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aging enhances the insulin resistance in obesity through both receptor and postreceptor alterations.the association between aging and insulin resistance is well recognized. to clarify possible mechanisms, both the binding and the action of insulin were studied in abdominal sc fat cells from two groups of obese nondiabetic women matched for relative weight and fasting insulin levels. the age ranges of the two groups were 16-37 (mean, 28) and 47-77 (mean, 61) yr, respectively. insulin binding was significantly decreased in the elderly (approximately 40%; p less than 0.05), which scatchard analys ...20143941163
fate of n-(2-hydroxypropyl)methacrylamide copolymers with pendent galactosamine residues after intravenous administration to rats.n-(2-hydroxypropyl)methacrylamide (hpma) copolymers bearing galactosamine residues accumulate in the liver after intravenous administration to rats (duncan, r., kopecek, j., rejmanová, p. and lloyd, j.b. (1983) biochim. biophys. acta 755, 518-521). in this study hpma copolymers bearing pendent galactosamine residues (1.0-11.6 mol%) were injected intravenously into rats and their rates of blood clearance and liver accumulation were measured. a level of substitution of 4 mol% was found to be suffi ...19863942780
consecutive lymphoma with monoclonal gammopathy in a married couple.mixed cellularity hodgkin's disease and diffuse non-hodgkin's lymphoma, mixed cell type, occurred consecutively in a husband and wife. both patients demonstrated monoclonal igm gammopathies. the unusual nature and possible significance of these findings are discussed.20133942960
distribution of gamma-carboxyglutamic acid residues in partially carboxylated human prothrombins.the role of gamma-carboxyglutamic acid in prothrombin has been examined using partially carboxylated variant prothrombins isolated from a person with a hereditary defect in vitamin k-dependent carboxylation. these species differ in gamma-carboxyglutamic acid content, distribution, and function, as monitored by metal binding properties, conformational transitions, phospholipid binding, and calcium-dependent coagulant activity (borowski, m., furie, b. c., goldsmith, g. h., and furie, b. (1985) j. ...19863944102
distribution of gamma-carboxyglutamic acid residues in partially carboxylated human prothrombins.the role of gamma-carboxyglutamic acid in prothrombin has been examined using partially carboxylated variant prothrombins isolated from a person with a hereditary defect in vitamin k-dependent carboxylation. these species differ in gamma-carboxyglutamic acid content, distribution, and function, as monitored by metal binding properties, conformational transitions, phospholipid binding, and calcium-dependent coagulant activity (borowski, m., furie, b. c., goldsmith, g. h., and furie, b. (1985) j. ...19863944102
nih consensus conference: osteoporosis. factors contributing to osteoporosis. 20133944667
nih consensus conference: osteoporosis. factors contributing to osteoporosis. 20133944667
[effect of clomiphene therapy and wedge-shaped resection on lh plasma levels in stein-leventhal syndrome]. 20143945492
open window thoracostomy and plastic surgery with muscle flaps in the treatment of chronic empyema.open window thoracostomy (owt) and plastic surgery using myocutaneous flaps of extrathoracic muscles, was done in nine patients with chronic empyema, after conventional therapy had failed. in all these patients, the pleural cavity and bronchopleural fistulas, when present, closed within eight to 61 days (mean 30), after the second stage of surgery comprising the myoplasty; this in turn was performed between three to seven (mean 3.0) months after the owt. all patients were considered cured with a ...20133948551
open window thoracostomy and plastic surgery with muscle flaps in the treatment of chronic empyema.open window thoracostomy (owt) and plastic surgery using myocutaneous flaps of extrathoracic muscles, was done in nine patients with chronic empyema, after conventional therapy had failed. in all these patients, the pleural cavity and bronchopleural fistulas, when present, closed within eight to 61 days (mean 30), after the second stage of surgery comprising the myoplasty; this in turn was performed between three to seven (mean 3.0) months after the owt. all patients were considered cured with a ...20133948551
levels and patterns of intellectual functioning among ld college students: clinical and educational implications. 20143950517
competencies for mainstreaming secondary level learning disabled students. 20143950520
[rabies in greenland]. 20143952837
[intracranial hypertension in the acute stage of a stroke (spinal fluid dynamic and computer-tomographic studies)].the given study aimed to answer the question about the realization in clinical practice of the possibility of the timely identification of the degree of intracranial hypertension in patients with cerebral stroke under continuous monitoring of the intracranial volume/pressure ratios by means of examination of csf changes and ct of the head. on the basis of an analysis of the interrelationship between the severity of neurologic deficit, findings of ct of the head and the results of examination of ...20143953189
