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[new therapeutic possibilities in idiopathic nephrotic syndrome relapse]. 20123440223
[clinical analysis of 334 aged psychiatric inpatients in the past 35 years]. 20123440409
destructive chronic borrelia meningoencephalitis in a child untreated for 15 years.a case of borrelia spirochetosis with recurring episodes of progressively destructive chronic meningoencephalitis, untreated for 15 years, is presented. the patient, now 23 years old, represents an example of the natural course of the disease and may serve as a reminder of the diagnosis in retrospective cases as well as prospectively for acute and chronic states of serous meningitis/meningoencephalitis both in children and adults.19873441752
identification of an autonomously replicating sequence near a histone gene of physarum polycephalum.fragments of dna which function as autonomous replication sequences in yeast were cloned from physarum polycephalum. the ars activity is located in a 1.2 kbp fragment extending 1.5 kbp to 2.7 kbp upstream of the 5' end of a histone h4 gene. our recent finding that a replication origin is located at a distance less than 3 kbp of this histone gene suggests that the ars element identified coincides with a specialized replication origin and can be used to direct chromosome replication in physarum po ...19863442825
surveillance of food poisoning and other food-borne diseases in singapore.the more important food-borne diseases in singapore are food poisoning, enteric fever, cholera and hepatitis a. bacterial food poisoning caused by staphylococcus aureus, salmonella and vibrio parahaemolyticus is prevalent, but chemical poisoning due to ingestion of toxic plants and animals is uncommon. enteric fevers have been brought under control. an increasing proportion of the cases reported in recent years were imported from southeast asia and the indian subcontinent. cholera continues to b ...19873446000
observation on a 65-kilodalton protein isolated from kanagawa positive strains of vibrio parahaemolyticus.crude hemolysin from four kp+ strains of vibrio parahaemolyticus belonging to serotype 02:k3 exhibited a major protein band (molecular weight, 65 kilodaltons (kda] in addition to a previously known thermostable direct hemolysin band (molecular weight, 21 kda) in sds - polyacrylamide slab gel electrophoresis. these strains showed maximum virulence leading to 100% mouse lethality within 2-6 h. it is hypothesized that this 65-kda protein may play a vital role in the pathogenesis of the disease caus ...19873446347
[liver metastases in computerized tomography--an analytic image assessment]. 20123448621
screening of vibrio parahaemolyticus isolates for plasmids. 19873450594
coronary artery disease presenting with exercise induced complete heart block. a case report. 20123454398
[studies on the blood constituents of the neonates delivered by the induced delivery of the defense medical college method].for the assessment of the influence of the defense medical college planned delivery method upon neonates, the measurement of the blood constituents of the umbilical cord was conducted. statistically speaking, no marked differences were seen between the neonates delivered by the defense medical college method and neonates delivered naturally. the blood constituents investigated were: blood cells, activity of various enzymes, other blood constituents and electrolytes.20123457089
gilles de la tourette's syndrome and schizophrenia.a gilles de la tourette's syndrome (ts) patient is described who experienced a schizophrenic episode 11 years after ts onset. analogies and differences between the two syndromes are reviewed, leading to the conclusion that ts is a definite entity independent from schizophrenia, but that they share some common features of symptomatology and pathophysiology and have closely related anatomical lesions.20123457099
paroxysmal myoclonic dystonia with vocalisations: new entity or variant of preexisting syndromes?from among 1377 patients with movement disorders, four patients had an unusual movement disorder characterised by paroxysmal bursts of involuntary, regular, repetitive, rhythmic, bilateral, coordinated, simultaneous, stereotypic myoclonus and vocalisations, often associated with tonic symptoms, interference with voluntary functioning, presence of hyperactivity, attention and learning disabilities, and resistance to treatment with haloperidol and other drugs. this symptom complex may represent a ...20123457101
unraveling the facts about homosexuality. 20123460122
