Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| treatment strategies for postoperative propionibacterium acnes endophthalmitis. | propionibacterium acnes endophthalmitis after cataract extraction and posterior chamber intraocular lens (iol) implantation is characterized by a chronic indolent course, frequently associated with recurrence after standard endophthalmitis treatment. this study was designed to evaluate the efficacy of various therapeutic methods in the treatment of primary and recurrent episodes of postoperative p. acnes endophthalmitis. | 1999 | 10599678 |
| [oral treatment of acne. agence française de securité sanitaire des produits de santé]. | 1999 | 10605476 | |
| [apropos of recommendations concerning oral treatment of acne. an interview with the president s. belaich. interview by hélne allouch]. | 1999 | 10605477 | |
| hepatic granuloma due to propionibacterium acnes in a patient with acute myelogenous leukemia. | 2000 | 10619766 | |
| propionibacterium acnes as the cause of endocarditis in a liver transplant recipient. | 2000 | 10619770 | |
| optimizing breast pocket irrigation: an in vitro study and clinical implications. | subclinical infections have been implicated in the etiology of capsular contracture. intraoperatively, breast pocket irrigation with povidone-iodine or other antibiotic solutions has been popularized; however, detrimental effects on wound healing for these agents have been reported and their efficacy against common organisms found around breast implants has not been studied. the purpose of this study was to compare the in vitro efficacy of serial dilutions of povidone-iodine and two double antib ... | 2000 | 10627003 |
| metronidazole, its bioactive metabolites and acne. | metronidazole's activity has been established in both acneiform rosacea and acne vulgaris. recent research indicating that the breakdown products of several antibiotics, including metronidazole, may have considerably greater activity than the parent compound, prompted a re-examination of the susceptibility of propionibacterium acnes, the organism involved in the fundamental pathogenesis of acne vulgaris. although the organism was marginally more sensitive to the hydroxy derivative, mic levels we ... | 1999 | 10640262 |
| antibacterial and antiandrogen flavonoids from sophora flavescens. | sixteen flavanones, three flavanonols, and four pterocarpans were isolated from the meoh extract of the roots of sophora flavescens. twelve of these were new compounds, including eight prenylflavanones (1-8), one prenylflavanonol (9) and three novel pterocarpane derivatives (10-12). their structures were elucidated using nmr and mass spectral methods. some of these compounds have irregular c10 prenyl moieties at c-8 of the flavanone skeleton. these compounds exhibited significant antibacterial a ... | 1999 | 10654410 |
| topical therapy for acne. | acne is a common problem in adolescents and young adults. the disorder is caused by abnormal desquamation of follicular epithelium that results in obstruction of the pilosebaceous canal. this obstruction leads to the formation of comedones, which can become inflamed because of overgrowth of propionibacterium acnes. topical retinoids such as tretinoin or adapalene are effective in many patients with comedonal acne. patients with inflammatory lesions benefit from treatment with benzoyl peroxide, a ... | 2000 | 10670502 |
| natural killer activity in mice infected with rabies virus and submitted to p. acnes (propionibacterium acnes) as immunomodulator. | the natural killer (nk) activity and lethality were evaluated in swiss mice experimentally infected with street rabies virus and submitted to immunomodulation by p. acnes (formerly corynebacterium parvum). the infected animals were sacrificed at different times and spleen non-adherent cells were obtained through ficoll-hypaque gradient and depletion of glass-adherent cells. immunosuppression was observed in rabies virus infected mice correlated with lower nk activity in clinically ill animals. h ... | 2000 | 10670698 |
| [propionibacterium acnes--pathogenetic significance in sarcoidosis?]. | 1999 | 10681204 | |
| leucocyte entry and endothelial e-selectin expression following intradermal propionibacterium acnes administration. | immune responses in porcine skin to intradermal inoculation of heat-killed propionibacterium acnes (hkpa), the major bacterial agent associated with human inflammatory acne, were studied. pigs were chosen as experimental animals because their skin is similar in structure and composition to that of man and because the use of genetically inbred pigs enables leucocytes to be transferred between animals without eliciting rejection responses. two pigs were sensitized intradermally with 10 mg of hkpa ... | 2000 | 10684686 |
| postoperative endophthalmitis caused by sequestered acinetobacter calcoaceticus. | to describe postoperative endophthalmitis caused by sequestered acinetobacter calcoaceticus. | 2000 | 10704562 |
| altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage. | although obesity-related fatty livers are vulnerable to damage from endotoxin, the mechanisms involved remain obscure. the purpose of this study was to determine if immunologic priming might be involved by determining if fatty livers resemble normal livers that have been sensitized to endotoxin damage by propionibacterium acnes infection. the latter induces interleukin (il)-12 and -18, causing a selective reduction of cd4+nk t cells, diminished il-4 production, deficient production of t-helper t ... | 2000 | 10706553 |
