Publications

cyclic nucleotide-dependent protein kinase activity in malignant and cyclic amp-induced "differentiated" neuroblastoma cells in culture.		1996	178300
distribution of phosphatidylinositol biosynthetic activities among cell fractions from rat liver.		1976	178302
effect of isoproterenol and acetylcholine treatment in vitro on cyclic nucleotides in mouse sex accessory organs.		1976	178321
ovarian tumours in childhood: a 27-year review.	twenty-five children treated for ovarian neoplasms at the royal hospital for sick children, yorkhill,glasgow, between 1947 and 1974 are reported. eight of the patients had malignant tumours and 17 benign. the patients with benign tumours were treated by either salpingo-oophorectomy or oophorectomy. the malignant cases were treated with either surgery alone or in combination with deep x-ray therapy and/or chemotherapy. two patients died of malignant teratoma, but the remaining 6 with malignant te ...	1996	178398
[traumatic deciduoma and delayed nidation in castrated pregnant rat after acth injection].	after administration of acth it is possible to obtain traumatic deciduomata in rats ovariectomized during early pregnancy and delayed implantation in rats ovariectomized day 4 of pregnancy and injected dayly with oestradiol from day 8 or 9. the substance responsible seems to be progesterone or progesterone like corticoid.	1975	178414
investigations on isolated islets of langerhans in vitro. xiii. experiments concerning the preparation conditions with collagenase.	during the digestion of pancreatic pieces with collagenase for prepartion of isolated islets the enzymes in incubation medium (collangenolytic and/or proteolytic) can alter the secretion behavior of a- and b-cells. insulin release after such an enzymatic attack is characterized by an enhanced basal secretion and a diminished and delayed glucose response. overdigestion results in a decreased glucagon secretion in response to arginine, a diminished insulin content, and a decreased thiol-protein-di ...	1976	178501
clay-organic complexes and interaction: aromatic molecules.		1996	178503
studies on the stimulation of camp metabolism in human lymphocytes by latex polymers.		1976	178514
tissue specific differences in the 2'-o-methylation of eukaryotic 5.8s ribosomal rna.		1975	178541
the process of formation of the 5' -terminal modified structure in messenger rna of cytoplasmic polyhedrosis virus.		1976	178543
comparison of guinea pig cytomegalovirus and guinea pig herpes-like virus: pathogenesis and persistence in experimentally infected animals.	the pathogenesis of guinea pig cytomegalovirus (gpcmv) and guinea pig herpes-like virus (gphlv) in guinea pigs was compared. animals were inoculated with the two viruses by different routes and sacrificed after varying periods of time. gpcmv was consistently isolated from salivary gland 2 weeks postinoculation and thereafter following intraperitoneal or subcutaneous incoulaton. virus was less frequently found in other tissues including blood, spleen, and kidney. intranuclear inclusions were seen ...	1976	178599
an adrenergic mechanism for visual neuroregulation.	studies of the diffuse electroretinogram (erg) and evoked reponses in the optic lobe in the baby chick have shown that epinephrine produces changes in both. epinephrine produces enhancement of the a-wave and depression of the b- and d-waves in both intact and isolated eyes. in the optic lobe it produces enhancement of both components of the evoked response. the presence of epinephrine in the vertebrate retina and the optic lobe of chicks suggests that these changes may reflect the involvement of ...	1975	178882
analysis of cytomegalovirus genomes with restriction endonucleases hin d iii and ecor-1.	cleavage of genomes of eleven human, one simian, and one simian-related cytomegalovirus (cmv) isolate by the restriction endonucleases hind iii and ecor-1 generated reproducible dna fragments. the size range of cmv dna fragments as estimated by contour length measurements in comparison with simian virus 40 form ii dna and by coelectrophoresis with ecor-1 fragments of herpes simplex virus dna varied between 15 x 10(6) and 0.5 x 10(6) daltons. comparison of the cleavage products of each isolate in ...	1976	178916
criteria for producing high quality animals for research.	the criteria for the breeding or purchase of high quality research animals in general, and of dogs, cats, monkeys, rats, mice, guinea pigs, and rabbits were discussed. the reasons for using high quality animals are: economic, accuracy and reproducibility of results, no effects due to the presence of pathogens, and reduction of human health hazards.	1976	178960
radioimmunoassay of 17beta-hydroxy-5alpha-androstan-3-one, 4-androstene-3,17-dione, dehydroepiandrosterone, 17-hydroxyprogesterone and progesterone and its application to the human male plasma.		1976	178963