loss of intercalated membrane particles by treatment with phorbols.because brief exposure to phorbol esters renders normal cells vulnerable to deformation and cytolysis by lymphocytes, it was postulated that these tumor promoters might cause a hitherto unrecognized physical alteration in membrane architecture. to investigate this possibility, four tissue culture cell lines (k-562 erythroleukemia cells, melanoma cells, n1121 adult fibroblasts, and normal fetal fibroblasts) and three blood cell types (lymphocytes, monocytes, and platelets) were subjected to freez ...20123462729
staging of leukemic progenitor cells in acute myeloid leukemia by phenotyping with myeloid monoclonal antibodies.we studied the immune phenotype of leukemic progenitor cells (aml-cfu-l) in 16 cases of acute myeloid leukemia (aml) using 12 myeloid monoclonal antibodies (mcabs) in a complement-mediated cytotoxicity assay. on the basis of their reactivities with normal day-14 (d14) and day-7 (d7) myeloid progenitor cells (cfu-gm), these mcabs could be classified into three groups: six mcabs reacted strongly with "early" antigens on d14-cfu-gm, two mcabs reacted only with "late" antigens on d7-cfu-gm, while fo ...20123464449
[human gingival pigmentation due to electrochemical degradation. immunological study of biopsies using monoclonal antibodies]. 19863464603
passive smoking. 20123466081
un fleur du mal--gyromitrin poisoning. 20123467205
the new journalism. 20123468402
immunohistochemical demonstration of pyloric gland-type cells with low-pepsinogen isozyme 1 in preneoplastic and neoplastic tissues of rat stomachs treated with n-methyl-n'-nitro-n-nitrosoguanidine.the appearance of pyloric gland-type cells with a low pepsinogen isozyme 1 (pg 1) content in the stomach mucosa of f344/du rats during stomach carcinogenesis was examined by a combination of paradoxical concanavalin a (con a) staining and immunohistochemical staining for pg 1. male f344 rats were given drinking water containing 100 micrograms n-methyl-n'-nitro-n-nitrosoguanidine [(mnng) cas: 70-25-7]/ml for 30 weeks and then normal tap water and were killed in week 10, 20, 30, 40, 50, or 70. unt ...19873470552
considerations for the apprehensive x-ray patient. 20123471645
mouth opening after release of maxillomandibular fixation in fracture patients.three hundred eleven patients with mandibular fractures were studied prospectively to ascertain the influence of jaw immobilization on mouth opening. maxillomandibular fixation caused a significant reduction in mouth opening whereas open reduction did not. furthermore, there appeared to be a relationship between the duration of immobilization and the degree of reduction of mouth opening such that the shorter the duration of fixation, the less the reduction.20123471923
reflections on infections by the sea. or another form of seasickness. 19873473305
[geriatric pharmacology]. 20123475806
[long-term results of acute dental trauma]. 20123478237
[oral surgery in children's dentistry]. 20123478241
staff salaries and benefits: national and regional survey. 20123478249
subcutaneous nonparenchymal hemangioma of the breast. 20123478625
actions of prostaglandins e2 and f2 alpha on release of 14c-labelled mucins from rat submandibular salivary acini in vitro.mucin secretion was studied in vitro using well-characterized preparations of isolated acini. pge2 significantly (p less than 0.05) increased release of [14c]-glucosamine labelled mucins at the highest concentration tested (10(-5) m), but was ineffective at lower doses (10(-9)-10(-6) m). pgf2 alpha had no effect on mucin secretion over this concentration range. pge2 (10(-9)-10(-5) m) did not modify isoproterenol stimulated mucin secretion. the cyclooxygenase inhibitor indomethacin (10(-7)-10(-5) ...19873482153
management of opportunistic infections complicating the acquired immunodeficiency syndrome.therapy of opportunistic infection in patients with the acquired immunodeficiency syndrome is frustrating, and there is no convincing evidence that aggressive treatment and/or prophylaxis other than for pneumocystis infection can significantly prolong life. while much clinical effort is expended on treating sequential life-threatening infections, the overall course is usually progressively downhill. thus, any real impact on the disease should be aimed at the causative viral agent, because it is ...19863485749
nifedipine and thallium-201 myocardial perfusion in progressive systemic sclerosis.heart disease in patients with progressive systemic sclerosis may be due in part to myocardial ischemia caused by a disturbance of the coronary microcirculation. to determine whether abnormalities of myocardial perfusion in this disorder are potentially reversible, we evaluated the effect of the coronary vasodilator nifedipine on myocardial perfusion assessed by thallium-201 scanning in 20 patients. thallium-201 single-photon-emission computerized tomography was performed under control condition ...20123486363
