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editorial: papua new guinea: medical implications of independence. 19891196181
hypnosis in medical practice.hypnosis has a role in medical practice as an adjunct to many therapies. a brief review of the history, theory, induction procedures, phenomena and practice of hypnosis is given. the use of hypnosis in the therapy of anxiety is illustrated by a report of a 44-year-old woman suffering from an aeroplane phobia.19891196183
editorial: teaching human sexuality. 19751196196
[long-term results of uretero-ileoplasty. experimental research in 8 dogs]. 19751196268
pitfalls in the diagnosis of compensable diseases in miners. 20051198247
[method for the immediate measurement of myocardial pressure velocity relationships in situ].a method for instantaneous measurements and representations of myocardial pressure-velocity relations permitting the analysis of various contractility parameters is described. basing on a modified two-element model of cardiac muscle the measurement of the relative shortening velocity vce = dp/dt(p) of the contractile elements is carried out by a special analog computer, which calculates the quotient (dp/dt) to the simultaneous left ventricular pressure p. electronic differentiation of the logari ...19751199597
chlamydial infection in women with cervical dysplasia.the prevalence of antibodies to chlamydiae, particularly to tric (trachoma-inclusion conjunctivitis) agents, was studied in women with cervical dysplasia and in women attending selected clinics (obstetrics, cancer-screening, and gynecology). in addition, attempts were made to isolate tric agents and herpesviruses from the cervices of these women. tric agent recovery rates 4.1 per cent for women with dysplasia, 5.4 per cent for pregnant women, 7.8 per cent in the women's clinic, and 0.8 per cent ...19751200069
statistical association between psoriasis and diabetes: further results.in a group of 200 psoriatic patients from the area of umbria, italy, diabetes mellitus occurred in a statistically highly significant association with psoriasis. similar observations were made earlier in a series of 600 patients. the above correlation also occurred significantly more frequently in patients under 50 years and in male patients. previous and present experience also demonstrate that psoriasis is statistically correlated with heredity for diabetes and obesity. the possible biological ...20051200712
lichen planus and ulcerative colitis.three patients with ulcerative colitis and lichen planus are reported and similar cases in the literature discussed. similarities in the pathology of the two conditions are outlined.20051201193
measurement of heparin in patients receiving subcutaneous heparin therapy.heparin assays based on four different tests of clotting function have been compared with a heparin assay utilizing the potentiating effect of heparin on anti-factor xa in a group of patients receiving subcutaneous heparin therapy during late pregnancy. it is considered that the anti-factor xa method is a better indication of the antithrombotic effect of heparin. in the presence of high levels of clotting factors, heparin assays based on tests of clotting function can be misleading.20051201205
haemoglobin c/alpha thalassaemia: haematological and biosynthetic studies.a family with genes for haemoglobin c (hb c) and alpha thalassaemia was studied. the mother had hb-c trait. the father also had hb-c trait but in addition displayed microcytosis, elevated hb-f levels and a concentration of hb-c less than usual for heterozygotes. the proband was homozygous for hb-c but had hb-f levels far exceeding those present in hb-c disease. biosynthetic studies of globin synthesis in both father and daughter showed a deficit of alpha chains relative to non-alpha chains, conf ...20051201216
comparative study of the smooth muscle contractor activity of airborne dusts and of dustiness in cotton, flax, and jute mills.a bioassay technique using isolated guinea-pig ileum was employed to compare the smooth muscle contractor activity of various dusts from mills in which the prevalence of byssinosis was known. the activity of dust from a mill spinning a coarse grade of cotton was several times greater than that in dust from a mill processing a fine grade of cotton. there was a similar order in the difference of the prevalence of byssinosis in these mills. however, the activities of fine cotton, flax, and jute dus ...19751201255
