Publications

TitleAbstractYear
Filter
PMID(sorted ascending)
Filter
salmonella enterica subspecies diarizonae bacteremia in an infant with enteritis--a case report.the septicemia caused by the arizona group organism is rare and usually observed in adults with underlying diseases. in korea, salmonella infection is common, but a report of arizona infection is unknown. we isolated s. entercia subsp. diarizonae from blood of a 6-month-old infant. the serovar was determined as 28:z10:-, a rare one in america. the isolate was susceptible to ampicillin, chloramphenicol, cotrimoxazole and others. the patient rapidly recovered with ampicillin and gentamicin therapy ...19911781188
salmonella enterica subspecies diarizonae bacteremia in an infant with enteritis--a case report.the septicemia caused by the arizona group organism is rare and usually observed in adults with underlying diseases. in korea, salmonella infection is common, but a report of arizona infection is unknown. we isolated s. entercia subsp. diarizonae from blood of a 6-month-old infant. the serovar was determined as 28:z10:-, a rare one in america. the isolate was susceptible to ampicillin, chloramphenicol, cotrimoxazole and others. the patient rapidly recovered with ampicillin and gentamicin therapy ...19911781188
illumination and errors in dispensing.the relationship between the level of illumination and the prescription-dispensing error rate in a high-volume army outpatient pharmacy was investigated. the prescription error rate was determined by direct, undisguised observation and retrospective prescription review under three levels of illumination (45, 102, and 146 foot-candles) during 21 consecutive weekdays. illumination was controlled in the prescription-checking area of the pharmacy by using additional fluorescent lamps and filters. th ...20071781468
compatibility of ciprofloxacin injection with selected drugs and solutions.the compatibility of ciprofloxacin injection with selected antimicrobials and aminophylline was studied. ciprofloxacin, amikacin sulfate, aminophylline, clindamycin phosphate, gentamicin sulfate, and tobramycin sulfate were mixed separately in minibags containing 0.9% sodium chloride injection or 5% dextrose injection; admixtures were stored for up to 48 hours at either 4 degrees c or 25 degrees c. ciprofloxacin was also combined separately with each of the other drugs and solutions and stored u ...20071781473
damage to hepatic thyroxine 5'-deiodination induced by pathogenic factors of keshan disease and the preventive effects of selenium and vitamin e.experiments were performed to investigate the change of hepatic t4 5'-deiodination and the preventive effects of selenium (se) and vitamin e in rats fed grains from a keshan disease (kd) endemic area. the results showed that consumption of the endemic grain for 8 weeks caused a significant reduction in hepatic t4 5'-monodeiodinase and glutathione peroxidase activities, and a marked enhancement of hepatic malondialdehyde content. these changes could be effectively prevented through se or vitamin ...19911781930
metabolic patterns associated with non-specific magnetic resonance imaging abnormalities in temporal lobe epilepsy.we investigated the cerebral metabolic patterns associated with non-specific hyperintense t2-weighted image on magnetic resonance imaging (mri) in temporal lobe epilepsy (tle). nineteen patients suffering from tle with a normal ct scan underwent positron emission tomography (pet) using 18f-fluorodeoxyglucose; 8 had hyperintense t2-weighted image on mri in the epileptogenic temporal lobe and 11 had a normal mri. interictally, pet exhibited focal hypometabolism in all the patients with hyperintens ...20041782521
differential impact of right and left hemisphere lesions on facial emotion and object imagery.thirty-six patients with unilateral hemispheric lesions of the right hemisphere (rhd), left hemisphere (lhd), or no neurologic disease were evaluated on two tasks of visual imagery: one involved imagery for facial emotions and the other involved imagery for common objects. as a group, the rhd patients were more impaired on the emotional than the object imagery task, whereas the lhd patients showed the opposite pattern. individual case analyses suggested that the rhd group consisted of different ...20041782533
[efficiency evaluation of combined intervention measures with improving drinking water first to prevent infantile acute diarrhea].the paper analysed factors of acute diarrhea in children under five by mantel-haenszel stratification and logistic regression. the total person-years of observation were 1332. the results showed that the combined risk factors which caused diarrhea were drinking the pond water and failure to wash hands before eating and so on. the combined intervention measures, especially improvement of drinking water had effectively decreased the incidence rate of infantile acute diarrhea through the observatio ...20021782659
effect of intracanalicular collagen implants on the absorption of topically applied sodium fluorescein.absorbable intracanalicular collagen implants were placed in both canaliculi of one eye of nine human volunteers. the other eye served as a control. twenty-four hours later 2% sodium fluorescein was placed into both conjunctival sacs. serial corneal fluorescein concentrations were measured with a scanning ocular fluorophotometer from 2 to 90 min after fluorescein administration. the mean corneal fluorescein concentration averaged over all time points was greater in 7 of 9 eyes with collagen impl ...19911782780
coronary artery thrombosis and thrombolysis in baboons: the effect of atenolol treatment on myocardial infarct size.the effect of the beta-blocker atenolol on experimental infarct size was studied in a non-human primate model. in 12 baboons thrombosis of the left anterior descending coronary artery (lad) was induced and atenolol (0.1 to 0.2 mg.kg-1 intravenously, sufficient to lower the heart rate by 20%) was administered 10 min after the onset of ischaemia in six animals, whereas the others received placebo. thrombolysis was induced 60 min after the onset of ischaemia by intravenous injection of rtpa (12 mic ...19911782934
