Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| another look at baseball player initials and longevity. | abel and kruger (2007) reported that major league baseball players whose names have positive initials (such as ace or god) live an average of 13 years longer than do players with negative initials (such as ass or bad) or players with neutral initials (such as ghr or tsw). however, this conclusion is based on a very small sample, selective initials, and a flawed statistical test. there is no statistically significant relationship between initials and longevity for major league baseball players wh ... | 2011 | 21466094 |
| [positive impact of ass on cancer incidence and mortality]. | 2011 | 21476184 | |
| inhibition of staphylococcus aureus cysteine proteases by human serpin potentially limits staphylococcal virulence. | bacterial proteases are considered virulence factors and it is presumed that by abrogating their activity, host endogenous protease inhibitors play a role in host defense against invading pathogens. here we present data showing that staphylococcus aureus cysteine proteases (staphopains) are efficiently inhibited by squamous cell carcinoma antigen 1 (scca1), an epithelial-derived serpin. the high association rate constant (k(ass)) for inhibitory complex formation (1.9×10(4) m/s and 5.8×10(4) m/s ... | 2011 | 21476872 |
| octave spanning supercontinuum in an as₂s₃ taper using ultralow pump pulse energy. | an octave spanning spectrum is generated in an as₂s₃ taper via 77 pj pulses from an ultrafast fiber laser. using a previously developed tapering method, we construct a 1.3 μm taper that has a zero-dispersion wavelength around 1.4 μm. the low two-photon absorption of sulfide-based chalcogenide fiber allows for higher input powers than previous efforts in selenium-based chalcogenide tapered fibers. this higher power handling capability combined with input pulse chirp compensation allows an octave ... | 2011 | 21479003 |
| inhibition of lps toxicity by hepatic argininosuccinate synthase (ass): novel roles for ass in innate immune responses to bacterial infection. | lipopolysaccharide (lps), a structural component of gram-negative bacteria, is implicated in the pathogenesis of endotoxemia/sepsis and multi-organ injury, including liver damage. we have shown that argininosuccinate synthase (ass), a hepatic enzyme of the urea cycle, accumulates in circulation within 1h after treatment with both lps alone and hepatotoxic combination of lps and d-galactosamine. these findings indicate ass as a sensitive biomarker of liver responses to bacterial endotoxin. furthe ... | 2011 | 21481813 |
| death secondary to a donkey's bites. | we present a unique case of death due to the assault and bites of a donkey on a 65-year-old man. the farmer, found dead in his farmyard, had a very deep wound in the anterior region of the neck, with a sharp transection of the trachea and severe bleeding by several minor vessels wall disruptions. the cause of death was established to be massive bleeding combined with asphyxia due to aspiration of the blood. moreover, multiple contusions with associated skin abrasions and perforations were presen ... | 2011 | 21490498 |
| the medicinal use of realgar (as(4)s(4)) and its recent development as an anticancer agent. | arsenicals have been known as poisons and paradoxically as therapeutic agents. in the early 1970s, chinese physicians from harbin revived the medicinal use of arsenicals as anticancer agents. notable success was observed in the treatment of acute promyelocytic leukemia (apl) with arsenic trioxide (ato). the fda approved ato injection in the year 2000 for the treatment of apl. in contrast, the clinical use of the other arsenical, realgar (as(4)s(4)), is currently much less established, though it ... | 2011 | 21497649 |
| detection of antisynthetase syndrome in patients with idiopathic interstitial pneumonias. | objectives: antisynthetase syndrome (ass) is characterized by autoantibodies to aminoacyl-trna synthetases (anti-synthetase) and it is frequently associated with interstitial lung disease. the purpose of this study was to elucidate the prevalence and characteristics of the anti-synthetase positive subpopulation among idiopathic interstitial pneumonias (iips) and to clarify the importance of screening for these antibodies. methods: a retrospective study was performed in 198 consecutive cases with ... | 2011 | 21514811 |
| cognitively preserved subjects with transitional cerebrospinal fluid ß-amyloid 1-42 values have thicker cortex in alzheimer's disease vulnerable areas. | background: establishing the relationship between cerebrospinal fluid (csf) ß-amyloid 1-42 (aß) and cortical thickness (cth) would represent a major step forward in the understanding of the alzheimer's disease (ad) process. we studied this relationship in a group of healthy control subjects and subjects with subjective memory complaints with preserved cognitive function at neuropsychological testing. methods: in this cross-sectional study, 33 individuals (17 healthy control subjects and 16 subje ... | 2011 | 21514924 |
| genetic diversity of the class ii major histocompatibility dra locus in european, asiatic and african domestic donkeys. | the major histocompatibility complex (mhc) genes coding for antigen presenting molecules are the most polymorphic genes in vertebrate genome. the mhc class ii dra gene shows only small variation in many mammalian species, but it exhibits relatively high level of polymorphism in equidae, especially in donkeys. this extraordinary degree of polymorphism together with signatures of selection in specific amino acids sites makes the donkey dra gene a suitable model for population diversity studies. th ... | 2011 | 21515411 |
| monitoring of genetic diversity in the endangered martina franca donkey population. | the martina franca (mf) donkey, an ancient native breed of apulia, was mostly famous for mule production. the breed was at serious risk of extinction in the 1980s following the decrease in demand for draft animals because they were increasingly replaced by agricultural machinery. much has been done in the last few decades to safeguard the existing donkey breeds, but the situation remains critical. successful implementation of conservation measures includes an evaluation of the present degree of ... | 2011 | 21521813 |
| association of plasma aß peptides with blood pressure in the elderly. | aß peptides are often considered as catabolic by-products of the amyloid ß protein precursor (app), with unknown physiological functions. however, several biological properties have been tentatively attributed to these peptides, including a role in vasomotion. we assess whether plasma aß peptide levels might be associated with systolic and diastolic blood pressure values (sbp and dbp, respectively). | 2011 | 21525986 |
| glutamate receptors in preclinical research on alzheimer's disease: update on recent advances. | the cognitive and related symptoms of alzheimer's disease are mainly attributable to synaptic failure. here we review recent research on how the alzheimer's disease amyloid ß-protein (aß) affects glutamate receptors and fast excitatory synaptic transmission and plasticity of that transmission. l-glutamate, the main excitatory neurotransmitter in the brain, has long been implicated in causing nmda receptor-mediated excitotoxicity leading to neurodegeneration in the late stages of the disease. how ... | 2011 | 21536064 |