[abdominal neoplasms in children].		1997	179051
recurrent intussusception due to a primary colloid carcinoma of the large bowel in a child.		1997	179075
neural properties of cultured human endocrine tumor cells of proposed neural crest origin.	cells from human endocrine tumors of proposed neural crest origin--five pheochromocytomas, two medullary carcinomas of the thyroid, and two bronchial carcinoids--were grown in monolayer culture. cells from all nine tumors, including epithelial forms of medullary carcinoma of the thyroid and bronchial carcinoid cells, and epithelial and neuron-like pheochromocytoma cells demonstrated all-or-nothing, short-duration action potentials.	1976	179139
[intrapulmonary fibromas (author's transl)].	based on 5 individual cases over a period of 8 years (1 fibroma, 1 angiofibroma, 2 adenofibromas, 1 xanthous neurofibroma) the characteristics of the rare intrapulmonary fibroma and the therapeutic consequences are discussed. any suspicious tumor demands a thoracotomy with careful preoperative treatment and the subsegment or segment resection depending on the histological diagnosis reported during the procedure.	1997	179163
[use of temperature, trypsin and biological tests for the intraspecies differentiation of local strains of aujeszky's disease virus].	studies were carried out with 8 strains of aujeszky's disease virus using a temperature test (50 degrees c for 1 hour), a trypsin test (0.5 mg per cu. cm at 37 degrees c 1 hour), and a biologic test. the strains were isolated from the brain of dead pigs that have presumably been affected with encephalitis. they proved sensitive when studied with the temperature and the trypsin tests sharply lowering their titer. the viruses isolated from pneumonic foci in the lungs of pigs in which the disease h ...	1975	179192
structure of the mengo virion. iv. amino- and carboxyl-terminal analyses of the major capsid polypeptides.		1997	179198
[effect of isoproterenol on lipolysis and camp concentration in peripheral skeletal muscles of the rat].		1975	179243
blindness caused by photoreceptor degeneration as a remote effect of cancer.	three postmenopausal women developed photoreceptor degeneration one to four months preceding or following discovery of an anaplastic tumor. two patients had transitory visual obscurations and bizarre visual sensations. ring scotomas progressed to severe visual field loss. retinal arteries were markedly narrowed. electroretinograms revealed almost total absence of response in one patient, and another complained of the recent onset of night blindness. in all three patients severe degeneration of t ...	1997	179323
angiotensin ii binding to renal glomeruli from sodium-loaded and sodium-depleted rats.	125i-labeled angiotensin ii (125i-labeled aii) and [3h]angiotensin ii ([3h]aii) bind specifically to isolated rat glomeruli. three groups of receptor sites could be defined by the kd value (7.1 +/- 0.3 x 10(-11, 3.4 +/- 0.2 x 10(-10), and 1.6 x 10(-9) m, respectively) and the number of receptor sites (11.6 +/- 1.2, 29.4 +/- 3.9, and 113.8 +/- 3.8 fmol/mg glomerular protein, respectively). both association and dissociation constants for 125i-labeled aii were greater than those for [3h]aii, but th ...	1976	179329
organizing a community department for academic radiology.		1997	179344
computed tomography of the normal and infarcted myocardium.	after intravenous administration of contrast agent, in vitro cardiac scanning showed a significant difference between the attenuation coefficients of the intracavitary blood pool and the myocardial wall, permitting clear delineation of the ventricular cavity. a substantial alteration in hematocrit permitted similar visualization of the intracavitary blood pool-myocardial wall interface. the attenuation coefficient of infarcted myocardium differed sufficiently from that of normal myocardium to re ...	1976	179347
caudal dislocation of the pons in the adult arnold-chiari malformation: an angiographic evaluation.	the position of the pons, determined angiographically, can be related to the clivus and sella. in adult patients with the chiari malformation, a caudal dislocation of the pons is frequently associated with the well known anomalously low position of the cerebellar tonsils. this finding may aid in the angiographic diagnosis of the chiari malformation.	1997	179349
the complication rate of catheter angiography by direct puncture through aorto-femoral bypass grafts.	a search of the literature revealed no documentation of the complication rate associated with percutaneous catheterization of aorto-femoral bypass grafts in the arteriographic evaluation of graft patency. the authors compared the complication rates of 29 consecutive arteriograms performed through grafts (group i) with 40 arteriograms performed on non patients (group ii). neither group had any significant complications, indicating the safety of percutaneous catheterization of the graft site.	1997	179352
