Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| nosocomial diskitis due to propionibacterium acnes. | 1998 | 9617690 | |
| contribution of cd14 to endotoxin-induced liver injury may depend on types of macrophage activation in rats. | activated kupffer cells and hepatic macrophages can produce massive liver necrosis through microcirculatory disturbance due to sinusoidal fibrin deposition. this mechanism is involved in the development of liver injury after endotoxin administration in rats pretreated with heat-killed propionibacterium acnes (p.acnes) or undergoing 70% liver resection. the significance of cd14, a receptor for lipopolysaccharide and its binding protein, was evaluated in both models in relation to the activation m ... | 1998 | 9618280 |
| corynebacterium parvum pleurodesis and survival is not significantly influenced by pleural ph and glucose level. | this study was carried out in the pulmonary department of a referral training hospital for thoracic medicine and surgery, with the aim of assessing the effects of ph and glucose level of a pleural effusion (pe) on survival and the response to pleurodesis (pd) with corynebacterium parvum. a prospective study was carried out in 204 patients with recurrent, symptomatic pes (73 benign, 131 malignant). fifty eight per cent of 204 pes had low ph (< 7.20; 7.01 +/- 0.14) nd glucose levels (< 60 mg.dl-1; ... | 1998 | 9632902 |
| aerobic and anaerobic microbiology of chronic venous ulcers. | the role of bacteria in the pathogenesis of chronic venous leg ulcers (cvlu) is unclear. the objective of the study was to establish the aerobic and anaerobic bacteriology of cvlu. | 1998 | 9646126 |
| microbiology of cervical lymphadenitis in adults. | the microbiology of needle aspirates from 40 inflamed cervical lymph glands was studied for aerobic and anaerobic bacteria, fungi and mycobacteria. forty-two bacterial, 11 mycobacterial and six fungal isolates were isolated. aerobic bacteria only were recovered in 11 (27.5%), anaerobes alone in five (12.5%) and mixed aerobic and anaerobic bacteria in seven (17.5%). mycobacterium sp. were recovered in 11 (27.5%) and fungi in six (15%). the recovery of anaerobes was associated with dental infectio ... | 1998 | 9655225 |
| immunologic function in horses after non-specific immunostimulant administration. | inactivated propionibacterium acnes is a biologic response modifier for treatment of non-specific respiratory disease in horses. the objectives of this investigation were to determine alterations in phagocytic activity, phenotypic expression of lymphocyte subpopulations and lymphokine-activated killing cell response in healthy young horses. samples were collected on day 0, 7 and 14 of the investigation. blood samples were obtained via jugular venipuncture and pulmonary leukocytes were recovered ... | 1998 | 9656421 |
| subgingival microflora associated with nifedipine-induced gingival overgrowth. | the purpose of this study was to examine the composition of subgingival plaque of 140 periodontal lesions in 35 patients with cardiovascular disorders who were administered nifedipine and manifested nifedipine-induced gingival overgrowth (go). age was inversely associated with the go. plaque index and bleeding index showed a significant association with go, while nifedipine dosage and duration of nifedipine therapy were not found to be significant predictors of go. the gingival inflammation as e ... | 1998 | 9660335 |
| comparative in vitro activity of bay 12-8039 and five other antimicrobial agents against anaerobic bacteria. | the in vitro activity of bay 12-8039 against 360 anaerobic clinical isolates was determined by the agar dilution method and compared to that of five other antimicrobial agents. bay 12-8039 and imipenem were the most active agents tested. the following mic90 values were determined for bay 12-8039: peptostreptococcus spp. (50 isolates), 1 mg/l; propionibacterium acnes (30 isolates). 0.25 mg/l; clostridium perfringens (30 isolates), 0.5 mg/l; clostridium difficile (50 isolates), 2 mg/l; bacteroides ... | 1998 | 9665302 |
| percutaneous suction aspiration and drainage for pyogenic spondylitis. | retrospective evaluation of results in 23 cases of early-stage pyogenic spondylitis treated with percutaneous suction aspiration and drainage. | 1998 | 9682317 |
| pancreatic fluid collections: diagnostic and therapeutic implications of percutaneous drainage guided by ultrasound. | the aim of the present study is to assess the usefulness of biochemical and bacteriological analysis of the pancreatic fluid obtained at percutaneous drainage of pancreatic pseudocysts and abscesses guided by ultrasound. | 1998 | 9684149 |
| improved detection of infection in hip replacements. a currently underestimated problem. | our aim was to determine if the detection rate of infection of total hip replacements could be improved by examining the removed prostheses. immediate transfer of prostheses to an anaerobic atmosphere, followed by mild ultrasonication to dislodge adherent bacteria, resulted in the culture of quantifiable numbers of bacteria, from 26 of the 120 implants examined. the same bacterial species were cultured by routine microbiological techniques from only five corresponding tissue samples. tissue remo ... | 1998 | 9699813 |
| [bacterial colonization of conjunctiva with propionibacterium acnes before and after polyvidon iodine administration before intraocular interventions]. | propionibacterium acnes has been described as a causative agent of postoperative endophthalmitis. this gram-positive, immotile, non-spore-forming bacterium is highly pleomorphic and grows under conditions of low to no oxygen concentration. it is commonly found on the skin at the openings of sebaceous glands and on hairs. a near-symptomless postoperative endophthalmitis occurs particularly when propionibacteria are enclosed in the capsular bag. we investigated to what extent the number of p. acne ... | 1998 | 9703725 |