| safety, efficacy, and functionality of high-field strength interventional magnetic resonance imaging for neurosurgery. | interventional magnetic resonance imaging (mri) allows neurosurgeons to interactively perform surgery using mri guidance. high-field strength (1.5-t) imaging permits exceptional observation of intracranial and spinal pathological features. the development of this technology and its application to a variety of neurosurgical procedures are described. | 2000 | 10719860 |
| effects of cannabinoid receptor agonist and antagonist ligands on production of inflammatory cytokines and anti-inflammatory interleukin-10 in endotoxemic mice. | previous studies have shown that mice primed with corynebacterium parvum produce higher levels of inflammatory cytokines than unprimed mice upon challenge with lipopolysaccharide (lps). herein, we describe experiments in which two cannabinoid (cb) agonists, win 55212-2 [(r)-(+)-[2, 3-dihydro-5-methyl-3-[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]1, 4-benzoxazin-6-yl](1-naphthyl)methanone) and hu-210 [(-)-11-hydroxy-delta(8) tetrahydrocannabinol-dimethylheptyl], were examined for their effects on lps ... | 2000 | 10734163 |
| [prognosis of postoperative endophthalmitis]. | the outcome of 20 patients is summarized in a retrospective study to identify clinical findings that influence the long-term prognosis of postoperative endophthalmitis. | 2000 | 10734738 |
| [in vitro activities of levofloxacin and other antibiotics against fresh clinical isolates]. | in this study, the in vitro activity of levofloxacin (lvfx) against 1,020 fresh bacterial clinical isolates was compared with the activities of a range of ofloxacin, ciprofloxacin (cpfx), ampicillin (abpc), cefaclor, cefpodoxime, methicillin and benzylpenicillin. the clinical isolates except vibrio cholerae were collected in japan during 1998 from patients with infectious diseases. mics were determined using the agar dilution method according to the recommendations by the japan society of chemot ... | 1999 | 10746192 |
| the change in leukotrienes and lipoxins in activated mouse peritoneal macrophages. | the aim of this study was to investigate to what extent the generation of leukotrienes (lts) and lipoxins (lxs) was affected by the expression of definite levels of macrophage activation. we used a system of murine peritoneal macrophages at different states of activation consisting in resident macrophages and fcs-, thioglycollate- or corynebacterium parvum-elicited macrophages. the profile of lipoxygenase metabolites in resident macrophages was characterized by the presence of high levels of 12- ... | 2000 | 10760459 |
| effects of 50 hz electric currents and magnetic fields on the prokaryote propionibacterium acnes. | the effects of 50 hz sinusoidal electric currents and magnetic fields on the gram-positive skin bacterium propionibacterium acnes were investigated. intracellular free calcium ([ca(2+)](i)), intracellular ph (ph(i)), and cell viability were examined, based on their relevance to elf field studies and on previous studies conducted on p. acnes (uva irradiation, photosensitization using porphyrin-based sensitizers, and broad-band red light). the [ca(2+)](i) and the ph(i) were measured spectrofluorim ... | 2000 | 10797458 |
| liver-infiltrating t lymphocytes are attracted selectively by ifn-inducible protein-10. | we have demonstrated that interferon-inducible protein-10 (ip-10) is produced in hepatocytes surrounded by infiltrative mononuclear cells in chronic hepatitis. to clarify the role of ip-10 in hepatitis, we examined the chemoattractive activity of ip-10 on liver-infiltrating lymphocytes in experimental animal models of hepatitis. ip-10 was specifically induced in the livers of mice treated intravenously (i.v.) with con a, while monocyte chemotactic protein-1 (mcp-1) showed a much lower level of i ... | 2000 | 10805209 |
| cytokine regulation of liver injury and repair. | by comparing the hepatic responses to tumor necrosis factor (tnf)-alpha that occur during situations that promote liver injury (such as obesity or chronic exposure to ethanol) with those that occur after stimuli (such as partial hepatectomy) that lead to liver regeneration, it is apparent that hepatocytes are usually able to constrain noxious responses to tnf-alpha, such as the release of reactive oxygen from mitochondria. it appears that by promptly upregulating survival genes that regulate mit ... | 2000 | 10807515 |
| pathophysiological roles of interleukin-18 in inflammatory liver diseases. | innate immune response to microbes sometimes determines the nature of the following specific immune response. kupffer cells, a potent constituent of innate immunity, play a key role in developing the type 1 immune response by interleukin (il)-12 production. furthermore, kupffer cells have the potential to induce liver injury by production of il-18. propionibacterium acnes-primed lipopolysaccharide (lps)-challenged liver injury is the prototype of il-18-induced tissue injury, in which il-18 acts ... | 2000 | 10807517 |
| phototherapy and acne vulgaris. | 2000 | 10809839 | |
| the cutaneous microflora of adolescent, persistent and late-onset acne patients does not differ. | the cutaneous microbiology and antibody status to propionibacterium acnes of patients with persistent (males, n = 32; females, n = 33) and late-onset (females, n = 25) acne were compared with individuals with adolescent acne (males, n = 22; females, n = 18) and normal control volunteers (persistent acne: males, n = 26; females, n = 30; late-onset: females, n = 20). males had significantly higher grades of acne compared with females (p < 0.05). the microflora consisted in the main of propionibact ... | 2000 | 10809844 |
| granulomatous hepatitis in an immunocompromised patient diagnosed by minilaparoscopy. | 2000 | 10817195 | |
