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metabolism during the postinjury period. 20134906806
[scanning of the distal perfusion pressure in skin and muscle with 133 xenon in estimation of the pressure situation in pregangrene--gangrene]. 20164913102
[the medicine of carlos de sigüenza and sister juana inés de la cruz. contribution to the baroque thought of 17th century mexico]. 20164913425
marine and estuarine pollution. 20164914106
[glucagon and gastric secretion]. 20164914558
durability of prosthetic heart valves. 20164926359
heterogeneity of phenotypic expression in a family with swiss-type agammaglobulinemia: observations on the acquisition of agammaglobulinemia. 20164930796
degradation products and the role of coagulation in "persistent" glomerulonephritis. 20164931741
short-term cultures of mouse marrow cells separated by velocity sedimentation. 19714942466
the utilization of prolyl peptides by escherichia coli.peptides that have an n-terminal proline residue are taken up by escherichia coli and are degraded by intracellular peptidases. a mutant that is unable to transport oligopeptides with n-terminal alpha-amino acids is also unable to transport the peptides with n-terminal proline. dipeptides and oligopeptides can prevent the uptake of the corresponding prolyl peptides and the converse competitive interactions are also observed. although the peptide alpha-amino group is essential to the process of p ...19714942538
[problems of anesthesia and resuscitation]. 19714945852
on the stereochemical basis of enzyme action: lessons from lysozyme. 19714949243
[early postoperative rehabilitation after maxillary resection]. 20164951118
operant discrimination of an interoceptive stimulus in rhesus monkeys.five rhesus macaques monkeys surgically prepared with thiry small intestinal (jejunum) loops and implanted brain electrodes were restrained in primate chairs and kept on 23-hr deprivation-feeding cycle. after being trained to press a lever for sugar pills on an fr 25 schedule of reinforcement, a discrimination training procedure was established. lever presses were reinforced during the s(d)-a non-aversive mechanical stimulus applied to the internal walls of the thiry loop by rhythmic inflation-d ...19654954822
pyriformsinusosotomy. a useful technique for temporary or permanent tube feeding. 20164959520
the interaction patterns of combined antibacterial agents. experiments with two agardiffusion methods. 19664959585
rejection of the generic name dendrocystis rees, 1962, and its replacement by arborocystis nov.nom. protozoa: gregarinomorpha. 20164960245
identification of host and host antibodies from mosquito blood meals. 19674962027
[aspects of long term care. 1]. 20164971091
[comparative study of some technics for determination of transferrin in the blood]. 20164976288
[penimepicycline (hydrocycline biagini) in surgery]. 19694977341
no excuse for rh failure. 20164981721
nondialyzable urinary hydroxyproline as an index of bone collagen formation. 20164983851
[sensitization by metabolic inhibitors of isolated intestine of rats to the effects of sympathomimetics. effects of fluoro-acetate and sodium mitride]. 19704987116
clinical trial of clomacran phosphate (skf-14336) in chronic psychotic male patients. 20164987347
[pharmacologic tests for evaluation of the state of the pulmonary vessels in patients with congenital heart defects and severe pulmonary hypertension]. 20164999544
is jump to population-explosion bandwagon justified? 20165009981
impact of efforts to increase participation in repetitive screenings for early breast cancer detection. 20165011163
steroid therapy in tonsillectomy. 20155014392
[changes in plasma lipids in normal subjects in relation to age and sex. 3. total lipids, triglycerides, phospholipids, alpha- and beta-lipoproteic cholesterol and single nefa (c16-c18) in pre-senile subjects]. 20165030359
[diagnosis and therapy of chronic septic diseases]. 20165034424
the pragmatic utilization of the p-k phenomenon. 20165039530
preparation of hepatic microsomal fraction for drug metabolism studies by rapid decompression homogenization. 19725041006
rheomacrodex in the prevention of intraperitoneal adhesions. experimental work in cats. 19725042437
[2 cases of hyperlipemia observed in dakar]. 20165047448
[facilitation of labor]. 20165047589
effects of overfeeding on lipid and carbohydrate metabolism in lean young adults. 20165047918
lightness, embeddedness, and contrast. 20075054071
relationship of rumen volatile fatty acids to type of grain,sorghum grain processing method and feedlot performance. 19725055758
thin-layer chromatographic separation of the diphenylindenonesulphonyl derivatives of amino acids. 20165056240