changes of anti-hb core antibody in children with positive hb surface antigen.to elucidate the clinical courses of children chronically infected with hb virus (hbv), ria values of anti-hbc were surveyed in 88 cases with positive hbs antigen. among 56 children with positive hbe antigen, 20 had negative, indefinite or low titers of anti-hbc, and 18 (90%) of them had no liver malfunction. out of 30 cases with abnormal liver function tests, 28 (93%) had high titers of anti-hbc. follow-up study for a period of over 12 months reveals that serum hbe antigen disappeared in 10 out ...19911785326
[the culture of discussions and a little bit on the epidemiology of intestinal infections]. 19911789044
["the modern theoretical and practical concepts of the epidemiology of shigellosis" and the culture of discussions]. 19911789045
[continuous noninvasive recording of circulatory parameters while performing the valsalva test under elevated ambient pressure].the results are presented which confirm applicability of the valsalva test as a functional exercise for the cardiovascular system while studying changes of the circulation regulation under high ambient pressure. methods of transthoracic tetrapolar impedance plethysmography, electro- and intervalocardiography and mean arterial pressure measurement by means of the oscillometric servosystem are shown as adequate and highly informative under these conditions.20051790814
sequence variation in two ipah genes of shigella flexneri 5 and homology to the lrg-like family of proteins.oligonucleotide primers derived from the ipah7.8 sequence have been used to determine the boundaries of dna sequence homology among five ipah genes on the invasion plasmid (pwr100) of shigella flexneri 5, strain m9ot-w. the primary structure of ipah4.5 has been established from dna sequence analysis. the first 197 amino acids in ipah7.8 were replaced in ipah4.5 by a unique set of 251 amino acids, generating two related proteins with variable and conserved sequences. the amino-terminal region of ...19911791758
[the characteristics of the course of typhoid-paratyphoid diseases combined with acute dysentery]. 19911792774
lauryl sulphate haemoglobin: a non-hazardous substitute for hicn in haemoglobinometry.the haemiglobincyanide (hicn) method for measuring haemoglobin is used extensively worldwide; its advantage is the ready availability of a stable and internationally accepted reference standard/calibrator. however, its use may create a problem, especially in automated analysers, as the waste disposal of large volumes of reagent containing cyanide may constitute a potential toxic hazard. as an alternative, conversion of haemoglobin to a sulphate derivative by nontoxic sodium lauryl sulphate has b ...20071794230
on the regulation of collagen-fibril shape and form. 20061794563
[plasmid analysis of antibiotic resistant shigella isolates].a correlation between the multiple drug resistance patterns and the plasmid profiles given by 70 clinical isolates of shigella sonnei and shigella flexneri was investigated in this study. the most common plasmids were purified from different isolates by electroelution and characterized via restriction endonuclease digestions.19911795658
[bacillary dysentery--1989]. 19911796165
continuous spinal anesthesia with hyperbaric and isobaric bupivacaine. 20061796979
continuous spinal anesthesia with hyperbaric and isobaric bupivacaine. 20061796979
excretion of urinary enzymes in female sprague-dawley rats in relation to cellular compartment, creatinine excretion and diuresis.one hundred and one young-adult female sprague-dawley rats were acclimatized to metabolic cages for 2 days. after that time 24-hour urine was collected at a constant cooling temperature of 0-4 degrees c. after gel filtration the enzyme activities were determined, and the resulting values were used to calculate 24-hour excretions. the following reference ranges (2.5 and 97.5 percentiles) were determined (in mu/24 h): lactate dehydrogenase 43-181; phosphohexoseisomerase 45-1445; glutathione-s-tran ...19911797103
excretion of urinary enzymes in female sprague-dawley rats in relation to cellular compartment, creatinine excretion and diuresis.one hundred and one young-adult female sprague-dawley rats were acclimatized to metabolic cages for 2 days. after that time 24-hour urine was collected at a constant cooling temperature of 0-4 degrees c. after gel filtration the enzyme activities were determined, and the resulting values were used to calculate 24-hour excretions. the following reference ranges (2.5 and 97.5 percentiles) were determined (in mu/24 h): lactate dehydrogenase 43-181; phosphohexoseisomerase 45-1445; glutathione-s-tran ...19911797103
unconjugated and conjugated bilirubin pigments during perinatal development. iii. studies on serum of breast-fed and formula-fed neonates.the process of conjugation and secretion of bilirubin was studied in a group of healthy, full-term, exclusively breast-fed newborns and a control group of exclusively formula-fed infants by means of a reverse-phase high-performance liquid chromatographic analysis of bilirubins present in serum. the serum concentrations of unconjugated bilirubin, esterified bilirubin, and the proportion of diesterified bilirubin (as percent of esterified bilirubin) were not significantly different in breast- and ...19911797114
