Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| preparation, characterization, and immunogenicity of conjugates composed of the o-specific polysaccharide of shigella dysenteriae type 1 (shiga's bacillus) bound to tetanus toxoid. | the background for developing conjugate vaccines for shigellosis composed of the o-specific polysaccharide (o-sp) bound to a protein is described elsewhere (c. y. chu, r. schneerson, and j. b. robbins, submitted for publication). briefly, there is direct evidence for type (lipopolysaccharide [lps])-specific protection after infection with the wild type or with attenuated strains of shigellae. prospective studies of israeli armed forces recruits show a correlation between preexisting serum immuno ... | 1991 | 1937803 |
| disturbed metabolism of glucose and related hormones in familial amyloidotic polyneuropathy: hypersensitivities of the autonomic nervous system and therapeutic prevention. | regulation of glucose metabolism was evaluated by oral glucose tolerance test (ogtt) in patients with familial amyloidotic polyneuropathy (fap). upon oral administration of a loading dose of glucose, plasma levels of glucose, insulin and glucagon changed abnormally in all fap patients tested. although plasma levels of glucose and insulin in the fasted patients were within normal ranges, 33% of fap patients showed hypoglycemia after transient hyperinsulinemia during the examination. furthermore, ... | 2007 | 1940028 |
| doping control of anabolic steroids. | 2006 | 1940836 | |
| treatment of shigellosis. | 1991 | 1941398 | |
| external fixators and their use. | 2007 | 1941748 | |
| annotated list of ticks (acari: ixodidae, argasidae) reported in peru: distribution, hosts, and bibliography. | a literature review and compilation of the tick specimens found in peru and now held in the national tick collection was carried out to develop a working list of the tick species likely to be found in peru. evidence of 44 species (29 ixodidae, 15 argasidae), was found; representatives of 40 species are held as reference specimens. this report adds 14 species to the previously published list. | 2007 | 1941924 |
| a new form of autosomal dominant arthrogryposis. | we report a man and his son with congenital limb contractures, limitation of ocular movements, and an electroretinal abnormality. they appear to have an autosomal dominant form of arthrogryposis, distinguishable from other previously classified forms of this disorder. | 1991 | 1941966 |
| [intubation of cadavers in medical training]. | 2007 | 1948930 | |
| [creatinine clearance as the foundation for clinical determination of kidney function in swine]. | comparative examinations of renal function using inulin- and endogenous creatinine-clearance tests in 5 pigs showed nearly identical values of glomerular filtration rate (gfr). based on this relation 79 healthy pigs, weighting 2 kg to 230 kg were investigated using the creatinine-clearance test for determination of normal values of gfr and urine flow rate (vu) as well as renal excretion (e), renal clearance (clr) and fractional excretion (fe) of urea, sodium, potassium, calcium, phosphorus, gluc ... | 1991 | 1948984 |
| raising health care capital through the public equity markets. | 2007 | 1949002 | |
| [the adhesion of pathogenic microflora on carbon sorbents]. | the adsorbing activity of granulated carbonic sorbents skn and kau, as well as their oxidated forms, containing protogenic carboxylic and phenolic groups with respect to shigella flexneri, salmonella typhimurium, escherichia coli, streptococcus aureus and pseudomonas aeruginosa pathogenic strains has been studied. as shown in this study, the process of interaction between microorganisms and carbonic sorbents has two stages. at the first stage the main role is played by long-distance electrostati ... | 1991 | 1950254 |
| [the dynamics of the formation of an infection focus in the intestines]. | the problem of the stability of the development of shigella population in the intestine, depending on the dose of the infective agent, is analyzed. the agent is reproduced in the intestinal mucosa in short cycles, starting with adhesion and followed by penetration, intracellular multiplication and, finally, emission of free bacteria and hulled tops of villi with shigella intracellular microcolonies. this form of emission maintains high concentration of bacteria and ensures, in case of the adhesi ... | 1991 | 1950279 |
| [the protective properties of the endotoxin protein]. | the isolation and properties of endotoxin protein, or lipid a-associated protein (lap), from shigella sonnei were described earlier (zh. mikrobiol. epidemiol. immunobiol., 1991, no. 4, pp. 11-17, and no. 7). in this report the data on its protective activity are presented. in experiments on mice one nanogram of lap injected i. v. protected 50% of the animals against i. p. challenge with 40 ld50 of virulent s. sonnei. guinea pigs injected s. c. with 10 micrograms of lap were protected against loc ... | 1991 | 1950285 |
| dynamic computed tomography and functional imaging in cerebral arterial occlusive disease: analysis in the chronic phase. | dynamic ct was conducted on 10 patients with internal carotid artery (ica) or middle cerebral artery (mca) occlusion or stenosis and 14 controls. all the patients were chronic phase and they only presented small infarctions on ct. those with ica or mca occlusions and insufficient collateral circulations showed delayed mean transit time and peak time of the affected side on functional image and in parameter analysis (p less than 0.01) compared with those of controls. a statistically significant p ... | 2001 | 1950468 |