iron losses in sweat.the losses of iron in whole body cell-free sweat were determined in eleven healthy men. a new experimental design was used with a very careful cleaning procedure of the skin and repeated consecutive sampling periods of sweat in a sauna. the purpose was to achieve a steady state of sweat iron losses with minimal influence from iron originating from desquamated cells and iron contaminating the skin. a steady state was reached in the third sauna period (second sweat sampling period). iron loss was ...20143953482
hypomagnesemia in digitalized patients. 20103954538
aids encephalitis mimicking alcohol dementia and depression.the authors report a case of encephalitis occurring in a setting consistent with acquired immune deficiency syndrome (aids). they point out that aids and its complications can mimic psychiatric syndromes, including depression and dementia, or delirium related to illnesses such as alcoholism. acting out behavior, seen in the present case, may also be mistaken as a symptom of sociopathy.20133955114
[determination of anionic surface-active substances in the blood serum by a colorimetric method]. 20143957060
purification and partial characterization of a non-o1 vibrio cholerae hemolysin that cross-reacts with thermostable direct hemolysin of vibrio parahaemolyticus.a newly identified hemolysin (nag-rtdh), which is related to the thermostable direct hemolysin (vp-tdh) of vibrio parahaemolyticus produced by non-o1 vibrio cholerae, was studied. nag-rtdh was purified by successive column chromatographies on deae-cellulose and an immunoaffinity column coupled with anti-vp-tdh immunoglobulin. the molecular weight of nag-rtdh was estimated as 18,500, similar to that of vp-tdh, as judged by sodium dodecyl sulfate slab gel electrophoresis, but its charge or molecul ...19863957429
routine admission chest x-ray in the management of hospitalized patients. 20143957607
lice & scabies control. 20143957613
fractured odontoid with fractured superior articular process of the axis. report of three cases.we report three patients in whom a fractured odontoid process was associated with a fracture of the superior articular process of the second cervical vertebra. although there were no signs of neurological disorder, damage to the c1-c2 joint in all three patients made fusion necessary. forced lateral flexion is suggested as the possible mechanism of injury.20143957998
interaction of histidine-rich glycoprotein with fibrinogen and fibrin.histidine-rich glycoprotein (hrgp) is a human plasma and platelet protein of apparently diverse biological functions. in this study a new interaction for hrgp is described. hrgp specifically interacts with fibrinogen as demonstrated by two independent systems. using an enzyme-linked immunosorbent assay it was demonstrated that hrgp bound to adsorbed fibrinogen in a concentration-dependent and saturable manner, with an apparent dissociation constant (kd) of 6.7 nm. the binding was specific, rever ...19863958188
results of semen cryopreservation in young men with testicular carcinoma and lymphoma.sixty-two young men with testicular carcinoma (31 patients) or lymphoma (31 patients) were referred for semen analysis and possible cryopreservation before systemic therapy. seventy-seven percent of the patients, 24 patients with testicular carcinoma and 24 patients with lymphoma, had semen with a decreased chance for fertility (ie, sperm density less than 20 x 10(6)/ml and/or less than 40% motile sperm and/or decreased sperm motility). a decreased number of motile sperm as well as a poor grade ...20143958766
[clinico-roentgenologic evaluation of the efficacy of extra-intracranial microvascular anastomoses in patients with stenoses in the internal carotid artery system].the authors analyse the results of clinical and x-ray examination of 20 patients with stenosing lesions in the system of the internal carotid artery after operations for establishing extra-intracranial microvascular anastomoses (eicma). marked stable neurological symptomatology was encountered before the operation in arterial stenosis of a high degree (more than 50%) and the presence of brain infarctions. in functioning eicma, evolution of stenoses in the system of the internal carotid arteries ...20133962547
endoscopic anatomy of choledochoduodenostomy in relation to clinical observations.thirty patients having undergone choledochoduodenostomy for benign biliary diseases were studied by means of endoscopy. the endoscopic anatomy of the anastomosis was classified into two types. inflammatory changes of the choledochal mucosa adjacent to the stoma were found in nine cases. endoscopy of the proximal and distal (blind) segment of the common bile duct was accomplished in 19 and nine patients, respectively. it is very probable that these inflammatory mucosal changes could lead to compl ...20103962952
influence of isoflurane on hypoxic pulmonary vasoconstriction in dogs.the authors studied the influence of locally administered isoflurane anesthesia on the pulmonary vascular response to regional alveolar hypoxia (hypoxic pulmonary vasoconstriction [hpv]) over a range of cardiac outputs (cos) in seven mechanically ventilated, closed-chest dogs. the right lung was ventilated with 100% o2 throughout the study. the left lung was ventilated with either 100% o2 (normoxia) or an hypoxic gas mixture (hypoxia). different alveolar concentrations of isoflurane (0, 1, and 2 ...19863963450