| synergy of the antiretroviral protease inhibitor indinavir and chloroquine against malaria parasites in vitro and in vivo. | many malaria-endemic areas are also associated with high rates of human immunodeficiency virus (hiv) infection. an understanding of the chemotherapeutic interactions that occur during malaria and hiv co-infections is important. our previous studies have demonstrated that some antiretroviral protease inhibitors are effective in inhibiting plasmodium falciparum growth in vitro. currently, studies examining the interactions between antiretroviral protease inhibitors and antimalarial drugs are being ... | 2011 | 21537980 |
| c-terminal truncation of the transmembrane protein of an attenuated lentiviral vaccine alters its in vitro but not in vivo replication and weakens its potential pathogenicity. | preliminary studies revealed that the gene of the gp45 transmembrane protein (tm) of the attenuated equine infectious anemia virus (eiav) vaccine strain eiav(fddv13) had a high frequency of a premature stop codon at position 261w, which generated a 154-residue truncation at the c-terminus. eiav(fddv-tm36), a recombinant virus with the tm truncated at the intracytoplasmic (ct) domain due to the presence of a stop codon, was constructed based on eiav(fddv)3-8, which is a proviral derivative of the ... | 2011 | 21539871 |
| crystalline cr<sup>2+</sup>:znse/chalcogenide glass composites as active mid-ir materials. | we propose new transition metal (tm)-doped znse/as<sub>2</sub>s<sub>3</sub>:as<sub>2</sub>se<sub>3</sub> composite materials for mid-ir fiber lasers. the composites are the suspension of crystalline micro- and nanosized tm<sup>2+</sup>:znse or tm<sup>2+</sup>:zns powders in chalcogenide glasses with the refraction index matching. mid-ir room-temperature lasing of cr<sup>2+</sup>:znse/as<sub>2</sub>s<sub>3</sub>:as<sub>2</sub>se<sub>3</sub> microcomposite material is demonstrated at the 2.4 μm wa ... | 2011 | 21540917 |
| affiliative and aggressive behavior in a group of female somali wild ass (equus africanus somalicus). | we observed a group of three young female somali wild asses to develop an ethogram of social behavior in the first phase of a longer term study of social, sexual, and maternal/infant behavior. the most unexpected finding was the frequency and extent of aggressive interactions, which included charge, drive, neck wrestle, head butt, and body slam, behaviors previously reported only for males of other equid species. the overall frequency of aggressive behavior was higher than that of affiliative be ... | 2011 | 21541987 |
| expression and function of arginine-producing and consuming-enzymes in the kidney. | the kidney plays a key role in arginine metabolism. arginine production is controlled by argininosuccinate synthetase (ass) and argininosuccinate lyase (asl) which metabolize citrulline and aspartate to arginine and fumarate whereas arginine consumption is dependent on arginine:glycine amidinotransferase (gat), which mediates creatine and ornithine synthesis. histological and biochemical techniques have been used to study the distribution and activity of these enzymes in anatomically dissected s ... | 2011 | 21567240 |
| prevalence of strongyles and efficacy of fenbendazole and ivermectin in working horses in el sauce, nicaragua. | horses, mules and donkeys are indispensable farming and working animals in many developing countries, and their health status is important to the farmers. strongyle parasites are ubiquitous in grazing horses world-wide and are known to constitute a threat to equine health. this study determined the prevalence of strongyle infection, the efficacy of ivermectin and fenbendazole treatment, and strongyle re-infection rates of working horses during the dry months in nicaragua. one hundred and five ho ... | 2011 | 21570188 |
| pulmonary angiocentric lymphoma (lymphomatoid granulomatosis) in a donkey. | a 36-year-old donkey developed dyspnoea, pyrexia, hypoalbuminaemia and oedema. following continued clinical deterioration the donkey was humanely destroyed. grossly, there were numerous nodules (5-10mm) scattered throughout the lung. microscopically, the lung was infiltrated by an angiocentric and bronchocentric to diffuse mixed population of small mature and atypical lymphocytes, histiocytes, plasma cells and fewer eosinophils. the infiltrate was composed of numerous small mature and fewer atyp ... | 2011 | 21571299 |
| tris[4-(methyl-sulfan-yl)phen-yl]arsine. | in the title compound, c(21)h(21)ass(3), the three benzene rings make dihedral angles of 88.41 (10), 87.75 (9) and 74.74 (10)° with each other. the methyl-sulfanyl groups are roughly coplanar with their attached benzene rings [c-s-c-c torsion angles = -7.6 (2), 11.2 (2) and 4.1 (2)°]. in the crystal, weak c-h⋯π inter-actions link the mol-ecules. | 2010 | 21588406 |
| undeca-carbonyl-1κc,2κc,3κc-{tris-[4-(methyl-sulfanyl)-phen-yl]arsine-1κas}-triangulo-triruthenium(0). | the crystal structure of the title triangulo-triruthenium compound, [ru(3)(c(21)h(21)ass(3))(co)(11)], confirms that during the synthesis one equatorial carbonyl ligand is substituted by a monodentate arsine ligand, leaving one equatorial and two axial carbonyl substituents on an ru atom. the other two ru atoms each carry two equatorial and two axial carbonyl ligands. the three arsine-substituted benzene rings make dihedral angles of 77.94 (13), 86.37 (13) and 73.22 (12)° with each other. two of ... | 2010 | 21588476 |
| bis([μ-bis-(diphenyl-phosphino)methane-1:2κp:p']nona-carbonyl-1κc,2κc,3κc-{tris-[4-(methyl-sulfan-yl)phen-yl]arsine-3κas}-triangulo-triruthenium(0)) dichloro-methane monosolvate. | the asymmetric unit of the title triangulo-triruthenium compound, 2[ru(3)(c(21)h(21)ass(3))(c(25)h(22)p(2))(co)(9)]·ch(2)cl(2), consists of one triangulo-triruthenium complex mol-ecule and one half of a dichloro-methane mol-ecule which lies across a crystallographic inversion center, leading to the disorder of this mol-ecule over two positions of equal occupancy. the bis-(diphenyl-phosphino)methane ligand bridges an ru-ru bond and the monodentate arsine ligand bonds to the third ru atom. both th ... | 2010 | 21588546 |
| bis([μ-bis-(diphenyl-arsino)methane-1:2κas:as']nona-carbonyl-1κc,2κc,3κc-{tris-[4-(methyl-sulfan-yl)phen-yl]arsine-3κas}-triangulo-triruthenium(0)) dichloro-methane monosolvate. | the asymmetric unit of the title triangulo-triruthenium compound, 2[ru(3)(c(25)h(22)as(2))(c(21)h(21)ass(3))(co)(9)]·ch(2)cl(2), consists of one triangulo-triruthenium complex mol-ecule and one half of a dichloro-methane mol-ecule which lies across a crystallographic inversion center, leading to the disorder of this mol-ecule over two positions of equal occupancy. the bis-(diphenyl-arsino)methane ligand bridges an ru-ru bond and the monodentate arsine ligand bonds to the third ru atom. all arsin ... | 2010 | 21588547 |
| seminal parameters and field fertility of cryopreserved donkey jack semen after insemination of horse mares. | as mule production is often concentrated in remote areas of the world, a simplified semen cryopreservation protocol is required. | 2011 | 21592212 |