mechanism of action of adenosylcobalamin: 3-fluoro-1,2-propranediol as substrate for propanediol dehydrase--mechanistic implications.3-fluro-1,2-propanediol has been found to be a substrate for propanediol dehydrase and has very similar binding and catalytic constants compared to the natural substrate. the only isolable products of the reaction are acrolein and inorganic fluoride; with 3-fluoro-3,3-dideuterio-1,2-propanediol as substrate, only 3,3-dideuterioacrolein is obtained. these results indicate that the primary product of the reaction is 3-fluoropropionaldehyde which spontaneously loses hydrogen fluoride to yield acrol ...20051201278
trachoma in the sudan. a laboratory study.out of 46 patients in the sudan who had been diagnosed clinically as having trachoma 25 strains of the trachoma agent were isolated. bacterial contamination was easily controlled by streptomycin and vancomycin. on repeated passaging, chick embryos lost their susceptibility to the trachoma agent during the summer.19751203228
[is appendicitis still a problem in our health services?]. 20051214553
chlamydial eye disease.in the united states, chlamydial (tric) agents cause a small but important segment of infectious ocular disease. elsewhere in the world, trachoma still represents the single greatest cause of blindness. the description of these diseases in this chapter is a brief introduction to a subject about which volumes have been and will continue to be written. barring unforeseen developments, these agents will continue to plague humankind beyond the end of the twentieth century.19751225860
[active searching for information in german and american children]. 19981228739
[models of behavior]. 20051230915
["false aggravation" of the eeg in the days following cranial trauma in the child]. 20051230927
[inmediate and late intubation and tracheostomy lesions (author's transl)]. 20051230933
[dynamics of functional disorders of the upper urinary tract]. 20051231110
[influence of endogenous factors on the ash, calcium, magnesium, potassium, sodium, phosphorus, zinc, iron, copper and manganese contents in the bristles of pigs. 3. influence of time of cutting on the mineral composition of the hair (boar bristles)].the ash content and the content of ca, mg, k, and na in the bristles of pigs is influenced by the age of the animal and by the season of the year. the peak concentrations of ash, ca and mg in the bristles of eight boars (cut every month) were found in june, shortly before the change in hair coat. (p less than 0.05-0.001). the concentrations of k and na in the bristles deviated functionally from the change in the hair coat. in the first half of the year the bristles of the boars contained signifi ...19751233935
end result of the surgical treatment for advanced stomach carcinoma [proceedings]. 20051234100
pathological fractures in echinococcosis of bone. 20051234118
the effects of acute infection on blood lead, copper, and zinc levels in children.recent reports in the literature have presented results showing a decrease in blood zinc levels accompanied by an increase in blood copper levels during acute infection. the purpose of this study was to determine possible shifts in whole blood lead as well as whole blood zinc and copper during such a stress state. the total survey population of 73 was divided into 21 children with non-infectious diseases, 40 children with acute infections and 12 asymptomatic lead poisoned children admitted for e ...20051236615
evaluation of laboratory management training.the purpose of this study was to determine if motivation to manage increased simultaneously with planned-for cognitive learning of management. a management course designed to stimulate cognitive learning was studied. it was presented to supervisors in hospital, independent, and public health laboratories. two groups of 22 and 26 participants, respectively, were identified to be studied. measures of cognition and motivation were taken before and after training. the analysis revealed statistically ...20051236624
laboratory procedures for the isolation of chlamydia trachomatis from the human genital tract.the technique of isolating chlamydia trachomatis from the human gential tract by centrifuging clinical specimens on to cell monolayers with subsequent incubation has been improved and simplified. gentamicin in the media was found to be superior to streptomycin in reducing bacterial contamination of specimens. the infectivity of chlamydial suspensions of laboratory cultured material was significantly reduced by storage at +4 degrees c for more than 48 hours, and by immediate freezing to -70 degre ...19751236632
