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perfusion characteristics of hepatic cavernous hemangioma using intravenous ct angiography (ivcta).thirty-three patients with 35 proven hepatic cavernous hemangiomas (hch) were studied with intravenous ct angiography (ivcta). 15 scans were performed during the first 30 s after bolus (6 ml/s) injection of 50 ml iodinated contrast material. thereafter 2 scans/min were obtained up to 30 min. three criteria were utilized at ivcta to make a specific diagnosis of hch: (1) detection of an intense mural nodular enhancement in the arterial phase. the density in the nodular region(s) should have a dens ...20071855518
trihexyphenidyl enhances physostigmine prophylaxis against soman poisoning in guinea pigs.the protective effects of simultaneous and continuous administration of physostigmine and trihexyphenidyl against soman-induced toxicity were studied in guinea pigs. not only did trihexyphenidyl reduce physostigmine-induced toxicity when it was administered continuously to the animals along with physostigmine, the combination afforded greater protection from soman lethality than did either agent administered alone. the combination pretreatment also gave better protection against soman-induced bo ...19911855620
prospective hospital based study on persistent diarrhoea.a total of 383 children aged less than 5 years suffering from acute watery diarrhoea or dysentery were studied in hospital to determine the rate of persistent diarrhoea. altogether 335 (87.5%) recovered within 13 days. only in 48 (12.5%) did the diarrhoea continue for 14 days or more, and they were considered as having persistent diarrhoea. children aged between 7 and 18 months had a significantly increased incidence of persistent diarrhoea. children suffering from grade ii-iv malnutrition const ...19911855686
[surgical techniques in crohn disease and ulcerative colitis].the usefulness of surgical treatment of inflammatory bowel disease is determined by the results that can be achieved. in crohn's disease, in addition to minimal resections, non-resective procedures such as stricturoplasty, are also available for the treatment of acute and chronic complications. the operative treatment of peri-anal crohn's lesions is determined by the acute or chronic complications that develop. ulcerative colitis can be cured by complete removal of the colorectal mucosa, and mal ...20061855749
[surgical techniques in crohn disease and ulcerative colitis].the usefulness of surgical treatment of inflammatory bowel disease is determined by the results that can be achieved. in crohn's disease, in addition to minimal resections, non-resective procedures such as stricturoplasty, are also available for the treatment of acute and chronic complications. the operative treatment of peri-anal crohn's lesions is determined by the acute or chronic complications that develop. ulcerative colitis can be cured by complete removal of the colorectal mucosa, and mal ...20061855749
objectification of the severity of acute pancreatitis. 20061855764
objectification of the severity of acute pancreatitis. 20061855764
c1r subcomponent polymorphism in japanese: description of a new allele.the polymorphism of c1r was investigated in 570 unrelated japanese individuals using isoelectric focusing and immunoblotting. a total of 11 different c1r phenotypes including a new pattern designated c1r 11-1 were observed. the allele frequencies were c1r*1 = 0.4561, c1r*2 = 0.3377, c1r*5 = 0.1956, c1r*8 = 0.0088 and c1r*r (c1r*9 and c1r*11) = 0.0018. the population data fitted the hardy-weinberg equilibrium. the c1r polymorphism in japanese was shown to be controlled by 3 common alleles, c1r*1, ...20071855783
[infectious endocarditis]. 20071855806
the role of c5 and t-cell receptor vb genes in susceptibility to collagen-induced arthritis.collagen-induced arthritis (cia) is a rodent arthritis model in which immunization with heterologous type ii collagen induces an inflammatory polyarthritis. susceptibility to the disease is mediated by major histocompatibility complex (mhc) genes as well as genes at other loci. previous studies of the swr/j mouse strain, which is resistant to cia despite bearing the susceptible h-2q haplotype, have suggested that this resistance is the result of a deletion of t-cell receptor (tcr) vb gene segmen ...19911855815
isolation of mosquito-pathogenic bacillus sphaericus & b. thuringiensis from the root surface of hydrophytes.attempts were made to isolate b. sphaericus and b. thuringiensis active against mosquito larvae from the root surface of hydrophytes. out of 139 samples processed, 86 b. sphaericus and 23 b. thuringiensis isolates were obtained. sixty two of the b. sphaericus isolates belonged to the serotype h5a5b, 2 to h6 and 22 isolates did not agglutinate with any of the 6 antisera tested. twenty of the b. thuringiensis isolates belonged to the h14 serotype, 1 each to the h10 and h17 serotype(s) and 1 to an ...19911855819
in vitro effect of phyllanthus amarus on hepatitis b virus.to evaluate the effects of p. amarus on hepatitis b virus (hbv) antigens and hbv-dna, initial ethanolic extract and subsequent fractions of the plants were prepared. the whole plant material was dried, powdered and extracted with alcohol and subsequently fractionated in hexane, chloroform, butanol and finally in water. all the material were tested for in vitro effects on hbsag, hbeag and hbv-dna in serum samples positive for hbv antigens followed by the screening of respective antigens by elisa. ...19911855821
subcellular fractions of rat organs contain nitroreductases which reduce n-nitrodimethylamine to n-nitrosodimethylamine.the nasal carcinogen n-nitrodimethylamine was reduced to its n-nitroso analogue n-nitrosodimethylamine in vivo. liver-soluble fraction and brain mitochondria contained enzymes capable of reducing this compound. the activity was only partly inhibited by oxygen; nadph and nadh served as cosubstrates. n-nitromethylamine is also carcinogenic and was reduced by liver cytoplasm to a protein binding species (methyldiazohydroxide?).19911855880