| hepatoprotective effect of propagermanium on corynebacterium parvum and lipopolysaccharide-induced liver injury in mice. | propagermanium is an organic germanium compound with immunopotentiating activity. we examined the hepatoprotective effect of propagermanium and its mechanism in an experimental animal model of acute liver injury induced with corynebacterium parvum (c. parvum) and lipopolysaccharide (lps) injection. oral pretreatment with propagermanium decreased alanine aminotransferase (alt) and aspartate aminotransferase (ast) activity in a dose-dependent manner. significant attenuation of alt and ast activity ... | 1998 | 9716110 |
| in vitro activity of hmr 3647 against anaerobic bacteria. | the aim of the present investigation was to determine the in vitro activity of hmr 3647 compared with other antimicrobial agents against anaerobic bacteria. the activity of hmr 3647 was determined against 342 clinical isolates of anaerobic bacteria by the agar dilution method and was compared with azithromycin, clarithromycin, roxithromycin, erythromycin, cefoxitin, imipenem, clindamycin and metronidazole. among the macrolides hmr 3647 and among the beta-lactams imipenem were the most active age ... | 1998 | 9720465 |
| [chronic postoperative endophthalmitis caused by propionibacterium acnes]. | there is a report of three cases of chronic postoperative endophthalmitis following cataract operations. in two patients there was proven propionibacterium acnes. there is presented a technique to obtain specimens for microbiological examination and an overview of clinical experience in treatment of the mentioned less common types of endophthalmitis. early surgical treatment as well as intraocular injection of vancomycin can help to restore a good visual acuity despite of longlasting inflammatio ... | 1998 | 9721491 |
| superficial suppurative thrombophlebitis in children, caused by anaerobic bacteria. | the purpose of this study was to present the microbiology and clinical features of six children with superficial suppurative thrombophlebitis (sst) caused by anaerobic bacteria. | 1998 | 9722004 |
| surface enhanced raman spectroscopic monitor of p. acnes lipid hydrolysis in vitro. | surface enhanced raman spectroscopy (sers) at a silver microelectrode was used to monitor bacterial hydrolysis of triglycerides in lipid mixtures that model sebaceous gland secretions. mixtures of wax esters, squalene, triolein, and triisostearin were used as model skin secretions. the transformation was followed in vitro as changes in the sers caused by hydrolysis of triglyceride to fatty acid. the fatty acid was adsorbed as its carboxylate, which is readily identified by the characteristic ban ... | 1998 | 9741703 |
| propionibacterium [correction of proprionibacterium] acnes infections of cerebrospinal fluid shunts. | ventricular cerebrospinal fluid shunt infections with propionibacterium acnes are generally low-grade, indolent infections. typical presentations include gradual shunt malfunction, nausea, headache, malaise, and infrequently, fever. in all, 489 shunt procedures performed between january 1992 and december 1995, and in 15 of these cases p. acnes was subsequently cultured from reservoir taps or an intraoperative culture which was obtained when the existing shunt components were revised. six of thes ... | 1998 | 9753404 |
| mechanism of suppressed neutrophil mobilization in a mouse model for binge drinking: role of glucocorticoids. | the goals of this study were to determine if suppression of neutrophil accumulation and tnf-alpha production in the peritoneal cavity occurs in mice exposed to a chemical stressor [ethanol (etoh)], to evaluate the role of etoh-induced increases in endogenous glucocorticoids in any such suppression, and to determine if decreased tumor necrosis factor-alpha (tnf-alpha) production is responsible for decreases in neutrophil accumulation in etoh-treated mice. an inflammatory response induced in the p ... | 1998 | 9756533 |
| update on acne. | acne is a common condition seen routinely by both primary care physicians and dermatologists. most patients have no underlying pathology and respond to traditional treatment; others, however, require more individualized evaluation and aggressive therapy. new information regarding the pathogenesis and treatment of acne is now available. this update discusses the proper evaluation of early childhood acne, the emergence of propionibacterium acnes resistance, and the rare but serious side effects oc ... | 1998 | 9757362 |
| systematic review of propionibacterium acnes resistance to systemic antibiotics. | to document changes in the prevalence of resistance of propionibacterium acnes to antibiotics used for treating acne. | 1998 | 9762064 |
| [effect of silymarin on mouse liver damage, production and activity of tumor necrosis factor]. | tumor necrosis factor (tnf) has been well-characterized as a prominent mediator in the development of liver injury. effects of silymarin (sb) on mouse liver damage, tnf production and activity were studied. pretreatment with sb (25-50 mg.kg-1, i.p., bid x 3 d) before the lipopolysaccharides (lps) injection markedly alleviated liver injury and diminished lps-induced tnf production in propionibacterium acnes (pa)-primed mice. sb (12.5-50 micrograms.ml-1) significantly inhibited lps-induced tnf rel ... | 1996 | 9772703 |
| effect of vaccination and the immunomodulators "bacillus of calmette-guérin, avridine and propionibacterium acnes" on rabies in mice. | responses of vaccination and treatment to immunomodulators against rabies in mice were evaluated through macrophage inhibition factor (mif), intra-pad inoculation (ipi) and serum neutralization (sn) tests and by the detection of gamma-interferon (ifn-gamma). onco-bcg, avridine and propionibacterium acnes were administered to groups of mice. higher survival rates were found in animals treated with p. acnes. lower levels of ifn-gamma were observed in the groups of infected and vaccinated mice. the ... | 1998 | 9775360 |
