. | 2005 | 15722395 |
| intracellular salmonella inhibit antigen presentation by dendritic cells. | dendritic cells (dc) are important apcs linking innate and adaptive immunity. during analysis of the intracellular activities of salmonella enterica in dc, we observed that viable bacteria suppress ag-dependent t cell proliferation. this effect was dependent on the induction of inducible no synthase by dc and on the function of virulence genes in salmonella pathogenicity island 2 (spi2). intracellular activities of salmonella did not affect the viability, ag uptake, or maturation of dc, but resu ... | 2005 | 15728500 |
| antiamoebic and toxicity studies of a carbamic acid derivative and its therapeutic effect in a hamster model of hepatic amoebiasis. | amoebiasis is an important public health problem in developing countries. entamoeba histolytica, the causative agent of amoebiasis, may develop resistance to nitroimidazoles, a group of drugs considered to be the most effective against this parasitic disease. therefore, research on new drugs for the treatment of this common infection still constitutes an important therapeutic demand. in the present study we determined the effects of a carbamate derivative, ethyl 4-chlorophenylcarbamate (c4), on ... | 2005 | 15728919 |
| integrons and transposons on the salmonella enterica serovar typhimurium virulence plasmid. | a virulence plasmid was identified in a multidrug-resistant salmonella enterica serotype typhimurium strain carrying the spvc, rck, and pefa virulence genes and two class 1 integrons linked to the tn21 and tn1696 transposons. a novel trimethoprim resistance gene, designated dfra23, was also identified within the integron region. the association of multidrug resistance and virulence determinants represents an interesting example of virulence plasmid evolution. | 2005 | 15728925 |
| new integron-associated gene cassette encoding a 3-n-aminoglycoside acetyltransferase. | a fifth gene cassette containing an aacc gene, aacca5, was found in an aacca5-aada7 cassette array in a class 1 integron isolated from a multiply drug resistant salmonella enterica serovar kentucky strain. the aacc-a5 or aac(3)-ie acetyltransferase encoded by aacca5 is related to other aac(3)-i enzymes and confers resistance to gentamicin. | 2005 | 15728939 |
| the fimyz genes regulate salmonella enterica serovar typhimurium invasion in addition to type 1 fimbrial expression and bacterial motility. | an important step in salmonella enterica serovar typhimurium virulence is the ability to invade the intestinal epithelium. the invasion process requires a large number of genes encoded on salmonella pathogenicity island 1 (spi-1) at centisome 63 as well as genes located in other positions throughout the chromosome. expression of the invasive phenotype is tightly regulated by environmental cues that are processed by a complex regulatory scheme. a central player in the invasion regulatory pathway ... | 2005 | 15731035 |
| rapid method for the construction of salmonella enterica serovar typhimurium vaccine carrier strains. | salmonella enterica serovar typhimurium is a versatile organism for the generation of live recombinant vaccines for mucosal immunization. various strategies have been devised for the stable and efficient expression of heterologous antigens by attenuated s. enterica strains, but these methods often require complex manipulations. use of phage lambda red recombinase has recently been devised for gene replacements in escherichia coli and s. enterica after introduction of pcr products. based on this ... | 2005 | 15731059 |
| salmonella enterica serovar typhimurium infection of dendritic cells leads to functionally increased expression of the macrophage-derived chemokine. | gene expression in murine dendritic cells (dcs) infected with green fluorescent protein-expressing salmonella enterica serovar typhimurium brd509 was studied by mrna differential display. infected dcs were sorted from uninfected cells by flow cytometry. the mrna expression patterns of infected and uninfected cells revealed a number of differentially expressed transcripts, which included the macrophage-derived chemokine (mdc). up-regulation of mdc transcription in infected dcs was confirmed by no ... | 2005 | 15731072 |
| sublethal infection of c57bl/6 mice with salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (tlr1), tlr2, and tlr9 mrna as well as a decrease in levels of tlr6 mrna in infected organs. | sublethal infection of c57bl/6 mice with salmonella enterica serovar typhimurium m525p initiates a strong inflammatory response. we measured organ expression of mrna for toll-like receptors and their associated signaling molecules during s. enterica serovar typhimurium infection. during infection, the toll-lie receptor 1 (tlr1), tlr2, and tlr9 mrna levels increased, while tlr6 mrna expression decreased. | 2005 | 15731092 |
| physical linkage of tn3 and part of tn1721 in a tetracycline and ampicillin resistance plasmid from salmonella typhimurium. | the complete nucleotide sequence of the 12 656 bp plasmid pfptb1 from salmonella enterica subsp. enterica serovar typhimurium, which mediates resistance to tetracyclines and ampicillin, was determined. the plasmid was analysed for potential reading frames and structural features indicative of transposons and transposon relics. | 2005 | 15731203 |
| multidrug resistance in salmonella enterica serovar typhi isolated from patients with typhoid fever complications in lagos, nigeria. | the aim of this study was to determine the prevalence of salmonella enterica serovar typhi in patients with pyrexia of unknown origin (puo), and antimicrobial resistance in strains isolated from patients with s. typhi in lagos, nigeria. | 2005 | 15733694 |
