Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [on the inhibition of lambda phage production in nutrient broth]. | 1966 | 4229809 | |
| purification and properties of the gamma-protein specified by bacteriophage lambda: an inhibitor of the host recbc recombination enzyme. | previous experiments have indicated that the gam gene of bacteriophage lambda is responsible for an inhibition of the recbc dnase-an enzyme that is essential for the major host pathway of genetic recombination. we report here experiments that define the inhibitor as the protein product of the gam gene ("gamma-protein") and that characterize the inhibition reaction with highly purified preparations of gamma-protein and recbc dnase. genetic characterization was performed with partially purified fr ... | 1973 | 4275917 |
| mapping the 5'-terminal nucleotides of the dna of bacteriophage lambda and related phages. | 1967 | 4292665 | |
| structure and base sequence in the cohesive ends of bacteriophage lambda dna. | 1968 | 4299833 | |
| isolation and base composition of sites on lambda phage dna which bind with rna polymerase of escherichia coli. | 1969 | 4306141 | |
| nucleotide sequence analysis of dna. i. partial sequence of the cohesive ends of bacteriophage lambda and 186 dna. | 1970 | 4321727 | |
| deletion mutants of bacteriophage lambda. i. isolation and initial characterization. | 1971 | 4323931 | |
| genetic expression in bacteriophage lambda. iv. effects of p2 prophage on lambda inhibition of host synthesis and lambda gene expression. | 1971 | 4331731 | |
| purification and base composition analysis of phage lambda early promoters. | rna-polymerase of escherichia coli was allowed to bind to dna of phage lambda in the absence of precursors. the resulting complex was excised by nuclease digestion and the protected dna was recovered by phenol-extraction and ethanol precipitation. acrylamide gel electrophoresis of protected dna fragments reveals the existence of two distinct oligonucleotide peaks corresponding, respectively, to 45-52 and 7-10 nucleotide residues along with species of intermediate sizes. peak i molecules have two ... | 1971 | 4332016 |
| establishment of repression by lambdoid phage in catabolite activator protein and adenylate cyclase mutants of escherichia coli. | lambdoid phages form clear plaques and show reduced ability to establish immunity in strains of escherichia coli that lack adenylate cyclase or catabolite activator protein. the absence of the activator protein or cyclic amp reduces the frequency of lysogenization, but does not prevent steady-state repressor synthesis of a lysogen. lambda phage mutants able to form turbid plaques on strains that lack catabolite activator protein or adenylate cyclase have been isolated and analyzed. | 1972 | 4333980 |
| requirement of adenosine 3',5'-cyclic phosphate for formation of the phage lambda receptor in escherichia coli. | adenosine 3',5'-cyclic phosphate is indispensable for formation of the phage lambda receptor in escherichia coli k-12. | 1972 | 4334765 |
| the role of adenosine 3',5'-cyclic monophosphate in the growth of bacteriophage lambda. | 1972 | 4340810 | |
| biochemical method for inserting new genetic information into dna of simian virus 40: circular sv40 dna molecules containing lambda phage genes and the galactose operon of escherichia coli. | we have developed methods for covalently joining duplex dna molecules to one another and have used these techniques to construct circular dimers of sv40 dna and to insert a dna segment containing lambda phage genes and the galactose operon of e. coli into sv40 dna. the method involves: (a) converting circular sv40 dna to a linear form, (b) adding single-stranded homodeoxypolymeric extensions of defined composition and length to the 3' ends of one of the dna strands with the enzyme terminal deoxy ... | 1972 | 4342968 |
| synthesis of bacteriophage lambda proteins in vitro. | 1972 | 4343946 | |
| dna nucleotide sequence restricted by the ri endonuclease. | the sequence of dna base pairs adjacent to the phosphodiester bonds cleaved by the ri restriction endonuclease in unmodified dna from coliphage lambda has been determined. the 5'-terminal nucleotide labeled with (32)p and oligonucleotides up to the heptamer were analyzed from a pancreatic dnase digest. the following sequence of nucleotides adjacent to the ri break made in lambda dna was deduced from these data and from the 3'-dinucleotide sequence and nearest-neighbor analysis obtained from repa ... | 1972 | 4343974 |