[pathogenesis of negative washout rate in stress thallium emission computed tomography of coronary artery disease--correlation with cine coronary angiographic findings]. 20123486404
trimethoprim used for selective decontamination of the digestive tract in rats: possible route of excretion.selective elimination of enterobacteriaceae species from the digestive tract of rats has been accomplished by oral treatment with trimethoprim (235 mg/kg body weight/day) within 6 days. in the present study it was investigated whether this elimination was mainly due to antimicrobial activity of trimethoprim excreted with the gastrointestinal mucus or mainly by non-absorbed trimethoprim in the lumen contents. by means of whole gut irrigation (wgi) the lumen contents were washed out, followed by m ...19873497436
the wearing of spectacles in different social and educational groups in a sample of the population of central finland.on the basis of information gathered from a questionnaire study of 6875 people aged from 7 to 46 years and living in central finland, it was seen that the wearing of spectacles has much increased during the last five decades. it is calculated that the wearing of spectacles is still on the increase in the population. more females than males wore spectacles in all the age groups studied. the higher the education the more common was the wearing of spectacles. poor distant vision was the main reason ...20123497441
experience with isoxicam and catabolin.1 synovial cells produce a protein factor, catabolin, that induces chondrocytes to resorb their own matrix with the release of glycosaminoglycan (gag). 2 studies were performed to determine the effect of isoxicam, a new nsaid, on gag production in a catabolin system utilizing tissue culture of bovine nasal septum in a medium containing pooled synovial tissue from young pigs. 3 using fresh medium containing no synovial tissue, the release of gag by inherent cartilage breakdown was 49.7% after 8 d ...19863497659
central nervous system trauma.traumatic injury to the central nervous system causes immediate damage and sets in motion a complex series of pathophysiologic events that result in further neuronal injury. this secondary damage seems to be related to changes in blood flow and pressure on a systemic, regional, and microvascular level. currently, there is evidence that these changes are, in part, mediated by endogenous opioids and arachidonic acid metabolites, namely thromboxane a2. medical management is generally designed to in ...20123497697
necrotizing lymphadenitis (kikuchi's disease). report of four cases of an unusual pseudolymphomatous lesion and immunologic marker studies.the clinical and histologic features of four cases of necrotizing lymphadenitis (kikuchi's disease), an unusual pseudolymphomatous lesion, are presented. three patients were female and one was male. all were under 40 years of age. cervical and juxtaparotid lymph nodes were affected. immunological staining in two cases demonstrated a population of t cells and monocytes in the necrotic areas. necrotizing lymphadenitis is a peculiar reactive condition with a predilection for cervical lymph nodes in ...20123499129
analysis of leukemic blast growth factor (lbgf) and autocrine secretion of csf by leukemic blasts. 20123502308
the effects of backward pairings on the conditioning of the albino rabbit's jaw movement and nictitating membrane responses. 19873502901
[individual preventive examinations of school-age children accompanied by their parents]. 20123502955
murine "housekeeping" enzyme (genetic locus: idh-1) is regulated in an allele-specific manner.the murine "housekeeping" enzyme, cytosolic nadp-isocitrate dehydrogenase (e.c.1.1.1.42) (genetic locus: idh-1), exhibited a complex pattern of allele-specific expression. protein electrophoresis on cellulose-acetate gels and determination of relative enzymatic activity by means of densitometry revealed that in heart tissue (but not liver tissue) of certain hybrid crosses the aa-homodimer was underrepresented relative to total enzymatic activity, and the degree of underrepresentation changed dur ...19873502970
a quantitative morphological examination of bovine vulval skin glands.in adult cows the volumes of sweat and sebaceous glands per unit skin surface area (ssa) in the vulva were greater (p less than 0.01) than in the neck, lip or eyelids. within this perineal region skin gland volumes were greater dorsally than ventrally (p less than 0.01). adult cows had much greater (p less than 0.01) volumes of perineal skin glands per unit ssa than 8 weeks or 6 weeks old heifer calves or steers. there was little or no difference between animal categories in neck skin gland dime ...19873503046