temperature-regulated expression of invasion genes in shigella flexneri is controlled through the transcriptional activation of the virb gene on the large plasmid.the invasion phenotype of shigellae is subject to thermoregulation that is known to be expressed through activation of some invasion (inv) genes such as ipab, ipac, and ipad encoded by the large virulence plasmid of shigella flexneri. the expression of ipa genes is regulated positively by virf through the activation of virb on the plasmid. to identify the mediator for the thermoregulation of the large plasmid, we have studied the effect of temperature on the transcription of virf and virb genes ...19911857209
[hemoptysis disclosing a plasma cell granuloma with intra-bronchial involvement].the authors report a case of a plasma cell granuloma in a young woman of 19 with a past history of congenital rubella, presenting with repeated small haemoptyses related to a pedunculated endo-bronchial tumour. the diagnosis was only made per-operatively, permitting an effective excision.20071857820
acrodysostosis in two generations: an autosomal dominant syndrome.acrodysostosis is a rare syndrome characterized by growth retardation, peripheral dysostosis and mental deficiency. x-rays reveal generalized shortening of metacarpals, metatarsals and phalanges, hyperplasia of the first ray of the feet and premature skeletal maturation. occasionally abnormal interpedicular spinal spaces, increased mandibular angle and hearing loss have been observed. we report a 19-year-old woman and her daughter examined at birth and subsequently at 6 years of age. the clinica ...20061860254
class i and class ii major histocompatibility complex antigens on hepatocytes: importance of the method of detection and expression in histologically normal and diseased livers.methodological differences in major histocompatibility complex (mhc) antigen detection were investigated on isolated, viable hepatocytes and cryostat hepatic sections from 27 children with liver disorders, six of whom had normal histology. class i antigens were constantly found on sections using a three step immunoperoxidase technique after acetone/chloroform fixation, other techniques being less sensitive, or on isolated hepatocytes by indirect immunofluorescence alone. with mechanical isolatio ...20071864983
glucagon-induced changes in plasma thyroid hormone concentrations in healthy dogs resemble "euthyroid sick syndrome".we recently demonstrated that glucagon infusion induced a decline in t3 and a rise in rt3 in anesthetized dogs. these changes in t3 and rt3 may be attributed, at least in part, to anesthesia itself, since general anesthesia is known to cause lowering of t3 and an elevation in rt3 during the perioperative period. therefore, to eliminate the contribution, if any, of anesthesia to these changes in t3 and rt3, we assessed plasma glucose, t3 resin uptake (t3ru), t4, free t4, t3 and rt3 concentrations ...19911865078
bronchial rupture. 20061865682
bronchial rupture. 20061865682
the effects of race on norepinephrine clearance.eighteen normotensive and 19 unmedicated hypertensive black and white male subjects were studied twice, during a 10 meq sodium diet for 5 days and a 200 meq sodium diet for 4 days. the subjects received an infusion of 3h-norepinephrine (3h-ne) during both low and high sodium diets to measure ne clearance. dietary sodium and blood pressure classification had no effect on 3h-ne clearance. infusion of pressor doses of ne also failed to alter 3h-ne clearance. both normotensive and hypertensive black ...20071865747
stress modulates calcium mobilization in immune cells.both acute and chronic restraint stress modulated mitogen-induced increases in cytoplasmic free-calcium concentrations ([ca2+]i) in mouse spleen cells. dual-color analysis of lymphocyte subpopulations demonstrated that acute (2 hour) restraint stress suppressed mitogen-stimulated increases in [ca2+]i in cd4+ t cells, but enhanced [ca2+]i in cd8+ t cells. chronic restraint stress (2 hours daily for up to 21 days) resulted in a significant suppression of mitogen-stimulated increases in [ca2+]i in ...19911865761
replantation in children.the authors have replanted 162 parts in 120 children over the past 15 years. the youngest patient, undergoing successful replantation, was aged 7 months, 3 weeks. unlike an adult, any child suffering a traumatic amputation should be considered for a possible replantation. replantation should consist of minimal bone shortening to preserve epiphyseal plates, with repair of all severed structures. longitudinal k-wires usually provide adequate fixation. our survival rate for complete replantation in ...20071865815
in the aftermath: health care in kuwait city. 20071865865
[contacts between the cells in bacterial colonies].the interaction of cells in microbial colonies has been studied by electron-microscopic techniques. two types of contacts between cells have been found to exist in the colonies of gram-negative bacteria of the genera escherichia, shigella and salmonella: close cell adhesion due to the fusion of cell-wall outer membranes and the formation of intersections consisting of membranous tubules. at the sites of close adhesion the fusion of cytoplasmic and outer membranes have been found to occur in baye ...19911867039
effects of inhaled and oral corticosteroids on bone. 20071867455
heparin-induced thrombocytopenia. 20021867675
effect of prior infection with virulent shigella flexneri 2a on the resistance of monkeys to subsequent infection with shigella sonnei.all virulent shigellae have large plasmids. plasmid-associated genes encode the expression of membrane-associated proteins (map), some of which correlate with the ability to invade susceptible epithelial cells. these map are serologically related in all of the shigella serotypes and evoke an antibody response after infection. to determine whether the map have a significant role in protection, 24 monkeys were infected with virulent shigella flexneri 2a. after recovery, one group (with controls) w ...19911869840