| comparative study on 15-ketodihydro-pgf(2α) plasma concentrations in newborn horses, donkeys and calves. | the aim of this study was to compare the plasma profiles of 15-ketodihydro-pgf(2α) (pgm) in healthy neonates of three different species from birth until the third week of life. twenty-four horse foals, 12 donkey foals, and 9 calves were studied. blood samples were collected at 10, 20 and 30 min after birth, at 3, 24 and 72 h after birth, and at 7, 10, 17 and 21 days of life. all mothers experienced normal gestation lengths and normal, spontaneous deliveries. all newborns were judged mature and v ... | 2011 | 21599765 |
| in vitro maturation and artificial activation of donkey oocytes. | three media were evaluated for their ability to support in vitro maturation of donkey (equus asinus) oocytes and their development after parthenogenetic activation. the basal medium for medium 1 (m1) and medium 2 (m2) was m199 and dmem/f12 respectively, whereas, medium 3 (m3) consisted of equal parts (v/v) of m199 and dmem/f12. all three media were supplemented with 10% (v/v) fetal calf serum, 0.01 units/ml porcine fsh, 0.01 units/ml equine lh, 200 ng/ml insulin-like growth factor 1(igf-i), 10 μ ... | 2011 | 21601263 |
| ammonia control in children with urea cycle disorders (ucds); phase 2 comparison of sodium phenylbutyrate and glycerol phenylbutyrate. | twenty four hour ammonia profiles and correlates of drug effect were examined in a phase 2 comparison of sodium phenylbutyrate (napba) and glycerol phenylbutyrate (gpb or hpn-100), an investigational drug being developed for urea cycle disorders (ucds). study design: protocol hpn-100-005 involved open label fixed-sequence switch-over from the prescribed napba dose to a pba-equimolar gpb dose with controlled diet. after 7days on napba or gpb, subjects underwent 24-hour blood sampling for ammonia ... | 2011 | 21612962 |
| combined lysosomal protein transmembrane 4 beta-35 and argininosuccinate synthetase expression predicts clinical outcome in hepatocellular carcinoma patients. | the newly-identified lysosomal protein transmembrane 4 beta-35 (laptm4b-35) plays important roles in tumor progression and metastasis, while argininosuccinate synthetase (ass) provides arginine as an indispensable nutrient for hepatocellular carcinoma (hcc). the present study investigated the clinical significance of the coexpression of laptm4b-35 and ass in hcc patients on determining the prognosis. | 2011 | 21626328 |
| sildenafil restores cognitive function without affecting aß burden in an alzheimer's disease mouse model. | background and purpose: phosphodiesterase (pdes) 5 inhibitors regulate signaling pathways by elevating cgmp, which is a second messenger involved in processes of neuroplasticity. in the present study, the effect of the administration of the pde 5 inhibitor, sildenafil, on the pathological hallmarks of the alzheimer's disease and on memory-related behavior were investigated. experimental approach: sildenafil was administered to the tg2576 transgenic mouse model of alzheimer's disease and to age-m ... | 2011 | 21627640 |
| ass(2)cl-an arsenic(v) compound? formation, stability and structure of gaseous asscl and ass(2)cl-a combined experimental and theoretical study. | by reaction of solid as(4)s(4) with gaseous cl(2) at a temperature of 410 k gaseous asscl and ass(2)cl are formed. unexpectedly in ass(2)cl the arsenic is not of formal oxidation state +v but +iii: the molecular structure of ass(2)cl is arranged as a 1-chloro-dithia-arsirane and comprises an hitherto unknown ass(2) three-membered ring. thermodynamic data on asscl and ass(2)cl are obtained by mass spectrometry (ms). the experimental data are extended and confirmed by ab initio quantum chemical ca ... | 2011 | 21629882 |
| radiological anatomy of the donkey's foot: objective characterisation of the normal and laminitic donkey foot. | reasons for performing study: anatomical change within a laminitic foot is of diagnostic and prognostic importance. a lateromedial radiograph represents the current 'gold standard' by which these changes are identified. detection of anatomical change is dependent upon a priori knowledge of normality and subjective assessment alone may not identify modest change. normal baseline data is, therefore, needed against which objective comparisons can be made. there is little information regarding the r ... | 2011 | 21631583 |
| the role of working equines to livelihoods in current day campesino hill-slope communities in central mexico. | small-holder campesino agriculture is based on the diversified use of resources and off-farm work. working equines have a multifunctional character and sustain the diversification of livelihoods having different values as assets or providing services. the objective was to identify the role of working equines in current diversification strategies in the livelihoods of campesino families in a hill-slope community in central mexico within livelihoods analysis. thirty-one variables related to owners ... | 2011 | 21637993 |
| poppea's bath liquor: the secret proteome of she-donkey's milk. | donkey's milk is today categorized among the best mother's milk substitute for allergic newborns, due to its much reduced or absent allergenicity, coupled to excellent palatability and nutritional value. however, up to the present, only a handful of proteins had been characterized, just about the standard eight to ten major ones known in all types of milk. by exploiting the combinatorial peptide ligand library technology, and treating large volumes (up to 300ml) of defatted, de-caseinized (whey) ... | 2011 | 21645650 |
| alternative stable states and phase shifts in coral reefs under anthropogenic stress. | ecosystems with alternative stable states (ass) may shift discontinuously from one stable state to another as environmental parameters cross a threshold. reversal can then be difficult due to hysteresis effects. this contrasts with continuous state changes in response to changing environmental parameters, which are less difficult to reverse. worldwide degradation of coral reefs, involving "phase shifts" from coral to algal dominance, highlights the pressing need to determine the likelihood of di ... | 2011 | 21661558 |
| surveillance programme for important equine infectious respiratory pathogens in the usa. | the prevalence and epidemiology of important viral (equine influenza virus [eiv], equine herpesvirus type 1 [ehv-1] and ehv-4) and bacterial (streptococcus equi subspecies equi) respiratory pathogens shed by horses presented to equine veterinarians with upper respiratory tract signs and/or acute febrile neurological disease were studied. veterinarians from throughout the usa were enrolled in a surveillance programme and were asked to collect blood and nasal secretions from equine cases with acut ... | 2011 | 21676986 |
| human scca serpins inhibit staphylococcal cysteine proteases by forming classic "serpin-like" covalent complexes. | proteolytic enzymes secreted by staphylococcus aureus are considered important virulence factors. here, we present data showing that staphylococci-derived cysteine proteases (staphopains) are efficiently inhibited by squamous cell carcinoma antigen 1 (scca1), a serpin abundant on the epithelial surfaces. the high association rate constant (k(ass)) for inhibitory complex formation (1.9 +ù 10ôü¦ and 5.8 +ù10ôü¦ môü+-¦ sôü+-¦ for staphopain a and staphopain b interaction with scca1, respectively) a ... | 2011 | 21683261 |