malignant melanomas in the eur-african-malay population of south africa.malignant melanoma is common among the whites of south africa. in the black population, the tumor is much less frequent and occurs predominantly on the lower limb--particularly the sole of the foot. this study brings to light the anomalous situation that among the eur-african-malay population (those of mixed ancestry), malignant melanoma has probably the lowest incidence in the world.20123504109
[sister chromatid exchange and accidental exposure to phenyl-mercury acetate]. 20123504672
the opioid system in the restless legs and nocturnal myoclonus syndromes. 20123505737
report of the committee on the genetic constitution of chromosomes 10, 11, and 12. 19873507274
plasmid patterns, serotyping and kanagawa phenomenon of vibrio parahaemolyticus isolates from man, water and fish in calcutta, india. 19873507428
comparison of the nucleotide sequences of the genes for the thermostable direct hemolysin and the thermolabile hemolysin from vibrio parahaemolyticus.the nucleotide sequences of genes encoding the thermostable direct (tsd) hemolysin and the thermolabile (tl) hemolysin of vibrio parahaemolyticus were determined. from the nucleotide sequence of the tsd hemolysin gene, it was revealed that the preprotein and the mature protein consisted of 189 amino acids and 165 amino acids, and that the molecular weights were 21.1 kda or 18.5 kda, respectively. our data regarding tsd hemolysin were in complete agreement with previously published data. from the ...19863508495
incidental detection of impalpable testicular neoplasm by sonography. 20123510518
third generation cephalosporin antibiotics in surgical practice.the new third generation cephalosporins have a significantly greater spectrum of action against gram-negative bacteria likely to be encountered in surgical infections. this expanded spectrum may permit these drugs to be used in place of combination therapy in patients with polymicrobial infections; however, current evidence does not indicate superior results with these agents over earlier generation choices for surgical prophylaxis. the toxicity profile of these drugs warrants close monitoring f ...20123511763
bacterial diarrhoea.bacterial infections are important causes of diarrhoea in infants and children, particularly in developing countries and in other settings where standards of personal and community hygiene are low. knowledge of bacterial diarrhoeas has been significantly expanded in recent years by the finding that many episodes of acute diarrhoea are due to infections with bacteria which produce enterotoxins that interfere with intestinal fluid and electrolyte transport (the 'enterotoxigenic' diarrhoeas). sever ...19863514008
william osler medal essay. the education, naval service, and early career of william smellie. 20123516279
effect of 1,25-dihydroxyvitamin d3 on insulin secretion: direct or mediated?in order to clarify the role of vitamin d (d) in regulating insulin secretion, we studied the effect of long term (10 days) and short term (3 days) supplementation with d and/or calcium (ca) on insulin secretion from the isolated, perfused pancreas of d- and ca-deficient rats. the influence of the nutritional state induced by d deficiency was also evaluated. the long term supplementation of either d, ca, or both restored the body weight and improved insulin secretion induced by high glucose conc ...19863516655
feasibility of same-day identification of members of the family vibrionaceae by the api 20e system.sixty isolates, comprising nine species of the family vibrionaceae, were tested with the api 20e 5-h same-day procedure (analytab products, plainview, n.y.). included were 27 aeromonas hydrophila isolates, 10 aeromonas sobria isolates, 7 aeromonas caviae isolates, 3 plesiomonas shigelloides isolates, 3 vibrio alginolyticus isolates, 3 vibrio cholerae isolates, 1 vibrio fluvialis isolate, 5 vibrio parahaemolyticus isolates, and 1 vibrio vulnificus isolate. the 5-h profile numbers were specific fo ...19863517061
guanidine hydrochloride denaturation studies of mutant forms of staphylococcal nuclease.several mutant forms of staphylococcal nuclease with one or two defined amino acid substitutions have been purified, and the effects of the altered amino acid sequence on the stability of the folded conformation have been analyzed by guanidine hydrochloride denaturation. two nuc- mutations, which greatly reduced the level of enzyme activity accumulated in e coli colonies carrying a recombinant plasmid with the mutant nuc gene (ie, a nuc- phenotype), both result in protein unfolding at significan ...19863519625