| occurrence of multi-resistant salmonella enterica typhimurium dt 104 in austria isolated from humans, animals and food. | 2005 | 15737526 | |
| genetically engineered production of 1-desmethylcobyrinic acid, 1-desmethylcobyrinic acid a,c-diamide, and cobyrinic acid a,c-diamide in escherichia coli implies a role for cbid in c-1 methylation in the anaerobic pathway to cobalamin. | co-expression of the coba gene from propionibacterium freudenreichii and the cbia, -c, -d, -e, -t, -f, -g, -h, -j, -k, -l, and -p genes from salmonella enterica serovar typhimurium in escherichia coli resulted in the production of cobyrinic acid a,c-diamide. a cbid deletion mutant of this strain produced 1-desmethylcobyrinic acid a,c-diamide, indicating that cbid is involved in c-1 methylation in the anaerobic pathway to cobalamin. strains that did not have the cbip gene also produced 1-desmethy ... | 2005 | 15741157 |
| reduction of salmonella enterica serovar enteritidis colonization and invasion by an alfalfa diet during molt in leghorn hens. | the standard method for molting to stimulate multiple egg-laying cycles in laying hens is feed deprivation. however, the physiological changes within hens caused by feed deprivation increase susceptibility of the hens to salmonella enterica serovar enteritidis (se) infection. in an effort to develop an alternative method to induce molting without increasing susceptibility to se, an alfalfa diet was compared with the standard molting method for the level of ovary regression and se colonization. h ... | 2005 | 15742953 |
| percolation of the phd repressor-operator interface. | transcription of the p1 plasmid addiction operon, a prototypical toxin-antitoxin system, is negatively autoregulated by the products of the operon. the phd repressor-antitoxin protein binds to 8-bp palindromic phd-binding sites in the promoter region and thereby represses transcription. the toxin, doc, mediates cooperative interactions between adjacent phd-binding sites and thereby enhances repression. here, we describe a homologous operon from salmonella enterica serovar typhimurium which has t ... | 2005 | 15743936 |
| nucleotide sequence of the head assembly gene cluster of bacteriophage l and decoration protein characterization. | the temperate salmonella enterica bacteriophage l is a close relative of the very well studied bacteriophage p22. in this study we show that the l procapsid assembly and dna packaging genes, which encode terminase, portal, scaffold, and coat proteins, are extremely close relatives of the homologous p22 genes (96.3 to 99.1% identity in encoded amino acid sequence). however, we also identify an l gene, dec, which is not present in the p22 genome and which encodes a protein (dec) that is present on ... | 2005 | 15743953 |
| cyclic amp (camp) and camp receptor protein influence both synthesis and uptake of extracellular autoinducer 2 in escherichia coli. | bacterial autoinducer 2 (ai-2) is proposed to be an interspecies mediator of cell-cell communication that enables cells to operate at the multicellular level. many environmental stimuli have been shown to affect the extracellular ai-2 levels, carbon sources being among the most important. in this report, we show that both ai-2 synthesis and uptake in escherichia coli are subject to catabolite repression through the cyclic amp (camp)-crp complex, which directly stimulates transcription of the lsr ... | 2005 | 15743955 |
| temperature sensitive mutation in the 38 kda minor structural protein gene of phage mb78 interferes with phage morphogenesis. | temperature sensitive mutation in the gene for the 38 kda minor structural protein of the phage mb78, a virulent phage of salmonella enterica serovar typhimurium, interferes with phage development at restrictive temperature. electron microscopy of particles produced at non-permissive temperature indicated that the particles formed are tailless. two types of particles are seen: (i) empty capsids, which are not perfect icosahedral (ii) icosahedral particles filled with dna. the gene for the 38 kda ... | 2005 | 15744577 |
| effect of heat, acidification, and chlorination on salmonella enterica serovar typhimurium cells in a biofilm formed at the air-liquid interface. | bacterial biofilms have great significance for public health, since biofilm-associated microorganisms exhibit dramatically decreased susceptibility to antimicrobial agents and treatments. to date most attention has focused on biofilms that arise from the colonization of solid-liquid or solid-air interfaces. it is of interest that colonization of the interface between air and liquid, which can be selectively advantageous for aerobic or facultative aerobic bacteria, has been rarely studied, althou ... | 2005 | 15746314 |
| acquisition of resistance to extended-spectrum cephalosporins by salmonella enterica subsp. enterica serovar newport and escherichia coli in the turkey poult intestinal tract. | salmonella enterica subsp. enterica serovar newport resistant to the extended-spectrum cephalosporins (escs) and other antimicrobials causes septicemic salmonellosis in humans and animals and is increasingly isolated from humans, animals, foods, and environmental sources. mechanisms whereby serovar newport bacteria become resistant to escs and other classes of antimicrobials while inhabiting the intestinal tract are not well understood. the present study shows that 25.3% of serovar newport strai ... | 2005 | 15746317 |
| enhanced survival of salmonella enterica in vesicles released by a soilborne tetrahymena species. | nondestructive ingestion by soilborne protozoa may enhance the environmental resiliency of important bacterial pathogens and may model how such bacteria evade destruction in human macrophages. here, the interaction of salmonella enterica serovar thompson with a soilborne tetrahymena sp. isolate was examined using serovar thompson cells labeled with the green fluorescent protein. the bacteria were mixed in solution with cells of tetrahymena at several ratios. during incubation with serovar thomps ... | 2005 | 15746361 |