numerical analysis and computerized identification of the yeast genera candida and torulopsis.numerical analysis of the published standard descriptions of 104 species of candida and 48 species of torulopsis suggested that the number of species should be reduced to 78 and 33 respectively. four examples are noted of closely matched species differing in ability to assimilate nitrate; these species may be combined as nitrate-variable species. although the ability to form pseudomycelium is the only important difference between the genera, only three examples were noted of candida and torulops ...19751236931
[clinical and etiological studies of glucocorticoid-reactive hypertension]. 20051236988
comparative infectivity of trachoma organisms in hela 229 cells and egg cultures.thirty-two trachoma strains were simultaneously titrated in the yolk sac of embryonated chicken eggs and in hela 229 cells pretreated with diethylaminoethyl-dextran to determine the relative sensitivity of the two culture systems for detection of the infection. the strains tested were both yolk sac- and hela cell-established isolates from the eye and the genital tract. the study showed that the cell culture was of equal or greater sensitivity than yolk sac culture and that ocular and genital iso ...19751238370
[pathological study of wegener's granulomatosis - with special reference to pathological changes of the respiratory organs]. 19941238812
rheumatoid arthritis of the cricoarytenoid joints: an airway hazard.the anesthesiologist must maintain a high index of suspicion for the presence of cricoarytenoid arthritis and vocal-cord fixation in the rheumatoid arthritic. he must be prepared to intubate the trachea blindly, attempting to minimize trauma by using a smaller endotracheal tube. indirect laryngoscopy, or direct laryngoscopy using a fiberoptic laryngoscope, may be indicated as part of the preanesthetic evaluation. in some instances, preanesthetic tracheostomy or an alternative regional anesthetic ...19951239211
some metabolic and biochemical characteristics of representative microbial isolates from vacuum-packaged beef. 19751239440
cd spectral comparison of porcine proinsulin c-peptide and several fragments of its sequence. 19751240088
studies of trachoma in families on taiwan.this study was undertaken to clarify the natural history and pathogenesis of trachoma. a group of families who live in a formerly trachoma hyperendemic area of southern taiwan were placed under continuous surveillance. the development in recent years of the micro immunofluorescence test for trachoma antibody, along with improved cell culture isolation methods, have allowed this surveillance to include repeated effective laboratory studies in addition to clinical observations. after four years' s ...19751243110
trachoma organisms: technical advances in laboratory diagnosis.new knowledge of the microbiology and immunology of chlamydia is reviewed. new serological and isolation methods for diagnosis of trachoma infection are described. results of studies of ocular and genital trachoma infection utilizing these new techniques are presented.19751243119
a "pseudotumor" of the stomach. 19871245800
problems in abdominal surgery. i. peritoneovenous shunting for intractable ascites. 20051246076
letter: radiation from smoke detectors. 19871246324
letter: standardization of heparin-lock maintenance solution. 19871246325
cardiovascular abnormalities associated with congenital diaphragmatic hernia.cardiovascular abnormalities were present in 11 of 48 (23%) patients with congeital diaphragmatic hernia. cardiac abnormalities included congenital heart disease, compression of a major vascular structure, cardiac malposition, and abnormalities in pulmonary circulation. the differential diagnosis between isolated congenital diaphragmatic hernia and coexisting cardiac abnormality may be difficult and may require echocardiographic or invasive studies. mortality in infants with diaphragmatic hernia ...19871246507
generalized lymphadenopathy and nephrotic syndrome as a manifestation of mephenytoin (mesantoin) toxicity.this report describes a patient who developed marked generalized adenopathy and nephrotic syndrome while receiving mephenytoin (mesantoin) for a seizure disorder. renal biopsy showed a diffuse proliferative glomerulonephritis. lymph node histopathology revealed replacement of parenchyma with lymphocytes, eosinophils, and reticuloendothelial cells. a hypersensitivity reaction is postulated as the etiology of both these processes.19871246508
computerized axial tomography. 19871246994
purification and properties of formaldehyde dehydrogenase and formate dehydrogenase from candida boidinii.formaldehyde hydrogenase and formate dehydrogenase were purified 130-fold and 19-fold respectively from candida boidinii grown on methanol. the final enzyme preparations were homogenous as judged by acrylamide gel electrophoresis and by sedimentation in an ultracentrifuge. the molecular weights of the enzymes were determined by sedimentation equilibrium studies and calculated as 80000 and 74000 respectively. dissociation into subunits was observed by treatment with sodium dodecylsulfate. the mol ...20051248477