idiopathic thrombocytopenic purpura. an unusual pregnancy complication. 20165061743
antigen recognition by t lymphocytes. thymus and marrow dependence of spontaneous rosette forming cells in the mouse. 19725061826
the structure of hemopeptide 1-65 from cytochrome c. 20165062022
temperature dependence of chloride, bromide, iodide, thiocyanate and salicylate transport in human red cells.1. the temperature dependence of the steady-state self-exchange of chloride between human red cells and a plasma-like electrolyte medium has been studied by measuring the rate of (36)cl(-) efflux from radioactively labelled cells. between 0 and 10 degrees c the rate increased by a factor of eight corresponding to an arrhenius activation energy of 33 kcal/mole.2. the rate of chloride exchange decreased significantly in experiments where 95% of the chloride ions in cells and medium were replaced b ...19725071931
the economics of medical education--national and international. 20165072222
[occurrence of nose tumors in cattle]. 19725073098
[gamma glutamyl carboxypeptidase from chicken pancreas]. 19725073874
[subphrenic abscess and its x-ray differential diagnosis]. 20165076712
coloboma of the iris and choroid and retinal detachment in oculo-auricular dysplasia (goldenhar syndrome). 20165076735
properties and purification of n-acetylmuramyl-l-alanine amidase from staphylococcus aureus h.the principal autolytic enzyme activity of the cell sap of staphylococcus aureus h has been purified 400-fold. it is an n-acetylmuramyl-l-alanine amidase. this enzyme has a molecular weight of 8 to 10 x 10(5), a ph optimum of 7.3, an ionic strength optimum of 0.16 m and a k(m) of 10(-3)m murein repeating units.19725086664
ultrastructure of the thyrotrophic cell in the pars distalis of the lizard. 20165087951
blood distribution through the lung after pneumonectomy: a quantitative assessment by 131-i. 20165091637
[reaction of tricarbethoxymethane. v. amidoesters]. 20165093140
[a case report of vibrio vulnificus infection with successful treatment]. 19846086784
siderophore production by vibrio vulnificus.previous studies in our laboratory, as well as clinical evidence, have suggested that increased iron levels in the host may be important in infections caused by the halophilic pathogen vibrio vulnificus. to study iron acquisition, we induced siderophore production by growth in a low-iron medium, and biochemical testing indicated the production of both hydroxamate- and phenolate-type siderophores. the siderophores were extracted from growth filtrates with ethyl acetate (for phenolates) and phenol ...19836223882
collagenolytic activity of vibrio vulnificus: potential contribution to its invasiveness.vibrio vulnificus (lactose-positive vibrio) produced collagenase when grown in 2% synthetic sea salts supplemented with hydrolyzed casein. the addition of collagen or peptone to the medium increased the level of collagenase production. collagenase activity was inhibited by edta but not by fetal calf serum.19826279515
[a case of hepatoma associated with vibrio vulnificus bacteremia and its bacteriological findings]. 19826290579
vibrio vulnificus septicemia. isolation of organism from stool and demonstration of antibodies by indirect immunofluorescence.vibrio vulnificus was isolated from blood and stool cultures from a 65-year-old man who had underlying alcoholic liver disease. the patient had eaten raw oysters the day before he became ill. to our knowledge, this is the first published report of isolation of the organism from stool in a patient with primary septicemia, and it provides support for epidemiologic studies suggesting that the infection is acquired through the gastrointestinal tract by eating raw seafood containing the organism. it ...19836340632
vibrio hand infections: a case report and review of the literature.a case of vibrio vulnificus infection of the hand is presented. the role of vibrio species as primary pathogens in infections associated with exposure to a marine environment is discussed.19846386958
[case of bacteremic phlegmon due to vibrio vulnificus]. 19836420485
protection of mice against vibrio vulnificus disease by vaccination with surface antigen preparations and anti-surface antigen antisera.vaccination of mice with either formalin-killed cells or cell extracts of a virulent strain and a weakly virulent strain of vibrio vulnificus or with rabbit antisera (as) against the formalin-killed cells and cell extracts protected against the virulent strain of v. vulnificus. however, the virulent strain vaccines and as elicited a significantly stronger immune response than the weakly virulent strain vaccines and as. adsorption of the as with either the homologous or heterologous formalin-kill ...19846469346