| genomic comparisons of salmonella enterica serovar dublin, agona, and typhimurium strains recently isolated from milk filters and bovine samples from ireland, using a salmonella microarray. | salmonella-induced enterocolitis is the leading food-borne illness with a lethal outcome and causes millions of cases of gastroenteritis each year. we examined genomic variation among 12 environmental, veterinary, and clinical salmonella enterica serovar dublin, agona, and typhimurium strains isolated in ireland between 2000 and 2003, as well as two clinical isolates from canada and four archival isolates, which belonged to serovars dublin and agona. using dna-dna hybridization to a microarray c ... | 2005 | 15746367 |
| host susceptibility and clinical outcomes in toll-like receptor 5-deficient patients with typhoid fever in vietnam. | toll-like receptor 5 (tlr5) mediates innate immune responses to bacterial pathogens by binding to flagellin. a polymorphism in the tlr5 gene introduces a premature stop codon (tlr5(392stop)) that is associated with susceptibility to legionnaires disease. here we investigated whether tlr5(392stop) was associated with typhoid fever. the frequency of tlr5(392stop) was not significantly different in 565 patients with typhoid fever and 281 ethnically matched control subjects. furthermore, tlr5 defici ... | 2005 | 15747241 |
| adhesion of bacteria to resected human colonic tissue: quantitative analysis of bacterial adhesion and viability. | adhesion to the intestinal mucosa is considered to be one of the main selection criteria of lactic acid bacteria for probiotic use. adhesive probiotics are, for example, considered to provide better antagonism against pathogenic bacteria when compared to non-adhesive strains. here a new model is described for studying adhesion and interaction of probiotic and pathogenic bacteria in the intestinal mucus in which the intestinal microbiota is present. the model is based on the use of human intestin ... | 2005 | 15748990 |
| nosocomial outbreak caused by salmonella enterica serotype livingstone producing ctx-m-27 extended-spectrum beta-lactamase in a neonatal unit in sousse, tunisia. | in this study, we report an outbreak of salmonella enterica serotype livingstone resistant to extended-spectrum cephalosporins that occurred in a neonatal ward of the maternity department of farhat hached hospital, sousse, tunisia, in 2002. a total of 16 isolates were recovered from 16 babies hospitalized in the ward during the period 1 to 16 july. all these babies developed diarrhea, and three of them developed septicemia. all the isolates demonstrated resistance to ceftriaxone and ceftazidime ... | 2005 | 15750057 |
| vi antigen expression in salmonella enterica serovar typhi clinical isolates from pakistan. | the accurate identification of salmonella enterica subsp. enterica serovar typhi variants that fail to express the capsular polysaccharide, vi, is an important and much discussed issue for medical microbiology. we have tested a multiplex pcr method which shows the presence or absence of the genetic locus required for vi expression. of 2,222 salmonella serovar typhi clinical isolates collected from patients' blood over a 4-year period in a region of pakistan where typhoid is endemic, 12 tested ne ... | 2005 | 15750077 |
| analysis of salmonella enterica serotype typhi pulsed-field gel electrophoresis patterns associated with international travel. | typhoid fever is a significant cause of morbidity and mortality worldwide, causing an estimated 16 million cases and 600,000 deaths annually. although overall rates of the disease have dramatically decreased in the united states, the number of travel-related infections has increased in recent decades. drug resistance among salmonella enterica serotype typhi strains has emerged worldwide, making antimicrobial susceptibility testing an important function in public health laboratories. pulsed-field ... | 2005 | 15750084 |
| typhoid fever associated with acute appendicitis caused by an h1-j strain of salmonella enterica serotype typhi. | while most strains of salmonella enterica serotype typhi, the etiologic agent of typhoid fever, have only a phase 1 flagellar antigen, h1-d, variations of the flagellar antigen have been observed. although h1-j strains (one of the flagellar antigen variants) account for 10 to 50% of s. enterica serotype typhi strains found in indonesia, there have been no published data to suggest its existence in other parts of the world. we describe a case of typhoid fever associated with acute appendicitis ca ... | 2005 | 15750137 |
| synthesis and evaluation of mimetics of udp and udp-alpha-d-galactose, dtdp and dtdp-alpha-d-glucose with monosaccharides replacing the key pyrophosphate unit. | a series of 5'-o-glycosyl-uridine and thymidine derivatives have been prepared as potential mimics of sugar nucleotides and nucleotide-diphosphates. these compounds proved not to be inhibitors of bovine beta-1,4-galactosyltransferase although some showed moderate inhibition of salmonella dtdp-alpha-d-glucose 4,6-dehydratase (rmlb). | 2005 | 15750655 |
| ligand binding properties of bacterial hemoglobins and flavohemoglobins. | bacterial hemoglobins and flavohemoglobins share a common globin fold but differ otherwise in structural and functional aspects. the bases of these differences were investigated through kinetic studies on oxygen, carbon monoxide, and nitric oxide binding. the novel bacterial hemoglobins from clostridium perfringens and campylobacter jejuni and the flavohemoglobins from bacillus subtilis and salmonella enterica serovar typhi have been analyzed. examination of the biochemical and ligand binding pr ... | 2005 | 15751990 |