unconjugated and conjugated bilirubin pigments during perinatal development. iii. studies on serum of breast-fed and formula-fed neonates.the process of conjugation and secretion of bilirubin was studied in a group of healthy, full-term, exclusively breast-fed newborns and a control group of exclusively formula-fed infants by means of a reverse-phase high-performance liquid chromatographic analysis of bilirubins present in serum. the serum concentrations of unconjugated bilirubin, esterified bilirubin, and the proportion of diesterified bilirubin (as percent of esterified bilirubin) were not significantly different in breast- and ...19911797114
antitoxic properties of a preparation of glutathione s-transferase.pretreatment of rats with a preparation of the cationic form of rat liver cytosolic glutathione s-transferase 1-3 h before injection of a dose of n-nitroso-n-diethylamine equivalent to the ld50 of the drug completely protects the animals against the toxic effects of the drug. the mechanism of the protective action of glutathione s-transferase is discussed.19911797146
antitoxic properties of a preparation of glutathione s-transferase.pretreatment of rats with a preparation of the cationic form of rat liver cytosolic glutathione s-transferase 1-3 h before injection of a dose of n-nitroso-n-diethylamine equivalent to the ld50 of the drug completely protects the animals against the toxic effects of the drug. the mechanism of the protective action of glutathione s-transferase is discussed.19911797146
[patient's autonomy--it can be supported]. 20071797178
acute and chronic effects of parathion and 2,4 d on the oxygen consumption of chasmagnathus granulata (decapoda, brachyura).the effect of two pesticides widely used in argentina on the oxygen consumption of the estuarine crab chasmagnathus granulata was studied. constant pressure respirometers were employed to estimate the rate of oxygen consumption per weight unit of animals treated previously with each pesticide, both acute (96 h) and chronically (15 and 30 days). crabs exposed to parathion -an organophosphorate insecticide that causes the inhibition of acetylcholinesterase- show an increase of oxygen consumption a ...20061797200
acute and chronic effects of parathion and 2,4 d on the oxygen consumption of chasmagnathus granulata (decapoda, brachyura).the effect of two pesticides widely used in argentina on the oxygen consumption of the estuarine crab chasmagnathus granulata was studied. constant pressure respirometers were employed to estimate the rate of oxygen consumption per weight unit of animals treated previously with each pesticide, both acute (96 h) and chronically (15 and 30 days). crabs exposed to parathion -an organophosphorate insecticide that causes the inhibition of acetylcholinesterase- show an increase of oxygen consumption a ...20061797200
transcatheter management of pseudoaneurysms complicating pancreatitis.hemorrhage from rupture of an arterial pseudoaneurysm is a potentially fatal complication of pancreatitis. seventeen patients underwent transcatheter embolization of 23 arteries for the treatment of 20 arterial pseudoaneurysms secondary to pancreatitis. their records were reviewed retrospectively to evaluate the clinical benefit of transcatheter therapy. at presentation, 15 of the 17 patients had gastrointestinal, intrasplenic, retroperitoneal, intraperitoneal, or postoperative wound bleeding. t ...20061797219
transcatheter management of pseudoaneurysms complicating pancreatitis.hemorrhage from rupture of an arterial pseudoaneurysm is a potentially fatal complication of pancreatitis. seventeen patients underwent transcatheter embolization of 23 arteries for the treatment of 20 arterial pseudoaneurysms secondary to pancreatitis. their records were reviewed retrospectively to evaluate the clinical benefit of transcatheter therapy. at presentation, 15 of the 17 patients had gastrointestinal, intrasplenic, retroperitoneal, intraperitoneal, or postoperative wound bleeding. t ...20061797219
the sources of calcium for carbachol-induced contraction in the circular smooth muscle of guinea-pig stomach.1. the action of carbachol on the mechanical activity of circular muscle from guinea-pig upper stomach was studied. high concentrations of carbachol (e.g. 10(-4) m) produced a rapid phasic contraction followed by a smaller, sustained tonic contraction. low concentrations (e.g. 10(-7) m) caused a contraction which did not generally show marked distinction between phasic and tonic components. 2. the response to 10(-7) m carbachol was very sensitive to 10(-5) m nifedipine as was the phasic response ...19911797308
the sources of calcium for carbachol-induced contraction in the circular smooth muscle of guinea-pig stomach.1. the action of carbachol on the mechanical activity of circular muscle from guinea-pig upper stomach was studied. high concentrations of carbachol (e.g. 10(-4) m) produced a rapid phasic contraction followed by a smaller, sustained tonic contraction. low concentrations (e.g. 10(-7) m) caused a contraction which did not generally show marked distinction between phasic and tonic components. 2. the response to 10(-7) m carbachol was very sensitive to 10(-5) m nifedipine as was the phasic response ...19911797308
structural investigations of glucans from cultures of glomerella cingulata spaulding & von schrenck.methylation analysis, enzymic digestion, n.m.r. spectroscopy, and smith degradation showed that the major extracellular polysaccharide, isolated from cultures of the fungus glomerella cingulata, was a (1----3)-beta-d-glucan with side chains of 1-4 (1----3)-linked beta-d-glucose residues attached to position 6. a (1----6)-beta-d-glucan was produced by the fungus in small proportions. treatment of the (1----3,1----6)-beta-d-glucan (890,315) with greater than 0.05m naoh at greater than 150 degrees, ...19911797397
structural investigations of glucans from cultures of glomerella cingulata spaulding & von schrenck.methylation analysis, enzymic digestion, n.m.r. spectroscopy, and smith degradation showed that the major extracellular polysaccharide, isolated from cultures of the fungus glomerella cingulata, was a (1----3)-beta-d-glucan with side chains of 1-4 (1----3)-linked beta-d-glucose residues attached to position 6. a (1----6)-beta-d-glucan was produced by the fungus in small proportions. treatment of the (1----3,1----6)-beta-d-glucan (890,315) with greater than 0.05m naoh at greater than 150 degrees, ...19911797397