decontamination of cell lines by selective elimination of mycoplasmas. 19863964004
decontamination of cell lines by selective elimination of mycoplasmas. 19863964004
congenital lower nasolacrimal duct anomaly: a case report.a congenital anomaly of the nasolacrimal system not previously described is reported. the apposition of the distal end of the nasolacrimal duct was not with the nasal cavity as normally occurs prior to birth but to the external skin. as a result the child presented with difficulty with tear drainage and consequent infection--"neonatal conjunctivitis" followed by a facial abscess at the left lower border of the nose. recent embryological studies suggest that this anomaly is due to failure of comp ...20133964482
serum carotene levels in female long-distance runners.hypercarotenemia has been associated with anorexia nervosa and hypothalamic amenorrhea. with the emergence of a spectrum of menstrual dysfunction, including anovulation in women runners, the hypothesis of hypothalamic amenorrhea in these patients has been formulated. other authors have proposed exercise-associated amenorrhea to be distinct from hypothalamic amenorrhea based on endocrine profiles. using carotene as an index test of hypothalamic amenorrhea, we have studied female long-distance run ...20133965316
torsade de pointes: a maximal vulnerability arrhythmia. 20143966319
mitral valve prolapse and ruptured chordae tendineae.to determine the causes of ruptured chordae tendineae and a suspected etiologic role for mitral valve prolapse (mvp), the mitral valve in 25 consecutive and surgically proved cases of chordal rupture were examined. the diagnosis of mvp was made on the basis of redundancy and marked hooding of the mitral leaflets and on histologic changes. mvp was the underlying morphologic abnormality in 23 patients, only 1 of whom had infective endocarditis that was responsible for the rupture. thus mvp was the ...20143966373
diastolic time during recovery from upright exercise in persons without heart disease.to assess the relation between heart rate and diastolic time (cardiac cycle minus electromechanical systole) during the recovery period from upright exercise, 12 normal volunteers were studied immediately after and 2 and 5 minutes after exercise in the upright position. although heart rate was significantly lower at 5 minutes compared with 2 minutes after exercise (106 vs 116 beats/min), there was significant shortening of diastolic time (from 251 to 230 ms) and total diastole per minute (from 2 ...20143966377
renal masses. 20143968744
management of chronic pain.pain is an unpleasant, subjective experience which escapes objective measurements. it is the normal response to the disruption of healthy tissues, but its persistence beyond the period of healing should alert the practitioner to other unrecognized causes. on the other hand, learned pain is a condition resulting mainly from socio-emotional factors in the absence of progressive, invasive and, most of the time, demonstrable pathology. the key to success in the management of a painful condition is a ...20143969229
a one-year survey of campylobacter enteritis and other forms of bacterial diarrhoea in hong kong.the following enteropathogens were isolated from the faeces of 769 (10.2%) of 7,545 patients of whom 5,704 had diarrhoea or abdominal pain, attending a teaching hospital in hong kong during one year: salmonellae 458 (6.1%); vibrio parahaemolyticus 125 (1.7%); campylobacters 108 (1.4%); shigellae 83 (1.1%); others 19 (0.3%). further identification of the campylobacter isolates showed that 63 (58%) were campylobacter jejuni biotype 1, 44 (41%) were c. coli and only one was c. jejuni biotype 2. sev ...19853973381
blood transfusion and athletics. games people play. 20143974666
seasonal distribution of vibrio parahaemolyticus in freshwater environs and in association with freshwater fishes in calcutta.the seasonal distribution of vibrio parahaemolyticus in freshwater environs and in association with freshwater fishes was studied in 1982 and 1983. the occurrence of this organism in water and sediments at the three sites studied was very infrequent and was restricted to the summer months, although it was not always isolated during these months. the association of v. parahaemolyticus with plankton was chiefly confined to the summer months and progressively declined with the onset of monsoons, re ...19853977307
british medical association attacks cigarette smoking. 20143978493
metastatic nontraumatic clostridium septicum osteomyelitis.nontraumatic clostridial infections are rare, but need to be diagnosed and treated early or high morbidity and mortality rates result. we believe that this is the first reported case of metastatic nontraumatic clostridium septicum osteomyelitis. early treatment with surgical debridement and parenteral antibiotics without hyperbaric oxygen was used. an associated occult rectal malignancy was discovered and treated.19853980945