| the salmonella genomic island 1 is an integrative mobilizable element. | salmonella genomic island 1 (sgi1) is a genomic island containing an antibiotic resistance gene cluster identified in several salmonella enterica serovars. the sgi1 antibiotic resistance gene cluster, which is a complex class 1 integron, confers the common multidrug resistance phenotype of epidemic s. enterica typhimurium dt104. the sgi1 occurrence in s. enterica serovars typhimurium, agona, paratyphi b, albany, meleagridis and newport indicates the horizontal transfer potential of sgi1. here, w ... | 2005 | 15752209 |
| chitosan inactivates spoilage yeasts but enhances survival of escherichia coli o157:h7 in apple juice. | to develop new measures for controlling both spoilage and pathogenic micro-organisms in unpasteurized apple juice using chitosan. | 2005 | 15752333 |
| effect of regulation and education on reptile-associated salmonellosis. | reptiles have become increasingly common as domestic pets, and with them reptile-associated salmonella infections in humans. from 1990 to 2000, a total of 339 reptile-associated salmonella cases were reported in sweden. in 1996, as part of its efforts to adapt its import regulations to those of the european union, sweden no longer required certificates stating that imported animals were free of salmonella. a subsequent increase was noted in the incidence of reptile-associated cases from 0.15/100 ... | 2005 | 15757554 |
| genome update: base skews in 200+ bacterial chromosomes. | 2005 | 15758208 | |
| identification of the outer-membrane protein pagc required for the serum resistance phenotype in salmonella enterica serovar choleraesuis. | serum resistance is a crucial virulence factor for the development of systemic infections, including bacteraemia, by many pathogenic bacteria. salmonella enterica serovar choleraesuis is an important enteric pathogen that causes serious systemic infections in swine and humans. here, it was found that, when introduced into escherichia coli, a recombinant plasmid carrying the pagc gene from a plasmid-based genomic library of s. enterica serovar choleraesuis conferred a high-level resistance to the ... | 2005 | 15758232 |
| antiprotease inactivation by salmonella enterica released from infected macrophages. | the mammalian serine protease plasmin, which has an important role in extracellular matrix degradation during cell migration, is regulated by the plasma antiprotease alpha(2)-antiplasmin (alpha(2)ap). the surface protease pgte of salmonella enterica serovar typhimurium proteolytically inactivated alpha(2)ap. pgte also activates the plasma zymogen plasminogen to plasmin, and bacteria expressing pgte promoted degradation of extracellular matrix laminin in the presence of plasminogen and alpha(2)ap ... | 2005 | 15760453 |
| class 1 integron-associated gene cassettes in salmonella enterica subsp. enterica serovar agona isolated from pig carcasses in brazil. | two multiresistant salmonella enterica subsp. enterica serovar agona isolates from pig carcasses were investigated for antimicrobial resistance genes and their location with particular reference to the detection of class 1 integrons. | 2005 | 15761062 |
| salmonella invasion gene regulation: a story of environmental awareness. | salmonella enterica serovar typhimurium causes human gastroenteritis and a systemic typhoid-like infection in mice. a critical virulence determinant of salmonella is the ability to invade mammalian cells. the expression of genes required for invasion is tightly regulated by environmental conditions and a variety of regulatory genes. the hila regulator encodes an ompr/toxr family transcriptional regulator that activates the expression of invasion genes in response to both environmental and geneti ... | 2005 | 15765064 |
| rapid phenotypic characterization of salmonella enterica strains by pyrolysis metastable atom bombardment mass spectrometry with multivariate statistical and artificial neural network pattern recognition. | pyrolysis mass spectrometry was investigated for rapid characterization of bacteria. spectra of salmonella were compared to their serovars, pulsed-field gel electrophoresis (pfge) patterns, antibiotic resistance profiles, and mic values. pyrolysis mass spectra generated via metastable atom bombardment were analyzed by multivariate principal component-discriminant analysis and artificial neural networks (anns). spectral patterns developed by discriminant analysis and tested with leave-one-out (lo ... | 2005 | 15767008 |
| interaction of salmonella enterica subspecies enterica serovar typhimurium and mung bean (phaseolus aureus) plants. | the effect of salmonella enterica subspecies enterica serovar typhimurium, a zoonotic serovar, on mung bean (phaseolus aureus) cultivar pant mung-3 plants was studied. inoculation of mung bean seeds with salmonella typhimurium (7.2 x 10(5) cfu/ml) reduced sprouting rate (p < 0.07). this effect was more pronounced at higher levels of contamination. in the soil inoculated with salmonella typhimurium (7.2 x 10(6) cfu/g), germination was retarded and the number of defective sprouts was also signific ... | 2005 | 15771169 |
| combination of immunomagnetic separation with real-time pcr for rapid detection of salmonella in milk, ground beef, and alfalfa sprouts. | a rapid, specific, and sensitive method for detecting salmonella spp. in pasteurized milk, ground beef, and alfalfa sprouts was developed. the method combined immunomagnetic separation with a real-time pcr assay based on the double-stranded dna binding dye sybr green i. the primers used produced a product with a melting temperature of 87+/-0.5 degrees c during the pcr assay by amplifying a 284-bp sequence from the invasive gene (inva) of salmonella. the method was successful in detecting 20 salm ... | 2005 | 15771182 |