virulence phenotype and genetic characteristics of the t32-istrati shigella flexneri 2a vaccine strain.the t32-istrati strain, which has been used as an oral attenuated shigella flexneri 2a vaccine, has lost the invasive phenotype due to a spontaneous deletion in the shigella virulence plasmid. this deletion has eliminated three plasmid loci (ipabcda, inva and virg) that are necessary for production of a positive sereny test by shigella species. virulence in the sereny test was reconstituted in the t32-istrati strain by the conjugal transfer of an intact 140 m da virulence plasmid from s. flexner ...19911872021
antigen sharing of salmonella typhi non-flagellar proteins with other salmonellae and some shigellae and escherichia coli.cathodal moving protein components were identified in agarose gel electrophoresis of the veronal buffer extract of a non-motile strain of s. typhi (8393, colindale). rabbit antiserum was raised against these cationic proteins; it had both agglutinating and precipitating activity. a total of 80 salmonella strains belonging to serogroups a, b, c1, c2, d, e1 and e2 including 26 s. typhi and 10 s. paratyphi a were tested against this antiserum in a slide agglutination test; all strains were agglutin ...19911874550
distinction of mesothelioma from carcinoma in pleural effusions. an immunocytochemical study on routinely processed cytoblock preparations.the study was designed to find out whether the commercially available antibodies bma 130 c, bma 120, v 9, kl 1, b 72.3 tag, hea 125 and ber-ep 4 would be of help in distinguishing carcinomas from a mesothelial process (mesothelioma/pleuritis) in pleural effusion specimens routinely processed by the cytoblock method. all of the 20 carcinomas included in the study but also 19 of the 20 mesotheliomas expressed cytokeratin (kl 1), whereas vimentin expression was found in 7 of the 20 carcinomas and 1 ...20071876528
different patterns of behavior produced by haloperidol, pentobarbital, and dantrolene in tests of unconditioned locomotion and operant responding.three motor-impairing drugs with different putative mechanisms of action (haloperidol 0.00, 0.075, 0.15, 0.30 mg/kg ip; pentobarbital 0.00, 4.5, 9, 12 mg/kg ip; and dantrolene 0.00, 5, 7.5, 10 mg/kg ip) produced strikingly similar patterns of dose-dependent attenuation in unconditioned locomotor behavior. however, the same drugs and doses produced highly divergent patterns of disruption when tested using different groups of rats in a food-rewarded operant task, which included both response initi ...19911876659
legal case briefs for nurses. or.: did nurse fail to call ambulance?; "hearsay evidence"; ga.: agency seeks injunction vs. former employee: "trade secret". 20071876706
potentials of shigella flexneri y strain tsf21 as a candidate vaccine against shigellosis: safety, immunogenicity and protective efficacy in bonnet monkeys.a thymine-requiring and temperature-sensitive mutant of shigella flexneri y was tested in bonnet monkeys for safety, immunogenicity and protective efficacy. a dose of 10(11) cells when fed orally mimicked natural infection in having invaded epithelial cells, but was otherwise clinically non-reactogenic. animals immunized with two oral doses, each dose consisting of 1 x 10(11) mutant bacteria, were fully protected when challenged, with respect to the lack of any clinical symptoms or detectable hi ...19911878259
a case of shigellosis caused by shigella dysenteriae type 1 and shigella flexneri type 5b.shigella dysenteriae type 1 and shigella flexneri type 5b strains were isolated as causative agents of bacterial dysentery in a patient having visited south-east asia. both strains are a rare finding for bulgaria. s. dysenteriae 1 strains have not been isolated since 1962, and there were only single isolates of s. flexneri 5b. the strains were of the same antibiotic resistance patterns. conjugation experiments showed that resistance is determined by transferrable r-plasmids having identical char ...19911880406
[shigella endotoxin protein--its electrophoretic and serological properties].the electrophoretic analysis of lipid a-associated protein (lap), obtained from s. sonnei, in polyacrylamide gel in the presence of sodium dodecyl sulfate and urea has revealed the heterogeneity of the preparation; it has found to contain three main components with molecular weights of 43, 38 and 18 kd and some minor components with molecular weights of 49, 45 35, 30, 29, 27, 5, 21 and 14 kd. the electrophoretic mobility of the main protein components in the isolated preparation of lap coincides ...19911882599
[the action of ribosomal preparations on nonspecific resistance to bacterial infection and on early tolerance to endotoxic shock].ribosomal preparations from shigella flexneri and shigella sonnei, introduced parenterally into mice, enhance their resistance to infection with the causative agents of typhoid fever and staphylococci. this effect is considerably less pronounced than that produced by the preparation of homologous lipopolysaccharide isolated by boivin's method. after the administration of ribosomes nonspecific resistance to bacterial infective agents lasts for a short time. ribosomal preparations do not enhance t ...19911882607
effects of lactational status on forage intake, digestibility, and particulate passage rate of beef cows supplemented with soybean meal, wheat middlings, and corn and soybean meal.sixteen mature, lactating (453 kg) and 16 nonlactating (487 kg) hereford and angus x hereford cows were used to determine effects of different dietary supplements and lactational status on forage intake, digestibility, and particulate passage rate. supplement treatments and amounts fed (kg/d) were as follows: control, 0; and equal daily amounts of cp from soybean meal (sbm), 1.36; wheat middlings (wm), 3.41; or a blend of corn and soybean meal (corn-sbm; 22% corn and 76% sbm), 3.41. cows were fe ...19911885374
effects of lactational status on forage intake, digestibility, and particulate passage rate of beef cows supplemented with soybean meal, wheat middlings, and corn and soybean meal.sixteen mature, lactating (453 kg) and 16 nonlactating (487 kg) hereford and angus x hereford cows were used to determine effects of different dietary supplements and lactational status on forage intake, digestibility, and particulate passage rate. supplement treatments and amounts fed (kg/d) were as follows: control, 0; and equal daily amounts of cp from soybean meal (sbm), 1.36; wheat middlings (wm), 3.41; or a blend of corn and soybean meal (corn-sbm; 22% corn and 76% sbm), 3.41. cows were fe ...19911885374