accession of sweet stimuli to receptors. i. absolute dominance of one molecular species in binary mixtures.intensity/time studies of sweetness response in pure solutions of each of nine different sweet stimuli have been carried out. both variables exhibit simple power functions of the form intensity (s) = kscns and persistence (p) = kpcnp. in binary mixtures of these nine stimuli a depression (or negative synergism) of both sweetness intensity and persistence is observed which is predictable from the low exponents of the power functions. combination of both power functions allows the "effective conce ...20143982052
the matching paradigm: an exact test procedure. 20143983294
gastrointestinal tumors in acromegalic patients.more than 30 years ago the association between growth hormone and certain tumors was established in animal studies. however, the few clinical studies on acromegalic patients usually failed to demonstrate such a link. it was only recently that acromegaly was found to be associated with other endocrine tumors and with a high incidence of colonic polyps. in a retrospective study we looked for gastrointestinal cancer in 48 acromegalic patients. five were identified, two cancers of the stomach, two o ...20143984995
computer characterization of vibrio parahaemolyticus & allied sucrose-negative vibrios isolated from aquatic environs of porto novo. 19853988326
nucleotide sequence of the thermostable direct hemolysin gene of vibrio parahaemolyticus.the gene encoding the thermostable direct hemolysin of vibrio parahaemolyticus was characterized. this gene (designated tdh) was subcloned into pbr322 in escherichia coli, and the functional tdh gene was localized to a 1.3-kilobase hindiii fragment. this fragment was sequenced, and the structural gene was found to encode a mature protein of 165 amino acid residues. the mature protein sequence was preceded by a putative signal peptide sequence of 24 amino acids. a putative tdh promoter, determine ...19853988703
can the rapid semiquantitative estimation of serum c reactive protein be adapted for the management of bacterial infection?serum c reactive protein concentrations measured by a laboratory based assay were compared with the semiquantitative results obtained with a visual agglutination method (well-cotest, crp kit). using this agglutination kit, diluting serum 1/10 and 1/20 gave c reactive protein results which could be of more clinical value than those obtained using the 1/2, 1/4, 1/8, and 1/16 dilutions recommended by the manufacturers. the kit was also used on the ward by junior medical staff, who showed that after ...20143988960
[pruritic urticarial papules and plaques of pregnancy]. 20143992718
[threshold status in adolescence]. 20143993103
higher cardol homologues (5-alkenylresorcinols) from rye affect the red cell membrane-water transport.the influence of 5-heptadecenylresorcinol and total rye 5-alkenylresorcinols isolated from rye grains on the red blood cell water permeability was studied using osmotic shrinkage experiments performed in 300 mm sucrose. the studied compounds induced significant increase of erythrocyte water permeability. the threshold concentration needed for the increase of water permeability was in an order of 10(-6) mol/l. the temperature dependence of the observed process showed the discontinuity which was r ...20143993182
[persistent chlamydia infection in cell culture]. 19853993192
[long-term evaluation of the results in sphincterotomies in spina bifida]. 20143993483
activities of the modified polyene n-d-ornithyl amphotericin methyl ester and the azoles ici 153066, bay n 7133, and bay l 9139 compared with those of amphotericin b and ketoconazole in the therapy of experimental blastomycosis.we studied the efficacy of new experimental antifungal drugs, which represent molecular modifications of present active agents, in a murine model of blastomycosis. ketoconazole, previously the best azole drug studied and which is protective when administered orally, was superior to a new oral imidazole, bay l 9139, and a new oral triazole, bay n 7133. a new oral triazole, ici 153066, was markedly more effective than ketoconazole and is the only oral drug studied which came close to producing com ...20143994350
cadmium chloride susceptibility, a characteristic of campylobacter spp.we report a simple diagnostic characteristic useful in the presumptive identification of campylobacter jejuni and campylobacter coli. filter paper disks impregnated with cadmium chloride were placed on streaked agar medium. zones of growth inhibition for campylobacter spp. occurred at 1.25 micrograms per disk. other enteropathogens (salmonella spp., shigella spp., vibrio cholerae, vibrio parahaemolyticus, escherichia coli, and yersinia enterocolitica) were resistant to at least 40 micrograms per ...19853998099
intracorporeal cavernosa streptokinase as adjuvant therapy in the delayed treatment of idiopathic priapism.late treatment of priapism may be associated with unsuccessful aspiration and irrigation of the corpora cavernosa. in such cases intracorporeal instillation of streptokinase resulted in dramatic improvement in detumescence. a subsequent venous shunt procedure achieved good results.20143999206
leads from the mmwr. update: acquired immunodeficiency syndrome--united states. 20143999320