| corneal biopsy in the management of progressive microbial keratitis. | to study the indications and role of diagnostic corneal biopsy in the management of patients with progressive microbial keratitis. | 2000 | 10844046 |
| bacterial contamination of anterior chamber during iol surgery. | to study the nature and frequency of bacterial contamination during cataract surgery. | 1999 | 10858775 |
| effects of znc-2381, a new oral compound, on several hepatic injury models and on hepatocellular apoptosis in mice and rats. | the hepatoprotective effect of znc-2381 (1-(4-aminophenyl) methyl-3-(3-nitrophenyl)-1,3-dihydroimidazo[4,5-b]pyridine-2-one), a novel 2-one dihydroimidazopyridine derivative, has been evaluated in several experimental models of hepatic injury. in mice, oral znc-2381, administered at doses of 3, 10 or 30 mgkg(-1), 1 h before induction of hepatic injury with concanavalin a, dose-dependently inhibited increases in serum alanine aminotransferase (alt) activity. apoptosis of liver cells, as indicated ... | 2000 | 10864141 |
| the bacteriology of acne vulgaris and antimicrobial susceptibility of propionibacterium acnes and staphylococcus epidermidis isolated from acne lesions. | we examined the species of bacteria aerobically and anaerobically isolated from 30 acne lesions and determined antimicrobial susceptibilities of propionibacterium acnes (p. acnes) and staphylococcus epidermidis (s. epidermidis) using nine antimicrobial agents. among the bacteria isolated, s. epidermidis was most dominant. both p. acnes and s. epidermidis were isolated from half of the acne lesions. the mic of seven antimicrobials (ampicillin, erythromycin, roxithromycin, clindamycin, tetracyclin ... | 2000 | 10875198 |
| skin-specific caspase-1-transgenic mice show cutaneous apoptosis and pre-endotoxin shock condition with a high serum level of il-18. | to study the pathophysiological roles of overexpressed caspase-1 (casp1), originally designated as il-1 beta-converting enzyme, we generated transgenic mice in which human casp1 is overexpressed in their keratinocytes. the transgenic mice spontaneously developed recalcitrant dermatitis and skin ulcers, characterized by the presence of massive keratinocyte apoptosis. the skin of the mice contained the active form of human casp1 and expressed mrna for caspase-activated dnase, an effector endonucle ... | 2000 | 10878376 |
| combination azelaic acid therapy for acne vulgaris. | there is no topical antiacne medication that acts against all four of the major pathophysiologic features of acne: hyperkeratinization, sebum production, bacterial proliferation, and inflammation. topical azelaic acid cream helps both to normalize keratinization and to reduce the proliferation of propionibacterium acnes, and has proven to be effective against both noninflammatory and inflammatory lesions. the results of a recent study now demonstrate that its efficacy can be enhanced, and patien ... | 2000 | 10898830 |
| [infectious osteoarthritis due to propionibacterium acnes. two new cases]. | propionibacterium acnes is an anaerobic germ, usually found as a saprophyte of the skin and the mucosa. it may be responsible for iatrogenic or spontaneous osteoarhritis. | 2000 | 10909155 |
| alcaligenes xylosoxidans and propionibacterium acnes postoperative endophthalmitis in a pseudophakic eye. | to report a case of persistent polymicrobial postoperative endophthalmitis caused by alcaligenes xylosoxidans and propionibacterium acnes in a pseudophakic eye. a. xylosoxidans is a gram-negative bacteria resistant to most antibiotics. | 2000 | 10927000 |
| propionibacterium acnes as a cause of visually significant corneal ulcers. | to report propionibacterium acnes as a cause of vision-threatening infectious keratitis and to discuss culture isolation and antibiotic treatment. | 2000 | 10928755 |
| high-performance liquid chromatography analysis of porphyrins in propionibacterium acnes. | 2000 | 10929774 | |
| propionibacterium acnes endophthalmitis requiring intraocular lens removal after failure of medical therapy. | a 52-year-old saudi man developed intraocular inflammation 7 weeks after uneventful phacoemulsification with implantation of a silicone posterior chamber intraocular lens (iol). cultures from the aqueous and vitreous were repeatedly negative, but a temporary response to intracameral and intravitreal injection of vancomycin was noted. a series of 6 intraocular injections given over 5 days failed to resolve the inflammation. it did, however, disappear after the iol was removed. the iol provided th ... | 2000 | 10946205 |
| [effective and safe pharmacotherapy of acne vulgaris and treatment of sun-damaged skin]. | an inevitable condition for the pharmacist is a basic knowledge of dermatological changes which are prominent in acne and solar impairment of the skin to be able to recommend in a qualified manner an effective and safe treatment to the patient. however, sufferers of the more serious forms of acne should always be referred to their general practitioner, or preferentially a dermatologist. acne vulgaris is an androgen-induced disorder, but three major mechanisms for the development of the disease h ... | 2000 | 10953445 |
| vitrectomy for endophthalmitis after intraocular lens implantation. | to report the results of vitrectomy and intraocular lens (iol) removal for the treatment of endophthalmitis after iol implantation. | 2000 | 10974303 |
| nitric oxide is neither necessary nor sufficient for resolution of plasmodium chabaudi malaria in mice. | malaria is a life-threatening re-emerging disease, yet it is still not clear how bloodstage malarial parasites are killed. nitric oxide (no), which has potent anti-microbial activity, may represent an important killing mechanism. the production of no during descending plasmodium chabaudi parasitemia, a period when parasites are killed by the immune response, supports this concept. however, nos20/0 and nos30/0 mice as well as mice treated with no synthase 2 (nos2) inhibitors do not develop exacer ... | 2000 | 10975849 |