| antimicrobial resistance patterns and serotype distribution among salmonella enterica strains in turkey, 2000-2002. | since turkey currently lacks a national reference center for salmonella infections, the present study was conducted to document the distribution of serotypes and antimicrobial resistance patterns among salmonella enterica isolates recovered from clinical samples in ten turkish provinces over a 2-year period. among the 620 salmonella enterica isolates recovered between 1 july 2000 and 30 june 2002, strains belonging to the serotypes enteritidis (47.7%), typhimurium (34.7%), paratyphi b (6.0%), ty ... | 2005 | 15772822 |
| [infective etiology of diarrhea in adults with hiv infection in dakar: a case-control study on 594 patients]. | a survey was conducted in dakar, senegal from may 1997 to may 1999, to identify major types and prevalences of bacteria, parasites, fungi and rotaviruses associated with diarrhea in relation to human immunodeficiency virus serostatus with the aim to provide guidance to physicians for case management. etiologic agents were identified in a case-control study: cases were hiv-infected patients with diarrhea (hiv+ d+) and hiv seronegative patients with diarrhea (hiv- d+); controls were hiv-infected p ... | 2001 | 15773157 |
| monitoring age-related susceptibility of young mice to oral salmonella enterica serovar typhimurium infection using an in vivo murine model. | neonates and young children are acutely susceptible to infections by gastrointestinal bacterial pathogens, such as salmonella enterica serovar typhimurium (s. typhimurium). to reveal age-related differences in susceptibility to this pathogen, we used in vivo bioluminescence imaging (bli) to monitor the progression of infection in neonatal (1-wk-old), suckling (2-wk-old), juvenile (4-wk-old), and adult (6-wk-old) balb/c mice. mice were orally infected with various doses of a bioluminescent-labele ... | 2005 | 15774831 |
| inhibition of salmonella enterica serovar typhimurium lipopolysaccharide deacylation by aminoarabinose membrane modification. | salmonella enterica serovar typhimurium remodels the lipid a component of lipopolysaccharide, a major component of the outer membrane, to survive within animals. the activation of the sensor kinase phoq in host environments increases the synthesis of enzymes that deacylate, palmitoylate, hydroxylate, and attach aminoarabinose to lipid a, also known as endotoxin. these modifications promote bacterial resistance to antimicrobial peptides and reduce the host recognition of lipid a by toll-like rece ... | 2005 | 15774888 |
| analysis of the hypervariable region of the salmonella enterica genome associated with trna(leux). | the divergence of salmonella enterica and escherichia coli is estimated to have occurred approximately 140 million years ago. despite this evolutionary distance, the genomes of these two species still share extensive synteny and homology. however, there are significant differences between the two species in terms of genes putatively acquired via various horizontal transfer events. here we report on the composition and distribution across the salmonella genus of a chromosomal region designated sp ... | 2005 | 15774890 |
| evaluation of an intracellular-activated promoter for the generation of live salmonella recombinant vaccines. | salmonella enterica serovar typhimurium is a versatile host organism for the generation of recombinant live vaccines for mucosal immunization. we investigated the performance of an intracellular-activated promoter for expression of heterologous antigens by salmonella carrier strains. we observed that intracellular expressed antigens were more efficient in elicitation of humoral and cellular immune responses than constitutively expressed antigens. furthermore, the intracellular-activated promoter ... | 2005 | 15780440 |
| the genome sequence of salmonella enterica serovar choleraesuis, a highly invasive and resistant zoonotic pathogen. | salmonella enterica serovar choleraesuis (s. choleraesuis), a highly invasive serovar among non-typhoidal salmonella, usually causes sepsis or extra-intestinal focal infections in humans. s. choleraesuis infections have now become particularly difficult to treat because of the emergence of resistance to multiple antimicrobial agents. the 4.7 mb genome sequence of a multidrug-resistant s. choleraesuis strain sc-b67 was determined. genome wide comparison of three sequenced salmonella genomes revea ... | 2005 | 15781495 |
| protective efficacy of maternal antibodies induced by salmonella toxoid (vaccine). | an attempt was made to evaluate the protective efficacy of maternal antibodies in chicks against salmonellosis. layer chicks ageing 21 days were individually vaccinated with 100 microg of salmonella enterica subspecies enterica serovar weltevreden (bm 1643) toxoid adjuvanted with vitamin e subcutaneously. after 90 days of the primary vaccination the birds were given booster dose of the vaccine. the saline extract of the yolk of eggs laid by the vaccinated birds yielded agglutination and elisa ti ... | 2005 | 15782817 |
| purification and characterization of rihc, a xanthosine-inosine-uridine-adenosine-preferring hydrolase from salmonella enterica serovar typhimurium. | salmonella enterica serovar typhimurium normally salvage nucleobases and nucleosides by the action of nucleoside phosphorylases and phosphoribosyltransferases. in contrast to escherichia coli, which catabolizes xanthosine by xanthosine phosphorylase (xapa), salmonella cannot grow on xanthosine as the sole carbon and energy source. by functional complementation, we have isolated a nucleoside hydrolase (rihc) that can complement a xapa deletion in e. coli and we have overexpressed, purified and ch ... | 2005 | 15784179 |