[surgery of disk hernia of the lumbar vertebral canal].53 foraminal lumbar disc herniations have been operated on with 4 surgical different exposures: the classical interlaminar exposure (3 observations), with partial medial foraminotomy, does not allow a good view. the complete facetectomy (36 observations) exposes the foramen well but has a little risk of destabilisation. the external exposure (5 observations), lateral to the facets, seems to be a better approach. but, the "mixed" exposure (9 observations), by adding to the external exposure the i ...20124000363
[surgery of disk hernia of the lumbar vertebral canal].53 foraminal lumbar disc herniations have been operated on with 4 surgical different exposures: the classical interlaminar exposure (3 observations), with partial medial foraminotomy, does not allow a good view. the complete facetectomy (36 observations) exposes the foramen well but has a little risk of destabilisation. the external exposure (5 observations), lateral to the facets, seems to be a better approach. but, the "mixed" exposure (9 observations), by adding to the external exposure the i ...20124000363
[colonoscopic follow up of rectocolonic cancer surgeries. assessment of 64 examinations].a collation of 64 colonoscopic examinations performed on 41 patients operated on for cancer of the colon or rectum is reported. eleven patients (26.8 percent) had positive follow-up endoscopic findings. in 13 enumerated tumoral proliferations. 8 benign polyps and 5 malignant growths were found, one of the latter on the anastomosis, and the other 4 on the remaining colon. 80 percent of these tumoral growths and all malignant tumors were discovered in the two years following surgery. when colonic ...20144004135
effect of fecal pollution on vibrio parahaemolyticus densities in an estuarine environment.vibrio parahaemolyticus densities in the narragansett bay, r.i., estuary were found to significantly correlate with the level of fecal pollution in the water. results of field investigations showed a definite association between the levels of this organism and those of escherichia coli, clostridium perfringens, and enterococci. densities of v. parahaemolyticus were greatest in the near-surface waters of contaminated areas and decreased sharply with both the distance from the sources of fecal pol ...19854004246
typology of male-to-female transsexualism.this study tested a prediction derived from the hypothesis that asexual and bisexual transsexualism are actually subtypes of heterosexual transsexualism. two questionnaire scales measuring erotic attraction to males and females were administered to 163 male-to-female transsexuals. a cluster analysis of their scores divided the subjects into four groups: heterosexual, homosexual, bisexual, and asexual. fisher exact tests were used to compare the frequency with which subjects in the four clusters ...20144004548
digestive tract cell proliferation and food consumption patterns of ha/icr mice.the relationship between the daily pattern of food consumption and the proliferation rate of the oesophagus, stomach, forestomach, small intestine and colon of ha/icr mice was examined. proliferative activity was determined by [3h]tdr incorporation on a wet weight tissue basis, along with selective counting of labelled nuclei. under conditions of ad libitum feeding with a 12 hr light cycle (lights on at 0600) mice eat most of their food during the dark period. a distinct circadian rhythm was obs ...20144005933
phenytoin clearance by continuous ambulatory peritoneal dialysis.phenytoin clearance by continuous ambulatory peritoneal dialysis (capd) was studied in a three-year, 8-month-old child. this dialysis resulted in a clearance rate less than 1 ml/min. this is different from that reported in the literature for regular peritoneal dialysis for phenytoin overdose. unlike regular peritoneal dialysis, capd may not require phenytoin adjustment.20144006737
safer shunt insertion during carotid endarterectomy.the use of shunts during carotid surgery may decrease the risk of perioperative stroke by allowing continued perfusion during the procedure. however, there are risks inherent with shunt usage that occur mainly during insertion. a brief clinical study illustrates the risk of shunt-induced emboli and a technique is described for safer shunt insertion.20144009845
isolation of a new drug-resistance plasmid from a strain of vibrio parahaemolyticus.a new r plasmid, psa55, with a molecular weight of 112 megadaltons (md), was isolated from a strain of vibrio parahaemolyticus with multiple drug resistance. the psa55 plasmid conferred on its host resistance to chloramphenicol, tetracycline, streptomycin, kanamycin, ampicillin, trimethoprim and 2,4-diamino-6,7-diisopropyl pteridine, and belongs to incompatibility group c. the plasmid was transferable to escherichia coli, v. parahaemolyticus, v. alginolyticus and nag bivrio at a frequency of 10( ...19854010538
[epidemiology and early diagnosis of thyroid cancer (based on data from the oncology dispensary of the city of stara zagora, the people's republic of bulgaria)].an epidemiologic study on thyroid gland cancer in the catchment area of stara zagora district oncological dispensary with a population of 645,000 was conducted in 1964-1983. the morbidity rate was 1.62/100,000 population, thyroid cancer amounting to 0.83% of all malignancies. female morbidity was 2.7 times that of males. the highest level of morbidity for both sexes was in the age interval of 31-50 years. morbidity in urban and rural areas was on the ratio of 1.5:1.20144013131