| establishment of the cells useful for murine interleukin-18 bioassay by introducing murine interleukin-18 receptor cdna into human myelomonocytic kg-1 cells. | we genetically engineered human myelomonocytic kg-i cells by introducing cdna of murine interleukin-18 receptor (muil-18r) and established human cells which were capable of responding to muil-18. these cells expressed larger number of muil-18r (> 13,000 sites/cell) than intrinsic human il-18 receptor (huil-18r) (< 2,500 sites/cell). and the cells responded to muil-18 as well as to huil-18 in a dose-dependent manner, and produced large amounts of interferon-gamma (ifn-gamma). we could estimate th ... | 1998 | 9776579 |
| propionibacterium acnes isolated from synovial tissue and fluid in a patient with oligoarthritis associated with acne and pustulosis. | this report describes the case of a patient with a 14-month course of severe oligoarthritis associated with acne. pure cultures of propionibacterium acnes were isolated from synovial tissue and synovial fluid specimens collected from the same joint after a 4-month interval. after 2 months of treatment with roxithromycin 300 mg/day, rifampicin 1,200 mg/day, and a nonsteroidal antiinflammatory drug (nsaid), followed by 4 months of treatment with azithromycin 1 gm/week and an nsaid, the synovitis p ... | 1998 | 9778232 |
| effect of fk506 on the activation state of hepatic macrophages in propionibacterium acnes-treated rats. | activated hepatic macrophages can provoke massive liver necrosis following endotoxin stimulation through microcirculatory disturbances due to sinusoidal fibrin deposition in rats pretreated with heat-killed propionibacterium acnes. in these rats, fk506 (tachlorinus) administered 24 h before and at the time of endotoxin injection, significantly attenuated liver injury compared with the rats given no fk506. the effect of fk506 on hepatic macrophage activation and its action sites were studied in p ... | 1998 | 9792034 |
| suppression of murine endotoxin response by e5531, a novel synthetic lipid a antagonist. | as a consequence of blood-borne bacterial sepsis, endotoxin or lipopolysaccharide (lps) from the cell walls of gram-negative bacteria can trigger an acute inflammatory response, leading to a series of pathological events and often resulting in death. to block this inflammatory response to endotoxin, a novel lipid a analogue, e5531, was designed and synthesized as an lps antagonist, and its biological properties were examined in vitro and in vivo. in murine peritoneal macrophages, e5531 inhibited ... | 1998 | 9797210 |
| [bacteremia in intra-arterial angiography, percutaneous transluminal angioplasty and percutaneous transhepatic cholangio-drainage]. | prospective evaluation of the rate of bacteremia attributed to invasive radiological techniques. | 1998 | 9819654 |
| bacterial eradication from root dentine by ultrasonic irrigation with sodium hypochlorite. | the study aimed to evaluate intracanal irrigation procedures in eradicating bacteria from surface, shallow and deep layers of root dentine using extracted human teeth. artificial bacterial smear layer was successfully produced by rubbing a mixture of dental plaque and artificially decalcified dentine or carious dentine on root canal walls. the reservoir holes were 3.5 mm in depth, 1 mm in diameter prepared 1.5 mm apart and parallel to the root canals on the decrowned planes, in which five separa ... | 1998 | 9823113 |
| propionibacterium acnes sepsis in a previously healthy man. | 1998 | 9827299 | |
| the anti-lipase activity of shiunko on propionibacterium acnes. | 1998 | 9832288 | |
| pivotal role of tarc, a cc chemokine, in bacteria-induced fulminant hepatic failure in mice. | thymus and activation-regulated chemokine (tarc) is a recently identified lymphocyte-directed cc chemokine which specifically chemoattracts t helper type 2 cd4(+) t cells in human. to establish the pathophysiological roles of tarc in vivo, we investigated whether a monoclonal antibody (mab) against tarc could inhibit the induction of hepatic lesions in murine model using propionibacterium acnes and lipopolysaccharide (lps). p. acnes-induced intrahepatic granuloma formation in the priming phase i ... | 1998 | 9835618 |
| [propionibacterium acnes infectious endocarditis]. | propionibacterium acnes, a gram positive microaerophilic bacteria is considered to have a low level of virulence. nevertheless, it can be associated with infective endocarditis. we report 2 cases and a review of the literature. | 1998 | 9856128 |
| [skin reactions to antigens of propionibacterium acnes in patients with acne vulgaris treated with autovaccine]. | one of the most common diseases of the skin is acne. the etiology and pathogenesis of acne, in spite of the advancement of medical knowledge, remain unknown and the effects of treatment unsatisfactory. the mechanism of the beneficial effects of immunotherapy in some cases of acne, including autovaccines prepared from the bacterial strains of the patient, also awaits explanation. the present work was aimed at elucidating the influence of autovaccine on some parameters of specific humoral and cell ... | 1998 | 9857532 |
| [effect of matrine on mouse hepatitis and tumor necrosis factor production induced by propionibacterium acnes/lipopolysaccharides]. | the effect of matrine (mat) on lipopolysaccharides (lps)-induced fatal hepatitis and tumor necrosis factor (tnf) production in propionibacterium acnes (pa)-primed mice were studied. mice were injected i.p. lps (10 micrograms/mouse) 7 d after i.p. pa (0.5 ml/mouse) to induce fatal hepatitis. after i.p. lps, serum tnf activity rose to 1657 +/- 406 ku.l-1 at 1.5 h and alt activity increased up to 1,496 +/- 890 u.l-1 at 5 h. six of 8 mice died within 5 h and the massive hemorrhagic necrosis of the l ... | 1996 | 9863231 |
| pacemaker-induced endocarditis due to propionibacterium acnes. | 1998 | 9868683 | |
| prospective evaluation of external ocular microbial growth and aqueous humor contamination during cataract surgery. | to analyze the route of aqueous humor contamination leading to the development of postoperative endophthalmitis. | 1999 | 9888079 |