respiratory-related recruitment of the masseter: response to hypercapnia and loading.to test the hypothesis that a muscle that closes the jaw, the masseter, can be recruited by ventilatory stimuli, we studied the electromyographic activation of the masseter and genioglossus in seven normal awake males who were exposed in random order to progressive hyperoxic hypercapnia, inspiratory threshold loading (-40 cmh2o), and combined hypercapnia and loading. with hypercapnia, the masseter was generally recruited after the genioglossus had been activated. once recruited, activation of bo ...20071885444
[use of immunofluorescence method in the diagnosis and study of pathogenesis of acute dysentery]. 19911887317
[pathology of the gastrointestinal tract in patients with reactive arthritis and its possible role in the pathogenesis of the disease]. 19911887410
ompb (osmo-regulation) and icsa (cell-to-cell spread) mutants of shigella flexneri: vaccine candidates and probes to study the pathogenesis of shigellosis.genetic and molecular data now available on the pathogenic properties of shigella flexneri allow rational design of live attenuated vaccine strains. the genes required at given steps of the infection process can be selectively mutated to impair the bacterium's capacity to interact with intestinal epithelial cells and/or survive within intestinal tissues in general. we have tested two mutations in s. flexneri serotype 5a (m90t) which, alone or in combination, have yielded promising results when e ...19911887672
[the determination in saliva of iga antibodies to shigella ribosomes for the diagnosis of dysentery].the levels of antiribosomal antibodies to shigella ribosomes in serum and saliva samples from 38 dysentery patients (15 s. sonnei cases and 23 s. flexneri cases), 14 patients with salmonellosis and 136 healthy adults were determined in elisa with ribosomes from s. sonnei r-mutant used as solid-phase antigen. high levels of "normal" antiribosomal iga, igg and igm antibodies were revealed in the sera of healthy persons while the level of salivary iga antibodies was very low. in dysentery infection ...19911887713
[an immunomorphological study of the lymphoid organs in the experimental administration of virulent and avirulent shigella flexneri 2a strains]. 19911887717
simultaneous infection with multiple serotypes of shigellae in a patient.we isolated three different serotypes of shigella on admission from a patient with dysentery as well as a shigella-like organism and campylobacter jejuni upon follow-up. the patient produced serum antibodies to all three serotypes of shigellae.19911889185
if reliance on epidemiology were to become epidemic, we would need to assess its social validity. 20061890043
if reliance on epidemiology were to become epidemic, we would need to assess its social validity. 20061890043
effectiveness of fortnightly tooth brushing with amine fluorides in caries-prone subjects.the aim of this study was to assess the caries incidence and plaque accumulation in schoolchildren at caries risk, after brushing the teeth fortnightly with gels containing 0, 0.4% f, 1.25% f as amine fluoride (amf) or the common amine fluoride toothpaste containing 0.125% f. the study was conducted double blind over an 18-month period, and after 6 months discontinuation of brushing. only the group that brushed with the 1.25% amf gel showed a significant decrease in caries development compared t ...20071890532
relation between airway responsiveness and serum ige in children with asthma and in apparently normal children.although asthma diagnosed by a physician is known to be related to serum ige levels, it is not known whether there is a relation between the level of ige and airway hyperresponsiveness to a methacholine challenge. the characteristics of asymptomatic persons that predispose them to airway hyperresponsiveness are also unknown.20071891008
intravenous immunoglobulin and pyridoxine-dependent seizures. 20071891109
depression in the elderly. characteristics and clinical management.major depression and clinically significant depressive symptoms occur commonly in the community-dwelling, medically ill, and institutionalized elderly. both major depression and depressive symptoms need thorough evaluation and treatment because of the significant morbidity and mortality associated with these syndromes. depression may be difficult to diagnose, especially in the medically ill elderly, because of the masking of depressive symptoms by somatic complaints or the presumption that sympt ...20071891394
echocardiographic determination of aortic and pulmonary valve areas in subjects with normal hearts.two-dimensional and doppler echocardiography were performed in 70 subjects (aged 1 day to 16 years, body surface area from 0.08 to 2.1 m2) to determine aortic and pulmonary valve areas in normal children and adolescents. valve areas were determined by the continuity equation using echo-determined ventricular outflow tract diameters and doppler-determined flow velocities from the outflow tracts and corresponding great arteries. left ventricular outflow tract diameter ranged from 0.3 to 2.2 cm and ...20071892085
[changes in virulence of enterobacteriaceae in the presence of sub-inhibitory levels of antibiotics].the effect of subinhibitory concentrations of antimicrobial agents such as chloramphenicol, tetracycline, rifampicin and nalidixic acid on various factors of virulence in shigella spp. and enteroinvasive colon bacilli was studied. it was shown that under such conditions changes took place in various events of the interaction with the epithelial cells, i.e. in adhesion, penetration, intracellular multiplication and transfers between contacting cells. the total effect of chloramphenicol resulted i ...19911892427