clinicopathological correlation of iga nephropathy in children.22 patients with iga nephropathy aged 7-16 years, 15 of whom were found by mass urine screening of school children, were divided into three groups based on the degree of their proteinuria at admission: group a (n = 6) below 0.5 g/day of urine protein, group b (n = 7) between 0.6 and 3.0, and group c (n = 9) above 3.0 g/day of urine protein. the degree of proteinuria seemed to be related to the severity of pathological changes of the glomerular basement membrane; most severe in group c, moderate ...20144014324
[criteria for the use of chloramphenicol in breeding farms in italy]. 20144015000
[prognosis of myocardial infarction. introduction]. 20144015010
variation of estrogen and progesterone receptor status in breast cancer.in a series of fifty breast cancer patients two estrogen and progesterone receptor assays were performed. in two simultaneous assays (tissue samples taken at the same time) disordant results in estrogen receptor, progesterone receptor and double receptor status were detected in 12%, 12% and 21% of cases respectively. in sequential assays (tissue samples taken with an interval between the samples) this variation was more pronounced, 24%, 36% and 36% respectively. the variation in simultaneous ass ...20144015025
biliary excretion and enterohepatic circulation of 1-nitropyrene metabolites in fischer-344 rats.1-nitropyrene (1-np), present in diesel engine emissions, is a potent mutagen to bacteria, such as those found in mammalian intestinal tract, which contain nitroreductase enzymes. the purposes of this study were to determine the importance of bile as a route of excretion of 1-np metabolites and to determine if reabsorption of biliary metabolites required the presence of intestinal bacteria. the bile ducts of male fischer-344 rats were cannulated, 0.3 or 1.2 mumoles [3h]1-np was given i.v., and b ...19854015679
altered membrane association of glycogen phosphorylase in the dystrophic chicken.the subcellular distribution of glycogen phosphorylase in pectoralis muscle from normal and dystrophic chickens was determined as a function of age. a substantially larger proportion of the total activity was associated with membranous cellular organelles, both mitochondria and sarcoplasmic reticulum, in preparations from dystrophic birds. the difference could be detected as early as 2 weeks ex ovo. interaction of phosphorylase with cellular membranes may provide a probe for the underlying membr ...19854016151
effect of long-term administration of digoxin on exercise performance in chronic airflow obstruction.we have studied the effect of long-term digoxin on exercise performance in 15 patients with pulmonary heart disease due to severe chronic airflow obstruction (fev1/vc ratio 29 +/- 6%: mean +/- sd). digoxin (0.25 mg/day) was given for 8 weeks in a randomized, double-blind crossover, placebo-controlled trial. all patients were ambulatory and had clinical features of right ventricular dysfunction but no clinical evidence of left ventricular dysfunction. assessments included progressive and steady-s ...20144018179
[the so-called nasal glioma].a case of nasal "glioma" is presented. this tumor consists of congenital heterotopic glial tissue and represents an abnormal protrusion of brain substance (exencephalia).20144019191
malignant epidermal tumours. 20144019861
the instability of intestinal clostridial colonisation in living beings. 19854022979
reentrant ventricular arrhythmias in the late myocardial infarction period in the dog. 13. correlation of activation and refractory maps.isochronal maps of ventricular activation were analyzed in dogs 3-5 days after ligation of the left anterior descending coronary artery utilizing a 64-channel multiplexer. isochronal maps of the effective refractory period were determined from 62 epicardial sites and correlated with the activation maps. the ischemia occurring in the surviving epicardial layer prolonged refractoriness in a spatially nonuniform manner. the resulting pattern of refractoriness on the epicardial surface resembled con ...19854028346
noninvasively diagnosed peripheral arterial disease as a predictor of mortality: results from a prospective study.intermittent claudication has been reported in previous studies to approximately double the risk of subsequent mortality. however, a history of claudication is often present in the absence of significant peripheral arterial disease (pad) and absent in the presence of pad. for this reason we evaluated the association between large-vessel and small-vessel pad, measured by highly reliable and valid noninvasive tests, and mortality in 567 older subjects from a defined population followed-up for an a ...20144028377
[in vitro fertilization in reduced male fertility]. 20134029742