natural killer and t-cell potentiation by monoclonal igg against natural killer cell fcr(igg) or the t3 complex.treatment of human natural killer (nk) cells with monoclonal antibodies of the igg isotype against nk cell-fcr(igg) increased lysis of most haematopoietic target cell lines with high or intermediate background nk susceptibility. treatment of normal non-adherent lymphocytes with an igg anti-t3 monoclonal antibody also increased lysis against the same target cells. potentiating anti-fcr antibodies rapidly modulated fcr activity and the capacity of the cells to act as antibody-dependent killers, al ...19863520802
production of extracellular enzymes and cytotoxicity by vibrio vulnificus.thirty-three strains of vibrio vulnificus of clinical and environmental origin were examined for production of 12 extracellular enzymes of potential importance to the virulence of this bacterium. strains of vibrio vulnificus were consistent in their production of protease, mucinase, lipase, chondroitinase, hyaluronidase, dnase, sulfatase, and hemolysin. no differences between clinical and environmental isolates were noted. although none of the enzymes appeared to correlate with the ability of th ...19863522090
etiology and epidemiology of travelers' diarrhea in asia.travelers' diarrhea in asia has been studied among peace corps volunteers in thailand, japanese travelers, foreign residents in bangladesh, guests in hotels, and members of various tour groups. rates of diarrheal attack of greater than 50% during four- to six-week sojourns were reported for these groups. among travelers with diarrhea, the most commonly isolated pathogen was enterotoxigenic escherichia coli (20%-34%), followed by salmonella (11%-15%), shigella (4%-7%), campylobacter (2%-5%), and ...19863523709
[martin schlenker (1839-1909)]. 20123523751
blood glucose control and diabetic complications.two hypotheses have been advanced to explain the appearance of microvascular complications in diabetic patients with glycemic control. the genetic hypothesis suggests that the development of diabetic complications is genetically determined and independent of diabetic control, whereas the metabolic hypothesis suggests that long-term hyperglycemia causes the subsequent development of small-blood-vessel complications. we review data that either support or reject these hypotheses and suggest a third ...20123524339
reversible and irreversible neuronal damage caused by excitatory amino acid analogues in rat cerebellar slices.slice preparations of the developing rat cerebellum were used to investigate the light and electron microscopic correlates of reversible and irreversible neuronal injury caused by the neurotoxic excitatory amino acid receptor agonists, kainate and n-methyl-d-aspartate. the slices were examined after various periods of exposure to the agonists (up to 30 min) with or without a 90 min recovery period in agonist-free medium. n-methyl-d-aspartate (100 microm) caused necrosis of deep nuclear neurons a ...19863526173
reversible and irreversible neuronal damage caused by excitatory amino acid analogues in rat cerebellar slices.slice preparations of the developing rat cerebellum were used to investigate the light and electron microscopic correlates of reversible and irreversible neuronal injury caused by the neurotoxic excitatory amino acid receptor agonists, kainate and n-methyl-d-aspartate. the slices were examined after various periods of exposure to the agonists (up to 30 min) with or without a 90 min recovery period in agonist-free medium. n-methyl-d-aspartate (100 microm) caused necrosis of deep nuclear neurons a ...19863526173
[effect of dichroa febrifuga l. on chloroquinsensible and chloroquinresistant malaria parasites]. 19863528514
mechanisms of plasmid-mediated antibiotic resistances in vibrio parahaemolyticus.the mechanisms of drug resistance of clinical isolate, vibrio (v.) parahaemolyticus st550, resistant to chloramphenicol (cp), aminoglycoside antibiotics (ags) and beta-lactam antibiotics were investigated. the mechanisms of resistance to cp, ags and beta-lactam antibiotics were dependent on chloramphenicol acetyltransferase (cat), aminoglycoside-3"-adenylyltransferase aad(3") and aminoglycoside-3'-phosphotransferase aph(3') and tem type penicillinase, respectively.19863528768
[renal oncocytoma]. 20123535166