halophilic vibrio species from seafish in senegal.sucrose-positive and sucrose-negative halophilic vibrio species at counts of up to 10(7)/100 g were isolated from muscles tissue in 27 and 43%, respectively, of 128 seafish from coastal waters in senegal. vibrio parahaemolyticus, including 21% urease-positive strains, was the most common isolate, followed by vibrio alginolyticus, vibrio vulnificus, vibrio damsela, and vibrio fluvialis.19846476829
nucleotide base sequence of vibrionaceae 5 s rrna.nucleotide base sequences of 5 s rrnas isolated from vibrio vulnificus, vibrio anguillarum, and aeromonas hydrophila were determined. comparisons among these and sequences of 5 s rrnas from other species of vibrionaceae provide information useful in the evaluation of the evolution of bacterial species.19846479333
resistance of vibrio vulnificus to serum bactericidal and opsonizing factors: relation to virulence in suckling mice and humans.vibrio vulnificus causes soft-tissue infections, gastrointestinal disease, and severe sepsis in humans. bacterial and host factors in virulence have remained poorly defined. we found that blood culture isolates of v. vulnificus were completely resistant to the bactericidal effects of 10% normal human serum, in contrast to soft-tissue and environmental isolates that showed a mean 2.6 log10 decline during 120 min of incubation. following opsonization by 10% normal human serum, mean uptake of blood ...19846481186
vibrio vulnificus endometritis.vibrio vulnificus most frequently causes wound infections contracted after exposure to seawater or primary septicemias resulting from the consumption of raw oysters. we report a case of endometritis caused by v. vulnificus. the infection was apparently acquired during the act of sexual intercourse in seawater in an area in which v. vulnificus has been frequently isolated. the efficacy of treatment with an antimicrobial regimen which included tetracycline is discussed.19846490813
necrotising fasciitis caused by vibrio vulnificus.a case of necrotising fasciitis caused by vibrio vulnificus is described. the need for early recognition and aggressive surgical treatment are highlighted, and the necrotising infections due to v vulnificus described in the published work are reviewed.19846501592
evidence for the presence of a capsule in vibrio vulnificus.vibrio vulnificus strain fcc, isolated from a patient with a wound infection, and reference strain atcc 27562, were examined by electron microscopy for the presence of capsules. both strains had a layer heavily stained with ruthenium red. the number of stained cells was high in strain fcc and low in strain atcc 27562. the proportion of stained cells correlated with virulence against mice and with susceptibility to the bactericidal activity of normal human serum. rapid freezing and substitution f ...19846512503
on the serology of vibrio vulnificus.the serology of 70 strains of vibrio vulnificus was studied. seven o-antigenic groups were defined among them and it was shown that the h antigens of all the strains were identical. a heat-labile masked antigen, which inhibits o agglutination, was found in some strains. as all o antisera for v. vulnificus contained some r antibody, all diagnostic o sera must be absorbed with r organisms before use.19846536784
vibrio vulnificus. a gastronomic hazard. 19836572281
spectrum of vibrio infections in a gulf coast community.infection with vibrio species was diagnosed in 23 patients over a 10-year period in a gulf coast community. species isolated were vibrio vulnificus, v. cholerae, v. parahaemolyticus, and v. alginolyticus. clinical presentations included diarrhea, wound infection, and bacteremia. gastrointestinal tract infection was infrequently diagnosed, despite the routine use of stool culture media appropriate for vibrio isolation. bacteremic infections were severe and occurred only in patients with underlyin ...19836625378
[vibrio vulnificus]. 19836635466
differential complement activation and susceptibility to human serum bactericidal action by vibrio species.the ability of vibrio vulnificus to resist human serum bactericidal action and to activate human complement was compared with similar cultures of vibrio cholerae and vibrio parahaemolyticus. both v. vulnificus and v. parahaemolyticus had similar survival rates in sera and were much more resistant to killing than was v. cholerae. in contrast, v. vulnificus activated significantly less serum complement than did v. cholerae and v. parahaemolyticus. the relative ability of v. vulnificus to survive i ...19836642665