| in vitro activity of an evernimicin derivative, sch27899, against anaerobic bacteria and propionibacterium acnes. | the in vitro activity of sch27899, a novel oligosaccharide antimicrobial agent, was compared with those of representatives of six classes of antimicrobial agents (piperacillin, clarithromycin, clindamycin, vancomycin, sitafloxacin and metronidazole) against clinical isolates of anaerobic bacteria and propionibacterium acnes. against peptostreptococcus: spp. and clostridium difficile, sch27899 was the most potent (mic(90) < 0.125 mg/l) of the agents examined. besides these gram-positive anaerobes ... | 2000 | 10980176 |
| correlation between propionibacterium acnes biotypes, lipase activity and rash degree in acne patients. | we examined the possible correlation between biotypes of propionibacterium acnes, lipase activity, and rash degree in acne patients. among 5 p. acnes biotypes, p. acnes biotype 3 (b3) was the most common, followed by p. acnes biotypes 1, 2 and 4; p. acnes biotype 5 was not found. p. acnes b3 was isolated from more severe skin rashes than those of the other biotypes. production of propionic acid (pa) and butyric acid (ba) by p. acnes b3 was higher than those by the other p. acnes biotypes. as the ... | 2000 | 10989576 |
| effects of hepatocellular iron imbalance on nitric oxide and reactive oxygen intermediates production in a model of sepsis. | in mammals iron homeostasis is most important, as imbalance of iron such as iron overload may lead to severe diseases. recently, it has been shown that the iron regulatory protein-1 is partially controlled by nitric oxide and reactive oxygen intermediates, molecules frequently seen in inflammatory events. the aim of the present study was to investigate the effects of impaired iron homeostasis on the interaction of nitric oxide, and reactive oxygen intermediate formation in hepatocytes in a model ... | 2000 | 11019994 |
| increased expression of osteopontin in activated kupffer cells and hepatic macrophages during macrophage migration in propionibacterium acnes-treated rat liver. | osteopontin is an extracellular matrix component that can act as a chemokine to induce macrophage migration. the significance of osteopontin in macrophage infiltration into the liver was examined in rats given heat-killed propionibacterium acnes. in normal rats, osteopontin mrna expression in the liver was minimal, determined by quantitative-competitive reverse transcription-polymerase chain reaction (rt-pcr) assay. northern blot analysis revealed that osteopontin mrna was not expressed in kupff ... | 2000 | 11023041 |
| chemotactic cytokines (chemokines) in human hepatitis and experimental hepatitis models: which ones play the crucial role? | 2000 | 11023047 | |
| heat shock proteins and inflammatory acne vulgaris: molecular cloning, overexpression and purification of a propionibacterium acnes groel and dnak homologue. | propionibacterium acnes is associated with inflammatory acne. the genes encoding two putative mediators of inflammation, the heat shock proteins groel and dnak, were cloned from this organism and sequenced. groel and dnak encode proteins of 56.8 and 66.4 kda, respectively, which show a high degree of homology (>75% similarity) to the groel and dnak proteins of mycobacteria and streptomycetes. the promoter regions of both genes contain inverted repeat sequences believed to be involved in the tran ... | 2000 | 11024261 |
| proliferative response of peripheral blood mononuclear cells and levels of antibody to recombinant protein from propionibacterium acnes dna expression library in japanese patients with sarcoidosis. | the causes of sarcoidosis are unknown. propionibacterium acnes has been isolated from sarcoid lesions, and many genomes of p. acnes or p. granulosum have been detected in all biopsy samples tested from japanese patients with sarcoidosis. we searched for protein antigens from propionibacteria that caused immune responses in patients with sarcoidosis but not in subjects without sarcoidosis. | 2000 | 11033841 |
| red light kills bacteria via photodynamic action. | with the increase in the number of antibiotic resistant strains of microorganism, the search for alternative treatments of microbial infections becomes all the more important. we report a novel method for bacterial inactivation based on the optical excitation of the naturally occurring (endogenous) photosensitzing porphyrins by red light. in particular, the pathogenic gram-positive porphyrin producing atcc strains propionibacterium acnes, actinomyces odontolyticus and porphyromonas gingivalis we ... | 2000 | 11075959 |
| [microbiological flora cultured from peritoneal fluid of women in reproductive age]. | the aim of the study was to assess the presence of the microbes in peritoneal fluid of women in reproductive age. an investigation was performed on the group of 144 women operated laparoscopically in division of reproduction. the bacteria were cultured from 77 fluids (53.5%). the most common bacteria were: staphylococcus epidermidis (34.1%) and propionibacterium acnes (19.3%). in our group of patients 88 strains of bacteria were isolated. sensitivity to antibiotics differed in many points. this ... | 2000 | 11082969 |
| the effects of amoxicillin therapy on skin flora in infants. | in order to determine the effect of amoxicillin therapy on the perineal skin microbial flora in infants, we took quantitative bacterial and fungal cultures of perineal and sternal areas from 25 infants treated with amoxicillin (40 mg/kg/day) for 10 days. specimens were obtained prior to therapy, within 3 days of conclusion of therapy, and 14-16 days later. immediately following therapy, a decline in the number of bacterial isolates occurred on both the perineum (89 to 47) and sternum (84 to 39). ... | 2000 | 11085662 |