| ototoxic effect of potassium canrenoate on the guinea pig cochlea. | potassium canrenoate (pc) is a diuretic with antialdosterone action, reducing the reabsorption of sodium in the efferent renal tubules. this drug has been reported to damage only the marginal cells of the stria vascularis in the cochlea. the perilymphatic space of the guinea pig cochlea was perfused with an artificial perilymph containing 5 x 10(-3) m potassium canrenoate. following the onset of perfusion, the endocochlear dc potential (ep) gradually declined to around 10 mv but did not become n ... | 1991 | 1950534 |
| a new manual method for assessing two-dimensional cancellous bone structure: comparison between iliac crest and lumbar vertebra. | we have developed a simple method for the direct analysis of two-dimensional trabecular structure. using this method, we have compared the structure of the left and right iliac crest and the second lumbar vertebra and studied the relationship between two-dimensional trabecular structure and the ultimate compressive stress of bone samples from the second lumbar vertebra. transverse cores were taken from the left and right iliac crests and second lumbar vertebrae of 35 subjects (12 females) who di ... | 2007 | 1950674 |
| a new role for radiologists in the development of cardiac surgery. | 2007 | 1950902 | |
| hypertensive emergencies. | a hypertensive emergency is a rare event in which an acute elevation of blood pressure causes rapid progressive end-organ damage. cardiovascular, renal and central nervous system syndromes may be associated with acute blood pressure elevations. prompt treatment with antihypertensive agents should be initiated while the patient is closely monitored. lowering the blood pressure too quickly can exacerbate symptoms and decrease organ blood flow. treatment must be individualized depending on the end ... | 2007 | 1950972 |
| the diagnostic accuracy of rapid dipstick tests to predict urinary tract infection. | this study summarizes the diagnostic accuracy data for dipstick nitrite and/or leukocyte esterase tests (the index tests) as predictors of bacterial urinary tract infection as defined by quantitative culture (the reference test). on-line search of the literature using the medlars database identified 1,017 citations, 51 of which were relevant and contained sufficient data for further analysis. from each citation, 2 x 2 tables of true-positive, true-negative, false-positive, and false-negative res ... | 2007 | 1951183 |
| jaw protruder muscles and condylar cartilage growth in the rat. | many studies have explored the role of the protrusive musculature in promoting growth at the condylar cartilage and the overall lengthening of the lower jaw, with emphasis on the lateral pterygoid muscle (lpm). the largely anteroposterior orientation of the superficial part of the masseter muscle (sm) in the rat suggests that it may also function as a protruder of the lower jaw. accordingly, it is possible that the action of the sm may play a part in the regulation of growth of the condylar cart ... | 1991 | 1951196 |
| orthodontic graduate education survey--1983 to 1989. | 2007 | 1951200 | |
| epidemiologic patterns of acute diarrhea and endemic shigella infections in children in a poor periurban setting in santiago, chile. | to prepare a field site for evaluating preventive interventions against endemic shigellosis, the authors followed prospectively a cohort of 360 children (90 each of children aged 0-11, 12-23, 24-35, and 36-47 months) in santa julia, a low socioeconomic area in santiago, chile, from november 1986 through april 1989 with twice weekly household visits for diarrheal disease; infants replaced children who reached 60 months of age. coprocultures on 2 consecutive days from children with diarrhea and fr ... | 1991 | 1951266 |
| indirect fertility analysis in painters exposed to ethylene glycol ethers: sensitivity and specificity. | semen analysis has proven useful in the clinical diagnosis of infertility and is the most widely used method of monitoring the effects of occupational exposure on male fertility. collection and analysis of semen samples in a field setting, however, require a highly motivated population and excellent technical resources, limiting the widespread application of the method. techniques of monitoring male worker fertility using questionnaires to avoid some of the difficulties of semen analysis have be ... | 2007 | 1951370 |
| static muscle contraction reflexly increases adrenal sympathetic nerve activity in rats. | little is known about the mechanisms responsible for activation of sympathoadrenal function during exercise. we hypothesized that sympathoadrenal discharge is activated at the onset of exercise by a reflex arising in the contracting muscle. adrenal sympathetic nerve activity (sna) was recorded during 1 min stimulation of the tibial nerve at two times motor threshold, before and during neuromuscular blockade, in 12 alpha-chloralose-anesthetized rats. static muscle contractions, induced by stimula ... | 1991 | 1951780 |
| dogs as sentinels for lyme disease in massachusetts. | an investigation of the relationship between incident human cases of lyme disease and seroprevalence of antibodies to b. burgdorferi in dogs was undertaken in order to determine whether dogs might serve as sentinels for lyme disease. | 1991 | 1951802 |
| family structure and child health. | 2007 | 1951818 | |
| the increasing supply of physicians in us urban and rural areas, 1975 to 1988. | despite the rapid growth of the us physician supply since the mid-1970s, it remains unclear whether physicians have spread into the most rural areas of the country. this report examines the urban-rural distribution of physicians between 1975 and 1988. | 2007 | 1951824 |