[fatal vibrio vulnificus infection in a patient with aplastic anemia].the patient was a 59-year-old man who had been in hospital suffering from aplastic anemia with transfusion hemosiderosis. sudden onset of weakness, shaking chills and headache was observed after his staying out overnight on july 25, 1981. his temperature was 39.3 degrees c and he complained of abdominal pain and abdominal distension. his blood pressure dropped to a dangerous level and tonic convulsions that had begun in the upper body gradually extended to the whole body and he died 23 hours aft ...19836679624
comparative studies and laboratory diagnosis of vibrio vulnificus, an invasive vibrio sp.vibrio vulnificus was isolated from a bacteremic patient. this strain, together with other isolates of v. vulnificus, was compared with v. alginolyticus, v. fluvialis, and v. parahaemolyticus with regard to growth characteristics on enteric agar media (enabling isolation and identification) and production of exoenzymes which could correlate with invasive potential. v. vulnificus grew well on macconkey. endo, xylose-lysine deoxycholate, and hektoen enteric agar plates. because v. vulnificus colon ...19846699140
wound infections caused by vibrio vulnificus, a marine vibrio, in inland areas of the united states.vibrio vulnificus is a halophilic marine vibrio which may produce infection in wounds exposed to seawater or raw shellfish. the centers for disease control has received two isolates from wounds exposed to inland waters, a new mexico creek and an oklahoma reservoir. halophilic organisms were recovered from both the creek and the reservoir, and the water in both sites was found to be brackish. both clinical isolates of v. vulnificus grew in salt concentrations as low as those found in the creek an ...19846699148
cytolytic activity and virulence of vibrio damsela.a correlation was observed between the ability of 19 isolates of vibrio damsela, a halophilic bacterium recently recognized as a human pathogen, to cause disease in mice and to produce large amounts of a cytolytic toxin in vitro. the yield of toxin in the culture supernatant fluids was optimal during the mid- and late-logarithmic phases of growth in medium containing 0.5% na+ ion, was stable during the stationary growth phase, and was significantly reduced in culture medium containing greater th ...19846715036
clinical features and an epidemiological study of vibrio vulnificus infections.vibrio vulnificus, a recently described halophilic vibrio species, has been isolated from the blood, wounds, and other skin lesions of patients with primary sepsis or wound infections. because no study of risk factors for infections with v vulnificus has been reported, a case-control study was performed with the 30 patients from whom v vulnificus isolates were recently submitted to the centers for disease control (atlanta, georgia). patients with primary sepsis were more likely than controls to ...19846725989
role of heme compounds and haptoglobin in vibrio vulnificus pathogenicity.an induced peritonitis model was employed in mice to determine whether heme-containing molecules enhance the lethality of infections by vibrio vulnificus. the lethality of intraperitoneal (ip) inocula of the bacteria was increased by concurrent injections (ip) of hemoglobin, methemoglobin, or hematin, but not by myoglobin. similar results were obtained in mice with phenylhydrazine-induced hemoglobinemia, in which after ip injections of v. vulnificus, a direct correlation between lethality and le ...19846746093
extracellular phospholipase a2 and lysophospholipase produced by vibrio vulnificus.phospholipase a2 and lysophospholipase activities were detected in the culture supernatant fluids of a virulent strain of vibrio vulnificus. the phospholipase a2 was inactivated by heating at 56 degrees c for 30 min, had an apparent molecular weight of greater than or equal to 80,000 (estimated by gel filtration with sephadex g-75), and a pi of ca. 5.0. phospholipid hydrolysis was unaffected by ca2+ or ethylene glycol-bis(beta-aminoethyl ether)-n,n-tetraacetic acid and was optimal at ph 5.0 to 5 ...19846746100
vibrio vulnificus septicaemia.a patient, who had been receiving treatment for refractory anaemia with excess of myeloblasts for three years, developed septic shock due to vibrio vulnificus septicaemia. the infection was believed to have been introduced with the ingestion of raw oysters. this organism is comparatively rare, but it can cause serious infection, and is known to be capable of very rapid tissue invasion.19846749004