[heterotopic pregnancy. a case report and review of the literature].a case reported of simultaneous intrauterine and extrauterine pregnancy, is presented, accompanied by a spontaneous abortion, in the 8th week of gestation, and 3 weeks later, rupture of left tubal pregnancy. frequency and etiologic factors, as well as diagnostic possibilities are discussed.20071797620
role of faecal leucocytes in the diagnostic evaluation of acute diarrhoea.the value of faecal leucocyte examination was assessed in 400 infants with acute diarrhoea and 40 normal healthy infants. enteropathogens were isolated from 28.75%. escherichia coli was the commonest (16.5%) followed by salmonella typhimurium (7%), vibrio cholerae (3.25%) and shigella flexneri (1.5%). exudative response was observed in 57.1% of stools with salmonella and 66.6% each with shigella and e.i.e.c. infections. 81.3%, 89.5% and 87.7% of stools from which epec and etec and no enteropatho ...19911797652
aspects of the analytic relationship.in this article the analysand-analyst relationship is investigated from the classical and from the post-classical point of view. this leads to the distinction of four fundamental aspects of the analytic relationship: the realistic relationship, the working relationship, the transference relationship, and the primary relationship. similarities and differences between these various aspects of the analytic relationship are discussed. examples of confusion about the aspects are given. disagreement a ...20061797722
aspects of the analytic relationship.in this article the analysand-analyst relationship is investigated from the classical and from the post-classical point of view. this leads to the distinction of four fundamental aspects of the analytic relationship: the realistic relationship, the working relationship, the transference relationship, and the primary relationship. similarities and differences between these various aspects of the analytic relationship are discussed. examples of confusion about the aspects are given. disagreement a ...20061797722
serotype distribution and antimicrobial resistance of shigella isolates in singapore.serogrouping of 506 shigella strains isolated in singapore from 1986 to 1990 showed that shigella flexneri (60.3%) was the most common, followed by s. sonnei (33.6%), s. boydii (3.2%) and s. dysenteriae (3%). of the 23 shigella serotypes identified, the predominant ones were s. flexneri types 2a and 1b, s. boydii types 1 and 5, and s. dysenteriae types 1 and 3. more than 80% of the shigella species were resistant to at least one antimicrobial drug, and the incidence of multiresistance was partic ...19911800565
[a case of idiopathic aseptic osteonecrosis of the patellae: repeat study of tc-99m hmdp bone scintigraphy in a reparative phase].a 37-year-old woman entered our hospital because of bilateral knee pain. tc-99m hmdp bone scintigram demonstrated increased activity in the bilateral patellae and cold lesion in the center and left lateral segments of the left patellae, so-called doughnut pattern. trephine biopsy was performed to prove bilateral idiopathic asepct osteonecrosis of the patellae. the knee pain subsided and a bone scan 5 months later demonstrated increased activity in the bilateral patellae more widely than initial ...20061800777
[a case of idiopathic aseptic osteonecrosis of the patellae: repeat study of tc-99m hmdp bone scintigraphy in a reparative phase].a 37-year-old woman entered our hospital because of bilateral knee pain. tc-99m hmdp bone scintigram demonstrated increased activity in the bilateral patellae and cold lesion in the center and left lateral segments of the left patellae, so-called doughnut pattern. trephine biopsy was performed to prove bilateral idiopathic asepct osteonecrosis of the patellae. the knee pain subsided and a bone scan 5 months later demonstrated increased activity in the bilateral patellae more widely than initial ...20061800777
coincident recording and stimulation of single and multiple neuronal activity with one extracellular microelectrode.this paper describes how an extracellular microelectrode may be used to stimulate neurons with brief, rectangular pulses and afterwards directly record the resultant activity. two obstacles are the stimulus artifact lingering in the electrical circuitry and transient tip potentials (ttps) arising from ion depletion at the electrode-tissue interface. electronic switching between the stimulus source and the recording amplifier eliminates direct stimulus artifact from the electrical circuitry, alth ...19911800855
a fatal case associated with shigellosis and vibrio fluvialis bacteremia. 19911802539
the immunobiology of mycoplasma arthritidis and its superantigen mam. 19911802617
the immunobiology of mycoplasma arthritidis and its superantigen mam. 19911802617
transient activation of 1-o-alkyl-sn-glycero-3-phosphocholine: acetyl-coa acetyltransferase during the incubation of macrophages.the activity of the platelet-activating factor (paf)-synthesizing enzyme, 1-o-alkyl-sn-glycero-3-phosphocholine (lysopaf):acetyl-coa acetyltransferase (ec 2.3.1.67) in alveolar macrophage lysate was found to be elevated after warming the cells to 37 degrees c. such an increase in enzyme activity was detectable only when intact cells were warmed. the stimulation was transient, reaching a peak at 2 min, and then gradually decreased to the control level. we could not find increased paf formation in ...19911805090