| biological properties associated with the enhanced lung-colonizing potential in a b16 murine melanoma line grown in a medium conditioned by syngeneic corynebacterium parvum-elicited macrophages. | a previous study by our laboratory showed that the peritoneal murine corynebacterium parnum-elicited macrophages released into their growth medium an activity which enhanced the ability of b16-f10 melanoma cells to form experimental metastases in the lung of syngeneic mice. in the present study, we used a clone of b16-f10 line (f10-m3 cells) to investigate whether the increase in lung-colonizing potential due to the pro-clonogenic activity released by c. parvum-elicited macrophages was associate ... | 1999 | 11089888 |
| relationship between propionibacterium acnes biotypes and jumi-haidoku-to. | we examined the relationship between propionibacterium acnes biotypes and jumi-haidoku-to (jht). in all the p. acnes strains tested, the production of propionic acid (pa) and butyric acid (ba) was suppressed in a medium containing 1 mg/ml jht compared with the control medium without jht. there were no significant differences in the rates of decreased pa and ba production between p. acnes biotype 3 (b3) and the other biotypes or between isolates from mild skin rash and more severe skin rash. p. a ... | 2000 | 11092266 |
| the shampoo clue: two cases of infection of a ventriculoatrial shunt. | despite the use of sophisticated tools, infections of implanted devices may be difficult to diagnose. two cases of infections of ventriculoatrial shunts, which demonstrate the eminent importance of meticulously taking history, are reported and discussed. | 2000 | 11096029 |
| a high incidence of staphylococcus aureus colonization in the external eyes of patients with atopic dermatitis. | to determine the frequency distribution of bacteria on the external surface of eyes of patients with atopic dermatitis (ad) and to investigate the relationship between the frequency of bacterial colonization and the grade of atopy or ocular diseases associated with ad. | 2000 | 11097590 |
| preventive effect of fk 506 (tacrolimus hydrate) on experimentally induced acute liver injury in rats. | the aim of the study was to investigate the effect of the immunosuppressant fk 506 (tacrolimus hydrate) on acute liver injury induced by propionibacterium acnes and lipopolysaccharide (lps). acute liver injury was induced in male wistar rats by injecting the animals with p. acnes (10 mg/rat), and administering lps (10 microg/rat) seven days later. one group was given fk 506 (1 mg/kg) 24 and 2 hr before administration of lps, and the other group was given the same dose of saline. the 24-hr surviv ... | 2000 | 11117573 |
| inherited il-12 unresponsiveness contributes to the high lps resistance of the lps(d) c57bl/10sccr mouse. | lps(d) mouse strains are characterized by the presence of a defective lps/tlr4 gene that make them refractory to the biological activity of lps. one of the mouse strains commonly used to study lps defects is the c57bl/10sccr (cr) strain. however, unlike other lps(d) strains, the cr strain also has a heavily impaired ifn-gamma response to micro-organisms. as a consequence, unlike other lps(d) mouse strains, they do not acquire a partial lps susceptibility when treated with sensitizing bacteria. b ... | 2001 | 11123338 |
| comparison of the effectiveness of some pleural sclerosing agents used for control of effusions in malignant pleural mesothelioma: a review of 117 cases. | management of malignant pleural mesothelioma (mpm) has been an important clinical issue regardless of the treatment modality employed. we aimed to investigate the efficacy of oxytetracycline (ot), corynebacterium parvum (cp), and nitrogen mustard (nm) in the management of pleural effusion associated with mpm. | 2000 | 11124644 |
| regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease. | we have studied the recruitment and roles of distinct dendritic cell (dc) precursors from the circulation into propionibacterium acnes-induced granulomas in mouse liver. during infection, f4/80(-)b220(-)cd11c(+) dc precursors appeared in the circulation, migrated into the perisinusoidal space, and matured within newly formed granulomas. recruited dcs later migrated to the portal area to interact with t cells in what we term "portal tract-associated lymphoid tissue" (palt). macrophage inflammator ... | 2001 | 11136819 |
| [azithromycin: an anti-inflammatory effect in chronic recurrent multifocal osteomyelitis? a preliminary report]. | in this preliminary communication we report our experience with azithromycin in patients with chronic recurring multifocal osteomyelitis (crmo). seven out of 13 patients, mainly teenager, showed a fast clinical improvement after they were started on azithromycin. the immediate therapeutic effect of azithromycin in patients with crmo was surprising and lead us to the hypothesis that azithromycin could have an antiphlogistic in addition to it's antibiotic effect in this disease setting. in patient ... | 2000 | 11142932 |
| chronic destructive oligoarthritis associated with propionibacterium acnes in a female patient with acne vulgaris: septic-reactive arthritis? | propionibacterium acnes is an anaerobic bacillus implicated in certain chronic arthritides. this report describes an hla-b27+ 17-year-old woman with acne vulgaris who presented with rapidly destructive arthritis in the left shoulder as well as an evolving left subclavicular adenopathy. one year later, arthritis was detected in the left knee; the inflammatory synovial fluid was sterile. growth of p acnes was observed in cultures of the shoulder synovium and lymph nodes, but polymerase chain react ... | 2000 | 11145044 |