proceedings: bone imaging using a gadolinium-153 source and a xenon-filled multiwire proportional counter as detector.		1997	179400
proceedings: an overview of clinical applications of photon absorptiometry.		1997	179420
proceedings: skeletal mass in rheumatoid arthritis: a comparison with forearm bone mineral content.		1997	179425
[myeloperoxidase synthesis in white mouse leukocytes].	h3-leucine incorporation in myeloperoxidase (mpo) and into total soluble protein (tsp) from leucocytes of peritoneal exudate of mice was determined by immunological procedure. maximal h3-leucine incorporation was observed within 48 hours and 16 hours of exposition for mpo and tsp respectively. half-life period of mpo was 2,6 days which is comparable with the duration of neutrophils maturation up to the stage of metamyelocyte. apparently, no essential formation of mpo takes place at the level of ...	1976	179619
inhibition by saccharin of glucose-6-phosphatase: effects of alloxan in vivo and deoxycholate in vitro.	inhibition by saccharin of rat liver glucose-6-phosphatase (ec 3.1.3.9) generally decreased as the ph increased in the range ph 4-8. this pattern was exhibited by homogenates from control and alloxan-treated animals assayed each in the absence and presence of 0.2% (w/v) deoxycholate. saccharin inhibited in competitive fashion with respect to glucose-6-phosphate (glucose-6-p). there was a small increase in km (glucose-6-p) but not k1 (saccharin) values in alloxan-treated rats when assays were con ...	1976	179681
[the differentiation of h. influenzae and. h. parainfluenzae (author's transl)].		1976	179719
[dynamics of sleep and the waking state after labyrinthine deafferentation].	the author carried out studies on awake state and sleep (slow and paradoxal) after lybyrinth deafferentation. the states were evaluated by behavior, eeg, myogram and eye movements. the labyrinth defferentation was performed in combination (chemical and mechanical). bilateral labyrinth deafferentation reduced the duration of the awake state from 30% to 17%, p less than 0.001. the slow sleep was increased at the same time but there was no statistical significance. the parodoxal sleep was due both ...	1976	179775
activation of thyroid adenyl cyclase by antisera to thyroid plasma membrane preparations.	adenyl cyclase was assayed in a series of plasma membrane fractions prepared from bovine thyroids using sucrose density gradient ultracentrifugation. the activity of adenyl cyclase in the plasma membranes was found to be stimulated several-fold by antisera raised in rabbits against the plasma membranes and by purified igg prepared from these antisera. the data indicate that the antibodies to thyroid plasma membrane manifest properties similar to those of the immunoglobulins long-acting thyroid s ...	1976	179789
daily variation in concentration of plasma corticosteroid in hypophysectomized rats.	a daily variation in the concentration of plasma corticosteroid hormone is present in hypophysectomized rats implanted with pellets of adrenocorticotropic hormone (acth) and thyroxine. although acth is necessary to maintain a functional adrenal, and thyroxine is required to permit the expression of the plasma corticosteroid rhythm, a normal daily variation in plasma corticosteroid concentration does not appear to depend on the periodic release of pituitary hormones.	1976	179796
role of sodium and potassium in aldosterone binding of kidney receptors in the rat.	an increase of the sodium concentration produced a diminished binding of labeled aldosterone to kidney receptors in both in vivo and in vitro conditions. the elevation of potassium level did not change the binding capacity of kidney nuclear receptors for aldosterone. hypernatraemia-induced decrease of aldosterone uptake was significant in the nuclear fraction of both medullary and cortical region of the kidney but did not show remarkable changes in the uptake of cytosol fraction. the transfer of ...	1975	179799
steroid production by quartered and capsular rat adrenal gland in response to haemorrhage.	60 min after rapid bleeding (1.5--2.0 per cent of b. w.) both aldosterone and corticosterone production rate by quartered rat adrenals were found to be elevated. however, no difference was observed in the rate of aldosterone and corticosterone production by capsular adrenals of sham operated and hypovolaemic rats. corticosterone production rate by decapsulated adrenals was much more higher after haemorrhage than in the control group. the same alterations could be observed incubating adrenal tiss ...	1975	179800