| polymerase chain reaction in the diagnosis of bacterial endophthalmitis. | microbiological investigations of vitreous fluid (vf) and aqueous humour (ah) specimens have often failed to detect the infecting agent in infectious endophthalmitis, resulting in a clinical dilemma regarding therapy. in this study, the polymerase chain reaction (pcr) was evaluated in the diagnosis of bacterial and propionibacterium acnes endophthalmitis. | 1998 | 9893601 |
| alleviation of lipopolysaccharide-induced acute liver injury in propionibacterium acnes-primed ifn-gamma-deficient mice by a concomitant reduction of tnf-alpha, il-12, and il-18 production. | the present study was designed to investigate the role of ifn-gamma in lps-induced liver injury following priming with propionibacterium acnes. at 1 week after priming balb/c mice with p. acnes, a large number of macrophages (mphi) and lymphocytes predominantly infiltrated the portal area, resulting in the intrahepatic formation of granulomas consisting of epithelioid and lymphoid cells. in comparison, in ifn-gamma gene-disrupted balb/c mice (ifn-gamma knockout mice), the number of infiltrated m ... | 1999 | 9916732 |
| antimicrobial susceptibility of propionibacterium acnes isolated from acne vulgaris. | systemic and topical antimicrobial treatment for acne vulgaris remains the mainstay method of therapy in japan. strains of propionibacterium acnes (p. acnes) resistant to erythromycin (em), clindamycin (cldm), tetracycline (tc), doxycycline (doxy) and minocycline (mino) have been reported. the aim of the present study was to examine the antimicrobial susceptibility to 10 currently used antimicrobial agents of 50 strains of p. acnes isolated from acne lesions and identified using a rap id ana ii ... | 1999 | 9920982 |
| [in vitro resistance of propionibacterium acnes and staphylococcus epidermidis to antibiotics: should our antibiotic prescription practices for the treatment of acne be changed?]. | 1998 | 9922858 | |
| [the resistance of propionibacterium acnes and staphylococcus epidermidis to cyclines. the research and study group on acne]. | a rising percentage of tetracycline-resistant propionibacterium acnes strains has been reported in the english literature. | 1998 | 9922860 |
| resistance to antibiotics used in dermatological practice. | the increased prevalence of bacterial resistance is one of the major problems of medicine today. antibiotic resistance can be defined as the situation where the minimal inhibitory concentration is greater than the concentration obtainable in vivo. resistance genes are easily transferred among bacteria, especially bacteria on skin and mucous membranes. in dermatological patients the most important resistance problems are found among staphylococci, propionibacterium acnes and, to some extent, stre ... | 1998 | 9990406 |
| role of macrophage scavenger receptors in hepatic granuloma formation in mice. | in mice homozygous for the gene mutation for type i and type ii macrophage scavenger receptors (msr-a), msr-a-/-, the formation of hepatic granulomas caused by a single intravenous injection of heat-killed corynebacterium parvum was delayed significantly for 10 days after injection, compared with granuloma formation in wild-type (msr-a+/+) mice. in the early stage of granuloma formation, numbers of macrophages and their precursor cells were significantly reduced in msr-a-/- mice compared with ms ... | 1999 | 10079248 |
| brain energy stores in c57bl/6 mice after c. parvum injection. | activation of the immune system has been associated with the development of fatigue of unknown cause. we were interested in brain energy stores (e.g., phosphocreatine (pcr) and creatine kinase) after immune activation to investigate whether this system was altered. in this model, fatigue (defined as > 50% reduction in spontaneous running) was induced in c57bl/6 mice after a single injection of corynebacterium parvum antigen. maximal fatigue (about 86% reduction on day 10 post injection) was asso ... | 1999 | 10094158 |
| in vitro activity of 6 antimicrobials against propionibacteria isolates from untreated acne papulopustulosa. | in the present study, mic values of 6 antibiotics were determined for 70 propionibacterium acnes and 13 p.granulosum strains from 71 untreated acne patients using the agar dilution method. the interpretation of in vitro results is difficult because there are only poor data about the concentrations of antibiotics achievable in the sebaceous gland infundibulum. based on breakpoint concentrations according to din 58,944, no resistance was found against chlortetracycline, doxycycline, minocycline, a ... | 1999 | 10096167 |
| endogenous mouse interleukin-10 is up-regulated by exogenously administered recombinant human interleukin-10, but does not contribute to the efficacy of the human protein in mouse models of endotoxemia. | in murine models of experimental endotoxemia, inflammatory cytokines as well as antiinflammatory interleukin-10 (il-10) appear in the circulation after the injection of lipopolysaccharide (lps). there is considerable experimental evidence to suggest that the major function of endogenously produced il-10 is to down-regulate inflammatory cytokine production. indeed, the protective effects of exogenously administered il-10 against murine endotoxin lethality have been shown to correlate with its abi ... | 1999 | 10102793 |
| possible implication of sterile connecting device in contamination of pooled platelet concentrates. | considering the possibility that a pooled random donor platelet concentrate could become contaminated by welding with a sterile connecting device, we undertook a study to determine the influence of pooling on the contamination rate. as a control group, apheresis platelets were examined. bacteriological testing was done with a sensitive co2 detecting culture system, the bact/ alert. out of 1105 pooled platelet concentrates prepared by the buffy coat method, 15 (1.4%) were confirmed as contaminate ... | 1997 | 10175151 |