shigella flexneri infection: a histopathologic study of colonic biopsies in monkeys infected with virulent and attenuated bacterial strains.macaca fascicularis monkeys were orally infected with live virulent shigella flexneri wild-type strains of either serotype y (s. flexneri sfl1), 2a (s. flexneri m4243) or 1b (s. flexneri sfl27). clinical signs of shigellosis varied from mild watery diarrhea (sfl1) to dysentery (m4243, sfl27), with a fatal outcome in two monkeys (sfl27). colonoscopy showed slight pathologic changes in monkeys infected with sfl1, and pronounced changes in monkeys infected with sfl27. in colonic biopsies the most s ...19911892634
prostatic cancer: where do we go from here?this paper focuses on advances in prostatic cancer that occurred during the past year. specific areas reviewed here are screening, radical surgery, locoregional disease, the no-therapy option, androgen-ablative therapy, prognostic factors, bone-specific therapy, hormone refractory disease, and prostate cancer biology.20071892925
sharpening of ultrasonic scalers.instruments suitable for removing calculus, plaque and necrotic cementum, which hinder normal periodontal reattachment, are extremely important for successful therapy. the test was carried out in order to see if a standard scaler used for ultrasonic tartar removal maintains its physical features when sharpened. 6 scalers, compatible with piezo-electric generators, were tested and 2 diameters, a and b, weights and resonance frequencies were measured. scalers no. 2, 3, 4, 5, were sharpened and was ...20061894743
cell populations and episodic periodontal attachment loss in humans.the purpose of the present study was to assess possible associations between episodic probing attachment loss and cell populations in the supracrestal connective tissue in humans. 10 systemically healthy adult patients with untreated advanced periodontitis were monitored during a period of 10 months. at baseline and every month thereafter, probing attachment levels were measured at 6 sites of every tooth using an electronic pressure sensitive probe and flexible stents. corresponding contralatera ...20061894744
marking width, calibration from tip and tine diameter of periodontal probes.the present study comprises an investigation of 7 different probe types, representing currently-marketed major designs (who-cpitn, williams, michigan), as well as available calibration systems (engraved, etched and painted markings). width of markings, accuracy of calibration from probe tip, and tine diameter at the tip and at specified points along the tine were assessed, using a stereomicroscope at a magnification of x 40. blind duplicate measurements of these probe tine characteristics were 1 ...20061894745
autotransplantation of third molars as treatment in advanced periodontal disease.the aim of this study was to investigate the prognosis of replacing molars with advanced periodontitis by autotransplanted fully developed third molars. the patient sample consisted of 18 subjects, 24-58 years of age. the patients selected had at least 1 molar with advanced periodontal tissue destruction. after extraction of the diseased molar, autotransplantation of a third molar was immediately performed. after a splinting and healing period of 2-3 weeks, endodontic treatment was carried out. ...20061894746
autotransplantation of third molars as treatment in advanced periodontal disease.the aim of this study was to investigate the prognosis of replacing molars with advanced periodontitis by autotransplanted fully developed third molars. the patient sample consisted of 18 subjects, 24-58 years of age. the patients selected had at least 1 molar with advanced periodontal tissue destruction. after extraction of the diseased molar, autotransplantation of a third molar was immediately performed. after a splinting and healing period of 2-3 weeks, endodontic treatment was carried out. ...20061894746
cytogenesis in the monkey retina.time of cell origin in the retina of the rhesus monkey (macaca mulatta) was studied by plotting the number of heavily radiolabeled nuclei in autoradiograms prepared from 2- to 6-month-old animals, each of which was exposed to a pulse of 3h-thymidine (3h-tdr) on a single embryonic (e) or postnatal (p) day. cell birth in the monkey retina begins just after e27, and approximately 96% of cells are generated by e120. the remaining cells are produced during the last (approximately 45) prenatal days an ...19911894769
quality assessment/assurance activities in u.s. dental schools.quality of health care services has become a major social issue. accordingly, activities directed toward the assessment and assurance of quality are receiving increased attention in dentistry and dental education. the purpose of this study was to determine the status of quality assessment/assurance (qa) programs in u.s. dental schools. responses from 48 u.s. schools identify a range of institutional qa activities currently being conducted in dental education. the evaluation and remedial action e ...20071894825
nifedipine reduces the incidence of myocardial infarction and transient ischemia in patients undergoing coronary bypass grafting.a randomized study was performed on 104 patients undergoing elective coronary artery bypass grafting to examine whether the infusion of nifedipine (n = 53) reduces the incidence of perioperative myocardial ischemia and necrosis in the early postoperative period. continuous hemodynamic and three-channel holter monitoring was performed for 24 hours and serial assessment of serum enzymes and 12-lead electrocardiography were performed for 36 hours postoperatively. nifedipine (minimum dose, 10 microg ...20061899365
nifedipine reduces the incidence of myocardial infarction and transient ischemia in patients undergoing coronary bypass grafting.a randomized study was performed on 104 patients undergoing elective coronary artery bypass grafting to examine whether the infusion of nifedipine (n = 53) reduces the incidence of perioperative myocardial ischemia and necrosis in the early postoperative period. continuous hemodynamic and three-channel holter monitoring was performed for 24 hours and serial assessment of serum enzymes and 12-lead electrocardiography were performed for 36 hours postoperatively. nifedipine (minimum dose, 10 microg ...20061899365