| cascaded raman shifting of high-peak-power nanosecond pulses in asôéésôéâ and asôééseôéâ optical fibers. | we report efficient cascaded raman scattering of near-ir nanosecond pulses in large-core (65 ++m diameter) asôéésôéâ and asôééseôéâ optical fibers. raman scattering dominates other spectral broadening mechanisms, such as four-wave mixing, modulation instability, and soliton dynamics, because the fibers have large normal group-velocity dispersion in the spectral range of interest. with ~2 ns pump pulses at a wavelength of 1.9 ++m, four stokes peaks, all with peak powers greater than 1 kw, have be ... | 2011 | 21686017 |
| innovative zoning to support equine influenza eradication from new south wales, australia. | following detection of equine influenza (ei) in new south wales, a complete standstill was imposed the next morning on the movement of all horses and donkeys within the state. premises' biosecurity guidelines became progressively more stringent with time in an effort to stop local spread. the standstill was highly effective as a primary response to stop ei becoming widespread across australia, but did not prevent spread to properties contiguous to infected premises in areas of high horse density ... | 2011 | 21711306 |
| adventitious sounds identification and extraction using temporal-spectral dominance based features. | respiratory sound (rs) signals carry significant information about the underlying functioning of the pulmonary system by the presence of adventitious sounds (ass). although many studies have addressed the problem of pathological rs classification, only a limited number of scientific works have focused in the analysis of the evolution of symptom related signal components in joint time-frequency (tf) plane. this paper proposes a new signal identification and extraction method for various ass based ... | 2011 | 21712152 |
| vertebral artery injuries following cervical spine trauma: a prospective observational study. | purpose: the purpose of this study was to report on the incidence, diagnosis and clinical manifestation of vai following cervical spine injuries observed in a prospective observational study with a standardized clinical and radiographical protocol. methods: during a 16-year period, 69 (mean age: 43-á-¦-á20.7-áyears; 25 female, 44 male) of 599 patients had cervical spine injury suspicious for vai due to facet luxation and/or fractures extending into the transverse foramen. diagnosis and managemen ... | 2011 | 21717238 |
| mitochondrial genome sequence of the tibetan wild ass (equus kiang). | the tibetan wild ass, or kiang (equus kiang) is endemic to the cold and hypoxic (4000-7000-ám above sea level) climates of the montane and alpine grasslands of the tibetan plateau. we report here the complete nucleotide sequence of the e. kiang mitochondrial genome. our results show that e. kiang mitochondrial dna is 16,634-ábp long, and predicted to encode all the 37 genes that are typical for vertebrates. | 2011 | 21732718 |
| african horse sickness in the gambia: circulation of a live-attenuated vaccine-derived strain. | summaryafrican horse sickness virus serotype 9 (ahsv-9) has been known for some time to be circulating amongst equids in west africa without causing any clinical disease in indigenous horse populations. whether this is due to local breeds of horses being resistant to disease or whether the ahsv-9 strains circulating are avirulent is currently unknown. this study shows that the majority (96%) of horses and donkeys sampled across the gambia were seropositive for ahs, despite most being unvaccinate ... | 2011 | 21733265 |
| coagulation profiles of healthy andalusian donkeys are different than those of healthy horses. | coagulation disorders are frequently diagnosed, especially in hospitalized equidae, and result in increased morbidity and mortality. however, hemostatic reference intervals have not been established for donkeys yet. | 2011 | 21736621 |
| activation of pkr causes amyloid ß-peptide accumulation via de-repression of bace1 expression. | bace1 is a key enzyme involved in the production of amyloid ß-peptide (aß) in alzheimer's disease (ad) brains. normally, its expression is constitutively inhibited due to the presence of the 5'untranslated region (5'utr) in the bace1 promoter. bace1 expression is activated by phosphorylation of the eukaryotic initiation factor (eif)2-alpha, which reverses the inhibitory effect exerted by bace1 5'utr. there are four kinases associated with different types of stress that could phosphorylate eif2 ... | 2011 | 21738672 |
| space availability influence laterality in donkeys (equus asinus). | cerebral lateralization is the portioning of the cognitive functions between the two cerebral hemispheres. several factors, like embryological manipulations, light exposure, health conditions, sex and age can influence the left-right brain asymmetries and contribute to increasing the variability in the strength and direction of laterality within most species. we investigated the influence of an environmental constraint, namely space availability, as a new source of variation on laterality in an ... | 2011 | 21741459 |
| serum metal ion levels after rotating-hinge knee arthroplasty: comparison between a standard device and a megaprosthesis. | purpose: the effects of systemic metal ion exposure in patients with implants made of common prosthetic alloys continue to be a matter of concern. the aim of the study was to determine the measurement values of cobalt (co), chromium (cr) and molybdenum (mo) in serum following rotating-hinge knee arthroplasty. methods: blood was taken from 25 patients [mean follow-up 35 (range nine to 67) months] treated with megaprostheses (n=17) or standard rotating-hinge devices (n=8) and analysed using electr ... | 2011 | 21755331 |
| polymorphic organization of constitutive heterochromatin in equus asinus (2n = 62) chromosome 1. | in the karyotype of equus asinus (domestic donkey, 2n = 62), non-centromeric heterochromatic bands have been described in subcentromeric and telomeric positions. in particular, chromosome 1 is characterised by heterochromatic bands in the proximal region of the long arm and in the short arm; it has been shown that these regions are polymorphic in size. here we investigated the variation in the intensity and distribution of fluorescence signals observed on donkey chromosome 1 after in situ hybrid ... | 2011 | 21756256 |
| unexpected stable dimerisation of an anionic imidopyrrolecarboxylate in polar solution. | the imidopyrrolecarboxylate 3(-) unexpectedly forms stable dimers (k(ass) = 130 m(-1) in chcl(3)/dmso, 1?:?1, v/v) despite the fact that two anions have to interact. the dimer is more stable than an analogous neutral amidopyrrolecarboxylic acid dimer (k(ass) < 10 m(-1)) underlining the importance of charged h-bonds compared to neutral ones. | 2011 | 21761036 |
| aldosterone induces electrical remodeling independent of hypertension. | background: treatment of heart failure patients with aldosterone antagonists has been shown to reduce the occurrence of sudden cardiac death. therefore we aimed at determining the consequences of chronic exposure to aldosterone and the aldosterone antagonists eplerenone and spironolactone on the electrophysiological properties of the heart in a rat model. methods and results: male wistar rats were chronically treated (4weeks) with aldosterone (ald) via an osmotic minipump. spironolactone (spi) o ... | 2011 | 21764470 |