| defective interleukin (il)-18-mediated natural killer and t helper cell type 1 responses in il-1 receptor-associated kinase (irak)-deficient mice. | interleukin (il)-18 is functionally similar to il-12 in mediating t helper cell type 1 (th1) response and natural killer (nk) cell activity but is related to il-1 in protein structure and signaling, including recruitment of il-1 receptor-associated kinase (irak) to the receptor and activation of c-jun nh2-terminal kinase (jnk) and nuclear factor (nf)-kappab. the role of irak in il-18-induced responses was studied in irak-deficient mice. significant defects in jnk induction and partial impairment ... | 1999 | 10190904 |
| acne neonatorum: a study of 22 cases. | acne is not uncommon in the neonatal period. acne neonatorum is characterized by a mainly facial eruption of inflammatory and noninflammatory lesions. it is most commonly mild and transient. hyperactivity of sebaceous glands, stimulated by neonatal androgens, has been implicated as the underlying pathogenetic mechanism. | 1999 | 10192162 |
| functional roles of mcp-1 in propionibacterium acnes-induced, t cell-mediated pulmonary granulomatosis in rabbits. | the immunological manifestation of granuloma formations in humans largely depends on the delayed-type hypersensitivity response. we investigated the involvement of monocyte chemoattractant protein-1 (mcp-1) in a rabbit model of t cell-mediated pulmonary granulomatosis. intravenous injection of propionibacterium acnes (p. acnes) into sensitized rabbits induced massive and diffuse pulmonary granulomas. levels of mcp-1 in sera and bronchoalveolar lavage fluids (balf) peaked before the granuloma for ... | 1999 | 10204577 |
| propionibacterium acnes: interaction with complement and development of an enzyme-linked immunoassay for the detection of antibody. | to characterize the immune response to propionibacterium acnes in acne patients. | 1999 | 10208616 |
| coagulase-negative staphylococci are the most common bacteria found in cultures from the deep portions of hidradenitis suppurativa lesions, as obtained by carbon dioxide laser surgery. | the significance of bacterial findings in hidradenitis suppurativa (hs) is controversial. interpretation of the results of bacteriological examinations from the surface of hs lesions is obscured by the possible contamination of resident skin bacteria. bacteriological analysis of aspirates from deeper parts of hs is liable to show low sensitivity. we used a carbon dioxide (co2) laser method to evaporate the diseased tissue level by level from the surface downwards, allowing concurrent sampling of ... | 1999 | 10215774 |
| [bacterial resistance during anti-acne antibiotic therapy. how to limit the risk]. | the treatment of moderate to severe acne often relies on antibiotherapy in order to eradicate as much as possible microorganisms such as propionibacterium spp colonizing the sebaceous follicles. in recent years, bacterial resistances against specific antibiotics have emerged. both the antibiotic and its administration modalities must be considered in order to control the risk. with regard to this conundrum, minocycline is a medication of choice among the diverse anti-acneic therapies. | 1999 | 10221062 |
| il-18-deficient mice are resistant to endotoxin-induced liver injury but highly susceptible to endotoxin shock. | il-18 is an il-1-related cytokine which shares biological functions with il-12. these include the activation of nk cells, induction of ifn-gamma production and th1 cell differentiation. in this study we analyzed the effect of il-18 deficiency on lipopolysaccharide (lps)-induced liver injury and endotoxin shock in propionibacterium acnes-primed mice. p. acnes-primed il-18-deficient (il-18ko) mice showed resistance to lps-induced liver injury. unexpectedly, p. acnes-primed il-18ko mice were highly ... | 1999 | 10221659 |
| corynebacterium parvum- and mycobacterium bovis bacillus calmette and guerin-induced granuloma formation in mice lacking cd4 and cd8. | granuloma formation is a t-cell-dependent inflammatory response that is important in the host defense against intracellular bacteria. the role of cd4 and cd8 molecules in the development of corynebacterium parvum- and mycobacterium bovis bacillus calmette and guerin (bcg)-induced granulomas was examined in cd4/cd8 knockout (ko) mice. cd4/cd8 ko mice developed a greater granulomatous response to heat-killed c. parvum and heat-killed bcg than did control mice. thus, granuloma formation is not depe ... | 1999 | 10222057 |
| propionibacterium as a cause of postneurosurgical infection in patients with dural allografts: report of three cases. | although propionibacterium acnes is a common inhabitant of human skin, it is an uncommon pathogen in postoperative infections. we report three cases of postoperative wound infection/osteomyelitis caused by p. acnes. | 1999 | 10232551 |
| in vitro activity of ly 333328 against anaerobic gram-positive bacteria. | ly 333328 is a new semisynthetic glycopeptide with reported activity against aerobic gram-positive cocci such as enterococci, pneumococci, streptococci and staphylococci. the present investigation was undertaken to determine the in vitro activity of ly 333328 against 178 gram-positive anaerobic bacteria recently isolated from human infections. the activity was compared with that of vancomycin, teicoplanin, cefoxitin, imipenem, clindamycin and metronidazole. peptostreptococci (48 strains): ly 333 ... | 1999 | 10326737 |
| [intraocular contamination during cataract surgery according to surgical technique and type of implant]. | to determine wether the cataract extraction method and intraocular lens material affect bacterial contamination of the eye during surgery. | 1999 | 10327353 |
| bacteriostatic effects of hyaluronic acid. | this investigation is one of a series of projects seeking to ascertain whether hyaluronic acid (ha) is therapeutically effective in tissue regeneration procedures. the rationale for these investigations is to test the hypothesis that ha can serve as a bioabsorbable carrier for other substrates as well as itself actively promote the regeneration of tissue. | 1999 | 10328647 |