| the role of laparoscopic biopsies in lumbar spondylodiscitis. | infection of an intervertebral disk is a serious condition. diagnosis often is elusive and difficult. it is imperative to obtain appropriate microbiological specimens before initiation of treatment. the authors describe a 51-year-old woman with lumbar spondylodiscitis that was because of infection after the placement of an epidural catheter for postoperative analgesia. a spinal magnetic resonance imaging confirmed the diagnosis, but computed tomography-guided fine needle biopsy did not provide a ... | 2000 | 11147923 |
| blockade of secondary lymphoid tissue chemokine exacerbates propionibacterium acnes-induced acute lung inflammation. | chemokine-chemokine receptor interaction plays an essential role in leukocyte/dendritic cell (dc) trafficking in inflammation and immune responses. we investigated the pathophysiological roles of secondary lymphoid tissue chemokine (slc; ccl21) and macrophage inflammatory protein-2 (mip-2) in the development of acute pulmonary inflammation induced by an intratracheal injection of propionibacterium acnes in mice. immunohistochemical studies revealed that slc was constitutively expressed in the pe ... | 2001 | 11160258 |
| the selenoorganic compound ebselen suppresses liver injury induced by propionibacterium acnes and lipopolysaccharide in rats. | ebselen (2-phenyl-1,2-benzoisoselenazol-3[2h]-one) is a selenoorganic compound containing selenium that has various pharmacological effects, including anti-inflammatory and antioxidant activity. kupffer cells, residual hepatic macrophages, play an important role in the development of liver injury by producing free radicals and cytokines. the aim of this study is to evaluate whether ebselen suppresses macrophage-associated liver injury in rats. in vivo, we examined the effects of ebselen on liver ... | 2001 | 11179515 |
| microbiology of serous otitis media in children: correlation with age and length of effusion. | the purpose of this study was to correlate the microbiology of serous otitis media in children with the duration of the condition and the patient's age. aspirates of serous ear fluids from 114 children were examined for aerobic and anaerobic bacteria. bacterial growth was noted in 47 patients (41%). aerobic organisms only were recovered in 27 aspirates (57% of the culture-positive aspirates); anaerobic bacteria only in 7 (15%); and mixed aerobic and anaerobic bacteria in 13 (28%). a total of 83 ... | 2001 | 11201816 |
| assessment of periradicular microbiota by dna-dna hybridization. | in the present study the "checkerboard" dna-dna hybridization technique was used to identify bacteria in periapical endodontic lesions of asymptomatic teeth. thirty-four patients with root-filled teeth and apical periodontitis were divided into two groups, each containing 17 patients. in group 1, a marginal incision was performed during surgery to expose the lesion, and in group 2, a submarginal incision was applied. the gingiva and mucosa were swabbed with an 0.2% chlorhexidine gluconate soluti ... | 2000 | 11202881 |
| [bacterial contamination of platelet concentrates by propionibacterium acnes]. | in this study, three incidents of platelet contamination by proprionibacterium acnes and an investigation of the transfusion process have been reported, which occurred at the nord-pas-de-calais blood center over a period of several months. p. acnes is a bacterium that is present in the cutaneous flora; it does not produce any toxin, and is rarely considered as a pathogenic agent; its occurrence is widespread, in particular in those regions that are rich in sebum (face, back, scalp), and it is ex ... | 2000 | 11204839 |
| [differential diagnosis and etiology of epitheloid cell granulomatosis of the lung]. | our knowledge on epithelioid cell granulomatosis of the lung has been extended in recent years. new entities have been added, like zirconiosis, others like tuberculosis, mycobacteriosis and sarcoidosis have gained new interest, because molecular techniques allowed new insight into their pathogenesis and a more rapid and species-specific diagnosis. experimental work in addition has added a lot of information about the network of cytokines and other inflammatory mediators responsible for granuloma ... | 2000 | 11217431 |
| correlation between microbiology and previous sinus surgery in patients with chronic maxillary sinusitis. | aspirates of 108 chronically inflamed maxillary sinuses were processed for aerobic and anaerobic bacteria. there were 295 bacterial isolates: 109 aerobic and facultative, and 186 anaerobic. the predominant aerobic isolates were staphylococcus aureus (17 isolates), alpha-hemolytic streptococci (14), pseudomonas aeruginosa (12), moraxella catarrhalis (10), and haemophilus spp (8). the predominant anaerobes were peptostreptococcus spp (61), prevotella spp (45), fusobacterium spp (15), and propionib ... | 2001 | 11219522 |
| molecular identification of bacterial 16s ribosomal rna gene in liver tissue of primary biliary cirrhosis: is propionibacterium acnes involved in granuloma formation? | the etiopathogenesis of primary biliary cirrhosis (pbc) remains speculative. epithelioid granulomas are often found in the vicinity of damaged interlobular bile ducts in pbc, raising the possibility of a reaction to microbial materials. in this study, we tried to detect and identify bacterial dna within granulomatous lesions in pbc. using liver sections from 9 patients with pbc and 13 control livers, granuloma in portal tracts, portal tracts without granuloma, and adjacent hepatic parenchyma wer ... | 2001 | 11230731 |