the effects of cocaine and diphenhydramine upon the reactivity of rat vas deferens to supramaximal doses of noradrenaline and of other agonists: the mode of action of cocaine.the effects of cocaine on responses to supramaximal concentrations of agonists have been studied in preparations of rat vas deferens. cocaine 10 mum decreased the mean time to peak and increased the mean magnitude of responses to noradrenaline but not to supramaximal field stimulation of sympathetic fibres, to high potassium or to methoxamine. diphenydramine 10 mum affected responses to noradrenaline similarly. it is proposed that the prejunctional action of cocaine and of diphenhydramine to red ...19761248509
formation of bundles of microfilaments during spreading of fibroblasts on the substrate. 20051248516
the nucleoli of cultured human lymphocytes. i. nucleolar morphology in relation to transformation and the dna cycle. 19761248517
the serum dependence of baby hamster kidney cell attachment to a substratum. 20051248519
effects of deafferentation on the development of the isthmo-optic nucleus in the duck (anas platyrhynchos). 19761248537
[transthoracic truncal vagotomy as an operation necessary in peptic ulcer of the jejunum].peptic ulcers require radical surgery in most cases, typically involving resection of the gaster and a vagotomy. however, as post partial gastrectomy recidive peptic ulcers are usually recistant to internal treatment, and since often patients so afflicted are in poor physical condition, the surgeon must choose the least radical procedure. because of this, the authors feel that in cases of perforative and/or bleeding peptic ulcers of the jejunum, the transthoracic truncal vagotomy in the procedur ...20051251668
fluorosis in black-tailed deer.marked dental disfigurement and abnormal tooth wear patterns were observed in black-tailed deer (odocoileus hemionus columbianus) taken from an area near an industrial fluoride source in northwestern washington. fluoride levels in the bones of these deer were from 10 to 35 times higher than levels in the bones of normal animals. these levels are similar to those associated with fluorosis of cattle.19761255910
the immune response of rabbits to 3 strains of mycoplasma agalactiae var. bovis isolated from mastitic bovine udders.rabbits were given 3 serologically-related trains of mycoplasma isolated from mastitic bovine udders. growth inhibiting antibodies were not found. high-titered sera from each rabbit immunized with each strain developed at least 4 precipitin lines to each organism and at least one line of identity was demonstrated between the organisms. significant indirect hemagglutination titers were found in all rabbits in 1 week, with titers reaching 1.0 x 10(5) to 3.3 x 10(5) in 4 to 6 weeks but despite cont ...19761261267
photocyclization of diethylstilbestrol. isolation of a stable, self-trapping dihydrophenanthrene intermediate. 20041262645
the detection of antibodies in human and animal filariases by counterimmunoelectrophoresis with dirofilaria immitis antigens.counterimmunoelectrophoresis revealed the presence of precipitin antibody in all of 6 dogs and the 1 cat infected with dirofilaria immitis and in the serum of 17 of 24 individuals living in a setting of hyperendemic subperiodic bancroftian filariasis. antigens used in the test were prepared from microfilariae and adult male d. immitis. some humans and animals had antibodies to both antigens while others had antibodies against microfilariae or adult worms only. the presence of soluble circulating ...19761262695
attenuated, streptomycin-dependent salmonella typhi oral vaccine: potential deleterious effects of lyophilization.four studies were done with streptomycin-dependent salmonella typhi as an oral, attenuated vaccine. studies 1 and 3 employed freshly harvested vaccine, whereas studies 2 and 4 involved lyophilized vaccine. five to eight doses (3 x 10(10)-10(11) organisms/dose) were given; oral streptomycin (1.0 g) was administered concomitantly in studies 2 and 3, with only two of the doses of vaccine in study 1, and was not given in study 4. no adverse reactions were encountered in 179 vaccinated men, and 94% o ...19761262709
training of family practitioners in high gear. 20051262719
pap smears in primary medical office practice: a review and reevaluation. 20051262738
[editorial: estrogen analysis during pregnancy]. 20051265909