| localized pericarditis with calcifications mimicking a pericardial tumor. | a 62-year-old man was admitted with increasing palpitations. radiography of the chest demonstrated a calcified mass. magnetic resonance imaging revealed compression of the right ventricle by a tumor. at the time of cardiac catheterization, the coronary arteries were found not to supply blood flow of the mass, and no dip-and-plateau pattern was seen in the right ventricular pressure measurements. at the time of surgery, the mass was found to be a focal calcified thickening of the pericardium cont ... | 1999 | 10361909 |
| antibiotic sensitivity of propionibacterium acnes isolates studied in a skin clinic in singapore. | 1999 | 10376712 | |
| effect of the bacillus of calmette-guérin, propionibacter acnes and avridine as immunomodulators in antirabies vaccination of mice using the fuenzalida-palacios mouse brain vaccine. | using the laboratory mice, fuenzalida-palacios mouse brain human rabies vaccine was administered in groups of animals previously inoculated with rabies virus and then submitted to treatments with the immunomodulators onco-bcg, avridine and propionibacterium acnes. humoral and cellular immune responses were evaluated through the macrophage inhibition factor (mif), intra-pad inoculation (ipi) and serum neutralization (sn) tests and by the detection of gamma-interferon (ifn-gamma). the ipi test was ... | 1999 | 10392627 |
| [endocarditis of the native aortic valve due to propionibacterium acnes]. | 1999 | 10396160 | |
| use of a low nutrient culture medium for the identification of bacteria causing severe ocular infection. | a low nutrient culture medium was used to identify the pathogens in four cases of persisting ocular infection. bacto r2a agar was used in addition to conventional liquid- and solid-phase media to culture pathogenic bacteria from one case of recurrent keratitis, one case of suture-related keratitis with endophthalmitis and two eyes (two patients) with post-operative endophthalmitis. in each case, a pathogen was identified solely with r2a agar after culture for 6 days. species isolated were pseudo ... | 1999 | 10403423 |
| [bacterial keratitis in patients with and without contact lens anamnesis]. | the study shows differences between contact lens wearers and patients without history of contact lenses regarding the spectrum of etiological agents in bacterial keratitis. based on microbiological analysis, there are given recommendations for an optimal initial antibiotic treatment in both groups. | 1999 | 10407802 |
| quantitative pcr of mycobacterial and propionibacterial dna in lymph nodes of japanese patients with sarcoidosis. | the causes of sarcoidosis are not known. the dna of mycobacterium tuberculosis has been detected in some sarcoid lesions. in japan, propionibacterium acnes has been isolated from such lesions, but whether this indigenous bacterium is related to the disease is unclear. we used pcr to estimate the number of genomes of these bacteria in sarcoid lesions, to identify any link between sarcoidosis and these two bacterial species. | 1999 | 10408488 |
| effect of bacillus of calmette-guérin, avridine and propionibacterium acnes as immunomodulators on rabies in mice. | the cellular and humoral immune responses of mice inoculated with rabies virus and treated with the bacillus of calmette-guérin, avridine and propionibacterium acnes were evaluated in this paper. there was a higher percentage of surviving mice in groups submitted to p. acnes treatment. lower levels of interferon-gamma (ifn-gamma) were found in infected mice. the intra-pad inoculation test (ipi) was not effective to detect cellular immune response, contrary to the results found in mif reaction. t ... | 1999 | 10413958 |
| in vitro viability of external eye microbial flora in hydroxy-propyl-methylcellulose. | the aim of this study was to verify the in vitro influence of various dilutions of a viscoelastic substance containing 2% hydroxy-propyl-methylcellulose (hpmc) on the viability of some microbial strains representative of the normal flora of the external eye. pure reference strain cultures of candida albicans, pseudomonas aeruginosa, propionibacterium acnes, staphylococcus aureus, staphylococcus epidermidis and a fresh clinical isolate of proteus mirabilis were selected for this study. serial two ... | 1999 | 10420112 |
| activity of telithromycin (hmr 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology. | time-kill studies examined the activities of telithromycin (hmr 3647), erythromycin a, azithromycin, clarithromycin, roxithromycin, clindamycin, pristinamycin, amoxicillin-clavulanate, and metronidazole against 11 gram-positive and gram-negative anaerobic bacteria. time-kill studies were carried out with the addition of oxyrase in order to prevent the introduction of co(2). macrolide-azalide-ketolide mics were 0.004 to 32.0 microg/ml. of the latter group, telithromycin had the lowest mics, espec ... | 1999 | 10428930 |
| acne: a review of immunologic and microbiologic factors. | acne vulgaris is a self-limiting skin disorder seen primarily in adolescents, whose aetiology appears to be multifactorial. the four main aetiological factors are hypercornification of the pilosebaceous duct, increased sebum production, colonization with propionibacterium acnes, and subsequently the production of inflammation. considerable investigation has addressed the immunologic reaction to extracellular products produced by the acne-causing organism, p acnes. the immunologic response involv ... | 1999 | 10435165 |
| reversal of c-anca positive mesangiocapillary glomerulonephritis after removal of an infected cysto-atrial shunt. | 1999 | 10435894 | |
| [an analysis of the cause of misdiagnosis with ocular opportunistic infection]. | to evaluate the causes of misdiagnosis with ocular opportunistic infection. | 1997 | 10437001 |