| ultraviolet-sensitive mutator strain of escherichia coli k-12. | an ultraviolet (uv)-sensitive mutator gene, mutu, was identified in escherichia coli k-12. the mutation mutu4 is very close to uvrd, between mete and ilv, on the e. coli chromosome. it was recessive as a mutator and as a uv-sensitive mutation. the frequency of reversion of trpa46 on an f episome was increased by mutu4 on the chromosome. the mutator gene did not increase mutation frequencies in virulent phages or in lytically grown phage lambda. the mutu4 mutation predominantly induced transition ... | 1973 | 4345920 |
| in vitro repression of the transcription of gas operon by purified gal repressor. | we have studied the in vitro repression of gal mrna synthesis by the gal repressor from escherichia coli. by use of a four-step purification procedure involving chromatography on phosphocellulose, deae-cellulose, and an affinity resin, the gal repressor has been purified about 1600-fold from a crude cell extract. the purification was aided by use of a cell extract made after prophage induction of cells lysogenic for bacteriophage lambda that carries the gal repressor gene (galr). the highly puri ... | 1973 | 4346883 |
| genetic and biochemical investigation of the escherichia coli mutant hfl-1 which is lysogenized at high frequency by bacteriophage lambda. | the escherichia coli mutant hfl-1 is lysogenized at very high frequency by bacteriophage lambda. the normal requirement for the lambdaciii gene product in the establishment of repression is not observed in hfl-1 strains. these phenotypic characteristics are specified by a single locus at 82.5 min on the e. coli map in extremely close proximity to the pura gene, cotransduction frequencies ranging from 97 to 100% depending on the particular pura marker used. the lactose operon is shown to function ... | 1973 | 4352176 |
| nucleotide sequence analysis with polynucleotide kinase and nucleotide "mapping" methods. 5'-terminal sequences of deoxyribonucleic acid from bacteriophages lambda and 424. | the polynucleotide kinase reaction was used in analyses of complex mixtures of oligodeoxynucleotides which were fractionated by various two-dimensional nucleotide ;mapping' procedures. parallel ionophoretic analyses on deae-cellulose paper, ph2, and ae-cellulose paper, ph3.5, of venom phosphodiesterase partial digests of 5'-terminally labelled oligonucleotides enabled the sequence of the nucleotides to be deduced uniquely. a ;diagonal ionophoresis' method has been used with mixtures of nucleotid ... | 1973 | 4352720 |
| isolation of a mutant of escherichia coli defective in cytosine-specific deoxyribonucleic acid methylase activity and in partial protection of bacteriophage lambda against restriction by cells containing the n-3 drug-resistance factor. | a mutant (designated mec(-)) of escherichia coli f(+) 100 endo i(-)su(+) r(k) (-)m(k) (+) has been isolated which is defective in cytosine-specific deoxyribonucleic acid (dna) methylase activity. the dna of this mutant, as well as the dna of phages lambda and fd propagated in it, is virtually devoid of 5-methyl-cytosine (mec); in contrast, the mutation has no significant effect on the level of n(6)-methyladenine in dna. phage lambda grown on the mec(-) mutant is more strongly restricted by n-3-c ... | 1973 | 4353870 |
| establishment of repression by bacteriophage lambda: lack of a direct regulatory effect of cyclic amp. | 1973 | 4355115 | |
| nucleotide sequence analysis of dna. xii. the chemical synthesis and sequence analysis of a dodecadeoxynucleotide which binds to the endolysin gene of bacteriophage lambda. | 1973 | 4358929 | |
| the roles of the lambda c3 gene and the escherichia coli catabolite gene activation system in the establishment of lysogeny by bacteriophage lambda. | maximum lysogenization of e. coli by bacteriophage lambda requires both the lambdaciii gene function and the host catabolite gene activation system mediated by adenosine 3':5'-cyclic monophosphate. whereas considerable lysogenization occurs in the presence of either system alone, lysogenization is absolutely prevented in the absence of both systems. neither system is, however, required for efficient lysogenization when the host bears an hfl(-) mutation. it is argued that the normal function of t ... | 1974 | 4362632 |