| salmonella enterica serovar typhi with decreased susceptibility to ciprofloxacin--an emerging problem in bangladesh. | 2005 | 15784317 | |
| cloning and sequencing of a genomic island found in the brazilian purpuric fever clone of haemophilus influenzae biogroup aegyptius. | a genomic island was identified in the haemophilus influenzae biogroup aegyptius brazilian purpuric fever (bpf) strain f3031. this island, which was also found in other bpf isolates, could not be detected in non-bpf biogroup aegyptius strains or in nontypeable or typeable h. influenzae strains, with the exception of a region present in the type b eagan strain. this 34,378-bp island is inserted, in reference to h. influenzae rd kw20, within a choline transport gene and contains a mosaic structure ... | 2005 | 15784532 |
| antibiotic-free plasmid stabilization by operator-repressor titration for vaccine delivery by using live salmonella enterica serovar typhimurium. | live, attenuated bacteria are effective vectors for heterologous antigen delivery. however, loss of heterologous gene-bearing plasmids is problematic, and antibiotics and their resistance genes are not desirable for in vivo dna vaccine delivery due to biosafety and regulatory concerns. to solve this problem, we engineered the first vaccine delivery strain that has no requirement for antibiotics or other selectable marker genes to maintain the recombinant plasmid. this model strain of salmonella ... | 2005 | 15784541 |
| mouse paneth cell secretory responses to cell surface glycolipids of virulent and attenuated pathogenic bacteria. | mouse paneth cells respond to bacteria and bacterial cell surface antigens by discharging secretory granules into the lumen of small intestinal crypts (t. ayabe et al., nat. immunol. 1:113-118, 2000). to investigate mechanisms regulating these responses, purified surface glycolipid molecules with known acyl chain modifications and attenuated properties were tested for the ability to stimulate paneth cell secretion. the antigens included lipopolysaccharide (lps) from wild-type and msbb-null esche ... | 2005 | 15784576 |
| identification and functional characterization of chicken toll-like receptor 5 reveals a fundamental role in the biology of infection with salmonella enterica serovar typhimurium. | toll-like receptors (tlrs) are a major component of the pattern recognition receptor repertoire that detect invading microorganisms and direct the vertebrate immune system to eliminate infection. in chickens, the differential biology of salmonella serovars (systemic versus gut-restricted localization) correlates with the presence or absence of flagella, a known tlr5 agonist. chicken tlr5 (chtlr5) exhibits conserved sequence and structural similarity with mammalian tlr5 and is expressed in tissue ... | 2005 | 15784580 |
| multiple antimicrobial resistant salmonella enterica serovar paratyphi b variant java in cattle: a case report. | an epidemiological investigation of a calf rearing premises and a closely associated dairy herd was carried out after the isolation of salmonella enterica serovar paratyphi b variant java phage type 3b variant 2 from clinically diseased calves on the premises. the isolate was resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides, tetracyclines, trimethoprim and cefoperazone. the organism was widespread on the calf unit and was also recovered from the dairy premises, mainly from g ... | 2005 | 15789647 |
| molecular epidemiology of salmonella enterica serovar enteritidis strains by pulsed-field gel electrophoresis isolated in the slovak republic. | a total 44 isolates of s. enterica serovar enteritidis (s. enteritidis) belonged to three different phage types (pts) 9a, 13a, 25 were analyzed by the technique of pulsed-field gel electrophoresis (pfge). thirty and three strains were from two outbreaks (central and southern regions of the slovak republic pts 13a, 25) and 11 isolates were sporadic isolates (pt9a). these isolates showed two different patterns in pfge with xbai digestion. strains of pt13a generated pfp a and isolates of pt25 showe ... | 2004 | 15790080 |
| hierarchical gene regulators adapt salmonella enterica to its host milieus. | the facultative intracellular pathogen salmonella enterica serovar typhimurium possesses an elaborate set of virulence genes that enables the bacterium successfully to move between and adapt to the environment, different host organisms and various micro-niches within a given host. expression of virulence attributes is by no means constitutive. rather, the regulation of virulence determinants is highly coordinated and integrated into normal bacterial physiological responses. by integrating discri ... | 2005 | 15790293 |
| the role of host cell death in salmonella infections. | salmonella enterica is an important enteric pathogen of humans and a variety of domestic and wild animals. infection is initiated in the intestinal tract, and severe disease produces widespread destruction of the intestinal mucosa. salmonella strains can also disseminate from the intestine and produce serious, sometimes fatal infections with considerable cytopathology in a number of systemic organs. a combination of bacterial genetic and cell biology studies have shown that salmonella uses speci ... | 2005 | 15791954 |