| pathogenicity and antigenic components of excysted giardia lamblia isolated from patients in riyadh, saudi arabia. | giardia lamblia cysts were isolated from patients in riyadh, saudi arabia. cysts and trophozoites (from axenically excysted cysts) were given orally by gavage to mice to establish the pathogenicity of the riyadh isolate. there was no effect of varying the dose of administered parasite on parasite excretion or morbidity. a typical pathologic pattern of giardiasis was demonstrated by histologic methods and electron microscopy. antigenic components of the riyadh isolate were compared with the portl ... | 1991 | 1951852 |
| growth of dengue type 2 virus isolates in human peripheral blood leukocytes correlates with severe and mild dengue disease. | we tested three dengue type 2 (den-2) isolates from children with clinically apparent but mild secondary dengue infections, and 10 isolates from children with moderately severe dengue hemorrhagic fever, and noted significant growth differences in peripheral blood leukocytes, but not in c6/36 cells. we also observed cytopathic effects in c6/36 cells that correlated with disease severity. these preliminary observations suggest the possibility that viral factors, whether surface antigens, attachmen ... | 1991 | 1951875 |
| hypothyroidism following combined treatment for hypopharyngeal and laryngeal carcinoma. | the development of hypothyroidism following combined treatment for pharyngeal and laryngeal cancer has received little attention in the literature. we prospectively studied 32 patients over 4 years to determine the incidence of such hypothyroidism and to examine the effect of hemithyroidectomy associated with a combined treatment modality. all patients were men with pharyngeal or laryngeal squamous cell carcinomas and no prior history of thyroid disease. treatment consisted of radical surgery (3 ... | 2007 | 1951886 |
| the infrahyoid musculocutaneous flap in head and neck reconstruction. | the infrahyoid musculocutaneous flap (ihmf), as first described by wang in 1986, is mainly nourished by the superior thyroid vessels through the perforators of the infrahyoid muscles (i.e., sternohyoid muscle, sternothyroid muscle, superior belly of the omohyoid muscle). this thin flap, usually extending from the hyoid bone to the sternal notch at the central part of the anterior neck, provides a skin island of about 4 by 8 cm. after these muscles have been divided from their origins, the flap c ... | 2007 | 1951898 |
| esophageal function and dysfunction. | 2007 | 1951923 | |
| [cytological examination of urethral and endocervical smears in the diagnosis of infections]. | cytologic studies of smears from 130 women suffering from various diseases, including 61 pregnant patients with gestoses, have shown structural changes of the cells in the smears from the endocervix and urethra, that permitted the diagnosis of mycoplasma infection in 43.8% of patients, chlamydia infection, 52.3%, and herpes simplex in 72.3% of patients; in 63.9% of patients these infections were combined. cytologic studies may be useful in the tentative diagnosis of urogenital infections, includ ... | 1991 | 1951977 |
| reliability of prognostic models in malignant melanoma. a 10-year follow-up study. | certain histologic and clinical features of malignant melanoma have been shown to be indicators of prognosis, both collectively and individually. even though the predictive value of these features is well established, long-term survival is occasionally seen in individuals with multiple poor prognostic factors. to further examine this phenomenon, histologic sections from 53 patients with malignant melanoma excised between the years 1977 and 1980 in whom reliable clinical follow-up data were obtai ... | 2007 | 1951981 |
| soft fibroma-like lesions on the legs of a patient with kaposi's sarcoma and lymphedema. | the case of a patient who developed multiple soft fibroma-like lesions on his lower extremities affected by lymphedema and kaposi's sarcoma is reported. to the best of our knowledge, the coexistence of these three pathologic processes is unusual and has never been described before in the literature. | 2007 | 1951987 |
| propofol for sedation of a spontaneously breathing infant. | 2007 | 1952021 | |
| severe earache following nitrous oxide anaesthesia. | 2007 | 1952025 | |
| synthesis and purification of radioactive fatty acylcarnitines of high specific activity. | micromole quantities of radiolabeled fatty acylcarnitines of high specific activity were synthesized by a simple one-step, one-pot acylation of [3h]carnitine in the presence of the respective fatty acid and acid chloride. the acylated product was isolated in high yield and high purity using liquid-liquid partitioning with isopropanol:hydrochloric acid:heptane (4:1:12 v/v) followed by butanol extraction. product recovery was 91% for octanoyl[3h]carnitine and 90% for palmitoyl[3h]carnitine and con ... | 2007 | 1952050 |
| [detection of the determinants of tetracycline a, b and c resistance in shigella and salmonella using dna probes]. | genetic determinants of tetracycline resistance of classes a, b and c were detected with dna probes labeled with radioactive phosphorus (32p) in shigella (44 strains) and salmonella (50 strains). it was shown that in the shigella strains the frequency of the tet a gene amounted to 66 per cent, the frequency of the tet b gene was equal to 84 per cent, the frequency of their combination was equal to 50 per cent and the frequency of the tet c gene was nil. in the salmonella strains the frequency of ... | 1991 | 1953181 |
| antigen recognition in the gastrointestinal tract: death to the dogma. | 2000 | 1955758 | |
| special issue on behavioral pharmacology. | 2007 | 1955809 | |
| causes of breast cancer misdiagnosis at physical examination. | 2740 consecutive breast cancers undergoing physical examination were reviewed. ninety-two subclinical cancers detected at mammography were excluded from further evaluation and the study focused on palpable false benign cancers. the sensitivity of physical examination varied according to t category (tis = 0.48, t1 = 0.70, t2 = 0.90, t3 = 0.89, t4 = 0.93), age (20-29 = 0.77, 30-39 = 0.58, 40-49 = 0.75, 50-59 = 0.84, 60-69 = 0.90, greater than 69 = 0.94) and operator (range 0.69-0.89), a significan ... | 1991 | 1956468 |