new serologic tests for early detection of coccidioidomycosis.arizona college students suspected of having recently acquired coccidioidomycosis were tested for anticoccidioidal antibodies and circulating fungal antigens using conventional antibody detection methods and new elisa procedures. of 233 patients with compatible symptoms, 26 had anticoccidioidal antibodies detected by conventional tests. elisa detected antibodies in sera from 20 of these patients and also from another 25 patients. patients with antibodies detected by either conventional or elisa ...20071899877
effects of interleukin-6, interleukin-2, and tumor necrosis factor alpha on transferrin release from sertoli cells in culture.recent studies demonstrate that several cytokines are potent modulators of steroid release from the testis. in an attempt to determine whether these agents may influence other types of secreted substances, we used plaque assays to measure the effect of interleukin-6 (il-6), interleukin-2 (il-2), and tumor necrosis factor alpha on transferrin (tf) release from sertoli cells in culture. because sertoli cells from different parts of the tubule respond differently to modulatory factors, we used cult ...19911905226
evidence that inhibin plays a major role in the regulation of follicle-stimulating hormone secretion in the fully adult male rhesus monkey (macaca mulatta).in the juvenile male rhesus monkey in which an adult-like pattern of endocrine activity in the pituitary-testicular axis is imposed by pulsatile stimulation with exogenous gnrh, administration of inhibin antiserum elicits a marked and selective hypersecretion of fsh. this finding suggests that in the monkey, testicular inhibin plays a major role in the postpubertal regulation of this gonadotropin. the purpose of the present study was to confirm this view more directly. to this end, 10 adult male ...19911905228
susceptibility of pseudomonas aeruginosa and escherichia coli biofilms towards ciprofloxacin: effect of specific growth rate.methods of cell culture which enable the control of specific growth rate and expression of iron-regulated membrane proteins within gram-negative biofilms were employed for various clinical isolates of pseudomonas aeruginosa taken from the sputum of cystic fibrosis patients and of a laboratory strain of escherichia coli. susceptibility towards ciprofloxacin was assessed as a function of growth-rate for intact biofilms, cells resuspended from the biofilms and also for newly formed daughter cells s ...19911905285
umbilical cord occlusion stimulates breathing independent of blood gases and ph.the role of umbilical cord occlusion in the initiation of breathing at birth was investigated by use of 16 unanesthetized fetal sheep near full term. artificial ventilation with high-frequency oscillation was used to control fetal arterial blood gas tensions. at baseline, pco2 was maintained at control fetal values and po2 was elevated to between 25 and 50 torr. in the first study on six intact and four vagotomized fetuses, arterial pco2 and po2 were maintained constant during two 30-min periods ...19911905291
measurement of human cerebral monoamine oxidase type b (mao-b) activity with positron emission tomography (pet): a dose ranging study with the reversible inhibitor ro 19-6327.eight normal subjects (3 females and 5 males) were studied using intravenous l-[11c] deprenyl and positron emission tomography. in a single blind study one subject received tracer alone, one subject received an oral pre-dose of 20 mg of l-deprenyl and 6 subjects received oral pre-doses of 10 to 50 mg of a novel reversible mao-b inhibitor (ro 19-6327). dynamic pet scans beginning 12 h after the oral dose were collected over 90 min and arterial blood was continuously sampled. data analysis was mod ...19911906004
capsaicin inhibits airway hyperresponsiveness but not lipoxygenase activity or eosinophilia after repeated aerosolized antigen in guinea pigs.to evaluate the role of tachykinins in airway hyperresponsiveness following repeated aerosolized antigen challenge in guinea pigs, we treated 12 guinea pigs with capsaicin (105.6 mg cumulative dose given subcutaneously over 5 days) after sensitization to ovalbumin (oa) and before three repeated oa aerosol challenges per wk for 4 to 5 wk. ten guinea pigs received identical oa sensitization and challenges without capsaicin treatment, and four of eight nonsensitized controls received capsaicin foll ...19911907116
studies on the pathogenicity of listeria monocytogenes.the characterization of mutants of listeria monocytogenes with reduced virulence properties is described. reduction in the amount of the extracellular protein p60 (encoded by the ipa gene) leads to cell filaments with impaired invasiveness. mutants which cannot synthesize listeriolysin are still invasive but unable to survive within phagocytic cells. one type of listeriolysin-negative mutants is defective in the synthesis of a positive regulatory element prfa which coordinately regulates the lis ...19911908834
intercellular spread of shigella flexneri through a monolayer mediated by membranous protrusions and associated with reorganization of the cytoskeletal protein vinculin.the spread of shigella flexneri in a monolayer of infected henle and hela cells was studied by using immunofluorescence and electron microscopy. infected cells produced numerous bacterium-containing membranous protrusions up to 18 microns in length that penetrated adjacent cells and were subsequently phagocytosed. fluorescence staining of actin and vinculin in infected cells with phalloidin and monoclonal antibody to vinculin, respectively, demonstrated that the protrusions containing the bacter ...19911910001
lymphokines in asthma: are they there and can they be detected? 20071913262