| nandrolone and stanozolol induce leydig cell tumor proliferation through an estrogen-dependent mechanism involving igf-i system. | several substances such as anabolic androgenic steroids (aas), peptide hormones like insulin-like growth factor-i (igf-i), aromatase inhibitors and estrogen antagonists are offered via the internet, and are assumed without considering the potential deleterious effects that can be caused by their administration. in this study we aimed to determine if nandrolone and stanozolol, two commonly used aas, could have an effect on leydig cell tumor proliferation and if their effects could be potentiated ... | 2011 | 21769864 |
| chromosomal assignment of six genes (eif4g3, hsp90, rbbp6, il8, tert, and terc) in four species of the genus equus. | we mapped six genes (eif4g3, hsp90, rbbp6, il8, tert, and terc) on the chromosomes of equus caballus, equus asinus, equus grevyi, and equus burchelli by fluorescence in situ hybridization. our results add six type i markers to the cytogenetic map of these species and provide new information on the comparative genomics of the genus equus. | 2011 | 21774619 |
| detection of cow milk in donkey milk by chemometric procedures on triacylglycerol stereospecific analysis results. | stereospecific analysis is an important tool for the characterization of lipid fraction of food matrices, and also of milk samples. the results of a chemical-enzymatic-chromatographic analytical method were elaborated by chemometric procedures such as linear discriminant analysis (lda) and artificial neural network (ann). according to the total composition and intrapositional fatty acid distribution in the triacylglycerol (tag) backbone, the obtained results were able to characterize pure milk s ... | 2011 | 21774859 |
| treating epilepsy: a review of polish historical sources. | the first surviving polish publications on epilepsy were written in the 16th and 17th centuries. many causes of epileptic seizures are quoted and they are divided into two categories: internal and external. internal causes (causa interna) include imbalance in the basic bodily humors, that is, yellow bile, black bile, phlegm, and blood. according to medieval writers, the principal cause of epilepsy was vapor, a damp, cold volatile substance originating in the excessive production of one of the ba ... | 2011 | 21775214 |
| pharmacogenetics of escitalopram and mental adaptation to cancer in palliative care: report of 18 cases. | aims and background. in palliative care, few data are available on the diagnosis and treatment of mood disorders and of difficulties of mental adaptation to cancer for patients in the advanced phases of the disease. ssri antidepressants are the treatment of choice; the 5-httlpr genetic polymorphism of the serotonin transporter (sert) has been shown in psychiatry to significantly determine the therapeutic response and the incidence of adverse effects. the aim of the present investigation has been ... | 2011 | 21789016 |
| successful treatment of equine sarcoids with cisplatin electrochemotherapy: a retrospective study of 48 cases. | reasons for performing study: sarcoids are the commonest form of equine skin tumour. several therapeutic measures have been described but none is considered to be universally effective. electrochemotherapy (ect) is a new anticancer therapy that utilises electrical field pulses to induce increased cell membrane permeability to antitumour hydrophilic drugs, such as cisplatin. the increased intracellular concentration of the drugs has a significant therapeutic benefit. the procedure has not been pr ... | 2011 | 21793876 |
| a gene catalogue of the euchromatic male-specific region of the horse y chromosome: comparison with human and other mammals. | studies of the y chromosome in primates, rodents and carnivores provide compelling evidence that the male specific region of y (msy) contains functional genes, many of which have specialized roles in spermatogenesis and male-fertility. little similarity, however, has been found between the gene content and sequence of msy in different species. this hinders the discovery of species-specific male fertility genes and limits our understanding about msy evolution in mammals. here, a detailed msy gene ... | 2011 | 21799735 |
| stability of behavioral estimates of activity-dependent modulation of pain. | temporal sensory summation of pain (tssp) is a proxy measure of windup in humans and results in increased ratings of pain caused by a repetitive, low-frequency noxious stimulus. aftersensations (ass) are pain sensations that remain after tssp has been induced. we examined the within-session and across-session variability in tssp and as estimation in healthy participants and in participants with exercise-induced muscle pain in order to determine whether the presence of pain affected the stability ... | 2011 | 21811390 |
| Colonization of turbot tissues by virulent and avirulent Aeromonas salmonicida subsp. salmonicida strains during infection. | Preventing disease outbreaks in cultured turbot Psetta maxima L. caused by Aeromonas salmonicida subsp. salmonicida (ASS) requires a better understanding of how this pathogen colonizes its host. Distribution of 1 virulent and 2 avirulent ASS strains in turbot tissues was investigated during early and late stages of infection following an immersion challenge. To track bacteria within the turbot, the ASS strains were tagged with green fluorescent protein (GFP). Both virulent and avirulent strains ... | 2011 | 21848125 |
| mri apparent diffusion coefficient reflects histopathologic subtype, axonal disruption, and tumor fraction in diffuse-type grade ii gliomas. | the apparent diffusion coefficient (adc) determined from mr diffusion tensor imaging (dti) has shown promise for distinguishing world health organization grade ii astrocytoma (as) from the more prognostically favorable grade ii oligodendroglioma (od). since mixed oligoastrocytomas (oas) with codeletions in chromosomes 1p and 19q confer prognoses similar to those of od, we questioned whether a previously determined adc-based criterion for distinguishing od and as would hold on an independent set ... | 2011 | 21865401 |
| Gasterophilosis: a major cause of rectal prolapse in working donkeys in Ethiopia. | A retrospective study was conducted to investigate the cause of rectal prolapse in working donkeys in Ethiopia. Analysis of data on rectal prolapse cases obtained from the Donkey Health and Welfare Project clinic at the School of Veterinary Medicine, Addis Ababa University, from 1995 to 2004 revealed that 83.6% (n?=?177) of the cases were associated with Gasterophilus nasalis. The rest 10.7% and 5.7% were associated with work-related (overloading) cause and diarrhoea, respectively. The mean and ... | 2011 | 21870062 |
| Characteristics of donkey spermatozoa along the length of the epididymis. | In mammals, the epididymis has numerous interrelated functions including absorptive and secretory activity that affect luminal environment and cell membrane, and the maturation and storage of sperm. Spermatozoa acquire their motility and fertilizing ability during their passage through the epididymis and the motility of epididymal spermatozoa should be a balance between the maturation of flagellum and the inhibition of the flagellar machinery. In this study maturational change in sperm character ... | 2012 | 21872312 |