electron-spin-resonance studies of a chlorpromazine derivative bound to dna fibres.	solutions of dna, spin-labelled with the radical cation of chlorpromazine, were used to produce oriented species of fibres pulled from a gel obtained by ultracentrifugation. the electron spin resonance spectra, recorded at x and q band frequencies, are given for both gel and fibres; 14n hyperfine coupling parameters were obtained by computer fitting. the spectra are explained in terms of a strongly immobilized label having one principal hyperfine tensor axis parallel to the axis of the dna helix ...	1976	179819
cushing's syndrome or obesity. bilateral adrenal hyperplasia in a boy 10 years of age.	a rare case of the cushing syndrome, due to bilateral adrenal hyperplasia is described. because of generalized obesity, normal height, normal bone age and family history of obesity, a boy 10 years of age had at first been misdiagnosed as simple obesity. a reduction in height velocity, advancement of bone age and development of precocious pseudopuberty led to a more detailed biochemical investigation and to the correct diagnosis. the clinical picture can be misleading in the differential diagnosi ...	2003	179822
alterations in the characteristics of 2-deoxy d-glucose transport into cultured human glioma cells during cell growth.		1976	179828
the link between charge separation, proton movement and atpase reactions.		2003	179861
esr determination of mn++ uptake and binding in mitochondria.		1975	179871
hypoglycemia in diabetics.	hypoglycemia in diabetes can be divided into 1) spontaneous hypoglycemic reactions due to absolute or relative overproduction of endogenous insulin or some other blood glucose-lowering substance, as in islet cell adenoma or carcinoma, latent or protodiabetic conditions, (extrapancreatic) tumors and pituitary and/or adrenal disorders; and 2) hypoglycemia caused by exogenous, i.e. therapeutic, measures. the problem of hypoglycemia in insulin-treated diabetics is far from being solved. as revealed ...	1984	179924
reversible inactivation of phenylalanine hydroxylase by catecholamines in cultured hepatoma cells.	phenylalanine hydroxylase in reuber h4 hepatoma cell cultures can be rapidly inactivated by the addition of epinephrine, norepinephrine, dopamine, or 3,4-dihydroxyphenylalanine, in order of decreasing effectiveness, to the culture medium. the enzyme was 50% inactivated in 1 hour by 25 mum (r)-epinephrine or 45 mum (r)-norepinephrine in the medium. high concentrations of epinephrine caused a 70% inactivation in 15 min. phenylalanine hydroxylase appears to be reversibly inactivated by epinephrine ...	1976	180004
testosterone-estradiol-binding globulin in patients with turner's syndrome: effects of estrogens and acute growth hormone administration.	the tebg activity of plasma from patients with turner's syndrome was measured quantitatively using polyacrylamide gel electrophoresis. human growth hormone administration did not significantly change the plasma tebg levels. however, oral replacement therapy with estrogens elevated plasma tebg within 3 days; after 9 days these levels reached a maximum of three- to four-fold greater than that observed at a time prior to therapy.	1976	180042
study of title 19 (medicaid) coverage of sterilization.		1985	180077
malignant fibrous histiocytoma. a rare soft tissue tumor of the foot.		1985	180082
william montagna lecture. cyclic nucleotides and epidermal cell proliferation.		1985	180185
the process of cholesterol cholelithiasis induced by diet in the prairie dog: a physicochemical characterization.	the rapid induction of cholesterol cholelithiasis in a new experimental model, the prairie dog, has recently been reported by two groups. in this model they were able to induce gallstones in as brief a period as 2 weeks, using a 1.2 per cent cholesterol diet. this unprecedented time intensity or telescoping of the induction process provided a unique opportunity for observation of physicochemical changes occurring rapidly over a short period of time and to correlate these with degree of biliary c ...	1976	180214
study of the effect of acth and cortisol on the plasms lipids in man using thin-layer chromatography.	this is a study of the action of acth and cortisol on plasma lipids using thin-layer chromatography and evaluation by densitometry. we have studied the action of 50 i.u. of acth in eight healthy individuals. we found an increase of free fatty acids after four hours and of triglycerides and esterified cholesterol after six hours. free cholesterol levels declined after another six hours, the decrease becoming more intense after twenty-four hours. after twenty-four hours lecithin underwent a declin ...	1976	180223