technological aspect of the production of live dysentery vaccines for oral administration.an experimental technology for the production of live freeze-dried vaccines prepared from attenuated shigella flexneri 2a and shigella sonnei i strains was developed. it is based on the cultivation of bacterial strains in a fermentor under conditions which ensure high yields. the strains grow in s-form, their antigenic structure is preserved and they remain non-virulent. the attenuating markers are stable. the freeze-dried vaccines retain good immunogenicity when applied intra-intestinally to ra ...19911805499
changing antibiotic sensitivity patterns in shigellosis.over five and a half months stool cultures were performed in 154 patients admitted with suspected bacillary dysentery to the professorial paediatric unit of the teaching hospital, galle. thirty one patients had a positive stool culture; shigella dysenteriae type 1 was isolated in 23 patients, and s flexneri in 8. in both groups the antibiotic sensitivity pattern was uniform, the only difference being s dysenteriae type 1 being resistant to nalidixic acid while s flexneri was sensitive. this anti ...19911807844
neonatal shigellosis. 19911808054
milk secretory iga related to shigella virulence antigens.20 mexico city and 23 houston, texas colostrum samples, and 21 mexican and 25 houston mature milk samples were analyzed by elisa and western blot, respectively, for antibodies against the virulence plasmid of shigella flexneri serotype 5 strain m9ot. the method involved comparing water extracts of milk in elisa and western blot determinations of antigens against shigella flexneri strain m9ot which is fully virulent, to those against m9ot a2 which lacks the virulence plasmid. while there are at ...19911809012
study of high density escherichia coli fermentation for production of porcine somatotropin protein.recombinant e. coli strains and culture conditions were studied for the fermentation expression of porcine somatotropin (pst) inclusion bodies under the control of a pl promoter. our objective was to achieve high cell density together with a high level of recombinant protein expression. improved fermentation conditions included oxygen enrichment, yeast extract (ye) effect, optimal specific growth to switch on gene expression, and feeding strategies. to maintain a low residual glucose concentrati ...19911809195
[anterior choroidal artery syndromes].three cases of anterior choroidal artery territorial infarction, diagnosed by computerized tomography, with the triad of hemiplegia, hemianaesthesia and hemianopia, pure motor stroke and ataxic hemiparesis are described. major and minor (lacular) infarctions in the territory of the anterior choroidal artery involve almost exclusively the basal segment of the posterior limb of the internal capsule and manifest themselves by symptoms of long pathway lesion. based on the published case reports and ...20051809518
results of meniscal repair and partial meniscectomy in stable knees.in a study using matched pairs of 50 patients, meniscal repair was compared with partial meniscectomy in knees without major ligament injuries. there was a failure rate of 24% after meniscal repair in a follow up from 6 to 9 years after operation. a further meniscectomy was needed in 16% of those who had had a partial meniscectomy. function was better after meniscal repair, but the compliance rate was lower because of the prolonged rehabilitation. repair led to less osteoarthritis than menisecto ...20061809716
[the role of a secondary immunodeficiency in the pathogenesis of different forms of dysentery]. 19911810052
[the treatment of protracted forms of flexner dysentery].the clinical efficacy of sodium nucleinate (sn) combined with splenin and quercetin given for lingering flexner's dysentery in a group of 43 patients was compared with that of routine therapy used in a group of the same number of patients. it has been established that the above drug combination favours the elimination of the pathological symptoms of dyspepsia, the arrest of bacterial isolation and normalization of the immune status. provided the effect of the combined drug treatment is insuffici ...19911810053
[humoral and cellular immunity in patients with acute dysentery]. 19911810054
[the functional status of the endocrine pancreas in patients with acute intestinal infections].ria was used to measure the content of insulin, c-peptide and glucagon in blood plasma of 84 patients with acute dysentery and food toxicoinfections. the studies were carried out in the acute disease period and before the discharge from hospital. the data obtained indicate that despite the appreciable differences in the disease pathogenesis, the pathophysiological mechanisms influencing pancreatic function are similar in many respects. the changes are characterized by an increase in plasma insul ...19911810055
serotonin immunoreactivity in the intermediate lobe of the rat pituitary.immunocytochemical staining for serotonin (5-ht) in paraffin-embedded sections of rat pituitary resulted in the localization of reactive nerve fibres and cell bodies in the intermediate lobe. immunostaining was also found in the anterior and posterior lobes. labelled nerve fibres appear to enter the intermediate lobe from the neural lobe through the interlobular spaces. these fibres are relatively scarce and lightly stained. neuroglandular contacts were identified between varicose nerve endings ...19911810536
[antigenic analysis and identification of serotype for an arguable strain of shigella].a strain of shigella, 51331, was isolated abroad in 1935, and stored in the center for medical culture collection, beijing. since the serotype of this strain was arguable in china. it was identified as sh. flexneri var. x with antigenic analysis. as agglutinin absorption technic was used in preparing diagnostic factor serum, it appears that the culture of strain 51331 could be agglutinated by shigella antiserum flexner type 3 (sh. flexneri) made in china and england. the present author suggested ...19911814048
supero-inferior ventricles with normal atrioventricular and ventriculoarterial connections. 20061821002