| Pig specific vascular anatomy allows acute infrarenal aortic occlusion without hind limb ischemia and stepwise occlusion without clinical signs. | In a porcine, aortic graft model we found 5 animals to develop and survive unnoticed, complete infrarenal aortic occlusion and 2 pigs with an acute occlusion but rather unspecific clinical symptoms. We investigated the pigs' vascular system to classify the anatomic capabilities to compensate for an acute abdominal aortic occlusion. | 2011 | 21876245 |
| comparative evaluation of three commercially available complement fixation test antigens for the diagnosis of glanders. | the sensitivity and specificity of three commercially available complement fixation test (cft) antigens from c.c.pro (c.c.pro), central veterinary institute of wageningen ur (cidc) and the united states department of agriculture (usda) were comparatively evaluated by testing 410 sera collected from glanders-endemic and non-endemic areas (200 true-negative randomly collected sera and 210 sera collected from experimentally immunised animals (12 rabbits, 19 horses), clinically positive (135) and cu ... | 2011 | 21896565 |
| the relationship of arginine deprivation, argininosuccinate synthetase and cell death in melanoma. | it has been shown that melanoma cells do not express argininosuccinate synthetase (ass) and therefore are unable to synthesize arginine from citrulline. depleting arginine using pegylated arginine deiminase (adi-peg20) results in cell death in melanoma but not normal cells. this concept was translated into clinical trial and responses were seen. however, induction of ass expression does occur which results in resistance to adi-peg20. we have used 4 melanoma cell lines to study factors which may ... | 2007 | 21901069 |
| trichophyton bullosum: a new zoonotic dermatophyte species. | we report the first human case of dermatophytosis caused by trichophyton bullosum in a 21-year-old male who had a skin lesion located on his forearm. the dermatophyte was isolated in culture and further identified by sequence analysis of internal transcripted spacer regions. the species t. bullosum is a zoophilic dermatophyte rarely isolated from the coat of horses in africa and asia. in the present case, it was probably transmitted by contact with an infected donkey in a rural area in france. a ... | 2011 | 21905949 |
| comparative morphometric and glycohistochemical studies on the epididymal duct in the donkey (equus asinus) and dromedary camel (camelus dromedarius). | the present study was undertaken to compare morphometric and glycohistochemical differences in the epididymal duct of the donkey and the dromedary camel. paraffin-embedded sections from the different regions of the duct (caput, corpus and cauda) of both species were stained conventionally for general histology and histomorphometry and also with fluorescein isothiocyanate (fitc) conjugated lectins for glycohistochemical mapping. morphometric data (means±se) showed that the luminal diameter was wi ... | 2011 | 21906788 |
| x-ray absorption and photoelectron spectroscopic study of the association of as(iii) with nanoparticulate fes and fes-coated sand. | iron sulfide (fes) has been demonstrated to have a high removal capacity for arsenic (as) in reducing environments. however, fes may be present as a coating, rather than in nanoparticulate form, in both natural and engineered systems. frequently, the removal capacity of coatings may be different than that of nanoparticulates in batch systems. to assess the differences in removal mechanisms between nanoparticulate fes and fes present as a coating, the solid phase products from the reaction of as( ... | 2011 | 21911241 |
| potential risk of zoonotic transmission from young swine to human: seroepidemiological and genetic characterization of hepatitis e virus in human and various animals in beijing, china. | the aim of this study was to further investigate the prevalence of infection and genotype of hepatitis e virus (hev) among different species of animals, people whose works are related to pigs and the general population in the suburb of beijing, china. serum and faecal samples were collected from 10 animal species and humans. anti-hev was detected by enzyme immunoassays (eia); hev rna was amplified by reverse transcription-nested polymerase chain reaction (rt-npcr) method. pcr products were clone ... | 2011 | 21914080 |
| arginine or citrulline associated with a statin stimulates nitric oxide production in bovine aortic endothelial cells. | nitric oxide (no) is an antiatherogenic vasodilator synthesized from arginine and, indirectly, from citrulline through argininosuccinate synthase (ass) and argininosuccinate lyase (asl). hypercholesterolemia-induced atherosclerosis is usually treated by statins, which decrease cholesterolemia and increase endothelial no synthase (enos) activity. therefore, a treatment associating a statin with arginine or citrulline could be more efficient than statin alone. the aim of this study was to optimize ... | 2011 | 21914450 |
| Co-expression of Arabidopsis thaliana phytochelatin synthase and Treponema denticola cysteine desulfhydrase for enhanced arsenic accumulation. | Arsenic is one of the most hazardous pollutants found in aqueous environments and has been shown to be a carcinogen. Phytochelatins (PCs), which are cysteine-rich and thio-reactive peptides, have high binding affinities for various metals including arsenic. Previously, we demonstrated that genetically engineered Saccharomyces cerevisiae strains expressing phytochelatin synthase (AtPCS) produced PCs and accumulated arsenic. In an effort to further improve the overall accumulation of arsenic, cyst ... | 2012 | 21915851 |
| relationships between the dynamics of iatrogenic dna damage and genomic design in mammalian spermatozoa from eleven species. | the dynamic onset of dna fragmentation in mammalian sperm populations varies widely in different species when the spermatozoa are incubated in vitro at body temperature for several hours, and recent studies have shown that the dynamic rate of dna fragmentation within a species has considerable predictive value in terms of fertility. the reasons for such variation are unclear, but here we show that differences in protamine sequence and identity could be partially responsible. sets of 10 normal se ... | 2011 | 21919111 |
| the epidemiology of cranio-facial injuries caused by animals in southern-central china. | a clinical investigation was conducted to demonstrate the epidemiology of cranio-facial injuries inflicted by animals in southern-central part of china-the world's most populous eastern country. it consisted of a retrospective study of 149 patients and was carried out in our department. all the patients were attacked by animals, such as buffalo, cattle, donkey, horse, dog, cat, and rat. there were 91 males and 58 females patients, aged from 5 to 65 years. 113 patients were from rural areas, and ... | 2011 | 21925891 |
| cavity enhanced stimulated brillouin scattering in an optical chip for multiorder stokes generation. | we report the first demonstration of on-chip cascaded stimulated brillouin scattering (sbs). cascaded sbs is characterized in a 4 cm long chalcogenide (as₂s₃) rib waveguide where the end facet reflections provide a monolithic fabry-perot (fp) resonator. the presence of the fp cavity reduces the brillouin gain threshold, which enables observation of cascaded sbs at reduced pump powers. we observe up to three orders of stokes waves in the backscattered signal at a coupled peak power of 1.34 w. ant ... | 2011 | 21931433 |