| the prophenoloxidase system and in vitro interaction of trypanosoma rangeli with rhodnius prolixus and triatoma infestans haemolymph. | the presence of the prophenoloxidase (propo) system in the haemolymph of rhodnius prolixus and triatoma infestans and the role played by trypanosoma rangeli in the in vitro activation of propo were tested. both r. prolixus and t. infestans whole blood preparations showed a very active propo system. the propo cascade of the two insect species were differentially activated by microbial-derived extracts: laminarin was a better activator of t. infestans haemolymph than of r. prolixus blood, and lipo ... | 1991 | 1956701 |
| differences in blood group b-specific mucinase activity between virulent and avirulent shigella flexneri 2a strains. | based on our previous findings we postulate that the production of blood group b-degrading mucinase by shigella flexneri 2a is related to virulence. the virulent s. flexneri 2a strain m4243 produced a blood group b mucinase which decreased the blood group b reactivity of germ-free mouse mucins by a factor of 16 and the b reactivity of human saliva by a factor of 32. avirulent s. flexneri 2a b-1, serologically similar, but not genetically identical to the m4243 strain, failed to degrade the blood ... | 1991 | 1961109 |
| [antioncogenes in tumors in children]. | 2006 | 1964040 | |
| distribution of insertion sequence is200 in salmonella and shigella. | two dna probes for the detection of insertion sequence is200 by either southern blotting or colony hybridization were constructed. one of the probes is a 300 bp ecori-hindiii fragment of is200 cloned onto pbluescript ks(+); the other is a tail-to-tail dimer of the same fragment cloned onto puc19. a survey of the presence of is200 among enteric bacteria revealed that more than 90% of the pathogenic or food-poisoning isolates of salmonella spp. examined contained one or more copies of insertion se ... | 1990 | 1964174 |
| h(+)-stimulated release of prostaglandin e2 and cyclic adenosine 3',5'-monophosphoric acid and their relationship to bone resorption in neonatal mouse calvaria cultures. | the addition of protons to the medium of neonatal mouse calvaria cultures stimulated bone resorption and release of calcium into the medium. in addition, added protons significantly increased the release of prostaglandin e2 (pge2) and cyclic adenosine 3',5'-monophosphoric acid (camp) from the bones. indomethacin significantly inhibited the release of calcium, pge2 and camp from proton-treated cultures. the positive control, parathyroid hormone (pth)-treated cultures, also gave rise to bone resor ... | 1990 | 1964815 |
| immunoglobulin profiles and antibacterial antibody levels in 50 patients a long time after posttraumatic splenectomy. | serum immunoglobulin and antibacterial antibody concentrations have been determined in 50 patients 2 to 20 years after posttraumatic splenectomy. the serum levels of igg, iga and igm were found to be significantly greater in the group of posttraumatic splenectomy patients than in that of the healthy controls. the serum ige concentrations did not differ statistically from that of the controls. the serum level of natural antibodies against intestinal bacteria were found to be elevated (shigella 1b ... | 1990 | 1966943 |
| the passerine bird song system as a model in neuroendocrine research. | in the neural system controlling song in passerine birds, gonadal steroid hormones have potent effects on neural growth and differentiation. during ontogeny, sex differences in the secretion of steroid hormones lead to dramatic sex differences in neuron number and structure. in adulthood, sex steroid hormones also cause a significant reorganization of neural circuits. these studies of hormone action have been influential in the development of the field of neuroendocrinology. | 2007 | 1974800 |
| neuropeptide families: an evolutionary perspective. | changes in the structure and function of five neuropeptide families during evolution are considered. the families of gonadotropin-releasing hormone (gnrh), corticotropin-releasing factor (crf), growth hormone-releasing hormone (gh-rh), somatostatin (ss), and vasopressin/oxytocin (vp/oxy) are used as models to illustrate the importance of a phylogenetic approach in understanding neuropeptide structure/activity relationships, precursors, processing, gene duplication, novel locations and functions, ... | 2007 | 1974805 |
| inhibition by anti-cd2 monoclonal antibodies of anti-cd3-induced t cell-dependent b cell activation. | anti-cd3 mab can activate t cells to help in b cell activation as detected by late events, such as maturation of b cells into ig-secreting cells (igsc), or by early events, such as b cell surface expression of the activation marker cd23. two different anti-cd2 mab each inhibited anti-cd3-induced t cell-dependent b cell activation in a dose-dependent fashion. neither irradiation of the t cells prior to culture nor depletion of cd8+ cells abrogated the inhibitory effects of anti-cd2 mab. despite t ... | 2007 | 1976440 |
| close relationships between neopterin and beta-2-microglobulin levels in intravenous drug abusers. | serum from 36 intravenous drug abusers without acquired immunodeficiency syndrome (aids) or aids-related complex were tested for concentrations of neopterin and beta 2-microglobulin. the seroprevalence of human immunodeficiency virus (hiv) antibody in this group was 50%. previous studies of this group showed that the hiv antibody positive patients had significant increases in hla-dr expression on peripheral blood lymphocytes and increases in serum soluble cd8 antigen. both neopterin and beta 2-m ... | 1990 | 1976599 |