the immunohistochemical detection of lymph node metastases from infiltrating lobular carcinoma of the breast.immunological markers improve specificity and accuracy of cell detection, therefore it is important to evaluate their usefulness in improving standard histological procedures. this study investigates whether immunocytochemical techniques increase the accuracy of detection, in axillary lymph nodes, of metastatic cells from infiltrating breast lobular carcinoma (ilc). fifty cases of ilc reported to be node-negative were selected. new serial sections were cut from a total of 767 lymph nodes, staine ...19863535864
[decreased activity of the renal vasodilation and natriuretic system in normotensive men with a familial history of essential hypertension and decreased na+, k+-cotransport in erythrocytes]. 20133536113
enzyme-linked immunosorbent assay to detect shiga toxin of shigella dysenteriae and related toxins.a sandwich enzyme-linked immunosorbent assay (elisa) was developed for detection of shiga toxin. four species of shigella, escherichia coli, and vibro parahaemolyticus were tested for production of shiga or shiga-like toxin by elisa and vero cell bioassay. in the elisa, most strains of s. dysenteriae and some strains of e. coli isolated from traveler's diarrhea were positive. these elisa-positive strains were positive by vero cell bioassay without exception. some e. coli strains and most v. para ...19873539985
isotope exchange at equilibrium studies with rat muscle adenylosuccinate synthetase.the kinetic mechanism of rat muscle adenylosuccinate synthetase was studied by determining the rates of isotope exchange at equilibrium. a random sequential binding mechanism was indicated for both the forward and reverse reactions. aspartate, adenylosuccinate, gdp, and pi were determined to bind in rapid equilibrium. gtp exchanges with both gdp and pi at the same rate, which is similar to the exchange rate of imp with adenylosuccinate. aspartate exchanges with adenylosuccinate at a higher rate ...19863542024
the complete amino acid sequence of ribosomal protein s12 from bacillus stearothermophilus.the amino acid sequence of ribosomal protein s12 from bacillus stearothermophilus has been completely determined. the sequence data were mainly obtained by manual sequencing of peptides derived from digestion with trypsin, staphylococcus aureas protease and pepsin. a few overlaps of tryptic peptides were established by dna sequence analysis of a chromosomal fragment containing the rpsl gene coding for ribosomal protein s12. the protein contains 138 amino acid residues and has an mr of 15,208. co ...19873542563
blood culture updated. 20123542814
[protein engineering and bioelectronics]. 20123546782
consequences of treatment of gastrointestinal infections.diarrhoeal disease is a common problem in developing countries. as a result of recent advances in diagnostic methodology, the causative agents can now be identified in most cases of acute diarrhoeal diseases. enteric bacterial pathogens are the common cause of gastroenteritis in developing countries. appropriate uses of antibiotics in selected cases of diarrhoea will decrease symptoms or reduce faecal shedding of the organism and prevent spread of infection. antimicrobial agents improve the diar ...19863547620
adult respiratory distress syndrome. a live e coli septic primate model. 19873548404
an immunocytochemical and ultrastructural study of the endocrine pancreas of sparus auratus l. (teleostei).the pancreatic endocrine cells of sparus auratus (gilthead sea bream) are concentrated in two or three principal islets, or brockmann bodies, and numerous smaller islets embedded in the exocrine tissue. insulin-, glucagon-, somatostatin-, and pancreatic polypeptide (pp)-immunoreactive cells were identified in all pancreatic islets of s. auratus using an indirect immunocytochemical (pap) method. insulin-immunoreactive cells were found in the central region of the islets. glucagon-immunoreactive c ...20123549431
respiratory responsiveness in male alcoholics after withdrawal.peripheral and central chemosensitivity were assessed in eight abstinent male alcoholic patients and in seven healthy normal male subjects. hypoxic rebreathing (15% o2, 7% co2) was used to stimulate the peripheral and central chemoreceptors together. hyperoxic rebreathing (93% o2, 7% co2) was used to examine the central chemoreceptor response independently of the peripheral chemoreceptors. minute ventilation was examined in relation to end-tidal paco2 under the two conditions. neither peripheral ...20123551663
[sketches on the history of the training of paramedical personnel in russia]. 20133553835