supero-inferior ventricles with normal atrioventricular and ventriculoarterial connections. 20061821002
synthesis and siderophore activity of albomycin-like peptides derived from n5-acetyl-n5-hydroxy-l-ornithine.n5-acetyl-n5-hydroxy-l-ornithine (1), the key constituent of several microbial siderophores, has been synthesized in 23% yield overall from n-cbz-l-glutamic acid 1-tert-butyl ester (6) derived from l-glutamic acid. reduction of 6 to 7 and treatment with n-[(trichloroethoxy)carbonyl]-o-benzylhydroxylamine (8), and diethyl azodicarboxylate and triphenylphosphine followed by deprotection produced the protected n5-acetyl-n5-hydroxy-l-ornithine derivatives 11 and 12 in large quantities (10-20 g). fol ...19911825849
synthesis and siderophore and antibacterial activity of n5-acetyl-n5-hydroxy-l-ornithine-derived siderophore-beta-lactam conjugates: iron-transport-mediated drug delivery.n5-acetyl-n5-hydroxy-l-ornithyl-n5-acetyl-n5-hydroxy-l-ornithyl-n5-acety l- n5-hydroxy-l-ornithine, the functionally instrumental component of the albomycins and ferrichromes, has been incorporated as a "carrier" substructure into both carbacephalosporin and oxamazin type beta-lactam antibiotics. the previously synthesized protected version of this tripeptide (14) was coupled with various beta-lactam analogues 17, 19, 24, and 25 to give protected conjugates 21, 22, 26, and 27. final deprotection ...19911825850
the lumbar disc: evaluating the causes of pain. 20061828114
the e2f transcription factor is a cellular target for the rb protein.although it is generally believed that the product of the retinoblastoma susceptibility gene (rb1) is an important regulator of cell proliferation, the biochemical mechanism for its action is unclear. we now show that the rb protein is found in a complex with the e2f transcription factor and that only the under phosphorylated form of rb is in the e2f complex. moreover, the adenovirus e1a protein can dissociate the e2f-rb complex, dependent on e1a sequence also critical for e1a to bind to rb. the ...20061828392
the e2f transcription factor is a cellular target for the rb protein.although it is generally believed that the product of the retinoblastoma susceptibility gene (rb1) is an important regulator of cell proliferation, the biochemical mechanism for its action is unclear. we now show that the rb protein is found in a complex with the e2f transcription factor and that only the under phosphorylated form of rb is in the e2f complex. moreover, the adenovirus e1a protein can dissociate the e2f-rb complex, dependent on e1a sequence also critical for e1a to bind to rb. the ...20061828392
this is mary. 20061828484
this is mary. 20061828484
[acute febrile polyarthritis disclosing horton's disease]. 20061828585
[acute febrile polyarthritis disclosing horton's disease]. 20061828585
suppression of vascular injury at the arthus reaction site by a complement inhibitor, 5,5',5''-(1,3,6-naphthalene-triyl-tris[sulfonylimino])-tris (1,3-benzene disulfonic acid) hexasodium salt.a novel polyanionic complement inhibitor 5,5,5''-(1,3,6-naphthalene-triyl-tris[sulfonylimino])-tris(1 ,3-benzene- disulfonic acid) hexasodium salt (compound iib) was tested for its ability to suppress vascular injury at the site of the arthus reaction (ar). in control animals in which ar was evoked without drug treatment, venules at ar sites ranged from normal (arbitrarily defined as stage i) to destroyed (stage v). between these two ends of the spectrum were venules with an accumulation of cell ...19911828755
aggressive chemotherapy for acute leukaemia frequently causes intestinal protein leakage.cytostatic drugs are known to produce disturbances in intestinal absorption of carbohydrates. to further explore the gastrointestinal (gi) toxicity of cytostatic therapy, 37 patients with acute leukemia were investigated during and/or after remission induction courses by the use of the differential sugar absorption test (dsat) and the intestinal clearance of alpha-1-antitrypsin (claat). the ratio of the lactulose to the mannitol excretion in the urine was found abnormal in 44% of the tests. the ...20061828960
aggressive chemotherapy for acute leukaemia frequently causes intestinal protein leakage.cytostatic drugs are known to produce disturbances in intestinal absorption of carbohydrates. to further explore the gastrointestinal (gi) toxicity of cytostatic therapy, 37 patients with acute leukemia were investigated during and/or after remission induction courses by the use of the differential sugar absorption test (dsat) and the intestinal clearance of alpha-1-antitrypsin (claat). the ratio of the lactulose to the mannitol excretion in the urine was found abnormal in 44% of the tests. the ...20061828960
localization of interleukin-1 receptor antagonist mrna in rat brain.interleukin-1 (il-1) is an inflammatory peptide hormone, with potent neuroendocrine effects. il-1 stimulates the central nervous system production of corticotropin-releasing hormone (crh), growth hormone (gh), thyroid-stimulating hormone (tsh), and somatostatin, and inhibits the secretion of prolactin and luteinizing hormone (lh). interleukin-1 receptor antagonist (il-1ra) is a novel cytokine, recently purified, characterized, and cloned. il-1ra is a pure endogenous antagonist of il-1:il-1 funct ...19911829036
localization of interleukin-1 receptor antagonist mrna in rat brain.interleukin-1 (il-1) is an inflammatory peptide hormone, with potent neuroendocrine effects. il-1 stimulates the central nervous system production of corticotropin-releasing hormone (crh), growth hormone (gh), thyroid-stimulating hormone (tsh), and somatostatin, and inhibits the secretion of prolactin and luteinizing hormone (lh). interleukin-1 receptor antagonist (il-1ra) is a novel cytokine, recently purified, characterized, and cloned. il-1ra is a pure endogenous antagonist of il-1:il-1 funct ...19911829036