| ovulation induction and neural tube defects. | 2005 | 1978153 | |
| competitive inhibition of magnesium-induced [3h]n-(1-[thienyl] cyclohexyl)piperidine binding by arcaine: evidence for a shared spermidine-magnesium binding site. | the polyamine competitive antagonist arcaine (1,4-diguanidino-butane) produced complete inhibition of basal [3h]n-(1-[thienyl] cyclohexyl)piperidine ([3h]tcp) binding, with an ic50 value of 4.52 +/- 0.93 microm. arcaine (5 and 10 microm) produced a decrease in the affinity without a significant change in the receptor density of [3h]tcp binding under equilibrium conditions. in addition, arcaine did not alter either n-methyl-d-aspartate-specific [3h] glutamate or strychnine-insensitive [3h]glycine ... | 1990 | 1978243 |
| the beneficial effect of cyclosporine preloading in renal transplants from hla-haploidentical living donors. | 2007 | 1989137 | |
| primary and metastatic pulmonary meningioma. | patient 1 was a 53-year-old man who had a very rare primary pulmonary meningioma that developed in the left lingular segment. when this report was written, 7 years had passed since he underwent operation, and no recurrence of the meningioma had been detected. in patient 2, a 61-year-old woman, multiple pulmonary metastases were confirmed 19 years after she had undergone operation for multiple cerebellar meningiomas, and the metastases were resected. after 2 years, multiple intraperitoneal metast ... | 1991 | 1991305 |
| controlled expression of the transcriptional activator gene virg in agrobacterium tumefaciens by using the escherichia coli lac promoter. | the agrobacterium virg protein is normally expressed from two promoters in response to multiple stimuli, including plant-released phenolics (at promoter p1) and acidic growth media (at promoter p2). to simplify the analysis of vir gene induction, we sought to create agrobacterium strains in which virg could be expressed in a controllable fashion. to study the possibility of using the lac promoter and repressor, we constructed a plasmid containing the lac promoter fused to the lacz structural gen ... | 1991 | 1991713 |
| theophylline toxicity. | 2007 | 1995754 | |
| in vitro studies on steroidogenesis in the presence of pregnenolone as precursors by the follicular tissue of the domestic fowl (gallus domesticus). | chicken granulosa and theca cells were isolated from f1 and f4-6 follicles 2-4 h before ovulation, and the amounts of progesterone, testosterone and oestradiol released in the medium during incubation for 3 h, in the presence or absence of pregnenolone as a percursor and stimulatory drugs or inhibitory drugs, were measured. progesterone synthesis by granulosa cells was stimulated with olh or theophylline. much more progesterone was synthesized when pregnenolone was added to the medium. the amoun ... | 1991 | 1997117 |
| virulence plasmids of enteroinvasive escherichia coli and shigella flexneri integrate into a specific site on the host chromosome: integration greatly reduces expression of plasmid-carried virulence genes. | the ability of enteroinvasive escherichia coli and shigella flexneri to cause disease depends on the presence of a large virulence plasmid (pinv). in this report we show that phn280, the pinv of the o135:k-:h- enteroivasive strain e. coli hn280, and pwr100, the pinv of s. flexneri serotype 5 strain m90t, are able to integrate into a specific site on the host chromosome. pinv-integrated hn280 and m90t strains required methionine (met-) to grow in minimal medium, were noninvasive, did not produce ... | 1991 | 1997431 |
| site and strand specificity of uvb mutagenesis in the sup4-0 gene of yeast. | 1991 | 2000411 | |
| comparative efficacy of ceftriaxone and ampicillin for treatment of severe shigellosis in children. | in a prospective randomized open study, ceftriaxone, 50 mg/kg per day, was compared with ampicillin, 100 mg/kg per day, both given for a period of 5 days, for the treatment of 40 children whose mean (+/- sd) age was 4.5 +/- 3.2 years and who had severe dysentery caused by shigella organisms. twenty patients were treated with ceftriaxone and 20 with ampicillin. both drugs were initially given intravenously for a period of 1 to 2 days and were continued intramuscularly, in the case of ceftriaxone, ... | 1991 | 2007941 |
| construction of aromatic dependent shigella flexneri 2a live vaccine candidate strains: deletion mutations in the aroa and the arod genes. | live shigella flexneri 2a vaccine candidate strains with deletion mutations in the aro genes were constructed. tn10-generated auxotrophic mutations were transduced from escherichia coli to s. flexneri 2a with bacteriophage p1cmcts. the tetracycline-sensitive derivatives of tn10 mutants obtained were selected on bochner's medium and checked by dna-dna hybridization using aroa and arod gene specific probes. the vaccine candidate strains were tested to assess the efficacy of protection in guinea-pi ... | 1991 | 2008803 |
| cancer in an ileoanal reservoir. | 1968 | 2013434 | |
| molecular characterization of the o-acetyl transferase gene of converting bacteriophage sf6 that adds group antigen 6 to shigella flexneri. | bacteriophage sf6 antigenically converts shigella flexneri serotype y strains (-;3,4) to type 3b carrying group antigen 6,3,4 by means of an o-acetylation of the o-antigenic polysaccharide chain. the gene for o-acetyl transferase of bacteriophage sf6 has been cloned, identified and sequenced. the predicted o-acetyl transferase protein encoded by this gene was found to consist of 333 amino acids, (37,185 daltons) and to have some similarity with the galactose-1-phosphate uridylyltransferase prote ... | 1991 | 2014005 |