enhancement of polysome formation and protein synthesis in sendai virus-infected cells.	a considerable stimulation of total protein synthesis in sendai virus-infected chicken fibroblasts occurred 18 h after infection. the stimulation of synthesis was shown to be due mainly to the synthesis of virus-specific proteins; the synthesis of host proteins was either unchanged or slightly enhanced. the level of functional polyribosomes in virus-infected cells was also increased as compared to that in mock-infected control while the number of free 80s ribosomes was proportionally decreased.	1976	180240
characterization of two particle types of calf rotavirus.	two distinct types of rotavirus particle were isolated in caesium chloride density gradients. the higher density particle banded at 1-38 g/ml and measured 55 +/- 0-4 nm in diameter while the less dense particle banded at 1-36 g/ml, measured 66 +/- 0-4 nm in diameter and appeared to possess an extra outer capsid layer. some forms intermediate between the two types were seen. since the two particles had a similar but not identical morphology and polypeptide composition, they were considered to be ...	1976	180243
decrease of homovanillic, dihydroxyphenylacetic acid and cyclic-adenosine-3',5'-monophosphate content in the rat caudate nucleus induced by the acute administration of an aminoacid mixture lacking tyrosine and phenylalanine.		1976	180254
antibodies to epstein-barr virus in neurological diseases.	an association of evidence of epstein-barr virus (ebv) infection in 3 different cases of neurological disease not related to infectious monomucleosis is reported. a rise in antibody titres to ebv-viral capsid antigen (vca) and early antigen (ea) in the serum and csf was demonstrated in a patient with acute encephalitis and in a patient with a psychotic-like organic brain syndrome. both patients demonstrated albuminocytological dissociation in the cerebrospinal fluid. igm antibodies specific to e ...	1976	180262
genetic markers in atherosclerosis: a review.	there is a growing number of lipoprotein markers recognized by immunological, electrophoretic, and other biochemical methods, and a beginning has been made on studying their modes of inheritance and linkage relations. suggestive but inconclusive evidence of a relation between the cerumen polymorphism and arteriosclerosis has been published. associations of the abo blood groups with cardiovascular disease and serum lipid levels have been established, but the exact relation to lipoproteins and ath ...	1985	180292
[surgery of cerebellar glioma].		1985	180308
[recurrence of wilms' tumor in a child].		1985	180325
diminished content of plasma membrane-associated myosin in transformed fibroblasts.		1986	180411
independence of beta-adrenergic and thyrotropin receptors linked to adenylate cyclase in the thyroid.		1986	180417
proposed structure for brain adenylate cyclase purified using blue dextran-sepharose chromatography.		1976	180424
relationship between receptor and mammary tumour virus production after stimulation by glucocorticoid.	a short exposure of primary cultures of mouse mammary tumour cells to glucocorticoids results in at least a three-fold stimulation of mammary tumour virus (mtv) production. specific interaction of glucocorticoids with the cytoplasmic and nuclear receptors can also be demonstrated. the biological potency of various steroids to stimulate mtv is related directly to the retention of the steroid-receptor complex in the nuclei. progesterone has a high affinity for the cytoplasmic receptor, is not reta ...	1976	180430
influence of bcg vaccination on the primary and transplantable hamster tumors induced by sv40 and on the specific sv40 virus-induced antitumor immunity.	the main purpose of the study was the estimation of the effect of bcg vaccination and bcg in the combination with the specific immunization with sv40 on the incidence of primary and growth of transplantable sv40-induced tumors in syrian hamsters. different bcg vaccine preparations containing 60--100 millions of viable mycobacteries per 1 mg were used. it has been demonstrated that one and two intradermal injections of bcg (0.25 mg per animal) during the latent period in syrian hamsters inoculate ...	1976	180441
effect of nucleosides on the synthesis of nucleic acids and proteins in ehrlich ascites carcinoma cells.	the synthesis of nucleic acids and proteins in whole cells of ehrlich ascites carcinoma was inhibited by adenosine and by several natural-adenosine-related compounds. the inhibitory effect of adenosine was more pronounced than that of other nucleosides tested (guanosine, inosine, cytidine, uridine and thymidine). the synthetic processes examined were only moderately inhibited by adenine nucleotides (atp, adp, amp, nad, cyclic 3',5'-amp and its dibutyryl derivative). respiration and aerobic glyco ...	1986	180442
[tubular inclusions in the lymphocytes in a case of "hairy cells leukemia" (author's transl)].	a tubular inclusion (hovig type) was found in the cytoplasm of the blood lymphocytes of a case of hairy cells leukemia. its cytochemical and ultrastructural features are described ; its signification remains unknown.	1986	180478