[proceedings: hepatitis b antigen, hepatitis d antibodies and botevgrad antigen in liver diseases]. 20041266175
[sexual medicine treatment in the practice of the health-insurance physician]. 20051266350
letter: prevention of coronary heart disease. 19891268626
activity-related increases of glucose utilization associated with reduced incorporation of glucose into its derivatives. 19761268751
observations on the localization of recently synthesized catecholamines in chromaffin cells after the injection of l-(2,5,6-3h)dopa.the fate of tl-[2, 5, 6-3h] dopa, and the intracellular localization of its metabolic products dopamine, noradrenaline and adrenaline, have been determined by the simultaneous use of assay techniques following separation of amines by chromatography and light and electron microscopic autoradiography. during the first 24 h after i.v. or i.p. injection of [3h] dopa, synthesis of the above catecholamines occurred. throughout this time the labelled amines were associated with chromaffin granules or i ...20051270951
[clinical use of polyglycol threads]. 20051272993
[complex psychophysiological evaluation of the occupational fitness of the command personnel of marine vessels]. 20051274253
health care development as an agent of change. 20051274331
severe endemic trachoma in tunisia.in two villages in southern tunisia where trachoma was endemic 7 per cent and 14 per cent of adults respectively had visual acuity of 20/400 or less. in both villages active trachoma affected most children under the age of two, reached a peak in two- to five-year-olds, then declined to age 15. the chronic inflammatory disease in childhood appeared to produce irreversible scarring of the eyelids, and loss of vision occurred in adult life due to corneal scarring caused by inturned eye lashes and l ...19761276112
register of psychiatrists in training. 20051276791
the relationship between anamnestic factors and the course of schizophrenia. 20051277815
the characterization of nonbacterial prostatitis: search for an etiology.nonbacterial prostatitis is often difficult to differentiate from other prostatic complaints and remains a vaguely characterized syndrome. prostatic fluid inflammatory cells and elevated immunoglobulins raise the suspicion that this syndrome is caused by some undetected infection. prostatic fluid antibodies against chlamydia trachomatis, ureaplasma urealyticum, staphylococcus, staphylococcus faecalis, bacteroides fragilis and clostridium perfringens were measured in men with nonbacterial and bac ...19921279213
azithromycin-induced block of elementary body formation in chlamydia trachomatis.the mechanism of action of azithromycin on the murine strain of chlamydia trachomatis grown in tissue culture epithelial cells is addressed. azithromycin at a concentration of 100 ng/ml inhibits chlamydial growth in tissue culture, a value that agrees well with prior in vitro data from human strains of c. trachomatis grown in tissue culture. by morphological criteria, the block to chlamydial growth appears to occur early in its life cycle. azithromycin is not directly toxic to chlamydial element ...19921280057
structural and functional aspects of rna pseudoknots. 20051280160
inhibitory effects of pectic substances on activated hyaluronidase and histamine release from mast cells.in this paper, we report the effect of pectic substances and d-galacturonic acid, the main constituent of pectic substances, on activated hyaluronidase and histamine release from mast cells. although d-galacturonic acid itself showed no inhibition, ic50 values of hyaluronidase inhibition were correlated with the d-galacturonic-acid content of pectic substances. it was thought that the polymerization of d-galacturonic acid was necessary for inhibition of activated hyaluronidase. this type of inhi ...19921280162
melioidosis: when in doubt leave the quinolone alone! 19921280318
azithromycin. a review of its antimicrobial activity, pharmacokinetic properties and clinical efficacy.azithromycin is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin, with a similar spectrum of antimicrobial activity. azithromycin is marginally less active than erythromycin in vitro against gram-positive organisms, although this is of doubtful clinical significance as susceptibility concentrations fall within the range of achievable tissue azithromycin concentrations. in contrast, azithromycin appears to be more active than erythromycin again ...19921280567