| threonine locus of escherichia coli k-12: genetic structure and evidence for an operon. | three genes, thra, thrb, and thrc, were previously defined and localized in the threonine locus of escherichia coli k-12. thra, thrb, and thrc specify the enzymes aspartokinase i-homoserine dehydrogenase i, homoserine kinase, and threonine synthetase, respectively. a complementation analysis of the threonine cluster using derivatives of a lambda phage carrying the threonine genes (lambdadthr(c)) demonstrates that: (i) thrb and thrc each consist of a single cistron; and (ii) thra is composed of t ... | 1974 | 4364333 |
| environmental mutagen testing in escherichia coli and phage lambda. | 1974 | 4368684 | |
| effects of dimethylsulfoxide on the e. coli gal operon and on bacteriophage lambda in vivo. | 1974 | 4369966 | |
| mutants of the n-3 r-factor conditionally defective in hspii modification and deoxyribonucleic acid-cytosine methylase activity. | the n-3 drug resistance (r) factor specifies a deoxyribonucleic acid (dna)-cytosine methylase and a dna restriction-modification (hspii) system. we have isolated three independent mutants that are conditionally defective in their ability to modify bacteriophage lambda and to methylate dna-cytosine residues. the ratio of 5-methylcytosine to n(6)-methyladenine in bacterial dna and in the dna of phages lambda and fd was determined after labeling with [methyl-(3)h]methionine at various growth temper ... | 1974 | 4371329 |
| [study of the antiviral activity of phage lambda and t2 lysates]. | 1974 | 4375922 | |
| role of host rna polymerase for lambda phage development. | 1969 | 4390186 | |
| functional abnormality of lambda phage particles from complemented fii-mutant lysates. | 1974 | 4413519 | |
| physical mapping of the trp endpoint in the n-tl segment of phage lambda trpe-a. | 1974 | 4415067 | |
| protein cleavage in bacteriophage lambda tail assembly. | 1974 | 4415352 | |
| rec-mediated recombinational hot spot activity in bacteriophage lambda. i. hot spot activity associated with spi-deletions and bio substitutions. | in order to survey the distribution along the bacteriophage lambda chromosome of rec-mediated recombination events, crosses are performed using conditions which block essentially all dna synthesis. one parent is density-labeled and carries a genetic marker in the left terminal lambda gene (a), while the other parent is unlabeled and carries a genetic marker in the right terminal lambda gene (r). both parents are deleted for the lambda recombination genes int and red, together with other recombin ... | 1974 | 4415484 |
| rec-mediated recombinational hot spot activity in bacteriophage lambda. ii. a mutation which causes hot spot activity. | crosses have been performed which identify phage mutants (chi) which cause recombinational hot spot activity in lambda. the hot spot activity is found in crosses of red(-) gam(-) chi(-) strains in rec(+) hosts; in the crosses reported here, both the chi(-) mutations and the hot spot are located near the right end of the chromosome. the hot spot occurs in standard crosses as well as under conditions which block dna synthesis, and is dependent on a functional host recb gene.-the chi mutation is sh ... | 1974 | 4415485 |
| substitution mutation in bacteriophage lambda with new specificity for late gene expression. | 1974 | 4415976 | |
| the distribution of crossovers along unreplicated lambda bacteriophage chromosomes. | the distribution of crossovers along unreplicated chromosomes of bacteriophage lambda has been examined by determining the density distributions and genotypes of particles in the progenies of crosses of density-labeled by ordinary parents in the presence of genetic blocks to replication. the red and rec systems combined produce crossovers primarily near the ends (especially the right end) of the chromosome. removal of the generalized lambda recombination functions by red and gam mutations result ... | 1974 | 4416166 |
| structure of isometric viruses containing nonidentical polypeptide chains. | the theory of caspar and klug (1962) for the structure of isometric viruses has been generalized to the case in which the identical repeating unit is composed of n nonidentical polypeptide chains. this modified theory accounts for the structure of picornaviruses, the lambda phage head, cowpea mosaic virus, and phix174, while at the same time conserving the principle of having identical subunits in identical environments. furthermore, the modified theory suggests amending the triangulation number ... | 1974 | 4418754 |