calcium dependence of effects of endothelin on rat mesenteric microvessels.we investigated the calcium dependence of the effects of endothelin (et) on resistance vessels (less than 300 microns lumen diameter) from the mesenteric vascular bed of the rat, mounted on a wire myograph. et-1 induced a potent sustained contraction with an ed50 of 12 nmol/l. the response to et-3 and big et at the maximum concentrations used (100 nmol/l) was less than 40% of that to et-1, with an estimated ed50 of 45 nmol/l. relaxation of the et-1-induced contraction was slow, and resulted in a ...19911913326
biosynthesis of isochorismate in klebsiella pneumoniae: origin of o-2.the shikimate metabolites are key precursors to a large number of natural products, including aromatic amino acids. chorismic acid is an important branch point in the biosynthetic pathway to aromatic amino acids. chorismic acid is also unique among natural products since it is the only compound known to undergo an enzymatic claisen rearrangement. a metabolite of chorismic acid, isochorismic acid, first observed in aerobacter aerogenes differs in its chemical structure by the location of the hydr ...19911913340
gastric volvulus--a late complication of gastrostomy.two cases of gastric volvulus are reviewed. both patients were nonverbal, mentally handicapped children, who were fed through a gastrostomy. they had intermittent intolerance to bolus feeds through the gastrostomy, accompanied by abdominal distension and vomiting of gastric contents. one had a previous partial fundoplication and gastrostomy, and the other had had two pyloroplasties and gastrostomy. the axis of torsion ran from the esophagogastric junction to the gastrostomy site. both children w ...20071913395
the right to remain psychotic. 20071913407
the significance of squamous differentiation in endometrial carcinoma. data from a gynecologic oncology group study.squamous differentiation is identified in about 25% of endometrial adenocarcinomas (ac). its significance has been the subject of debate for decades, and it has been reported that the prognosis of adenoacanthoma (aa) is better than, the same as, and worse than that of ac. part of this confusion has resulted from semantic differences relating to the use of aa and adenosquamous carcinoma (as). to investigate the prognostic importance of squamous differentiation in endometrial carcinomas and compar ...20071913465
relationship of fever magnitude to rate of serious bacterial infections in infants aged 4-8 weeks.we correlated the height of fever with underlying infectious etiology in 683 consecutive febrile infants aged four to eight weeks who received outpatient evaluation for sepsis during a five-year period. the relative number of infants with fever was inversely proportional to fever height, as 51% had a temperature 38.1-38.9 degrees c, 45% had a temperature 39-39.9 degrees c, and 4% had a temperature greater than or equal to 40 degrees c [hyperpyrexia]. there were 34 cases of serious bacterial infe ...19911914347
screening of children for enteric bacterial pathogens in the outborn neonatal ward in lagos, nigeria.babies, on admission into a neonatal ward at the lagos university teaching hospital, had their rectal swab specimens examined bacteriologically and screened for enteric bacterial pathogens over a one-year-period at two-week intervals. it was found that on the average there were 3 (9.68%) enteric bacterial pathogens out of an average of 31 admissions at each screening period. the enteric bacterial pathogens isolated included: non-typhoid salmonellae, which accounted for 55 (80.88%) isolates out o ...19911915794
adenocarcinoma of the ciliary epithelium in a 12-year-old black child.histopathologic examination of a blind eye from a 12-year-old black girl revealed an unsuspected adenocarcinoma of the nonpigmented ciliary epithelium and evidence of previous penetrating trauma. the association between adenocarcinoma of the ciliary epithelium and ocular trauma has been well documented in elderly patients but not in children. the histopathologic distinction between a pleomorphic adenocarcinoma of the ciliary epithelium and a uveal melanoma may be difficult. signs of previous pen ...19671919972
140-mda plasmids of escherichia coli and shigella flexneri 5 do not influence phagocytosis.enteroinvasive escherichia coli (eiec) and shigella flexneri possessing a 140-megadalton (mda) plasmid are capable of invading intestinal epithelial cells and causing dysentery. to determine if this plasmid affected phagocytosis of the organisms by leukocytes, we studied the in vitro phagocytosis of isogenic pairs of eiec and s. flexneri 5 which differed only in the presence or absence of the 140-mda plasmid. in addition five eiec strains containing 140-mda plasmids as well as one non-enteroinva ...19911921856
the effect of caffeine on postprandial blood pressure in the frail elderly.in a double-blind, random-order, cross-over study the effects of placebo and 100 mg of caffeine on postprandial sitting and erect blood pressure and heart rate were studied in 20 frail elderly subjects (mean age 84, range 75-93 years) after a standardized 400 k-calorie glucose drink. maximal postprandial reduction in sitting systolic blood pressure occurred, at 60 minutes post-placebo, of - 11 mmhg (95% confidence interval -5 to -17 mmhg, p less than 0.01), and was attenuated by caffeine (p less ...20071924023
observation and theory in psychoanalysis: the self psychology of heinz kohut.the development of self psychology by heinz kohut illustrates the influence of observational method on theory formation in psychoanalysis. in 1959 kohut began to emphasize empathy and introspection over the traditional combination of free association and evenly suspended attention. this became an important part of a process of revision in psychoanalytic theory which culminated in self psychology. this paper demonstrates how and why that particular change in observational method influenced that p ...20071924603
nucleotide sequence and phylogeny of a chloramphenicol acetyltransferase encoded by the plasmid pscs7 from staphylococcus aureus.the nucleotide sequence of the chloramphenicol acetyltransferase gene (cat) and its regulatory region, encoded by the plasmid pscs7 from staphylococcus aureus, was determined. the structural cat gene encoded a protein of 209 amino acids, which represented one monomer of the enzyme chloramphenicol acetyltransferase (cat). comparisons between the amino acid sequences of the pscs7-encoded cat from s. aureus and the previously sequenced cat variants from s. aureus, staphylococcus intermedius, staphy ...19911929326