infection with a plasmid-free variant chlamydia related to chlamydia trachomatis identified by using multiple assays for nucleic acid detection.clinical samples in transport media from 40 patients exhibiting pathologies potentially caused by chlamydia trachomatis infection were analyzed for chlamydial nucleic acid, and the results were compared with those of culture. chlamydial culture was performed by a shell vial centrifugation method with hela 229 host cells. polymerase chain reaction (pcr) assays were used to detect either regions on a 7.5-kb plasmid characteristic of c. trachomatis (plasmid-pcr) or a segment of the 16s rrna genes ( ...19921280642
convergent and overlapping transcripts of the chlamydia trachomatis 7.5-kb plasmid.transcription of the 7.5-kb cryptic plasmid of chlamydia trachomatis serovar l2 was investigated. faint, diffuse transcripts of about 1.6 and 2.2 kb and intense short transcripts of about 250 and 430 bases were identified by northern blot analysis. the short transcripts were found to have a common 5' end corresponding to bp 501 relative to the unique bamhi site of the plasmid and to terminate at different downstream sites. putative promoter sequences of ttgcca and tatatt, which closely resemble ...19921281330
evidence for a role of the neuropeptide galanin in spatial learning.the neuropeptide galanin coexists with acetylcholine (ach) in the basal forebrain cholinergic neurons and modulates cholinergic activity in the forebrain. the cholinergic forebrain neurons appear to play a significant role in learning and memory, as suggested by a severe loss of these neurons in alzheimer's disease. the involvement of endogenous galanin in learning is demonstrated here by the use of the recently synthesized high-affinity galanin antagonist m35 [galanin(1-13)-bradykinin(2-9) amid ...19921281521
mutagenicity testing of imidazole and related compounds.ames tests have been performed with imidazole and its principal metabolites, hydantoin and hydantoic acid. n-acetyl-imidazole, a potential metabolite resulting from the action of intestinal bacteria, and histamine, a structurally related compound which is widely distributed in mammalian tissues, have also been tested. imidazole and histamine were also tested in the uds assay in primary rat hepatocytes, while imidazole alone was tested in the m2-c3h mouse fibroblast malignant transformation assay ...19921282214
binding of chlamydia trachomatis serovar l2 to collagen types i and iv, fibronectin, heparan sulphate, laminin and vitronectin.chlamydia trachomatis serovar l2 elementary bodies were tested for binding to 125i-labelled components of the extracellular matrix. c. trachomatis bound high levels of collagen type i and heparan sulphate, whereas the binding to collagen type iv, fibronectin, laminin and vitronectin was substantially less. preliminary characterization showed that chlamydial surface proteins are essential for binding to occur. our results suggest that a selective affinity for c. trachomatis to a limited number of ...19921283091
sexually transmitted diseases in england and wales: 1981-1990.data provided by genito-urinary medicine clinics, microbiology laboratories and other reports reveal a consistent picture of the epidemiology of sexually transmitted diseases in england and wales during the 1980s. the number of new cases increased by 21% between 1981 and 1990; most of this increase being due to genital herpes, genital warts and 'non-specific genital infection' (including that due to chlamydia trachomatis). the increase in attendance rates for new cases was much higher for women ...19921285223
prevalence of urogenital chlamydia trachomatis infection in el salvador. ii. gynaecology outpatients.the prevalence of urogenital infection caused by chlamydia trachomatis was examined in 100 non-pregnant women with cervicitis, and 100 healthy women, in san salvador city, el salvador. pharmacia chlamydia eia test was used for the detection of chlamydial antigen in urethral and cervical specimens from all the women. direct immunofluorescence was used for confirmative tests on the eia positive and the negative gray zone samples. c. trachomatis antigen was detected in 28% of the women with cervici ...19921286120
the role of the laboratory in a chlamydia control programme in a developing country.the laboratory components of a chlamydia trachomatis disease control programme for a developing country are reviewed. early diagnosis of chlamydial infections is the most cost effective means of preventing the long term sequelae of trachoma, pelvic inflammatory disease, ectopic pregnancy and infertility, which are now a major public health burden to the health care system in developing countries. public health strategies are required to establish both a co-ordinated limited system of laboratory ...19921286634