| role of salmonella surface components in immunomodulation of inflammatory mediators. | salmonella enterica serovar typhimurium and its surface components were assessed for their inflammatory potential by footpad oedema test using plethysmometer. inflammation was found to be the highest when outer membrane proteins (omps) were used as inflammagen followed by lipid associated protein-lipopolysaccharide complex (lap-lps) and lipopolysaccharides (lps). inflammation produced by omps was found to be comparable to that by carrageenan (a known positive inflammagen). however, injection of ... | 2005 | 15792366 |
| bla(ctx-m) genes in clinical salmonella isolates recovered from humans in england and wales from 1992 to 2003. | cefotaximases (ctx-m) are a rapidly growing class a beta-lactamase family that has been found among a wide range of clinical bacteria. one hundred and six isolates were selected from 278,308 salmonella isolates based on resistance to ampicillin and cephalosporins and subjected to further characterization. fourteen isolates were bla(ctx-m) pcr positive, and cefotaxime mics for these isolates were > or = 16 mg/liter. furthermore, sequence analysis revealed the presence of type ctx-m9, -15, or -17 ... | 2005 | 15793104 |
| bactericidal and antiendotoxic properties of short cationic peptides derived from a snake venom lys49 phospholipase a2. | the activities of short synthetic, nonhemolytic peptides derived from the c-terminal region of myotoxin ii, a catalytically inactive phospholipase a2 homologue present in the venom of the snake bothrops asper, have been shown to reproduce the bactericidal activity of the parent protein. they combine cationic and hydrophobic-aromatic amino acids, thus functionally resembling the antimicrobial peptides of innate defenses. this study evaluated the antimicrobial and antiendotoxic properties of a 13- ... | 2005 | 15793109 |
| rollback of salmonella enterica serotype typhi resistance to chloramphenicol and other antimicrobials in kolkata, india. | 2005 | 15793167 | |
| [outbreak of salmonella enteriditis food poisoning at a dining hall facility]. | an outbreak of salmonella enteriditis food poisoning having occurred at two banquet halls, affecting eight groups of guests, is described. this research was aimed at determining the food by means of which this illness was transmitted. | 2005 | 15794585 |
| an attenuated salmonella enteritidis strain derivative of the main genotype circulating in uruguay is an effective vaccine for chickens. | we have recently reported that salmonella enterica serovar enteritidis (s. enteritidis) strains circulating in uruguay, are unevenly distributed among different genetic subtypes, with a predominant genotype that is a common contaminant of poultry-derived food and that accounts for the vast majority of human cases of food-borne disease. herein, we describe the construction of a genetically-defined aroc derivative (lvr02) of a local strain of s. enteritidis belonging to the major genetic type. we ... | 2005 | 15795080 |
| comparison of fecal culture and danish mix-elisa for determination of salmonella enterica subsp. enterica prevalence in growing swine. | in the usa, control of food-borne salmonellosis associated with meat consumption has been predominantly focused at slaughter and processing. it is expected that standards at slaughter and processing will become more stringent, creating pressure to reduce prevalence of salmonella-positive food animals through on-farm interventions. the aim of this study was to compare traditional fecal culture and the danish mix-elisa (dme) for determination of salmonella prevalence pre-harvest in swine. in trial ... | 2005 | 15795083 |
| dietary fructooligosaccharides increase intestinal permeability in rats. | we showed previously that fructooligosaccharides (fos) decrease the resistance to salmonella infection in rats. however, the mechanism responsible for this effect is unclear. therefore, we examined whether dietary fos affects intestinal permeability before and after infection with salmonella enterica serovar enteritidis. male wistar rats were fed restricted quantities of a purified diet that mimicked the composition of a western human diet. the diet was supplemented with 60 g/kg cellulose (contr ... | 2005 | 15795444 |
| dna methylation modulates salmonella enterica serovar typhimurium virulence in caenorhabditis elegans. | salmonella enterica serovar typhimurium was previously shown to be virulent in caenorhabditis elegans. here we demonstrate that dna adenine methyltransferase (dam) modulates salmonella virulence in the nematode, as it does in mice. after 5 days of continual exposure to bacteria, twice as many worms died when exposed to the wild-type than the dam-mutant strain of salmonella. similar trends in virulence were observed when worms were exposed to salmonella strains for 5 h and transferred to the avir ... | 2005 | 15796979 |
| slya regulates the collagenase-mediated cytopathic phenotype in multiresistant salmonella. | salmonella enterica serotype typhimurium phagetype dt104 (dt104) is a foodborne pathogen with a multiresistant phenotype conferred by a genomic-based integron structure designated as sgi1. recently, a novel cytopathic phenotype was ascribed to several isolates of dt104 recovered from veal calves. this phenotype is dependent upon clg, a gene encoding a collagenase in salmonella. using a novel transposon system and an rt-pcr assay for detection of clg expression, we identified slya as a regulator ... | 2005 | 15797813 |
| diversity of genome structure in salmonella enterica serovar typhi populations. | the genomes of most strains of salmonella and escherichia coli are highly conserved. in contrast, all 136 wild-type strains of salmonella enterica serovar typhi analyzed by partial digestion with i-ceui (an endonuclease which cuts within the rrn operons) and pulsed-field gel electrophoresis and by pcr have rearrangements due to homologous recombination between the rrn operons leading to inversions and translocations. recombination between rrn operons in culture is known to be equally frequent in ... | 2005 | 15805510 |