| pathogenicity of foodborne salmonella. | salmonella remains a leading etiological agent in bacterial foodborne diseases. although human salmonellosis generally presents as a self-limiting episode of enterocolitis, the disease can degenerate into chronic and debilitating conditions. antibiotic treatment of uncomplicated salmonellosis is contra-indicated because it tends to prolong the carrier state. clinical management of systemic infections with newer drugs such as third-generation cephalosporins and quinolones is most promising, parti ... | 1991 | 2018704 |
| stress fiber-based movement of shigella flexneri within cells. | icsa (virg), a gene located on pwr100, the virulence plasmid of shigella flexneri serotype 5 (m90t), encodes a 120-kda outer membrane protein. this protein promotes a random intracellular movement of the bacteria and leads to the infection of adjacent cells by the formation of protrusions. this movement, which involves the nucleation, polymerization, and subsequent polarization of actin, is referred to as the ics phenotype (intra/intercellular spread). here we present evidence that a second, dis ... | 1991 | 2019438 |
| efficacy of aqueous extract of garlic & allicin in experimental shigellosis in rabbits. | the aqueous extract of garlic (allium sativum) and allicin both showed significant in vitro antibacterial activity against isolates of multiple drug-resistant shigella dysenteriae 1, sh. flexneri y, sh. sonnei and enterotoxigenic escherichia coli. the minimum inhibitory concentrations of the aqueous extract and allicin against sh. flexneri y were 5 and 0.4 microliters/ml, respectively. the two agents also showed promising in vivo antibacterial activity against sh. flexneri y when tested in the r ... | 1991 | 2022399 |
| antimicrobial effect of fermented ghanaian maize dough. | unhygienic conditions of a typical rural community in a developing country were simulated in the laboratory by inoculating fermented maize dough porridge with shigella flexneri and enterotoxigenic escherichia coli (etec). the antimicrobial effects of the different processes involved in the preparation of fermented maize dough porridge were assessed. the soaking process reduced the ph but no antimicrobial effect against shigella and etec was noted. unfermented maize dough did not inhibit any of t ... | 1991 | 2030095 |
| two novel virulence loci, mxia and mxib, in shigella flexneri 2a facilitate excretion of invasion plasmid antigens. | a bank of over 4,200 lacz protein fusions in shigella flexneri 2a was screened for fusions to temperature-regulated promoters. one mutant, bs260, was completely noninvasive on hela cells and mapped to a region on the 220-kb virulence plasmid in which we had previously localized several avirulent temperature-regulated operon fusions (a.e. hromockyj and a.t. maurelli, infect. immun. 57:2963-2970, 1989). the phenotype of bs260 was similar to that of the previously identified mxi (membrane expressio ... | 1991 | 2037361 |
| dose-related effects of prenatal 5-methoxytryptamine (5-mt) on development of serotonin terminal density and behavior. | our previous studies with a tissue culture model of neuronal development have shown that the development of serotonin neurons is dependent, at least in part, on the stimulation of high affinity serotonin receptors. one receptor inhibits the outgrowth of neurons, while the other promotes it. the present study was therefore undertaken to replicate these findings in a whole animal model system. pregnant sprague-dawley rats were treated from gestational day 12 until birth with 0.1, 1.0 or 3.0 mg/kg ... | 1991 | 2040080 |
| four decades of shigellosis in israel: epidemiology of a growing public health problem. | despite the improved standard of living in israel, shigellosis remains a common disease. examination of trends in the incidence of shigellosis in israel between 1951 and 1987 showed a period of declining rates followed by an increase in the reported incidence beginning around 1969. this increase was mainly due to shigella sonnei; rates of infection with shigella flexneri remained relatively constant. trends showed marked differences between age groups and between ethnic groups. in comparison, th ... | 1991 | 2041956 |
| abrogation of dominant glucose intolerance in sjl mice by a growth hormone transgene. | glucose tolerance was studied in transgenic mice (sjl x c57bl/6) expressing human gh under the control of a housekeeping promoter. parental sjl mice were found to harbour a dominant allele, termed here glid, determining glucose intolerance in pure-bred animals and in f1 hybrids with glucose-tolerant c57bl/6 mice. blood glucose levels in transgenic sjl x c57bl/6 hybrid mice were well controlled following glucose challenge, whereas non-transgenic hybrids failed to control their glucose adequately. ... | 1991 | 2043241 |
| mind over muscle. | 1991 | 2044511 | |
| effects of order of presentation of exercise intensities and of sauna baths on perceived exertion during treadmill running. | thirteen male subjects performed a running test on the treadmill consisting of four standard exercise intensities [65%, 75%, 85%, 95% maximal o2 uptake (vo2 max)] presented in ascending, descending or random order. at the end of each exercise intensity, o2 consumption, heart rate (fc), venous blood lactate concentration [( ia]b) and perceived exertion were assessed. this last variable was determined according to the borg nonlinear cr-20 scale. the same variables were also determined during exerc ... | 2007 | 2044527 |
| o2 uptake in hyperthyroidism during constant work rate and incremental exercise. | to investigate the effect of hyperthyroidism on the pattern and time course of o2 uptake (vo2) following the transition from rest to exercise, six patients and six healthy subjects performed cycle exercise at an average work rate (wr) of 18 and 20 w respectively. cardiorespiratory variables were measured breath-by-breath. the patients also performed a progressively increasing wr test (1-min increments) to the limit of tolerance. two patients repeated the studies when euthyroid. resting and exerc ... | 2007 | 2044536 |