who gets care? access to health care as an arena for nursing action.access to health care in the united states is undeniably inequitable. what should nurses do in the face of increasing gaps in availability of services? the author addresses this question by framing access to health care in its broadest sociopolitical context, positing that access to care is an essential dimension of nursing theory, research, and practice. by offering a conceptual definition of equitable access, providing rationale for the significance of this concept, and critically exploring co ...20051287782
increased rate of survival in streptococcus pneumoniae-infected rats treated with the new immunomodulator pidotimod.wistar rats infected with streptococcus pneumoniae (type iii atcc) rapidly develop an acute form of experimental lobar pneumonia (elp) with death of 80-90% of the animals by 6 days after the infection. prophylactic treatment of these animals with the novel immunomodulator pidotimod, at the dose of 25 mg/kg bw, significantly increased their rate of survival as compared to the control group (50 vs. 90% respectively). recovery from the infection appeared definitive since all the pidotimod-treated s ...19921287821
maze-running and thigmotaxis in mice: applicability of models across the sexes.both male (n = 244) and female (n = 223) swiss albino mice displayed a u-shaped pattern of thigmotaxis (wall-seeking) in a circular open-field (of) before and after a daily maze-running. a significant increase of mice's tendency to occupy the inner partitions of the of after the maze trial on the last three out of five days of training was observed. when factor analyzed, the variables indicating the wall-seeking behaviour of both sexes were divided into two factors interpreted as "spontaneous" i ...20051287829
chloroquine-resistant plasmodium falciparum isolates from the sudan lack two mutations in the pfmdr1 gene thought to be associated with chloroquine resistance.isolates of plasmodium falciparum from 3 areas of the sudan were recovered from cryopreservation in london and their chloroquine sensitivity was determined in vitro. chloroquine resistance was detected in 6/6 isolates from khartoum, 1/4 from sennar and 3/3 from gadarif, indicating that resistance is spreading. all the isolates were sensitive to mefloquine. studies using blood spots on glass fibre discs and the polymerase chain reaction did not detect two mutations in the pfmdr1 gene, thought to ...19921287907
chlamydial infections in selected populations in jamaica.the importance of chlamydia trachomatis as a cause of genital tract infection in caribbean countries is largely unknown. two hundred and sixteen cervical and urethral specimens were collected from patients with cervicitis and urethritis attending a sexually transmitted diseases (std) clinic, a gynaecology clinic and a family planning clinic in kingston. specimens were tested for chlamydiae by direct immunofluorescence and cell culture methods. they were also investigated for n. gonorrhoeae infec ...19921290231
[uses of vaginal ph measurement for prevention of premature labor. results of a prospective study].the influence of the microflora of the vagina and cervix has been undervalued for the induction of premature birth. examination of the microbiological problem by determination of the vaginal ph in combination with the microflora (chlamydia trachomatis, mycoplasma hominis, ureaplasma urealyticum). report of the outcome of 161 prospective, ad the beginning normal pregnancies in comparison of 200 primary hospitalized pregnancies with symptoms of imminent premature birth. conclusion: the vaginal ph ...19921290278
laboratory reports of human viral and selected non-viral infections in canada--1991. 19921291004
toxicology versus allergy in restorative dentistry.the frequency of side-effects among dental patients is very low and is seen mostly as mild allergic reactions. among the dental staff, contact allergic eczema is occasionally seen, induced by certain metals and various organic materials.19901292456
[comparison of polymerase chain reaction and ideia chlamydia in detection of chlamydia trachomatis from first-voided urine of male urethritis patients].we have reported a method for detection of chlamydia trachomatis by polymerase chain reaction (pcr) with two oligonucleotides based on sequences within the major outer membrane protein gene from c. trachomatis serovar l2. in the previous report, in addition to treatment of the mixture of first-voided urine (fvu) sediment and 1 ml of urine with proteinase k. dna purification by phenol extraction was necessary for preparation of template dna for pcr. in this study, fvu sediment was suspended in 1 ...19921293226