| connection of the right-hand terminus of dna to the proximal end of the tail in bacteriophage lambda. | 1974 | 4419247 | |
| diversity of regulation of genetic transcription. ii. specific relaxation of polarity in read-through transcription of the translocated trp operon in bacteriophage lambda trp. | 1974 | 4427375 | |
| [verification of the mutagenicity of phage lambda dna for rat somatic cells]. | 1974 | 4432297 | |
| deletions and insertions in the immunity region of coliphage lambda: revised measurement of the promoter-startpoint distance. | 1974 | 4432374 | |
| the effect of chloramphenicol and rifampicin on the "nicking" and "membrane attachment" of bacteriophage lambda dna. | 1974 | 4432375 | |
| a regulator protein for the length determination of bacteriophage lambda tail. | 1974 | 4437177 | |
| phage lambda dna packaging, in vitro. | 1974 | 4437178 | |
| processing and assembly of the head of bacteriophage lambda. | 1974 | 4437179 | |
| protein fusion during the assembly of phage lambda heads. | 1974 | 4437180 | |
| extent and location of dna synthesis associated with a class of rec-mediated recombinants of bacteriophage lambda. | 1974 | 4449124 | |
| comments on the arrangement of the morphogenetic genes of bacteriophage lambda. | 1974 | 4453012 | |
| the rolling-circle replicative structure of a bacteriophage lambda dna. | 1974 | 4455240 | |
| ultraviolet-induced mutation of bacteriophage lambda. induction by conjugation with ultraviolet irradiated donor cells. | 1974 | 4457753 | |
| proceedings: maturation of phage lambda dna: dependence on replication and recombination. | 1974 | 4461541 | |
| physical mapping of the att-n region of coliphage lambda: apparent oversaturation of coding capacity in the gam-ral segment. | 1974 | 4466498 | |
| [formal analysis of genetic regulation circuits: control of immunity in bacteriophage lambda]. | 1974 | 4466499 | |
| locations and amounts of major structural proteins in bacteriophage lambda. | 1974 | 4476800 | |
| topology of dna and n gene expression in coliphage lambda. | 1972 | 4503845 | |
| distance from a promoter mutation to an rna synthesis startpoint on bacteriophage lambda dna. | 1972 | 4504486 | |
| bidirectional transcription and the regulation of phage lambda repressor synthesis. | there are two promoters for transcription of gene ci in phage lambda, the gene that codes for phage repressor. the promoters, called pre and prm, are located on the distal (pre) and proximal (prm) sides of gene cro, which itself is adjacent to ci. since ci and cro are transcribed in opposite directions, ci transcription initiating at pre gives rise to an antisense transcript of cro, while ci transcription initiating at prm does not. pre, active after infection of a sensitive cell, is stimulated ... | 1972 | 4508309 |
| an enhancing role for dna synthesis in formation of bacteriophage lambda recombinants. | recombination in some intervals of the map of phage lambda is associated with more dna synthesis than in other intervals. blockage of dna synthesis by high temperature in a host temperature-sensitive for dna synthesis results in the relative reduction of recombinant frequencies in those regions having the larger amounts of recombination-associated synthesis. reduction of dna synthesis at normal temperatures by a combination of the bacterial mutation and a mutation in one of the phage genes requi ... | 1972 | 4509320 |
| positive control of endolysin synthesis in vitro by the gene n protein of phage lambda. | positive control in vitro by gene n protein of bacteriophage lambda was demonstrated. lambda dna was used to direct in vitro synthesis of lambda endolysin in a cell-free protein-synthesizing preparation derived from escherichia coli. the endolysin synthesis depends on the concomitant in vitro synthesis of lambda gene n protein. when lambda n(-) dna was used to direct the cell-free preparation, endolysin was made only if extract was added from cells in which a lambda prophage had been induced. th ... | 1972 | 4509321 |