| [propionibacterium acnes spondylodiscitis: a case report]. | 2001 | 11234683 | |
| the development of antibiotic resistance in propionibacterium acnes. | two separate studies evaluated the ability of a combination topical gel consisting of 5% benzoyl peroxide and 1% clindamycin to reduce facial propionibacterium acnes counts in vivo and to decrease the development of resistant organisms. in the first study, the combination gel was compared with 3 topical formulations of 1% clindamycin phosphate (gel, lotion, and solution) in 80 individuals. after only 1 week of treatment, a 99.7% reduction from baseline in facial p acnes count was obtained with t ... | 2001 | 11236211 |
| potential role for a new combination topical therapy in treating mild to moderate acne vulgaris. | although a variety of established topical therapies are available to treat acne, treatment success is not always achieved with current preparations. moreover, many patients find the formulations less than fully acceptable for various reasons. a new gel that stably combines 5% benzoyl peroxide and 1% clindamycin has become available to treat mild to moderately severe inflammatory acne. there are several benefits associated with this new topical combination product: cosmetic and aesthetic acceptab ... | 2001 | 11236212 |
| are 2 combined antimicrobial mechanisms better than 1 for the treatment of acne vulgaris? clinical and antimicrobial results of a topical combination product containing 1% clindamycin and 5% benzoyl peroxide. introduction. | acne vulgaris is the most common chronic skin condition seen by dermatologists. available topical therapies include comedolytic agents such as tretinoin, adapalene, azelaic acid, tazarotene, and salicylic acid; bactericidal agents such as benzoyl peroxide; antibiotics such as clindamycin, erythromycin, and tetracycline; and anti-inflammatory agents such as sodium sulfacetamide and metronidazole. therapeutic failure with some antibiotic regimens due to the presence or development of resistant str ... | 2001 | 11236213 |
| cytokine expression in the mouse brain in response to immune activation by corynebacterium parvum. | cytokine expression in the brain has been suggested to mediate various sickness behaviors. here we report that intraperitoneal injection of a corynebacterium parvum antigen in c57bl/6 mice was followed by prolonged upregulation of cytokines in the cerebral cortex and subcortical structures in a time course that coincided with reduced spontaneous running activity. | 2001 | 11238237 |
| antibiotic sensitivity of propionibacterium acnes isolates from patients with acne vulgaris in a tertiary dermatological referral centre in singapore. | to study the minimum inhibitory concentrations (mics) of propionibacterium acnes (p. acnes) isolates to selected antibiotics from patients with acne vulgaris in singapore and determine if resistance increases with prolonged use of antibiotics. | 2001 | 11242619 |
| antibiotics in acne: time for a rethink. | 2001 | 11251550 | |
| killing of cutaneous microbial species by photodynamic therapy. | photodynamic therapy (pdt) utilizes photosensitizers and light. whereas pdt use in cancer treatment has been widely accepted, antimicrobial pdt (apdt) is still in its early stages of development. | 2001 | 11251558 |
| phenotypic and genotypic characterization of antibiotic-resistant propionibacterium acnes isolated from acne patients attending dermatology clinics in europe, the u.s.a., japan and australia. | propionibacterium acnes is the target of antimicrobial treatments for acne vulgaris. acquired resistance to erythromycin, clindamycin and tetracyclines has been reported in strains from diverse geographical loci, but the molecular basis of resistance, via mutations in genes encoding 23s and 16s rrna, respectively, has so far only been elucidated for isolates from the u.k. | 2001 | 11251569 |
| the role of laparoscopic biopsies in lumbar spondylodiscitis. | the infection of an intervertebral disk is a serious condition. the diagnosis often is elusive and difficult to make. it is imperative to have appropriate microbiologic specimens before the initiation of treatment. we report the case of a 51-year-old woman with lumbar spondylodiscitis caused by infection after the placement of an epidural catheter for postoperative analgesia. a spinal magnetic resonance imaging (mri) scan confirmed the diagnosis, but computed tomography (ct)-guided fine-needle b ... | 2000 | 11285529 |
| postoperative proprionobacterium acnes endophthalmitis. | 2001 | 11297458 | |
| postoperative proprionibacterium acnes endophthalmitis. | 2001 | 11297461 | |
| activation of clindamycin phosphate by human skin. | to investigate the relative antimicrobial activity of clindamycin phosphate (cp) and clindamycin (cly) and to examine the effect of skin homogenates on the activity of cp. | 2001 | 11309066 |
| antimicrobial effect of acidified nitrite on dermatophyte fungi, candida and bacterial skin pathogens. | nitric oxide is generated from sweat nitrite in the acidic environment of the skin surface and is thought to contribute to protection against infection. this study examined the sensitivity of trichophyton mentagrophytes, t. rubrum, candida albicans, streptococcus pyogenes, staphylococcus aureus and propionibacterium acnes to acidified nitrite. | 2001 | 11309079 |
| antigen-specific t(h)1 cells as direct effectors of propionibacterium acnes-primed lipopolysaccharide-induced hepatic injury. | t(h)1 cells are cytotoxic effector cells that utilize fas ligand (fasl) and tumor necrosis factor. the physiological roles of cytotoxic t(h)1 cells are considered to be immunoregulation by eliminating autoreactive lymphocytes or hyper-activated foreign antigen-specific lymphocytes. their pathological roles, however, remain to be clarified. to investigate whether t(h)1 cells can destroy organs, we generated a propionibacterium acnes-specific t(h)1 clone from c57bl/6 mice and tested whether the cl ... | 2001 | 11312248 |