statistical evaluation of a quality control method for isolation of pathogenic vibrio species on selected thiosulfate-citrate-bile salts-sucrose agars.the recovery of vibrio cholerae, vibrio fluvialis, vibrio parahaemolyticus, and vibrio vulnificus, employing eight strains of each species, was studied by using four brands of thiosulfate-citrate-bile salts-sucrose (tcbs) agar prepared according to manufacturers' instructions and following a standardized procedure. a standardized broth inoculum of each strain was placed on duplicate plates of each brand of tcbs agar and also on tryptic soy agar (difco laboratories) containing 1% (wt/vol) nacl, t ...19826761362
vibrio vulnificus (lactose-positive vibrio) and vibrio parahaemolyticus differ in their susceptibilities to human serum.eleven vibrio vulnificus (lactose-positive vibrio) strains were less susceptible to the bactericidal activity of normal human serum or serum treated with magnesium-ethyleneglycol-bis (beta-aminoethyl ether)-n,n'-tetraacetic acid than were six vibrio parahaemolyticus strains.19816788703
[clinical and bacteriological studies on a case with infectious disease caused by vibrio vulnificus]. 19826819326
marine noncholera vibrio infections in florida.in the past decade, there has been a dramatic increase in the number of reported cases of clinical illness from noncholera (marine) vibrio infections, leading to a greater recognition of this potentially lethal disease. the wide spectrum of pathogenicity of this organism is reflected in the six cases in this report, varying from simple gastroenteritis to focal necrotizing cellulitis to fatal septicemia. we have reviewed the fundamental clinical differences between vibrio vulnificus and other non ...19836828895
extraintestinal infections due to halophilic vibrios.to compare the clinical and epidemiologic features, we reviewed the hospital records and interviewed 18 patients with extraintestinal infections caused by three species of halophilic vibrios. vibrio vulnificus, the organism most frequently isolated in virginia during the six-year study period, caused primary septicemia in three patients. fifteen patients had soft tissue infections, most of which followed injuries that were contaminated by seawater and mostly caused by v vulnificus and v parahaem ...19836844963
distribution of vibrio vulnificus and other lactose-fermenting vibrios in the marine environment.during the summer of 1981, 3,887 sucrose-negative vibrios were isolated from seawater, sediment, plankton, and animal samples taken from 80 sites from miami, fla., to portland, maine. of these, 4.2% were able to ferment lactose. the lactose-positive strains isolated from the various samples correlated positively with ph and turbidity of the water, vibrios in the sediment and oysters, and total bacterial counts in oysters. negative correlations were obtained for water salinity. numerical taxonomy ...19836847190
antibiotic efficacy against vibrio vulnificus in the mouse: superiority of tetracycline.seven antimicrobial agents, all effective against vibrio vulnificus in vitro, were compared for in vivo efficacy in mice experimentally infected with v. vulnificus strain b3547. mice were injected s.c. with 1 x 10(8) cells, and i.p. injection of antimicrobials was begun 1.5 hr later when mice were bacteremic and had edematous lesions at the injection site. the study was done in two phases. phase i was a dose-ranging experiment, using single injections within the range (on a body weight-adjusted ...19836864521
new selective plating medium for isolation of vibrio vulnificus biogroup 1.a new plating medium (vv agar) has been developed as an alternative to thiosulfate-citrate-bile salts-sucrose (tcbs) agar for the isolation of vibrio vulnificus. salicin (2% wt/vol) is employed as the source of carbohydrate, with potassium tellurite (0.0005% wt/vol), crystal violet (0.00015% wt/vol), oxgall (0.8% wt/vol), and a ph of 8.6 to inhibit growth of gram-positive and gram-negative organisms other than v. vulnificus. because strains of v. vulnificus do not strongly ferment salicin in vv ...19836874897
vibrio vulnificus infection. case report and update since 1970.vibrio vulnificus infections is being reported with increasing frequency in coastal regions of the united states. raw seafood consumption, particularly raw oysters, and wounds acquired in a marine environment predispose to infection. patients with advanced liver disease are at increased risk of developing septicemia. v. vulnificus is a virulent pathogen producing significant morbidity and mortality; its virulence relates in part to the production of exotoxin. skin lesions occur early in the clin ...19836886115