aberrant expression of intestinal mucin antigens associated with colorectal carcinoma defined by a panel of monoclonal antibodies.small intestine mucin antigen (sima) is an oncofoetal antigen for the colon and is distinct from the normal large intestinal mucin antigen (lima). in the present study, a panel of anti-sima and anti-lima monoclonal antibodies (mab) was used to charaterise altered mucin expression in colorectal adenocarcinomas, by immunohistochemistry and quantitative immunoassays of tissue extracts. these results are compared with cea expression and correlated with various clinicopathological indices. all mucin ...20071931599
[mr tomography of aneurysmal bone cyst].the preoperative findings of magnetic resonance imaging (mri) in six histology-proven aneurysmal bone cysts (abc) are examined and compared with previous publications concerning mri of abc. the signal intensities differ considerably, and not all of our cases conform with the literature data. they can be summarised in three different subheadings: one form that is very inhomogeneous in t1- and t2-weighting, with fluid-fluid levels in the cystic spaces; one intermediate form without fluid-fluid lev ...20071932722
reactive modifications of the autonomous time structure in the human organism.the spectrum of biological rhythms exhibits characteristic principles of biological time structure which also rule the functional behaviour. with increasing period lengths the rhythms become increasingly complex. in the long-wave section the rhythmic functions find their corresponding cycles in the environment, whereas the shorter waves represent only endogenous autonomous rhythms, which maintain an internal time order by means of frequency- and phase-coordination. under resting conditions and i ...19911932773
an analysis of the acog and aap ethics statements on conflicts in maternal-fetal care. 20071932792
inner city psychiatry. 20071932958
effect of a nonpeptide angiotensin ii receptor antagonist, dup 753, on angiotensin-related water intake in rats.the effect of peripheral administration of the nonpeptide angiotensin ii-1 (aii) receptor blocker, dup 753, on the dipsogenic responses to peripherally administered angiotensins i, ii, and iii was tested. in all cases, dup 753 significantly inhibited the drinking response, whether administered 15 or 45 minutes prior to administration of the dipsogen. these results suggest that the drinking responses to angiotensins i, ii, and iii are mediated by aii-1 receptors. they also suggest that either aii ...19911933441
a new sensitive method for determining endotoxin in whole blood.we developed a microplate method for determining endotoxin in whole blood with endospecy, an endotoxin-specific chromogenic limulus test reagent. the factors in blood that would interfere with the test were successfully removed by exposing samples to 0.66 mol/l hno3 containing 0.25% triton x-100. recoveries of various endotoxins spiked into whole blood of humans and experimental animals were almost complete, and were not enhanced by sample dilution. normal endotoxin concentration in human whole ...19911934509
development of antisera to detect virulent yersinia enterocolitica, shigella and escherichia coli enteroinvasive. 19911935085
molecular epidemiology of plasmid patterns in shigella flexneri types 1-6.a total of 123 drug-resistant and drug-sensitive shigella flexneri types 1-6, and their escherichia coli k12 transconjugants were used for plasmid profile analysis by agarose gel electrophoresis. resistance factors (r-factors) were further characterized by incompatibility testing. the overall distribution of small plasmids in s. flexneri showed that a cryptic plasmid of about 4.6 kb was found in all serotypes, and a plasmid of about 4.2 kb was found in serotypes 1-4. shigella flexneri types 2, 4 ...19911936154
myopic excimer laser keratectomy. a preliminary report. 20071936430
small-animal model to measure efficacy and immunogenicity of shigella vaccine strains.the development of a small-animal model to test the protective efficacy and immunogenicity of a vaccine strain against shigellosis would greatly facilitate the evaluation of potential vaccine candidates. in guinea pigs, the ability of shigellae to invade and multiply within the corneal epithelium, causing keratoconjunctivitis, closely mimics the invasion process in the intestinal epithelium (b. sereny, acta microbiol. acad. sci. hung. 4:367-376, 1957). the serum response of animals recovering fr ...19911937767
inhibition of chemotaxis of neutrophil leukocytes to interleukin-8 by endotoxins of various bacteria.the effects of endotoxins from various bacteria (escherichia coli, klebsiella pneumoniae, vibrio cholerae, shigella flexneri, salmonella typhosa, and pseudomonas aeruginosa) on chemotaxis of neutrophil leukocytes to formyl peptide and interleukin-8 were tested in an improved chemotaxis assay involving a "sparse-pore" polycarbonate (nuclepore) membrane in a boyden-type chamber. the possible chemotactic activity of the endotoxins themselves were tested by the same technique. in addition, the effec ...19911937782
antibody responses in the lungs of mice following oral immunization with salmonella typhimurium aroa and invasive escherichia coli strains expressing the filamentous hemagglutinin of bordetella pertussis.the filamentous hemagglutinin (fha) of bordetella pertussis was expressed in the attenuated aroa mutant of salmonella typhimurium, sl3261, and in a strain of escherichia coli harboring shigella flexneri plasmid pwr110, which encodes bacterial invasiveness for epithelial cells. expression of fha in these strains did not interfere with their ability to invade henle cells. immunoglobulins a and g specific for fha were detected in lung washes of mice following oral immunization with the live recombi ...19911937797
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