percutaneous transjugular portosystemic shunt.--to determine the effectiveness of the palmaz balloon expandable stent for the creation of a transjugular intrahepatic portosystemic shunt. the device is designed to achieve portal decompression in patients with variceal hemorrhage secondary to portal hypertension.20071829120
[the manifestations of the epidemic process in shigellosis and their theoretical interpretation].this work, based on the retrospective analysis of shigellosis morbidity among organized groups of adults, as well as the whole population of the city, demonstrates the manifestations of the epidemic process. water supply was common in the city, while water consumption was autonomous. the organized groups of adults did not use the products of the local milk-processing factory. the following facts were established. the dynamics of morbidity in flexner's dysentery showed the change of dominating va ...19911830443
[the structure of the population morbidity with specific intestinal infections in areas with different intensities in the development of the epidemic process and an evaluation of its manifestations].the authors analyze the morbidity structure in five enteric infections (typhoid fever, dysentery caused by shigella flexneri and shigella sonnei, hepatitis a, and hepatitis e (non a, non b) with the fecal/oral mechanism of the agent transmission) in three towns of turkmenia and in the town of novomoskovsk, tula province. the incidence of s. sonnei dysentery was found higher in novomoskovsk and that of the rest enteric infections under study in turkmenia. the incidence of typhoid fever and hepati ...19911836925
comparison of within-group variabilities across older and younger adults: a meta-analysis.the hypothesis that individual differences in performance scores increase with increasing adult age was reviewed. a meta-analysis of memory articles appearing in the journal of gerontology from 1985 to 1990 was conducted to examine potential age differences in within-group variabilities. there was no strong evidence in the data reported here that overall younger adults are consistently more alike in their memory abilities than are older adults. this result was obtained whether the younger group ...20071838980
[hemodynamic and respiratory changes during laparoscopic cholecystectomy carried out under epidural anesthesia]. 20071839167
ascaris in the common bile duct: diagnosis by ultrasound and endoscopic retrograde cholangiopancreatography (ercp) and extraction by balloon catheter.this is a case report of ascaris worm in the common bile duct in a 61 year old lady. ultrasound diagnosis was initially made based on the presence of linear hyperreflective foci within the common bile duct. ercp confirmed a single worm within the duct. balloon extraction was then successfully carried out following papillotomy. this case illustrates the value of ultrasound in the definitive diagnosis of biliary ascariasis and the therapeutic role of ercp.19911839928
ascaris in the common bile duct: diagnosis by ultrasound and endoscopic retrograde cholangiopancreatography (ercp) and extraction by balloon catheter.this is a case report of ascaris worm in the common bile duct in a 61 year old lady. ultrasound diagnosis was initially made based on the presence of linear hyperreflective foci within the common bile duct. ercp confirmed a single worm within the duct. balloon extraction was then successfully carried out following papillotomy. this case illustrates the value of ultrasound in the definitive diagnosis of biliary ascariasis and the therapeutic role of ercp.19911839928
genetic analysis of the enterobactin gene cluster in shigella flexneri.the genes for transport and synthesis of the phenolate siderophore enterobactin are present on the chromosomes of both ent+ and ent- clinical isolates of shigella flexneri. to determine why ent- s. flexneri isolates fail to express a functional enterobactin system, the structure and expression of enterobactin genes were examined. several alterations may be responsible for the inability of s. flexneri to express enterobactin. (i) the mrna levels produced from the entc and fepb genes were not dere ...19911846151
molecular epidemiology of shigella infections: plasmid profiles, serotype correlation, and restriction endonuclease analysis.plasmid isolation was used to refine the epidemiologic analysis for 168 shigellosis cases in pima county, ariz. plasmids of less than 20 kb were used for comparison of plasmid profiles. plasmid patterns for each species were distinct. a total of 57 of 74 (77%) shigella flexneri strains could be placed into seven plasmid patterns, 70 of 79 (89%) shigella sonnei strains could be placed into seven patterns, 12 shigella boydii strains could be placed into six patterns, and each of 3 shigella dysente ...19911847148
interstitial chromosomal deletion within 4q11-q13 in a human hepatoma cell line.southern blot analysis revealed the presence of an aberrant albumin gene as well as a normal one in a human hepatoma cell line, huh-7. a genomic sequence carrying this altered gene was isolated and characterized. this clone contains a 3-kbp 3' segment of the albumin gene linked to a non-albumin sequence at intron 11. the non-albumin sequence is assigned to chromosome 4q12-q13 by in situ hybridization. this indicates an interstitial deletion of a chromosomal segment within 4q11-q13 because the al ...19911847664
kinetic analysis of transport and opioid receptor binding of [3h](-)-cyclofoxy in rat brain in vivo: implications for human studies.[3h]cyclofoxy (cf: 17-cyclopropylmethyl-3,14-dihydroxy-4,5-alpha-epoxy-6-beta-fluoromorp hinan) is an opioid antagonist with affinity to both mu and kappa subtypes that was synthesized for quantitative evaluation of opioid receptor binding in vivo. two sets of experiments in rats were analyzed. the first involved determining the metabolite-corrected blood concentration and tissue distribution of cf in brain 1 to 60 min after i.v. bolus injection. the second involved measuring brain washout for 1 ...19911847702