the morphology and distribution of serotonin-like immunoreactive fibers in the cat dorsal column nuclei.fibers showing serotonin-like immunoreactivity (5-ht-li) are demonstrated in the gracile, cuneate and external cuneate nuclei of the cat using avidin-biotinylated horseradish peroxidase and indirect fluorescence immunohistochemical methods. 5-ht-li fibers are located in all cytoarchitectural subdivisions of the gracile and cuneate nuclei but are restricted to the medial half of the external cuneate nucleus. in all nuclei, 5-ht-li fibers consist of long, varicose strands showing a wide range in t ...19873554006
calcitonin gene-related peptide in the ventral tegmental area: selective modulation of prefrontal cortical dopamine metabolism.the distribution of calcitonin gene-related peptide (cgrp) in the a10 dopamine (da) cell group region of the ventral tegmental area (vta) of the rat was examined using immunohistochemical techniques. cgrp-like immunoreactivity was localized to axons innervating the rostral and dorsal vta. direct administration of cgrp to the vta of the rat resulted in a dose-related increase in da utilization in the medial prefrontal cortex, but not other mesocortical, mesolimbic, or striatal da terminal field r ...19873554009
the role of the ileum in food intake regulation. 20133554018
nutrition classics. the journal of nutrition, volume 91, 1967: the paths to the discovery of vitamins a and d. by elmer verner mccollum. 20133554022
restorative dentistry.various restorative methods like composite crowns, parapulpar pin reconstructions or vast crowns and bridges, are evaluated against each other. also new methods for repair of jaw-fractures in dogs and cats by means of parapulpar pins and composites are discussed.19873554609
prostatic biopsy guided by transrectal ultrasonography using real-time linear scanner.prostatic needle biopsy guided by transrectal ultrasonography using a real-time linear scanner was performed on 257 cases in our outpatient clinic and mass screening program for prostatic diseases. the success rate was 99.2 per cent, and complications occurred in only 2 cases (0.8%) after biopsy. this newly developed method is recommended as being safer and more accurate than conventional ones.20133554701
electrophysiological effects of mexiletine in patients of sinus node dysfunction and intraventricular conduction defects. 20123557516
electrophysiological effects of mexiletine in patients of sinus node dysfunction and intraventricular conduction defects. 20123557516
ranking possible carcinogenic hazards.this review discusses reasons why animal cancer tests cannot be used to predict absolute human risks. such tests, however, may be used to indicate that some chemicals might be of greater concern than others. possible hazards to humans from a variety of rodent carcinogens are ranked by an index that relates the potency of each carcinogen in rodents to the exposure in humans. this ranking suggests that carcinogenic hazards from current levels of pesticide residues or water pollution are likely to ...19873563506
decreased sialic acid content of erythrocytes in patients with aplastic anaemia.the sialic acid content of erythrocytes from patients with aplastic anaemia was determined and compared with those in patients with several haematological disorders and healthy individuals. the sialic acid was released enzymatically with vibrio cholerae sialidase and quantitated by the thiobarbituric acid method (aminoff, 1961). the sialic acid content of normal erythrocytes was 538 +/- 31 nmol/ml of packed erythrocytes. that of erythrocytes from patients with aplastic anaemia was 480 +/- 35 nmo ...19873567088
the end-systolic pressure-volume relationship in conscious dogs.the end-systolic pressure-volume relationship (espvr) has been shown to be an afterload-insensitive descriptor of ventricular inotropic state in the isolated heart. the purpose of this study was to examine the effects of changes in afterload, heart rate, intravascular volume, autonomic tone, and inotropic state on the espvr in conscious dogs. in 30 dogs, left ventricular and pleural pressures were measured with micromanometers, and left ventricular volume was assessed with global ultrasonic crys ...19873568332
flow-cytometric characterization of stimulation, free radical formation, peroxidase activity and phagocytosis of human granulocytes with 2,7-dichlorofluorescein (dcf).a standardized four-step assay for the flow cytometric determination of the oxidative activity of human polymorphonuclear leukocytes (pmnl) from normal human individuals and from septic patients was developed, using 2,7-dichlorofluorescin-diacetate (dcfh-da) as indicator for the intracellular formation of h2o2 and free radicals. spontaneous h2o2 and free radical formation was measured by preincubation of buffy coat pmnls from fresh peripheral venous blood at 37 degrees c and ph 7.4 with 10 micro ...19873569301