| gentle exercise with a previously inactive muscle group hastens the decline of blood lactate concentration after strenuous exercise. | the aim of this study was to elucidate the mechanism by which the disappearance of blood lactate following severe exercise is enhanced during active recovery in comparison with recovery at rest. rates of decline of arterialised venous blood lactate concentrations in man after maximal one-leg exercise were compared during four different modes of recovery: passive (pr), exercise of the muscles involved in the initial exercise (sl), exercise of the corresponding muscles in the hitherto-inactive leg ... | 1991 | 2044538 |
| glucagon and clonidine testing in the diagnosis of pheochromocytoma. | we assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor. in the glucagon stimulation test, blood was sampled 2 minutes after intravenous injection of 0.28 mumol (1 mg) glucagon, and in the clonidine suppression test, blood was sampled 3 hours after administration of oral clonidine, 1.30 mumol (0.3 mg)/70 kg body wt. baseline levels of catechols in antecu ... | 2007 | 2045133 |
| [health indicators in urban areas. variations in function of social coherence of the geographic areas used]. | the detection of health inequalities in the urban environment and their magnitude depends to a great extent on the internal social coherence of the geographical division used. using an existing social map of alicante which divides the city into basic units for social intervention (busi), we have compared the distribution of an indicator with wellknown relationship with the socio-economic level such as low birth weight, using both the busi and the municipal districts as analysis units. the data o ... | 2007 | 2045222 |
| fumonisin mycotoxins and equine leukoencephalomalacia. | 1991 | 2045319 | |
| new advances in anesthesia. | pharmacologic advances in anesthesia over the last decade have focused on drug safety, shorter durations of action, reversibility, and ease of administration. this is reflective of major changes in the focus of patient care from inpatient to outpatient settings as well as from available risk management data that support the investigation of these new drugs. the pharmacologic advances discussed included those drugs in current practice as well as experimental drugs yet to be released for general c ... | 2007 | 2047291 |
| epidemiologic aspects of shigellosis and other causes of dysentery in thailand. | nearly 20% of children seen in the outpatient department of children's hospital in bangkok, thailand, for diarrheal disease had bloody diarrhea. shigella species and enteroinvasive escherichia coli--isolated from 13% and 2% of children with diarrhea, respectively--were the most frequent causes of bloody diarrhea. campylobacter species and nontyphoidal salmonella species were also isolated frequently but were much less often associated with bloody diarrhea. shigella species were rarely isolated f ... | 1991 | 2047642 |
| shigellosis in vietnam: seroepidemiologic studies with use of lipopolysaccharide antigens in enzyme immunoassays. | the performance of enzyme immunoassays (eias) with use of o-antigen-containing lipopolysaccharides (lpss) extracted with phenol-water from shigella dysenteriae type 1, shigella flexneri serotypes 1a-5b, and shigella sonnei for determination of the serum antibody responses after onset of bacillary dysentery is reviewed. for the purpose of several studies, serum samples from a total of 175 vietnamese and 47 swedish patients, for whom shigella species had been isolated from fecal specimens, were ob ... | 1991 | 2047643 |
| mortality due to shigellosis: community and hospital data. | almost all fatal cases of shigellosis occur in developing countries, and data on mortality are generally compiled from three sources: investigations of epidemics caused by shigella dysenteriae type 1, surveillance of endemic diarrheal disease, and reports from hospitals. attack rates during epidemics of dysentery due to infection with s. dysenteriae type 1 have ranged from 1% to 33%, and case-fatality rates have ranged from 1% to 7%. in matlab, a rural district in bangladesh, most diarrhea-relat ... | 1991 | 2047645 |
| shiga toxin: intestinal cell receptors and pathophysiology of enterotoxic effects. | shiga toxin is enterotoxic in rabbit small bowel and binds to the microvillus membrane (mvm). the toxin exhibits specificity for glycolipids possessing a terminal gal-alpha 1----4gal disaccharide, including the neutral glycolipid gb3 in mvm. gb3, which is developmentally regulated in the rabbit small bowel, is present in very low concentration until the animals reach day 16 of life. in older animals an increase in gb3 content is paralleled by an increase in the ability of mvm to bind toxin, whic ... | 1991 | 2047654 |
| response to antimicrobial therapy for shigellosis in thailand. | shigella species have been one of the most common causes of acute diarrhea in bangkok, thailand. the incidence of shigellosis increased steadily from 1984 to 1988. the majority of shigella species isolated from specimens from patients with acute diarrhea in bangkok in 1988 were resistant to both ampicillin and trimethoprim-sulfamethoxazole (tmp-smz). shigella flexneri was the most commonly isolated organism and had the highest rate of resistance to ampicillin, chloramphenicol, tmp-smz, and tetra ... | 1991 | 2047660 |