| in vitro assembly of bacteriophage lambda heads. | the assembly of plaque-forming particles in cell-free extracts of induced lambda lysogens was observed two ways. (i) dna isolated from a lambda-related phage, 434 for example, is added to an extract of an induced lambda lysogen, and plaque-formers with the genotype of the added dna are detected. (ii) one extract from an induced lambda lysogen that carries an amber mutation in one of the head genes (a, b, c, d, or e) is mixed with one carrying an amber mutation in a different head gene; an increa ... | 1973 | 4509659 |
| multiple repressor binding at the operators in bacteriophage lambda. | short dna duplexes are protected when lambda dna is digested with nuclease in the presence of lambda repressor. as the ratio of repressor to operator is increased, six successively larger fragments are recovered, ranging in size from 35 to 100 base pairs, each of which binds repressor. study of these fragments indicates that, at each of the two lambda operators (o(l) and o(r)), repressor first binds to a unique site (not necessarily terminal), and that five additional sites are then filled in li ... | 1973 | 4514322 |
| regulation by n gene protein of phage lambda of anthranilate synthetase synthesis in vitro. | the n protein of bacteriophage lambda is a positive regulator of early lambda gene expression. in a lambdatrp transducing phage, lambdatrp46nam, the synthesis of trp enzymes in vivo is also dependent on the presence of active n protein. the dna of this phage has been used in a protein-synthesizing system in vitro to develop a biochemical assay for the activity of the n protein. from the following observations it appears that it is the n protein itself that stimulates trp enzyme synthesis in vitr ... | 1973 | 4515605 |
| the 3'-terminal nucleotide sequences of bacteriophage lambda dna. | analyses of radioactive oligonucleotides in endonuclease digests of 3'-terminally labeled lambda dna revealed the 3' terminal sequence -gttacg for the l strand and -acccgcg for the r strand. these sequences, together with those previously known for the 5' cohesive ends, provide a total of 25 known base-pairs in the vicinity of the termini. when the cohesive ends are paired, the sequence between the nicks can be bisected by a 2-fold rotational axis of symmetry. five of the first eight base-pairs, ... | 1973 | 4515613 |
| isolation of the operators of phage lambda. | 1973 | 4515906 | |
| genetic mapping of the inversion loop in bacteriophage mu dna. | an inversion loop seen in heteroduplex mapping of the dna of mature mu phage induced from a lysogen is observed also in defective lambda phage carrying one end of mu. 14% of the dna of mu, including this region, designated the g loop, is shown to be to the right of all known genes in the prophage map. the inhomogeneous ends of mu are observed as a separate phenomenon and appear in all mutants investigated. the reca and recbc functions of the host are not needed for the inversion responsible for ... | 1973 | 4516210 |
| alignment of two dna helices: a model for recognition of dna base sequences by the termini-generating enzymes of phage lambda, 186, and p2. | based on the 3'- and 5'-terminal sequences of dna of phage lambda, p2, and 186, a model is proposed for recognition of dna sequences by enzymes responsible for generation of cohesive ends. two copies of the cohered ends, either on separate molecules or on a concatemer, are aligned with their helical axes parallel but running in opposite directions. the nicking system is dimeric, with each of the two monomers carrying identical sequence-recognition sites. two pairs of nicks are introduced into th ... | 1973 | 4517677 |
| int-constitutive mutants of bacteriophage lambda. | the constitutive production of small amounts of trpb enzyme in an escherichia coli strain carrying lambdaci857 prophage within the trpc gene has been examined in derivatives of this strain from which portions of the prophage have been deleted. enzyme production requires a site (p(i)) within the prophage close to the left prophage end. selection for mutants of this lysogen that grow on low concentrations of indole yielded two types of mutations within the prophage: (a) v2-type, in which all phage ... | 1974 | 4521054 |
| protein fusion: a novel reaction in bacteriophage lambda head assembly. | parts of two phage-coded head proteins, pe and pc, become fused during bacteriophage lambda head assembly. pe is the main structural component of lambda heads and pc is a minor head protein that is not found as such in mature heads. the bond joining the two proteins appears to be covalent and is not a disulfide bond. only a specific subset of the sequences of each protein is found in the fusion products, and these sequences are found in the products in equimolar amounts. two nearly identical fus ... | 1974 | 4524648 |