virulence-associated chromosomal loci of shigella flexneri identified by random tn5 insertion mutagenesis.shigellae are the causative agents of bacillary dysentery and are capable of invading epithelial cells, multiplying therein and spreading into adjacent cells. to identify genes on the chromosome associated with the virulence phenotype, 9114 independent tn5 insertion mutants were isolated in a virulent strain of shigella flexneri. by using an in vitro assay for intercellular spread or an animal infection model, the serény test, 50 chromosomal tn5 mutants with reduced virulence were identified. th ...19911849606
evidence that the asparagine 322 mutant of the lactose permease transports protons and lactose with a normal stoichiometry and accumulates lactose against a concentration gradient.the single asparagine 322 mutant of the lactose permease was made by constructing a hybrid plasmid which contained the amino-terminal coding sequence from the wild-type permease gene and the carboxyl-terminal coding sequence from a previously characterized double mutant permease which contained an asparagine residue at position 322. since histidine at position 322 has been postulated to be critically involved with h+ transport and the active accumulation of sugars, the ability of the asn-322 mut ...19911849889
structure and function of the maize spm transposable element.the spm's primary transcript is alternatively spliced to give at least 4 different transcripts which code for proteins with extensive overlapping domains. two of these proteins, the tnpa and tnpd gene products, are necessary and sufficient to promote dspm transposition in tobacco. moreover, the tnpa gene product is also sufficient to suppress the basal level of expression observed in some dspm-disrupted genes, and probably to activate the expression of inactive elements and of other dspm-disrupt ...19911851643
miniature manipulator with microelectrode for chronic recording of single units from freely-moving animals.we report a simple recording and stimulating system, a miniature manipulator with a microelectrode (mmm) that can be mounted on animal's skull. the system consists of a miniature manipulator and a microelectrode which are used in one body. several mmms can be implanted simultaneously into the brain as the part of the manipulator is small. with this device, recording of single units from several different cortices is possible from awake and unrestricted animals.19911851979
regulation of alcohol consumption by the renin-angiotensin system: a review of recent findings and a possible mechanism of action.the renin-angiotensin system has traditionally been associated with the regulation of fluid and electrolyte balance. in this review we summarize the data which ascribes a completely new function to this system, i.e., the regulation of alcohol consumption. in addition, we suggest a possible mechanism for this effect based on the concept of a satiety or stop process. the approach taken was to examine the effect on alcohol intake of a wide variety of drug, genetic, dietary, surgical and neurosurgic ...20071852316
olfactory dysfunction in parkinson's disease.an olfactory function test in 18 patients with parkinson's disease (pd) and 10 age-matched control subjects was performed. both detection and recognition thresholds were measured with five kinds of synthesized odorants (t & t olfactometry). before each test, rhinoscopic inspections were performed to exclude subjects who could have respiratory hyposmia. both detection and recognition thresholds in patients with pd were significantly elevated in comparison with those of control subjects. auditory ...20071852411
autokinetic illusion as affected by suggestions of experimenter and observer.two experiments were done to examine whether an experimenter's suggestion and self-suggestion could affect the autokinetic illusion and to specify that effect. exp. i compared the effect of a facilitative suggestion with a suppressive one, by measuring the moving latency, duration, frequency, and by analyzing the movement trace. time and frequency did not detect any effects of marked individual differences. trace analysis, on the other hand, showed that suggestions were effective in the expected ...20071852560
alternating-pattern z-plasties in association with v-y advancements: a new idea of multiple z-plasties.a new principle of arrangement in multiple z-plasties is advocated. by placing z's in an alternating pattern in combination with v-y plasties, more effective and harmless elongation of skin will be possible.20071852835
[community epidemiology]. 20071853100
photoaffinity labeling of rat type i iodothyronine deiodinase.the photoreactive compound p-nitrophenyl-2-diazo-3,3,3-trifluoropropionate (pal) was coupled to [125i]rt3, t4, or t3 and incubated with liver and kidney microsomes of hypo-, hyper-, or euthyroid rats to identify the type i iodothyronine deiodinase. various substrates or inhibitors of the enzyme, including rt3, t4, t3, 6-n-propylthiouracil (ptu), and iopanoic acid, were used as competitors to establish the specificity of protein labeling. the pal derivatization enhanced the behavior of t4 and t3 ...19911855452
body mass index variations: centiles from birth to 87 years.this report provides body mass index (weight/height2) values for the french population from birth to the age of 87 years. bmi curves increase during the first year, decrease until the age of 6, increase again up to 65 years and decrease thereafter. these variations reflect the total changes of fat body mass during life. the 50th centile values of wt/ht2 at the ages of 20, 40, 60, 80 years are 21.5, 24.6, 25.4, 24.4 kg/m2 for men and 20.6, 22.6, 24.1, 23.4 kg/m2 for women. the values for the 3rd, ...20071855495
Displaying items 2501 - 2600 of 11070