computerized tomography in the detection of intracranial metastases in children.	computerized tomography brain scans produce sectional tomograms of the brain substance which demonstrate intracranial lesions. the procedure is safe and painless, and can be done on an outpatient basis. three children with malignant disease had intracranial metastases demonstrated using this technique during a recent six-month period at the cleveland clinic.	1986	180488
congenital cytomegalovirus infection.		1976	180500
a transovarian transmission study of marek's disease in japanese quail.	experiments were conducted to determine if transovarian transmission of the jm strain of marek's disease virus (mdv) occurs in japanese quail. in one experiment, parent quail were infected with mdv when one-day-old; in another experiment, parent quail were infected when seven weeks old. no precipitating antigen or cytopathic or infective agent was isolated from the egg yolks, embryos, newly hatched quail, or progeny quail of the infected parents. during the eight weeks observation period, the pr ...	1975	180501
specific and non-specific immunosuppression in chickens.	specific immunosuppression, caused by the passive transfer of immune sera, and non-specific immunosuppression, caused by acth, were investigated for possible interactions. the data confirm earlier studies which show that both types of suppression when administered independently cause reductions in humoral immune responsiveness. however, when both suppressive methods were administered simultaneously a level of suppression occurred which was not greater than that caused by either method alone. add ...	1975	180505
affinity isolation of cultured tumor cells by means of drugs and hormones covalently bound to glass and sepharose beads.	isoproterenol, corticotropin (acth), and triodothyronine immobilized on glass and sepharose beads by diazotization procedures have been shown to interact with cultured tumor cells of "target tissue" origin. cells used were rat glioma cells (c6), rat adrenal tumor cells (y-1), and rat pituitary tumor cells (gh3). the rat glioma cells bound principally to immobilized isoproterenol, whereas the rat adrenal tumor cells bound to immobilized corticotropin, and rat pituitary tumor cells bound to immobi ...	1976	180534
rem sleep deprivation and exploration in young rats.		1976	180557
angiography of nonfunctioning islet cell tumors of the pancreas.	two cases of nonfunctioning islet cell tumors were documented angiographically and histologically. the manifestations of islet cell tumors, with emphasis on the nonfunctioning type, are discussed, as are the differences between the functioning and nonfunctioning types.	1986	180562
[epidemiological aspects of cytomegalovirus infections].		1975	180573
nuclear protein kinase of brain: effect of s-100 protein.	the non-histone chromosomal protein fraction isolated from purified brain nuclei possesses protein kinase activity. 93% of this activity is lost by heating at 80 degrees c for 5 min. camp does not affect the reaction, but cgmp is inhibitory. in the presence of s-100, an acidic brain-specific protein, phosphate incorporation is enhanced 3 to 4 fold. bovine serum albumin has no effect whereas histone inhibits activity.	1976	180574
nitrogenase of azotobacter chroococcum. kinetics of the reduction of oxidized iron-protein by sodium dithionite.	the kinetics of the reduction of oxidized fe-protein of nitrogenase from azotobacter chroococcum by sodium dithionite were studied by stopped-flow and rapid-freezing e.p.r. (electron-paramagnetic-resonance) spectroscopy. the appearance of the gav. = 1.94 e.p.r. signal (0.24 electron integrated intensity/mol) was associated with a one-electron reduction by so2--with k greater than 10(8)m-1-s-1 at 23 degrees c. a value of k = 1.75s-1 was obtained for the rate of dissociation of s2o42- into 2so2-- ...	1976	180978
on the utilization of l-glutamine by glutamate dehydrogenase.		1976	180990
in vivo activation by polymyxin b of phospholipase from pseudomonas aeruginosa and escherichia coli.		1976	181357
disruption of the fucose pathway as a consequence of genetic adaptation to propanediol as a carbon source in escherichia coli.	in escherichia coli, l-fucose is dissimilated via an inducible pathway mediated by l-fucose permease, l-fucose isomerase, l-fucose kinase, and l-fuculose 1-phosphate aldolase. the last enzyme cleaves the six-carbon substrate into dihydroxyacetone phosphate and l-lactaldehyde. aerobically, lactaldehyde is oxidized to l-lactate by a nicotinamide adenine dinucleotide (nad)-linked dehydrogenase. anaerobically, lactaldehyde is reduced by an nadh-coupled reductase to l-1,2-propanediol, which is lost ...	1976	181364