| stable overexpression of arginase i and ornithine transcarbamylase in hepg2 cells improves its ammonia detoxification. | hepg2 is an immortalized human hepatoma cell line that has been used for research into bioartificial liver systems. however, a low level of ammonia detoxification is its biggest drawback. in this work, a recombinant hepg2 cell line with stable overexpression of human arginase i (hargi) and human ornithine transcarbamylase (hotc), hepg2/(hargi + hotc)4, was developed using a eukaryotic dual gene expression vector pbudce4.1. □ the hargi and hotc enzymatic activity in hepg2/(hargi + hotc)4 cells we ... | 2011 | 21938740 |
| cytotoxicity and glycan-binding profile of a d-galactose-binding lectin from the eggs of a japanese sea hare (aplysia kurodai). | a divalent cation-independent 16 kda d-galactose binding lectin (akl-2) was isolated from eggs of sea hare, aplysia kurodai. the lectin recognized d-galactose and d-galacturonic acid and had a 32 kda dimer consisting of two disulfide-bonded 16 kda subunits. eighteen n-terminus amino acids were identified by edman degradation, having unique primary structure. lectin blotting analysis with horseradish peroxidase-conjugated lectins has shown that akl-2 was a glycoprotein with complex type oligosacc ... | 2011 | 21953532 |
| My fat ass: a miniature donkey teaches lessons on helping patients fight obesity. | 2011 | 21957814 | |
| ultrasonographic features of the mule embryo, fetus and fetal-placental unit. | the aim of this study was to establish baseline ultrasound data concerning the mule conceptus during gestation. ten multiparous trotter mares were artificially inseminated with chilled semen from an amiatino jack donkey. daily transrectal ultrasonography was carried out from the day of ovulation until day 50 of gestation to determine the following: first detection of the embryonic vesicle (ev), mobility phase, ev diameter, day of ev fixation, changes in ev shape, date of yolk sac regression and ... | 2011 | 21958639 |
| lactation curve and effects of milking regimen on milk yield and quality, and udder health in martina franca jennies (equus asinus). | three experiments were conducted on martina franca jennies. experiment 1 tested wood's model for evaluating the lactation curve. data from the entire lactation period of 12 jennies were used. the results showed that wood's model was able to recognize the shape of the lactation curve from pooled data (r(2) = 0.11; p < 0.01), with the lactation peak occurring at 48 d. individual curves showed wide variability. experiment 2 aimed to evaluate the effects of the daily number of milkings (1, 3, or 6) ... | 2011 | 21965450 |
| ethanolamine oleate in resistant idiopathic achalasia: a novel therapy. | idiopathic achalasia (ia) is a chronic disease without definite therapy. ethanolamine oleate (eo) has multiple biological effects, including inflammatory activities. we investigated the efficacy of eo injection in selected patients with ia. | 2011 | 21971376 |
| occurrence of water-borne enteric viruses in two settlements based in eastern chad: analysis of hepatitis e virus, hepatitis a virus and human adenovirus in water sources. | hepatitis e virus (hev) is a common cause of water-borne acute hepatitis in areas with poor sanitation. in 2004 an outbreak of hev infection affected around 2,000 people in eastern chad (dar sila). this paper describes the decrease in the incidence of acute jaundice syndrome (ajs) from 2004 until 2009 when a mean incidence of 0.48 cases/1,000 people/year was recorded in the region. outbreaks of ajs were identified in some of the camps in 2007 and 2008. moreover, water samples from drinking water ... | 2011 | 21976198 |
| sources and leaching of manganese and iron in the saigon river basin, vietnam. | high concentrations of manganese and iron in the saigon river are major problems for the water supply in ho chi minh city (hcmc), viet nam. to identify their sources and leaching processes, we surveyed water quality along the saigon river and ran batch leaching tests using soil and sediment samples. two important leaching processes were identified: acidic leaching from acid sulfate soil (ass) in the middle reaches of the river, and mn dissolution and fe reduction from sediments in the downstream ... | 2011 | 21977643 |
| synthesis, characterisation and biological evaluation of copper and silver complexes based on acetylsalicylic acid. | metalcarbonyl complexes with ligands derived from acetylsalicylic acid demonstrated high cytotoxic potential against various tumor cell lines and strong inhibition of the cyclooxygenase enzymes cox-1 and 2. in this study we tried to achieve comparable effects with [alkyne]silver or copper trifluoromethanesulfonate complexes which are more hydrophilic then the uncharged metalcarbonyl derivatives. all compounds were evaluated for growth inhibition against breast (mcf-7, mda-mb 231) and colon cance ... | 2011 | 21984018 |
| gastric and enteric phytobezoars caused by ingestion of persimmon in equids. | case description-13 equids (10 horses, 2 donkeys, and 1 pony) were examined for signs of colic (n = 7), weight loss (6), anorexia (3), and diarrhea (2). ten equids were evaluated in the fall (september to november). seven equids had a history of persimmon ingestion. clinical findings-a diagnosis of phytobezoar caused by persimmon ingestion was made for all equids. eight equids had gastric persimmon phytobezoars; 5 had enteric persimmon phytobezoars. gastroscopy or gastroduodenoscopy revealed evi ... | 2011 | 21985354 |
| Effect of equestrian therapy and onotherapy in physical and psycho-social performances of adults with intellectual disability: a preliminary study of evaluation tools based on the ICF classification. | Purpose: To assess the effects of equestrian rehabilitation (ER) and onotherapy (Ono) on physical and psycho-social performances of subjects affected by intellectual disability (ID), and to develop a measurement tool based on the International Classification of Functioning Disability and Health-Children and Youth (ICF-CY). Methods: A tool based on the ICF-CY classification was designed to evaluate subjects undergoing equine rehabilitation within a bio-psychosocial approach. A simplified version ... | 2012 | 21988646 |
| Identification of meat species by PCR-RFLP of the mitochondrial COI gene. | Meat authenticity verification is pertinent for economical, religious or public health concerns. The present study investigates the use of PCR-RFLP of a part of the mitochondrial cytochrome c oxidase subunit 1 (COI) gene for identification of species origin of raw meat samples of cow, chicken, turkey, sheep, pig, buffalo, camel and donkey. PCR yielded a 710-bp fragment in all species. The amplicons were digested with seven restriction endonucleases (Hind II, Ava II, Rsa I, Taq I, Hpa II, Tru 1I ... | 2012 | 21996288 |