| evaluation of an automated culture system for detecting bacterial contamination of platelets: an analysis with 15 contaminating organisms. | approximately 1 in 2000 platelet components are bacterially contaminated. the time to detection of 15 seeded organisms in platelets recovered from an automated culture system was studied. | 2001 | 11316897 |
| digital fluorescence as a parameter of propionibacterium acnes suppression needs assessment. | 2001 | 11328389 | |
| propionibacterium acnes as a cause of visually significant corneal ulcers. | 2001 | 11333339 | |
| role of monocyte chemoattractant protein-1 in propionibacterium acnes-induced pulmonary granulomatosis. | the inflammatory process in granulomatous disorders such as sarcoidosis is mainly the consequence of delayed hypersensitivity induced by causative antigens. propionibacterial dna was isolated recently by pcr from human sarcoidosis tissue. hence, we developed a model using sensitized rabbits for t cell-mediated pulmonary granulomatosis induced by propionibacterium acnes (p. acnes) and investigated the role of monocyte chemoattractant protein-1 (mcp-1) in the pathogenesis of the granuloma formatio ... | 2001 | 11340674 |
| controlled comparison of original vented aerobic fan medium with new nonvented bact/alert fa medium for culturing blood. | to evaluate the performance of bact/alert fa (fa) medium, a new aerobic bact/alert fan (fan) medium (organon teknika corporation, durham, n.c.) that does not require the added cost and inconvenience of a venting unit, we inoculated blood specimens from adult patients with suspected sepsis into an original fan aerobic culture bottle and an fa bottle. of 7,745 blood culture sets containing both bottles, 5,256 (68%) met the criteria for adequacy of filling. a total of 466 isolates judged to represe ... | 2001 | 11376041 |
| treatment of propionibacterium acnes endophthalmitis. | propionibacterium acnes is a well-known cause of delayed endophthalmitis following cataract surgery. a white intracapsular plaque, keratic precipitates, and hypopyon may be present. although there is no consensus on the treatment approach, recent studies have reviewed the outcomes of relatively large numbers of patients. reasonable treatment options include pars plana vitrectomy and intra-ocular antibiotics with either partial or total capsulectomy/lens exchange. a good visual outcome is possibl ... | 2001 | 11389352 |
| equipotent generation of protective antitumor immunity by various methods of dendritic cell loading with whole cell tumor antigens. | multiple clinically applicable methods have been used to induce dendritic cells (dcs) to express whole cell tumor antigens, including pulsing dcs with tumor lysate, and mixing dcs with apoptotic or live tumor cells. herein we demonstrate, using two different tumor systems, that these methods are equipotent inducers of systemic antitumor immunity. furthermore, tumor lysate pulsed dc vaccines generate more potent antitumor immunity than immunization with irradiated tumor cells plus the classic adj ... | 2001 | 11394500 |
| chronic or saccular endophthalmitis: diagnosis and management. | 2001 | 11405202 | |
| lumbar spondylodiscitis after epidural anaesthesia at a distant site. | 2001 | 11412196 | |
| acne scarring: a classification system and review of treatment options. | acne is a common condition experienced by up to 80% of people between 11 and 30 years of age and by up to 5% of older adults. in some patients, the severe inflammatory response to propionibacterium acnes results in permanent, disfiguring scars. over the past several decades, numerous descriptive terms and surgical techniques have been used to diagnose the types, and improve the appearance, of scarring in those persons with acne. we propose a descriptive, simple, universally applicable acne scar ... | 2001 | 11423843 |
| association between sciatica and propionibacterium acnes. | 2001 | 11438138 | |
| [effects of macrolide therapy on patients with acne vulgaris]. | 2001 | 11439886 | |
| propionibacterium acnes endocarditis in a native valve complicated by intraventricular abscess: a case report and review. | propionibacterium acnes is a constituent of the normal skin flora. it has been described as causing infection on prosthetic valves but very rarely on native valves. we describe a case of aggressive p. acnes endocarditis in a healthy 36-y-old man which infected a native aortic valve and was complicated by an aortic root abscess and review the literature. | 2001 | 11440225 |
| acute bilateral postoperative endophthalmitis in a hla-dq5-positive patient: possible susceptibility to infections. | an unusual case of bilateral acute endophthalmitis in association with the hla-dq5 histocompatibility antigen is reported. a 35-year-old woman with high myopia and cataracts in both eyes underwent phacoemulsification procedures performed in separate sessions using different viscoelastic substances and following the same strict prophylactic measures. after each surgical procedure, she developed s. epidermidis acute endophthalmitis in the right eye and propionibacterium acnes acute endophthalmitis ... | 2001 | 11475399 |
| postoperative proprionibacterium acnes endophthalmitis. | 2001 | 11475531 | |
| optic disk edema as a presentation of propionibacterium acnes endophthalmitis. | to report a patient with an initial presentation of optic disk edema secondary to propionibacterium acnes endophthalmitis. | 2001 | 11476692 |