thyroid peroxidase, thyroglobulin, camp and dna in human thyroid.	tissues from normal thyroid, euthyroid multinodular goiter, toxic goiter, hashimoto's thyroiditis, thyroid adenoma, and carcinoma were examined for their content of deoxyribonucleic acid (dna), thyroid peroxidase activity (tpa), thyroglobulin (tg), and adenosine 3',5'-cyclic monophosphate (camp). compared with normal thyroids dna was increased in the neoplastic tissues and decreased in euthyroid multinodular goiter. quantitative changes of thyroglobulin were observed, especially in the thyroid t ...	1976	181398
toluene diisocyanate (tdi) pulmonary disease: immunologic and inhalation challenge studies.	clinical and serologic effects of tdi exposure were studied in 112 occupationally exposed plant workers. sera were obtained before and after commencement of tdi production. all subjects were skin-tested with common inhalant allergens and a tdi-hsa conjugate. total eosinophil counts, immunoglobulin quantitations, and specific antibody assays by pca, p-k, and radioimmunoassay were performed. clinically "sensitive" individuals were tested by provocative inhalation challenge with from 0.005 ppm to t ...	1981	181412
effect of human immune serum globulin on infectivity of hepatitis a virus.	a standard preparation of immune serum globulin containing a titer of immune adherence hemagglutination hepatitis a antibody of 1:3,200 neutralized the infectivity of ms-1 serum. an inoculation of ms-1 serum was followed by the following evidence of hepatitis a infection in eight of 14 seronegative recipients: (1) abnormal values for serum aspartate aminotransferase after an incubation period of 29-42 days, and (2) no detectable immune adherence hemagglutination hepatitis a antibody (less than 1 ...	1976	181498
growth on d-arabitol of a mutant strain of escherichia coli k12 using a novel dehydrogenase and enzymes related to l-1,2-propanediol and d-xylose metabolism.	escherichia coli k12 cannot grow on d-arabitol, l-arabitol, ribitol or xylitol (reiner, 1975). using a mutant of e. coli k12 (strain 3; sridhara et al., 1969) that can grow on l-1,2-propanediol, a second-stage mutant was isolated which can utilize d-arabitol as sole source of carbon and energy for growth. d-arabitol is probably transported into the bacteria by the same system as that used for the transport of l-1,2-propanediol. the second-stage mutant constitutively synthesizes a new dehydrogena ...	1976	181526
analysis of herpesvirus dna substructure by means of restriction endonucleases.	the mol. wt. and molar ratios of the hind iii and hpa i fragments of hsv-1 dna and the eco ri fragments of hsv-2 dna have been determined. results obtained suggest that dna isolated from both hsv-1 and hsv-2 consists of molecules with four different sequence arrangements which are present in similar amounts. our explanation of the cleavage patterns of these four genome arrangements with the different restriction enzymes is presented. some of the possible implications of these four genome arrange ...	1976	181534
assessment of effect of starvation, glucose, fatty acids and hormones on alpha-decarboxylation of leucine in skeletal muscle of rat.	the present investigations of rates of oxidation of [u-14c] or [1-14c]leucine by homogenates of gastrocnemius muscle of fed and starved rats have indicated that 14co2 production is mainly the result of alpha-decarboxylation of leucine in this tissue. this incomplete oxidation was not the result of imparied tricarboxylic acid cycle since the oxidation of palmitate proceeded to completion within the experimental conditions. in the subsequent studies, the effect of altered nutrition and metabolic f ...	1976	181544
comparative membrane microviscosity of fish and mammalian rhabdoviruses studied by fluorescence depolarization.	the microviscosity of the hydrophobic region of the membrane of infectious hematopoietic necrosis virus was determined using fluorescence depolarization analysis of the probe 1,6-diphenyl-1,3,5-hexatriene and was found to be much lower at 37 c than that of another rhabdovirus, vesicular stomatitis virus. however, the microviscosity of this fish virus at 18 c, the temperature at which it was grown, corresponded to the microviscosity of vesicular stomatitis virus at 37 c. data obtained with the fi ...	1976	181597
[experimental aortic stenosis, its subsequent correction and the activity of oxidative enzymes in the myocardium].	the activity of the respiratory enzymes of myocardial mitochondria--succinatedehydrogenase and cytochromixidase--was studied in experimentally induced aortic stenosis and after its elimination in 98 mongrel dogs. the observation period of stenosis was 1, 15, 30 and 60 days, and after its elimination--1, 7, 15 and 30 days. the activity of the enzymes in question was found to grow after the production of aortic stenosis. the highest level of their enzymatic activity was observed on the 15th day af ...	1976	181629