| [acne vulgaris: local and systemic treatment]. | acne vulgaris is a skin disease affecting mainly young people. to its pathogenetical factors belong: excessive serum production, cornification of hair follicles and presence of different bacteria (propionibacterium acnes, staphylococcus epidermidis, pityrosporum ovale) on the skin and within hair follicles leading to skin inflammation. therapeutical approach to the patient depends on the clinical presentation of the disease. and so, in its local treatment are benzyl peroxide, azelaic acid, topic ... | 1999 | 10437405 |
| protection by a cyclic amp-specific phosphodiesterase inhibitor, rolipram, and dibutyryl cyclic amp against propionibacterium acnes and lipopolysaccharide-induced mouse hepatitis. | to study the effect of cellular camp-increasing agents on propionibacterium acnes (p. acnes) and lipopolysaccharide (lps)-induced mouse hepatitis. | 1999 | 10450787 |
| positive vitreous cultures in eyes with retained lens fragments. | 1999 | 10458307 | |
| recalcitrant acne vulgaris secondary to a dental abscess. | this case report describes a middle-aged man with acne that was recalcitrant to numerous medications, including three courses of isotretinoin. his condition cleared after an infected tooth was removed and recurred when another tooth became carious. acne vulgaris is associated with several immunologic responses including the production of antibodies against propionibacterium acnes, the gram-positive bacteria found in acne lesions. we believe that the presence of our patient's dental infections pr ... | 1999 | 10467506 |
| genus- and species-specific pcr-based detection of dairy propionibacteria in environmental samples by using primers targeted to the genes encoding 16s rrna. | pcr assays with primers targeted to the genes encoding 16s rrna were developed for detection of dairy propionibacteria. propionibacterium thoenii specific oligonucleotide pt3 was selected after partial resequencing. tests allowed the detection of less than 10 cells per reaction from milk and cheese and 10(2) cells per reaction from forage and soil. | 1999 | 10473444 |
| antibacterial activity of retinaldehyde against propionibacterium acnes. | retinaldehyde has been shown to exert antibacterial activity in vitro. | 1999 | 10473957 |
| [bacterial keratitis. microbiological analysis as a principle for therapeutic recommendations]. | the study presented differentiates between the aetiological agents of bacterial keratitis in patients with and without a history of contact lens wear. based on these results, recommendations are given for optimal antibiotic primary therapy. | 1999 | 10479898 |
| treatment strategies and visual acuity outcomes in chronic postoperative propionibacterium acnes endophthalmitis. | to report the treatment strategies and visual acuity outcomes of chronic postoperative endophthalmitis caused by propionibacterium acnes. | 1999 | 10485532 |
| microbiology of infected pustular psoriasis lesions. | bacterial infections can occur in lesions of pustular psoriasis (pp). the objective of this study was to establish the aerobic and anaerobic microbiology of secondarily infected pp. | 1999 | 10487445 |
| detection of prosthetic hip infection at revision arthroplasty by immunofluorescence microscopy and pcr amplification of the bacterial 16s rrna gene. | in this study the detection rates of bacterial infection of hip prostheses by culture and nonculture methods were compared for 120 patients with total hip revision surgery. by use of strict anaerobic bacteriological practice during the processing of samples and without enrichment, the incidence of infection by culture of material dislodged from retrieved prostheses after ultrasonication (sonicate) was 22%. bacteria were observed by immunofluorescence microscopy in 63% of sonicate samples with a ... | 1999 | 10488193 |
| acne vulgaris: state of the science. | 1999 | 10490115 | |
| [development of a vaccine for treatment of urinary tract infections]. | receiving uroinfections are predominantly treated with antibiotics and chemotherapeutics. an effective alternative treatment can be immunotherapy with inactivated bacteria. the authors have focused on the development of polybacterial vaccine with both specific and nonspecific immunostimulatory activity. the vaccine contains killed bacteria which most frequently occur as an etiological agent in urinary tract infections. determining for the selection of particular strains for the vaccine preparati ... | 1999 | 10493005 |
| jte-607, a novel inflammatory cytokine synthesis inhibitor without immunosuppression, protects from endotoxin shock in mice. | we investigated the effect of a novel n-benzoyl-l-phenylalanine derivative compound (jte-607) on production of various cytokines and other immune responses in vitro and on endotoxin shock in vivo. | 1999 | 10493164 |
| propionibacterium acnes induces acute tnfalpha-mediated apoptosis of hepatocytes followed by inflammatory t-cell-mediated granulomatous hepatitis in mice. | the cd3+/tcralphabeta+ t-cell-mediated hepatic inflammation induced by propionibacterium acnes could be divided into an acute and a chronic phase. the acute phase occurred within 72 h after injection and displayed hepatic apoptosis. anti-tnfalpha antibody inhibited both the p. acnes-induced hepatic apoptosis and lymphocyte infiltration seen in this phase, indicating the involvement of this cytokine. thereafter, a chronic phase was manifested from days 7 to 14 after injection. it was characterize ... | 1999 | 10494042 |
| gallium nitrate suppresses the production of nitric oxide and liver damage in a murine model of lps-induced septic shock. | the efficacy of gallium (ga) nitrate was examined in a murine model of sepsis. male balb/c mice (6-8 weeks) were randomized into 3 groups: 1) vehicle-treated controls 2) mice with sepsis induced by treatment with 0.3 mg i.v. of propionibacterium acnes followed one week later by 0.01 microg lipopolysaccharide (lps) and 10 mg of d-galactosamine (galn) 3) mice with sepsis injected with 45 mg/kg s.c. of gallium nitrate (calculated as elemental ga) 24 hours prior to lps/galn. two hours after lps/galn ... | 1999 | 10503955 |