detection of the thermostable direct hemolysin gene and related dna sequences in vibrio parahaemolyticus and other vibrio species by the dna colony hybridization test.a specific gene probe for the vibrio parahaemolyticus thermostable direct hemolysin gene was constructed and used to examine the presence or absence of the thermostable direct hemolysin gene or related dna sequences in v. parahaemolyticus and other vibrios by the dna colony hybridization method. the gene probe consisted of a 406-base-pair, completely internal fragment covering 71% of the structural gene with psti linkers added to the ends. six copies of this 415-base-pair psti fragment were clon ...19854030087
arsenic toxicosis and suspected chromium toxicosis in a herd of cattle.arsenic toxicosis and suspected chromium toxicosis were diagnosed in a herd of cattle that ingested ashes from lumber treated with copper, chromium, and arsenic. findings included peracute death, depression, ataxia, weakness, recumbency, and watery diarrhea. chemical analyses of liver, kidney, abomasal contents, rumen contents, and ashes revealed high concentrations of arsenic and chromium. histologically, specimens of abomasum and duodenum had diffuse mucosal degeneration and engorged capillari ...19854030455
the incidence of rhodococcus (corynebacterium) equi in domestic animals and soil. 19854032938
the role of adenosine in the regulation of coronary blood flow in newborn lambs.adenosine is a metabolic vasodilator of the coronary vessels in the adult. whether it plays a similar role in the regulation of coronary blood flow (cbf) in the newborn is not known. we evaluated changes in adenosine release during periods of decreased oxygen supply (hypoxia) and increased oxygen demand (dobutamine infusions). in anesthetized open-chest lambs (age 1 to 8 days), aortic and coronary sinus adenosine concentrations, circumflex cbf, and myocardial oxygen consumption (mvo2) were measu ...19854035574
the heart in hypertension. 20144038422
inhibition of lipases by proteins. a kinetic study with dicaprin monolayers.we report further investigations on protein inhibition of pancreatic and microbial lipases carried out with the monolayer technique. when beta-lactoglobulin a, melittin, serum albumin, myoglobin, and a protein inhibiting lipase from soybean were preincubated with a dicaprin film at a surface pressure of 35 dynes/cm, no activity was detected with horse pancreatic or rhizopus delemar lipases. by contrast, rhizopus arrhizus and geotrichum candidum lipase activities were not impaired under the same ...19854038705
local cerebral glucose utilization in normal female rats: variations during the estrous cycle and comparison with males.the quantitative 2-[14c]deoxyglucose autoradiographic method was used to study the fluctuations of energy metabolism in discrete brain regions of female rats during the estrous cycle. a consistent though statistically nonsignificant cyclic variation in average glucose utilization of the brain as a whole was observed. highest levels of glucose utilization occurred during proestrus and metestrus, whereas lower rates were found during estrus and diestrus. statistically significant fluctuations were ...19854040921
enzyme-linked immunosorbent assays for detection of thermostable direct hemolysin of vibrio parahaemolyticus.several systems for enzyme-linked immunosorbent assay (elisa) of thermostable direct hemolysin (tdh) of vibrio parahaemolyticus were tested, and single-antibody sandwich elisa systems gave satisfactory results. elisa was able to detect as little as several nanograms of purified tdh per milliliter. the method of de jong (j. clin. microbiol. 17:928-930, 1983) and the glutaraldehyde method were successful for preparing conjugates of alkaline phosphatase and anti-tdh antibody. tdh in fluids in intes ...19854044797
aids victims, modern pariahs. 20134048032
postoperative care following internal urethrotomy.a randomized prospective study was set up to assess the role of postoperative catheter drainage and the value of hydraulic self-dilatation of the urethra after internal urethrotomy. sixty-two patients were admitted into the study and followed-up for two years. the results support the use of a no-catheter posturethrotomy management and advocate the encouragement of postoperative hydraulic self-urethral dilatation.20144049610
duodenal perforation associated with tolazoline.a neonate, managed with tolazoline for pulmonary hypertension after repair of a congenital diaphragmatic hernia, developed a duodenal perforation. the role of tolazoline in this condition is discussed, and possible measures to reduce its gastrointestinal side effects are proposed.20144051547
[subtotal thyroid resection in severe, iodine-induced hyperthyroidism].iodine-induced thyrotoxicosis due to iodine application in high amounts in patients with circumscript or disseminated thyroid autonomy, is complicated by a prolonged course, mainly due to a resistance to conservative therapy with thiourea derivates. we therefore decided to perform an early subtotal thyroidectomy in 24 thyrotoxic patients. this measure is in contrast to the common opinion that surgery should only be performed after normalization of thyroid hormones. in all 24 patients with severe ...20144053769