detection of extracellular toxin(s) produced by vibrio vulnificus.conditions are described for the production, in high titers, a heat-labile, antigenic, extracellular toxin(s) by vibrio vulnificus, a recently recognized human pathogen. bacteriologically sterile culture filtrate preparations obtained from mid-logarithmic-phase cultures of the bacterium possessed cytolytic activity against mammalian erythrocytes, cytotoxic activity for chinese hamster ovary cells, vascular permeability factor activity in guinea pig skin, and lethal activity for mice. the specifi ...19817024134
diluent composition for use of api 20e in characterizing marine and estuarine bacteria.nine chemically defined inoculation diluents, with compositions ranging from 0.85% nacl to 35% marine salts, were used to evaluate the influence of diluent composition on the biochemical profiles of 30 marine and estuarine bacterial strains, including species of vibrio, aeromonas, allomonas, and photobacterium. results demonstrated that a 20% marine salts diluent enabled the characterization of halophilic strains normally nonreactive by the api 20e system. furthermore, the use of 20% marine salt ...19827125655
vibrio vulnificus biogroup 2: new biogroup pathogenic for eels.clinical and nonclinical isolates of the lactose-positive vibrio vulnificus were compared with vibrio strains isolated from lesions on eels (anguilla japonica) cultured commercially in japan. strains were compared phenotypically and antigenically, for pathogenicity to mice and eels, and for genetic relatedness. the strains isolated from diseased eels differed phenotypically from the original species description of v. vulnificus in that they were negative for indole production, ornithine decarbox ...19827138004
disease caused by a marine vibrio--vibrio vulnificus. 19827144852
distribution and ecology of vibrio vulnificus and other lactose-fermenting marine vibrios in coastal waters of the southeastern united states.water, sediment, plankton, and animal samples from five coastal sites from north carolina to georgia were sampled for their lactose-fermenting vibrio populations. over 20% of all vibrios tested were sucrose negative and o-nitrophenyl-beta-d-galactopyranoside (onpg) positive, suggesting identification as the human pathogen vibrio vulnificus. these vibrios were isolated from all sample sites and sources (water, sediment, plankton, and animals). correlations with several of 19 environmental paramet ...19827159083
isolation and characterization of vibrio vulnificus from two florida estuaries.vibrio vulnificus was enumerated in seawater and shellfish from two florida estuaries at selected seasonal intervals. there were significant fluctuations in the presence and numbers of v. vulnificus. relatively high seawater temperature and salinity favored the presence of v. vulnificus in both seawater and shellfish samples.19827159088
vibrio vulnificus septicemia in a patient with liver cirrhosis. 19827187150
lethal cold stress of vibrio vulnificus in oysters.studies were conducted on the survival of vibrio vulnificus, an estuarine human pathogen, in oyster homogenates held at 4 degrees c. results indicated a rapid and dramatic decrease in viability not attributable to either cold shock or the oyster homogenate alone but to a combination of the two. such a decline was not observed with vibrio parahaemolyticus. chilled v. vulnificus cells were unable to repair themselves in brain heart infusion broth at 37 degrees c. v. vulnificus cells incubated on w ...19817224632
acute bacterial myositis caused by vibrio vulnificus. 19817241733
edema and hemoconcentration in mice experimentally infected with vibrio vulnificus.vibrio vulnificus (lactose-positive vibrio), a recently recognized pathogenic marine species, produced extreme hemoconcentration and death within 3 to 6 h after subcutaneous or intraperitoneal injection of 10(8) viable cells into mice; hemotocrit values approached 70% (normal, 45%). about 1 ml of edema fluid accumulated at the site of each subcutaneous injection, and locally increased vascular permeability was demonstrated by a skin bluing assay, using evans blue dye. a corresponding fluid accum ...19817251164
wound infection and septic shock due to vibrio vulnificus.vibrio vulnificus is an organism commonly found in the marine environment whose pathogenic potential for humans has been recently recognized. two patients are described who developed rapidly progressing wound infections and bacteremia due to this halophilic, lactose-positive vibrio. the clinical manifestations of the resulting infection differed from patterns reported by other authors.19817258496
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