| differences between epididymal and ejaculated sperm characteristics in donkey. | spermatozoa acquire their motility and fertilizing ability during their passage through the epididymal canal. in the epididymal caput and corpus spermatozoa undergo several biochemical and metabolic changes while the cauda of the epididymis should be considered as the primarily site for storage of the spermatozoa. in the horse spermatozoa from cauda epididymis were collected and frozen, and the fertility of semen assessed. however, no studies have detailed semen characteristics of spermatozoa co ... | 2011 | 21996580 |
| Corneal penetration of topical and subconjunctival bevacizumab. | To investigate the ability of bevacizumab to penetrate the cornea after topical application or subconjunctival injection. | 2011 | 22003112 |
| genetic differences in the serum proteome of horses, donkeys and mules are detectable by protein profiling. | although horses and donkeys belong to the same genus, their genetic characteristics probably result in specific proteomes and post-translational modifications (ptm) of proteins. since ptm can alter protein properties, specific ptm may contribute to species-specific characteristics. therefore, the aim of the present study was to analyse differences in serum protein profiles of horses and donkeys as well as mules, which combine the genetic backgrounds of both species. additionally, changes in ptm ... | 2011 | 22005420 |
| Association constants and distribution functions for ion pairs in binary solvent mixtures: application to a cyanine dye system. | The computations of the association constants K(ass) were performed at the microscopic level for the ion pair Cy(+)I(-) composed of the complex cyanine dye cation Cy(+) coupled to the negative iodine counterion. The wide array of K(ass) values is arranged by a variation of the composition of the binary solvent mixtures toluene/dimethylsulfoxide with the accompanying change of the solvent polarity. The potentials of mean force (PMFs) are calculated for a set of interionic separations R in the Cy( ... | 2011 | 22010723 |
| effects of transcranial direct current stimulation of the primary sensory cortex on somatosensory perception. | transcranial direct current stimulation (tdcs) is able to modify cortical excitability and activity in humans. | 2011 | 22032740 |
| Psychological essentialist reasoning and perspective taking during reading: A donkey is not a zebra, but a plate can be a clock. | In an eyetracking study, we examined whether readers use psychological essentialist reasoning and perspective taking online. Stories were presented in which an animal or an artifact was transformed into another animal (e.g., a donkey into a zebra) or artifact (e.g., a plate into a clock). According to psychological essentialism, the essence of the animal did not change in these stories, while the transformed artifact would be thought to have changed categories. We found evidence that readers use ... | 2011 | 22037846 |
| Overexpression of histidine-rich calcium binding protein in equine ventricular myocardium. | Histidine-rich calcium binding protein (HRC) is a high capacity, low affinity Ca(2+) binding protein, specifically expressed in striated muscles of mammals. In rabbit skeletal and cardiac muscles, HRC binds to sarcoplasmic reticulum (SR) membranes via triadin, a junctional SR protein. Recently, a potential role in heart failure and arrhythmogenesis has been assigned to HRC due to its activity as regulator of SR Ca(2+) uptake and Ca(2+) release. HRC might play a particularly relevant role in the ... | 2011 | 22040806 |
| centromere repositioning in mammals. | the evolutionary history of chromosomes can be tracked by the comparative hybridization of large panels of bacterial artificial chromosome clones. this approach has disclosed an unprecedented phenomenon: 'centromere repositioning', that is, the movement of the centromere along the chromosome without marker order variation. the occurrence of evolutionary new centromeres (encs) is relatively frequent. in macaque, for instance, 9 out of 20 autosomal centromeres are evolutionarily new; in donkey at ... | 2012 | 22045381 |
| Large platelet aggregates in endoscopic ultrasound-guided fine-needle aspiration of the pancreas and peripancreatic region: A clue for the diagnosis of intrapancreatic or accessory spleen. | Intrapancreatic and intraabdominal accessory spleens (IPIASs) are rarely encountered in endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) biopsies. However, as incidentally discovered IPIAS can mimic a benign or malignant pancreatic neoplasm on imaging studies, a definitive diagnosis made by EUS-FNA can avert an unnecessary surgical intervention or additional radiologic follow-up. We report five cases of intrapancreatic splenules and one case of accessory spleen (AS) in which a defin ... | 2011 | 22045629 |
| PARTIAL DELETION OF ARGININOSUCCINATE SYNTHASE PROTECTS FROM PYRAZOLE PLUS LIPOPOLYSACCHARIDE-INDUCED LIVER INJURY BY DECREASING NITROSATIVE STRESS. | Background & Aim: Argininosuccinate synthase is the rate-limiting enzyme in the urea cycle. Along with nitric oxide synthase-2, argininosuccinate synthase endows cells with the L-citrulline/nitric oxide salvage pathway to continually supply L-arginine from L-citrulline for sustained nitric oxide generation. Because of the relevant role of nitric oxide synthase-2 in liver injury, we hypothesized that down-regulation of argininosuccinate synthase could decrease the availability of intracellular su ... | 2011 | 22052013 |
| increased expression of aryl hydrocarbon receptor and interleukin 22 in patients with allergic asthma. | we sought to determine whether the aryl hydrocarbon receptor (ahr) and interleukin (il)-22 may be involved in the pathogenesis of the peripheral blood mononuclear cells (pbmcs) in allergic asthmatic patients and whether their expression may be related to the severity of the disease. | 2011 | 22053597 |
| differentiation of raw meat from phylogenically related species by enzyme-linked immunosorbent assay. | a method, based on enzyme-linked immunosorbent assay (elisa), has been developed for differentiating raw meat from closely related species of economic importance. by visual assessment 0·1% donkey in horse, 0·1% goat in sheep and 1% buffalo in beef may be detected. the technique is rapid and simple to perform and could be used in abattoirs and coldstores with results being available within 1 h. | 1985 | 22054500 |
| differentiation of meat from horse, donkey and their hybrids (mule/hinny) by electrophoretic separation of albumin. | meat from the species horse, donkey and their hybrids, mule/hinny, can be reliably identified by determination of genetic variants of serum albumin by starch gel electrophoresis of meat extracts. staining of the starch gel for carboxylesterase activity permits differentiation of most horses from donkeys while mules/hinnies cannot be distinguished from horses by their esterase activity alone. | 1987 | 22054691 |
| embryo quality and transcervical technique are not the limiting factors in donkey embryo transfer outcome. | embryo transfer (et) in the donkey resulted in a very low recipient pregnancy rates. the aim of these studies was to investigate if nonsurgical transfer techniques or donkey embryo quality affect donkey recipient pregnancy failure. in study 1, the impact of transfer technique was investigated by evaluating if cervical catheterization is associated with prostaglandin release and suppression of luteal function and if donkey recipients would become pregnant after nonsurgical transfer of horse embry ... | 2011 | 22056016 |