iga antichlamydia antibodies as a diagnostic tool for monitoring of active chlamydial infection.chlamydia trachomatis isolation in culture is the best means of chlamydial infection diagnosis. antichlamydial antibodies, if present, may also serve as diagnostic markers. in eleven patients with positive c. trachomatis culture and serological positive response, specific iga and igg antibody titers were measured before and after treatment. in all cases, cultures became negative after treatment and iga titers decreased rapidly, while igg levels remained high. thus, presence of specific iga antib ...19921294398
intracellular accumulation of free calcium in mouse tumor cells exposed to anticancer drugs.alterations in concentrations of intracellular free calcium ([ca2+]i) were examined in mouse sarcoma s-180 cells exposed to cisplatin, mitomycin c and adriamycin, as related to cell viability. the [ca2+]i was measured using the fluorescent ca2+ indicator, fura-2. during the first 24 hr of incubation of the cells in vitro, in the presence of the drugs, the [ca2+]i was lower than in the control cells. after 24 hr of incubation, the [ca2+]i began to increase at a time when the cell viability was re ...19921295467
detection of igm antibodies to chlamydia trachomatis, chlamydia pneumoniae, and chlamydia psittaci from japanese infants and children with pneumonia.chlamydia trachomatis (c. trachomatis) is now well established as a pathogen of neonatal inclusion conjunctivitis and infantile pneumonia. c. pneumoniae (twar) and c. psittaci also cause pneumonia and other respiratory infections. serum samples from 223 japanese infants and children with pneumonia were tested for igm antibodies to c. trachomatis, c. pneumoniae and c. psittaci. igm antibodies to c. trachomatis were measured by an enzyme immunoassay (eia) and by a microimmunofluorescence (mif) tes ...19921296808
developmental regulation of globin gene expression.we have used the globin family of genes in chicken to study developmental regulation of gene expression, both at the level of individual interaction of trans-acting factors with local promoters and enhancers, and at the level of chromatin structure. regulation of all members of the alpha- and beta-globin clusters is affected by the erythroid regulatory factor gata-1. separate mechanisms exist for regulation of individual members of the family. as an example, we describe the control mechanisms th ...19921297648
dna fingerprinting of chlamydia trachomatis by use of ribosomal rna, oligonucleotide and randomly cloned dna probes.dna fingerprinting of 15 reference strains and 24 clinical isolates of chlamydia trachomatis, 2 strains of c. psittaci and one strain of c. pneumoniae was studied by use of universal 16 + 23s rna from escherichia coli, 16s rdna-directed oligonucleotide and randomly cloned chlamydial dna probes. the rrna-gene restriction patterns (ribotypes) enabled the differentiation of chlamydial species. following dna cleavage by restriction endonuclease pvuii, lymphogranuloma venereum and trachoma biovars of ...19921298028
construction and implementation of qrst-wave simulation model.computer simulation study of the electrical activity of the heart is one of the frontier subjects of electrocardiogram (ecg) theory study. a new algorithm for simulating excitation propagation within the heart is presented in this paper. on the basis of this, computer simulation of qrst-wave is completed on an ibm pc microcomputer. all performance of the model is compared favourably with that of the models implemented on main frames or on high-performance work stations abroad.20051298293
percutaneous ultrasound guided cholecystostomy with double bubble catheter.we have used a prototype double bubble cholecystostomy catheter in four very ill patients. this has been done under local anaesthetic using a seldinger technique, ultrasound guidance, and a trans-peritoneal approach to the gallbladder. the catheter provides drainage, cholangiography, and is intended to allow instrumentation of the biliary tract at a later stage.20041299194
glucose-6-phosphate dehydrogenase (g6pd) deficiency in the albanian ethnic minority of cosenza province, italy.the albanian ethnic minority of the cosenza province (calabria, southern italy) is constituted by a population of 42,305 inhabitants living in 19 communes. the first presence of this population, in southern italy, dates back to the fifteenth century as a result of different immigrations. we have studied the g6pd in the population of this province by determining both the frequency of the g6pd-deficiency and the type of gd(-) alleles in samples from 19 communes. the overall frequency estimate turn ...20051299317
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