amino acid sequence of thermostable direct hemolysin produced by vibrio parahaemolyticus.the complete amino acid sequence of the subunit of thermostable direct hemolysin, a dimeric protein composed of identical subunits isolated from vibrio parahaemolyticus, was determined by sequencing brcn-peptides, their tryptic peptides, and overlaps obtained by achromobacter protease i digestion. the subunit consists of 165 amino acid residues with the sole disulfide bond between cys 151 and cys 161. it is deduced that the biologically active hemolysin is formed by noncovalent association of su ...19873571196
a signal sequence domain essential for processing, but not import, of mitochondrial pre-ornithine carbamyl transferase.studies using deletion mutagenesis indicate that a processing recognition site lies proximal to the normal cleavage position between gln32 and ser33 of pre-ornithine carbamyl transferase (poct). poct cdna was manipulated to delete codons specifying amino acids 22-30 of the signal sequence. the mutant precursor, designated poct delta 22-30, was imported to the matrix compartment by purified mitochondria, but remained largely unprocessed; the low level of processing that was observed did not invol ...19873571328
further improvement of high-speed nmr flow-velocity measurement using a differential phase-encoding technique.an nmr imaging technique applicable to high-velocity flow imaging is described. by subtraction of two phase images obtained by varying the flow-encoding gradient, it is possible to extract much larger ranges of velocity components. this differential phase-encoding technique is tested by experiments in a phantom as well as a human volunteer.19873574062
[diastolic function of the left ventricle in patients with an apical aneurysm after acute anterior wall myocardial infarction]. 20133574068
disseminated intravascular coagulation, antiphospholipid antibodies, and ischaemic necrosis of extremities.a middle aged woman presented with acute, severe, intravascular coagulation leading to ischaemic necrosis of the extremities. pulmonary involvement required artificial ventilation, and there was evidence of hepatic, pancreatic, and renal damage, which resolved without complication. these events may have been triggered by the ingestion of compound diuretic tablets. the finding of the 'lupus anticoagulant' and anticardiolipin antibodies, together with high titre antinuclear factor in the serum, an ...20133579392
electromagnetic articulography: use of alternating magnetic fields for tracking movements of multiple points inside and outside the vocal tract.the purpose of this paper is to present a new electromagnetic device which uses alternating magnetic fields for tracking movements of multiple points inside and outside the vocal tract. it is biologically safe, noninvasive, it does not interfere with speech movements, allows for multiple recording in the same subject, and for easy collection of large amounts of data. it is especially suitable for evaluation of patients with speech motor impairments.20103580838
[para-articular calcinosis of soft tissues in dialyzed patients]. 20133581241
medicolegal dystocia. 20133581551
frequency/amplitude characteristics of postural tremor of the hands in a population of patients with bilateral essential tremor: implications for the classification and mechanism of essential tremor.amplitude/frequency characteristics of postural hand tremor in 59 patients with bilateral essential tremor of various degrees of severity were assessed using accelerometric recordings and spectral analysis. intra-subject comparisons of tremor characteristics between the more and less affected hands were used to control for variability of tremor due to age factors and intersubject differences in amplitude and frequency. statistical analysis distinguished three different patient groups. some patie ...20133585381
macular disease resembling adult foveomacular vitelliform dystrophy in older adults.fifty-three eyes of 31 patients over age 50 with macular disease were reviewed. clinical appearance of the macula was of two types: a yellow slightly elevated lesion (29 eyes) and a pigmented flat lesion with surrounding atrophy (24 eyes). drusen were found in 60% of affected eyes. no familial tendencies were documented. a reduced electro-oculogram (eog) was present in approximately 50% of all eyes tested. fluorescein angiographic findings and differential diagnosis are described. visual prognos ...20133587917
immune hemolysis by isohemagglutinins in factor ix concentrates. 20133590295
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