| on the molecular basis of high negative interference. | two models designed to account for high negative interference phenomena have been examined. one proposal suggests that many recombination events are the result of insertion of a small single-stranded segment of dna into a recipient molecule. an alternative explanation for the clustering of genetic exchanges is reduction to homozygosity of genetically heterozygous sites appearing within heteroduplex overlap regions. these proposals have been examined in phage lambda by analyzing the structure of ... | 1974 | 4524657 |
| synthesis of bacteriophage lambda dna in vitro: requirement for o and p gene products. | we have developed a cell-free system to study bacteriophage lambda dna replication. maximal dna synthesis in vitro requires the four deoxynucleoside triphosphates, atp, and exogenous lambda dna. dna synthesis requires the products of the phage o and p genes but is not inhibited by lambda repressor. the kinetics of synthesis is linear for 10-15 min; however, the product of synthesis amounts to only 0.5-1% of the added template dna. as judged by isopycnic analysis, extensive regions of the templat ... | 1974 | 4525790 |
| in vitro genetic recombination of bacteriophage lambda. | dna of bacteriophage lambda recombines in a cell-free extract prepared from an induced escherichia coli lysogen of bacteriophage lambda. the assay for recombination in vitro takes advantage of the ability of such an extract to package lambda dna and to assemble complete phage particles. for example, when lambda dna that has been extracted from phage with the immunity of 434 is added to an extract, infectious lambda imm 434 particles are produced. the precursor dna molecule in this packaging reac ... | 1974 | 4526306 |
| bacteriophage lambda having ecori endonuclease sites only in the nonessential region of the genome. | a derivative of lambda b221 that has lost by mutation all ecori restriction sites has been isolated by alternative growth on restrictive and nonrestrictive strains. it has an efficiency of plating equal to 1 on the restrictive strain. genetic cross of this bacteriophage with lambda plac5 imm21 gave rise to recombinants of intermediate restricting ratios. the analysis of the ecori endonuclease-cleaved dna by polyacrylamide gel electrophoresis, compared with the genetic results, has permitted iden ... | 1974 | 4530273 |
| control elements in the dna of bacteriophage lambda. | 1974 | 4545512 | |
| separation and analysis of promoter sites in bacteriophage lambda dna by specific endonucleases. | 1974 | 4546908 | |
| letter: the yield of single-strand breaks in the dna of bacteriophage lambda irradiated extra- and intracellularly with gamma-rays in oxic and anoxic conditions. | 1974 | 4548053 | |
| growth of bacteriophage lambda in phospholipases a-less mutants. | 1972 | 4551923 | |
| plasmid formation from bacteriophage lambda as a result of interference by resident plasmid lambda dv. | 1972 | 4551991 | |
| lambda phage transcription in human fibroblasts. | 1972 | 4551993 | |
| a mutation in escherichia coli enhancing the uv-mutability of phage lambda but not of its infectious dna in a spheroplast assay. | 1972 | 4552500 | |
| plasmid formation from bacteriophage lambda in escherichia coli. | 1972 | 4552709 | |
| studies on the dna photoreactivating enzyme from escherichia coli. i. transduction of the phr gene by bacteriophage lambda. | 1972 | 4552790 | |
| kinetics of membrane association by bacteriophage lambda dna after repressor inactivation. | 1972 | 4553104 | |
| large-scale production of lambda bacteriophage and purified lambda deoxyribonucleic acid. | large amounts of a heat-inducible phage lambda mutant (lambdaci857) may be obtained under standardized conditions. the phage is harvested by simple polyethylene glycol (c 6000) precipitation and purified by cscl density gradient banding. deoxyribonucleic acid (dna) is extracted by cold phenol and purified by sucrose density gradient sedimentation to yield a homogenous population of unbroken lambda dna molecules. | 1972 | 4553145 |
| studies on lysogeny in escherichia coli with bacteriophage lambda. physical observation of the insertion process. | 1972 | 4553260 | |