| an auxotrophic live oral shigella flexneri vaccine: development and testing. | through transduction, a wild-type strain of shigella flexneri serotype y (sfl1) was rendered auxotrophic and dependent on aromatic metabolites that are not available in mammalian tissues. monkeys that were orally vaccinated with 10(11) bacteria of the transductant strain sfl114 remained healthy when challenged with 10(11) bacteria of wild-type strains of s. flexneri serotypes y, 1b, and 2a. the safety and immunogenicity of sfl114 were next studied in volunteers who were given either 10(9) or 10( ... | 1991 | 2047663 |
| nomenclature of veins in the lower extremity. | 2007 | 2048529 | |
| prospective study of systemic and mucosal immune responses in dysenteric patients to specific shigella invasion plasmid antigens and lipopolysaccharides. | shigellosis is a major cause of infant morbidity and mortality in developing countries. to find immunological correlates of specific protection against shigellosis, we examined chronological samples of sera, stool extracts, duodenal aspirates, and saliva samples from 39 adults and 22 children with shigellosis from peru for the presence of specific antibody to invasion plasmid antigens (ipa) common to all virulent shigella strains, by using both a whole-organism enzyme-linked immunosorbent assay ... | 1991 | 2050402 |
| [antibiotic therapy of acute dysentery in children with immunologic deficiency conditions]. | one hundred children with acute sonnei and flexneri dysentery were followed up with respect to the infection process and main immunity indices. in 32 children the immunity indices were physiological (group 1) and in 68 children secondary immune deficiency was observed (group 2). the children were treated with aminoglycoside antibiotics and prodigiozan and it was stated that the time of recovery in the children with immune deficiency was longer by 5.2 days as compared to that in the children with ... | 1991 | 2053823 |
| site-specific recombinase genes in three shigella subgroups and nucleotide sequences of a pinb gene and an invertible b segment from shigella boydii. | inversional switching systems in procaryotes are composed of an invertible dna segment and a site-specific recombinase gene adjacent to or contained in the segment. four related but functionally distinct systems have previously been characterized in detail: the salmonella typhimurium h segment-hin gene (h-hin), phage mu g-gin, phage p1 c-cin, and escherichia coli e14 p-pin. in this article we report the isolation and characterization of three new recombinase genes: pinb, pind, and defective pinf ... | 1991 | 2061288 |
| [postoperative invagination in children. apropos of 4 cases]. | 2007 | 2063484 | |
| an analysis of maximum mandibular movements, craniofacial relationships and temporomandibular joint awareness in children. | this paper evaluates the relationship between maximum mandibular vertical opening and the following variables: chronological age, craniomandibular relationships, and temporomandibular joint awareness in children. the range of mandibular movement was evaluated in 189 children between the ages of 4 and 14 years, using the method of agerberg. measurements were found to be accurate and reliable only in the vertical plane. cephalometric tracings were made on 131 of the subjects. significant relations ... | 2007 | 2064068 |
| indigent health care in emergency medicine: an academic perspective. | 2007 | 2064102 | |
| immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. cellular, mediator, and permeability changes. | asthma may represent the clinical manifestations of a unique form of chronic airway inflammation and is often associated with allergy. to better define the components of allergic inflammation in the lung, fluids obtained by bronchoalveolar lavage (bal) were examined for cells, inflammatory mediators, and markers of airway permeability 5 min and 19 h following instillation of ragweed antigen directly into an airway segment of allergic asthmatic subjects. the 5-min response to antigen challenge (n ... | 2007 | 2064141 |
| the placenta in the context of history and modern medical practice. | this is a brief summary of the development of our understanding of the anatomy and physiology of the human placenta. the article also traces the origin of some of the commonly used terminology that pertains to the placenta, and it makes reference to the major discoveries made in the understanding of human placentation. the legal implications for the current need of placental examination are traced and recommendations are made for future studies that might be conducted. finally, questions are rai ... | 1991 | 2064523 |
| [a report of surveillance on acute diarrhoeal diseases in wuwei prefecture from 1987 to 1988]. | surveillance on acute diarrhoeal diseases in jinta county, wuwei city for two successive years from january 1987 to december 1988 showed that the annual average incidence of diarrhoeal diseases was 0.079-0.124. the total detection rate of the etiologic agent was 58.95%. bacterial infection was predominant. ten species of pathogenic bacteria were detected, of which shigella remained the prevalent bacteria among which flexneri appeared as the predominant species after a decline for several years s ... | 1991 | 2065350 |
| how did anne help? | 1971 | 2072260 | |
| [pheochromocytoma diagnosed during quinapril therapy]. | a hypertensive diabetic woman, who was resistant to any pharmacological therapy, underwent to check for secondary hypertension. the treatment with the particularly active ace inhibitor quinapril failed but it suggested a procedure for a fast differential diagnosis of disease. | 2007 | 2074938 |
| nonsquamous tumors of the head and neck in the geriatric population. | thyroid tumors, salivary gland tumors, and non-hodgkin's lymphoma are described. psychosocial issues involving the geriatric patient are discussed. case reports of a number of geriatric tumor patients are included. | 2007 | 2074986 |