| regulation of nad synthesis by the trifunctional nadr protein of salmonella enterica. | the three activities of nadr were demonstrated in purified protein and assigned to separate domains by missense mutations. the n-terminal domain represses transcription of genes for nad synthesis and salvage. the c-terminal domain has nicotinamide ribose kinase (nmr-k; ec 2.7.1.22) activity, which is essential for assimilation of nmr, converting it internally to nicotinamide mononucleotide (nmn). the central domain has a weak adenylyltransferase (nmn-at; ec 2.7.7.1) activity that converts nmn di ... | 2005 | 15805524 |
| catabolite repression of the propionate catabolic genes in escherichia coli and salmonella enterica: evidence for involvement of the cyclic amp receptor protein. | previous studies with salmonella enterica serovar typhimurium lt2 demonstrated that transcriptional activation of the prpbcde operon requires the function of transcription factor prpr, sigma-54, and ihf. in this study, we found that transcription from the prpbcde and prpr promoters was down-regulated by the addition of glucose or glycerol, indicating that these genes may be regulated by the cyclic amp (camp)-camp receptor protein (crp) complex. targeted mutagenesis of a putative crp-binding site ... | 2005 | 15805526 |
| biotinylation facilitates the uptake of large peptides by escherichia coli and other gram-negative bacteria. | gram-negative bacteria such as escherichia coli can normally only take up small peptides less than 650 da, or five to six amino acids, in size. we have found that biotinylated peptides up to 31 amino acids in length can be taken up by e. coli and that uptake is dependent on the biotin transporter. uptake could be competitively inhibited by free biotin or avidin and blocked by the protonophore carbonyl m-chlorophenylhydrazone and was abolished in e. coli mutants that lacked the biotin transporter ... | 2005 | 15812011 |
| co-regulation of salmonella enterica genes required for virulence and resistance to antimicrobial peptides by slya and phop/phoq. | analysis of the transcriptome of slya mutant salmonella enterica serovar typhimurium revealed that many slya-dependent genes, including pagc, pagd, ugtl, mig-14, virk, phon, pgte, pipb2, sopd2, pagj and pagk, are also controlled by the phop/phoq regulatory system. many slya- and phop/phoq-co-regulated genes have functions associated with the bacterial envelope, and some have been directly implicated in virulence and resistance to antimicrobial peptides. purified his-tagged slya binds to the pagc ... | 2005 | 15813739 |
| tolc but not acrb is essential for multidrug-resistant salmonella enterica serotype typhimurium colonization of chicks. | to study the role of the multidrug efflux system acrab-tolc in resistance of multidrug-resistant salmonella enterica serotype typhimurium (s. typhimurium) phage type dt104 and dt204 strains to detergents and bile salts. to evaluate the importance of the inner membrane transporter acrb and the outer membrane component tolc of this efflux system in the colonization of two multidrug-resistant s. typhimurium dt104 and one dt204 strain in chicks. | 2005 | 15814604 |
| discrimination within phenotypically closely related definitive types of salmonella enterica serovar typhimurium by the multiple amplification of phage locus typing technique. | multilocus sequence typing (mlst) is a relatively new high-resolution typing system employed for epidemiological studies of bacteria, including salmonella. discrimination based on mlst of housekeeping genes may be problematical, due to the high identity of gene sequences of closely related salmonella species. the presence of genomic sequences derived from stable temperate phages in salmonella offers an alternative for mlst of salmonella. we have used mlst of prophage loci in salmonella enterica ... | 2005 | 15814973 |
| an outbreak of multidrug-resistant salmonella enterica serotype newport infections linked to the consumption of imported horse meat in france. | in 2003, 14 cases of multidrug-resistant salmonella newport infections were reported. this is the first documented foodborne outbreak of multidrug-resistant s. newport in france. the blacmy gene was present in all isolates. all cases reported having eaten horse meat from a common wholesaler. the country of origin of the imported meat could not be identified. | 2005 | 15816165 |
| bacterial flagellar diversity in the post-genomic era. | flagellar biosynthesis has been studied most thoroughly in laboratory strains of escherichia coli and salmonella enterica. however, genome sequencing has uncovered flagellar loci in distantly related bacteria. we have used homology searches to determine how far the e. coli/s. enterica paradigm can be generalised to other flagellar systems. numerous previously unrecognized homologues of flagellar components were discovered, including novel flgm, flgn, flik and flio homologues. homology was found ... | 2005 | 15817382 |
| prpz, a salmonella enterica serovar typhi serine/threonine protein phosphatase 2c with dual substrate specificity. | genes encoding eukaryotic-type protein kinases and phosphatases are present in many bacterial genomes. an orf encoding a polypeptide with homology to protein phosphatases 2c (pp2cs) was identified in the genomes of salmonella enterica serovar typhi strains ct18 and ty2. this protein, termed prpz, is the first pp2c to be identified in enterobacteria. analysis of the amino acid sequence revealed two distinct domains: the n-terminal segment containing motifs of the catalytic domain of pp2cs and the ... | 2005 | 15817783 |