antidiuretic hormone and water transfer.		1981	181633
delayed clearance of chylomicron remnants following vitamin-a-containing oral fat loads in broad-beta disease (type iii hyperlipoproteinemia).	chylomicron "remnants" are formed by the selective removal of triglyceride catalyzed by lipoprotein lipase. to investigate a possible defect in the clearance of these remnants in the pathophysiology of broad-beta disease (type iii hyperlipoproteinemia), subjects with this disorder and comparison subjects with endogenous hypertriglyceridemia (and type iv lipoprotein patterns) ingested an oral fat load (corn oil: cocoa butter, 1:1, 50 g/sq m) containing retinyl ester, 100 mg, with or without 15 mu ...	1981	181657
the effect of bacterial infections on ketone concentrations in rat liver and blood and on free fatty acid concentrations in rat blood.	the concentrations of cytoplasmic lactate and pyruvate and the nad+/nadh ratio and the concentrations of mitochondrial acetoacetate, beta-hydroxybutyrate, and the nad+/nadh ratio were determined in normal, fed, and fasted rats, and in rats infected with streptococcus pneumoniae, francisella tularensis, and salmonella typhimurium. the various infections were found to have little or no effect on the cytoplasmic parameters. in normal rats, fasting caused a marked increase in blood and hepatic keton ...	1976	181658
[functional exploration of the adrenal gland activity in the hypothalamo-hypophyseal-adrenal axis].		1981	181665
interaction of digitoxigenin with lecithin membranes.	the binding of digitoxigenin to lecithin model membranes was investigated by application of electron spin- and nuclear magnetic resonance methods. a digitoxigenin spin-label derivative was found to bind specifically to the pseudohexagonal rigid lattice of lecithin membranes. the binding is accomplished by some of the structural features which are required for the biological activity of cardiac glycosides. digitoxigenin has a procooperative effect on dipalmitoyl-lecithin membranes. the induction ...	1976	181688
experimental myasthenia due to alpha-bungarotoxin.	neuromuscular transmission was studied electrophysiologically in rabbits intoxicated by alpha-bungarotoxin, a specific inhibitor of acetylcholine receptor. the findings consisted of a slight reduction in amplitude of single evoked muscle action potentials, a decrement in amplitude of successive evoked muscle action potentials post-tetanic potentiation and exhaustion, edrophonium reversal, and no change of muscle action potentials evoked by direct stimulation of the muscle. these were similar to ...	1976	181695
triplet states and photosynthesis.		1981	181767
[evaluation of the action of ointment in 393-s-12 chronic cutaneous ulcers].		1981	181794
the regulation of insulin secretion.		1981	181811
a protein-binding assay for direct determination of adenosine 3',5'-monophosphate in amniotic fluid, cerebrospinal fluid, plasma, and urine.	an adenosine 3',5'-monophosphate (cyclic amp)-binding protein was isolated from bovine skeletal muscle. this preparation showed maximum binding capacity for cyclic amp at the physiological ph of amniotic fluid, cerebrospinal fluid, and plasma and had a high association constant of 1.4x10(9) 1/mol. this preparation of binding protein, together with albumin and edta in the assay buffer, gave a sensitive and specific competitive protein-binding assay that permitted direct determination of cyclic am ...	1976	181838
[ligation of lymphatic ducts in treatment of arteriosclerosis. 550 operated cases reported over a period of 9 years].	in all diseases where there is an important loss of lymph, e.g. chylothorax, chyloperitoneum, exsudative enteropathy chyloduodenal fistula, we observed not only a fall in the serum proteins and calcium, but also a fall in lipids and cholesterol. we first carried out ligature of the lymphatic ducts in numerous dogs. since 1966, we have carried out this ligature in 550 arteriosclerotic patients, aged less than 52 years. the metabolic changes observed over a period of 9 years were very marked. clin ...	1976	181846
[application of scanning electron microscopy in the evaluation of iron content of human synovial membrane].		1976	181851
[aujezky's disease in the field and vaccination against the disease (author's transl)].	a rather extensive outbreak of aujeszky's disease in the area served by the above veterinarians is reported. of 252 pig-breeding farms, eighty-two were contaminated. the other herds (170) were partly (81) vaccinated against the disease with the bartha strain. unlike de non-vaccinated group, the immunized herds showed few of any losses. in view of this fact it is concluded that aujeszky's disease vaccination is a useful procedure (even in a contaminated environment).	1976	181864