| caspase-1-independent, fas/fas ligand-mediated il-18 secretion from macrophages causes acute liver injury in mice. | il-18, produced as a biologically inactive precursor, is processed by caspase-1 in lps-activated macrophages. here, we investigated caspase-1-independent processing of il-18 in fas ligand (fasl)-stimulated macrophages and its involvement in liver injury. administration of propionibacterium acnes (p. acnes) upregulated functional fas expression on macrophages in an ifngamma-dependent manner, and these macrophages became competent to secrete mature il-18 upon stimulation with fasl. this was also t ... | 1999 | 10514014 |
| pharmacokinetics and pharmacodynamics of vecuronium in rats with systemic inflammatory response syndrome: treatment with ng-monomethyl-l-arginine. | insufficient detoxification caused by nitric oxide-related inhibition of cytochrome p450 may be important for metabolism of numerous drugs, including vecuronium. the present study investigated the pharmacodynamics and pharmacokinetics of vecuronium in rats with inflammatory liver dysfunction. | 1999 | 10519503 |
| beta-hemolytic streptococci and other beta-hemolytic organisms in apical periodontitis and severe marginal periodontitis. | thirteen teeth with necrotic pulps and apical periodontitis and nine severe periodontal pockets were cultured for presence of beta-hemolytic streptococci and other beta-hemolytic organisms. samples were dispersed and plated on two non-selective and one selective growth media and incubated anaerobically and in 10% co2 in air. a total of 59 beta-hemolytic colonies were purified and identified. eight beta-hemolytic streptococcal isolates were obtained from three of the severe marginal periodontitis ... | 1999 | 10530151 |
| dexamethasone differentially regulates cytokine transcription and translation in macrophages responding to bacteria or okadaic acid. | many microorganisms and microbial products induce expression of pro-inflammatory cytokines such as interleukin-1 (il-1alpha/beta) and tumour necrosis factor-alpha (tnf-alpha) in macrophages, primarily by transcriptional activation. we show here, by using mouse macrophages in primary culture, that pre-treatment with dexamethasone inhibits bacteria-induced il-1beta expression as mrna and cellular pro-il-1beta in parallel, consistent with an effect primarily on transcriptional activation. in contra ... | 1999 | 10530874 |
| echocardiographic and survival studies in mice undergoing endotoxic shock: effects of genetic ablation of inducible nitric oxide synthase and pharmacologic antagonism of platelet-activating factor. | evidence implicating inducible nitric oxide synthase (inos) in the alterations of cardiac function characteristic of septic shock has come mostly from studies on anesthetized animals, isolated hearts, cultured myocytes, or hosts treated with pharmacologic inhibitors that lack complete specificity for inos. platelet-activating factor (paf) can participate in the induction of inos and has also been implicated in cardiac dysfunction in sepsis. the present studies assessed cardiac function in a mode ... | 1999 | 10534424 |
| digital fluorescence photography can assess the suppressive effect of benzoyl peroxide on propionibacterium acnes. | porphyrins produced by propionibacterium acnes exhibit an orange-red fluorescence under uva light. the amount of fluorescence can be estimated by digital fluorescence photography. | 1999 | 10534632 |
| [spondylodiscitis due to propionibacterium acnes. case report and review of the literature]. | propionibacterium acnes, a gram positive anaerobic organism, is a component of normal skin flora. it can exceptionally be a source of osteoarticular infection (osteitis, arthritis, spondylodiscitis). we report a case of propionibacterium acnes spondylodiscitis following lumbar puncture. this observation should alert the clinician to the fact that propionibacterium acnes may rarely cause spondylodiscitis and lumbar pain, and should be considered a causative agent of bone infections after local pr ... | 1999 | 10546305 |
| experimental liver injury induced by propionibacterium acnes and lipopolysaccharide in macrophage colony stimulating factor-deficient osteopetrotic (op/op) mice. | to clarify the involvement of growth and differentiation of liver macrophages mediated by macrophage colony-stimulating factor (m-csf) in the liver injury induced by propionibacterium acnes (p. acnes) and lipopolysaccharide (lps), we used m-csf-deficient osteopetrotic (op/op) mice. seven days after injection of p. acnes, granulomas as well as the numbers of thy-1.2-, mac-1-, and ermp-20-positive cells and f4/80-positive areas in the liver were significantly reduced in the op/op mice compared to ... | 1999 | 10548345 |
| [acne and its treatment possibilities]. | acne is a multifactorial disease affecting the pilosebaceous follicles. it is a treatable condition for which the aims of therapy are to reduce social isolation and to prevent or minimise scarring. propionibacterium acnes is an anaerobic bacterium strongly implicated in the pathogenesis of acne. a gradual increase in the resistance of p. acnes to many antibiotics has been documented in the last decade, and there is thus a growing need to use either appropriate antibiotics or even change the ther ... | 1999 | 10555254 |
| use of agar in ophthalmic pathology: a technique to improve the handling and diagnosis of temporal artery biopsies, subfoveal membranes, lens capsules, and other ocular tissues. | prospective laboratory methodology study. | 1999 | 10571345 |
| glioblastoma multiforme at the site of metal splinter injury: a coincidence? case report. | the authors report the case of a man who had suffered a penetrating metal splinter injury to the left frontal lobe at 18 years of age. thirty-seven years later the patient developed a left-sided frontal tumor at the precise site of the meningocerebral scar and posttraumatic defect. histological examination confirmed a glioblastoma multiforme adjacent to the dural scar and metal splinters. in addition, a chronic abscess from which propionibacterium acnes was isolated was found within the glioma t ... | 1999 | 10584854 |
| update on acute and chronic endophthalmitis. | 1999 | 10599651 |