efficacy of trazodone in narcolepsy.a 25-year-old man with narcolepsy and cataplexy experienced partial relief of symptomatology following administration of methylphenidate. moreover, the latter caused extreme agitation and aggression. however, administration of the antidepressant agent trazodone resulted in almost complete alleviation of the narcoleptic and cataplectic attacks within 48 h after initiation of therapy. trazodone, a novel antidepressant agent may be useful in the long-term management of individuals suffering from na ...19854054183
andrew's liver salt as an effervescent in upper gastrointestinal radiography.double-contrast radiography is widely used for examination of the upper gastrointestinal tract. however, it is not practiced routinely in many developing areas, partly because of high cost of the effervescent agents. in a series of 300 upper gastrointestinal tract investigations, andrew's liver salt has proven to be an effective effervescent, releasing adequate gas in more than 80% of the examinations. it disintegrates rapidly with minimal bubble formation and no artifacts. it has high patient a ...20144054498
comparison of api 20e, api rapid e, and api rapid nft for identification of members of the family vibrionaceae.sixty isolates, from nine species of the family vibrionaceae, were tested by the api 20e, api rapid e, and api rapid nft systems. results were compared with those obtained with standard biochemicals. included were 7 aeromonas caviae isolates, 27 aeromonas hydrophilia isolates, 10 aeromonas sobria isolates, 3 plesiomonas shigelloides isolates, 3 vibrio alginolyticus isolates, 3 vibrio cholerae isolates, 1 vibrio fluvialis isolate, 5 vibrio parahaemolyticus isolates, and 1 vibrio vulnificus isolat ...19854056003
luteinized unruptured follicle syndrome in mild endometriosis. assessment with biochemical parameters.failure to extrude an ovum, with subsequent luteinization of the unruptured follicle (luf), has been proposed as a cause of infertility in women with mild endometriosis. to assess the incidence of this process we performed laparoscopies in the early luteal phase on 16 women with mild endometriosis and 8 control subjects. peritoneal fluid was aspirated and a plasma sample obtained concurrently. estradiol (e2) and progesterone (p) concentrations were determined. a review of the literature suggeste ...20144057180
metoclopramide in the diagnosis of pheochromocytoma.cardiovascular and plasma catecholamine responses to metoclopramide (mcp), a dopamine antagonist, were examined in 5 patients with pheochromocytoma, 12 patients with essential hypertension (eht) and 9 normotensive (nt) subjects who displayed symptoms suggestive of pheochromocytoma on a constant daily intake of 100 meq sodium and 80 meq potassium. significant pressor responses to intravenous doses of 5 mg of mcp, which produced no serious pressor episodes and no other undesirable side effects, we ...20144057555
diurnal rhythm of 3-methoxy-4-hydroxyphenylglycol (mhpg): relationship between plasma and urinary levels.plasma and urinary levels of mhpg were determined in six normal volunteers. samples were obtained at 3-hour intervals for plasma and at 12-hour intervals for urine. acrophase, amplitude and period were determined for plasma mhpg levels. a sinusoidal pattern was obtained for diurnal plasma mhpg with a peak at 15:00 hrs. +/- 46 min. urinary mhpg, corrected for creatinine levels, correlated with both 9 am plasma mhpg and with baseline plasma mhpg. furthermore, the relationship between plasma and ur ...20144058250
effect of ocular compression on intraocular pressure.a prospective double-blind controlled study was undertaken to determine the effects of different compression times applied to soften the eye on normal subjects. application of the honan intraocular pressure reducer (hipr) produced a significantly (p less than 0.02) greater decrease in intraocular pressure when applied for 40 minutes (14.3 mmhg sd = 1.7) when compared to a five-minute application (8.8 mmhg sd = 1.7). no untoward effects were noted in these patients. physiologic effects of externa ...20144058845
passive ankle dorsiflexion increases in patients after a regimen of tilt table-wedge board standing. a clinical report.we monitored the result of a tilt table-wedge board routine on the passive ankle dorsiflexion of 20 patients consecutively to determine the effectiveness of the treatment. the calculated frequency of the treatment, which was applied for 30 minutes on each of 5 to 22 treatment days, ranged from 2.3 to 6.4 treatments a week. all patients demonstrated increased passive ankle dorsiflexion. the increases ranged from 3 to 17 degrees and occurred at a calculated rate of 0.11 to 1.0 degrees a day. we be ...20144059330
age-associated alterations in hepatic glutathione-s-transferase activities.age-associated alterations of hepatic cytosolic glutathione-s-transferase (gst) activities towards sulfobromophthalein sodium tetrahydrate (bsp), styrene oxide (stox), trans-4-phenyl-3-butene-2-one (pbo), 1,2-dichloro-4-nitrobenzene (dcnb), and 1-chloro-2,4-dinitrobenzene (cdnb) were investigated in fischer-344 rats of both sexes with ages ranging from 1.5 to 28 months. the gst activities towards pbo and dcnb in male rats increased with age till 6-12 months when maximum values were attained, and ...19854062964
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