| comparisons of the distribution of nucleotides and common sequences in deoxyribonucleic acid from selected bacteriophages. | results from comparisons of deoxyribonucleic acid (dna) from several classes of bacteriophages suggest that most phage chromosomes contain either a homogeneous distribution of nucleotides or are made up of a few, rather large segments of different quanine plus cytosine (g + c) contents which are internally homogeneous. among those temperate phages tested, most contained segmented dna. comparisons of sequence similarities among segments from lambdoid phage dna species revealed the following order ... | 1972 | 4553679 |
| effects of the rec and exr mutations of escherichia coli on uv reactivation of bacteriophage lambda damaged by different agents. | 1972 | 4555297 | |
| uv reactivation of phage lambda in a pola mutant of e. coli. | 1972 | 4555301 | |
| lytic replication of coliphage lambda in salmonella typhosa hybrids. | hybrids between escherichia coli k-12 and salmonella typhosa which conserved a continuous k-12 chromosomal diploid segment extending from pro through ara to the stra locus were sensitive to plaque formation by wild-type lambda. these partially diploid s. typhosa hybrids could be lysogenized with lambda and subsequently induced to produce infectious phage particles. when the k-12 genes were segregated from a lysogenic s. typhosa hybrid, phage-productive ability was no longer detectable due to los ... | 1972 | 4555401 |
| the morphogenesis of bacteriophage lambda. iv. identification of gene products and control of the expression of the morphogenetic information. | 1972 | 4555611 | |
| host specificity of dna produced by escherichia coli. xvi. phage lambda dna carries a single site of affinity for a-specific restriction and modification. | 1972 | 4555674 | |
| inactivation kinetics of lambda phage repressors in a mutant of e. coli temperature sensitive in dna replication. | 1972 | 4555676 | |
| gene regulation in n mutants of bacteriophage lambda. | mutants (n(-)nin) of bacteriophage lambda in which the n gene product is not required for growth on wild-type escherichia coli do not plate on reca bacterial mutants. secondary mutants, selected for growth on reca, lie within the immunity region to the right of gene ci and appear identical to the cro mutants of eisen et al. in an n(+) phage, a cro mutation causes enhanced and prolonged production of lambda exonuclease. n(-)cro phages make no detectable exonuclease, but show an increased rate of ... | 1972 | 4556510 |
| rna synthesis startpoints in bacteriophage lambda: are the promoter and operator transcribed? | 1972 | 4556643 | |
| induction of an endonuclease by some substitution and deletion variants of phage lambda. | 1972 | 4556928 | |
| substrate specificity of the three endonucleases isolated from phage lambda c 1 -infected escherichia coli. | 1972 | 4557025 | |
| recombination in bacteriophage lambda dna half molecules. | 1972 | 4557198 | |
| isolation of plaque-forming, galactose-transducing strains of phage lambda. | plaque-forming, galactose-transducing lambda strains have been isolated from lysogens in which bacterial genes have been removed from between the galactose operon and the prophage by deletion mutation.-a second class has been isolated starting with a lysogenic strain which carries a deletion of the genes to the right of the galactose operon and part of the prophage. this strain was lysogenized with a second lambda phage to yield a lysogen from which galactose-transducing, plaque-forming phages w ... | 1972 | 4558323 |
| on some genetic aspects of phage lambda resistance in e. coli k12. | most mutations rendering e. coli k12 resistant to phage lambda, map in two genetic regions mala and malb.-the malb region contains a gene lamb specifically involved in the lambda receptor synthesis. twenty-one independent lamb mutations studied by complementation belonged to a single cistron. this makes it very likely that lamb is monocistronic. among the lamb mutants some are still sensitive to a host range mutant of phage lambda. mutations mapping in a proximal gene essential for maltose metab ... | 1972 | 4558324 |
| maturation and recombination of bacteriophage lambda dna molecules in the absence of dna duplication. | 1972 | 4559112 | |
| a reanalysis of red-mediated reciprocal recombination in bacteriophage lambda. | 1972 | 4559691 |